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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72704010
log Bayes Factor = 16.7236
Chromosome 1   position 169,383,980  (GRCh37) Explore rs72704010 on Ensembl!
Variant rs72704010 is part of Cluster X0134

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.988 0.012 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.981 0.019 0.000
M05-M14 Inflammatory polyarthropathies
0.980 0.020 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.976 0.024 0.000
I24 Other acute ischaemic heart diseases
0.976 0.024 0.000
E78.0 Pure hypercholesterolaemia
0.975 0.025 0.000
K81 Cholecystitis
0.974 0.026 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.974 0.026 0.000
E70-E90 Metabolic disorders
0.973 0.027 0.000
M45-M49 Spondylopathies
0.972 0.028 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.972 0.028 0.000
I25.1 Atherosclerotic heart disease
0.970 0.030 0.000
F30-F39 Mood [affective] disorders
0.969 0.031 0.000
M06 Other rheumatoid arthritis
0.967 0.033 0.000
Chapter II Neoplasms
0.966 0.034 0.000
K08 Other disorders of teeth and supporting structures
0.964 0.036 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.964 0.036 0.000
K81.1 Chronic cholecystitis
0.963 0.037 0.000
I60-I69 Cerebrovascular diseases
0.961 0.039 0.000
I95 Hypotension
0.958 0.042 0.000
Chapter I Certain infectious and parasitic diseases
0.956 0.044 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.955 0.045 0.000
I24.8 Other forms of acute ischaemic heart disease
0.953 0.047 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.952 0.048 0.000
M06.9 Rheumatoid arthritis, unspecified
0.952 0.048 0.000
K86 Other diseases of pancreas
0.944 0.056 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.944 0.056 0.000
C79 Secondary malignant neoplasm of other sites
0.943 0.057 0.000
M48 Other spondylopathies
0.942 0.058 0.000
C34 Malignant neoplasm of bronchus and lung
0.941 0.059 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.929 0.071 0.000
T39.1 4-Aminophenol derivatives
0.929 0.071 0.000
E20-E35 Disorders of other endocrine glands
0.926 0.074 0.000
A30-A49 Other bacterial diseases
0.924 0.076 0.000
M48.0 Spinal stenosis
0.920 0.080 0.000
K04 Diseases of pulp and periapical tissues
0.919 0.081 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.918 0.082 0.000
I95.2 Hypotension due to drugs
0.913 0.087 0.000
Y52 Agents primarily affecting the cardiovascular system
0.912 0.088 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.906 0.094 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.906 0.094 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.906 0.094 0.000
F41 Other anxiety disorders
0.906 0.094 0.000
K04.5 Chronic apical periodontitis
0.900 0.100 0.000
M70-M79 Other soft tissue disorders
0.893 0.107 0.000
F32 Depressive episode
0.891 0.109 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.891 0.109 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.890 0.110 0.000
S40-S49 Injuries to the shoulder and upper arm
0.888 0.112 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.888 0.112 0.000
I30-I52 Other forms of heart disease
0.883 0.117 0.000
C34.1 Upper lobe, bronchus or lung
0.882 0.118 0.000
C34.9 Bronchus or lung, unspecified
0.881 0.119 0.000
F43 Reaction to severe stress, and adjustment disorders
0.877 0.123 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.875 0.125 0.000
F60-F69 Disorders of adult personality and behaviour
0.871 0.129 0.000
K86.3 Pseudocyst of pancreas
0.869 0.131 0.000
K35-K38 Diseases of appendix
0.867 0.133 0.000
Chapter VI Diseases of the nervous system
0.867 0.133 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.865 0.135 0.000
M48.02 Spinal stenosis (Cervical region)
0.864 0.136 0.000
I51 Complications and ill-defined descriptions of heart disease
0.862 0.138 0.000
M07 Psoriatic and enteropathic arthropathies
0.862 0.138 0.000
M48.06 Spinal stenosis (Lumbar region)
0.861 0.139 0.000
I95.9 Hypotension, unspecified
0.860 0.140 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.859 0.141 0.000
B25-B34 Other viral diseases
0.856 0.144 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.853 0.147 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.852 0.148 0.000
Chapter VIII Diseases of the ear and mastoid process
