TreeWAS – Variant ID: rs6457617

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
J33 Nasal polyp	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M06.3 Rheumatoid nodule	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
M06.0 Seronegative rheumatoid arthritis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
J33.0 Polyp of nasal cavity	1.000	0.000	0.000
J32 Chronic sinusitis	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
J32.9 Chronic sinusitis, unspecified	0.999	0.001	0.000
E10.3 With ophthalmic complications	0.999	0.001	0.000
L40-L45 Papulosquamous disorders	0.999	0.001	0.000
M45-M49 Spondylopathies	0.999	0.001	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
M31 Other necrotising vasculopathies	0.999	0.001	0.000
M65-M68 Disorders of synovium and tendon	0.998	0.002	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.998	0.002	0.000
E11 Non-insulin-dependent diabetes mellitus	0.998	0.002	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.998	0.002	0.000
M65 Synovitis and tenosynovitis	0.997	0.003	0.000
E78.0 Pure hypercholesterolaemia	0.996	0.004	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.996	0.004	0.000
E11.9 Without complications	0.995	0.005	0.000
I20-I25 Ischaemic heart diseases	0.995	0.005	0.000
Chapter IX Diseases of the circulatory system	0.994	0.006	0.000
M06.34 Rheumatoid nodule (Hand)	0.994	0.006	0.000
Chapter II Neoplasms	0.992	0.008	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.991	0.009	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.989	0.011	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.988	0.012	0.000
C44 Other malignant neoplasms of skin	0.987	0.013	0.000
M31.6 Other giant cell arteritis	0.987	0.013	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.987	0.013	0.000
I25 Chronic ischaemic heart disease	0.985	0.015	0.000
L40.5 Arthropathic psoriasis	0.985	0.015	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.984	0.016	0.000
C44.7 Skin of lower limb, including hip	0.983	0.017	0.000
I25.1 Atherosclerotic heart disease	0.983	0.017	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.982	0.018	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.982	0.018	0.000
J45.9 Asthma, unspecified	0.981	0.019	0.000
C44.3 Skin of other and unspecified parts of face	0.979	0.021	0.000
I21 Acute myocardial infarction	0.978	0.022	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.978	0.022	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.975	0.025	0.000
M31.3 Wegener's granulomatosis	0.974	0.026	0.000
I22 Subsequent myocardial infarction	0.974	0.026	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.974	0.026	0.000
E10.5 With peripheral circulatory complications	0.973	0.027	0.000
M34 Systemic sclerosis	0.968	0.032	0.000
I25.5 Ischaemic cardiomyopathy	0.966	0.034	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.965	0.035	0.000
E10.1 With ketoacidosis	0.965	0.035	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.964	0.036	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.964	0.036	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.963	0.037	0.000
E11.3 With ophthalmic complications	0.961	0.039	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.956	0.044	0.000
J35 Chronic diseases of tonsils and adenoids	0.954	0.046	0.000
C09 Malignant neoplasm of tonsil	0.953	0.047	0.000
I10-I15 Hypertensive diseases	0.947	0.053	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.946	0.054	0.000
E70-E90 Metabolic disorders	0.946	0.054	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.946	0.054	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.945	0.055	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.945	0.055	0.000
I10 Essential (primary) hypertension	0.944	0.056	0.000
M25 Other joint disorders, not elsewhere classified	0.942	0.058	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.941	0.059	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.938	0.062	0.000
Chapter XX External causes of morbidity and mortality	0.937	0.063	0.000
L57.0 Actinic keratosis	0.934	0.066	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.934	0.066	0.000
D00-D09 In situ neoplasms	0.928	0.072	0.000
E10.4 With neurological complications	0.927	0.073	0.000
M25.4 Effusion of joint	0.926	0.074	0.000
E06 Thyroiditis	0.926	0.074	0.000
J20-J22 Other acute lower respiratory infections	0.924	0.076	0.000
J45 Asthma	0.920	0.080	0.000
D06 Carcinoma in situ of cervix uteri	0.919	0.081	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.915	0.085	0.000
D06.9 Cervix, unspecified	0.912	0.088	0.000
C09.9 Tonsil, unspecified	0.909	0.091	0.000
J40-J47 Chronic lower respiratory diseases	0.906	0.094	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.904	0.096	0.000
M34.9 Systemic sclerosis, unspecified	0.902	0.098	0.000
J35.1 Hypertrophy of tonsils	0.901	0.099	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.900	0.100	0.000
E10.6 With other specified complications	0.900	0.100	0.000
M25.40 Effusion of joint (Multiple sites)	0.899	0.101	0.000
M06.4 Inflammatory polyarthropathy	0.899	0.101	0.000
E06.3 Autoimmune thyroiditis	0.898	0.102	0.000
M25.3 Other instability of joint	0.891	0.109	0.000
E10.8 With unspecified complications	0.886	0.114	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.886	0.114	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.885	0.115	0.000
C44.0 Skin of lip	0.882	0.118	0.000
M07 Psoriatic and enteropathic arthropathies	0.881	0.119	0.000
M30 Polyarteritis nodosa and related conditions	0.881	0.119	0.000
C82.0 Small cleaved cell, follicular	0.879	0.121	0.000
J22 Unspecified acute lower respiratory infection	0.878	0.122	0.000
Y57 Other and unspecified drugs and medicaments	0.878	0.122	0.000
Y00-Y09 Assault	0.875	0.125	0.000
C02.2 Ventral surface of tongue	0.875	0.125	0.000
J33.8 Other polyp of sinus	0.875	0.125	0.000
C44.1 Skin of eyelid, including canthus	0.873	0.127	0.000
J32.1 Chronic frontal sinusitis	0.870	0.130	0.000
Y57.9 Drug or medicament, unspecified	0.870	0.130	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.868	0.132	0.000
I21.9 Acute myocardial infarction, unspecified	0.867	0.133	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.866	0.134	0.000
M05.8 Other seropositive rheumatoid arthritis	0.865	0.135	0.000
M25.46 Effusion of joint (Lower leg)	0.863	0.137	0.000
J95-J99 Other diseases of the respiratory system	0.863	0.137	0.000
C73 Malignant neoplasm of thyroid gland	0.862	0.138	0.000
I60-I69 Cerebrovascular diseases	0.862	0.138	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.859	0.141	0.000
X60-X84 Intentional self-harm	0.856	0.144	0.000
E11.1 With ketoacidosis	0.855	0.145	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.855	0.145	0.000
E10.0 With coma	0.851	0.149	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.849	0.151	0.000
M25.47 Effusion of joint (Ankle and foot)	0.846	0.154	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.845	0.155	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.844	0.156	0.000
I61 Intracerebral haemorrhage	0.842	0.158	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.841	0.158	0.000
W50-W64 Exposure to animate mechanical forces	0.838	0.162	0.000
Y04 Assault by bodily force	0.837	0.163	0.000
M65.1 Other infective (teno)synovitis	0.835	0.165	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.834	0.166	0.000
L40.8 Other psoriasis	0.833	0.167	0.000
C02.1 Border of tongue	0.830	0.170	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.827	0.173	0.000
C10 Malignant neoplasm of oropharynx	0.826	0.174	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.826	0.174	0.000
E11.0 With coma	0.824	0.176	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.822	0.178	0.000
L10-L14 Bullous disorders	0.820	0.179	0.001
L42 Pityriasis rosea	0.821	0.179	0.000
J33.1 Polypoid sinus degeneration	0.820	0.179	0.000
L57.4 Cutis laxa senilis	0.820	0.180	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.818	0.182	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.816	0.184	0.000
M34.1 CR(E)ST syndrome	0.814	0.186	0.000
M66 Spontaneous rupture of synovium and tendon	0.813	0.187	0.000
M08 Juvenile arthritis	0.812	0.188	0.000
X50-X57 Overexertion, travel and privation	0.808	0.192	0.000
H36.0 Diabetic retinopathy	0.807	0.193	0.000
C02.4 Lingual tonsil	0.806	0.194	0.000
M07.3 Other psoriatic arthropathies	0.806	0.194	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.806	0.194	0.000
C03 Malignant neoplasm of gum	0.805	0.195	0.000
J32.3 Chronic sphenoidal sinusitis	0.802	0.198	0.000
M25.36 Other instability of joint (Lower leg)	0.802	0.198	0.000
M05.1 Rheumatoid lung disease	0.801	0.199	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.801	0.199	0.000
C69 Malignant neoplasm of eye and adnexa	0.800	0.200	0.000
J80 Adult respiratory distress syndrome	0.800	0.200	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.799	0.201	0.000
J35.0 Chronic tonsillitis	0.799	0.201	0.000
M34.8 Other forms of systemic sclerosis	0.798	0.202	0.000
Y49.2 Other and unspecified antidepressants	0.798	0.202	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.203	0.797
M25.8 Other specified joint disorders	0.797	0.203	0.000
M06.8 Other specified rheumatoid arthritis	0.796	0.203	0.000
C82.2 Large cell, follicular	0.796	0.204	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.796	0.204	0.000
M00-M03 Infectious arthropathies	0.796	0.204	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.796	0.204	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.796	0.204	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.795	0.204	0.000
M31.7 Microscopic polyangiitis	0.795	0.205	0.000
I05-I09 Chronic rheumatic heart diseases	0.795	0.205	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.794	0.206	0.000
I21.4 Acute subendocardial myocardial infarction	0.790	0.210	0.000
C82.4 Follicular lymphoma grade IIIb	0.790	0.210	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.788	0.212	0.000
Y10-Y34 Event of undetermined intent	0.787	0.213	0.000
M14 Arthropathies in other diseases classified elsewhere	0.785	0.215	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.784	0.216	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.784	0.216	0.000
C44.5 Skin of trunk	0.783	0.217	0.000
V10-V19 Pedal cyclist injured in transport accident	0.782	0.218	0.000
D86 Sarcoidosis	0.000	0.219	0.781
M25.34 Other instability of joint (Hand)	0.781	0.219	0.000
C13 Malignant neoplasm of hypopharynx	0.780	0.220	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.778	0.222	0.000
L40.4 Guttate psoriasis	0.778	0.222	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.777	0.223	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.776	0.224	0.000
L12 Pemphigoid	0.773	0.226	0.000
H36 Retinal disorders in diseases classified elsewhere	0.773	0.227	0.000
C82.3 Follicular lymphoma grade IIIa	0.773	0.227	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.772	0.228	0.000
Chapter VII Diseases of the eye and adnexa	0.772	0.228	0.000
I05 Rheumatic mitral valve diseases	0.771	0.229	0.000
E11.7 With multiple complications	0.769	0.231	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.768	0.232	0.000
Y04.8 Other specified place	0.765	0.234	0.000
C14.0 Pharynx, unspecified	0.765	0.235	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.764	0.236	0.000
V98-V99 Other and unspecified transport accidents	0.763	0.237	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.761	0.239	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.761	0.239	0.000
M05.2 Rheumatoid vasculitis	0.757	0.243	0.000
V20-V29 Motorcycle rider injured in transport accident	0.756	0.244	0.000
M12 Other specific arthropathies	0.756	0.244	0.000
E88 Other metabolic disorders	0.755	0.245	0.000
W75-W84 Other accidental threats to breathing	0.754	0.246	0.000
L40.1 Generalised pustular psoriasis	0.753	0.247	0.000
J84 Other interstitial pulmonary diseases	0.752	0.248	0.000
Y59 Other and unspecified vaccines and biological substances	0.752	0.248	0.000
E10.7 With multiple complications	0.751	0.249	0.000
C71 Malignant neoplasm of brain	0.751	0.249	0.000
H40-H42 Glaucoma	0.751	0.249	0.000
X51 Travel and motion	0.751	0.249	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.750	0.250	0.000
C12 Malignant neoplasm of pyriform sinus	0.749	0.251	0.000
M06.33 Rheumatoid nodule (Forearm)	0.749	0.251	0.000
H30-H36 Disorders of choroid and retina	0.749	0.251	0.000
I67 Other cerebrovascular diseases	0.748	0.252	0.000
M30.0 Polyarteritis nodosa	0.746	0.254	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.746	0.254	0.000
M13 Other arthritis	0.746	0.254	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.746	0.254	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.744	0.255	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.744	0.256	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.743	0.257	0.000
I23 Certain current complications following acute myocardial infarction	0.742	0.258	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.741	0.259	0.000
I67.1 Cerebral aneurysm, nonruptured	0.741	0.259	0.000
C09.0 Tonsillar fossa	0.740	0.260	0.000
Y04.2 School, other institution and public administrative area	0.739	0.261	0.000
Y58 Bacterial vaccines	0.738	0.262	0.000
M25.9 Joint disorder, unspecified	0.738	0.262	0.000
L41 Parapsoriasis	0.737	0.263	0.000
H40 Glaucoma	0.736	0.264	0.000
C07 Malignant neoplasm of parotid gland	0.732	0.268	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.732	0.268	0.000
J95.8 Other postprocedural respiratory disorders	0.731	0.269	0.000
H40.9 Glaucoma, unspecified	0.730	0.270	0.000
D80-D89 Certain disorders involving the immune mechanism	0.001	0.272	0.727
X10-X19 Contact with heat and hot substances	0.726	0.274	0.000
M35.2 Behcet's disease	0.724	0.276	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.723	0.277	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.722	0.278	0.000
E84 Cystic fibrosis	0.722	0.278	0.000
M66.3 Spontaneous rupture of flexor tendons	0.722	0.278	0.000
I13 Hypertensive heart and renal disease	0.721	0.279	0.000
L40.3 Pustulosis palmaris et plantaris	0.721	0.279	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.718	0.282	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.718	0.282	0.000
M06.1 Adult-onset Still's disease	0.718	0.282	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.718	0.282	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.717	0.283	0.000
M06.38 Rheumatoid nodule (Other)	0.717	0.283	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.717	0.283	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.717	0.283	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.717	0.283	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.717	0.283	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
L44 Other papulosquamous disorders	0.716	0.284	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.716	0.284	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.716	0.284	0.000
M31.2 Lethal midline granuloma	0.716	0.284	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.716	0.284	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.716	0.284	0.000
C74 Malignant neoplasm of adrenal gland	0.715	0.285	0.000
D86.0 Sarcoidosis of lung	0.000	0.286	0.714
M31.8 Other specified necrotising vasculopathies	0.714	0.286	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.713	0.287	0.000
M65.2 Calcific tendinitis	0.713	0.287	0.000
J85 Abscess of lung and mediastinum	0.713	0.287	0.000
V95-V97 Air and space transport accidents	0.711	0.289	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.711	0.289	0.000
E07 Other disorders of thyroid	0.710	0.290	0.000
I20 Angina pectoris	0.709	0.291	0.000
X00-X09 Exposure to smoke, fire and flames	0.709	0.291	0.000
C44.8 Overlapping lesion of skin	0.708	0.292	0.000
C10.9 Oropharynx, unspecified	0.708	0.292	0.000
D06.1 Exocervix	0.707	0.293	0.000
W55 Bitten or struck by other mammals	0.707	0.293	0.000
Y09 Assault by unspecified means	0.706	0.294	0.000
E03.8 Other specified hypothyroidism	0.706	0.294	0.000
I25.6 Silent myocardial ischaemia	0.706	0.294	0.000
I05.9 Mitral valve disease, unspecified	0.705	0.295	0.000
X51.9 Unspecified place	0.704	0.296	0.000
Y49.5 Other antipsychotics and neuroleptics	0.703	0.297	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.703	0.297	0.000
M22 Disorders of patella	0.703	0.297	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.702	0.298	0.000
C05 Malignant neoplasm of palate	0.701	0.299	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.299	0.700
C00 Malignant neoplasm of lip	0.700	0.300	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.699	0.301	0.000
V70-V79 Bus occupant injured in transport accident	0.697	0.303	0.000
L12.1 Cicatricial pemphigoid	0.696	0.303	0.000
V90-V94 Water transport accidents	0.696	0.304	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.694	0.306	0.000
M34.0 Progressive systemic sclerosis	0.694	0.306	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.694	0.306	0.000
M35.7 Hypermobility syndrome	0.694	0.306	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.694	0.306	0.000
J32.2 Chronic ethmoidal sinusitis	0.693	0.307	0.000
M65.0 Abscess of tendon sheath	0.693	0.307	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.692	0.307	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.692	0.307	0.000
J20 Acute bronchitis	0.692	0.308	0.000
C69.3 Choroid	0.692	0.308	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.692	0.308	0.000
C82.6 Cutaneous follicle centre lymphoma	0.691	0.308	0.000
C82.5 Diffuse follicle centre lymphoma	0.691	0.308	0.000
L55 Sunburn	0.691	0.309	0.000
C11 Malignant neoplasm of nasopharynx	0.691	0.309	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.690	0.310	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.687	0.313	0.000
M49 Spondylopathies in diseases classified elsewhere	0.686	0.313	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.686	0.314	0.000
C02.8 Overlapping lesion of tongue	0.685	0.315	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.685	0.315	0.000
C02.0 Dorsal surface of tongue	0.685	0.315	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.684	0.316	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.684	0.316	0.000
C83.3 Large cell (diffuse)	0.683	0.317	0.000
C09.8 Overlapping lesion of tonsil	0.683	0.317	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.683	0.317	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.683	0.317	0.000
I05.2 Mitral stenosis with insufficiency	0.683	0.317	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.682	0.318	0.000
E78.6 Lipoprotein deficiency	0.682	0.318	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.679	0.321	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.679	0.321	0.000
E77 Disorders of glycoprotein metabolism	0.678	0.321	0.000
E76 Disorders of glycosaminoglycan metabolism	0.678	0.321	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.678	0.321	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.678	0.321	0.000
E72 Other disorders of amino-acid metabolism	0.678	0.321	0.000
E65-E68 Obesity and other hyperalimentation	0.678	0.322	0.000
L57.3 Poikiloderma of Civatte	0.677	0.323	0.000
L57.2 Cutis rhomboidalis nuchae	0.677	0.323	0.000
L57.1 Actinic reticuloid	0.677	0.323	0.000
M08.0 Juvenile rheumatoid arthritis	0.677	0.323	0.000
M11 Other crystal arthropathies	0.676	0.324	0.000
M25.2 Flail joint	0.676	0.324	0.000
M25.1 Fistula of joint	0.676	0.324	0.000
L58 Radiodermatitis	0.675	0.324	0.000
M25.88 Other specified joint disorders (Other)	0.675	0.325	0.000
J32.4 Chronic pansinusitis	0.675	0.325	0.000
L57.5 Actinic granuloma	0.674	0.326	0.000
H40.5 Glaucoma secondary to other eye disorders	0.673	0.327	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.672	0.328	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.672	0.328	0.000
M13.8 Other specified arthritis	0.672	0.328	0.000
Y35-Y36 Legal intervention and operations of war	0.672	0.328	0.000
X85-X99 Assault	0.672	0.328	0.000
X30-X39 Exposure to forces of nature	0.672	0.328	0.000
W65-W74 Accidental drowning and submersion	0.672	0.328	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.672	0.328	0.000
J35.2 Hypertrophy of adenoids	0.671	0.329	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.671	0.329	0.000
C94 Other leukaemias of specified cell type	0.670	0.330	0.000
C01 Malignant neoplasm of base of tongue	0.670	0.330	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.669	0.330	0.000
M25.37 Other instability of joint (Ankle and foot)	0.669	0.331	0.000
H20 Iridocyclitis	0.669	0.331	0.000
M13.1 Monoarthritis, not elsewhere classified	0.668	0.332	0.000
E06.5 Other chronic thyroiditis	0.667	0.333	0.000
E11.8 With unspecified complications	0.667	0.333	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.666	0.334	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.666	0.334	0.000
M35.1 Other overlap syndromes	0.665	0.335	0.000
M25.49 Effusion of joint (Site unspecified)	0.664	0.336	0.000
M25.48 Effusion of joint (Other)	0.664	0.336	0.000
E06.4 Drug-induced thyroiditis	0.664	0.336	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.664	0.336	0.000
E06.0 Acute thyroiditis	0.664	0.336	0.000
M22.4 Chondromalacia patellae	0.663	0.337	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.663	0.337	0.000
E70 Disorders of aromatic amino-acid metabolism	0.663	0.337	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.073	0.337	0.590
M07.36 Other psoriatic arthropathies (Lower leg)	0.662	0.338	0.000
Y28 Contact with sharp object, undetermined intent	0.661	0.339	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.661	0.339	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.661	0.339	0.000
E79 Disorders of purine and pyrimidine metabolism	0.661	0.339	0.000
M25.33 Other instability of joint (Forearm)	0.661	0.339	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.660	0.340	0.000
D06.7 Other parts of cervix	0.659	0.341	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.658	0.342	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.657	0.343	0.000
Y48 Anaesthetics and therapeutic gases	0.657	0.343	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.657	0.343	0.000
M25.83 Other specified joint disorders (Forearm)	0.657	0.343	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.656	0.344	0.000
I00-I02 Acute rheumatic fever	0.655	0.345	0.000
W51 Striking against or bumped into by another person	0.655	0.345	0.000
E03.1 Congenital hypothyroidism without goitre	0.654	0.345	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.654	0.346	0.000
X78 Intentional self-harm by sharp object	0.653	0.347	0.000
H55-H59 Other disorders of eye and adnexa	0.653	0.347	0.000
L12.9 Pemphigoid, unspecified	0.652	0.348	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.651	0.349	0.000
Y07 Other maltreatment syndromes	0.649	0.350	0.000
I22.8 Subsequent myocardial infarction of other sites	0.648	0.352	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.648	0.352	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.648	0.352	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.648	0.352	0.000
C70 Malignant neoplasm of meninges	0.647	0.352	0.000
E10.2 With renal complications	0.647	0.353	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.353	0.647
M06.46 Inflammatory polyarthropathy (Lower leg)	0.647	0.353	0.000
M66.2 Spontaneous rupture of extensor tendons	0.647	0.353	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.646	0.354	0.000
J95.0 Tracheostomy malfunction	0.646	0.354	0.000
E78.3 Hyperchylomicronaemia	0.646	0.354	0.000
E85 Amyloidosis	0.645	0.355	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.644	0.356	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.644	0.356	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.644	0.356	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.644	0.356	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.644	0.356	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.644	0.356	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.644	0.356	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.643	0.357	0.000
D06.0 Endocervix	0.642	0.358	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.641	0.359	0.000
X62.9 Unspecified place	0.641	0.359	0.000
X19 Contact with other and unspecified heat and hot substances	0.640	0.360	0.000
C03.1 Lower gum	0.639	0.361	0.000
I25.3 Aneurysm of heart	0.639	0.361	0.000
M25.39 Other instability of joint (Site unspecified)	0.639	0.361	0.000
M25.38 Other instability of joint (Other)	0.639	0.361	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.639	0.361	0.000
M25.32 Other instability of joint (Upper arm)	0.639	0.361	0.000
M25.30 Other instability of joint (Multiple sites)	0.639	0.361	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.638	0.362	0.000
M60-M63 Disorders of muscles	0.638	0.362	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.637	0.362	0.000
D00.1 Oesophagus	0.637	0.363	0.000
D07.1 Vulva	0.637	0.363	0.000
H40.3 Glaucoma secondary to eye trauma	0.634	0.366	0.000
C06.0 Cheek mucosa	0.634	0.366	0.000
I62 Other nontraumatic intracranial haemorrhage	0.634	0.366	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.633	0.367	0.000
X83 Intentional self-harm by other specified means	0.633	0.367	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations