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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72677506
log Bayes Factor = 17.2748
Chromosome 4   position 99,846,769  (GRCh37) Explore rs72677506 on Ensembl!
Variant rs72677506 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
M19 Other arthrosis
0.995 0.005 0.000
M20 Acquired deformities of fingers and toes
0.994 0.006 0.000
M19.9 Arthrosis, unspecified
0.993 0.007 0.000
M75 Shoulder lesions
0.992 0.008 0.000
I47 Paroxysmal tachycardia
0.987 0.013 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.978 0.022 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.977 0.023 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
I60-I69 Cerebrovascular diseases
0.973 0.027 0.000
I50 Heart failure
0.973 0.027 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.972 0.028 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.969 0.031 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.967 0.033 0.000
M25 Other joint disorders, not elsewhere classified
0.966 0.034 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.966 0.034 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.961 0.039 0.000
I47.2 Ventricular tachycardia
0.960 0.040 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.959 0.041 0.000
M20.4 Other hammer toe(s) (acquired)
0.955 0.045 0.000
Chapter VI Diseases of the nervous system
0.955 0.045 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.954 0.046 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.952 0.048 0.000
M20.2 Hallux rigidus
0.948 0.052 0.000
M50-M54 Other dorsopathies
0.947 0.053 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.946 0.054 0.000
W00-W19 Falls
0.946 0.054 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.945 0.055 0.000
I42 Cardiomyopathy
0.939 0.061 0.000
R26 Abnormalities of gait and mobility
0.938 0.062 0.000
F10.1 Harmful use
0.937 0.063 0.000
M75.0 Adhesive capsulitis of shoulder
0.936 0.064 0.000
I84 Haemorrhoids
0.934 0.066 0.000
I50.0 Congestive heart failure
0.933 0.067 0.000
M25.7 Osteophyte
0.932 0.068 0.000
Y83.6 Removal of other organ (partial) (total)
0.931 0.069 0.000
S20-S29 Injuries to the thorax
0.931 0.069 0.000
M75.1 Rotator cuff syndrome
0.930 0.070 0.000
S00 Superficial injury of head
0.927 0.073 0.000
R47-R49 Symptoms and signs involving speech and voice
0.913 0.087 0.000
I46 Cardiac arrest
0.910 0.090 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.909 0.091 0.000
I44 Atrioventricular and left bundle-branch block
0.907 0.093 0.000
I84.9 Unspecified haemorrhoids without complication
0.904 0.096 0.000
M65-M68 Disorders of synovium and tendon
0.898 0.102 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.897 0.103 0.000
M51 Other intervertebral disk disorders
0.896 0.104 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.892 0.108 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.892 0.108 0.000
W19 Unspecified fall
0.890 0.110 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.884 0.116 0.000
I47.1 Supraventricular tachycardia
0.883 0.117 0.000
M75.5 Bursitis of shoulder
0.883 0.117 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.872 0.128 0.000
G90-G99 Other disorders of the nervous system
0.870 0.130 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.869 0.131 0.000
W20-W49 Exposure to inanimate mechanical forces
0.869 0.131 0.000
F10.2 Dependence syndrome
0.868 0.132 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.860 0.140 0.000
M45-M49 Spondylopathies
0.857 0.143 0.000
R27 Other lack of coordination
0.851 0.149 0.000
F10.3 Withdrawal state
0.850 0.150 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.850 0.150 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.848 0.152 0.000
I46.0 Cardiac arrest with successful resuscitation
0.848 0.152 0.000
M23 Internal derangement of knee
0.847 0.153 0.000
M19.0 Primary arthrosis of other joints
0.847 0.153 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.845 0.155 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.843 0.157 0.000
I61 Intracerebral haemorrhage
0.842 0.158 0.000
S90-S99 Injuries to the ankle and foot