0.852 0.148 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.850 0.150 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.847 0.153 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.844 0.156 0.000
I51.8 Other ill-defined heart diseases
0.843 0.157 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.840 0.160 0.000
I25.2 Old myocardial infarction
0.839 0.161 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.836 0.164 0.000
F33 Recurrent depressive disorder
0.835 0.165 0.000
A41 Other septicaemia
0.833 0.167 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.833 0.167 0.000
M47 Spondylosis
0.828 0.172 0.000
M50-M54 Other dorsopathies
0.827 0.173 0.000
C78.0 Secondary malignant neoplasm of lung
0.825 0.175 0.000
C78.7 Secondary malignant neoplasm of liver
0.824 0.176 0.000
A49 Bacterial infection of unspecified site
0.823 0.177 0.000
F31 Bipolar affective disorder
0.821 0.179 0.000
T66-T78 Other and unspecified effects of external causes
0.820 0.180 0.000
K11 Diseases of salivary glands
0.814 0.186 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
K65-K67 Diseases of peritoneum
0.811 0.189 0.000
I62 Other nontraumatic intracranial haemorrhage
0.810 0.190 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.808 0.192 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.807 0.193 0.000
I21 Acute myocardial infarction
0.806 0.194 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.806 0.194 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.805 0.195 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.804 0.196 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.803 0.197 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.803 0.197 0.000
M65-M68 Disorders of synovium and tendon
0.802 0.198 0.000
I20 Angina pectoris
0.800 0.200 0.000
F41.2 Mixed anxiety and depressive disorder
0.800 0.200 0.000
I95.1 Orthostatic hypotension
0.799 0.201 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.799 0.201 0.000
I34 Nonrheumatic mitral valve disorders
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.796 0.204 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.795 0.205 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.794 0.206 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.793 0.207 0.000
I22 Subsequent myocardial infarction
0.792 0.208 0.000
Chapter VII Diseases of the eye and adnexa
0.792 0.208 0.000
F43.2 Adjustment disorders
0.791 0.209 0.000
I69 Sequelae of cerebrovascular disease
0.790 0.210 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.789 0.211 0.000
K13 Other diseases of lip and oral mucosa
0.789 0.211 0.000
G90-G99 Other disorders of the nervous system
0.789 0.211 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.787 0.213 0.000
C34.3 Lower lobe, bronchus or lung
0.785 0.215 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.785 0.215 0.000
E78.1 Pure hyperglyceridaemia
0.785 0.215 0.000
T79-T79 Certain early complications of trauma
0.784 0.216 0.000
B34 Viral infection of unspecified site
0.784 0.216 0.000
K37 Unspecified appendicitis
0.784 0.216 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.783 0.217 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.782 0.218 0.000
M54 Dorsalgia
0.780 0.220 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.780 0.220 0.000
F60 Specific personality disorders
0.780 0.220 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.779 0.221 0.000
K83 Other diseases of biliary tract
0.778 0.222 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.777 0.223 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.777 0.223 0.000
M07.3 Other psoriatic arthropathies
0.776 0.224 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.776 0.224 0.000
M80-M85 Disorders of bone density and structure
0.775 0.225 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.775 0.225 0.000
F32.1 Moderate depressive episode
0.775 0.225 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.774 0.226 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.773 0.227 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.773 0.227 0.000
X60-X84 Intentional self-harm
0.771 0.228 0.000
M40-M43 Deforming dorsopathies
0.770 0.230 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.770 0.230 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.767 0.233 0.000
M60-M63 Disorders of muscles
0.767 0.233 0.000
A40 Streptococcal septicaemia
