TreeWAS – Variant ID: rs7045620

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
J09-J18 Influenza and pneumonia	1.000	0.000
J18 Pneumonia, organism unspecified	0.999	0.001
Chapter V Mental and behavioural disorders	0.998	0.002
J18.1 Lobar pneumonia, unspecified	0.997	0.003
J20-J22 Other acute lower respiratory infections	0.995	0.005
M20-M25 Other joint disorders	0.994	0.006
M70-M79 Other soft tissue disorders	0.992	0.008
J22 Unspecified acute lower respiratory infection	0.992	0.008
M79 Other soft tissue disorders, not elsewhere classified	0.988	0.012
S80-S89 Injuries to the knee and lower leg	0.976	0.024
M79.6 Pain in limb	0.963	0.037
J18.9 Pneumonia, unspecified	0.962	0.038
M80-M85 Disorders of bone density and structure	0.962	0.038
Chapter VII Diseases of the eye and adnexa	0.960	0.040
Chapter XX External causes of morbidity and mortality	0.958	0.042
M25 Other joint disorders, not elsewhere classified	0.956	0.044
M20 Acquired deformities of fingers and toes	0.948	0.052
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.946	0.054
S70-S79 Injuries to the hip and thigh	0.942	0.058
Chapter I Certain infectious and parasitic diseases	0.941	0.059
F30-F39 Mood [affective] disorders	0.938	0.062
F00-F09 Organic, including symptomatic, mental disorders	0.938	0.062
S81 Open wound of lower leg	0.933	0.067
M81 Osteoporosis without pathological fracture	0.925	0.075
M20.1 Hallux valgus (acquired)	0.920	0.080
M79.67 Pain in limb (Ankle and foot)	0.910	0.090
M25.5 Pain in joint	0.907	0.093
S82 Fracture of lower leg, including ankle	0.901	0.099
Chapter VI Diseases of the nervous system	0.901	0.099
S72 Fracture of femur	0.900	0.100
M81.9 Osteoporosis, unspecified	0.898	0.102
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.898	0.102
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.897	0.103
W00-W19 Falls	0.897	0.103
M79.66 Pain in limb (Lower leg)	0.894	0.106
Chapter XI Diseases of the digestive system	0.886	0.114
B95-B98 Bacterial, viral and other infectious agents	0.885	0.115
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.884	0.116
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.881	0.119
M81.99 Osteoporosis, unspecified (Site unspecified)	0.877	0.123
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.873	0.127
S81.9 Open wound of lower leg, part unspecified	0.869	0.131
K70-K77 Diseases of liver	0.864	0.136
F40-F48 Neurotic, stress-related and somatoform disorders	0.862	0.138
F10 Mental and behavioural disorders due to use of alcohol	0.861	0.139
J40-J47 Chronic lower respiratory diseases	0.860	0.140
H25-H28 Disorders of lens	0.858	0.142
S82.8 Fractures of other parts of lower leg	0.856	0.144
K50-K52 Noninfective enteritis and colitis	0.855	0.145
M79.0 Rheumatism, unspecified	0.852	0.148
F03 Unspecified dementia	0.843	0.157
J95-J99 Other diseases of the respiratory system	0.843	0.157
M50-M54 Other dorsopathies	0.840	0.159
Chapter IX Diseases of the circulatory system	0.839	0.161
M25.56 Pain in joint (Lower leg)	0.834	0.166
M79.7 Fibromyalgia	0.832	0.168
M79.1 Myalgia	0.830	0.170
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.830	0.170
F33 Recurrent depressive disorder	0.829	0.171
A00-A09 Intestinal infectious diseases	0.829	0.171
Chapter IV Endocrine, nutritional and metabolic diseases	0.829	0.171
J44 Other chronic obstructive pulmonary disease	0.829	0.171
H00 Hordeolum and chalazion	0.827	0.173
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.827	0.173
K50 Crohn's disease [regional enteritis]	0.825	0.175
S82.80 Fractures of other parts of lower leg (closed)	0.823	0.177
I95-I99 Other and unspecified disorders of the circulatory system	0.822	0.178
J00-J06 Acute upper respiratory infections	0.821	0.179
M20.2 Hallux rigidus	0.816	0.184
T88 Other complications of surgical and medical care, not elsewhere classified	0.816	0.184
