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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7146393
log Bayes Factor = 7.92483
Chromosome 14   position 32,787,754  (GRCh37) Explore rs7146393 on Ensembl!
Variant rs7146393 is part of Cluster X0013

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
G90-G99 Other disorders of the nervous system
0.987 0.013 0.000
F30-F39 Mood [affective] disorders
0.972 0.028 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.971 0.029 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.969 0.031 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.967 0.033 0.000
Chapter VIII Diseases of the ear and mastoid process
0.965 0.035 0.000
W20-W49 Exposure to inanimate mechanical forces
0.949 0.051 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.946 0.054 0.000
E10-E14 Diabetes mellitus
0.945 0.055 0.000
H65-H75 Diseases of middle ear and mastoid
0.943 0.057 0.000
G96 Other disorders of central nervous system
0.940 0.060 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.938 0.062 0.000
E20-E35 Disorders of other endocrine glands
0.937 0.063 0.000
M45-M49 Spondylopathies
0.936 0.064 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.934 0.066 0.000
M20-M25 Other joint disorders
0.925 0.075 0.000
S80-S89 Injuries to the knee and lower leg
0.920 0.080 0.000
S90-S99 Injuries to the ankle and foot
0.919 0.081 0.000
E10 Insulin-dependent diabetes mellitus
0.917 0.083 0.000
M80-M85 Disorders of bone density and structure
0.917 0.083 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.915 0.085 0.000
S00-S09 Injuries to the head
0.914 0.086 0.000
G93 Other disorders of brain
0.910 0.090 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.908 0.092 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.907 0.093 0.000
S00 Superficial injury of head
0.902 0.098 0.000
F30 Manic episode
0.899 0.101 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.895 0.105 0.000
F03 Unspecified dementia
0.895 0.105 0.000
T43.2 Other and unspecified antidepressants
0.894 0.106 0.000
S00.8 Superficial injury of other parts of head
0.892 0.108 0.000
H74 Other disorders of middle ear and mastoid
0.892 0.108 0.000
H66 Suppurative and unspecified otitis media
0.890 0.110 0.000
G95 Other diseases of spinal cord
0.889 0.111 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.887 0.113 0.000
M25 Other joint disorders, not elsewhere classified
0.887 0.113 0.000
M47 Spondylosis
0.885 0.115 0.000
F31 Bipolar affective disorder
0.880 0.120 0.000
T92 Sequelae of injuries of upper limb
0.870 0.130 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.863 0.137 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.862 0.138 0.000
E23 Hypofunction and other disorders of pituitary gland
0.861 0.139 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.861 0.139 0.000
S50-S59 Injuries to the elbow and forearm
0.860 0.140 0.000
G30-G32 Other degenerative diseases of the nervous system
0.859 0.141 0.000
H60-H62 Diseases of external ear
0.857 0.143 0.000
M86-M90 Other osteopathies
0.855 0.145 0.000
S20-S29 Injuries to the thorax
0.855 0.145 0.000
Y86 Sequelae of other accidents
0.855 0.145 0.000
M47.8 Other spondylosis
0.853 0.147 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.853 0.147 0.000
F99-F99 Unspecified mental disorder
0.853 0.147 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.851 0.149 0.000
G96.0 Cerebrospinal fluid leak
0.850 0.150 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.849 0.151 0.000
F33 Recurrent depressive disorder
0.847 0.153 0.000
M50-M54 Other dorsopathies
0.846 0.154 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.846 0.154 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.844 0.156 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.843 0.157 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.841 0.159 0.000
H66.9 Otitis media, unspecified
0.839 0.161 0.000
M25.8 Other specified joint disorders
0.838 0.162 0.000
W25 Contact with sharp glass
0.835 0.165 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.834 0.166 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.834 0.166 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.833 0.167 0.000
S82 Fracture of lower leg, including ankle
0.832 0.168 0.000
M25.4 Effusion of joint
0.832 0.168 0.000
S00.9 Superficial injury of head, part unspecified
0.827 0.173 0.000
E10.9 Without complications
0.824 0.176 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.822 0.178 0.000
G96.8 Other specified disorders of central nervous system
0.822 0.178 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.821 0.179 0.000
Y52 Agents primarily affecting the cardiovascular system
0.818 0.182 0.000
M40-M43 Deforming dorsopathies
0.818 0.182 0.000
W44 Foreign body entering into or through eye or natural orifice
0.817 0.183 0.000
Y85 Sequelae of transport accidents
0.817 0.183 0.000
F30.9 Manic episode, unspecified
0.816 0.184 0.000
E10.5 With peripheral circulatory complications
0.812 0.188 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.809 0.191 0.000
M84 Disorders of continuity of bone
0.808 0.192 0.000
E40-E46 Malnutrition
0.806 0.194 0.000
E22 Hyperfunction of pituitary gland
0.804 0.196 0.000
V01-V09 Pedestrian injured in transport accident
0.803 0.197 0.000
G93.6 Cerebral oedema
0.802 0.198 0.000
F60-F69 Disorders of adult personality and behaviour
0.801 0.199 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.801 0.199 0.000
M70-M79 Other soft tissue disorders
0.799 0.201 0.000
M00-M03 Infectious arthropathies
0.798 0.201 0.000
F20 Schizophrenia
0.797 0.203 0.000
E26 Hyperaldosteronism
0.796 0.204 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.796 0.204 0.000
M47.86 Other spondylosis (Lumbar region)
0.796 0.204 0.000
M21 Other acquired deformities of limbs
0.795 0.205 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.794 0.206 0.000
S31 Open wound of abdomen, lower back and pelvis
0.793 0.207 0.000
G95.1 Vascular myelopathies
0.792 0.208 0.000
H74.4 Polyp of middle ear
0.791 0.209 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.788 0.212 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.787 0.213 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.782 0.218 0.000
M22 Disorders of patella
0.781 0.219 0.000
S00.7 Multiple superficial injuries of head
0.780 0.220 0.000
X60-X84 Intentional self-harm
0.780 0.220 0.000
M80 Osteoporosis with pathological fracture
0.779 0.221 0.000
T00-T07 Injuries involving multiple body regions
0.777 0.223 0.000
S51 Open wound of forearm
0.777 0.223 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.777 0.223 0.000
F02 Dementia in other diseases classified elsewhere
0.775 0.225 0.000
G90 Disorders of autonomic nervous system
0.775 0.225 0.000
F25 Schizoaffective disorders
0.773 0.227 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.772 0.228 0.000
M89 Other disorders of bone
0.771 0.229 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.770 0.230 0.000
E13 Other specified diabetes mellitus
0.770 0.230 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.769 0.231 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.769 0.231 0.000
G91 Hydrocephalus
0.769 0.231 0.000
S90 Superficial injury of ankle and foot
0.768 0.232 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.768 0.232 0.000
S82.6 Fracture of lateral malleolus
0.767 0.233 0.000
E11 Non-insulin-dependent diabetes mellitus
0.766 0.234 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.765 0.235 0.000
M25.84 Other specified joint disorders (Hand)
0.765 0.235 0.000
H74.0 Tympanosclerosis
0.762 0.238 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.762 0.238 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.761 0.239 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.757 0.243 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
Y44 Agents primarily affecting blood constituents
0.754 0.246 0.000
M25.46 Effusion of joint (Lower leg)
0.754 0.246 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.753 0.246 0.000
W25.9 Unspecified place
0.753 0.247 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.753 0.247 0.000
S92 Fracture of foot, except ankle
0.752 0.248 0.000
G93.3 Postviral fatigue syndrome
0.752 0.248 0.000
G93.2 Benign intracranial hypertension
0.752 0.248 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.751 0.249 0.000
G70-G73 Diseases of myoneural junction and muscle
0.750 0.250 0.000
Y57 Other and unspecified drugs and medicaments
0.749 0.251 0.000
T36 Poisoning by systemic antibiotics
0.748 0.252 0.000
F99 Mental disorder, not otherwise specified
0.748 0.252 0.000
T51 Toxic effect of alcohol
0.747 0.253 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.747 0.253 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.744 0.256 0.000
M45 Ankylosing spondylitis
0.744 0.256 0.000
S99 Other and unspecified injuries of ankle and foot
0.743 0.257 0.000
S91 Open wound of ankle and foot
0.743 0.257 0.000
E10.4 With neurological complications
0.742 0.258 0.000
M50 Cervical disk disorders
0.742 0.258 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.742 0.258 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.742 0.258 0.000
Y65 Other misadventures during surgical and medical care
0.741 0.259 0.000
E10.1 With ketoacidosis
0.739 0.261 0.000
S05 Injury of eye and orbit
0.739 0.261 0.000
F40 Phobic anxiety disorders
0.739 0.261 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.737 0.263 0.000
E10.0 With coma
0.736 0.264 0.000
Y49.5 Other antipsychotics and neuroleptics
0.736 0.264 0.000
M82 Osteoporosis in diseases classified elsewhere
0.735 0.265 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.735 0.265 0.000
E11.5 With peripheral circulatory complications
0.734 0.266 0.000
E23.0 Hypopituitarism
0.734 0.266 0.000
M60-M63 Disorders of muscles
0.734 0.266 0.000
S81 Open wound of lower leg
0.733 0.267 0.000
W21 Striking against or struck by sports equipment
0.732 0.268 0.000
M47.82 Other spondylosis (Cervical region)
0.731 0.269 0.000
F30.2 Mania with psychotic symptoms
0.731 0.269 0.000
H61 Other disorders of external ear
0.730 0.270 0.000
H69 Other disorders of Eustachian tube
0.726 0.274 0.000
G95.2 Cord compression, unspecified
0.725 0.275 0.000
M34 Systemic sclerosis
0.724 0.276 0.000
E24 Cushing's syndrome
0.724 0.276 0.000
W44.0 Home
0.723 0.277 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.722 0.278 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.721 0.279 0.000
S82.60 Fracture of lateral malleolus (closed)
0.721 0.279 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M72 Fibroblastic disorders
0.717 0.283 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.717 0.283 0.000
E23.2 Diabetes insipidus
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
F01 Vascular dementia
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
G93.8 Other specified disorders of brain
0.714 0.286 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.714 0.286 0.000
E29 Testicular dysfunction
0.714 0.286 0.000
Y95 Nosocomial condition
0.714 0.286 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.713 0.287 0.000
M47.9 Spondylosis, unspecified
0.712 0.288 0.000
F33.8 Other recurrent depressive disorders
0.712 0.288 0.000
G14 Postpolio syndrome
0.712 0.288 0.000
S82.2 Fracture of shaft of tibia
0.710 0.290 0.000
H60 Otitis externa
0.710 0.290 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.709 0.291 0.000
Y49.2 Other and unspecified antidepressants
0.709 0.291 0.000
T42.4 Benzodiazepines
0.709 0.291 0.000
T39.1 4-Aminophenol derivatives
0.709 0.291 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.708 0.292 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.708 0.292 0.000
G92 Toxic encephalopathy
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.706 0.294 0.000
H66.3 Other chronic suppurative otitis media
0.704 0.296 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.698 0.302 0.000
F39 Unspecified mood [affective] disorder
0.698 0.302 0.000
T46.1 Calcium-channel blockers
0.697 0.303 0.000
F40.2 Specific (isolated) phobias
0.697 0.303 0.000
F20.9 Schizophrenia, unspecified
0.697 0.303 0.000
F38 Other mood [affective] disorders
0.697 0.303 0.000
F34 Persistent mood [affective] disorders
0.697 0.303 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.696 0.304 0.000
E26.0 Primary hyperaldosteronism
0.696 0.304 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.696 0.304 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.695 0.305 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.695 0.305 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.695 0.305 0.000
F09 Unspecified organic or symptomatic mental disorder
0.695 0.305 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.695 0.305 0.000
T90 Sequelae of injuries of head
0.694 0.306 0.000
T43.9 Psychotropic drug, unspecified
0.693 0.307 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.693 0.307 0.000
T43.6 Psychostimulants with abuse potential
0.693 0.307 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.693 0.307 0.000
Chapter XXII Codes for special purposes
0.692 0.308 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.691 0.309 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.691 0.309 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.690 0.310 0.000
E27 Other disorders of adrenal gland
0.690 0.310 0.000
F05.9 Delirium, unspecified
0.689 0.311 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.689 0.311 0.000
M51 Other intervertebral disk disorders
0.689 0.311 0.000
M86 Osteomyelitis
0.688 0.312 0.000
S32 Fracture of lumbar spine and pelvis
0.688 0.312 0.000
E46 Unspecified protein-energy malnutrition
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.688 0.312 0.000
M21.3 Wrist or foot drop (acquired)
0.687 0.313 0.000
W00-W19 Falls
0.687 0.313 0.000
E23.7 Disorder of pituitary gland, unspecified
0.686 0.314 0.000
X50-X57 Overexertion, travel and privation
0.685 0.314 0.000
G31.8 Other specified degenerative diseases of nervous system
0.685 0.315 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.685 0.315 0.000
M49 Spondylopathies in diseases classified elsewhere
0.684 0.316 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.684 0.316 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
S31.1 Open wound of abdominal wall
0.683 0.317 0.000
W20 Struck by thrown, projected or falling object
0.683 0.317 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.681 0.319 0.000
W46 Contact with hypodermic needle
0.681 0.319 0.000
W45 Foreign body or object entering through skin
0.681 0.319 0.000
W43 Exposure to vibration
0.681 0.319 0.000
W42 Exposure to noise
0.681 0.319 0.000
W41 Exposure to high-pressure jet
0.681 0.319 0.000
W40 Explosion of other materials
0.681 0.319 0.000
W39 Discharge of firework
0.681 0.319 0.000
W38 Explosion and rupture of other specified pressurised devices
0.681 0.319 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.681 0.319 0.000
W36 Explosion and rupture of gas cylinder
0.681 0.319 0.000
W35 Explosion and rupture of boiler
0.681 0.319 0.000
W34 Discharge from other and unspecified firearms
0.681 0.319 0.000
W33 Rifle, shotgun and larger firearm discharge
0.681 0.319 0.000
W32 Handgun discharge
0.681 0.319 0.000
W31 Contact with other and unspecified machinery
0.681 0.319 0.000
W30 Contact with agricultural machinery
0.681 0.319 0.000
W28 Contact with powered lawn mower
0.681 0.319 0.000
W27 Contact with nonpowered hand tool
0.681 0.319 0.000
W26 Contact with knife, sword or dagger
0.681 0.319 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.681 0.319 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.681 0.319 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.681 0.319 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.680 0.320 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.680 0.320 0.000
F80-F89 Disorders of psychological development
0.679 0.321 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.679 0.321 0.000
E22.0 Acromegaly and pituitary gigantism
0.679 0.321 0.000
Y59 Other and unspecified vaccines and biological substances
0.678 0.322 0.000
Y58 Bacterial vaccines
0.678 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.678 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.322 0.000
S29 Other and unspecified injuries of thorax
0.678 0.322 0.000
E12 Malnutrition-related diabetes mellitus
0.678 0.322 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.677 0.323 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.676 0.324 0.000
H68 Eustachian salpingitis and obstruction
0.676 0.324 0.000
H67 Otitis media in diseases classified elsewhere
0.676 0.324 0.000
G00 Bacterial meningitis, not elsewhere classified
0.676 0.324 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.675 0.325 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.675 0.325 0.000
G96.9 Disorder of central nervous system, unspecified
0.674 0.326 0.000
G95.8 Other specified diseases of spinal cord
0.672 0.327 0.000
G20-G26 Extrapyramidal and movement disorders
0.672 0.328 0.000
Q50-Q56 Congenital malformations of genital organs
0.672 0.328 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.672 0.328 0.000
E32 Diseases of thymus
0.672 0.328 0.000
E31 Polyglandular dysfunction
0.672 0.328 0.000
E30 Disorders of puberty, not elsewhere classified
0.672 0.328 0.000
E25 Adrenogenital disorders
0.672 0.328 0.000
T42.1 Iminostilbenes
0.670 0.330 0.000
S86 Injury of muscle and tendon at lower leg level
0.670 0.330 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.669 0.330 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.669 0.330 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.669 0.330 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.669 0.330 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.669 0.330 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.669 0.330 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.669 0.330 0.000
T44.0 Anticholinesterase agents
0.669 0.330 0.000
W29 Contact with other powered hand tools and household machinery
0.669 0.330 0.000
Y89 Sequelae of other external causes
0.669 0.331 0.000
M25.47 Effusion of joint (Ankle and foot)
0.669 0.331 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.668 0.332 0.000
F00 Dementia in Alzheimer's disease
0.668 0.332 0.000
F22 Persistent delusional disorders
0.667 0.333 0.000
T79-T79 Certain early complications of trauma
0.667 0.333 0.000
M91-M94 Chondropathies
0.666 0.333 0.000
H71 Cholesteatoma of middle ear
0.666 0.334 0.000
M41 Scoliosis
0.665 0.335 0.000
M22.2 Patellofemoral disorders
0.665 0.335 0.000
V04 Pedestrian injured in collision with heavy transport vehicle or bus
0.663 0.337 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.663 0.337 0.000
M32 Systemic lupus erythematosus
0.663 0.337 0.000
M30 Polyarteritis nodosa and related conditions
0.663 0.337 0.000
S00.5 Superficial injury of lip and oral cavity
0.663 0.337 0.000
M23 Internal derangement of knee
0.663 0.337 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.663 0.337 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
F05.1 Delirium superimposed on dementia
0.662 0.338 0.000
T92.1 Sequelae of fracture of arm
0.662 0.338 0.000
E20 Hypoparathyroidism
0.662 0.338 0.000
M25.44 Effusion of joint (Hand)
0.662 0.338 0.000
E28 Ovarian dysfunction
0.661 0.339 0.000
T51.0 Ethanol
0.661 0.339 0.000
H70 Mastoiditis and related conditions
0.661 0.339 0.000
F33.9 Recurrent depressive disorder, unspecified
0.661 0.339 0.000
M25.3 Other instability of joint
0.660 0.340 0.000
S88 Traumatic amputation of lower leg
0.660 0.340 0.000
S87 Crushing injury of lower leg
0.660 0.340 0.000
S85 Injury of blood vessels at lower leg level
0.660 0.340 0.000
S84 Injury of nerves at lower leg level
0.660 0.340 0.000
V40-V49 Car occupant injured in transport accident
0.660 0.340 0.000
F60 Specific personality disorders
0.659 0.340 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.659 0.341 0.000
S98 Traumatic amputation of ankle and foot
0.659 0.341 0.000
S97 Crushing injury of ankle and foot
0.659 0.341 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.659 0.341 0.000
S95 Injury of blood vessels at ankle and foot level
0.659 0.341 0.000
S94 Injury of nerves at ankle and foot level
0.659 0.341 0.000
S36 Injury of intra-abdominal organs
0.658 0.342 0.000
S56 Injury of muscle and tendon at forearm level
0.658 0.342 0.000
M46 Other inflammatory spondylopathies
0.658 0.342 0.000
E10.8 With unspecified complications
0.658 0.342 0.000
E10.7 With multiple complications
0.658 0.342 0.000
E10.6 With other specified complications
0.658 0.342 0.000
M83 Adult osteomalacia
0.658 0.342 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.657 0.343 0.000
F30.0 Hypomania
0.657 0.343 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.656 0.344 0.000
T95 Sequelae of burns, corrosions and frostbite
0.656 0.344 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.656 0.344 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.656 0.344 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.656 0.344 0.000
S08 Traumatic amputation of part of head
0.655 0.344 0.000
S07 Crushing injury of head
0.655 0.344 0.000
S04 Injury of cranial nerves
0.655 0.344 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.655 0.344 0.000
E11.6 With other specified complications
0.655 0.344 0.000
T98 Sequelae of other and unspecified effects of external causes
0.655 0.345 0.000
M89.8 Other specified disorders of bone
0.655 0.345 0.000
E34 Other endocrine disorders
0.655 0.345 0.000
M00 Pyogenic arthritis
0.655 0.345 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.654 0.346 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.654 0.346 0.000
M24 Other specific joint derangements
0.653 0.346 0.000
M84.0 Malunion of fracture
0.653 0.347 0.000
S27 Injury of other and unspecified intrathoracic organs
0.653 0.347 0.000
F25.9 Schizoaffective disorder, unspecified
0.653 0.347 0.000
D68 Other coagulation defects
0.653 0.347 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.653 0.347 0.000
G93.7 Reye's syndrome
0.652 0.348 0.000
G93.5 Compression of brain
0.652 0.348 0.000
Y45.1 Salicylates
0.652 0.348 0.000
M25.86 Other specified joint disorders (Lower leg)
0.652 0.348 0.000
Y65.4 Failure to introduce or to remove other tube or instrument
0.652 0.348 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.651 0.349 0.000
S37 Injury of urinary and pelvic organs
0.651 0.349 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.651 0.349 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.651 0.349 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.651 0.349 0.000
F28 Other nonorganic psychotic disorders
0.650 0.350 0.000
F24 Induced delusional disorder
0.650 0.350 0.000
F21 Schizotypal disorder
0.650 0.350 0.000
D69 Purpura and other haemorrhagic conditions
0.650 0.350 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.650 0.350 0.000
S50 Superficial injury of forearm
0.650 0.350 0.000
M50.1 Cervical disk disorder with radiculopathy
0.650 0.350 0.000
S51.8 Open wound of other parts of forearm
0.649 0.351 0.000
S00.4 Superficial injury of ear
0.647 0.353 0.000
V80-V89 Other land transport accidents
0.646 0.354 0.000
F29 Unspecified nonorganic psychosis
0.646 0.354 0.000
S22.2 Fracture of sternum
0.645 0.355 0.000
M50.3 Other cervical disk degeneration
0.645 0.355 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.645 0.355 0.000
F30.8 Other manic episodes
0.644 0.355 0.000
F30.1 Mania without psychotic symptoms
0.644 0.355 0.000
E50-E64 Other nutritional deficiencies
0.644 0.356 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.644 0.356 0.000
E13.9 Without complications
0.644 0.356 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.644 0.356 0.000
Y45.8 Other analgesics and antipyretics
0.643 0.357 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.642 0.358 0.000
M99 Biomechanical lesions, not elsewhere classified
0.642 0.358 0.000
S82.0 Fracture of patella
0.640 0.360 0.000
M47.89 Other spondylosis (Site unspecified)
0.640 0.360 0.000
T39.0 Salicylates
0.639 0.361 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.639 0.361 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.639 0.361 0.000
H74.1 Adhesive middle ear disease
0.639 0.361 0.000
M25.7 Osteophyte
0.639 0.361 0.000
G90.2 Horner's syndrome
0.639 0.361 0.000
S81.0 Open wound of knee
0.639 0.361 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.639 0.361 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.638 0.362 0.000
Y57.5 X-ray contrast media
0.638 0.362 0.000
H66.4 Suppurative otitis media, unspecified
0.638 0.362 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.638 0.362 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.638 0.362 0.000
H66.0 Acute suppurative otitis media
0.638 0.362 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.638 0.362 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.637 0.363 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.637 0.363 0.000
F02.3 Dementia in Parkinson's disease
0.637 0.363 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.637 0.363 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.636 0.364 0.000
T39.4 Antirheumatics, not elsewhere classified
0.636 0.364 0.000
T39.2 Pyrazolone derivatives
0.636 0.364 0.000
M25.9 Joint disorder, unspecified
0.636 0.364 0.000
M25.2 Flail joint
0.636 0.364 0.000
M25.1 Fistula of joint
0.636 0.364 0.000
H73 Other disorders of tympanic membrane
0.636 0.364 0.000
E65-E68 Obesity and other hyperalimentation
0.636 0.364 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.635 0.365 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.635 0.365 0.000
G95.0 Syringomyelia and syringobulbia
0.634 0.366 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.634 0.366 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.633 0.367 0.000
T13 Other injuries of lower limb, level unspecified
0.632 0.368 0.000
S51.0 Open wound of elbow
0.632 0.368 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.632 0.368 0.000
F43 Reaction to severe stress, and adjustment disorders
0.632 0.368 0.000
T14 Injury of unspecified body region
0.631 0.369 0.000
M65-M68 Disorders of synovium and tendon
0.631 0.369 0.000
M89.9 Disorder of bone, unspecified
0.631 0.369 0.000
F31.8 Other bipolar affective disorders
0.631 0.369 0.000
F31.7 Bipolar affective disorder, currently in remission
0.631 0.369 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.631 0.369 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.631 0.369 0.000
G12 Spinal muscular atrophy and related syndromes
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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