0.767 0.233 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.766 0.234 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.766 0.234 0.000
M79.8 Other specified soft tissue disorders
0.764 0.236 0.000
K50-K52 Noninfective enteritis and colitis
0.764 0.236 0.000
S20-S29 Injuries to the thorax
0.763 0.237 0.000
M91-M94 Chondropathies
0.763 0.237 0.000
K86.1 Other chronic pancreatitis
0.763 0.237 0.000
Y85 Sequelae of transport accidents
0.762 0.238 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.760 0.240 0.000
M00-M03 Infectious arthropathies
0.760 0.240 0.000
F80-F89 Disorders of psychological development
0.760 0.240 0.000
F41.9 Anxiety disorder, unspecified
0.760 0.240 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.758 0.242 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.758 0.242 0.000
E78.4 Other hyperlipidaemia
0.756 0.244 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.756 0.244 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.755 0.245 0.000
M06.4 Inflammatory polyarthropathy
0.754 0.245 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.754 0.246 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.754 0.246 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.754 0.246 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.247 0.000
V10-V19 Pedal cyclist injured in transport accident
0.753 0.247 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.750 0.250 0.000
C80 Malignant neoplasm without specification of site
0.750 0.250 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.750 0.250 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.750 0.250 0.000
E78.8 Other disorders of lipoprotein metabolism
0.749 0.250 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.749 0.251 0.000
E22 Hyperfunction of pituitary gland
0.748 0.252 0.000
I63 Cerebral infarction
0.748 0.252 0.000
K86.2 Cyst of pancreas
0.748 0.252 0.000
W50-W64 Exposure to animate mechanical forces
0.747 0.253 0.000
E23 Hypofunction and other disorders of pituitary gland
0.747 0.253 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.746 0.254 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.746 0.254 0.000
M06.3 Rheumatoid nodule
0.745 0.255 0.000
M54.5 Low back pain
0.745 0.255 0.000
E29 Testicular dysfunction
0.742 0.258 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.741 0.259 0.000
D80-D89 Certain disorders involving the immune mechanism
0.740 0.260 0.000
S90-S99 Injuries to the ankle and foot
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.738 0.262 0.000
K70-K77 Diseases of liver
0.737 0.263 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.734 0.266 0.000
C32 Malignant neoplasm of larynx
0.732 0.267 0.000
K11.9 Disease of salivary gland, unspecified
0.732 0.268 0.000
M05 Seropositive rheumatoid arthritis
0.732 0.268 0.000
C77.9 Lymph node, unspecified
0.732 0.268 0.000
K80 Cholelithiasis
0.732 0.268 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
E88 Other metabolic disorders
0.730 0.270 0.000
T43.2 Other and unspecified antidepressants
0.729 0.271 0.000
I47 Paroxysmal tachycardia
0.726 0.274 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.725 0.275 0.000
C79.2 Secondary malignant neoplasm of skin
0.724 0.276 0.000
F99-F99 Unspecified mental disorder
0.724 0.276 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.723 0.277 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.723 0.277 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
Chapter XXI Factors influencing health status and contact with health services
0.722 0.278 0.000
H43-H45 Disorders of vitreous body and globe
0.721 0.279 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.721 0.279 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.721 0.279 0.000
E28 Ovarian dysfunction
0.720 0.280 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.719 0.281 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.719 0.281 0.000
T92 Sequelae of injuries of upper limb
0.719 0.281 0.000
K10 Other diseases of jaws
0.718 0.282 0.000
B65-B83 Helminthiases
0.717 0.282 0.000
I20.0 Unstable angina
0.717 0.283 0.000
C34.2 Middle lobe, bronchus or lung
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
K12 Stomatitis and related lesions
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.284 0.000
F70-F79 Mental retardation
0.715 0.284 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.715 0.285 0.000
F43.1 Posttraumatic stress disorder