0.841 0.159 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.840 0.160 0.000
G30-G32 Other degenerative diseases of the nervous system
0.840 0.160 0.000
Y83.8 Other surgical procedures
0.839 0.161 0.000
Chapter I Certain infectious and parasitic diseases
0.839 0.161 0.000
M25.77 Osteophyte (Ankle and foot)
0.837 0.163 0.000
M75.4 Impingement syndrome of shoulder
0.836 0.164 0.000
I71 Aortic aneurysm and dissection
0.834 0.166 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.834 0.166 0.000
I45 Other conduction disorders
0.829 0.171 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.829 0.171 0.000
S40-S49 Injuries to the shoulder and upper arm
0.829 0.171 0.000
M18 Arthrosis of first carpometacarpal joint
0.828 0.172 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.828 0.172 0.000
M25.76 Osteophyte (Lower leg)
0.826 0.174 0.000
I42.9 Cardiomyopathy, unspecified
0.824 0.176 0.000
R47 Speech disturbances, not elsewhere classified
0.822 0.178 0.000
I44.0 Atrioventricular block, first degree
0.820 0.180 0.000
I50.9 Heart failure, unspecified
0.819 0.181 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.819 0.181 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.818 0.182 0.000
S00.8 Superficial injury of other parts of head
0.817 0.183 0.000
F10.0 Acute intoxication
0.816 0.184 0.000
I86 Varicose veins of other sites
0.816 0.184 0.000
S20 Superficial injury of thorax
0.815 0.185 0.000
I67 Other cerebrovascular diseases
0.815 0.185 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.814 0.186 0.000
Q21 Congenital malformations of cardiac septa
0.814 0.186 0.000
W19.9 Unspecified place
0.813 0.187 0.000
L50-L54 Urticaria and erythema
0.813 0.187 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.812 0.188 0.000
I42.0 Dilated cardiomyopathy
0.812 0.188 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.808 0.192 0.000
S70-S79 Injuries to the hip and thigh
0.807 0.193 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.807 0.193 0.000
M20.1 Hallux valgus (acquired)
0.802 0.198 0.000
M65 Synovitis and tenosynovitis
0.800 0.200 0.000
T66-T78 Other and unspecified effects of external causes
0.800 0.200 0.000
M86-M90 Other osteopathies
0.799 0.201 0.000
I70 Atherosclerosis
0.798 0.202 0.000
S60-S69 Injuries to the wrist and hand
0.797 0.203 0.000
I60 Subarachnoid haemorrhage
0.796 0.204 0.000
I74 Arterial embolism and thrombosis
0.793 0.206 0.000
S06 Intracranial injury
0.793 0.207 0.000
M54 Dorsalgia
0.790 0.210 0.000
M19.98 Arthrosis, unspecified (Other)
0.790 0.210 0.000
S00.0 Superficial injury of scalp
0.790 0.210 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.789 0.211 0.000
Chapter VIII Diseases of the ear and mastoid process
0.788 0.212 0.000
I87 Other disorders of veins
0.788 0.212 0.000
M20.3 Other deformity of hallux (acquired)
0.787 0.213 0.000
A30-A49 Other bacterial diseases
0.786 0.214 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.784 0.216 0.000
T90 Sequelae of injuries of head
0.783 0.217 0.000
I69 Sequelae of cerebrovascular disease
0.783 0.217 0.000
R49 Voice disturbances
0.780 0.220 0.000
L60-L75 Disorders of skin appendages
0.778 0.222 0.000
I84.4 External haemorrhoids with other complications
0.778 0.222 0.000
I85 Oesophageal varices
0.777 0.223 0.000
M19.1 Posttraumatic arthrosis of other joints
0.776 0.224 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.774 0.226 0.000
M71 Other bursopathies
0.773 0.226 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.771 0.229 0.000
L40-L45 Papulosquamous disorders
0.771 0.229 0.000
V20-V29 Motorcycle rider injured in transport accident
0.769 0.231 0.000
T79-T79 Certain early complications of trauma
0.769 0.231 0.000
M51.2 Other specified intervertebral disk displacement
0.766 0.234 0.000
I83 Varicose veins of lower extremities
0.766 0.234 0.000
W19.2 School, other institution and public administrative area
0.766 0.234 0.000
S09 Other and unspecified injuries of head
0.765 0.235 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.764 0.236 0.000
Q21.1 Atrial septal defect
0.763 0.237 0.000
M25.8 Other specified joint disorders
0.763 0.237 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.762 0.237 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.762 0.238 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.760 0.240 0.000
R42 Dizziness and giddiness
0.759 0.241 0.000
M25.78 Osteophyte (Other)
0.759 0.241 0.000
S02 Fracture of skull and facial bones
0.757 0.243 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.755 0.245 0.000
W08 Fall involving other furniture
0.753 0.247 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.753 0.247 0.000
A41 Other septicaemia
0.753 0.247 0.000
M79.6 Pain in limb
0.752 0.248 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.751 0.248 0.000
I05-I09 Chronic rheumatic heart diseases
0.751 0.249 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.751 0.249 0.000
R25 Abnormal involuntary movements
0.750 0.250 0.000
S01 Open wound of head
0.749 0.251 0.000
I73 Other peripheral vascular diseases
0.749 0.251 0.000
Chapter XXII Codes for special purposes
0.749 0.251 0.000
S00.1 Contusion of eyelid and periocular area
0.749 0.251 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.745 0.254 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.744 0.256 0.000
I84.1 Internal haemorrhoids with other complications
0.744 0.256 0.000
Q50-Q56 Congenital malformations of genital organs
0.743 0.257 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.742 0.258 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.741 0.259 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
Q28 Other congenital malformations of circulatory system
0.739 0.261 0.000
M72 Fibroblastic disorders
0.739 0.261 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.738 0.262 0.000
S27 Injury of other and unspecified intrathoracic organs
0.737 0.263 0.000
I63 Cerebral infarction
0.736 0.264 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.736 0.264 0.000
R82 Other abnormal findings in urine
0.736 0.264 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.735 0.265 0.000
I50.1 Left ventricular failure
0.735 0.265 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.735 0.265 0.000
I44.2 Atrioventricular block, complete
0.735 0.265 0.000
L91 Hypertrophic disorders of skin
0.734 0.266 0.000
I30 Acute pericarditis
0.732 0.268 0.000
I42.2 Other hypertrophic cardiomyopathy
0.731 0.269 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.730 0.270 0.000
M25.71 Osteophyte (Shoulder region)
0.730 0.270 0.000
V10-V19 Pedal cyclist injured in transport accident
0.729 0.270 0.000
M47 Spondylosis
0.729 0.271 0.000
Q60-Q64 Congenital malformations of the urinary system
0.728 0.272 0.000
I84.5 External haemorrhoids without complication
0.728 0.272 0.000
G61 Inflammatory polyneuropathy
0.728 0.272 0.000
V80-V89 Other land transport accidents
0.728 0.272 0.000
E65-E68 Obesity and other hyperalimentation
0.728 0.272 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.728 0.272 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.727 0.273 0.000
M34 Systemic sclerosis
0.727 0.273 0.000
M25.4 Effusion of joint
0.727 0.273 0.000
R27.8 Other and unspecified lack of coordination
0.724 0.276 0.000
R47.8 Other and unspecified speech disturbances
0.723 0.277 0.000
W06 Fall involving bed
0.723 0.277 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.721 0.279 0.000
Y83.3 Surgical operation with formation of external stoma
0.721 0.279 0.000
I84.0 Internal thrombosed haemorrhoids
0.721 0.279 0.000
M80-M85 Disorders of bone density and structure
0.720 0.279 0.000
R26.0 Ataxic gait
0.720 0.280 0.000
W29 Contact with other powered hand tools and household machinery
0.719 0.281 0.000
I45.3 Trifascicular block
0.718 0.282 0.000
M23.3 Other meniscus derangements
0.718 0.282 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.718 0.282 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
M21 Other acquired deformities of limbs
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
I44.7 Left bundle-branch block, unspecified
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.715 0.285 0.000
M15 Polyarthrosis
0.714 0.286 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
G81 Hemiplegia
0.713 0.287 0.000
M19.8 Other specified arthrosis
