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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs646776
log Bayes Factor = 128.214
Chromosome 1   position 109,818,530  (GRCh37) Explore rs646776 on Ensembl!
Variant rs646776 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.001 0.999
Z95.0 Presence of cardiac pacemaker
0.000 0.016 0.984
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.024 0.976
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.046 0.954
I21.4 Acute subendocardial myocardial infarction
0.000 0.055 0.945
I71 Aortic aneurysm and dissection
0.000 0.056 0.944
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.057 0.943
I73 Other peripheral vascular diseases
0.000 0.063 0.937
I73.9 Peripheral vascular disease, unspecified
0.000 0.065 0.935
Chapter IX Diseases of the circulatory system
0.000 0.067 0.933
E78.8 Other disorders of lipoprotein metabolism
0.000 0.074 0.926
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.082 0.918
I74 Arterial embolism and thrombosis
0.000 0.093 0.907
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.102 0.898
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.119 0.881
I24 Other acute ischaemic heart diseases
0.000 0.119 0.881
I25.3 Aneurysm of heart
0.000 0.125 0.875
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.152 0.848
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.176 0.824
I24.8 Other forms of acute ischaemic heart disease
0.000 0.202 0.798
E78.4 Other hyperlipidaemia
0.000 0.203 0.797
E78.6 Lipoprotein deficiency
0.000 0.213 0.787
E78.2 Mixed hyperlipidaemia
0.000 0.216 0.784
I50 Heart failure
0.000 0.223 0.777
I30-I52 Other forms of heart disease
0.000 0.226 0.774
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.232 0.768
I25.4 Coronary artery aneurysm
0.000 0.234 0.766
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.234 0.766
I20.8 Other forms of angina pectoris
0.000 0.246 0.754
I22 Subsequent myocardial infarction
0.000 0.247 0.753
I35.0 Aortic (valve) stenosis
0.000 0.247 0.753
I50.0 Congestive heart failure
0.000 0.247 0.753
I35 Nonrheumatic aortic valve disorders
0.000 0.248 0.752
I50.1 Left ventricular failure
0.000 0.251 0.749
I70 Atherosclerosis
0.000 0.261 0.739
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.269 0.731
I23 Certain current complications following acute myocardial infarction
0.000 0.273 0.727
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E78.1 Pure hyperglyceridaemia
0.000 0.285 0.714
I74.8 Embolism and thrombosis of other arteries
0.000 0.297 0.703
I25.5 Ischaemic cardiomyopathy
0.000 0.299 0.701
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.306 0.694
I72 Other aneurysm
0.000 0.308 0.692
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.308 0.692
I50.9 Heart failure, unspecified
0.000 0.309 0.691
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.323 0.676
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.323 0.676
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.323 0.676
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.330 0.670
I00-I02 Acute rheumatic fever
0.000 0.336 0.664
I73.8 Other specified peripheral vascular diseases
0.000 0.341 0.658
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.349 0.650
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.360 0.640
I45 Other conduction disorders
0.000 0.363 0.637
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.364 0.636
I77 Other disorders of arteries and arterioles
0.000 0.367 0.633
Z95.2 Presence of prosthetic heart valve
0.000 0.374 0.626
I45.1 Other and unspecified right bundle-branch block
0.000 0.376 0.624
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.385 0.615
I46 Cardiac arrest
0.000 0.386 0.614
I20.1 Angina pectoris with documented spasm
0.000 0.388 0.612
I72.4 Aneurysm of artery of lower extremity
0.000 0.392 0.608
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.393 0.607
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.399 0.601