0.715 0.285 0.000
G81 Hemiplegia
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
H80-H83 Diseases of inner ear
0.712 0.288 0.000
E27 Other disorders of adrenal gland
0.712 0.288 0.000
B34.9 Viral infection, unspecified
0.712 0.288 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.711 0.289 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.711 0.289 0.000
T91 Sequelae of injuries of neck and trunk
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.289 0.000
Y10-Y34 Event of undetermined intent
0.710 0.289 0.000
Y00-Y09 Assault
0.710 0.289 0.000
X85-X99 Assault
0.710 0.289 0.000
X50-X57 Overexertion, travel and privation
0.710 0.289 0.000
X30-X39 Exposure to forces of nature
0.710 0.289 0.000
X10-X19 Contact with heat and hot substances
0.710 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.289 0.000
W75-W84 Other accidental threats to breathing
0.710 0.289 0.000
W65-W74 Accidental drowning and submersion
0.710 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.289 0.000
V95-V97 Air and space transport accidents
0.710 0.289 0.000
V90-V94 Water transport accidents
0.710 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.289 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.709 0.291 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.709 0.291 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.709 0.291 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.708 0.291 0.000
T39.4 Antirheumatics, not elsewhere classified
0.708 0.291 0.000
T39.2 Pyrazolone derivatives
0.708 0.291 0.000
H90-H95 Other disorders of ear
0.708 0.292 0.000
K03 Other diseases of hard tissues of teeth
0.708 0.292 0.000
K00 Disorders of tooth development and eruption
0.708 0.292 0.000
M06.0 Seronegative rheumatoid arthritis
0.707 0.293 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.707 0.293 0.000
K81.0 Acute cholecystitis
0.706 0.294 0.000
W00-W19 Falls
0.706 0.294 0.000
E50-E64 Other nutritional deficiencies
0.704 0.296 0.000
K65 Peritonitis
0.703 0.296 0.000
M14 Arthropathies in other diseases classified elsewhere
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.702 0.298 0.000
Y45.0 Opioids and related analgesics
0.702 0.298 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.702 0.298 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.701 0.299 0.000
K09 Cysts of oral region, not elsewhere classified
0.700 0.300 0.000
K04.6 Periapical abscess with sinus
0.700 0.300 0.000
F17.2 Dependence syndrome
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
Y59 Other and unspecified vaccines and biological substances
0.700 0.300 0.000
Y58 Bacterial vaccines
0.700 0.300 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.700 0.300 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.700 0.300 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.700 0.300 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
Y48 Anaesthetics and therapeutic gases
0.700 0.300 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.700 0.300 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.700 0.300 0.000
I24.1 Dressler's syndrome
0.699 0.300 0.000
S32 Fracture of lumbar spine and pelvis
0.699 0.301 0.000
K81.8 Other cholecystitis
0.698 0.302 0.000
E78.6 Lipoprotein deficiency
0.698 0.302 0.000
E78.3 Hyperchylomicronaemia
0.698 0.302 0.000
D50-D53 Nutritional anaemias
0.698 0.302 0.000
B99-B99 Other infectious diseases
0.698 0.302 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.698 0.302 0.000
E85 Amyloidosis
0.698 0.302 0.000
E84 Cystic fibrosis
0.698 0.302 0.000
E79 Disorders of purine and pyrimidine metabolism
0.698 0.302 0.000
E77 Disorders of glycoprotein metabolism
0.698 0.302 0.000
E76 Disorders of glycosaminoglycan metabolism
0.698 0.302 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.698 0.302 0.000
E74 Other disorders of carbohydrate metabolism
0.698 0.302 0.000
E73 Lactose intolerance
0.698 0.302 0.000
E72 Other disorders of amino-acid metabolism
0.698 0.302 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.698 0.302 0.000
E70 Disorders of aromatic amino-acid metabolism
0.698 0.302 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.698 0.302 0.000
I61 Intracerebral haemorrhage
0.698 0.302 0.000
W20-W49 Exposure to inanimate mechanical forces
0.697 0.303 0.000
I10-I15 Hypertensive diseases
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.303 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.697 0.303 0.000
Y57 Other and unspecified drugs and medicaments
0.697 0.303 0.000
M45 Ankylosing spondylitis
0.697 0.303 0.000
I34.1 Mitral (valve) prolapse
0.696 0.303 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
E87.7 Fluid overload
0.695 0.305 0.000
T42.4 Benzodiazepines
0.695 0.305 0.000
F38 Other mood [affective] disorders
0.695 0.305 0.000
F34 Persistent mood [affective] disorders
0.695 0.305 0.000
F30 Manic episode
0.695 0.305 0.000
F39 Unspecified mood [affective] disorder
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.694 0.306 0.000
I25.3 Aneurysm of heart
0.694 0.306 0.000
E34 Other endocrine disorders
0.694 0.306 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.694 0.306 0.000
M06.8 Other specified rheumatoid arthritis
0.693 0.306 0.000
M06.2 Rheumatoid bursitis
0.693 0.306 0.000
M06.1 Adult-onset Still's disease
0.693 0.306 0.000
A41.8 Other specified septicaemia
0.693 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.308 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.308 0.000
T78 Adverse effects, not elsewhere classified
0.692 0.308 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.691 0.309 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.691 0.309 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.691 0.309 0.000
F60.9 Personality disorder, unspecified
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
M81 Osteoporosis without pathological fracture
0.689 0.311 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.311 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.689 0.311 0.000
M54.56 Low back pain (Lumbar region)
0.689 0.311 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.688 0.312 0.000
I89.0 Lymphoedema, not elsewhere classified
0.687 0.313 0.000
I95.8 Other hypotension
0.687 0.313 0.000
I95.0 Idiopathic hypotension
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.687 0.313 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.686 0.314 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.686 0.314 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.686 0.314 0.000
B50-B64 Protozoal diseases
0.686 0.314 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.686 0.314 0.000
A80-A89 Viral infections of the central nervous system
0.686 0.314 0.000
A75-A79 Rickettsioses
0.686 0.314 0.000
A70-A74 Other diseases caused by chlamydiae
0.686 0.314 0.000
A65-A69 Other spirochaetal diseases
0.686 0.314 0.000
A20-A28 Certain zoonotic bacterial diseases
0.686 0.314 0.000
A15-A19 Tuberculosis
0.686 0.314 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.685 0.315 0.000
A49.0 Staphylococcal infection, unspecified
0.685 0.315 0.000
F48 Other neurotic disorders
0.684 0.315 0.000
F44 Dissociative [conversion] disorders
0.684 0.315 0.000
F42 Obsessive-compulsive disorder
0.684 0.315 0.000
I99 Other and unspecified disorders of circulatory system
0.684 0.315 0.000
Y44 Agents primarily affecting blood constituents
0.684 0.316 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.684 0.316 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.683 0.317 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.683 0.317 0.000
C31 Malignant neoplasm of accessory sinuses
0.683 0.317 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.683 0.317 0.000
C37 Malignant neoplasm of thymus
0.683 0.317 0.000
C33 Malignant neoplasm of trachea
0.683 0.317 0.000
I67 Other cerebrovascular diseases
0.683 0.317 0.000
M79.6 Pain in limb
0.682 0.318 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.682 0.318 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.682 0.318 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.682 0.318 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.682 0.318 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.682 0.318 0.000
H04 Disorders of lachrymal system
0.682 0.318 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.682 0.318 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.682 0.318 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.681 0.319 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.680 0.319 0.000
S43.0 Dislocation of shoulder joint
0.680 0.320 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.680 0.320 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.679 0.321 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.679 0.321 0.000