0.713 0.287 0.000
M19.2 Other secondary arthrosis
0.713 0.287 0.000
S00.3 Superficial injury of nose
0.713 0.287 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.712 0.288 0.000
M75.8 Other shoulder lesions
0.712 0.288 0.000
M75.9 Shoulder lesion, unspecified
0.712 0.288 0.000
M20.5 Other deformities of toe(s) (acquired)
0.711 0.289 0.000
M25.74 Osteophyte (Hand)
0.711 0.289 0.000
A41.9 Septicaemia, unspecified
0.710 0.290 0.000
M67 Other disorders of synovium and tendon
0.710 0.290 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.709 0.291 0.000
I47.0 Reentry ventricular arrhythmia
0.708 0.292 0.000
S29 Other and unspecified injuries of thorax
0.707 0.293 0.000
L20-L30 Dermatitis and eczema
0.707 0.293 0.000
G62 Other polyneuropathies
0.707 0.293 0.000
G95 Other diseases of spinal cord
0.706 0.294 0.000
R40 Somnolence, stupor and coma
0.706 0.294 0.000
I33 Acute and subacute endocarditis
0.705 0.295 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.705 0.295 0.000
H90-H95 Other disorders of ear
0.705 0.295 0.000
M53 Other dorsopathies, not elsewhere classified
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
I62 Other nontraumatic intracranial haemorrhage
0.701 0.299 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.701 0.299 0.000
I88 Nonspecific lymphadenitis
0.701 0.299 0.000
I82 Other venous embolism and thrombosis
0.701 0.299 0.000
I81 Portal vein thrombosis
0.701 0.299 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.698 0.302 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.698 0.302 0.000
T98 Sequelae of other and unspecified effects of external causes
0.696 0.304 0.000
L10-L14 Bullous disorders
0.695 0.305 0.000
I78 Diseases of capillaries
0.695 0.305 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.693 0.307 0.000
F70-F79 Mental retardation
0.693 0.307 0.000
F60-F69 Disorders of adult personality and behaviour
0.693 0.307 0.000
M25.9 Joint disorder, unspecified
0.693 0.307 0.000
M25.3 Other instability of joint
0.693 0.307 0.000
M25.2 Flail joint
0.693 0.307 0.000
M25.1 Fistula of joint
0.693 0.307 0.000
M25.0 Haemarthrosis
0.693 0.307 0.000
L50 Urticaria
0.692 0.308 0.000
T81 Complications of procedures, not elsewhere classified
0.691 0.309 0.000
I84.6 Residual haemorrhoidal skin tags
0.691 0.309 0.000
R27.0 Ataxia, unspecified
0.690 0.309 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.689 0.311 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.689 0.311 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.689 0.311 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.689 0.311 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.689 0.311 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.689 0.311 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.689 0.311 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.689 0.311 0.000
F11 Mental and behavioural disorders due to use of opioids
0.689 0.311 0.000
R80 Isolated proteinuria
0.688 0.312 0.000
F10.9 Unspecified mental and behavioural disorder
0.688 0.312 0.000
F10.8 Other mental and behavioural disorders
0.688 0.312 0.000
F10.7 Residual and late-onset psychotic disorder
0.688 0.312 0.000
F10.6 Amnesic syndrome
0.688 0.312 0.000
F10.5 Psychotic disorder
0.688 0.312 0.000
F10.4 Withdrawal state with delirium
0.688 0.312 0.000
R81 Glycosuria
0.687 0.312 0.000
M75.2 Bicipital tendinitis
0.687 0.313 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.687 0.313 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
R49.0 Dysphonia
0.684 0.316 0.000
Y83.5 Amputation of limb(s)
0.684 0.316 0.000
Y83.0 Surgical operation with transplant of whole organ
0.684 0.316 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.683 0.317 0.000
T18 Foreign body in alimentary tract
0.683 0.317 0.000
R47.0 Dysphasia and aphasia
0.683 0.317 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.682 0.318 0.000
I72 Other aneurysm
0.682 0.318 0.000
T17 Foreign body in respiratory tract
0.682 0.318 0.000
M40-M43 Deforming dorsopathies
0.682 0.318 0.000
I67.8 Other specified cerebrovascular diseases
0.681 0.319 0.000
M23.4 Loose body in knee
0.680 0.320 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.680 0.320 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.680 0.320 0.000
S91 Open wound of ankle and foot
0.680 0.320 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.679 0.321 0.000
W10 Fall on and from stairs and steps
0.678 0.321 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.678 0.321 0.000
Q80-Q89 Other congenital malformations
0.678 0.321 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.678 0.321 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.678 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.678 0.321 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.678 0.321 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.678 0.321 0.000
Q00-Q07 Congenital malformations of the nervous system
0.678 0.321 0.000
W18 Other fall on same level
0.678 0.322 0.000
W17 Other fall from one level to another
0.678 0.322 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.678 0.322 0.000
W15 Fall from cliff
0.678 0.322 0.000
W14 Fall from tree
0.678 0.322 0.000
W13 Fall from, out of or through building or structure
0.678 0.322 0.000
W12 Fall on and from scaffolding
0.678 0.322 0.000
W11 Fall on and from ladder
0.678 0.322 0.000
W09 Fall involving playground equipment
0.678 0.322 0.000
W05 Fall involving wheelchair
0.678 0.322 0.000
W04 Fall while being carried or supported by other persons
0.678 0.322 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.678 0.322 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.678 0.322 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.678 0.322 0.000
W00 Fall on same level involving ice and snow
0.678 0.322 0.000
L81 Other disorders of pigmentation
0.678 0.322 0.000
G91 Hydrocephalus
0.677 0.323 0.000
T86 Failure and rejection of transplanted organs and tissues
0.677 0.323 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.677 0.323 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.677 0.323 0.000
L89 Decubitus ulcer
0.674 0.326 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.674 0.326 0.000
I42.8 Other cardiomyopathies
0.673 0.326 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.673 0.326 0.000
I42.6 Alcoholic cardiomyopathy
0.673 0.326 0.000
I42.5 Other restrictive cardiomyopathy
0.673 0.326 0.000
I42.4 Endocardial fibroelastosis
0.673 0.326 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.673 0.326 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.673 0.326 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.673 0.327 0.000
T93 Sequelae of injuries of lower limb
0.673 0.327 0.000
S90 Superficial injury of ankle and foot
0.672 0.328 0.000
R26.3 Immobility
0.672 0.328 0.000
R26.1 Paralytic gait
0.672 0.328 0.000
M45 Ankylosing spondylitis
0.672 0.328 0.000
G70-G73 Diseases of myoneural junction and muscle
0.671 0.328 0.000
S80-S89 Injuries to the knee and lower leg
0.671 0.328 0.000
T90.5 Sequelae of intracranial injury
0.671 0.329 0.000
I34 Nonrheumatic mitral valve disorders
0.671 0.329 0.000
M51.9 Intervertebral disk disorder, unspecified
0.671 0.329 0.000
W44 Foreign body entering into or through eye or natural orifice
0.670 0.330 0.000
M54.9 Dorsalgia, unspecified
0.669 0.331 0.000
I86.1 Scrotal varices
0.669 0.331 0.000
M25.79 Osteophyte (Site unspecified)
0.668 0.332 0.000
M25.73 Osteophyte (Forearm)
0.668 0.332 0.000
M25.72 Osteophyte (Upper arm)
0.668 0.332 0.000
M25.70 Osteophyte (Multiple sites)
0.668 0.332 0.000
E10-E14 Diabetes mellitus
0.668 0.332 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.667 0.332 0.000
S26 Injury of heart
0.667 0.332 0.000
S25 Injury of blood vessels of thorax
0.667 0.332 0.000
S24 Injury of nerves and spinal cord at thorax level
0.667 0.332 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.667 0.332 0.000
S21 Open wound of thorax
0.667 0.332 0.000
M79.1 Myalgia
0.667 0.333 0.000
S40 Superficial injury of shoulder and upper arm
0.666 0.334 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.666 0.334 0.000
Y86 Sequelae of other accidents
0.666 0.334 0.000
R29.6 Tendency to fall, not elsewhere classified
0.666 0.334 0.000
E20-E35 Disorders of other endocrine glands
