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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6969131
log Bayes Factor = 7.64503
Chromosome 7   position 5,854,003  (GRCh37) Explore rs6969131 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.996 0.004 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.995 0.005 0.000
I20 Angina pectoris
0.994 0.006 0.000
I25.2 Old myocardial infarction
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.993 0.007 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.986 0.014 0.000
I25.1 Atherosclerotic heart disease
0.983 0.017 0.000
D00-D09 In situ neoplasms
0.979 0.021 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.977 0.023 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.973 0.027 0.000
I60-I69 Cerebrovascular diseases
0.973 0.027 0.000
I20.0 Unstable angina
0.971 0.029 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.969 0.031 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
I20.9 Angina pectoris, unspecified
0.956 0.044 0.000
I69 Sequelae of cerebrovascular disease
0.954 0.046 0.000
S20-S29 Injuries to the thorax
0.946 0.054 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.946 0.054 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.944 0.056 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.942 0.058 0.000
D05 Carcinoma in situ of breast
0.939 0.061 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.938 0.062 0.000
C92 Myeloid leukaemia
0.936 0.064 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.930 0.070 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.927 0.073 0.000
D03 Melanoma in situ
0.910 0.090 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.905 0.095 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.899 0.101 0.000
Y83.4 Other reconstructive surgery
0.895 0.105 0.000
C64-C68 Malignant neoplasms of urinary tract
0.891 0.109 0.000
C82.3 Follicular lymphoma grade IIIa
0.883 0.117 0.000
Chapter XXII Codes for special purposes
0.882 0.118 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.871 0.129 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.870 0.130 0.000
I61 Intracerebral haemorrhage
0.864 0.136 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.862 0.138 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.859 0.141 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.857 0.143 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.854 0.145 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.852 0.148 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.851 0.149 0.000
S27 Injury of other and unspecified intrathoracic organs
0.849 0.151 0.000
Y83.3 Surgical operation with formation of external stoma
0.848 0.152 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.847 0.153 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.842 0.158 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.831 0.169 0.000
I71 Aortic aneurysm and dissection
0.827 0.173 0.000
T66-T78 Other and unspecified effects of external causes
0.826 0.174 0.000
S00-S09 Injuries to the head
0.826 0.174 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.825 0.175 0.000
Y45.0 Opioids and related analgesics
0.823 0.177 0.000
Y84.6 Urinary catheterisation
0.822 0.178 0.000
C67 Malignant neoplasm of bladder
0.819 0.181 0.000
I20.1 Angina pectoris with documented spasm
0.816 0.184 0.000
C92.0 Acute myeloid leukaemia
0.815 0.184 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.814 0.186 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.812 0.188 0.000
I74 Arterial embolism and thrombosis
0.811 0.189 0.000
X20-X29 Contact with venomous animals and plants
0.809 0.191 0.000
S00 Superficial injury of head
0.806 0.194 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.802 0.198 0.000
Y84.8 Other medical procedures
0.800 0.200 0.000
Y95 Nosocomial condition
0.800 0.200 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.799 0.201 0.000
Chapter X Diseases of the respiratory system
0.799 0.201 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.798 0.202 0.000
C91 Lymphoid leukaemia
0.797 0.203 0.000
Y83.0 Surgical operation with transplant of whole organ
0.796 0.204 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.796 0.204 0.000
Y84.0 Cardiac catheterisation
0.793 0.207 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.792 0.208 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.791 0.209 0.000
C45 Mesothelioma
0.789 0.211 0.000
C92.1 Chronic myeloid leukaemia
0.789 0.211 0.000
I70 Atherosclerosis
0.787 0.212 0.000
C93 Monocytic leukaemia
0.787 0.213 0.000
C82.0 Small cleaved cell, follicular
0.785 0.214 0.000
V98-V99 Other and unspecified transport accidents
0.785 0.215 0.000
I23 Certain current complications following acute myocardial infarction
0.782 0.218 0.000
I25.5 Ischaemic cardiomyopathy
0.781 0.219 0.000
I25.3 Aneurysm of heart
0.781 0.219 0.000
V10-V19 Pedal cyclist injured in transport accident
0.780 0.220 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.780 0.220 0.000
J09-J18 Influenza and pneumonia
0.780 0.220 0.000
S00.9 Superficial injury of head, part unspecified
0.779 0.221 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.778 0.222 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.778 0.222 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.777 0.223 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.777 0.223 0.000
C92.7 Other myeloid leukaemia
0.777 0.223 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.776 0.224 0.000
S10-S19 Injuries to the neck
0.773 0.226 0.000
Chapter V Mental and behavioural disorders
0.773 0.227 0.000
T86 Failure and rejection of transplanted organs and tissues
0.770 0.230 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.769 0.231 0.000
V40-V49 Car occupant injured in transport accident
0.768 0.232 0.000
I73 Other peripheral vascular diseases
0.768 0.232 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.765 0.235 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.763 0.237 0.000
Y00-Y09 Assault
0.762 0.238 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.760 0.240 0.000
I62 Other nontraumatic intracranial haemorrhage
0.759 0.241 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
I22 Subsequent myocardial infarction
0.756 0.243 0.000
L50-L54 Urticaria and erythema
0.755 0.245 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.755 0.245 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
D03.4 Melanoma in situ of scalp and neck
0.754 0.246 0.000
J14 Pneumonia due to Haemophilus influenzae
0.753 0.247 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.752 0.248 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.751 0.249 0.000
D06 Carcinoma in situ of cervix uteri
0.749 0.251 0.000
V80-V89 Other land transport accidents
0.746 0.254 0.000
I72 Other aneurysm
0.745 0.255 0.000
T87 Complications peculiar to reattachment and amputation
0.745 0.255 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.744 0.256 0.000
D05.0 Lobular carcinoma in situ
0.742 0.258 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.739 0.261 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.739 0.261 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.739 0.261 0.000
Y52 Agents primarily affecting the cardiovascular system
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.738 0.262 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.737 0.263 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.736 0.264 0.000
S20 Superficial injury of thorax
0.735 0.265 0.000
C15-C26 Malignant neoplasms of digestive organs
0.735 0.265 0.000
J90-J94 Other diseases of pleura
0.734 0.266 0.000
Y83.5 Amputation of limb(s)
0.733 0.267 0.000
I60 Subarachnoid haemorrhage
0.733 0.267 0.000
W00-W19 Falls
0.731 0.269 0.000
C88 Malignant immunoproliferative diseases
0.727 0.273 0.000
Y84.4 Aspiration of fluid
0.727 0.273 0.000
S22.1 Multiple fractures of thoracic spine
0.726 0.274 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.726 0.274 0.000
D03.5 Melanoma in situ of trunk
0.725 0.275 0.000
C67.6 Ureteric orifice
0.725 0.275 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.723 0.277 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.722 0.278 0.000
I24 Other acute ischaemic heart diseases
0.721 0.279 0.000
D41.4 Bladder
0.721 0.279 0.000
M86-M90 Other osteopathies
0.720 0.279 0.000
C84.4 Peripheral T-cell lymphoma
0.720 0.280 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.719 0.281 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.719 0.281 0.000
L20-L30 Dermatitis and eczema
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.717 0.283 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.283 0.000
Y10-Y34 Event of undetermined intent
0.716 0.283 0.000
X85-X99 Assault
0.716 0.283 0.000
X30-X39 Exposure to forces of nature
0.716 0.283 0.000
X10-X19 Contact with heat and hot substances
0.716 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.283 0.000
W75-W84 Other accidental threats to breathing
0.716 0.283 0.000
W65-W74 Accidental drowning and submersion
0.716 0.283 0.000
V95-V97 Air and space transport accidents
0.716 0.283 0.000
V90-V94 Water transport accidents
0.716 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.283 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.716 0.283 0.000
I73.9 Peripheral vascular disease, unspecified
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.715 0.285 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.714 0.286 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.714 0.286 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.713 0.287 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.713 0.287 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.712 0.288 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.712 0.288 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
C95 Leukaemia of unspecified cell type
0.712 0.288 0.000
C94 Other leukaemias of specified cell type
0.712 0.288 0.000
C86 Other specified types of T/NK-cell lymphoma
0.712 0.288 0.000
S00.5 Superficial injury of lip and oral cavity
0.711 0.289 0.000
M65 Synovitis and tenosynovitis
0.711 0.289 0.000
U80 Agent resistant to penicillin and related antibiotics
0.709 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.707 0.293 0.000
S27.2 Traumatic heamopneumothorax
0.704 0.295 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.702 0.298 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.702 0.298 0.000
S50-S59 Injuries to the elbow and forearm
0.700 0.300 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.697 0.303 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.697 0.303 0.000
C45.0 Mesothelioma of pleura
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.696 0.303 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.696 0.304 0.000
C82.6 Cutaneous follicle centre lymphoma
0.694 0.305 0.000
C82.5 Diffuse follicle centre lymphoma
0.694 0.305 0.000
C82.4 Follicular lymphoma grade IIIb
0.694 0.305 0.000
C82.2 Large cell, follicular
0.694 0.305 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.693 0.306 0.000
C67.9 Bladder, unspecified
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.308 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.692 0.308 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.308 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
T36 Poisoning by systemic antibiotics
0.692 0.308 0.000
S22.4 Multiple fractures of ribs
0.691 0.308 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.691 0.309 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.690 0.310 0.000
Y57 Other and unspecified drugs and medicaments
0.690 0.310 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
I21 Acute myocardial infarction
0.688 0.312 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.688 0.312 0.000
D43.2 Brain, unspecified
0.686 0.314 0.000
Y84.1 Kidney dialysis
0.685 0.315 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.684 0.316 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.684 0.316 0.000
S27.3 Other injuries of lung
0.684 0.316 0.000
I61.8 Other intracerebral haemorrhage
0.682 0.318 0.000
T75 Effects of other external causes
0.682 0.318 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.678 0.321 0.000
S26 Injury of heart
0.678 0.321 0.000
S25 Injury of blood vessels of thorax
0.678 0.321 0.000
S24 Injury of nerves and spinal cord at thorax level
0.678 0.321 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.678 0.321 0.000
S21 Open wound of thorax
0.678 0.321 0.000
D37.6 Liver, gallbladder and bile ducts
0.678 0.321 0.000
D37.1 Stomach
0.678 0.322 0.000
Y84.9 Medical procedure, unspecified
0.676 0.323 0.000
Y84.7 Blood-sampling
0.676 0.323 0.000
Y84.5 Insertion of gastric or duodenal sound
0.676 0.323 0.000
Y84.3 Shock therapy
0.676 0.323 0.000
T45.5 Anticoagulants
0.676 0.323 0.000
F60-F69 Disorders of adult personality and behaviour
0.676 0.323 0.000
S27.0 Traumatic pneumothorax
0.675 0.325 0.000
D05.7 Other carcinoma in situ of breast
0.673 0.327 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.673 0.327 0.000
J17 Pneumonia in diseases classified elsewhere
0.673 0.327 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.672 0.328 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.672 0.328 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.672 0.328 0.000
X23 Contact with hornets, wasps and bees
0.672 0.328 0.000
C92.9 Myeloid leukaemia, unspecified
0.671 0.329 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.671 0.329 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.671 0.329 0.000
C92.5 Acute myelomonocytic leukaemia
0.671 0.329 0.000
C92.4 Acute promyelocytic leukaemia
0.671 0.329 0.000
C92.3 Myeloid sarcoma
0.671 0.329 0.000
C92.2 Subacute myeloid leukaemia
0.671 0.329 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.671 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.670 0.329 0.000
Y40 Systemic antibiotics
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.669 0.331 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.667 0.333 0.000
C65 Malignant neoplasm of renal pelvis
0.667 0.333 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.666 0.334 0.000
C84.5 Other and unspecified T-cell lymphomas
0.665 0.334 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.665 0.335 0.000
J91 Pleural effusion in conditions classified elsewhere
0.665 0.335 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.664 0.336 0.000
L29 Pruritus
0.664 0.336 0.000
Q80-Q89 Other congenital malformations
0.664 0.336 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.662 0.338 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.661 0.339 0.000
T45.0 Antiallergic and antiemetic drugs
0.659 0.341 0.000
I77 Other disorders of arteries and arterioles
0.655 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.655 0.345 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.654 0.346 0.000
D03.9 Melanoma in situ, unspecified
0.653 0.347 0.000
D03.8 Melanoma in situ of other sites
0.653 0.347 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.653 0.347 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.653 0.347 0.000
D03.0 Melanoma in situ of lip
0.653 0.347 0.000
U80.1 Methicillin resistant agent
0.653 0.347 0.000
D75 Other diseases of blood and blood-forming organs
0.651 0.349 0.000
C81 Hodgkin's disease
0.651 0.349 0.000
S22.5 Flail chest
0.651 0.349 0.000
M80-M85 Disorders of bone density and structure
0.651 0.349 0.000
I72.4 Aneurysm of artery of lower extremity
0.650 0.350 0.000
C91.1 Chronic lymphocytic leukaemia
0.650 0.350 0.000
T78 Adverse effects, not elsewhere classified
0.648 0.351 0.000
C45.9 Mesothelioma, unspecified
0.648 0.352 0.000
D46 Myelodysplastic syndromes
0.648 0.352 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.648 0.352 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.647 0.353 0.000
T86.1 Kidney transplant failure and rejection
0.647 0.353 0.000
U51 Admission status on psychiatric patients
0.646 0.354 0.000
D37.0 Lip, oral cavity and pharynx
0.646 0.354 0.000
L53 Other erythematous conditions
0.645 0.355 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.644 0.356 0.000
Y98 Lifestyle-related condition
0.644 0.356 0.000
Y97 Environmental-pollution-related condition
0.644 0.356 0.000
Y96 Work-related condition
0.644 0.356 0.000
W19 Unspecified fall
0.644 0.356 0.000
C66 Malignant neoplasm of ureter
0.643 0.357 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.641 0.358 0.000
D70 Agranulocytosis
0.640 0.360 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.640 0.360 0.000
C93.1 Chronic monocytic leukaemia
0.639 0.360 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.639 0.361 0.000
S22.10 Multiple fractures of thoracic spine (closed)
0.639 0.361 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.638 0.361 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.638 0.362 0.000
T91 Sequelae of injuries of neck and trunk
0.637 0.363 0.000
Y83.9 Surgical procedure, unspecified
0.636 0.364 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.634 0.366 0.000
Q00-Q07 Congenital malformations of the nervous system
0.634 0.366 0.000
I21.4 Acute subendocardial myocardial infarction
0.634 0.366 0.000
M40-M43 Deforming dorsopathies
0.632 0.368 0.000
D37.7 Other digestive organs
0.632 0.368 0.000
D02.0 Larynx
0.632 0.368 0.000
V99 Unspecified transport accident
0.631 0.368 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.630 0.369 0.000
M88 Paget's disease of bone [osteitis deformans]
0.630 0.370 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.629 0.370 0.000
S29 Other and unspecified injuries of thorax
0.629 0.371 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.628 0.371 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.627 0.373 0.000
M45-M49 Spondylopathies
0.627 0.373 0.000
J93 Pneumothorax
0.627 0.373 0.000
Y44 Agents primarily affecting blood constituents
0.626 0.374 0.000
I23.8 Other current complications following acute myocardial infarction
0.626 0.374 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.625 0.375 0.000
C46 Kaposi's sarcoma
0.625 0.375 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.624 0.376 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.624 0.376 0.000
T45.8 Other primarily systemic and haematological agents
0.624 0.376 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.624 0.376 0.000
T45.6 Fibrinolysis-affecting drugs
0.624 0.376 0.000
T45.4 Iron and its compounds
0.624 0.376 0.000
T45.3 Enzymes, not elsewhere classified
0.624 0.376 0.000
T45.2 Vitamins, not elsewhere classified
0.624 0.376 0.000
T86.0 Bone-marrow transplant rejection
0.624 0.376 0.000
L51 Erythema multiforme
0.623 0.377 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.622 0.378 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.621 0.379 0.000
S22.0 Fracture of thoracic vertebra
0.621 0.379 0.000
S00.3 Superficial injury of nose
0.621 0.379 0.000
C67.3 Anterior wall of bladder
0.620 0.380 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.620 0.380 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.620 0.380 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.620 0.380 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.620 0.380 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.620 0.380 0.000
S56 Injury of muscle and tendon at forearm level
0.619 0.380 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.619 0.381 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.619 0.381 0.000
S36 Injury of intra-abdominal organs
0.618 0.382 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.618 0.382 0.000
Y45.8 Other analgesics and antipyretics
0.618 0.382 0.000
Y45.5 4-Aminophenol derivatives
0.618 0.382 0.000
Y45.4 Antirheumatics
0.618 0.382 0.000
T14 Injury of unspecified body region
0.617 0.382 0.000
S10 Superficial injury of neck
0.617 0.383 0.000
S70-S79 Injuries to the hip and thigh
0.616 0.384 0.000
T42.4 Benzodiazepines
0.616 0.384 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.616 0.384 0.000
Y54.5 Other diuretics
0.616 0.384 0.000
S27.1 Traumatic haemothorax
0.615 0.384 0.000
D37.2 Small intestine
0.615 0.385 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.614 0.386 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.614 0.386 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.614 0.386 0.000
T42.3 Barbiturates
0.614 0.386 0.000
T42.2 Succinimides and oxazolidinediones
0.614 0.386 0.000
T42.1 Iminostilbenes
0.614 0.386 0.000
T42.0 Hydantoin derivatives
0.614 0.386 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.613 0.386 0.000
M65.3 Trigger finger
0.612 0.388 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.611 0.389 0.000
Q35-Q37 Cleft lip and cleft palate
0.611 0.389 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.611 0.389 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.611 0.389 0.000
Y46.2 Hydantoin derivatives
0.611 0.389 0.000
S06 Intracranial injury
0.611 0.389 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.611 0.389 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.610 0.390 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.610 0.390 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.610 0.390 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.610 0.390 0.000
C84.3 Lymphoepithelioid lymphoma
0.610 0.390 0.000
C84.2 T-zone lymphoma
0.610 0.390 0.000
C84.1 Sezary's diease
0.610 0.390 0.000
C84.0 Mycosis fungoides
0.610 0.390 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.610 0.390 0.000
C15 Malignant neoplasm of oesophagus
0.610 0.390 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.609 0.391 0.000
S27.9 Injury of unspecified intrathoracic organ
0.609 0.391 0.000
S27.8 Injury of other specified intrathoracic organs
0.609 0.391 0.000
S27.7 Multiple injuries of intrathoracic organs
0.609 0.391 0.000
S27.6 Injury of pleura
0.609 0.391 0.000
S27.5 Injury of thoracic trachea
0.609 0.391 0.000
S27.4 Injury of bronchus
0.609 0.391 0.000
Y65 Other misadventures during surgical and medical care
0.608 0.392 0.000
S22.9 Fracture of bony thorax, part unspecified
0.607 0.392 0.000
S22.8 Fracture of other parts of bony thorax
0.607 0.392 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.607 0.393 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.607 0.393 0.000
T13 Other injuries of lower limb, level unspecified
0.606 0.394 0.000
D38.1 Trachea, bronchus and lung
0.606 0.394 0.000
T39.1 4-Aminophenol derivatives
0.606 0.394 0.000
M90 Osteopathies in diseases classified elsewhere
0.605 0.395 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.605 0.395 0.000
S12 Fracture of neck
0.605 0.395 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.605 0.395 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.605 0.395 0.000
Y84.2 Radiological procedure and radiotherapy
0.604 0.396 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.601 0.399 0.000
I69.3 Sequelae of cerebral infarction
0.600 0.400 0.000
L52 Erythema nodosum
0.600 0.400 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.599 0.401 0.000
T39.0 Salicylates
0.599 0.401 0.000
C16 Malignant neoplasm of stomach
0.599 0.401 0.000
S22.3 Fracture of rib
0.599 0.401 0.000
Q60-Q64 Congenital malformations of the urinary system
0.599 0.401 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.598 0.402 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.598 0.402 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.597 0.403 0.000
I22.8 Subsequent myocardial infarction of other sites
0.596 0.403 0.000
D09 Carcinoma in situ of other and unspecified sites
0.596 0.404 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.596 0.404 0.000
D37.9 Digestive organ, unspecified
0.595 0.404 0.000
D37.3 Appendix
0.595 0.404 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.595 0.405 0.000
Y60.0 During surgical operation
0.595 0.405 0.000
T63 Toxic effect of contact with venomous animals
0.594 0.406 0.000
D37.4 Colon
0.593 0.406 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.593 0.407 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.593 0.407 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.593 0.407 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.593 0.407 0.000
T74 Maltreatment syndromes
0.593 0.407 0.000
T73 Effects of other deprivation
0.593 0.407 0.000
T70 Effects of air pressure and water pressure
0.593 0.407 0.000
T69 Other effects of reduced temperature
0.593 0.407 0.000
T67 Effects of heat and light
0.593 0.407 0.000
T71 Asphyxiation
0.593 0.407 0.000
T66 Unspecified effects of radiation
0.593 0.407 0.000
S08 Traumatic amputation of part of head
0.592 0.408 0.000
S07 Crushing injury of head
0.592 0.408 0.000
S04 Injury of cranial nerves
0.592 0.408 0.000
Y64 Contaminated medical or biological substances
0.592 0.408 0.000
Y63 Failure in dosage during surgical and medical care
0.592 0.408 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.592 0.408 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.592 0.408 0.000
Y69 Unspecified misadventure during surgical and medical care
0.592 0.408 0.000
Y66 Nonadministration of surgical and medical care
0.592 0.408 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.592 0.408 0.000
Y00 Assault by blunt object
0.591 0.409 0.000
F30-F39 Mood [affective] disorders
0.591 0.409 0.000
T87.4 Infection of amputation stump
0.590 0.410 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.590 0.410 0.000
D75.2 Essential thrombocytosis
0.589 0.411 0.000
T87.6 Other and unspecified complications of amputation stump
0.589 0.411 0.000
S05 Injury of eye and orbit
0.588 0.411 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.588 0.412 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.588 0.412 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.588 0.412 0.000
D69 Purpura and other haemorrhagic conditions
0.588 0.412 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.587 0.413 0.000
C67.8 Overlapping lesion of bladder
0.587 0.413 0.000
C67.7 Urachus
0.587 0.413 0.000
C67.1 Dome of bladder
0.587 0.413 0.000
C67.0 Trigone of bladder
0.587 0.413 0.000
C91.4 Hairy-cell leukaemia
0.585 0.415 0.000
D41.0 Kidney
0.585 0.415 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.585 0.415 0.000
D06.9 Cervix, unspecified
0.584 0.416 0.000
S32 Fracture of lumbar spine and pelvis
0.584 0.416 0.000
L10-L14 Bullous disorders
0.584 0.416 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.584 0.416 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.583 0.417 0.000
D66 Hereditary factor VIII deficiency
0.583 0.417 0.000
F80-F89 Disorders of psychological development
0.583 0.417 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.582 0.418 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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