E24 Cushing's syndrome
0.679 0.321 0.000
M79.7 Fibromyalgia
0.679 0.321 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.678 0.322 0.000
M71 Other bursopathies
0.678 0.322 0.000
E78.2 Mixed hyperlipidaemia
0.677 0.323 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.677 0.323 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.677 0.323 0.000
C79.6 Secondary malignant neoplasm of ovary
0.676 0.323 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.676 0.323 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.676 0.323 0.000
K52 Other non-infective gastro-enteritis and colitis
0.676 0.324 0.000
I25.5 Ischaemic cardiomyopathy
0.676 0.324 0.000
M47.8 Other spondylosis
0.675 0.325 0.000
M48.9 Spondylopathy, unspecified
0.675 0.325 0.000
M48.8 Other specified spondylopathies
0.675 0.325 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.675 0.325 0.000
M48.4 Fatigue fracture of vertebra
0.675 0.325 0.000
M48.3 Traumatic spondylopathy
0.675 0.325 0.000
M48.2 Kissing spine
0.675 0.325 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.675 0.325 0.000
C34.8 Overlapping lesion of bronchus and lung
0.675 0.325 0.000
S42 Fracture of shoulder and upper arm
0.674 0.326 0.000
M47.2 Other spondylosis with radiculopathy
0.673 0.327 0.000
K36 Other appendicitis
0.673 0.327 0.000
I45 Other conduction disorders
0.672 0.328 0.000
E00-E07 Disorders of thyroid gland
0.670 0.330 0.000
G96 Other disorders of central nervous system
0.669 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.669 0.331 0.000
F32.9 Depressive episode, unspecified
0.668 0.332 0.000
C77.0 Lymph nodes of head, face and neck
0.668 0.332 0.000
S40 Superficial injury of shoulder and upper arm
0.666 0.334 0.000
Z86 Personal history of certain other diseases
0.666 0.334 0.000
T40.2 Other opioids
0.664 0.335 0.000
A00-A09 Intestinal infectious diseases
0.664 0.336 0.000
K01 Embedded and impacted teeth
0.664 0.336 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.664 0.336 0.000
E32 Diseases of thymus
0.664 0.336 0.000
E31 Polyglandular dysfunction
0.664 0.336 0.000
E30 Disorders of puberty, not elsewhere classified
0.664 0.336 0.000
E26 Hyperaldosteronism
0.664 0.336 0.000
E25 Adrenogenital disorders
0.664 0.336 0.000
E20 Hypoparathyroidism
0.664 0.336 0.000
M79.0 Rheumatism, unspecified
0.664 0.336 0.000
T45.0 Antiallergic and antiemetic drugs
0.663 0.337 0.000
D86 Sarcoidosis
0.663 0.337 0.000
A48 Other bacterial diseases, not elsewhere classified
0.663 0.337 0.000
A44 Bartonellosis
0.663 0.337 0.000
A43 Nocardiosis
0.663 0.337 0.000
A42 Actinomycosis
0.663 0.337 0.000
A39 Meningococcal infection
0.663 0.337 0.000
A37 Whooping cough
0.663 0.337 0.000
A36 Diphtheria
0.663 0.337 0.000
A32 Listeriosis
0.663 0.337 0.000
A31 Infection due to other mycobacteria
0.663 0.337 0.000
A30 Leprosy [Hansen's disease]
0.663 0.337 0.000
A38 Scarlet fever
0.663 0.337 0.000
A35 Other tetanus
0.663 0.337 0.000
A34 Obstetrical tetanus
0.663 0.337 0.000
A33 Tetanus neonatorum
0.663 0.337 0.000
I51.0 Cardiac septal defect, acquired
0.662 0.338 0.000
M77 Other enthesopathies
0.662 0.338 0.000
S30.0 Contusion of lower back and pelvis
0.662 0.338 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.662 0.338 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.662 0.338 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
I51.6 Cardiovascular disease, unspecified
0.660 0.340 0.000
G70-G73 Diseases of myoneural junction and muscle
0.660 0.340 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.659 0.340 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.659 0.340 0.000
M48.04 Spinal stenosis (Thoracic region)
0.659 0.340 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.659 0.340 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.659 0.340 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.659 0.340 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.660 0.340 0.000
C64-C68 Malignant neoplasms of urinary tract
0.659 0.341 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.659 0.341 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.341 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.659 0.341 0.000
K04.3 Abnormal hard tissue formation in pulp
0.659 0.341 0.000
K04.2 Pulp degeneration
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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