0.666 0.334 0.000
G30 Alzheimer's disease
0.665 0.335 0.000
G96 Other disorders of central nervous system
0.665 0.335 0.000
M79.0 Rheumatism, unspecified
0.665 0.335 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.665 0.335 0.000
S00.7 Multiple superficial injuries of head
0.665 0.335 0.000
S00.5 Superficial injury of lip and oral cavity
0.665 0.335 0.000
S00.4 Superficial injury of ear
0.665 0.335 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.665 0.335 0.000
L57.0 Actinic keratosis
0.664 0.336 0.000
M24 Other specific joint derangements
0.663 0.336 0.000
M23.8 Other internal derangements of knee
0.663 0.337 0.000
M77 Other enthesopathies
0.663 0.337 0.000
I45.9 Conduction disorder, unspecified
0.663 0.337 0.000
W25 Contact with sharp glass
0.663 0.337 0.000
E66 Obesity
0.662 0.337 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.662 0.338 0.000
M23.5 Chronic instability of knee
0.662 0.338 0.000
S70 Superficial injury of hip and thigh
0.661 0.339 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.660 0.340 0.000
T92 Sequelae of injuries of upper limb
0.660 0.340 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.659 0.341 0.000
G93 Other disorders of brain
0.658 0.342 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.658 0.342 0.000
I67.1 Cerebral aneurysm, nonruptured
0.657 0.343 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.657 0.343 0.000
L73 Other follicular disorders
0.654 0.345 0.000
Y88 Sequelae of surgical and medical care as external cause
0.654 0.346 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.654 0.346 0.000
X60-X84 Intentional self-harm
0.654 0.346 0.000
F99-F99 Unspecified mental disorder
0.654 0.346 0.000
I46.1 Sudden cardiac death, so described
0.652 0.347 0.000
Y83.9 Surgical procedure, unspecified
0.652 0.347 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.651 0.349 0.000
I44.6 Other and unspecified fascicular block
0.650 0.350 0.000
I44.5 Left posterior fascicular block
0.650 0.350 0.000
I44.4 Left anterior fascicular block
0.650 0.350 0.000
I44.3 Other and unspecified atrioventricular block
0.650 0.350 0.000
S42 Fracture of shoulder and upper arm
0.650 0.350 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.650 0.350 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.650 0.350 0.000
M35 Other systemic involvement of connective tissue
0.649 0.351 0.000
S61 Open wound of wrist and hand
0.649 0.351 0.000
I35 Nonrheumatic aortic valve disorders
0.648 0.352 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.647 0.353 0.000
M54.5 Low back pain
0.647 0.353 0.000
G80 Infantile cerebral palsy
0.647 0.353 0.000
I46.9 Cardiac arrest, unspecified
0.645 0.355 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.644 0.356 0.000
M66 Spontaneous rupture of synovium and tendon
0.644 0.356 0.000
W07 Fall involving chair
0.644 0.356 0.000
M48 Other spondylopathies
0.644 0.356 0.000
T95 Sequelae of burns, corrosions and frostbite
0.643 0.357 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.643 0.357 0.000
T91 Sequelae of injuries of neck and trunk
0.643 0.357 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.643 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.643 0.357 0.000
M19.94 Arthrosis, unspecified (Hand)
0.642 0.357 0.000
W22 Striking against or struck by other objects
0.642 0.357 0.000
M51.3 Other specified intervertebral disk degeneration
0.642 0.358 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.642 0.358 0.000
M51.8 Other specified intervertebral disk disorders
0.642 0.358 0.000
M51.4 Schmorl's nodes
0.642 0.358 0.000
H90 Conductive and sensorineural hearing loss
0.642 0.358 0.000
T87 Complications peculiar to reattachment and amputation
0.640 0.360 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.640 0.360 0.000
T68 Hypothermia
0.639 0.361 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.639 0.361 0.000
R46 Symptoms and signs involving appearance and behaviour
0.639 0.361 0.000
R43 Disturbances of smell and taste
0.639 0.361 0.000
M70.6 Trochanteric bursitis
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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