F32 Depressive episode	0.816	0.184
S00-S09 Injuries to the head	0.816	0.184
H43-H45 Disorders of vitreous body and globe	0.814	0.186
W20-W49 Exposure to inanimate mechanical forces	0.813	0.187
Chapter XXII Codes for special purposes	0.810	0.190
J14 Pneumonia due to Haemophilus influenzae	0.808	0.192
I95 Hypotension	0.808	0.192
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.805	0.195
W19 Unspecified fall	0.802	0.198
M30 Polyarteritis nodosa and related conditions	0.801	0.199
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.800	0.200
G20-G26 Extrapyramidal and movement disorders	0.798	0.202
M25.51 Pain in joint (Shoulder region)	0.798	0.202
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.797	0.203
S72.1 Pertrochanteric fracture	0.796	0.204
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.795	0.205
S72.0 Fracture of neck of femur	0.793	0.207
S20-S29 Injuries to the thorax	0.792	0.208
F10.2 Dependence syndrome	0.792	0.208
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.792	0.208
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.788	0.212
M25.6 Stiffness of joint, not elsewhere classified	0.787	0.213
S81.8 Open wound of other parts of lower leg	0.786	0.214
R29.6 Tendency to fall, not elsewhere classified	0.786	0.214
K76 Other diseases of liver	0.785	0.215
T81 Complications of procedures, not elsewhere classified	0.784	0.216
M22 Disorders of patella	0.783	0.217
M79.60 Pain in limb (Multiple sites)	0.782	0.218
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.781	0.219
M21 Other acquired deformities of limbs	0.780	0.220
K50.9 Crohn's disease, unspecified	0.774	0.226
M79.8 Other specified soft tissue disorders	0.773	0.227
J90-J94 Other diseases of pleura	0.772	0.227
H00.1 Chalazion	0.772	0.228
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.772	0.228
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.770	0.230
T93 Sequelae of injuries of lower limb	0.770	0.230
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.770	0.230
M86-M90 Other osteopathies	0.769	0.231
S60-S69 Injuries to the wrist and hand	0.766	0.234
M45-M49 Spondylopathies	0.766	0.234
M05-M14 Inflammatory polyarthropathies	0.766	0.234
Chapter XIV Diseases of the genitourinary system	0.765	0.235
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.765	0.235
S40-S49 Injuries to the shoulder and upper arm	0.764	0.236
M34 Systemic sclerosis	0.764	0.236
H25 Senile cataract	0.762	0.238
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.761	0.239
S90-S99 Injuries to the ankle and foot	0.759	0.240
I95.1 Orthostatic hypotension	0.758	0.242
M79.63 Pain in limb (Forearm)	0.755	0.245
D60-D64 Aplastic and other anaemias	0.755	0.245
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.754	0.246
T15-T19 Effects of foreign body entering through natural orifice	0.751	0.249
I95.9 Hypotension, unspecified	0.749	0.251
M25.0 Haemarthrosis	0.749	0.251
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.748	0.252
W07 Fall involving chair	0.746	0.254
M31 Other necrotising vasculopathies	0.744	0.255
M25.4 Effusion of joint	0.744	0.256
H55-H59 Other disorders of eye and adnexa	0.743	0.257
M79.09 Rheumatism, unspecified (Site unspecified)	0.742	0.258
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.742	0.258
M24 Other specific joint derangements	0.741	0.259
G00-G09 Inflammatory diseases of the central nervous system	0.740	0.260
K70 Alcoholic liver disease	0.740	0.260
H02 Other disorders of eyelid	0.739	0.261
V40-V49 Car occupant injured in transport accident	0.739	0.261
G90-G99 Other disorders of the nervous system	0.738	0.262
J80-J84 Other respiratory diseases principally affecting the interstitium	0.738	0.262
J18.0 Bronchopneumonia, unspecified	0.735	0.265
G30-G32 Other degenerative diseases of the nervous system	0.734	0.266