I10-I15 Hypertensive diseases
0.000 0.408 0.592
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.409 0.591
I79.1 Aortitis in diseases classified elsewhere
0.000 0.409 0.591
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.409 0.591
I35.8 Other aortic valve disorders
0.000 0.411 0.589
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.414 0.586
I33 Acute and subacute endocarditis
0.000 0.429 0.571
I71.0 Dissection of aorta [any part]
0.000 0.430 0.570
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.431 0.569
I34 Nonrheumatic mitral valve disorders
0.000 0.435 0.565
I40 Acute myocarditis
0.000 0.437 0.562
I24.1 Dressler's syndrome
0.000 0.438 0.562
I72.3 Aneurysm of iliac artery
0.000 0.440 0.560
I52 Other heart disorders in diseases classified elsewhere
0.000 0.445 0.555
I48 Atrial fibrillation and flutter
0.000 0.445 0.555
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.445 0.555
I41 Myocarditis in diseases classified elsewhere
0.000 0.445 0.555
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.445 0.555
I32 Pericarditis in diseases classified elsewhere
0.000 0.445 0.555
I42 Cardiomyopathy
0.000 0.458 0.542
I46.0 Cardiac arrest with successful resuscitation
0.000 0.461 0.539
I70.1 Atherosclerosis of renal artery
0.000 0.462 0.537
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.462 0.537
I70.8 Atherosclerosis of other arteries
0.000 0.467 0.532
I23.8 Other current complications following acute myocardial infarction
0.000 0.469 0.531
I70.9 Generalised and unspecified atherosclerosis
0.000 0.470 0.530
I22.8 Subsequent myocardial infarction of other sites
0.000 0.470 0.530
I34.1 Mitral (valve) prolapse
0.000 0.472 0.528
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.479 0.521
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.521
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.490 0.510
I72.2 Aneurysm of renal artery
0.000 0.490 0.509
I15 Secondary hypertension
0.000 0.491 0.509
I45.2 Bifascicular block
0.000 0.493 0.507
I77.1 Stricture of artery
0.000 0.493 0.507
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.504 0.496
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.504 0.496
I74.5 Embolism and thrombosis of iliac artery
0.000 0.506 0.494
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.507 0.493
I78 Diseases of capillaries
0.000 0.508 0.492
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.510 0.490
I11 Hypertensive heart disease
0.000 0.518 0.482
I70.0 Atherosclerosis of aorta
0.000 0.519 0.481
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.521 0.479
I02 Rheumatic chorea
0.000 0.524 0.476
I01 Rheumatic fever with heart involvement
0.000 0.524 0.476
I00 Rheumatic fever without mention of heart involvement
0.000 0.529 0.471
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.530 0.470
I42.8 Other cardiomyopathies
0.000 0.531 0.469
I21.3 Acute transmural myocardial infarction of unspecified site
0.001 0.536 0.463
I77.2 Rupture of artery
0.000 0.538 0.462
I33.0 Acute and subacute infective endocarditis
0.000 0.540 0.460
I45.0 Right fascicular block
0.000 0.543 0.457
I77.5 Necrosis of artery
0.000 0.546 0.454
I77.4 Coeliac artery compression syndrome
0.000 0.546 0.454
I77.3 Arterial fibromuscular dysplasia
0.000 0.546 0.454
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.546 0.454
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.547 0.453
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.548 0.452
I45.5 Other specified heart block
0.000 0.551 0.449
I72.8 Aneurysm of other specified arteries
0.000 0.555 0.445
I77.6 Arteritis, unspecified
0.000 0.555 0.445
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.556 0.444
I42.2 Other hypertrophic cardiomyopathy
0.000 0.556 0.444
I30 Acute pericarditis
0.000 0.557 0.443
I46.1 Sudden cardiac death, so described
0.000 0.559 0.441
I45.3 Trifascicular block
0.000 0.561 0.439
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.566 0.434
I72.1 Aneurysm of artery of upper extremity
