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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs71471187
log Bayes Factor = 15.1039
Chromosome 10   position 87,819,622  (GRCh37) Explore rs71471187 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
M54 Dorsalgia
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
M54.5 Low back pain
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.987 0.013 0.000
R50-R69 General symptoms and signs
0.986 0.014 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.984 0.016 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.984 0.016 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.984 0.016 0.000
K21 Gastro-oesophageal reflux disease
0.983 0.017 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.982 0.018 0.000
R55 Syncope and collapse
0.981 0.019 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.980 0.020 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.979 0.021 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.978 0.022 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.972 0.028 0.000
M54.57 Low back pain (Lumbosacral region)
0.971 0.029 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.968 0.032 0.000
Z92 Personal history of medical treatment
0.965 0.035 0.000
Y43 Primarily systemic agents
0.964 0.036 0.000
F30-F39 Mood [affective] disorders
0.964 0.036 0.000
K50-K52 Noninfective enteritis and colitis
0.960 0.040 0.000
R40 Somnolence, stupor and coma
0.955 0.045 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.953 0.047 0.000
B95-B98 Bacterial, viral and other infectious agents
0.953 0.047 0.000
M45-M49 Spondylopathies
0.950 0.050 0.000
A30-A49 Other bacterial diseases
0.949 0.051 0.000
Chapter VIII Diseases of the ear and mastoid process
0.949 0.051 0.000
Y43.3 Other antineoplastic drugs
0.941 0.059 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.935 0.065 0.000
Chapter II Neoplasms
0.934 0.066 0.000
E70-E90 Metabolic disorders
0.933 0.067 0.000
F32 Depressive episode
0.928 0.072 0.000
R40.0 Somnolence
0.923 0.077 0.000
Z93 Artificial opening status
0.916 0.084 0.000
M79.0 Rheumatism, unspecified
0.913 0.087 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.902 0.098 0.000
E50-E64 Other nutritional deficiencies
0.900 0.100 0.000
H65-H75 Diseases of middle ear and mastoid
0.896 0.104 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.895 0.105 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.894 0.105 0.000
B35-B49 Mycoses
0.894 0.106 0.000
K51 Ulcerative colitis
0.893 0.107 0.000
M79.6 Pain in limb
0.890 0.110 0.000
E86 Volume depletion
0.889 0.111 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.885 0.115 0.000
K90-K93 Other diseases of the digestive system
0.882 0.118 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.880 0.120 0.000
M54.50 Low back pain (Multiple sites in spine)
0.879 0.121 0.000
M54.56 Low back pain (Lumbar region)
0.877 0.123 0.000
K50 Crohn's disease [regional enteritis]
0.875 0.125 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.874 0.126 0.000
R52 Pain, not elsewhere classified
0.874 0.126 0.000
R53 Malaise and fatigue
0.874 0.126 0.000
R60 Oedema, not elsewhere classified
0.874 0.126 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.873 0.127 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.872 0.128 0.000
M54.3 Sciatica
0.870 0.130 0.000
Chapter VI Diseases of the nervous system
0.870 0.130 0.000
M47 Spondylosis
0.870 0.130 0.000
A41 Other septicaemia
0.869 0.131 0.000
D50-D53 Nutritional anaemias
0.868 0.132 0.000
Z88.6 Personal history of allergy to analgesic agent
0.867 0.133 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.865 0.135 0.000
M48 Other spondylopathies
0.863 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.862 0.138 0.000
Z88.2 Personal history of allergy to sulphonamides
0.861 0.139 0.000
E20-E35 Disorders of other endocrine glands
0.861 0.139 0.000
R47-R49 Symptoms and signs involving speech and voice
0.852 0.148 0.000
K29 Gastritis and duodenitis
0.852 0.148 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.847 0.153 0.000
