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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62355904
log Bayes Factor = 14.6667
Chromosome 5   position 56,056,471  (GRCh37) Explore rs62355904 on Ensembl!
Variant rs62355904 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
I25.1 Atherosclerotic heart disease
0.997 0.003 0.000
M54.59 Low back pain (Site unspecified)
0.995 0.005 0.000
I21.9 Acute myocardial infarction, unspecified
0.993 0.007 0.000
M20 Acquired deformities of fingers and toes
0.991 0.009 0.000
M54.56 Low back pain (Lumbar region)
0.991 0.009 0.000
I10-I15 Hypertensive diseases
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.983 0.017 0.000
I25.2 Old myocardial infarction
0.982 0.018 0.000
I10 Essential (primary) hypertension
0.974 0.026 0.000
M20.1 Hallux valgus (acquired)
0.973 0.027 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.960 0.040 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.944 0.056 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.938 0.062 0.000
I20 Angina pectoris
0.936 0.064 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.934 0.066 0.000
D69 Purpura and other haemorrhagic conditions
0.932 0.068 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.931 0.069 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.929 0.071 0.000
E70-E90 Metabolic disorders
0.928 0.072 0.000
E78.0 Pure hypercholesterolaemia
0.922 0.078 0.000
I77 Other disorders of arteries and arterioles
0.921 0.079 0.000
D68 Other coagulation defects
0.919 0.081 0.000
E78.5 Hyperlipidaemia, unspecified
0.916 0.084 0.000
D69.6 Thrombocytopenia, unspecified
0.914 0.086 0.000
M25 Other joint disorders, not elsewhere classified
0.912 0.088 0.000
S70-S79 Injuries to the hip and thigh
0.904 0.096 0.000
M45-M49 Spondylopathies
0.901 0.099 0.000
I71 Aortic aneurysm and dissection
0.885 0.115 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.880 0.120 0.000
S72 Fracture of femur
0.880 0.120 0.000
M24 Other specific joint derangements
0.879 0.121 0.000
I25.3 Aneurysm of heart
0.876 0.124 0.000
M05-M14 Inflammatory polyarthropathies
0.875 0.125 0.000
M35 Other systemic involvement of connective tissue
0.872 0.128 0.000
S00-S09 Injuries to the head
0.870 0.130 0.000
S72.0 Fracture of neck of femur
0.857 0.143 0.000
M31 Other necrotising vasculopathies
0.857 0.143 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.856 0.144 0.000
I22 Subsequent myocardial infarction
0.847 0.153 0.000
I72 Other aneurysm
0.846 0.154 0.000
I70 Atherosclerosis
0.845 0.155 0.000
Chapter XX External causes of morbidity and mortality
0.845 0.155 0.000
S72.00 Fracture of neck of femur (closed)
0.841 0.159 0.000
D68.2 Hereditary deficiency of other clotting factors
0.841 0.159 0.000
L40-L45 Papulosquamous disorders
0.836 0.164 0.000
I77.1 Stricture of artery
0.835 0.165 0.000
M81 Osteoporosis without pathological fracture
0.833 0.167 0.000
M20.4 Other hammer toe(s) (acquired)
0.832 0.168 0.000
M25.7 Osteophyte
0.829 0.171 0.000
M84 Disorders of continuity of bone
0.820 0.180 0.000
M54.57 Low back pain (Lumbosacral region)
0.820 0.180 0.000
I21.4 Acute subendocardial myocardial infarction
0.818 0.182 0.000
Chapter VI Diseases of the nervous system
0.818 0.182 0.000
M54.2 Cervicalgia
0.814 0.186 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.811 0.189 0.000
M86-M90 Other osteopathies
0.811 0.189 0.000
L40 Psoriasis
0.808 0.192 0.000
M35.3 Polymyalgia rheumatica
0.805 0.195 0.000
Chapter V Mental and behavioural disorders
0.801 0.199 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.798 0.202 0.000
I20.9 Angina pectoris, unspecified
0.795 0.205 0.000
M20.5 Other deformities of toe(s) (acquired)
0.790 0.210 0.000
M34 Systemic sclerosis
0.787 0.213 0.000
I25.5 Ischaemic cardiomyopathy
0.786 0.214 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.786 0.214 0.000
I12 Hypertensive renal disease
0.785 0.215 0.000
S06 Intracranial injury
0.785 0.215 0.000
M70-M79 Other soft tissue disorders
0.784 0.216 0.000
I20.0 Unstable angina
0.783 0.217 0.000
S80-S89 Injuries to the knee and lower leg
0.781 0.219 0.000
M25.77 Osteophyte (Ankle and foot)
0.777 0.223 0.000
M24.1 Other articular cartilage disorders
0.774 0.226 0.000
I20.8 Other forms of angina pectoris
0.772 0.228 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.772 0.228 0.000
M13 Other arthritis
0.772 0.228 0.000
L40.9 Psoriasis, unspecified
0.772 0.228 0.000
M48 Other spondylopathies
0.771 0.229 0.000
M50 Cervical disk disorders
0.770 0.230 0.000
M21 Other acquired deformities of limbs
0.770 0.230 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.768 0.232 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.764 0.236 0.000
D68.6 Other Thrombophilia
0.763 0.237 0.000
M54.6 Pain in thoracic spine
0.763 0.237 0.000
M54.4 Lumbago with sciatica
0.762 0.238 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.760 0.240 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.758 0.242 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.756 0.244 0.000
M31.6 Other giant cell arteritis
0.754 0.246 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.752 0.248 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.750 0.250 0.000
M20.0 Deformity of finger(s)
0.750 0.250 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.744 0.256 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.744 0.256 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.743 0.257 0.000
E00-E07 Disorders of thyroid gland
0.742 0.258 0.000
I77.0 Arteriovenous fistula, acquired
0.741 0.259 0.000
M54.1 Radiculopathy
0.737 0.263 0.000
M53 Other dorsopathies, not elsewhere classified
0.736 0.264 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.733 0.267 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
D68.5 Primary Thrombophilia
0.729 0.271 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.729 0.271 0.000
W00-W19 Falls
0.726 0.274 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.726 0.274 0.000
M47 Spondylosis
0.724 0.276 0.000
M85 Other disorders of bone density and structure
0.721 0.279 0.000
D68.9 Coagulation defect, unspecified
0.719 0.281 0.000
M54.3 Sciatica
0.719 0.281 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.55 Low back pain (Thoracolumbar region)
0.717 0.283 0.000
M54.54 Low back pain-Thoracic
0.717 0.283 0.000
M54.53 Low back pain-Cervicothoracic
0.717 0.283 0.000
M54.52 Low back pain-Cervical
0.717 0.283 0.000
M54.51 Low back pain-Occipit-atl-axl
0.717 0.283 0.000
M54.50 Low back pain (Multiple sites in spine)
0.717 0.283 0.000
M54.8 Other dorsalgia
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M81.9 Osteoporosis, unspecified
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.716 0.284 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.713 0.287 0.000
M20.3 Other deformity of hallux (acquired)
0.711 0.289 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.711 0.289 0.000
I15 Secondary hypertension
0.707 0.292 0.000
I13 Hypertensive heart and renal disease
0.707 0.292 0.000
I11 Hypertensive heart disease
0.707 0.292 0.000
Chapter VIII Diseases of the ear and mastoid process
0.706 0.294 0.000
D80-D89 Certain disorders involving the immune mechanism
0.706 0.294 0.000
Chapter XXI Factors influencing health status and contact with health services
0.705 0.295 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.295 0.000
M07 Psoriatic and enteropathic arthropathies
0.703 0.297 0.000
S50-S59 Injuries to the elbow and forearm
0.701 0.299 0.000
E20-E35 Disorders of other endocrine glands
0.700 0.300 0.000
M13.9 Arthritis, unspecified
