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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61819425
log Bayes Factor = 15.4159
Chromosome 1   position 114,136,618  (GRCh37) Explore rs61819425 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10.9 Without complications
0.998 0.002 0.000
S60-S69 Injuries to the wrist and hand
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
S00-S09 Injuries to the head
0.989 0.011 0.000
S61 Open wound of wrist and hand
0.986 0.014 0.000
I25 Chronic ischaemic heart disease
0.979 0.021 0.000
I20 Angina pectoris
0.971 0.029 0.000
S61.0 Open wound of finger(s) without damage to nail
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.961 0.039 0.000
G40-G47 Episodic and paroxysmal disorders
0.960 0.040 0.000
I20.9 Angina pectoris, unspecified
0.959 0.041 0.000
M05-M14 Inflammatory polyarthropathies
0.951 0.049 0.000
Chapter XX External causes of morbidity and mortality
0.950 0.050 0.000
J20-J22 Other acute lower respiratory infections
0.950 0.050 0.000
S00 Superficial injury of head
0.933 0.067 0.000
Chapter VII Diseases of the eye and adnexa
0.930 0.070 0.000
I25.2 Old myocardial infarction
0.928 0.072 0.000
J22 Unspecified acute lower respiratory infection
0.920 0.080 0.000
E10.5 With peripheral circulatory complications
0.919 0.081 0.000
H30-H36 Disorders of choroid and retina
0.914 0.086 0.000
M13 Other arthritis
0.910 0.090 0.000
J40-J47 Chronic lower respiratory diseases
0.905 0.095 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.905 0.095 0.000
J30-J39 Other diseases of upper respiratory tract
0.903 0.097 0.000
E65-E68 Obesity and other hyperalimentation
0.901 0.099 0.000
G47 Sleep disorders
0.893 0.107 0.000
E11 Non-insulin-dependent diabetes mellitus
0.891 0.109 0.000
M13.9 Arthritis, unspecified
0.880 0.119 0.000
E10.3 With ophthalmic complications
0.879 0.121 0.000
T66-T78 Other and unspecified effects of external causes
0.878 0.122 0.000
S01 Open wound of head
0.876 0.124 0.000
E50-E64 Other nutritional deficiencies
0.862 0.138 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.859 0.141 0.000
Chapter II Neoplasms
0.857 0.143 0.000
E20-E35 Disorders of other endocrine glands
0.854 0.146 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.854 0.146 0.000
E10.1 With ketoacidosis
0.853 0.147 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.853 0.147 0.000
I73 Other peripheral vascular diseases
0.851 0.149 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.850 0.150 0.000
S68 Traumatic amputation of wrist and hand
0.845 0.155 0.000
S06 Intracranial injury
0.844 0.156 0.000
M06 Other rheumatoid arthritis
0.843 0.157 0.000
S40-S49 Injuries to the shoulder and upper arm
0.842 0.158 0.000
J95-J99 Other diseases of the respiratory system
0.835 0.165 0.000
W00-W19 Falls
0.831 0.169 0.000
J35 Chronic diseases of tonsils and adenoids
0.831 0.169 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.829 0.171 0.000
E66 Obesity
0.829 0.171 0.000
S62 Fracture at wrist and hand level
0.829 0.171 0.000
H33 Retinal detachments and breaks
0.829 0.171 0.000
E70-E90 Metabolic disorders
0.827 0.173 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.825 0.175 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.824 0.176 0.000
S64 Injury of nerves at wrist and hand level
0.824 0.176 0.000
G47.3 Sleep apnoea
0.823 0.177 0.000
S61.8 Open wound of other parts of wrist and hand
0.823 0.177 0.000
E10.2 With renal complications
0.820 0.180 0.000
S00.9 Superficial injury of head, part unspecified
0.820 0.180 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.819 0.181 0.000
I73.9 Peripheral vascular disease, unspecified
0.817 0.183 0.000
G43 Migraine
0.811 0.189 0.000
J44 Other chronic obstructive pulmonary disease
0.809 0.191 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.808 0.192 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.808 0.192 0.000
S09 Other and unspecified injuries of head
0.804 0.196 0.000
W20-W49 Exposure to inanimate mechanical forces
0.804 0.196 0.000
H34 Retinal vascular occlusions
0.802 0.198 0.000
G90-G99 Other disorders of the nervous system
0.801 0.199 0.000
I20.8 Other forms of angina pectoris
0.800 0.199 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.800 0.200 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.795 0.205 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
T78 Adverse effects, not elsewhere classified
0.791 0.209 0.000
G70-G73 Diseases of myoneural junction and muscle
0.789 0.211 0.000
I60-I69 Cerebrovascular diseases
0.788 0.212 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.785 0.215 0.000
E06 Thyroiditis
0.785 0.215 0.000
S20-S29 Injuries to the thorax
0.782 0.218 0.000
H35 Other retinal disorders
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.780 0.220 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.777 0.223 0.000
I24 Other acute ischaemic heart diseases
0.774 0.226 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.772 0.228 0.000
Chapter V Mental and behavioural disorders
0.771 0.229 0.000
E11.5 With peripheral circulatory complications
0.770 0.230 0.000
M65-M68 Disorders of synovium and tendon
0.770 0.230 0.000
S00.0 Superficial injury of scalp
0.770 0.230 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.769 0.231 0.000
Chapter VIII Diseases of the ear and mastoid process
0.767 0.233 0.000
C79 Secondary malignant neoplasm of other sites
0.761 0.239 0.000
M10 Gout
0.759 0.241 0.000
E14 Unspecified diabetes mellitus
0.759 0.241 0.000
H36 Retinal disorders in diseases classified elsewhere
0.759 0.241 0.000
M91-M94 Chondropathies
0.758 0.241 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.755 0.245 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.753 0.247 0.000
J30 Vasomotor and allergic rhinitis
0.752 0.248 0.000
E07 Other disorders of thyroid
0.751 0.249 0.000
J47 Bronchiectasis
0.751 0.249 0.000
I05-I09 Chronic rheumatic heart diseases
0.750 0.250 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.750 0.250 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.749 0.251 0.000
D10-D36 Benign neoplasms
0.749 0.251 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.749 0.251 0.000
M45-M49 Spondylopathies
0.749 0.251 0.000
J43 Emphysema
0.748 0.252 0.000
G20-G26 Extrapyramidal and movement disorders
0.747 0.253 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.747 0.253 0.000
M40-M43 Deforming dorsopathies
0.746 0.254 0.000
M06.9 Rheumatoid arthritis, unspecified
0.744 0.256 0.000
G62 Other polyneuropathies
0.742 0.258 0.000
E11.4 With neurological complications
0.741 0.259 0.000
M86-M90 Other osteopathies
0.738 0.262 0.000
E05.9 Thyrotoxicosis, unspecified
0.738 0.262 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.738 0.262 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.738 0.262 0.000
E53 Deficiency of other B group vitamins
0.736 0.264 0.000
J36 Peritonsillar abscess
0.735 0.265 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.735 0.265 0.000
Chapter XXII Codes for special purposes
0.734 0.265 0.000
S01.5 Open wound of lip and oral cavity
0.734 0.266 0.000
H33.2 Serous retinal detachment
0.732 0.268 0.000
I63 Cerebral infarction
0.732 0.268 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.732 0.268 0.000
G30-G32 Other degenerative diseases of the nervous system
0.732 0.268 0.000
H43-H45 Disorders of vitreous body and globe
0.729 0.271 0.000
H10-H13 Disorders of conjunctiva
0.728 0.272 0.000
S80-S89 Injuries to the knee and lower leg
0.727 0.273 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.726 0.274 0.000
E66.9 Obesity, unspecified
0.724 0.276 0.000
S01.3 Open wound of ear
0.722 0.278 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.719 0.281 0.000
S02 Fracture of skull and facial bones
0.719 0.281 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.4 With neurological complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
E03.8 Other specified hypothyroidism
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
Y86 Sequelae of other accidents
0.716 0.284 0.000
G47.9 Sleep disorder, unspecified
0.716 0.284 0.000
E66.8 Other obesity
0.716 0.284 0.000
S69 Other and unspecified injuries of wrist and hand
0.715 0.284 0.000
S67 Crushing injury of wrist and hand
0.715 0.284 0.000
S65 Injury of blood vessels at wrist and hand level
0.715 0.284 0.000
S60 Superficial injury of wrist and hand
0.715 0.284 0.000
S42 Fracture of shoulder and upper arm
0.715 0.285 0.000
S00.8 Superficial injury of other parts of head
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
J98 Other respiratory disorders
0.712 0.288 0.000
W19 Unspecified fall
0.712 0.288 0.000
C64-C68 Malignant neoplasms of urinary tract
0.712 0.288 0.000
H33.3 Retinal breaks without detachment
0.712 0.288 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.289 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.710 0.290 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.710 0.290 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
M05 Seropositive rheumatoid arthritis
0.709 0.290 0.000
S08 Traumatic amputation of part of head
0.709 0.291 0.000
S07 Crushing injury of head
0.709 0.291 0.000
S05 Injury of eye and orbit
0.709 0.291 0.000
S04 Injury of cranial nerves
0.709 0.291 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.709 0.291 0.000
J35.1 Hypertrophy of tonsils
0.709 0.291 0.000
C60-C63 Malignant neoplasms of male genital organs
0.709 0.291 0.000
S61.7 Multiple open wounds of wrist and hand
0.707 0.293 0.000
I10-I15 Hypertensive diseases
0.706 0.294 0.000
J84 Other interstitial pulmonary diseases
0.706 0.294 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.705 0.295 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.703 0.297 0.000
S50-S59 Injuries to the elbow and forearm
0.702 0.298 0.000
I25.6 Silent myocardial ischaemia
0.702 0.298 0.000
I25.5 Ischaemic cardiomyopathy
0.702 0.298 0.000
I25.4 Coronary artery aneurysm
0.702 0.298 0.000
I25.3 Aneurysm of heart
0.702 0.298 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.702 0.298 0.000
S06.5 Traumatic subdural haemorrhage
0.701 0.299 0.000
J42 Unspecified chronic bronchitis
0.701 0.299 0.000
S62.6 Fracture of other finger
0.700 0.300 0.000
J60-J70 Lung diseases due to external agents
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.699 0.301 0.000
G45.3 Amaurosis fugax
0.697 0.303 0.000
E22 Hyperfunction of pituitary gland
0.696 0.303 0.000
I20.1 Angina pectoris with documented spasm
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.305 0.000
M60-M63 Disorders of muscles
0.693 0.307 0.000
M00-M03 Infectious arthropathies
0.693 0.307 0.000
E80.4 Gilbert's syndrome
0.693 0.307 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.692 0.308 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.690 0.310 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
E16 Other disorders of pancreatic internal secretion
0.690 0.310 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.689 0.311 0.000
G41 Status epilepticus
0.689 0.311 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.688 0.311 0.000
I78 Diseases of capillaries
0.686 0.313 0.000
D12.4 Descending colon
0.685 0.315 0.000
W25 Contact with sharp glass
0.684 0.316 0.000
H34.8 Other retinal vascular occlusions
0.683 0.317 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.683 0.317 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.682 0.318 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.682 0.318 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
M12 Other specific arthropathies
0.682 0.318 0.000
M11 Other crystal arthropathies
0.682 0.318 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.682 0.318 0.000
M08 Juvenile arthritis
0.682 0.318 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.319 0.000
Y35-Y36 Legal intervention and operations of war
0.681 0.319 0.000
Y10-Y34 Event of undetermined intent
0.681 0.319 0.000
Y00-Y09 Assault
0.681 0.319 0.000
X85-X99 Assault
0.681 0.319 0.000
X60-X84 Intentional self-harm
0.681 0.319 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.681 0.319 0.000
X50-X57 Overexertion, travel and privation
0.681 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.681 0.319 0.000
X30-X39 Exposure to forces of nature
0.681 0.319 0.000
X20-X29 Contact with venomous animals and plants
0.681 0.319 0.000
X10-X19 Contact with heat and hot substances
0.681 0.319 0.000
X00-X09 Exposure to smoke, fire and flames
0.681 0.319 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.681 0.319 0.000
W75-W84 Other accidental threats to breathing
0.681 0.319 0.000
W65-W74 Accidental drowning and submersion
0.681 0.319 0.000
W50-W64 Exposure to animate mechanical forces
0.681 0.319 0.000
V98-V99 Other and unspecified transport accidents
0.681 0.319 0.000
V95-V97 Air and space transport accidents
0.681 0.319 0.000
V90-V94 Water transport accidents
0.681 0.319 0.000
V80-V89 Other land transport accidents
0.681 0.319 0.000
V70-V79 Bus occupant injured in transport accident
0.681 0.319 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.681 0.319 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.681 0.319 0.000
V40-V49 Car occupant injured in transport accident
0.681 0.319 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.681 0.319 0.000
V01-V09 Pedestrian injured in transport accident
0.681 0.319 0.000
J21 Acute bronchiolitis
0.681 0.319 0.000
J20 Acute bronchitis
0.681 0.319 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.680 0.320 0.000
S01.2 Open wound of nose
0.679 0.321 0.000
D22 Melanocytic naevi
0.679 0.321 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.678 0.322 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.678 0.322 0.000
J35.0 Chronic tonsillitis
0.675 0.325 0.000
I77 Other disorders of arteries and arterioles
0.675 0.325 0.000
Y43 Primarily systemic agents
0.674 0.326 0.000
G44 Other headache syndromes
0.673 0.327 0.000
G43.9 Migraine, unspecified
0.671 0.328 0.000
S09.9 Unspecified injury of head
0.671 0.328 0.000
T78.3 Angioneurotic oedema
0.670 0.330 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.670 0.330 0.000
S70-S79 Injuries to the hip and thigh
0.669 0.330 0.000
S00.7 Multiple superficial injuries of head
0.669 0.331 0.000
S00.5 Superficial injury of lip and oral cavity
0.669 0.331 0.000
S00.4 Superficial injury of ear
0.669 0.331 0.000
S00.3 Superficial injury of nose
0.669 0.331 0.000
S00.1 Contusion of eyelid and periocular area
0.669 0.331 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.668 0.331 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.668 0.332 0.000
I63.9 Cerebral infarction, unspecified
0.667 0.333 0.000
H55-H59 Other disorders of eye and adnexa
0.667 0.333 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.667 0.333 0.000
T78.4 Allergy, unspecified
0.666 0.334 0.000
S61.1 Open wound of finger(s) with damage to nail
0.666 0.334 0.000
E11.3 With ophthalmic complications
0.665 0.335 0.000
W07 Fall involving chair
0.664 0.336 0.000
W19.9 Unspecified place
0.664 0.336 0.000
E23 Hypofunction and other disorders of pituitary gland
0.664 0.336 0.000
M07 Psoriatic and enteropathic arthropathies
0.662 0.338 0.000
E61 Deficiency of other nutrient elements
0.660 0.340 0.000
G62.9 Polyneuropathy, unspecified
0.659 0.341 0.000
M06.0 Seronegative rheumatoid arthritis
0.657 0.343 0.000
G61 Inflammatory polyneuropathy
0.656 0.344 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.655 0.344 0.000
H31 Other disorders of choroid
0.655 0.344 0.000
H30 Chorioretinal inflammation
0.655 0.344 0.000
E88 Other metabolic disorders
0.654 0.346 0.000
D12.2 Ascending colon
0.653 0.347 0.000
M13.8 Other specified arthritis
0.652 0.347 0.000
M13.1 Monoarthritis, not elsewhere classified
0.652 0.347 0.000
M13.0 Polyarthritis, unspecified
0.652 0.347 0.000
M15-M19 Arthrosis
0.651 0.349 0.000
E78.0 Pure hypercholesterolaemia
0.651 0.349 0.000
H34.2 Other retinal artery occlusions
0.650 0.350 0.000
S40 Superficial injury of shoulder and upper arm
0.649 0.351 0.000
J41 Simple and mucopurulent chronic bronchitis
0.649 0.351 0.000
J46 Status asthmaticus
0.649 0.351 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.649 0.351 0.000
I72 Other aneurysm
0.649 0.351 0.000
I70 Atherosclerosis
0.649 0.351 0.000
J37 Chronic laryngitis and laryngotracheitis
0.647 0.353 0.000
H36.0 Diabetic retinopathy
0.647 0.353 0.000
J33 Nasal polyp
0.647 0.353 0.000
E29 Testicular dysfunction
0.646 0.354 0.000
V10-V19 Pedal cyclist injured in transport accident
0.646 0.354 0.000
E67 Other hyperalimentation
0.646 0.354 0.000
E68 Sequelae of hyperalimentation
0.646 0.354 0.000
E65 Localised adiposity
0.646 0.354 0.000
E53.8 Deficiency of other specified B group vitamins
0.646 0.354 0.000
Y57 Other and unspecified drugs and medicaments
0.645 0.355 0.000
S01.8 Open wound of other parts of head
0.645 0.355 0.000
Q60-Q64 Congenital malformations of the urinary system
0.645 0.355 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.645 0.355 0.000
J30.1 Allergic rhinitis due to pollen
0.644 0.355 0.000
G70 Myasthenia gravis and other myoneural disorders
0.644 0.356 0.000
H35.8 Other specified retinal disorders
0.643 0.357 0.000
G47.8 Other sleep disorders
0.640 0.360 0.000
G47.4 Narcolepsy and cataplexy
0.640 0.360 0.000
G47.2 Disorders of the sleep-wake schedule
0.640 0.360 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.640 0.360 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.640 0.360 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.640 0.360 0.000
J40 Bronchitis, not specified as acute or chronic
0.640 0.360 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.639 0.361 0.000
E11.8 With unspecified complications
0.639 0.361 0.000
E11.7 With multiple complications
0.639 0.361 0.000
E11.6 With other specified complications
0.639 0.361 0.000
E11.2 With renal complications
0.639 0.361 0.000
E11.1 With ketoacidosis
0.639 0.361 0.000
E11.0 With coma
0.639 0.361 0.000
E04 Other non-toxic goitre
0.638 0.362 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.637 0.363 0.000
G43.1 Migraine with aura [classical migraine]
0.636 0.364 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.636 0.364 0.000
S42.2 Fracture of upper end of humerus
0.635 0.365 0.000
J43.9 Emphysema, unspecified
0.635 0.365 0.000
C67 Malignant neoplasm of bladder
0.632 0.368 0.000
H35.0 Background retinopathy and retinal vascular changes
0.632 0.368 0.000
M19 Other arthrosis
0.632 0.368 0.000
M13.93 Arthritis, unspecified (Forearm)
0.631 0.369 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.631 0.369 0.000
E06.3 Autoimmune thyroiditis
0.630 0.369 0.000
T75 Effects of other external causes
0.630 0.370 0.000
T74 Maltreatment syndromes
0.630 0.370 0.000
T73 Effects of other deprivation
0.630 0.370 0.000
T70 Effects of air pressure and water pressure
0.630 0.370 0.000
T69 Other effects of reduced temperature
0.630 0.370 0.000
T67 Effects of heat and light
0.630 0.370 0.000
T71 Asphyxiation
0.630 0.370 0.000
T68 Hypothermia
0.630 0.370 0.000
T66 Unspecified effects of radiation
0.630 0.370 0.000
E55 Vitamin D deficiency
0.629 0.371 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.629 0.371 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.629 0.371 0.000
M67 Other disorders of synovium and tendon
0.629 0.371 0.000
S92 Fracture of foot, except ankle
0.629 0.371 0.000
Y85 Sequelae of transport accidents
0.629 0.371 0.000
S01.9 Open wound of head, part unspecified
0.628 0.372 0.000
S01.7 Multiple open wounds of head
0.628 0.372 0.000
S01.4 Open wound of cheek and temporomandibular area
0.628 0.372 0.000
S01.1 Open wound of eyelid and periocular area
0.628 0.372 0.000
S62.60 Fracture of other finger (closed)
0.627 0.373 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.627 0.373 0.000
J39 Other diseases of upper respiratory tract
0.626 0.374 0.000
G25 Other extrapyramidal and movement disorders
0.626 0.374 0.000
J09-J18 Influenza and pneumonia
0.626 0.374 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.625 0.374 0.000
S64.4 Injury of digital nerve of other finger
0.623 0.376 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.623 0.377 0.000
I87 Other disorders of veins
0.623 0.377 0.000
M10.9 Gout, unspecified
0.622 0.378 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.621 0.378 0.000
M48 Other spondylopathies
0.621 0.379 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.621 0.379 0.000
M13.98 Arthritis, unspecified (Other)
0.621 0.379 0.000
M19.9 Arthrosis, unspecified
0.620 0.380 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.620 0.380 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.619 0.380 0.000
J80 Adult respiratory distress syndrome
0.619 0.381 0.000
S63.6 Sprain and strain of finger(s)
0.619 0.381 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.618 0.382 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.618 0.382 0.000
E63 Other nutritional deficiencies
0.618 0.382 0.000
E56 Other vitamin deficiencies
0.618 0.382 0.000
E51 Thiamine deficiency
0.618 0.382 0.000
E50 Vitamin A deficiency
0.618 0.382 0.000
E60 Dietary zinc deficiency
0.618 0.382 0.000
E59 Dietary selenium deficiency
0.618 0.382 0.000
E58 Dietary calcium deficiency
0.618 0.382 0.000
E54 Ascorbic acid deficiency
0.618 0.382 0.000
E52 Niacin deficiency [pellagra]
0.618 0.382 0.000
G60 Hereditary and idiopathic neuropathy
0.616 0.384 0.000
G64 Other disorders of peripheral nervous system
0.616 0.384 0.000
D12.3 Transverse colon
0.615 0.385 0.000
H60-H62 Diseases of external ear
0.615 0.385 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.614 0.385 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.614 0.385 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.614 0.385 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.614 0.386 0.000
Y40 Systemic antibiotics
0.614 0.386 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.614 0.386 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.614 0.386 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.613 0.387 0.000
E34 Other endocrine disorders
0.613 0.387 0.000
E32 Diseases of thymus
0.613 0.387 0.000
E31 Polyglandular dysfunction
0.613 0.387 0.000
E30 Disorders of puberty, not elsewhere classified
0.613 0.387 0.000
E28 Ovarian dysfunction
0.613 0.387 0.000
E27 Other disorders of adrenal gland
0.613 0.387 0.000
E26 Hyperaldosteronism
0.613 0.387 0.000
E25 Adrenogenital disorders
0.613 0.387 0.000
E24 Cushing's syndrome
0.613 0.387 0.000
E20 Hypoparathyroidism
0.613 0.387 0.000
T93 Sequelae of injuries of lower limb
0.612 0.388 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.611 0.388 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.611 0.388 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.611 0.388 0.000
G45.0 Vertebro-basilar artery syndrome
0.611 0.388 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.610 0.389 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.610 0.390 0.000
I73.8 Other specified peripheral vascular diseases
0.610 0.390 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.610 0.390 0.000
S62.3 Fracture of other metacarpal bone
0.610 0.390 0.000
E05.8 Other thyrotoxicosis
0.610 0.390 0.000
E05.5 Thyroid crisis or storm
0.610 0.390 0.000
E05.4 Thyrotoxicosis factitia
0.610 0.390 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.610 0.390 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.610 0.390 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.610 0.390 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.609 0.391 0.000
C61 Malignant neoplasm of prostate
0.609 0.391 0.000
M94 Other disorders of cartilage
0.609 0.391 0.000
W29 Contact with other powered hand tools and household machinery
0.606 0.393 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.606 0.394 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.606 0.394 0.000
S68.4 Traumatic amputation of hand at wrist level
0.606 0.394 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.606 0.394 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.606 0.394 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.606 0.394 0.000
S06.9 Intracranial injury, unspecified
0.605 0.395 0.000
S06.8 Other intracranial injuries
0.605 0.395 0.000
S06.7 Intracranial injury with prolonged coma
0.605 0.395 0.000
S06.4 Epidural haemorrhage
0.605 0.395 0.000
S06.3 Focal brain injury
0.605 0.395 0.000
S06.2 Diffuse brain injury
0.605 0.395 0.000
S06.1 Traumatic cerebral oedema
0.605 0.395 0.000
S06.0 Concussion
0.605 0.395 0.000
M06.8 Other specified rheumatoid arthritis
0.605 0.395 0.000
M06.4 Inflammatory polyarthropathy
0.605 0.395 0.000
M06.3 Rheumatoid nodule
0.605 0.395 0.000
M06.2 Rheumatoid bursitis
0.605 0.395 0.000
M06.1 Adult-onset Still's disease
0.605 0.395 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.604 0.395 0.000
T90 Sequelae of injuries of head
0.604 0.396 0.000
C79.2 Secondary malignant neoplasm of skin
0.604 0.396 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.604 0.396 0.000
S48 Traumatic amputation of shoulder and upper arm
0.604 0.396 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.604 0.396 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.604 0.396 0.000
S44 Injury of nerves at shoulder and upper arm level
0.604 0.396 0.000
S41 Open wound of shoulder and upper arm
0.604 0.396 0.000
S47 Crushing injury of shoulder and upper arm
0.604 0.396 0.000
G45.4 Transient global amnesia
0.603 0.397 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.601 0.399 0.000
C80 Malignant neoplasm without specification of site
0.601 0.399 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.601 0.399 0.000
F30-F39 Mood [affective] disorders
0.601 0.399 0.000
G96 Other disorders of central nervous system
0.600 0.400 0.000
T92 Sequelae of injuries of upper limb
0.599 0.401 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.599 0.401 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.599 0.401 0.000
J96 Respiratory failure, not elsewhere classified
0.599 0.401 0.000
Y44 Agents primarily affecting blood constituents
0.598 0.402 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.598 0.402 0.000
J98.1 Pulmonary collapse
0.598 0.402 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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