0.000 0.568 0.432
I72.9 Aneurysm of unspecified site
0.000 0.569 0.431
I35.9 Aortic valve disorder, unspecified
0.000 0.570 0.430
I37 Pulmonary valve disorders
0.000 0.570 0.429
I13 Hypertensive heart and renal disease
0.000 0.576 0.424
I38 Endocarditis, valve unspecified
0.000 0.577 0.423
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.579 0.421
I15.9 Seconday hypertension, unspecified
0.000 0.582 0.417
I77.8 Other specified disorders of arteries and arterioles
0.000 0.584 0.416
I15.1 Hypertension secondary to other renal disorders
0.000 0.585 0.415
I40.0 Infective myocarditis
0.000 0.589 0.411
I40.9 Acute myocarditis, unspecified
0.000 0.596 0.403
I40.8 Other acute myocarditis
0.000 0.596 0.403
I40.1 Isolated myocarditis
0.000 0.596 0.403
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.602 0.398
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.602 0.398
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.602 0.398
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.602 0.398
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.602 0.398
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.602 0.398
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.602 0.398
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.602 0.398
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.602 0.398
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.602 0.398
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.602 0.398
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.602 0.398
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.602 0.398
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.602 0.398
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.602 0.398
I48.4 Atypical atrial flutter
0.000 0.602 0.398
I48.3 Typical atrial flutter
0.000 0.602 0.398
I48.2 Chronic atrial fibrillation
0.000 0.602 0.398
I48.1 Persistent atrial fibrillation
0.000 0.602 0.398
I48.0 Paroxysmal atrial fibrillation
0.000 0.602 0.398
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.602 0.398
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.602 0.398
I36 Nonrheumatic tricuspid valve disorders
0.001 0.603 0.396
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.605 0.395
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.606 0.394
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.607 0.393
Z82.2 Family history of deafness and hearing loss
0.000 0.609 0.390
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.610 0.390
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.611 0.388
I42.5 Other restrictive cardiomyopathy
0.000 0.611 0.388
I42.4 Endocardial fibroelastosis
0.000 0.611 0.388
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.611 0.388
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.614 0.385
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.615 0.385
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.618 0.382
I72.0 Aneurysm of carotid artery
0.000 0.618 0.381
I45.9 Conduction disorder, unspecified
0.000 0.619 0.381
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.620 0.380
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.620 0.380
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.621 0.379
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.622 0.378
I42.6 Alcoholic cardiomyopathy
0.000 0.624 0.376
I28 Other diseases of pulmonary vessels
0.000 0.627 0.373
I77.0 Arteriovenous fistula, acquired
0.000 0.633 0.367
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.634 0.366
I15.8 Other secondary hypertension
0.000 0.635 0.365
I15.2 Hypertension secondary to endocrine disorders
0.000 0.635 0.365
I15.0 Renovascular hypertension
0.000 0.635 0.365
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.638 0.362
O34.2 Maternal care due to uterine scar from previous surgery
0.361 0.639 0.000
I33.9 Acute endocarditis, unspecified
0.000 0.640 0.359
I34.0 Mitral (valve) insufficiency
0.000 0.641 0.359
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.645 0.355
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.646 0.353
I78.9 Disease of capillaries, unspecified
0.000 0.647 0.353
I46.9 Cardiac arrest, unspecified
0.000 0.648 0.352
I05-I09 Chronic rheumatic heart diseases
0.000 0.648 0.352
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.649 0.351
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.654 0.345
S00.8 Superficial injury of other parts of head
0.000 0.655 0.345
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.655 0.345
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.659 0.341
I01.8 Other acute rheumatic heart disease
0.000 0.659 0.341
I01.2 Acute rheumatic myocarditis
0.000 0.659 0.341
I01.1 Acute rheumatic endocarditis
0.000 0.659 0.341
I01.0 Acute rheumatic pericarditis
0.000 0.659 0.341
I02.9 Rheumatic chorea without heart involvement
0.000 0.659 0.341
I02.0 Rheumatic chorea with heart involvement
0.000 0.659 0.341
I78.8 Other diseases of capillaries
0.000 0.659 0.341
I45.8 Other specified conduction disorders
0.000 0.663 0.337
Z95.3 Presence of xenogenic heart valve
0.000 0.663 0.336
I45.4 Nonspecific intraventricular block
0.000 0.667 0.333
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.668 0.332
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.680 0.320
I30.8 Other forms of acute pericarditis
0.000 0.682 0.317
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.682 0.317
Z82.1 Family history of blindness and visual loss
0.000 0.684 0.316
I28.8 Other specified diseases of pulmonary vessels
0.000 0.684 0.316
I42.9 Cardiomyopathy, unspecified
0.000 0.688 0.312
I37.9 Pulmonary valve disorder, unspecified
0.000 0.692 0.308
I37.8 Other pulmonary valve disorders
0.000 0.692 0.308
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.692 0.308
I37.0 Pulmonary valve stenosis
0.000 0.692 0.308
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.696 0.304
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.696 0.304
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.696 0.304
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.696 0.304
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.704 0.296
S00 Superficial injury of head
0.000 0.708 0.292
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.715 0.284
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.715 0.284
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.715 0.284
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.715 0.284
I99 Other and unspecified disorders of circulatory system
0.000 0.722 0.278
I30.1 Infective pericarditis
0.000 0.726 0.274
I10 Essential (primary) hypertension
0.000 0.726 0.274
I45.6 Preexcitation syndrome
0.000 0.728 0.272
S00.0 Superficial injury of scalp
0.000 0.732 0.268
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.732 0.268
I28.1 Aneurysm of pulmonary artery
0.000 0.732 0.268
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.732 0.268
I30.9 Acute pericarditis, unspecified
0.000 0.734 0.266
I09 Other rheumatic heart diseases
0.000 0.737 0.263
S00.7 Multiple superficial injuries of head
0.000 0.740 0.260
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.743 0.257
I06 Rheumatic aortic valve diseases
0.000 0.755 0.245
I73.0 Raynaud's syndrome
0.000 0.757 0.243
I07 Rheumatic tricuspid valve diseases
0.000 0.762 0.238
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.788 0.212
S00.1 Contusion of eyelid and periocular area
0.000 0.790 0.210
O34 Maternal care for known or suspected abnormality of pelvic organs
0.208 0.792 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.792 0.208
S00.5 Superficial injury of lip and oral cavity
0.000 0.792 0.208
I05 Rheumatic mitral valve diseases
0.000 0.793 0.207
I31 Other diseases of pericardium
0.000 0.795 0.205
S00.3 Superficial injury of nose
0.000 0.795 0.205
I27 Other pulmonary heart diseases
0.000 0.800 0.200
I09.9 Rheumatic heart disease, unspecified
0.000 0.800 0.199
I12 Hypertensive renal disease
0.000 0.807 0.193
I09.8 Other specified rheumatic heart diseases
0.000 0.811 0.189
I09.2 Chronic rheumatic pericarditis
0.000 0.811 0.189
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.811 0.189
I09.0 Rheumatic myocarditis
0.000 0.811 0.189
I42.0 Dilated cardiomyopathy
0.000 0.814 0.186
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.815 0.185
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.815 0.184
I97.0 Postcardiotomy syndrome
0.000 0.815 0.184
I51 Complications and ill-defined descriptions of heart disease
0.000 0.816 0.184
I78.1 Naevus, nonneoplastic
0.000 0.817 0.183
I37.1 Pulmonary valve insufficiency
0.001 0.817 0.182
S00.4 Superficial injury of ear
0.000 0.821 0.179
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.824 0.176
I06.8 Other rheumatic aortic valve diseases
0.000 0.824 0.176
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.824 0.176
I06.0 Rheumatic aortic stenosis
0.000 0.824 0.176
I26 Pulmonary embolism
0.002 0.827 0.172
S00.9 Superficial injury of head, part unspecified
0.000 0.827 0.173
O34.0 Maternal care for congenital malformation of uterus
0.172 0.828 0.000
I07.9 Tricuspid valve disease, unspecified
0.000 0.829 0.170
I07.8 Other tricuspid valve diseases
0.000 0.829 0.170
I07.2 Tricuspid stenosis with insufficiency
0.000 0.829 0.170
I07.0 Tricuspid stenosis
0.000 0.829 0.170
I05.2 Mitral stenosis with insufficiency
0.000 0.830 0.170
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.831 0.169
I06.1 Rheumatic aortic insufficiency
0.000 0.831 0.169
O34.8 Maternal care for other abnormalities of pelvic organs
0.167 0.833 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.843 0.157
I07.1 Tricuspid insufficiency
0.000 0.844 0.156
O34.1 Maternal care for tumour of corpus uteri
0.152 0.848 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.150 0.850 0.000
O34.6 Maternal care for abnormality of vagina
0.150 0.850 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.150 0.850 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.851 0.149
I05.8 Other mitral valve diseases
0.000 0.851 0.148
I31.8 Other specified diseases of pericardium
0.000 0.853 0.147
I31.2 Haemopericardium, not elsewhere classified
0.000 0.853 0.147
O34.7 Maternal care for abnormality of vulva and perineum
0.147 0.853 0.000
O34.3 Maternal care for cervical incompetence
0.146 0.854 0.000
Z82.3 Family history of stroke
0.000 0.854 0.146
I51.0 Cardiac septal defect, acquired
0.000 0.855 0.145
I05.1 Rheumatic mitral insufficiency
0.000 0.856 0.144
I27.1 Kyphoscoliotic heart disease
0.000 0.856 0.143
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.858 0.142
O34.4 Maternal care for other abnormalities of cervix
0.142 0.858 0.000
I05.0 Mitral stenosis
0.000 0.863 0.137
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.867 0.133
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.868 0.132
I51.9 Heart disease, unspecified
0.000 0.870 0.129
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.873 0.126
I31.0 Chronic adhesive pericarditis
0.000 0.875 0.124
I95 Hypotension
0.000 0.876 0.124
S00-S09 Injuries to the head
0.000 0.876 0.124
I31.1 Chronic constrictive pericarditis
0.000 0.878 0.121
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.879 0.121
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.879 0.121
I98.0 Cardiovascular syphilis
0.000 0.879 0.121
I51.8 Other ill-defined heart diseases
0.000 0.879 0.121
I49 Other cardiac arrhythmias
0.000 0.879 0.121
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.884 0.115
I51.7 Cardiomegaly
0.000 0.884 0.116
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.884 0.115
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.887 0.113
I51.6 Cardiovascular disease, unspecified
0.000 0.891 0.109
I51.5 Myocardial degeneration
0.000 0.892 0.108
S02 Fracture of skull and facial bones
0.000 0.893 0.107
I12.9 Hypertensive renal disease without renal failure
0.000 0.893 0.107
I49.5 Sick sinus syndrome
0.000 0.894 0.106
S02.0 Fracture of vault of skull
0.000 0.897 0.103
I31.3 Pericardial effusion (noninflammatory)
0.000 0.899 0.100
Z95.4 Presence of other heart-valve replacement
0.000 0.900 0.100
S01 Open wound of head
0.000 0.900 0.100
S02.00 Fracture of vault of skull (closed)
0.000 0.900 0.100
S01.9 Open wound of head, part unspecified
0.000 0.902 0.098
S02.2 Fracture of nasal bones
0.000 0.904 0.096
I49.1 Atrial premature depolarisation
0.000 0.905 0.095
I31.9 Disease of pericardium, unspecified
0.000 0.907 0.093
I08 Multiple valve diseases
0.000 0.909 0.091
S01.7 Multiple open wounds of head
0.000 0.909 0.091
I95.9 Hypotension, unspecified
0.000 0.911 0.089
S08 Traumatic amputation of part of head
0.000 0.911 0.089
S07 Crushing injury of head
0.000 0.911 0.089
S04 Injury of cranial nerves
0.000 0.911 0.089
S02.20 Fracture of nasal bones (closed)
0.000 0.911 0.089
S09 Other and unspecified injuries of head
0.000 0.912 0.088
I49.2 Junctional premature depolarisation
0.000 0.913 0.087
S05 Injury of eye and orbit
0.000 0.913 0.087
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.914 0.086
I27.0 Primary pulmonary hypertension
0.000 0.915 0.084
I49.8 Other specified cardiac arrhythmias
0.000 0.917 0.083
I95.1 Orthostatic hypotension
0.000 0.917 0.083
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.918 0.082
I35.1 Aortic (valve) insufficiency
0.001 0.920 0.080
I05.9 Mitral valve disease, unspecified
0.000 0.920 0.080
S01.1 Open wound of eyelid and periocular area
0.000 0.920 0.080
S02.8 Fractures of other skull and facial bones
0.000 0.920 0.080
S02.7 Multiple fractures involving skull and facial bones
0.000 0.921 0.079
S01.3 Open wound of ear
0.000 0.922 0.078
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.923 0.077
I47 Paroxysmal tachycardia
0.000 0.924 0.076
S09.8 Other specified injuries of head
0.000 0.924 0.076
S02.01 Fracture of vault of skull (open)
0.000 0.926 0.074
I95.2 Hypotension due to drugs
0.000 0.929 0.071
K05.3 Chronic periodontitis
0.070 0.930 0.000
S02.6 Fracture of mandible
0.000 0.931 0.069
I27.2 Other secondary pulmonary hypertension
0.000 0.931 0.069
S05.8 Other injuries of eye and orbit
0.000 0.931 0.069
S02.21 Fracture of nasal bones (open)
0.000 0.931 0.069
S01.2 Open wound of nose
0.000 0.932 0.068
S03.2 Dislocation of tooth
0.000 0.933 0.067
I95.0 Idiopathic hypotension
0.000 0.933 0.067
S02.3 Fracture of orbital floor
0.000 0.935 0.065
S05.1 Contusion of eyeball and orbital tissues
0.000 0.935 0.065
I51.4 Myocarditis, unspecified
0.001 0.935 0.065
I95.8 Other hypotension
0.000 0.935 0.064
I49.4 Other and unspecified premature depolarisation
0.000 0.936 0.064
S04.9 Injury of unspecified cranial nerve
0.000 0.936 0.064
S04.8 Injury of other cranial nerves
0.000 0.936 0.064
S04.7 Injury of accessory nerve
0.000 0.936 0.064
S04.6 Injury of acoustic nerve
0.000 0.936 0.064
S04.5 Injury of facial nerve
0.000 0.936 0.064
S04.4 Injury of abducent nerve
0.000 0.936 0.064
S04.3 Injury of trigeminal nerve
0.000 0.936 0.064
S04.2 Injury of trochlear nerve
0.000 0.936 0.064
S04.1 Injury of oculomotor nerve
0.000 0.936 0.064
S04.0 Injury of optic nerve and pathways
0.000 0.936 0.064
S07.9 Crushing injury of head, part unspecified
0.000 0.936 0.064
S07.8 Crushing injury of other parts of head
0.000 0.936 0.064
S07.1 Crushing injury of skull
0.000 0.936 0.064
S07.0 Crushing injury of face
0.000 0.936 0.064
S08.9 Traumatic amputation of unspecified part of head
0.000 0.936 0.064
S08.8 Traumatic amputation of other parts of head
0.000 0.936 0.064
S08.1 Traumatic amputation of ear
0.000 0.936 0.064
S08.0 Avulsion of scalp
0.000 0.936 0.064
S09.7 Multiple injuries of head
0.000 0.936 0.063
S09.2 Traumatic rupture of ear drum
0.000 0.936 0.063
S09.1 Injury of muscle and tendon of head
0.000 0.936 0.063
S05.7 Avulsion of eye
0.000 0.938 0.062
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.938 0.062
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.938 0.062
