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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62366280
log Bayes Factor = 8.05999
Chromosome 5   position 60,849,318  (GRCh37) Explore rs62366280 on Ensembl!
Variant rs62366280 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
K22 Other diseases of oesophagus
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
G40-G47 Episodic and paroxysmal disorders
0.989 0.011 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.986 0.014 0.000
K86 Other diseases of pancreas
0.981 0.019 0.000
G40 Epilepsy
0.981 0.019 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.977 0.023 0.000
G40.9 Epilepsy, unspecified
0.973 0.027 0.000
C64-C68 Malignant neoplasms of urinary tract
0.971 0.029 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.971 0.029 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.970 0.030 0.000
C67 Malignant neoplasm of bladder
0.962 0.038 0.000
K22.4 Dyskinesia of oesophagus
0.959 0.041 0.000
C67.9 Bladder, unspecified
0.955 0.045 0.000
F30-F39 Mood [affective] disorders
0.953 0.047 0.000
K22.7 Barrett's oesophagus
0.952 0.048 0.000
C44 Other malignant neoplasms of skin
0.952 0.048 0.000
K29 Gastritis and duodenitis
0.949 0.051 0.000
K80 Cholelithiasis
0.944 0.056 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
K21 Gastro-oesophageal reflux disease
0.940 0.060 0.000
F60-F69 Disorders of adult personality and behaviour
0.940 0.060 0.000
K29.7 Gastritis, unspecified
0.939 0.061 0.000
M25 Other joint disorders, not elsewhere classified
0.938 0.062 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.935 0.065 0.000
M65-M68 Disorders of synovium and tendon
0.933 0.067 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.928 0.072 0.000
C44.5 Skin of trunk
0.924 0.076 0.000
K20 Oesophagitis
0.923 0.077 0.000
M24 Other specific joint derangements
0.923 0.077 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.922 0.078 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.918 0.082 0.000
C44.1 Skin of eyelid, including canthus
0.918 0.082 0.000
K86.1 Other chronic pancreatitis
0.917 0.083 0.000
M20 Acquired deformities of fingers and toes
0.916 0.084 0.000
K86.3 Pseudocyst of pancreas
0.913 0.087 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.908 0.092 0.000
F60 Specific personality disorders
0.907 0.093 0.000
M20.5 Other deformities of toe(s) (acquired)
0.903 0.097 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.899 0.101 0.000
K70-K77 Diseases of liver
0.898 0.102 0.000
M25.5 Pain in joint
0.896 0.104 0.000
M67 Other disorders of synovium and tendon
0.895 0.105 0.000
K85 Acute pancreatitis
0.890 0.110 0.000
F31 Bipolar affective disorder
0.885 0.115 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.885 0.115 0.000
C44.4 Skin of scalp and neck
0.882 0.118 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.881 0.119 0.000
S90-S99 Injuries to the ankle and foot
0.880 0.120 0.000
M25.57 Pain in joint (Ankle and foot)
0.877 0.123 0.000
S32 Fracture of lumbar spine and pelvis
0.871 0.129 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.869 0.131 0.000
M60-M63 Disorders of muscles
0.867 0.133 0.000
G20-G26 Extrapyramidal and movement disorders
0.861 0.139 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.861 0.139 0.000
S70-S79 Injuries to the hip and thigh
0.858 0.142 0.000
T23 Burn and corrosion of wrist and hand
0.857 0.143 0.000
F60.9 Personality disorder, unspecified
0.850 0.150 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.849 0.151 0.000
K22.2 Oesophageal obstruction
0.847 0.153 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.847 0.153 0.000
M67.8 Other specified disorders of synovium and tendon
0.847 0.153 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.846 0.154 0.000
K29.0 Acute haemorrhagic gastritis
0.846 0.154 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.844 0.156 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.844 0.156 0.000
M31 Other necrotising vasculopathies
0.842 0.158 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.840 0.160 0.000
K85.9 Acute pancreatitis, unspecified
0.834 0.166 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.834 0.166 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.830 0.170 0.000
M22 Disorders of patella
0.829 0.171 0.000
F30 Manic episode
0.829 0.171 0.000
Chapter I Certain infectious and parasitic diseases
0.828 0.172 0.000
L82 Seborrhoeic keratosis
0.826 0.174 0.000
G40.8 Other epilepsy
0.825 0.175 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.825 0.175 0.000
Chapter X Diseases of the respiratory system
0.824 0.176 0.000
S32.0 Fracture of lumbar vertebra
0.821 0.179 0.000
L50-L54 Urticaria and erythema
0.819 0.180 0.000
G43 Migraine
0.818 0.182 0.000
K29.2 Alcoholic gastritis
0.818 0.182 0.000
G90-G99 Other disorders of the nervous system
0.817 0.183 0.000
S10-S19 Injuries to the neck
0.817 0.183 0.000
C71 Malignant neoplasm of brain
0.815 0.185 0.000
C50-C50 Malignant neoplasm of breast
0.814 0.186 0.000
K86.8 Other specified diseases of pancreas
0.812 0.188 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.811 0.189 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.806 0.194 0.000
M91-M94 Chondropathies
0.806 0.194 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.805 0.195 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.802 0.197 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.801 0.198 0.000
F60.3 Emotionally unstable personality disorder
0.801 0.199 0.000
K22.9 Disease of oesophagus, unspecified
0.800 0.200 0.000
C32 Malignant neoplasm of larynx
0.799 0.201 0.000
K26 Duodenal ulcer
0.798 0.202 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.797 0.203 0.000
M25.4 Effusion of joint
0.796 0.204 0.000
K76 Other diseases of liver
0.796 0.204 0.000
G25 Other extrapyramidal and movement disorders
0.795 0.205 0.000
K80.8 Other cholelithiasis
0.794 0.206 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.792 0.208 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.786 0.214 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
K22.8 Other specified diseases of oesophagus
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.782 0.218 0.000
J40-J47 Chronic lower respiratory diseases
0.782 0.218 0.000
G62 Other polyneuropathies
0.781 0.219 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.781 0.219 0.000
G40.5 Special epileptic syndromes
0.780 0.220 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.779 0.221 0.000
M62 Other disorders of muscle
0.778 0.222 0.000
D45 Polycythaemia vera
0.778 0.222 0.000
S00-S09 Injuries to the head
0.775 0.225 0.000
G70-G73 Diseases of myoneural junction and muscle
0.774 0.226 0.000
J44 Other chronic obstructive pulmonary disease
0.773 0.227 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.772 0.228 0.000
M24.2 Disorder of ligament
0.772 0.228 0.000
K81 Cholecystitis
0.770 0.230 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.767 0.233 0.000
M80-M85 Disorders of bone density and structure
0.766 0.234 0.000
K82 Other diseases of gallbladder
0.764 0.236 0.000
M24.1 Other articular cartilage disorders
0.763 0.237 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.761 0.239 0.000
T40.4 Other synthetic narcotics
0.760 0.240 0.000
M24.0 Loose body in joint
0.759 0.240 0.000
G41 Status epilepticus
0.758 0.242 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.758 0.242 0.000
F80-F89 Disorders of psychological development
0.756 0.244 0.000
K73 Chronic hepatitis, not elsewhere classified
0.756 0.244 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.754 0.246 0.000
M33 Dermatopolymyositis
0.753 0.247 0.000
C34 Malignant neoplasm of bronchus and lung
0.753 0.247 0.000
S91 Open wound of ankle and foot
0.752 0.248 0.000
L20-L30 Dermatitis and eczema
0.750 0.250 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
F32 Depressive episode
0.747 0.253 0.000
D00-D09 In situ neoplasms
0.747 0.253 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.746 0.254 0.000
D46 Myelodysplastic syndromes
0.746 0.254 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.744 0.256 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.742 0.258 0.000
S01 Open wound of head
0.742 0.258 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.740 0.260 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.740 0.260 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.740 0.260 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.739 0.261 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.738 0.262 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.737 0.263 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.735 0.265 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.735 0.265 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.734 0.265 0.000
Q00-Q07 Congenital malformations of the nervous system
0.734 0.265 0.000
M31.6 Other giant cell arteritis
0.734 0.266 0.000
M25.3 Other instability of joint
0.733 0.267 0.000
D47.1 Chronic myeloproliferative disease
0.733 0.267 0.000
M25.9 Joint disorder, unspecified
0.733 0.267 0.000
B15-B19 Viral hepatitis
0.732 0.268 0.000
A30-A49 Other bacterial diseases
0.731 0.269 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.731 0.269 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.730 0.270 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.728 0.272 0.000
D37.7 Other digestive organs
0.728 0.272 0.000
F43 Reaction to severe stress, and adjustment disorders
0.728 0.272 0.000
M30 Polyarteritis nodosa and related conditions
0.726 0.274 0.000
S90 Superficial injury of ankle and foot
0.726 0.274 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.724 0.276 0.000
C66 Malignant neoplasm of ureter
0.723 0.277 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.723 0.277 0.000
C44.2 Skin of ear and external auricular canal
0.723 0.277 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.722 0.277 0.000
M25.52 Pain in joint (Upper arm)
0.722 0.278 0.000
K86.9 Disease of pancreas, unspecified
0.721 0.279 0.000
S72 Fracture of femur
0.721 0.279 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.718 0.281 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.718 0.282 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.718 0.282 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.716 0.284 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C67.6 Ureteric orifice
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.285 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.715 0.285 0.000
K29.3 Chronic superficial gastritis
0.714 0.286 0.000
K22.3 Perforation of oesophagus
0.713 0.287 0.000
C67.4 Posterior wall of bladder
0.713 0.287 0.000
M22.8 Other disorders of patella
0.712 0.288 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.712 0.288 0.000
M67.4 Ganglion
0.711 0.289 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.710 0.290 0.000
K74 Fibrosis and cirrhosis of liver
0.710 0.290 0.000
M25.0 Haemarthrosis
0.710 0.290 0.000
K27 Peptic ulcer, site unspecified
0.709 0.291 0.000
M25.53 Pain in joint (Forearm)
0.709 0.291 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.709 0.291 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.292 0.000
M32 Systemic lupus erythematosus
0.707 0.292 0.000
K22.5 Diverticulum of oesophagus, acquired
0.707 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.706 0.294 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.703 0.297 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.703 0.297 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.703 0.297 0.000
T23.3 Burn of third degree of wrist and hand
0.703 0.297 0.000
Q80-Q89 Other congenital malformations
0.702 0.297 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.701 0.299 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.701 0.299 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.701 0.299 0.000
G47 Sleep disorders
0.699 0.301 0.000
Q66 Congenital deformities of feet
0.698 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
G62.9 Polyneuropathy, unspecified
0.697 0.303 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.696 0.304 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.696 0.304 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.696 0.304 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
T36 Poisoning by systemic antibiotics
0.696 0.304 0.000
C44.6 Skin of upper limb, including shoulder
0.696 0.304 0.000
F44 Dissociative [conversion] disorders
0.695 0.305 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.694 0.306 0.000
K81.9 Cholecystitis, unspecified
0.694 0.306 0.000
D37.9 Digestive organ, unspecified
0.694 0.306 0.000
K72 Hepatic failure, not elsewhere classified
0.693 0.307 0.000
K26.7 Chronic without haemorrhage or perforation
0.693 0.307 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.693 0.307 0.000
C45 Mesothelioma
0.692 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
F45 Somatoform disorders
0.691 0.309 0.000
C65 Malignant neoplasm of renal pelvis
0.691 0.309 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.691 0.309 0.000
D37.0 Lip, oral cavity and pharynx
0.690 0.310 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.690 0.310 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.690 0.310 0.000
M00-M03 Infectious arthropathies
0.690 0.310 0.000
C67.8 Overlapping lesion of bladder
0.689 0.310 0.000
C67.7 Urachus
0.689 0.310 0.000
C67.5 Bladder neck
0.689 0.310 0.000
C67.3 Anterior wall of bladder
0.689 0.310 0.000
C67.0 Trigone of bladder
0.689 0.310 0.000
D80-D89 Certain disorders involving the immune mechanism
0.689 0.311 0.000
M25.51 Pain in joint (Shoulder region)
0.688 0.312 0.000
F33 Recurrent depressive disorder
0.687 0.313 0.000
D41.4 Bladder
0.685 0.315 0.000
S32.4 Fracture of acetabulum
0.685 0.315 0.000
Q76 Congenital malformations of spine and bony thorax
0.685 0.315 0.000
M22.4 Chondromalacia patellae
0.685 0.315 0.000
J43 Emphysema
0.684 0.316 0.000
G61 Inflammatory polyneuropathy
0.684 0.316 0.000
F38 Other mood [affective] disorders
0.683 0.317 0.000
F34 Persistent mood [affective] disorders
0.683 0.317 0.000
F39 Unspecified mood [affective] disorder
0.683 0.317 0.000
S50-S59 Injuries to the elbow and forearm
0.683 0.317 0.000
M40-M43 Deforming dorsopathies
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.683 0.317 0.000
G60 Hereditary and idiopathic neuropathy
0.683 0.317 0.000
L53 Other erythematous conditions
0.683 0.317 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.683 0.317 0.000
C67.1 Dome of bladder
0.682 0.317 0.000
C44.8 Overlapping lesion of skin
0.682 0.318 0.000
L91 Hypertrophic disorders of skin
0.682 0.318 0.000
C50 Malignant neoplasm of breast
0.681 0.319 0.000
M62.8 Other specified disorders of muscle
0.680 0.320 0.000
K29.9 Gastroduodenitis, unspecified
0.680 0.320 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.680 0.320 0.000
S01.0 Open wound of scalp
0.679 0.321 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.679 0.321 0.000
M50-M54 Other dorsopathies
0.678 0.322 0.000
C71.1 Frontal lobe
0.678 0.322 0.000
T88.4 Failed or difficult intubation
0.677 0.323 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.677 0.323 0.000
S72.1 Pertrochanteric fracture
0.677 0.323 0.000
D04 Carcinoma in situ of skin
0.677 0.323 0.000
K80.3 Calculus of bile duct with cholangitis
0.677 0.323 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
D37.4 Colon
0.676 0.324 0.000
S70 Superficial injury of hip and thigh
0.675 0.325 0.000
J60-J70 Lung diseases due to external agents
0.675 0.325 0.000
F30.2 Mania with psychotic symptoms
0.674 0.326 0.000
F68 Other disorders of adult personality and behaviour
0.674 0.326 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.674 0.326 0.000
F65 Disorders of sexual preference
0.674 0.326 0.000
F64 Gender identity disorders
0.674 0.326 0.000
F63 Habit and impulse disorders
0.674 0.326 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.674 0.326 0.000
F69 Unspecified disorder of adult personality and behaviour
0.674 0.326 0.000
F61 Mixed and other personality disorders
0.674 0.326 0.000
F42 Obsessive-compulsive disorder
0.673 0.327 0.000
M25.2 Flail joint
0.673 0.327 0.000
M25.1 Fistula of joint
0.673 0.327 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.672 0.327 0.000
S20-S29 Injuries to the thorax
0.672 0.328 0.000
F30.0 Hypomania
0.671 0.329 0.000
Chapter XX External causes of morbidity and mortality
0.671 0.329 0.000
F31.9 Bipolar affective disorder, unspecified
0.671 0.329 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.671 0.329 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.671 0.329 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.671 0.329 0.000
T25 Burn and corrosion of ankle and foot
0.671 0.329 0.000
T21 Burn and corrosion of trunk
0.671 0.329 0.000
T20 Burn and corrosion of head and neck
0.671 0.329 0.000
M67.1 Other contracture of tendon (sheath)
0.670 0.330 0.000
M25.58 Pain in joint (Other)
0.670 0.330 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.670 0.330 0.000
F99-F99 Unspecified mental disorder
0.670 0.330 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.669 0.331 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.667 0.333 0.000
C32.0 Glottis
0.667 0.333 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.667 0.333 0.000
T23.2 Burn of second degree of wrist and hand
0.667 0.333 0.000
M25.47 Effusion of joint (Ankle and foot)
0.667 0.333 0.000
S05 Injury of eye and orbit
0.667 0.333 0.000
G95 Other diseases of spinal cord
0.667 0.333 0.000
T31 Burns classified according to extent of body surface involved
0.666 0.334 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.664 0.336 0.000
J84 Other interstitial pulmonary diseases
0.663 0.337 0.000
M24.9 Joint derangement, unspecified
0.662 0.338 0.000
M24.7 Protrusio acetabuli
0.662 0.338 0.000
M24.6 Ankylosis of joint
0.662 0.338 0.000
M24.5 Contracture of joint
0.662 0.338 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.662 0.338 0.000
L52 Erythema nodosum
0.662 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.661 0.339 0.000
S37 Injury of urinary and pelvic organs
0.661 0.339 0.000
S36 Injury of intra-abdominal organs
0.661 0.339 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.661 0.339 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.661 0.339 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.661 0.339 0.000
S31 Open wound of abdomen, lower back and pelvis
0.661 0.339 0.000
M24.26 Disorder of ligament (Lower leg)
0.661 0.339 0.000
G30-G32 Other degenerative diseases of the nervous system
0.660 0.340 0.000
C71.9 Brain, unspecified
0.660 0.340 0.000
K75 Other inflammatory liver diseases
0.660 0.340 0.000
C43 Malignant melanoma of skin
0.660 0.340 0.000
C32.1 Supraglottis
0.659 0.341 0.000
L10-L14 Bullous disorders
0.658 0.341 0.000
S42 Fracture of shoulder and upper arm
0.658 0.342 0.000
M35 Other systemic involvement of connective tissue
0.658 0.342 0.000
M65 Synovitis and tenosynovitis
0.657 0.343 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.657 0.343 0.000
C67.2 Lateral wall of bladder
0.657 0.343 0.000
B35-B49 Mycoses
0.656 0.344 0.000
C34.9 Bronchus or lung, unspecified
0.656 0.344 0.000
M66 Spontaneous rupture of synovium and tendon
0.655 0.345 0.000
K73.9 Chronic hepatitis, unspecified
0.654 0.346 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.653 0.346 0.000
K29.5 Chronic gastritis, unspecified
0.653 0.347 0.000
K26.5 Chronic or unspecified with perforation
0.652 0.348 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.651 0.349 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.651 0.349 0.000
C31 Malignant neoplasm of accessory sinuses
0.651 0.349 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.651 0.349 0.000
C37 Malignant neoplasm of thymus
0.651 0.349 0.000
C33 Malignant neoplasm of trachea
0.651 0.349 0.000
G46.7 Other lacunar syndromes
0.651 0.349 0.000
G24 Dystonia
0.650 0.349 0.000
F60.8 Other specific personality disorders
0.650 0.350 0.000
F60.7 Dependent personality disorder
0.650 0.350 0.000
F60.6 Anxious [avoidant] personality disorder
0.650 0.350 0.000
F60.5 Anankastic personality disorder
0.650 0.350 0.000
F60.4 Histrionic personality disorder
0.650 0.350 0.000
F60.2 Dissocial personality disorder
0.650 0.350 0.000
F60.1 Schizoid personality disorder
0.650 0.350 0.000
F60.0 Paranoid personality disorder
0.650 0.350 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.650 0.350 0.000
J95-J99 Other diseases of the respiratory system
0.650 0.350 0.000
G91 Hydrocephalus
0.650 0.350 0.000
M20.3 Other deformity of hallux (acquired)
0.649 0.350 0.000
S32.1 Fracture of sacrum
0.649 0.351 0.000
S12 Fracture of neck
0.649 0.351 0.000
F32.1 Moderate depressive episode
0.648 0.352 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.647 0.353 0.000
L83 Acanthosis nigricans
0.647 0.353 0.000
S72.10 Pertrochanteric fracture (closed)
0.646 0.353 0.000
G43.9 Migraine, unspecified
0.645 0.355 0.000
Q38.7 Pharyngeal pouch
0.645 0.355 0.000
G64 Other disorders of peripheral nervous system
0.645 0.355 0.000
D48.0 Bone and articular cartilage
0.645 0.355 0.000
D48.5 Skin
0.645 0.355 0.000
L28 Lichen simplex chronicus and prurigo
0.644 0.356 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.644 0.356 0.000
K77 Liver disorders in diseases classified elsewhere
0.644 0.356 0.000
K71 Toxic liver disease
0.644 0.356 0.000
D60-D64 Aplastic and other anaemias
0.643 0.357 0.000
L50 Urticaria
0.643 0.357 0.000
M24.01 Loose body in joint (Shoulder region)
0.642 0.358 0.000
D41.0 Kidney
0.642 0.358 0.000
M21 Other acquired deformities of limbs
0.642 0.358 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.641 0.358 0.000
M67.3 Transient synovitis
0.641 0.358 0.000
M67.0 Short Achilles tendon (acquired)
0.641 0.358 0.000
M25.43 Effusion of joint (Forearm)
0.640 0.359 0.000
S92 Fracture of foot, except ankle
0.640 0.360 0.000
G43.1 Migraine with aura [classical migraine]
0.640 0.360 0.000
M70-M79 Other soft tissue disorders
0.640 0.360 0.000
C71.3 Parietal lobe
0.639 0.361 0.000
K76.6 Portal hypertension
0.639 0.361 0.000
G71 Primary disorders of muscles
0.638 0.362 0.000
K85.8 Other acute pancreatitis
0.638 0.362 0.000
K85.3 Drug-induced acute pancreatitis
0.638 0.362 0.000
K85.2 Alcohol-induced acute pancreatitis
0.638 0.362 0.000
K85.0 Idiopathic acute pancreatitis
0.638 0.362 0.000
S01.2 Open wound of nose
0.638 0.362 0.000
G44 Other headache syndromes
0.638 0.362 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.638 0.362 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.637 0.362 0.000
D86 Sarcoidosis
0.637 0.363 0.000
L85 Other epidermal thickening
0.636 0.363 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.635 0.365 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.635 0.365 0.000
M25.50 Pain in joint (Multiple sites)
0.635 0.365 0.000
A65-A69 Other spirochaetal diseases
0.634 0.365 0.000
F31.8 Other bipolar affective disorders
0.634 0.366 0.000
F31.7 Bipolar affective disorder, currently in remission
0.634 0.366 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.634 0.366 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.634 0.366 0.000
C70 Malignant neoplasm of meninges
0.634 0.366 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.634 0.366 0.000
T43.2 Other and unspecified antidepressants
0.633 0.367 0.000
G93 Other disorders of brain
0.632 0.368 0.000
L60-L75 Disorders of skin appendages
0.632 0.368 0.000
T43.9 Psychotropic drug, unspecified
0.632 0.368 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
T43.6 Psychostimulants with abuse potential
0.632 0.368 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.632 0.368 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.632 0.368 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.632 0.368 0.000
C71.8 Overlapping lesion of brain
0.631 0.369 0.000
S99 Other and unspecified injuries of ankle and foot
0.631 0.369 0.000
S98 Traumatic amputation of ankle and foot
0.631 0.369 0.000
S97 Crushing injury of ankle and foot
0.631 0.369 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.631 0.369 0.000
S95 Injury of blood vessels at ankle and foot level
0.631 0.369 0.000
S94 Injury of nerves at ankle and foot level
0.631 0.369 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.630 0.370 0.000
S32.3 Fracture of ilium
0.629 0.371 0.000
T42.4 Benzodiazepines
0.629 0.371 0.000
M20.0 Deformity of finger(s)
0.628 0.372 0.000
F30.9 Manic episode, unspecified
0.627 0.373 0.000
M92 Other juvenile osteochondrosis
0.626 0.374 0.000
M84 Disorders of continuity of bone
0.626 0.374 0.000
M20.1 Hallux valgus (acquired)
0.625 0.375 0.000
S32.2 Fracture of coccyx
0.624 0.375 0.000
L90 Atrophic disorders of skin
0.624 0.376 0.000
T18 Foreign body in alimentary tract
0.624 0.376 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.624 0.376 0.000
C50.2 Upper-inner quadrant of breast
0.624 0.376 0.000
D37.6 Liver, gallbladder and bile ducts
0.623 0.377 0.000
D37.3 Appendix
0.623 0.377 0.000
D37.2 Small intestine
0.623 0.377 0.000
K82.2 Perforation of gallbladder
0.622 0.378 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.622 0.378 0.000
M61 Calcification and ossification of muscle
0.622 0.378 0.000
M60 Myositis
0.622 0.378 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.620 0.380 0.000
T79-T79 Certain early complications of trauma
0.620 0.380 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.619 0.381 0.000
M50 Cervical disk disorders
0.619 0.381 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.618 0.382 0.000
C71.0 Cerebrum, except lobes and ventricles
0.618 0.382 0.000
D47.4 Osteomyelofibrosis
0.618 0.382 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.618 0.382 0.000
S91.0 Open wound of ankle
0.618 0.382 0.000
G23 Other degenerative diseases of basal ganglia
0.617 0.383 0.000
G21 Secondary Parkinsonism
0.617 0.383 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.617 0.383 0.000
G22 Parkinsonism in diseases classified elsewhere
0.617 0.383 0.000
F48 Other neurotic disorders
0.617 0.383 0.000
B15 Acute hepatitis A
0.617 0.383 0.000
C07 Malignant neoplasm of parotid gland
0.616 0.384 0.000
K29.4 Chronic atrophic gastritis
0.616 0.384 0.000
S78 Traumatic amputation of hip and thigh
0.615 0.385 0.000
S77 Crushing injury of hip and thigh
0.615 0.385 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.615 0.385 0.000
S75 Injury of blood vessels at hip and thigh level
0.615 0.385 0.000
S74 Injury of nerves at hip and thigh level
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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