0.699 0.301 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.698 0.301 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.697 0.303 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.696 0.304 0.000
M35.7 Hypermobility syndrome
0.696 0.304 0.000
M80 Osteoporosis with pathological fracture
0.695 0.305 0.000
M25.8 Other specified joint disorders
0.695 0.305 0.000
I20.1 Angina pectoris with documented spasm
0.694 0.306 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.693 0.307 0.000
M25.3 Other instability of joint
0.693 0.307 0.000
E88 Other metabolic disorders
0.691 0.309 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.690 0.310 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.688 0.312 0.000
S01 Open wound of head
0.688 0.312 0.000
M79.6 Pain in limb
0.688 0.312 0.000
S72.4 Fracture of lower end of femur
0.687 0.313 0.000
M45 Ankylosing spondylitis
0.686 0.314 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.686 0.314 0.000
D67 Hereditary factor IX deficiency
0.685 0.315 0.000
D66 Hereditary factor VIII deficiency
0.685 0.315 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.685 0.315 0.000
S06.5 Traumatic subdural haemorrhage
0.685 0.315 0.000
I72.4 Aneurysm of artery of lower extremity
0.683 0.317 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.683 0.317 0.000
I84 Haemorrhoids
0.682 0.318 0.000
M25.4 Effusion of joint
0.682 0.318 0.000
M54.22 Cervicalgia (Cervical region)
0.681 0.319 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.319 0.000
S79 Other and unspecified injuries of hip and thigh
0.679 0.321 0.000
S00 Superficial injury of head
0.678 0.322 0.000
M83 Adult osteomalacia
0.677 0.323 0.000
M82 Osteoporosis in diseases classified elsewhere
0.677 0.323 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.676 0.324 0.000
S05 Injury of eye and orbit
0.676 0.324 0.000
S80 Superficial injury of lower leg
0.675 0.325 0.000
M24.0 Loose body in joint
0.674 0.326 0.000
M20.2 Hallux rigidus
0.673 0.327 0.000
M81.4 Drug-induced osteoporosis
0.670 0.329 0.000
G56 Mononeuropathies of upper limb
0.670 0.330 0.000
T33-T35 Frostbite
0.670 0.330 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.670 0.330 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.670 0.330 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.670 0.330 0.000
T00-T07 Injuries involving multiple body regions
0.670 0.330 0.000
S10-S19 Injuries to the neck
0.670 0.330 0.000
I72.0 Aneurysm of carotid artery
0.669 0.331 0.000
S72.3 Fracture of shaft of femur
0.669 0.331 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.668 0.332 0.000
I70.0 Atherosclerosis of aorta
0.668 0.332 0.000
D69.9 Haemorrhagic condition, unspecified
0.668 0.332 0.000
D69.8 Other specified haemorrhagic conditions
0.668 0.332 0.000
D69.5 Secondary thrombocytopenia
0.668 0.332 0.000
D69.4 Other primary thrombocytopenia
0.668 0.332 0.000
D69.2 Other nonthrombocytopenic purpura
0.668 0.332 0.000
D69.1 Qualitative platelet defects
0.668 0.332 0.000
D69.0 Allergic purpura
0.668 0.332 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.668 0.332 0.000
E78.8 Other disorders of lipoprotein metabolism
0.668 0.332 0.000
E78.6 Lipoprotein deficiency
0.668 0.332 0.000
E78.4 Other hyperlipidaemia
0.668 0.332 0.000
E78.3 Hyperchylomicronaemia
0.668 0.332 0.000
E78.1 Pure hyperglyceridaemia
0.668 0.332 0.000
I22.8 Subsequent myocardial infarction of other sites
0.667 0.333 0.000
I24 Other acute ischaemic heart diseases
0.665 0.335 0.000
E85 Amyloidosis
0.665 0.335 0.000
E84 Cystic fibrosis
0.665 0.335 0.000
E79 Disorders of purine and pyrimidine metabolism
0.665 0.335 0.000
E77 Disorders of glycoprotein metabolism
0.665 0.335 0.000
E76 Disorders of glycosaminoglycan metabolism
0.665 0.335 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.665 0.335 0.000
E74 Other disorders of carbohydrate metabolism
0.665 0.335 0.000
E73 Lactose intolerance
0.665 0.335 0.000
E72 Other disorders of amino-acid metabolism
0.665 0.335 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.665 0.335 0.000
E70 Disorders of aromatic amino-acid metabolism
0.665 0.335 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.665 0.335 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.664 0.336 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.664 0.336 0.000
M46 Other inflammatory spondylopathies
0.664 0.336 0.000
M06 Other rheumatoid arthritis
0.664 0.336 0.000
M48.0 Spinal stenosis
0.663 0.337 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.663 0.337 0.000
E40-E46 Malnutrition
0.662 0.338 0.000
I77.8 Other specified disorders of arteries and arterioles
0.660 0.339 0.000
I77.5 Necrosis of artery
0.660 0.339 0.000
I77.4 Coeliac artery compression syndrome
0.660 0.339 0.000
I77.3 Arterial fibromuscular dysplasia
0.660 0.339 0.000
I77.2 Rupture of artery
0.660 0.339 0.000
D68.4 Acquired coagulation factor deficiency
0.659 0.341 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.659 0.341 0.000
D68.1 Hereditary factor XI deficiency
0.659 0.341 0.000
D68.0 Von Willebrand's disease
0.659 0.341 0.000
E78.2 Mixed hyperlipidaemia
0.657 0.343 0.000
D68.8 Other specified coagulation defects
0.657 0.343 0.000
M87 Osteonecrosis
0.655 0.345 0.000
M25.72 Osteophyte (Upper arm)
0.654 0.346 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.654 0.346 0.000
M25.9 Joint disorder, unspecified
0.654 0.346 0.000
M25.2 Flail joint
0.654 0.346 0.000
M25.1 Fistula of joint
0.654 0.346 0.000
M25.0 Haemarthrosis
0.654 0.346 0.000
I72.8 Aneurysm of other specified arteries
0.651 0.349 0.000
S09 Other and unspecified injuries of head
0.651 0.349 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.651 0.349 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.650 0.350 0.000
S78 Traumatic amputation of hip and thigh
0.648 0.352 0.000
S77 Crushing injury of hip and thigh
0.648 0.352 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.648 0.352 0.000
S75 Injury of blood vessels at hip and thigh level
0.648 0.352 0.000
S74 Injury of nerves at hip and thigh level
0.648 0.352 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.648 0.352 0.000
S71 Open wound of hip and thigh
0.648 0.352 0.000
S70 Superficial injury of hip and thigh
0.648 0.352 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.648 0.352 0.000
S90-S99 Injuries to the ankle and foot
0.648 0.352 0.000
M49 Spondylopathies in diseases classified elsewhere
0.646 0.354 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.645 0.354 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.645 0.355 0.000
I74 Arterial embolism and thrombosis
0.645 0.355 0.000
I78 Diseases of capillaries
0.642 0.358 0.000
S06.3 Focal brain injury
0.641 0.359 0.000
X60-X84 Intentional self-harm
0.640 0.359 0.000
L40.5 Arthropathic psoriasis
0.639 0.361 0.000
M05 Seropositive rheumatoid arthritis
0.637 0.363 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.637 0.363 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.637 0.363 0.000
V10-V19 Pedal cyclist injured in transport accident
0.636 0.364 0.000
M34.9 Systemic sclerosis, unspecified
0.635 0.365 0.000
M50.2 Other cervical disk displacement
0.635 0.365 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.635 0.365 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.635 0.365 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.635 0.365 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.635 0.365 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.635 0.365 0.000
I71.0 Dissection of aorta [any part]
0.635 0.365 0.000
V20-V29 Motorcycle rider injured in transport accident
0.634 0.366 0.000
E50-E64 Other nutritional deficiencies
0.634 0.366 0.000
G30-G32 Other degenerative diseases of the nervous system
0.634 0.366 0.000
M51 Other intervertebral disk disorders
0.633 0.366 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.632 0.368 0.000
S72.9 Fracture of femur, part unspecified
0.631 0.369 0.000
S72.8 Fractures of other parts of femur
0.631 0.369 0.000
S72.7 Multiple fractures of femur
0.631 0.369 0.000
S72.2 Subtrochanteric fracture
0.631 0.369 0.000
L10-L14 Bullous disorders
0.631 0.369 0.000
L40.0 Psoriasis vulgaris
0.631 0.369 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.630 0.370 0.000
M24.9 Joint derangement, unspecified
0.630 0.370 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.630 0.370 0.000
M24.7 Protrusio acetabuli
0.630 0.370 0.000
M24.6 Ankylosis of joint
0.630 0.370 0.000
M24.5 Contracture of joint
0.630 0.370 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.630 0.370 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.630 0.370 0.000
M24.2 Disorder of ligament
0.630 0.370 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.630 0.370 0.000
M47.8 Other spondylosis
0.629 0.371 0.000
I12.0 Hypertensive renal disease with renal failure
0.628 0.372 0.000
I85 Oesophageal varices
0.628 0.372 0.000
M14 Arthropathies in other diseases classified elsewhere
0.627 0.373 0.000
M12 Other specific arthropathies
0.627 0.373 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.627 0.373 0.000
M08 Juvenile arthritis
0.627 0.373 0.000
M79.7 Fibromyalgia
0.627 0.373 0.000
I77.6 Arteritis, unspecified
0.626 0.374 0.000
L20-L30 Dermatitis and eczema
0.626 0.374 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.625 0.375 0.000
M35.8 Other specified systemic involvement of connective tissue
0.625 0.375 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.625 0.375 0.000
M35.5 Multifocal fibrosclerosis
0.625 0.375 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.625 0.375 0.000
M35.2 Behcet's disease
0.625 0.375 0.000
M35.1 Other overlap syndromes
0.625 0.375 0.000
O36 Maternal care for other known or suspected foetal problems
0.624 0.376 0.000
S08 Traumatic amputation of part of head
0.624 0.376 0.000
S07 Crushing injury of head
0.624 0.376 0.000
S04 Injury of cranial nerves
0.624 0.376 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.624 0.376 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.623 0.377 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.622 0.377 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.621 0.379 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.621 0.379 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.619 0.381 0.000
M23 Internal derangement of knee
0.619 0.381 0.000
M90 Osteopathies in diseases classified elsewhere
0.618 0.381 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.618 0.382 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.618 0.382 0.000
M79.62 Pain in limb (Upper arm)
0.617 0.383 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.616 0.384 0.000
S72.01 Fracture of neck of femur (open)
0.615 0.385 0.000
M31.9 Necrotising vasculopathy, unspecified
0.614 0.386 0.000
M31.8 Other specified necrotising vasculopathies
0.614 0.386 0.000
M31.7 Microscopic polyangiitis
0.614 0.386 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.614 0.386 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.614 0.386 0.000
M31.3 Wegener's granulomatosis
0.614 0.386 0.000
M31.2 Lethal midline granuloma
0.614 0.386 0.000
M31.1 Thrombotic microangiopathy
0.614 0.386 0.000
M31.0 Hypersensitivity angiitis
0.614 0.386 0.000
S01.0 Open wound of scalp
0.614 0.386 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.613 0.387 0.000
F10.0 Acute intoxication
0.613 0.387 0.000
M25.78 Osteophyte (Other)
0.612 0.388 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.612 0.388 0.000
G58 Other mononeuropathies
0.611 0.389 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.610 0.389 0.000
F10.3 Withdrawal state
0.610 0.390 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.607 0.393 0.000
I72.9 Aneurysm of unspecified site
0.607 0.393 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.607 0.393 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.607 0.393 0.000
I72.3 Aneurysm of iliac artery
0.607 0.393 0.000
I72.2 Aneurysm of renal artery
0.607 0.393 0.000
I72.1 Aneurysm of artery of upper extremity
0.607 0.393 0.000
I70.9 Generalised and unspecified atherosclerosis
0.606 0.394 0.000
I70.8 Atherosclerosis of other arteries
0.606 0.394 0.000
I70.1 Atherosclerosis of renal artery
0.606 0.394 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.606 0.394 0.000
Y35-Y36 Legal intervention and operations of war
0.606 0.394 0.000
Y10-Y34 Event of undetermined intent
0.606 0.394 0.000
Y00-Y09 Assault
0.606 0.394 0.000
X85-X99 Assault
0.606 0.394 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.606 0.394 0.000
X50-X57 Overexertion, travel and privation
0.606 0.394 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.606 0.394 0.000
X30-X39 Exposure to forces of nature
0.606 0.394 0.000
X20-X29 Contact with venomous animals and plants
0.606 0.394 0.000
X10-X19 Contact with heat and hot substances
0.606 0.394 0.000
X00-X09 Exposure to smoke, fire and flames
0.606 0.394 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.606 0.394 0.000
W75-W84 Other accidental threats to breathing
0.606 0.394 0.000
W65-W74 Accidental drowning and submersion
0.606 0.394 0.000
W50-W64 Exposure to animate mechanical forces
0.606 0.394 0.000
V98-V99 Other and unspecified transport accidents
0.606 0.394 0.000
V95-V97 Air and space transport accidents
0.606 0.394 0.000
V90-V94 Water transport accidents
0.606 0.394 0.000
V80-V89 Other land transport accidents
0.606 0.394 0.000
V70-V79 Bus occupant injured in transport accident
0.606 0.394 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.606 0.394 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.606 0.394 0.000
V40-V49 Car occupant injured in transport accident
0.606 0.394 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.606 0.394 0.000
V01-V09 Pedestrian injured in transport accident
0.606 0.394 0.000
W20-W49 Exposure to inanimate mechanical forces
0.606 0.394 0.000
M84.0 Malunion of fracture
0.603 0.396 0.000
T92 Sequelae of injuries of upper limb
0.600 0.399 0.000
T17 Foreign body in respiratory tract
0.600 0.400 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.600 0.400 0.000
L80 Vitiligo
0.600 0.400 0.000
L44 Other papulosquamous disorders
0.599 0.401 0.000
L41 Parapsoriasis
0.599 0.401 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.599 0.401 0.000
L42 Pityriasis rosea
0.599 0.401 0.000
Z95.0 Presence of cardiac pacemaker
0.599 0.401 0.000
E03 Other hypothyroidism
0.599 0.401 0.000
F80-F89 Disorders of psychological development
0.599 0.401 0.000
Y52 Agents primarily affecting the cardiovascular system
0.598 0.402 0.000
F99-F99 Unspecified mental disorder
0.597 0.403 0.000
M81.8 Other osteoporosis
0.597 0.403 0.000
M81.6 Localised osteoporosis [Lequesne]
0.597 0.403 0.000
M81.5 Idiopathic osteoporosis
0.597 0.403 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.597 0.403 0.000
M81.2 Osteoporosis of disuse
0.597 0.403 0.000
M81.1 Postoophorectomy osteoporosis
0.597 0.403 0.000
M81.0 Postmenopausal osteoporosis
0.597 0.403 0.000
I84.1 Internal haemorrhoids with other complications
0.597 0.403 0.000
S72.1 Pertrochanteric fracture
0.597 0.403 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.597 0.403 0.000
M25.71 Osteophyte (Shoulder region)
0.596 0.404 0.000
S06.2 Diffuse brain injury
0.596 0.404 0.000
M48.02 Spinal stenosis (Cervical region)
0.595 0.405 0.000
S60-S69 Injuries to the wrist and hand
0.595 0.405 0.000
M25.79 Osteophyte (Site unspecified)
0.595 0.405 0.000
M25.73 Osteophyte (Forearm)
0.595 0.405 0.000
M25.70 Osteophyte (Multiple sites)
0.595 0.405 0.000
S40-S49 Injuries to the shoulder and upper arm
0.594 0.406 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.594 0.406 0.000
G40-G47 Episodic and paroxysmal disorders
0.594 0.406 0.000
M79.1 Myalgia
0.594 0.406 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.593 0.407 0.000
M11 Other crystal arthropathies
0.592 0.407 0.000
G54 Nerve root and plexus disorders
0.592 0.408 0.000
W07 Fall involving chair
0.591 0.409 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.591 0.409 0.000
M21.3 Wrist or foot drop (acquired)
0.590 0.410 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.589 0.411 0.000
M84.9 Disorder of continuity of bone, unspecified
0.588 0.412 0.000
M84.8 Other disorders of continuity of bone
0.588 0.412 0.000
M84.4 Pathological fracture, not elsewhere classified
0.588 0.412 0.000
M84.3 Stress fracture, not elsewhere classified
0.588 0.412 0.000
M84.2 Delayed union of fracture
0.588 0.412 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.588 0.412 0.000
M50.0 Cervical disk disorder with myelopathy
0.587 0.413 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.587 0.413 0.000
T18 Foreign body in alimentary tract
0.586 0.413 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.585 0.415 0.000
S00.8 Superficial injury of other parts of head
0.585 0.415 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.585 0.415 0.000
M88 Paget's disease of bone [osteitis deformans]
0.584 0.416 0.000
M79.60 Pain in limb (Multiple sites)
0.584 0.416 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.584 0.416 0.000
M47.2 Other spondylosis with radiculopathy
0.584 0.416 0.000
M54.29 Cervicalgia-Site unspe
0.584 0.416 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.584 0.416 0.000
M54.27 Cervicalgia-Lumbosacral
0.584 0.416 0.000
M54.26 Cervicalgia-Lumbar
0.584 0.416 0.000
M54.25 Cervicalgia-Thoracolumbar
0.584 0.416 0.000
M54.24 Cervicalgia-Thoracic
0.584 0.416 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.584 0.416 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.584 0.416 0.000
M54.20 Cervicalgia-Mult site
0.584 0.416 0.000
Z85 Personal history of malignant neoplasm
0.582 0.418 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.581 0.419 0.000
M86 Osteomyelitis
0.581 0.419 0.000
M07.3 Other psoriatic arthropathies
0.580 0.420 0.000
I12.9 Hypertensive renal disease without renal failure
0.580 0.420 0.000
L40.8 Other psoriasis
0.579 0.421 0.000
L40.4 Guttate psoriasis
0.579 0.421 0.000
L40.3 Pustulosis palmaris et plantaris
0.579 0.421 0.000
L40.2 Acrodermatitis continua
0.579 0.421 0.000
L40.1 Generalised pustular psoriasis
0.579 0.421 0.000
L85 Other epidermal thickening
0.578 0.422 0.000
S80.8 Other superficial injuries of lower leg
0.578 0.422 0.000
E07 Other disorders of thyroid
0.577 0.423 0.000
M79.8 Other specified soft tissue disorders
0.577 0.423 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.577 0.423 0.000
G56.0 Carpal tunnel syndrome
0.575 0.425 0.000
I30-I52 Other forms of heart disease
0.575 0.425 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.574 0.426 0.000
F70-F79 Mental retardation
0.574 0.426 0.000
F60-F69 Disorders of adult personality and behaviour
0.574 0.426 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.574 0.426 0.000
M79.69 Pain in limb (Site unspecified)
0.574 0.426 0.000
Z98 Other postsurgical states
0.572 0.428 0.000
L91 Hypertrophic disorders of skin
0.572 0.428 0.000
G90-G99 Other disorders of the nervous system
0.572 0.428 0.000
Z90.7 Acquired absence of genital organ(s)
0.572 0.428 0.000
L43 Lichen planus
0.572 0.428 0.000
W19 Unspecified fall
0.571 0.429 0.000
I81 Portal vein thrombosis
0.571 0.429 0.000
M21.0 Valgus deformity, not elsewhere classified
0.570 0.430 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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