F32.9 Depressive episode, unspecified
0.846 0.154 0.000
A49 Bacterial infection of unspecified site
0.845 0.155 0.000
C60-C63 Malignant neoplasms of male genital organs
0.844 0.156 0.000
Z90.7 Acquired absence of genital organ(s)
0.844 0.156 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.843 0.157 0.000
M54.2 Cervicalgia
0.841 0.159 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.840 0.160 0.000
M54.4 Lumbago with sciatica
0.839 0.161 0.000
K31 Other diseases of stomach and duodenum
0.839 0.161 0.000
W20-W49 Exposure to inanimate mechanical forces
0.837 0.163 0.000
H60-H62 Diseases of external ear
0.832 0.168 0.000
E83 Disorders of mineral metabolism
0.828 0.171 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.828 0.172 0.000
F60-F69 Disorders of adult personality and behaviour
0.827 0.173 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.826 0.173 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.826 0.174 0.000
Z60 Problems related to social environment
0.825 0.175 0.000
K51.9 Ulcerative colitis, unspecified
0.824 0.176 0.000
C64-C68 Malignant neoplasms of urinary tract
0.823 0.177 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.823 0.177 0.000
Chapter XIV Diseases of the genitourinary system
0.822 0.178 0.000
M79.67 Pain in limb (Ankle and foot)
0.822 0.178 0.000
M72 Fibroblastic disorders
0.820 0.180 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.818 0.182 0.000
K92 Other diseases of digestive system
0.817 0.183 0.000
M54.59 Low back pain (Site unspecified)
0.816 0.184 0.000
M79.7 Fibromyalgia
0.814 0.186 0.000
R94 Abnormal results of function studies
0.814 0.186 0.000
K70-K77 Diseases of liver
0.809 0.191 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.805 0.194 0.000
W00-W19 Falls
0.805 0.195 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.805 0.195 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.804 0.196 0.000
K50.9 Crohn's disease, unspecified
0.802 0.198 0.000
M48.0 Spinal stenosis
0.800 0.200 0.000
D50 Iron deficiency anaemia
0.798 0.202 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.797 0.203 0.000
M80-M85 Disorders of bone density and structure
0.796 0.204 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.793 0.207 0.000
Z93.0 Tracheostomy status
0.793 0.207 0.000
D60-D64 Aplastic and other anaemias
0.791 0.209 0.000
M71 Other bursopathies
0.791 0.209 0.000
M54.9 Dorsalgia, unspecified
0.790 0.210 0.000
K27 Peptic ulcer, site unspecified
0.788 0.212 0.000
M47.9 Spondylosis, unspecified
0.787 0.213 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.786 0.214 0.000
D68 Other coagulation defects
0.786 0.214 0.000
R00 Abnormalities of heart beat
0.785 0.215 0.000
R40.2 Coma, unspecified
0.785 0.215 0.000
Z90.0 Acquired absence of part of head and neck
0.784 0.216 0.000
Z90.3 Acquired absence of part of stomach
0.783 0.217 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.782 0.218 0.000
B25-B34 Other viral diseases
0.782 0.218 0.000
E55 Vitamin D deficiency
0.782 0.218 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.781 0.219 0.000
S40-S49 Injuries to the shoulder and upper arm
0.781 0.219 0.000
A41.9 Septicaemia, unspecified
0.781 0.219 0.000
V10-V19 Pedal cyclist injured in transport accident
0.780 0.220 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.779 0.221 0.000
M91-M94 Chondropathies
0.778 0.221 0.000
R94.5 Abnormal results of liver function studies
0.778 0.222 0.000
B44 Aspergillosis
0.776 0.224 0.000
H72 Perforation of tympanic membrane
0.775 0.225 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.775 0.225 0.000
Z60.2 Living alone
0.775 0.225 0.000
F34 Persistent mood [affective] disorders
0.772 0.228 0.000
D50.8 Other iron deficiency anaemias
0.771 0.229 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.771 0.229 0.000
C61 Malignant neoplasm of prostate
0.770 0.230 0.000
H66 Suppurative and unspecified otitis media
0.770 0.230 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.770 0.230 0.000
Y43.4 Immunosuppressive agents
0.769 0.231 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.769 0.231 0.000
R00.0 Tachycardia, unspecified
0.767 0.233 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.765 0.235 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.764 0.236 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.763 0.237 0.000
N17-N19 Renal failure
0.762 0.238 0.000
Y52 Agents primarily affecting the cardiovascular system
0.762 0.238 0.000
H61 Other disorders of external ear
0.759 0.241 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.759 0.241 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.758 0.242 0.000
E53 Deficiency of other B group vitamins
0.758 0.242 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.757 0.243 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.757 0.243 0.000
M54.36 Sciatica (Lumbar region)
0.757 0.243 0.000
K29.8 Duodenitis
0.756 0.244 0.000
V40-V49 Car occupant injured in transport accident
0.756 0.244 0.000
M77 Other enthesopathies
0.755 0.245 0.000
Z90.8 Acquired absence of other organs
0.754 0.246 0.000
D70 Agranulocytosis
0.754 0.246 0.000
R56 Convulsions, not elsewhere classified
0.753 0.247 0.000
K26 Duodenal ulcer
0.752 0.248 0.000
K92.1 Melaena
0.750 0.250 0.000
Chapter XXII Codes for special purposes
0.749 0.251 0.000
C67 Malignant neoplasm of bladder
0.749 0.251 0.000
M65-M68 Disorders of synovium and tendon
0.749 0.251 0.000
R60.9 Oedema, unspecified
0.748 0.252 0.000
Z92.0 Personal history of contraception
0.748 0.252 0.000
Y40 Systemic antibiotics
0.747 0.253 0.000
D00-D09 In situ neoplasms
0.747 0.253 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.746 0.254 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.745 0.255 0.000
M50 Cervical disk disorders
0.745 0.255 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.742 0.258 0.000
B37 Candidiasis
0.741 0.259 0.000
K50.0 Crohn's disease of small intestine
0.741 0.259 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.739 0.261 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.738 0.262 0.000
Z94 Transplanted organ and tissue status
0.735 0.265 0.000
A49.0 Staphylococcal infection, unspecified
0.734 0.265 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.734 0.266 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.734 0.266 0.000
F33 Recurrent depressive disorder
0.733 0.267 0.000
M79.1 Myalgia
0.731 0.269 0.000
S10-S19 Injuries to the neck
0.731 0.269 0.000
R50 Fever of unknown origin
0.729 0.271 0.000
F31 Bipolar affective disorder
0.729 0.271 0.000
Z89 Acquired absence of limb
0.729 0.271 0.000
M79.8 Other specified soft tissue disorders
0.729 0.271 0.000
M54.22 Cervicalgia (Cervical region)
0.729 0.271 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.728 0.271 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.728 0.272 0.000
C79 Secondary malignant neoplasm of other sites
0.727 0.273 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.727 0.273 0.000
R41.0 Disorientation, unspecified
0.726 0.274 0.000
G90-G99 Other disorders of the nervous system
0.725 0.275 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.725 0.275 0.000
R49 Voice disturbances
0.724 0.275 0.000
K25 Gastric ulcer
0.724 0.276 0.000
E40-E46 Malnutrition
0.724 0.276 0.000
Z93.5 Cystostomy status
0.724 0.276 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.724 0.276 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.723 0.277 0.000
F80-F89 Disorders of psychological development
0.723 0.277 0.000
H61.0 Perichondritis of external ear
0.721 0.279 0.000
M53 Other dorsopathies, not elsewhere classified
0.721 0.279 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.720 0.280 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.718 0.282 0.000
A41.8 Other specified septicaemia
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.717 0.283 0.000
M75 Shoulder lesions
0.717 0.283 0.000
H65 Nonsuppurative otitis media
0.716 0.284 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.6 Pain in thoracic spine
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.715 0.284 0.000
N18 Chronic renal failure
0.715 0.285 0.000
R60.0 Localised oedema
0.715 0.285 0.000
E87.7 Fluid overload
0.715 0.285 0.000
E27 Other disorders of adrenal gland
0.715 0.285 0.000
R44.3 Hallucinations, unspecified
0.714 0.285 0.000
R07 Pain in throat and chest
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
M54.55 Low back pain (Thoracolumbar region)
0.713 0.287 0.000
M54.54 Low back pain-Thoracic
0.713 0.287 0.000
M54.53 Low back pain-Cervicothoracic
0.713 0.287 0.000
M54.52 Low back pain-Cervical
0.713 0.287 0.000
M54.51 Low back pain-Occipit-atl-axl
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.712 0.288 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.712 0.288 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
K92.9 Disease of digestive system, unspecified
0.711 0.289 0.000
F60 Specific personality disorders
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.710 0.290 0.000
K31.8 Other specified diseases of stomach and duodenum
0.710 0.290 0.000
R52.9 Pain, unspecified
0.709 0.291 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.709 0.291 0.000
R54 Senility
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
Z92.8 Personal history of other medical treatment
0.709 0.291 0.000
M40-M43 Deforming dorsopathies
0.708 0.292 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.707 0.293 0.000
R62 Lack of expected normal physiological development
0.707 0.293 0.000
R57 Shock, not elsewhere classified
0.707 0.293 0.000
R64 Cachexia
0.707 0.293 0.000
R58 Haemorrhage, not elsewhere classified
0.707 0.293 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y57 Other and unspecified drugs and medicaments
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
R46 Symptoms and signs involving appearance and behaviour
0.706 0.294 0.000
R43 Disturbances of smell and taste
0.706 0.294 0.000
K28 Gastrojejunal ulcer
0.706 0.294 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.706 0.294 0.000
M79.70 Fibromyalgia (Multiple sites)
0.705 0.294 0.000
Z84 Family history of other conditions
0.705 0.295 0.000
Z81 Family history of mental and behavioural disorders
0.705 0.295 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.705 0.295 0.000
K31.7 Polyp of stomach and duodenum
0.705 0.295 0.000
K29.3 Chronic superficial gastritis
0.705 0.295 0.000
G62 Other polyneuropathies
0.704 0.296 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
K92.0 Haematemesis
0.704 0.296 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.703 0.297 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.703 0.297 0.000
R21 Rash and other nonspecific skin eruption
0.703 0.297 0.000
E83.4 Disorders of magnesium metabolism
0.703 0.297 0.000
M79.60 Pain in limb (Multiple sites)
0.703 0.297 0.000
M79.69 Pain in limb (Site unspecified)
0.702 0.298 0.000
M79.9 Soft tissue disorder, unspecified
0.702 0.298 0.000
M79.5 Residual foreign body in soft tissue
0.702 0.298 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.702 0.298 0.000
M79.3 Panniculitis, unspecified
0.702 0.298 0.000
M79.2 Neuralgia and neuritis, unspecified
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.701 0.298 0.000
E61 Deficiency of other nutrient elements
0.701 0.299 0.000
F32.1 Moderate depressive episode
0.701 0.299 0.000
E88 Other metabolic disorders
0.700 0.299 0.000
H71 Cholesteatoma of middle ear
0.700 0.300 0.000
R41.3 Other amnesia
0.700 0.300 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.700 0.300 0.000
R61 Hyperhidrosis
0.699 0.301 0.000
M47.8 Other spondylosis
0.699 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.301 0.000
R52.0 Acute pain
0.698 0.302 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.697 0.303 0.000
Z93.1 Gastrostomy status
0.697 0.303 0.000
E55.9 Vitamin D deficiency, unspecified
0.697 0.303 0.000
R45 Symptoms and signs involving emotional state
0.696 0.304 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.696 0.304 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.695 0.305 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.305 0.000
C67.9 Bladder, unspecified
0.693 0.307 0.000
Z92.9 Personal history of medical treatment, unspecified
0.692 0.308 0.000
Z92.5 Personal history of rehabilitation measures
0.692 0.308 0.000
E29 Testicular dysfunction
0.691 0.309 0.000
Y43.9 Primarily systemic agent, unspecified
0.691 0.309 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.691 0.309 0.000
Y43.6 Enzymes, not elsewhere classified
0.691 0.309 0.000
Y43.5 Acidifying and alkalising agents
0.691 0.309 0.000
Y43.2 Antineoplastic natural products
0.691 0.309 0.000
Y43.1 Antineoplastic antimetabolites
0.691 0.309 0.000
Y43.0 Antiallergic and antiemetic drugs
0.691 0.309 0.000
F38 Other mood [affective] disorders
0.691 0.309 0.000
F30 Manic episode
0.691 0.309 0.000
F39 Unspecified mood [affective] disorder
0.691 0.309 0.000
M79.63 Pain in limb (Forearm)
0.690 0.310 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.689 0.311 0.000
F32.0 Mild depressive episode
0.686 0.314 0.000
D68.9 Coagulation defect, unspecified
0.686 0.314 0.000
E28 Ovarian dysfunction
0.686 0.314 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.685 0.315 0.000
R40.1 Stupor
0.685 0.315 0.000
R20 Disturbances of skin sensation
0.685 0.315 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.315 0.000
M46 Other inflammatory spondylopathies
0.684 0.315 0.000
A49.8 Other bacterial infections of unspecified site
0.684 0.316 0.000
R94.4 Abnormal results of kidney function studies
0.684 0.316 0.000
E83.1 Disorders of iron metabolism
0.684 0.316 0.000
N18.9 Chronic renal failure, unspecified
0.683 0.317 0.000
R52.1 Chronic intractable pain
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.682 0.318 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.682 0.318 0.000
M49 Spondylopathies in diseases classified elsewhere
0.681 0.319 0.000
G30-G32 Other degenerative diseases of the nervous system
0.681 0.319 0.000
Z91.6 Personal history of other physical trauma
0.681 0.319 0.000
Y44 Agents primarily affecting blood constituents
0.681 0.319 0.000
A48 Other bacterial diseases, not elsewhere classified
0.681 0.319 0.000
A44 Bartonellosis
0.681 0.319 0.000
A43 Nocardiosis
0.681 0.319 0.000
A42 Actinomycosis
0.681 0.319 0.000
A40 Streptococcal septicaemia
0.681 0.319 0.000
A39 Meningococcal infection
0.681 0.319 0.000
A37 Whooping cough
0.681 0.319 0.000
A36 Diphtheria
0.681 0.319 0.000
A32 Listeriosis
0.681 0.319 0.000
A31 Infection due to other mycobacteria
0.681 0.319 0.000
A30 Leprosy [Hansen's disease]
0.681 0.319 0.000
A46 Erysipelas
0.681 0.319 0.000
A38 Scarlet fever
0.681 0.319 0.000
A35 Other tetanus
0.681 0.319 0.000
A34 Obstetrical tetanus
0.681 0.319 0.000
A33 Tetanus neonatorum
0.681 0.319 0.000
O60-O75 Complications of labour and delivery
0.681 0.319 0.000
M86-M90 Other osteopathies
0.679 0.321 0.000
Z93.6 Other artificial openings of urinary tract status
0.678 0.322 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.677 0.323 0.000
N60-N64 Disorders of breast
0.677 0.323 0.000
C51-C58 Malignant neoplasms of female genital organs
0.676 0.324 0.000
K52 Other non-infective gastro-enteritis and colitis
0.676 0.324 0.000
Z97 Presence of other devices
0.676 0.324 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.675 0.325 0.000
Z93.2 Ileostomy status
0.675 0.325 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.674 0.326 0.000
F41 Other anxiety disorders
0.674 0.326 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.674 0.326 0.000
B15-B19 Viral hepatitis
0.673 0.326 0.000
G95 Other diseases of spinal cord
0.673 0.327 0.000
Z96 Presence of other functional implants
0.673 0.327 0.000
H74 Other disorders of middle ear and mastoid
0.673 0.327 0.000
N40-N51 Diseases of male genital organs
0.672 0.328 0.000
Z88.5 Personal history of allergy to narcotic agent
0.672 0.328 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
M54.39 Sciatica (Site unspecified)
0.671 0.329 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.670 0.330 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.670 0.330 0.000
E85 Amyloidosis
0.669 0.331 0.000
E84 Cystic fibrosis
0.669 0.331 0.000
E79 Disorders of purine and pyrimidine metabolism
0.669 0.331 0.000
E77 Disorders of glycoprotein metabolism
0.669 0.331 0.000
E76 Disorders of glycosaminoglycan metabolism
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
E74 Other disorders of carbohydrate metabolism
0.669 0.331 0.000
E73 Lactose intolerance
0.669 0.331 0.000
E72 Other disorders of amino-acid metabolism
0.669 0.331 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.669 0.331 0.000
E70 Disorders of aromatic amino-acid metabolism
0.669 0.331 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.669 0.331 0.000
K40-K46 Hernia
0.667 0.333 0.000
Z88.0 Personal history of allergy to penicillin
0.667 0.333 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.667 0.333 0.000
W29 Contact with other powered hand tools and household machinery
0.667 0.333 0.000
F32.8 Other depressive episodes
0.665 0.335 0.000
Z93.3 Colostomy status
0.665 0.335 0.000
M84 Disorders of continuity of bone
0.665 0.335 0.000
Z63 Other problems related to primary support group, including family circumstances
0.664 0.336 0.000
E87.5 Hyperkalaemia
0.664 0.336 0.000
M51 Other intervertebral disk disorders
0.664 0.336 0.000
M48.02 Spinal stenosis (Cervical region)
0.663 0.337 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.663 0.337 0.000
K70 Alcoholic liver disease
0.662 0.338 0.000
M71.3 Other bursal cyst
0.662 0.338 0.000
C15-C26 Malignant neoplasms of digestive organs
0.662 0.338 0.000
Z92.3 Personal history of irradiation
0.661 0.339 0.000
T79-T79 Certain early complications of trauma
0.661 0.339 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.660 0.340 0.000
D69 Purpura and other haemorrhagic conditions
0.660 0.340 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.660 0.340 0.000
E87.3 Alkalosis
0.659 0.341 0.000
K51.2 Ulcerative (chronic) proctitis
0.659 0.341 0.000
R68 Other general symptoms and signs
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.658 0.342 0.000
H66.9 Otitis media, unspecified
0.658 0.342 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.658 0.342 0.000
H69 Other disorders of Eustachian tube
0.657 0.343 0.000
Z93.9 Artificial opening status, unspecified
0.657 0.343 0.000
Z93.8 Other artificial opening status
0.657 0.343 0.000
N10-N16 Renal tubulo-interstitial diseases
0.657 0.343 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.656 0.344 0.000
E53.8 Deficiency of other specified B group vitamins
0.656 0.344 0.000
M79.08 Rheumatism, unspecified (Other)
0.655 0.345 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.655 0.345 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.655 0.345 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.655 0.345 0.000
M79.04 Rheumatism, unspecified (Hand)
0.655 0.345 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.655 0.345 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.655 0.345 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.655 0.345 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.655 0.345 0.000
R52.2 Other chronic pain
0.653 0.347 0.000
K51.4 Pseudopolyposis of colon
0.652 0.347 0.000
R47 Speech disturbances, not elsewhere classified
0.652 0.348 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.652 0.348 0.000
Z80 Family history of malignant neoplasm
0.652 0.348 0.000
M54.1 Radiculopathy
0.651 0.349 0.000
M48.06 Spinal stenosis (Lumbar region)
0.651 0.349 0.000
D62 Acute posthaemorrhagic anaemia
0.650 0.350 0.000
R44.0 Auditory hallucinations
0.649 0.351 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.648 0.352 0.000
E87.6 Hypokalaemia
0.647 0.353 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.647 0.353 0.000
R41.2 Retrograde amnesia
0.647 0.353 0.000
R41.1 Anterograde amnesia
0.647 0.353 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.646 0.354 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.646 0.354 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.645 0.355 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.645 0.355 0.000
E63 Other nutritional deficiencies
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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