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.938 0.062
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.938 0.062
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.938 0.062
S05.9 Injury of eye and orbit, part unspecified
0.000 0.938 0.062
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.938 0.061
S03.4 Sprain and strain of jaw
0.000 0.938 0.061
S03.3 Dislocation of other and unspecified parts of head
0.000 0.938 0.061
S03.0 Dislocation of jaw
0.000 0.938 0.061
S01.4 Open wound of cheek and temporomandibular area
0.000 0.939 0.061
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.940 0.060
I08.9 Multiple valve disease, unspecified
0.000 0.940 0.060
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.941 0.059
S02.1 Fracture of base of skull
0.000 0.941 0.059
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.941 0.059
S02.4 Fracture of malar and maxillary bones
0.000 0.941 0.059
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.943 0.057
S02.81 Fractures of other skull and facial bones (open)
0.000 0.943 0.057
S02.5 Fracture of tooth
0.000 0.943 0.057
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.943 0.057
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.945 0.055
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.945 0.055
I08.8 Other multiple valve diseases
0.000 0.948 0.051
S03.1 Dislocation of septal cartilage of nose
0.000 0.949 0.050
S02.61 Fracture of mandible (open)
0.000 0.950 0.050
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.951 0.048
S02.31 Fracture of orbital floor (open)
0.000 0.953 0.047
S09.9 Unspecified injury of head
0.000 0.953 0.047
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.953 0.046
I47.0 Reentry ventricular arrhythmia
0.000 0.957 0.043
K05 Gingivitis and periodontal diseases
0.043 0.957 0.000
S02.60 Fracture of mandible (closed)
0.000 0.957 0.042
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.958 0.042
S01.5 Open wound of lip and oral cavity
0.000 0.958 0.042
S02.51 Fracture of tooth (open)
0.000 0.959 0.041
I49.0 Ventricular fibrillation and flutter
0.000 0.960 0.040
K05.6 Periodontal disease, unspecified
0.037 0.963 0.000
S02.30 Fracture of orbital floor (closed)
0.000 0.964 0.035
S02.11 Fracture of base of skull (open)
0.000 0.965 0.035
S02.10 Fracture of base of skull (closed)
0.000 0.965 0.035
I47.2 Ventricular tachycardia
0.000 0.965 0.035
S06 Intracranial injury
0.000 0.965 0.035
I60-I69 Cerebrovascular diseases
0.000 0.966 0.034
K05.1 Chronic gingivitis
0.034 0.966 0.000
K05.2 Acute periodontitis
0.031 0.969 0.000
K05.4 Periodontosis
0.031 0.969 0.000
K05.0 Acute gingivitis
0.031 0.969 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.970 0.030
S06.3 Focal brain injury
0.000 0.971 0.029
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.971 0.029
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.971 0.029
K05.5 Other periodontal diseases
0.028 0.972 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.973 0.027
I65.2 Occlusion and stenosis of carotid artery
0.000 0.974 0.026
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.974 0.025
S01.8 Open wound of other parts of head
0.000 0.975 0.025
S06.7 Intracranial injury with prolonged coma
0.000 0.975 0.025
S06.1 Traumatic cerebral oedema
0.000 0.975 0.025
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.975 0.025
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.976 0.024
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.976 0.024
I08.0 Disorders of both mitral and aortic valves
0.000 0.976 0.024
S06.4 Epidural haemorrhage
0.000 0.977 0.023
S06.9 Intracranial injury, unspecified
0.000 0.977 0.023
K05.22 Aggressive periodontitis, generalized
0.022 0.978 0.000
S06.2 Diffuse brain injury
0.000 0.978 0.022
S02.50 Fracture of tooth (closed)
0.001 0.978 0.021
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.978 0.021

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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