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.734	0.266
M85 Other disorders of bone density and structure	0.732	0.268
F33.9 Recurrent depressive disorder, unspecified	0.731	0.269
F43 Reaction to severe stress, and adjustment disorders	0.730	0.270
K74 Fibrosis and cirrhosis of liver	0.729	0.271
E50-E64 Other nutritional deficiencies	0.727	0.273
J98 Other respiratory disorders	0.726	0.274
S72.3 Fracture of shaft of femur	0.726	0.274
Y60-Y69 Misadventures to patients during surgical and medical care	0.725	0.274
N25-N29 Other disorders of kidney and ureter	0.725	0.275
T79-T79 Certain early complications of trauma	0.724	0.276
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.724	0.276
M84 Disorders of continuity of bone	0.723	0.277
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.722	0.278
S72.10 Pertrochanteric fracture (closed)	0.721	0.279
M79.79 Fibromyalgia (Site unspecified)	0.720	0.280
M72 Fibroblastic disorders	0.719	0.281
J60-J70 Lung diseases due to external agents	0.718	0.281
M79.18 Myalgia (Other)	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
S72.00 Fracture of neck of femur (closed)	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
J17 Pneumonia in diseases classified elsewhere	0.717	0.283
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.717	0.283
J15 Bacterial pneumonia, not elsewhere classified	0.717	0.283
J12 Viral pneumonia, not elsewhere classified	0.717	0.283
J11 Influenza, virus not identified	0.717	0.283
J10 Influenza due to identified influenza virus	0.717	0.283
J13 Pneumonia due to Streptococcus pneumoniae	0.717	0.283
J09 Influenza due to certain identified influenza virus	0.717	0.283
J18.8 Other pneumonia, organism unspecified	0.716	0.283
J18.2 Hypostatic pneumonia, unspecified	0.716	0.283
F99-F99 Unspecified mental disorder	0.716	0.284
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F80-F89 Disorders of psychological development	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
F60-F69 Disorders of adult personality and behaviour	0.716	0.284
T66-T78 Other and unspecified effects of external causes	0.715	0.285
F05 Delirium, not induced by alcohol and other psychoactive substances	0.715	0.285
F00 Dementia in Alzheimer's disease	0.714	0.286
J21 Acute bronchiolitis	0.714	0.286
J20 Acute bronchitis	0.714	0.286
T86 Failure and rejection of transplanted organs and tissues	0.713	0.287
H10-H13 Disorders of conjunctiva	0.713	0.287
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.713	0.287
M33 Dermatopolymyositis	0.713	0.287
M32 Systemic lupus erythematosus	0.713	0.287
M35 Other systemic involvement of connective tissue	0.712	0.288
A09.9 Gastroenteritis and colitis of unspecified origin	0.712	0.288
M76 Enthesopathies of lower limb, excluding foot	0.711	0.289
M73 Soft tissue disorders in diseases classified elsewhere	0.711	0.289
M71 Other bursopathies	0.711	0.289
M77 Other enthesopathies	0.711	0.289
K76.9 Liver disease, unspecified	0.710	0.290
S89 Other and unspecified injuries of lower leg	0.709	0.290
S81.0 Open wound of knee	0.709	0.291
H25.9 Senile cataract, unspecified	0.709	0.291
H01 Other inflammation of eyelid	0.709	0.291
M79.9 Soft tissue disorder, unspecified	0.708	0.291
M79.5 Residual foreign body in soft tissue	0.708	0.291
M79.4 Hypertrophy of (infrapatellar) fat pad	0.708	0.291
M79.3 Panniculitis, unspecified	0.708	0.291
M79.2 Neuralgia and neuritis, unspecified	0.708	0.291
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.708	0.292
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
F31 Bipolar affective disorder	0.708	0.292
D80-D89 Certain disorders involving the immune mechanism	0.707	0.292
S82.4 Fracture of fibula alone	0.706	0.294
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.706	0.294
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.706	0.294
F52 Sexual dysfunction, not caused by organic disorder or disease	0.704	0.296
J40 Bronchitis, not specified as acute or chronic	0.704	0.296
M40-M43 Deforming dorsopathies	0.701	0.298
A80-A89 Viral infections of the central nervous system	0.701	0.299
G80-G83 Cerebral palsy and other paralytic syndromes	0.701	0.299
Q60-Q64 Congenital malformations of the urinary system	0.701	0.299
F10.3 Withdrawal state	0.700	0.300
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.700	0.300
S88 Traumatic amputation of lower leg	0.699	0.300
S87 Crushing injury of lower leg	0.699	0.300
S86 Injury of muscle and tendon at lower leg level	0.699	0.300
S85 Injury of blood vessels at lower leg level	0.699	0.300
S84 Injury of nerves at lower leg level	0.699	0.300
M65-M68 Disorders of synovium and tendon	0.699	0.301
F32.1 Moderate depressive episode	0.699	0.301
W10 Fall on and from stairs and steps	0.699	0.301
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.697	0.303
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.697	0.303
Q38-Q45 Other congenital malformations of the digestive system	0.696	0.304
N28 Other disorders of kidney and ureter, not elsewhere classified	0.696	0.304
K02 Dental caries	0.692	0.308
D50-D53 Nutritional anaemias	0.692	0.308
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.690	0.310
M79.68 Pain in limb (Other)	0.690	0.310
M79.64 Pain in limb (Hand)	0.690	0.310
M79.61 Pain in limb (Shoulder region)	0.690	0.310
M81.90 Osteoporosis, unspecified (Multiple sites)	0.690	0.310
M83 Adult osteomalacia	0.689	0.310
M82 Osteoporosis in diseases classified elsewhere	0.689	0.310
M80 Osteoporosis with pathological fracture	0.689	0.310
F10.0 Acute intoxication	0.689	0.311
T81.8 Other complications of procedures, not elsewhere classified	0.689	0.311
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.688	0.311
D63 Anaemia in chronic diseases classified elsewhere	0.688	0.312
H46-H48 Disorders of optic nerve and visual pathways	0.688	0.312
M20.4 Other hammer toe(s) (acquired)	0.688	0.312
T92 Sequelae of injuries of upper limb	0.688	0.312
V10-V19 Pedal cyclist injured in transport accident	0.687	0.312
F01 Vascular dementia	0.687	0.313
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.687	0.313
Y35-Y36 Legal intervention and operations of war	0.687	0.313
Y10-Y34 Event of undetermined intent	0.687	0.313
Y00-Y09 Assault	0.687	0.313
X85-X99 Assault	0.687	0.313
X58-X59 Accidental exposure to other and unspecified factors	0.687	0.313
X50-X57 Overexertion, travel and privation	0.687	0.313
X40-X49 Accidental poisoning by and exposure to noxious substances	0.687	0.313
X30-X39 Exposure to forces of nature	0.687	0.313
X20-X29 Contact with venomous animals and plants	0.687	0.313
X10-X19 Contact with heat and hot substances	0.687	0.313
X00-X09 Exposure to smoke, fire and flames	0.687	0.313
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.687	0.313
W75-W84 Other accidental threats to breathing	0.687	0.313
W65-W74 Accidental drowning and submersion	0.687	0.313
W50-W64 Exposure to animate mechanical forces	0.687	0.313
V98-V99 Other and unspecified transport accidents	0.687	0.313
V95-V97 Air and space transport accidents	0.687	0.313
V90-V94 Water transport accidents	0.687	0.313
V80-V89 Other land transport accidents	0.687	0.313
V70-V79 Bus occupant injured in transport accident	0.687	0.313
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.687	0.313
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.687	0.313
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.687	0.313
V01-V09 Pedestrian injured in transport accident	0.687	0.313
M25.9 Joint disorder, unspecified	0.686	0.314
M25.8 Other specified joint disorders	0.686	0.314
M25.3 Other instability of joint	0.686	0.314
M25.2 Flail joint	0.686	0.314
M25.1 Fistula of joint	0.686	0.314
M70 Soft tissue disorders related to use, overuse and pressure	0.685	0.315
Y52 Agents primarily affecting the cardiovascular system	0.683	0.317
H02.8 Other specified disorders of eyelid	0.682	0.318
K51 Ulcerative colitis	0.681	0.319
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.681	0.319
X60-X84 Intentional self-harm	0.681	0.319
V20-V29 Motorcycle rider injured in transport accident	0.680	0.320
M20.3 Other deformity of hallux (acquired)	0.679	0.321
M20.0 Deformity of finger(s)	0.679	0.321
F40 Phobic anxiety disorders	0.679	0.321
H52 Disorders of refraction and accommodation	0.679	0.321
G70-G73 Diseases of myoneural junction and muscle	0.679	0.321
T87 Complications peculiar to reattachment and amputation	0.678	0.322
T80 Complications following infusion, transfusion and therapeutic injection	0.678	0.322
M25.55 Pain in joint (Pelvic region and thigh)	0.677	0.323
Q50-Q56 Congenital malformations of genital organs	0.677	0.323
T81.3 Disruption of operation wound, not elsewhere classified	0.677	0.323
M50 Cervical disk disorders	0.677	0.323
S06 Intracranial injury	0.677	0.323
B15-B19 Viral hepatitis	0.676	0.323
S70 Superficial injury of hip and thigh	0.676	0.324
S79 Other and unspecified injuries of hip and thigh	0.675	0.325
S78 Traumatic amputation of hip and thigh	0.675	0.325
S77 Crushing injury of hip and thigh	0.675	0.325
S76 Injury of muscle and tendon at hip and thigh level	0.675	0.325
S75 Injury of blood vessels at hip and thigh level	0.675	0.325
S74 Injury of nerves at hip and thigh level	0.675	0.325
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.675	0.325
S71 Open wound of hip and thigh	0.675	0.325
B99-B99 Other infectious diseases	0.674	0.326
B90-B94 Sequelae of infectious and parasitic diseases	0.674	0.326
B85-B89 Pediculosis, acariasis and other infestations	0.674	0.326
B65-B83 Helminthiases	0.674	0.326
B50-B64 Protozoal diseases	0.674	0.326
B20-B24 Human immunodeficiency virus [HIV] disease	0.674	0.326
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.674	0.326
A75-A79 Rickettsioses	0.674	0.326
A70-A74 Other diseases caused by chlamydiae	0.674	0.326
A65-A69 Other spirochaetal diseases	0.674	0.326
A50-A64 Infections with a predominantly sexual mode of transmission	0.674	0.326
A20-A28 Certain zoonotic bacterial diseases	0.674	0.326
A15-A19 Tuberculosis	0.674	0.326
H26 Other cataract	0.673	0.327
M25.50 Pain in joint (Multiple sites)	0.673	0.327
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.673	0.327
F38 Other mood [affective] disorders	0.672	0.328
F34 Persistent mood [affective] disorders	0.672	0.328
F30 Manic episode	0.672	0.328
F39 Unspecified mood [affective] disorder	0.672	0.328
W19.9 Unspecified place	0.672	0.328
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.672	0.328
F02 Dementia in other diseases classified elsewhere	0.672	0.328
F09 Unspecified organic or symptomatic mental disorder	0.672	0.328
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.672	0.328
H44 Disorders of globe	0.672	0.328
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.672	0.328
K50.8 Other Crohn's disease	0.672	0.328
N10-N16 Renal tubulo-interstitial diseases	0.671	0.329
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.670	0.330
K72 Hepatic failure, not elsewhere classified	0.670	0.330
S81.7 Multiple open wounds of lower leg	0.669	0.331
J42 Unspecified chronic bronchitis	0.669	0.331
N00-N08 Glomerular diseases	0.668	0.332
S62 Fracture at wrist and hand level	0.668	0.332
M54 Dorsalgia	0.668	0.332
K35-K38 Diseases of appendix	0.668	0.332
J04 Acute laryngitis and tracheitis	0.667	0.333
G25 Other extrapyramidal and movement disorders	0.666	0.334
K76.6 Portal hypertension	0.666	0.334
T88.4 Failed or difficult intubation	0.666	0.334
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.665	0.335
F10.1 Harmful use	0.665	0.335
S82.1 Fracture of upper end of tibia	0.664	0.336
M81.8 Other osteoporosis	0.663	0.337
M81.6 Localised osteoporosis [Lequesne]	0.663	0.337
M81.5 Idiopathic osteoporosis	0.663	0.337
M81.4 Drug-induced osteoporosis	0.663	0.337
M81.3 Postsurgical malabsorption osteoporosis	0.663	0.337
M81.2 Osteoporosis of disuse	0.663	0.337
M81.1 Postoophorectomy osteoporosis	0.663	0.337
M81.0 Postmenopausal osteoporosis	0.663	0.337
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.663	0.337
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.663	0.337
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.662	0.338
T93.9 Sequelae of unspecified injury of lower limb	0.659	0.341
R25 Abnormal involuntary movements	0.659	0.341
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.658	0.342
K50.1 Crohn's disease of large intestine	0.656	0.344
M22.4 Chondromalacia patellae	0.654	0.346
N28.1 Cyst of kidney, acquired	0.654	0.346
S82.0 Fracture of patella	0.654	0.346
G24 Dystonia	0.653	0.347
S80 Superficial injury of lower leg	0.651	0.348
B97 Viral agents as the cause of diseases classified to other chapters	0.651	0.349
J99 Respiratory disorders in diseases classified elsewhere	0.651	0.349
M25.59 Pain in joint (Site unspecified)	0.650	0.350
M25.58 Pain in joint (Other)	0.650	0.350
M25.54 Pain in joint (Hand)	0.650	0.350
M25.53 Pain in joint (Forearm)	0.650	0.350
M25.52 Pain in joint (Upper arm)	0.650	0.350
M75 Shoulder lesions	0.648	0.352
A02 Other Salmonella infections	0.648	0.352
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.648	0.352
S82.9 Fracture of lower leg, part unspecified	0.646	0.354
S82.7 Multiple fractures of lower leg	0.646	0.354
S82.5 Fracture of medial malleolus	0.646	0.354
S72.9 Fracture of femur, part unspecified	0.645	0.355
S72.8 Fractures of other parts of femur	0.645	0.355
S72.7 Multiple fractures of femur	0.645	0.355
S72.4 Fracture of lower end of femur	0.645	0.355
S72.2 Subtrochanteric fracture	0.645	0.355
W19.2 School, other institution and public administrative area	0.645	0.355
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.644	0.356
M81.96 Osteoporosis, unspecified (Lower leg)	0.644	0.356
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.644	0.356
M81.94 Osteoporosis, unspecified (Hand)	0.644	0.356
M81.93 Osteoporosis, unspecified (Forearm)	0.644	0.356
M81.92 Osteoporosis, unspecified (Upper arm)	0.644	0.356
M81.91 Osteoporosis, unspecified (Shoulder region)	0.644	0.356
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.644	0.356
H05 Disorders of orbit	0.644	0.356
H03 Disorders of eyelid in diseases classified elsewhere	0.644	0.356
H43 Disorders of vitreous body	0.644	0.356
J02 Acute pharyngitis	0.644	0.356
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.643	0.357
F18 Mental and behavioural disorders due to use of volatile solvents	0.643	0.357
F16 Mental and behavioural disorders due to use of hallucinogens	0.643	0.357
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.643	0.357
F14 Mental and behavioural disorders due to use of cocaine	0.643	0.357
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.643	0.357
F12 Mental and behavioural disorders due to use of cannabinoids	0.643	0.357
F11 Mental and behavioural disorders due to use of opioids	0.643	0.357
Q20-Q28 Congenital malformations of the circulatory system	0.643	0.357
F33.1 Recurrent depressive disorder, current episode moderate	0.643	0.357
W18 Other fall on same level	0.643	0.357
W17 Other fall from one level to another	0.643	0.357
W16 Diving or jumping into water causing injury other than drowning or submersion	0.643	0.357
W15 Fall from cliff	0.643	0.357
W14 Fall from tree	0.643	0.357
W13 Fall from, out of or through building or structure	0.643	0.357
W12 Fall on and from scaffolding	0.643	0.357
W11 Fall on and from ladder	0.643	0.357
W09 Fall involving playground equipment	0.643	0.357
W08 Fall involving other furniture	0.643	0.357
W06 Fall involving bed	0.643	0.357
W05 Fall involving wheelchair	0.643	0.357
W04 Fall while being carried or supported by other persons	0.643	0.357
W03 Other fall on same level due to collision with, or pushing by, another person	0.643	0.357
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.643	0.357
W01 Fall on same level from slipping, tripping and stumbling	0.643	0.357
W00 Fall on same level involving ice and snow	0.643	0.357
N17-N19 Renal failure	0.642	0.358
E40-E46 Malnutrition	0.641	0.359
E53 Deficiency of other B group vitamins	0.641	0.359
T84.0 Mechanical complication of internal joint prosthesis	0.641	0.359
K75 Other inflammatory liver diseases	0.640	0.360
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.639	0.361
M79.69 Pain in limb (Site unspecified)	0.639	0.361
S02 Fracture of skull and facial bones	0.639	0.361
J03 Acute tonsillitis	0.639	0.361
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.638	0.361
S22 Fracture of rib(s), sternum and thoracic spine	0.638	0.362
M20.6 Acquired deformity of toe(s), unspecified	0.638	0.362
S82.2 Fracture of shaft of tibia	0.638	0.362
W07.0 Home	0.637	0.363
M79.00 Rheumatism, unspecified (Multiple sites)	0.637	0.363
W21 Striking against or struck by sports equipment	0.637	0.363
I85 Oesophageal varices	0.636	0.364
Chapter VIII Diseases of the ear and mastoid process	0.636	0.364
K02.9 Dental caries, unspecified	0.635	0.365
D55-D59 Haemolytic anaemias	0.634	0.366
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.634	0.366
W29 Contact with other powered hand tools and household machinery	0.632	0.367
F32.3 Severe depressive episode with psychotic symptoms	0.632	0.368
T98 Sequelae of other and unspecified effects of external causes	0.631	0.369
T95 Sequelae of burns, corrosions and frostbite	0.631	0.369
T94 Sequelae of injuries involving multiple and unspecified body regions	0.631	0.369
T91 Sequelae of injuries of neck and trunk	0.631	0.369
T90 Sequelae of injuries of head	0.631	0.369
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.631	0.369
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.631	0.369
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.629	0.371
M81.98 Osteoporosis, unspecified (Other)	0.629	0.371
J44.9 Chronic obstructive pulmonary disease, unspecified	0.629	0.371
W19.4 Street and highway	0.629	0.371
D63.8 Anaemia in other chronic diseases classified elsewhere	0.627	0.372
R93 Abnormal findings on diagnostic imaging of other body structures	0.627	0.373
M21.0 Valgus deformity, not elsewhere classified	0.627	0.373
F32.0 Mild depressive episode	0.626	0.374
Y95 Nosocomial condition	0.626	0.374
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.626	0.374
Q80-Q89 Other congenital malformations	0.626	0.374
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.626	0.374
Q35-Q37 Cleft lip and cleft palate	0.626	0.374
Q30-Q34 Congenital malformations of the respiratory system	0.626	0.374
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.626	0.374
Q00-Q07 Congenital malformations of the nervous system	0.626	0.374
J44.8 Other specified chronic obstructive pulmonary disease	0.625	0.374
F45 Somatoform disorders	0.625	0.375
R27 Other lack of coordination	0.625	0.375
G04 Encephalitis, myelitis and encephalomyelitis	0.624	0.376
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.624	0.376
F06.7 Mild cognitive disorder	0.623	0.377
S69 Other and unspecified injuries of wrist and hand	0.622	0.377
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.621	0.379
S50-S59 Injuries to the elbow and forearm	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations