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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62490898
log Bayes Factor = 22.0013
Chromosome 7   position 135,697,319  (GRCh37) Explore rs62490898 on Ensembl!
Variant rs62490898 is part of Cluster X0029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.996 0.004 0.000
N17-N19 Renal failure
0.995 0.005 0.000
K50-K52 Noninfective enteritis and colitis
0.994 0.006 0.000
E10 Insulin-dependent diabetes mellitus
0.993 0.007 0.000
M80-M85 Disorders of bone density and structure
0.988 0.012 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.987 0.013 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.985 0.015 0.000
E11 Non-insulin-dependent diabetes mellitus
0.977 0.023 0.000
I83 Varicose veins of lower extremities
0.977 0.023 0.000
K51 Ulcerative colitis
0.971 0.029 0.000
N19 Unspecified renal failure
0.969 0.031 0.000
N10-N16 Renal tubulo-interstitial diseases
0.968 0.032 0.000
Chapter VIII Diseases of the ear and mastoid process
0.966 0.034 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.965 0.035 0.000
Chapter XXI Factors influencing health status and contact with health services
0.964 0.036 0.000
Chapter I Certain infectious and parasitic diseases
0.964 0.036 0.000
I34 Nonrheumatic mitral valve disorders
0.963 0.037 0.000
Chapter VII Diseases of the eye and adnexa
0.961 0.039 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.960 0.040 0.000
Chapter XX External causes of morbidity and mortality
0.959 0.041 0.000
R20 Disturbances of skin sensation
0.959 0.041 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.955 0.045 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.955 0.045 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
E20-E35 Disorders of other endocrine glands
0.953 0.047 0.000
N13 Obstructive and reflux uropathy
0.948 0.052 0.000
K51.9 Ulcerative colitis, unspecified
0.946 0.054 0.000
I50 Heart failure
0.946 0.054 0.000
M45-M49 Spondylopathies
0.945 0.055 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.945 0.055 0.000
H30-H36 Disorders of choroid and retina
0.945 0.055 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.942 0.058 0.000
R21 Rash and other nonspecific skin eruption
0.942 0.058 0.000
I34.0 Mitral (valve) insufficiency
0.942 0.058 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.942 0.058 0.000
K50 Crohn's disease [regional enteritis]
0.941 0.059 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.941 0.059 0.000
M81 Osteoporosis without pathological fracture
0.940 0.060 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.934 0.066 0.000
M40-M43 Deforming dorsopathies
0.933 0.067 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.933 0.067 0.000
H65-H75 Diseases of middle ear and mastoid
0.932 0.068 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.931 0.069 0.000
I45 Other conduction disorders
0.928 0.072 0.000
K08 Other disorders of teeth and supporting structures
0.927 0.073 0.000
E11.3 With ophthalmic complications
0.926 0.074 0.000
Z51 Other medical care
0.926 0.074 0.000
Chapter II Neoplasms
0.923 0.077 0.000
G20-G26 Extrapyramidal and movement disorders
0.923 0.077 0.000
K90-K93 Other diseases of the digestive system
0.921 0.079 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
M81.9 Osteoporosis, unspecified
0.910 0.090 0.000
H36 Retinal disorders in diseases classified elsewhere
0.907 0.093 0.000
R00 Abnormalities of heart beat
0.905 0.095 0.000
N20-N23 Urolithiasis
0.903 0.097 0.000
R05 Cough
0.901 0.099 0.000
K92 Other diseases of digestive system
0.898 0.102 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.897 0.103 0.000
N18 Chronic renal failure
0.896 0.104 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.895 0.105 0.000
N60-N64 Disorders of breast
0.895 0.105 0.000
K02 Dental caries
0.895 0.105 0.000
K50.9 Crohn's disease, unspecified
0.891 0.109 0.000
N13.8 Other obstructive and reflux uropathy
0.890 0.110 0.000
G20 Parkinson's disease
0.888 0.112 0.000
M86-M90 Other osteopathies
0.888 0.112 0.000
R00.1 Bradycardia, unspecified
0.888 0.112 0.000
R79 Other abnormal findings of blood chemistry
0.887 0.113 0.000
H35 Other retinal disorders
0.886 0.114 0.000
E10.1 With ketoacidosis
0.884 0.116 0.000
N17 Acute renal failure
0.884 0.116 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.882 0.118 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.881 0.119 0.000
Z49 Care involving dialysis
0.881 0.119 0.000
H36.0 Diabetic retinopathy
0.881 0.119 0.000
M43 Other deforming dorsopathies
0.878 0.122 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.877 0.123 0.000
N40-N51 Diseases of male genital organs
0.875 0.125 0.000
D00-D09 In situ neoplasms
0.873 0.127 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.871 0.129 0.000
M85 Other disorders of bone density and structure
0.870 0.130 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.870 0.130 0.000
E87.2 Acidosis
0.868 0.132 0.000
N25-N29 Other disorders of kidney and ureter
0.868 0.132 0.000
E88 Other metabolic disorders
0.867 0.133 0.000
I51 Complications and ill-defined descriptions of heart disease
0.866 0.134 0.000
Chapter V Mental and behavioural disorders
0.866 0.134 0.000
Z50 Care involving use of rehabilitation procedures
0.864 0.136 0.000
E10.3 With ophthalmic complications
0.862 0.138 0.000
E23 Hypofunction and other disorders of pituitary gland
0.862 0.138 0.000
H65 Nonsuppurative otitis media
0.861 0.139 0.000
E11.5 With peripheral circulatory complications
0.860 0.140 0.000
C15-C26 Malignant neoplasms of digestive organs
0.858 0.142 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.857 0.143 0.000
N00-N08 Glomerular diseases
0.856 0.144 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.856 0.144 0.000
B07 Viral warts
0.855 0.145 0.000
S40-S49 Injuries to the shoulder and upper arm
0.854 0.146 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.853 0.146 0.000
E78.5 Hyperlipidaemia, unspecified
0.853 0.147 0.000
E10.0 With coma
0.852 0.148 0.000
H53-H54 Visual disturbances and blindness
0.851 0.149 0.000
M48 Other spondylopathies
0.851 0.149 0.000
E27 Other disorders of adrenal gland
0.850 0.150 0.000
N60 Benign mammary dysplasia
0.850 0.150 0.000
Z45 Adjustment and management of implanted device
0.850 0.150 0.000
K65-K67 Diseases of peritoneum
0.849 0.151 0.000
K40-K46 Hernia
0.847 0.153 0.000
R50-R69 General symptoms and signs
0.846 0.154 0.000
M80 Osteoporosis with pathological fracture
0.844 0.156 0.000
Z92 Personal history of medical treatment
0.844 0.156 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.842 0.158 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.842 0.158 0.000
I42 Cardiomyopathy
0.842 0.158 0.000
K92.0 Haematemesis
0.841 0.159 0.000
D60-D64 Aplastic and other anaemias
0.840 0.160 0.000
D04 Carcinoma in situ of skin
0.839 0.161 0.000
I74 Arterial embolism and thrombosis
0.837 0.163 0.000
Z51.1 Chemotherapy session for neoplasm
0.836 0.164 0.000
I05-I09 Chronic rheumatic heart diseases
0.836 0.164 0.000
E86 Volume depletion
0.836 0.164 0.000
R56 Convulsions, not elsewhere classified
0.835 0.165 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.835 0.165 0.000
Q60-Q64 Congenital malformations of the urinary system
0.834 0.166 0.000
C71 Malignant neoplasm of brain
0.833 0.167 0.000
K02.9 Dental caries, unspecified
0.831 0.169 0.000
I46 Cardiac arrest
0.831 0.169 0.000
M45 Ankylosing spondylitis
0.831 0.169 0.000
B02 Zoster [herpes zoster]
0.830 0.170 0.000
I87 Other disorders of veins
0.830 0.170 0.000
N21 Calculus of lower urinary tract
0.829 0.171 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.829 0.171 0.000
A30-A49 Other bacterial diseases
0.828 0.172 0.000
Z51.2 Other chemotherapy
0.828 0.172 0.000
Z92.3 Personal history of irradiation
0.828 0.172 0.000
R56.8 Other and unspecified convulsions
0.828 0.172 0.000
I50.9 Heart failure, unspecified
0.826 0.174 0.000
Z51.5 Palliative care
0.825 0.175 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.825 0.175 0.000
M43.1 Spondylolisthesis
0.824 0.176 0.000
M05-M14 Inflammatory polyarthropathies
0.824 0.176 0.000
E11.2 With renal complications
0.822 0.178 0.000
E10.4 With neurological complications
0.821 0.179 0.000
K51.2 Ulcerative (chronic) proctitis
0.821 0.179 0.000
K35-K38 Diseases of appendix
0.818 0.182 0.000
E50-E64 Other nutritional deficiencies
0.817 0.183 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.814 0.186 0.000
C60-C63 Malignant neoplasms of male genital organs
0.813 0.187 0.000
E10.5 With peripheral circulatory complications
0.813 0.187 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.812 0.188 0.000
G90-G99 Other disorders of the nervous system
0.812 0.188 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.812 0.188 0.000
S43.0 Dislocation of shoulder joint
0.812 0.188 0.000
R02 Gangrene, not elsewhere classified
0.809 0.191 0.000
M84 Disorders of continuity of bone
0.809 0.191 0.000
M89 Other disorders of bone
0.809 0.191 0.000
E10.9 Without complications
0.807 0.192 0.000
I50.1 Left ventricular failure
0.806 0.194 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.804 0.196 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.804 0.196 0.000
N18.9 Chronic renal failure, unspecified
0.802 0.198 0.000
E10.2 With renal complications
0.801 0.199 0.000
I45.1 Other and unspecified right bundle-branch block
0.801 0.199 0.000
H35.8 Other specified retinal disorders
0.800 0.200 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.798 0.202 0.000
E28 Ovarian dysfunction
0.798 0.202 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.797 0.203 0.000
Z50.5 Speech therapy
0.797 0.203 0.000
C15 Malignant neoplasm of oesophagus
0.797 0.203 0.000
H34 Retinal vascular occlusions
0.796 0.204 0.000
I72 Other aneurysm
0.794 0.206 0.000
E11.1 With ketoacidosis
0.794 0.206 0.000
K05 Gingivitis and periodontal diseases
0.794 0.206 0.000
N18.0 End-stage renal disease
0.794 0.206 0.000
N61 Inflammatory disorders of breast
0.792 0.208 0.000
K51.5 Mucosal proctocolitis
0.792 0.208 0.000
G25 Other extrapyramidal and movement disorders
0.790 0.210 0.000
Y52 Agents primarily affecting the cardiovascular system
0.790 0.210 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.789 0.211 0.000
E87.7 Fluid overload
0.789 0.211 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.788 0.212 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.788 0.212 0.000
M91-M94 Chondropathies
0.787 0.213 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.787 0.213 0.000
I50.0 Congestive heart failure
0.786 0.214 0.000
E87.5 Hyperkalaemia
0.786 0.214 0.000
C16 Malignant neoplasm of stomach
0.785 0.215 0.000
R63 Symptoms and signs concerning food and fluid intake
0.783 0.217 0.000
M48.0 Spinal stenosis
0.782 0.218 0.000
E27.8 Other specified disorders of adrenal gland
0.782 0.218 0.000
W00-W19 Falls
0.781 0.219 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.781 0.219 0.000
R61 Hyperhidrosis
0.781 0.219 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.778 0.222 0.000
N21.0 Calculus in bladder
0.776 0.224 0.000
H66 Suppurative and unspecified otitis media
0.776 0.224 0.000
K82 Other diseases of gallbladder
0.776 0.224 0.000
N41 Inflammatory diseases of prostate
0.776 0.224 0.000
E11.4 With neurological complications
0.775 0.224 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.775 0.225 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.775 0.225 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.774 0.226 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.773 0.227 0.000
K41 Femoral hernia
0.772 0.228 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.770 0.230 0.000
C71.9 Brain, unspecified
0.769 0.231 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.769 0.231 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
A41 Other septicaemia
0.766 0.234 0.000
M00-M03 Infectious arthropathies
0.765 0.234 0.000
H43-H45 Disorders of vitreous body and globe
0.765 0.235 0.000
Z51.8 Other specified medical care
0.765 0.235 0.000
N20 Calculus of kidney and ureter
0.763 0.237 0.000
K10 Other diseases of jaws
0.763 0.237 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.762 0.238 0.000
R94 Abnormal results of function studies
0.761 0.238 0.000
W20-W49 Exposure to inanimate mechanical forces
0.761 0.239 0.000
D04.6 Skin of upper limb, including shoulder
0.761 0.239 0.000
I45.6 Preexcitation syndrome
0.760 0.240 0.000
X20-X29 Contact with venomous animals and plants
0.760 0.240 0.000
R90.0 Intracranial space-occupying lesion
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.758 0.242 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.758 0.242 0.000
I36 Nonrheumatic tricuspid valve disorders
0.758 0.242 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.757 0.243 0.000
B02.9 Zoster without complication
0.756 0.244 0.000
Z51.9 Medical care, unspecified
0.755 0.245 0.000
N50 Other disorders of male genital organs
0.754 0.246 0.000
M85.8 Other specified disorders of bone density and structure
0.753 0.247 0.000
R20.2 Paraesthesia of skin
0.753 0.247 0.000
H35.3 Degeneration of macula and posterior pole
0.752 0.248 0.000
A00-A09 Intestinal infectious diseases
0.752 0.248 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.751 0.249 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.751 0.249 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.751 0.249 0.000
I45.8 Other specified conduction disorders
0.750 0.250 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.749 0.251 0.000
E83 Disorders of mineral metabolism
0.748 0.252 0.000
R29.6 Tendency to fall, not elsewhere classified
0.748 0.252 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.748 0.252 0.000
I81 Portal vein thrombosis
0.748 0.252 0.000
Z49.0 Preparatory care for dialysis
0.746 0.254 0.000
R00.2 Palpitations
0.746 0.254 0.000
K65 Peritonitis
0.746 0.254 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.745 0.255 0.000
N60.0 Solitary cyst of breast
0.745 0.255 0.000
H80-H83 Diseases of inner ear
0.745 0.255 0.000
N17.9 Acute renal failure, unspecified
0.745 0.255 0.000
N60.4 Mammary duct ectasia
0.743 0.257 0.000
K13 Other diseases of lip and oral mucosa
0.743 0.257 0.000
B15-B19 Viral hepatitis
0.742 0.258 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.742 0.258 0.000
N17.0 Acute renal failure with tubular necrosis
0.740 0.260 0.000
N60.3 Fibrosclerosis of breast
0.739 0.261 0.000
E13 Other specified diabetes mellitus
0.738 0.262 0.000
E23.7 Disorder of pituitary gland, unspecified
0.738 0.262 0.000
N48 Other disorders of penis
0.736 0.264 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.735 0.265 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.735 0.265 0.000
E40-E46 Malnutrition
0.734 0.266 0.000
K52 Other non-infective gastro-enteritis and colitis
0.734 0.266 0.000
Q61 Cystic kidney disease
0.733 0.267 0.000
K50.0 Crohn's disease of small intestine
0.732 0.268 0.000
Z49.1 Extracorporeal dialysis
0.732 0.268 0.000
I30 Acute pericarditis
0.732 0.268 0.000
Z53.8 Procedure not carried out for other reasons
0.732 0.268 0.000
I80 Phlebitis and thrombophlebitis
0.731 0.269 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.731 0.269 0.000
H72 Perforation of tympanic membrane
0.730 0.270 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.730 0.270 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.730 0.270 0.000
M48.06 Spinal stenosis (Lumbar region)
0.730 0.270 0.000
E78.2 Mixed hyperlipidaemia
0.729 0.271 0.000
I33 Acute and subacute endocarditis
0.727 0.273 0.000
M89.9 Disorder of bone, unspecified
0.725 0.275 0.000
H74 Other disorders of middle ear and mastoid
0.724 0.276 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.724 0.276 0.000
H53 Visual disturbances
0.724 0.276 0.000
M40 Kyphosis and lordosis
0.724 0.276 0.000
N11 Chronic tubulo-interstitial nephritis
0.723 0.276 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.723 0.277 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.723 0.277 0.000
K02.8 Other dental caries
0.722 0.278 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.722 0.278 0.000
N99-N99 Other disorders of the genitourinary system
0.722 0.278 0.000
G62 Other polyneuropathies
0.722 0.278 0.000
E87.0 Hyperosmolality and hypernatraemia
0.722 0.278 0.000
R87 Abnormal findings in specimens from female genital organs
0.721 0.279 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.720 0.280 0.000
N13.6 Pyonephrosis
0.720 0.280 0.000
D04.7 Skin of lower limb, including hip
0.719 0.281 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.719 0.281 0.000
I86 Varicose veins of other sites
0.719 0.281 0.000
H60-H62 Diseases of external ear
0.719 0.281 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.718 0.282 0.000
V40-V49 Car occupant injured in transport accident
0.718 0.282 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.284 0.000
I48 Atrial fibrillation and flutter
0.715 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.284 0.000
I40 Acute myocarditis
0.715 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.284 0.000
I37 Pulmonary valve disorders
0.715 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.284 0.000
Z94 Transplanted organ and tissue status
0.715 0.285 0.000
Z92.0 Personal history of contraception
0.715 0.285 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.715 0.285 0.000
Z49.2 Other dialysis
0.714 0.285 0.000
Q50-Q56 Congenital malformations of genital organs
0.714 0.286 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E73 Lactose intolerance
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
D64 Other anaemias
0.714 0.286 0.000
K82.8 Other specified diseases of gallbladder
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
E29 Testicular dysfunction
0.713 0.287 0.000
E10.8 With unspecified complications
0.712 0.288 0.000
E10.7 With multiple complications
0.712 0.288 0.000
E10.6 With other specified complications
0.712 0.288 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.712 0.288 0.000
G90 Disorders of autonomic nervous system
0.712 0.288 0.000
C15.5 Lower third of oesophagus
0.712 0.288 0.000
Z54 Convalescence
0.711 0.289 0.000
I73 Other peripheral vascular diseases
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
K43 Ventral hernia
0.710 0.290 0.000
I51.7 Cardiomegaly
0.710 0.290 0.000
N20.1 Calculus of ureter
0.710 0.290 0.000
E23.0 Hypopituitarism
0.710 0.290 0.000
N03 Chronic nephritic syndrome
0.710 0.290 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.710 0.290 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.710 0.290 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.709 0.290 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.709 0.291 0.000
M47 Spondylosis
0.709 0.291 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.709 0.291 0.000
M83 Adult osteomalacia
0.708 0.292 0.000
M82 Osteoporosis in diseases classified elsewhere
0.708 0.292 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.708 0.292 0.000
I88 Nonspecific lymphadenitis
0.708 0.292 0.000
H65.3 Chronic mucoid otitis media
0.708 0.292 0.000
K92.1 Melaena
0.707 0.293 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.707 0.293 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.706 0.294 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.706 0.294 0.000
C71.1 Frontal lobe
0.706 0.294 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.296 0.000
I49 Other cardiac arrhythmias
0.703 0.297 0.000
H69 Other disorders of Eustachian tube
0.702 0.298 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.702 0.298 0.000
H54 Blindness and low vision
0.702 0.298 0.000
I44 Atrioventricular and left bundle-branch block
0.702 0.298 0.000
D06 Carcinoma in situ of cervix uteri
0.701 0.299 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.701 0.299 0.000
S20-S29 Injuries to the thorax
0.701 0.299 0.000
E11.8 With unspecified complications
0.700 0.300 0.000
E11.7 With multiple complications
0.700 0.300 0.000
E11.6 With other specified complications
0.700 0.300 0.000
E11.0 With coma
0.700 0.300 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.700 0.300 0.000
R73 Elevated blood glucose level
0.700 0.300 0.000
D55-D59 Haemolytic anaemias
0.699 0.301 0.000
I42.0 Dilated cardiomyopathy
0.699 0.301 0.000
K50.8 Other Crohn's disease
0.699 0.301 0.000
M43.0 Spondylolysis
0.699 0.301 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.699 0.301 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.698 0.301 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.698 0.302 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.698 0.302 0.000
I82 Other venous embolism and thrombosis
0.697 0.303 0.000
H90-H95 Other disorders of ear
0.697 0.303 0.000
K51.4 Pseudopolyposis of colon
0.697 0.303 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.696 0.304 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.695 0.305 0.000
S43.1 Dislocation of acromioclavicular joint
0.695 0.305 0.000
N41.1 Chronic prostatitis
0.694 0.306 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.694 0.306 0.000
N15 Other renal tubulo-interstitial diseases
0.694 0.306 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.694 0.306 0.000
M85.0 Fibrous dysplasia (monostotic)
0.693 0.307 0.000
I45.5 Other specified heart block
0.693 0.307 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.692 0.308 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.692 0.308 0.000
I85 Oesophageal varices
0.692 0.308 0.000
Z45.2 Adjustment and management of vascular access device
0.691 0.309 0.000
B00 Herpesviral [herpes simplex] infections
0.691 0.309 0.000
I71 Aortic aneurysm and dissection
0.691 0.309 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.691 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
A75-A79 Rickettsioses
0.691 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.309 0.000
A65-A69 Other spirochaetal diseases
0.691 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.309 0.000
A15-A19 Tuberculosis
0.691 0.309 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.691 0.309 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.691 0.309 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.691 0.309 0.000
D80-D89 Certain disorders involving the immune mechanism
0.690 0.309 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.690 0.310 0.000
D04.4 Skin of scalp and neck
0.690 0.310 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.690 0.310 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
I51.9 Heart disease, unspecified
0.689 0.311 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.689 0.311 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.689 0.311 0.000
H73 Other disorders of tympanic membrane
0.689 0.311 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.689 0.311 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.312 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.312 0.000
Y10-Y34 Event of undetermined intent
0.687 0.312 0.000
Y00-Y09 Assault
0.687 0.312 0.000
X85-X99 Assault
0.687 0.312 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.312 0.000
X50-X57 Overexertion, travel and privation
0.687 0.312 0.000
X30-X39 Exposure to forces of nature
0.687 0.312 0.000
X10-X19 Contact with heat and hot substances
0.687 0.312 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.312 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.312 0.000
W75-W84 Other accidental threats to breathing
0.687 0.312 0.000
W65-W74 Accidental drowning and submersion
0.687 0.312 0.000
W50-W64 Exposure to animate mechanical forces
0.687 0.312 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.312 0.000
V95-V97 Air and space transport accidents
0.687 0.312 0.000
V90-V94 Water transport accidents
0.687 0.312 0.000
V80-V89 Other land transport accidents
0.687 0.312 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.312 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.312 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.312 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.312 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.312 0.000
R20.3 Hyperaesthesia
0.687 0.313 0.000
R20.1 Hypoaesthesia of skin
0.687 0.313 0.000
R20.0 Anaesthesia of skin
0.687 0.313 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.687 0.313 0.000
E28.2 Polycystic ovarian syndrome
0.687 0.313 0.000
I42.9 Cardiomyopathy, unspecified
0.686 0.314 0.000
K08.3 Retained dental root
0.686 0.314 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.686 0.314 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.686 0.314 0.000
I51.4 Myocarditis, unspecified
0.685 0.315 0.000
Q80-Q89 Other congenital malformations
0.685 0.315 0.000
K03 Other diseases of hard tissues of teeth
0.685 0.315 0.000
K00 Disorders of tooth development and eruption
0.685 0.315 0.000
I72.4 Aneurysm of artery of lower extremity
0.685 0.315 0.000
I74.5 Embolism and thrombosis of iliac artery
0.684 0.315 0.000
R27 Other lack of coordination
0.684 0.316 0.000
R61.0 Localised hyperhidrosis
0.684 0.316 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.684 0.316 0.000
R76 Other abnormal immunological findings in serum
0.684 0.316 0.000
C16.0 Cardia
0.684 0.316 0.000
I05 Rheumatic mitral valve diseases
0.683 0.316 0.000
M13 Other arthritis
0.683 0.317 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.317 0.000
E34 Other endocrine disorders
0.683 0.317 0.000
E32 Diseases of thymus
0.683 0.317 0.000
E31 Polyglandular dysfunction
0.683 0.317 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.317 0.000
E26 Hyperaldosteronism
0.683 0.317 0.000
E25 Adrenogenital disorders
0.683 0.317 0.000
E24 Cushing's syndrome
0.683 0.317 0.000
E20 Hypoparathyroidism
0.683 0.317 0.000
X60-X84 Intentional self-harm
0.682 0.318 0.000
C61 Malignant neoplasm of prostate
0.682 0.318 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.681 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.681 0.319 0.000
C64-C68 Malignant neoplasms of urinary tract
0.681 0.319 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.680 0.320 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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