TreeWAS – Variant ID: rs72718577

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
H35 Other retinal disorders	0.997	0.003
H35.8 Other specified retinal disorders	0.995	0.005
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.994	0.006
F30-F39 Mood [affective] disorders	0.991	0.009
E00-E07 Disorders of thyroid gland	0.990	0.010
F32 Depressive episode	0.988	0.012
F32.9 Depressive episode, unspecified	0.986	0.014
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.982	0.018
T20-T25 Burns and corrosions of external body surface, specified by site	0.981	0.019
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.981	0.019
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.980	0.020
E03 Other hypothyroidism	0.980	0.020
Chapter XX External causes of morbidity and mortality	0.976	0.024
E03.9 Hypothyroidism, unspecified	0.974	0.026
S20-S29 Injuries to the thorax	0.969	0.031
S32 Fracture of lumbar spine and pelvis	0.958	0.042
E20-E35 Disorders of other endocrine glands	0.951	0.049
H34 Retinal vascular occlusions	0.950	0.050
F00-F09 Organic, including symptomatic, mental disorders	0.950	0.050
H31 Other disorders of choroid	0.945	0.055
S22 Fracture of rib(s), sternum and thoracic spine	0.945	0.055
F60-F69 Disorders of adult personality and behaviour	0.937	0.063
F05 Delirium, not induced by alcohol and other psychoactive substances	0.927	0.073
W00-W19 Falls	0.927	0.073
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.924	0.076
T83.0 Mechanical complication of urinary (indwelling) catheter	0.922	0.078
H36 Retinal disorders in diseases classified elsewhere	0.918	0.082
H34.8 Other retinal vascular occlusions	0.913	0.087
Chapter XII Diseases of the skin and subcutaneous tissue	0.912	0.088
F05.9 Delirium, unspecified	0.912	0.088
S70-S79 Injuries to the hip and thigh	0.904	0.096
S32.5 Fracture of pubis	0.898	0.102
H18 Other disorders of cornea	0.898	0.102
H20 Iridocyclitis	0.894	0.106
E10-E14 Diabetes mellitus	0.893	0.107
F60 Specific personality disorders	0.892	0.108
M20-M25 Other joint disorders	0.891	0.109
S50-S59 Injuries to the elbow and forearm	0.887	0.113
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.884	0.116
S22.3 Fracture of rib	0.884	0.116
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.883	0.117
T20 Burn and corrosion of head and neck	0.882	0.118
E40-E46 Malnutrition	0.881	0.119
E10 Insulin-dependent diabetes mellitus	0.880	0.120
T83.1 Mechanical complication of other urinary devices and implants	0.879	0.121
M80-M85 Disorders of bone density and structure	0.879	0.121
S00-S09 Injuries to the head	0.878	0.122
Chapter VI Diseases of the nervous system	0.877	0.123
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.873	0.127
M35 Other systemic involvement of connective tissue	0.871	0.129
E05 Thyrotoxicosis [hyperthyroidism]	0.868	0.132
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.868	0.132
M35.3 Polymyalgia rheumatica	0.865	0.135
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.863	0.137
M31 Other necrotising vasculopathies	0.860	0.140
H36.0 Diabetic retinopathy	0.860	0.140
S32.50 Fracture of pubis (closed)	0.856	0.144
H31.0 Chorioretinal scars	0.854	0.146
S02 Fracture of skull and facial bones	0.848	0.152
E10.9 Without complications	0.847	0.153
E27 Other disorders of adrenal gland	0.846	0.154
T87 Complications peculiar to reattachment and amputation	0.843	0.157
M31.6 Other giant cell arteritis	0.841	0.159
S22.30 Fracture of rib (closed)	0.839	0.161
W19 Unspecified fall	0.838	0.162
S40-S49 Injuries to the shoulder and upper arm	0.836	0.164
H46-H48 Disorders of optic nerve and visual pathways	0.832	0.168
S32.1 Fracture of sacrum	0.830	0.170
M81 Osteoporosis without pathological fracture	0.824	0.176
H21 Other disorders of iris and ciliary body	0.824	0.176
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.822	0.178
S22.4 Multiple fractures of ribs	0.812	0.187
E10.3 With ophthalmic complications	0.812	0.188
T85 Complications of other internal prosthetic devices, implants and grafts	0.810	0.190
X60-X84 Intentional self-harm	0.810	0.190
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.807	0.193
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.804	0.196
H18.6 Keratoconus	0.804	0.196
H35.0 Background retinopathy and retinal vascular changes	0.803	0.197
S90-S99 Injuries to the ankle and foot	0.802	0.198
E05.9 Thyrotoxicosis, unspecified	0.801	0.199
S22.1 Multiple fractures of thoracic spine	0.801	0.199
T20.2 Burn of second degree of head and neck	0.801	0.199
M86-M90 Other osteopathies	0.800	0.200
E29 Testicular dysfunction	0.800	0.200
W06 Fall involving bed	0.798	0.202
D50-D53 Nutritional anaemias	0.796	0.204
E46 Unspecified protein-energy malnutrition	0.796	0.204
H35.6 Retinal haemorrhage	0.795	0.205
S09 Other and unspecified injuries of head	0.794	0.206
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.794	0.206
S31 Open wound of abdomen, lower back and pelvis	0.792	0.208
E28 Ovarian dysfunction	0.791	0.209
L00-L08 Infections of the skin and subcutaneous tissue	0.789	0.211
T21 Burn and corrosion of trunk	0.787	0.213
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.786	0.214
E50-E64 Other nutritional deficiencies	0.785	0.215
M24 Other specific joint derangements	0.785	0.215
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.784	0.216
S20 Superficial injury of thorax	0.784	0.216
T80 Complications following infusion, transfusion and therapeutic injection	0.779	0.221
S10-S19 Injuries to the neck	0.776	0.224
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.775	0.225
F60.8 Other specific personality disorders	0.773	0.227
X40-X49 Accidental poisoning by and exposure to noxious substances	0.772	0.228
E06 Thyroiditis	0.772	0.228
E23 Hypofunction and other disorders of pituitary gland	0.772	0.228
Y51 Drugs primarily affecting the autonomic nervous system	0.772	0.228
M81.9 Osteoporosis, unspecified	0.772	0.228
H31.1 Choroidal degeneration	0.771	0.229
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.771	0.229
S72 Fracture of femur	0.771	0.229
M65-M68 Disorders of synovium and tendon	0.770	0.230
H31.8 Other specified disorders of choroid	0.770	0.230
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.770	0.230
F99-F99 Unspecified mental disorder	0.769	0.231
T23 Burn and corrosion of wrist and hand	0.769	0.231
L80-L99 Other disorders of the skin and subcutaneous tissue	0.766	0.234
F60.3 Emotionally unstable personality disorder	0.765	0.235
W19.2 School, other institution and public administrative area	0.765	0.235
F34 Persistent mood [affective] disorders	0.763	0.237
L50-L54 Urticaria and erythema	0.763	0.237
V01-V09 Pedestrian injured in transport accident	0.762	0.238
F17 Mental and behavioural disorders due to use of tobacco	0.762	0.238
T86 Failure and rejection of transplanted organs and tissues	0.761	0.239
S79 Other and unspecified injuries of hip and thigh	0.761	0.239
W18 Other fall on same level	0.761	0.239
L20-L30 Dermatitis and eczema	0.760	0.240
H16 Keratitis	0.757	0.243
S51 Open wound of forearm	0.756	0.244
H20.9 Iridocyclitis, unspecified	0.756	0.244
F60.9 Personality disorder, unspecified	0.755	0.245
F01 Vascular dementia	0.755	0.245
F32.3 Severe depressive episode with psychotic symptoms	0.753	0.247
M00-M03 Infectious arthropathies	0.751	0.248
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.749	0.251
F02 Dementia in other diseases classified elsewhere	0.749	0.251
T15-T19 Effects of foreign body entering through natural orifice	0.748	0.252
S32.3 Fracture of ilium	0.748	0.252
Y57 Other and unspecified drugs and medicaments	0.748	0.252
D51 Vitamin B12 deficiency anaemia	0.745	0.255
G50-G59 Nerve, nerve root and plexus disorders	0.741	0.259
W05 Fall involving wheelchair	0.740	0.260
E27.1 Primary adrenocortical insufficiency	0.740	0.260
M81.99 Osteoporosis, unspecified (Site unspecified)	0.739	0.261
H20.0 Acute and subacute iridocyclitis	0.738	0.262
S32.10 Fracture of sacrum (closed)	0.738	0.262
F30 Manic episode	0.737	0.263
S32.4 Fracture of acetabulum	0.737	0.263
F52 Sexual dysfunction, not caused by organic disorder or disease	0.735	0.265
S56 Injury of muscle and tendon at forearm level	0.735	0.265
H18.5 Hereditary corneal dystrophies	0.735	0.265
T88 Other complications of surgical and medical care, not elsewhere classified	0.734	0.265
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.734	0.266
M84 Disorders of continuity of bone	0.734	0.266
X50-X57 Overexertion, travel and privation	0.729	0.271
S80-S89 Injuries to the knee and lower leg	0.727	0.273
F32.0 Mild depressive episode	0.727	0.273
E10.5 With peripheral circulatory complications	0.727	0.273
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.726	0.274
H18.9 Disorder of cornea, unspecified	0.725	0.275
S02.1 Fracture of base of skull	0.724	0.276
E20 Hypoparathyroidism	0.724	0.276
G00-G09 Inflammatory diseases of the central nervous system	0.723	0.276
T83.3 Mechanical complication of intra-uterine contraceptive device	0.723	0.277
H35.4 Peripheral retinal degeneration	0.721	0.279
D70-D77 Other diseases of blood and blood-forming organs	0.720	0.280
Chapter XXII Codes for special purposes	0.720	0.280
S46 Injury of muscle and tendon at shoulder and upper arm level	0.719	0.281
F12 Mental and behavioural disorders due to use of cannabinoids	0.718	0.282
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.717	0.282
S22.40 Multiple fractures of ribs (closed)	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283
H30 Chorioretinal inflammation	0.717	0.283
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.715	0.285
H35.2 Other proliferative retinopathy	0.715	0.285
H35.1 Retinopathy of prematurity	0.715	0.285
S02.4 Fracture of malar and maxillary bones	0.713	0.287
S09.9 Unspecified injury of head	0.712	0.288
V40-V49 Car occupant injured in transport accident	0.712	0.288
Y60-Y69 Misadventures to patients during surgical and medical care	0.712	0.288
F38 Other mood [affective] disorders	0.710	0.289
F39 Unspecified mood [affective] disorder	0.710	0.289
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.710	0.290
E00 Congenital iodine-deficiency syndrome	0.710	0.290
E02 Subclinical iodine-deficiency hypothyroidism	0.710	0.290
T00-T07 Injuries involving multiple body regions	0.710	0.290
F32.8 Other depressive episodes	0.708	0.292
S32.7 Multiple fractures of lumbar spine and pelvis	0.708	0.292
H35.3 Degeneration of macula and posterior pole	0.707	0.293
W19.3 Sports and athletics area	0.706	0.294
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.706	0.294
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.706	0.294
L02 Cutaneous abscess, furuncle and carbuncle	0.706	0.294
S60-S69 Injuries to the wrist and hand	0.705	0.295
W06.0 Home	0.705	0.295
H20.1 Chronic iridocyclitis	0.705	0.295
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.704	0.296
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.704	0.296
H15 Disorders of sclera	0.704	0.296
T25 Burn and corrosion of ankle and foot	0.704	0.296
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.703	0.297
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.703	0.297
T83.2 Mechanical complication of graft of urinary organ	0.703	0.297
X58-X59 Accidental exposure to other and unspecified factors	0.702	0.297
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.702	0.297
S37 Injury of urinary and pelvic organs	0.702	0.297
S36 Injury of intra-abdominal organs	0.702	0.297
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.702	0.297
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.702	0.297
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.702	0.297
E03.5 Myxoedema coma	0.702	0.298
E03.4 Atrophy of thyroid (acquired)	0.702	0.298
E03.3 Postinfectious hypothyroidism	0.702	0.298
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.702	0.298
E03.1 Congenital hypothyroidism without goitre	0.702	0.298
E03.0 Congenital hypothyroidism with diffuse goitre	0.702	0.298
V20-V29 Motorcycle rider injured in transport accident	0.702	0.298
Y00-Y09 Assault	0.702	0.298
S20.2 Contusion of thorax	0.702	0.298
L08 Other local infections of skin and subcutaneous tissue	0.702	0.298
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.701	0.298
E26 Hyperaldosteronism	0.700	0.300
Y35-Y36 Legal intervention and operations of war	0.700	0.300
Y10-Y34 Event of undetermined intent	0.700	0.300
X85-X99 Assault	0.700	0.300
X30-X39 Exposure to forces of nature	0.700	0.300
X10-X19 Contact with heat and hot substances	0.700	0.300
X00-X09 Exposure to smoke, fire and flames	0.700	0.300
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300
W75-W84 Other accidental threats to breathing	0.700	0.300
W65-W74 Accidental drowning and submersion	0.700	0.300
V98-V99 Other and unspecified transport accidents	0.700	0.300
V95-V97 Air and space transport accidents	0.700	0.300
V90-V94 Water transport accidents	0.700	0.300
V70-V79 Bus occupant injured in transport accident	0.700	0.300
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300
H18.2 Other corneal oedema	0.699	0.301
G80-G83 Cerebral palsy and other paralytic syndromes	0.699	0.301
H17 Corneal scars and opacities	0.698	0.302
S22.10 Multiple fractures of thoracic spine (closed)	0.697	0.302
S32.0 Fracture of lumbar vertebra	0.697	0.303
V10-V19 Pedal cyclist injured in transport accident	0.696	0.304
S91 Open wound of ankle and foot	0.695	0.305
F17.1 Harmful use	0.695	0.305
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.695	0.305
S26 Injury of heart	0.695	0.305
S25 Injury of blood vessels of thorax	0.695	0.305
S24 Injury of nerves and spinal cord at thorax level	0.695	0.305
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.695	0.305
S21 Open wound of thorax	0.695	0.305
H35.9 Retinal disorder, unspecified	0.694	0.306
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.694	0.306
T87.3 Neuroma of amputation stump	0.693	0.307
T87.6 Other and unspecified complications of amputation stump	0.693	0.307
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.693	0.307
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.692	0.308
E29.1 Testicular hypofunction	0.691	0.309
H34.2 Other retinal artery occlusions	0.691	0.309
W50-W64 Exposure to animate mechanical forces	0.691	0.309
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.691	0.309
S22.5 Flail chest	0.690	0.309
Y48 Anaesthetics and therapeutic gases	0.690	0.310
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.689	0.310
H43-H45 Disorders of vitreous body and globe	0.689	0.311
F11 Mental and behavioural disorders due to use of opioids	0.689	0.311
T95 Sequelae of burns, corrosions and frostbite	0.689	0.311
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.688	0.312
M32 Systemic lupus erythematosus	0.688	0.312
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.687	0.313
S32.2 Fracture of coccyx	0.687	0.313
S02.3 Fracture of orbital floor	0.686	0.313
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.686	0.314
Y47 Sedatives, hypnotics and antianxiety drugs	0.686	0.314
M24.2 Disorder of ligament	0.686	0.314
W15 Fall from cliff	0.686	0.314
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.685	0.314
S70 Superficial injury of hip and thigh	0.684	0.316
V80-V89 Other land transport accidents	0.683	0.317
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.683	0.317
L84 Corns and callosities	0.683	0.317
T92 Sequelae of injuries of upper limb	0.683	0.317
E24 Cushing's syndrome	0.682	0.318
E35 Disorders of endocrine glands in diseases classified elsewhere	0.681	0.318
E32 Diseases of thymus	0.681	0.318
E31 Polyglandular dysfunction	0.681	0.318
E30 Disorders of puberty, not elsewhere classified	0.681	0.318
E25 Adrenogenital disorders	0.681	0.318
X20-X29 Contact with venomous animals and plants	0.681	0.319
H34.9 Retinal vascular occlusion, unspecified	0.681	0.319
H34.1 Central retinal artery occlusion	0.681	0.319
H34.0 Transient retinal artery occlusion	0.681	0.319
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.681	0.319
F09 Unspecified organic or symptomatic mental disorder	0.681	0.319
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.681	0.319
H46 Optic neuritis	0.680	0.320
S05 Injury of eye and orbit	0.679	0.321
S22.2 Fracture of sternum	0.678	0.322
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.678	0.322
F32.1 Moderate depressive episode	0.678	0.322
H31.9 Disorder of choroid, unspecified	0.678	0.322
H31.4 Choroidal detachment	0.678	0.322
H31.3 Choroidal haemorrhage and rupture	0.678	0.322
H31.2 Hereditary choroidal dystrophy	0.678	0.322
S22.9 Fracture of bony thorax, part unspecified	0.678	0.322
S22.8 Fracture of other parts of bony thorax	0.678	0.322
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.677	0.323
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.677	0.323
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.677	0.323
L29 Pruritus	0.676	0.324
F50 Eating disorders	0.675	0.325
E27.9 Disorder of adrenal gland, unspecified	0.675	0.325
F80-F89 Disorders of psychological development	0.675	0.325
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.674	0.325
L97 Ulcer of lower limb, not elsewhere classified	0.673	0.327
W03 Other fall on same level due to collision with, or pushing by, another person	0.673	0.327
F68 Other disorders of adult personality and behaviour	0.672	0.328
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.672	0.328
F65 Disorders of sexual preference	0.672	0.328
F64 Gender identity disorders	0.672	0.328
F63 Habit and impulse disorders	0.672	0.328
F62 Enduring personality changes, not attributable to brain damage and disease	0.672	0.328
F69 Unspecified disorder of adult personality and behaviour	0.672	0.328
F61 Mixed and other personality disorders	0.672	0.328
E07 Other disorders of thyroid	0.671	0.329
M86 Osteomyelitis	0.670	0.330
W08 Fall involving other furniture	0.670	0.330
S29 Other and unspecified injuries of thorax	0.670	0.330
S02.5 Fracture of tooth	0.669	0.331
Y41 Other systemic anti-infectives and antiparasitics	0.668	0.332
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.667	0.333
W20-W49 Exposure to inanimate mechanical forces	0.665	0.335
F05.8 Other delirium	0.665	0.335
F05.1 Delirium superimposed on dementia	0.665	0.335
F05.0 Delirium not superimposed on dementia, so described	0.665	0.335
M40-M43 Deforming dorsopathies	0.665	0.335
W16 Diving or jumping into water causing injury other than drowning or submersion	0.664	0.335
W14 Fall from tree	0.664	0.335
W12 Fall on and from scaffolding	0.664	0.335
W11 Fall on and from ladder	0.664	0.335
W09 Fall involving playground equipment	0.664	0.335
W04 Fall while being carried or supported by other persons	0.664	0.335
W01 Fall on same level from slipping, tripping and stumbling	0.664	0.335
W00 Fall on same level involving ice and snow	0.664	0.335
G90-G99 Other disorders of the nervous system	0.664	0.336
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.664	0.336
S50 Superficial injury of forearm	0.664	0.336
E27.8 Other specified disorders of adrenal gland	0.662	0.337
E23.2 Diabetes insipidus	0.662	0.338
T20.1 Burn of first degree of head and neck	0.662	0.338
T91 Sequelae of injuries of neck and trunk	0.662	0.338
H21.1 Other vascular disorders of iris and ciliary body	0.662	0.338
L50 Urticaria	0.660	0.340
S79.9 Unspecified injury of hip and thigh	0.658	0.342
H36.8 Other retinal disorders in diseases classified elsewhere	0.658	0.342
M81.0 Postmenopausal osteoporosis	0.657	0.342
D70 Agranulocytosis	0.655	0.345
S22.0 Fracture of thoracic vertebra	0.655	0.345
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.654	0.345
T85.4 Mechanical complication of breast prosthesis and implant	0.654	0.346
S30 Superficial injury of abdomen, lower back and pelvis	0.654	0.346
L10-L14 Bullous disorders	0.654	0.346
M67 Other disorders of synovium and tendon	0.654	0.346
M21 Other acquired deformities of limbs	0.652	0.347
W19.4 Street and highway	0.652	0.348
D52 Folate deficiency anaemia	0.652	0.348
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.652	0.348
E28.2 Polycystic ovarian syndrome	0.651	0.348
S02.6 Fracture of mandible	0.651	0.349
Y49 Psychotropic drugs, not elsewhere classified	0.650	0.350
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.650	0.350
H21.5 Other adhesions and disruptions of iris and ciliary body	0.648	0.352
S78 Traumatic amputation of hip and thigh	0.648	0.352
S77 Crushing injury of hip and thigh	0.648	0.352
S76 Injury of muscle and tendon at hip and thigh level	0.648	0.352
S75 Injury of blood vessels at hip and thigh level	0.648	0.352
S74 Injury of nerves at hip and thigh level	0.648	0.352
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.648	0.352
E10.2 With renal complications	0.648	0.352
T84.3 Mechanical complication of other bone devices, implants and grafts	0.648	0.352
E27.2 Addisonian crisis	0.647	0.353
T21.2 Burn of second degree of trunk	0.647	0.353
H47 Other disorders of optic [2nd] nerve and visual pathways	0.646	0.354
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.646	0.354
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.645	0.355
S31.1 Open wound of abdominal wall	0.645	0.355
S49 Other and unspecified injuries of shoulder and upper arm	0.645	0.355
S32.51 Fracture of pubis (open)	0.644	0.356
G20-G26 Extrapyramidal and movement disorders	0.644	0.356
H18.7 Other corneal deformities	0.644	0.356
H18.3 Changes in corneal membranes	0.644	0.356
H18.1 Bullous keratopathy	0.644	0.356
H18.0 Corneal pigmentations and deposits	0.644	0.356
F52.2 Failure of genital response	0.643	0.357
E65-E68 Obesity and other hyperalimentation	0.641	0.359
H20.8 Other iridocyclitis	0.641	0.359
H20.2 Lens-induced iridocyclitis	0.641	0.359
E12 Malnutrition-related diabetes mellitus	0.640	0.359
M91-M94 Chondropathies	0.640	0.360
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.640	0.360
M85 Other disorders of bone density and structure	0.640	0.360
S09.0 Injury of blood vessels of head, not elsewhere classified	0.640	0.360
S99 Other and unspecified injuries of ankle and foot	0.639	0.360
F60.7 Dependent personality disorder	0.639	0.360
F60.6 Anxious [avoidant] personality disorder	0.639	0.360
F60.5 Anankastic personality disorder	0.639	0.360
F60.4 Histrionic personality disorder	0.639	0.360
F60.2 Dissocial personality disorder	0.639	0.360
F60.1 Schizoid personality disorder	0.639	0.360
F60.0 Paranoid personality disorder	0.639	0.360
E55 Vitamin D deficiency	0.639	0.361
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.639	0.361
M33 Dermatopolymyositis	0.639	0.361
S72.3 Fracture of shaft of femur	0.638	0.362
S02.9 Fracture of skull and facial bones, part unspecified	0.637	0.363
S51.9 Open wound of forearm, part unspecified	0.636	0.364
X78 Intentional self-harm by sharp object	0.636	0.364
S59 Other and unspecified injuries of forearm	0.636	0.364
S58 Traumatic amputation of forearm	0.636	0.364
S57 Crushing injury of forearm	0.636	0.364
S55 Injury of blood vessels at forearm level	0.636	0.364
S54 Injury of nerves at forearm level	0.636	0.364
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.636	0.364
M82 Osteoporosis in diseases classified elsewhere	0.636	0.364
M30 Polyarteritis nodosa and related conditions	0.636	0.364
S02.10 Fracture of base of skull (closed)	0.635	0.365
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.635	0.365
G40-G47 Episodic and paroxysmal disorders	0.635	0.365
F00 Dementia in Alzheimer's disease	0.634	0.366
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.634	0.366
F18 Mental and behavioural disorders due to use of volatile solvents	0.634	0.366
F16 Mental and behavioural disorders due to use of hallucinogens	0.634	0.366
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.634	0.366
F14 Mental and behavioural disorders due to use of cocaine	0.634	0.366
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.634	0.366
S22.31 Fracture of rib (open)	0.633	0.366
W07 Fall involving chair	0.633	0.367
D55-D59 Haemolytic anaemias	0.633	0.367
Y59 Other and unspecified vaccines and biological substances	0.633	0.367
Y58 Bacterial vaccines	0.633	0.367
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.633	0.367
Y53 Agents primarily affecting the gastro-intestinal system	0.633	0.367
Y50 Central nervous system stimulants, not elsewhere classified	0.633	0.367
Y46 Antiepileptics and anti-Parkinsonism drugs	0.633	0.367
T20.7 Corrosion of third degree of head and neck	0.632	0.368
T20.6 Corrosion of second degree of head and neck	0.632	0.368
T20.5 Corrosion of first degree of head and neck	0.632	0.368
T20.4 Corrosion of unspecified degree of head and neck	0.632	0.368
T20.3 Burn of third degree of head and neck	0.632	0.368
T20.0 Burn of unspecified degree of head and neck	0.632	0.368
S02.8 Fractures of other skull and facial bones	0.632	0.368
H10-H13 Disorders of conjunctiva	0.632	0.368
L29.9 Pruritus, unspecified	0.632	0.368
E44 Protein-energy malnutrition of moderate and mild degree	0.631	0.369
E45 Retarded development following protein-energy malnutrition	0.631	0.369
E43 Unspecified severe protein-energy malnutrition	0.631	0.369
E42 Marasmic kwashiorkor	0.631	0.369
E41 Nutritional marasmus	0.631	0.369
E40 Kwashiorkor	0.631	0.369
E10.8 With unspecified complications	0.631	0.369
E10.7 With multiple complications	0.631	0.369
E10.6 With other specified complications	0.631	0.369
E10.0 With coma	0.631	0.369
M60-M63 Disorders of muscles	0.631	0.369
M83 Adult osteomalacia	0.630	0.370
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.630	0.370
M05-M14 Inflammatory polyarthropathies	0.630	0.370
S08 Traumatic amputation of part of head	0.629	0.371
S07 Crushing injury of head	0.629	0.371
S04 Injury of cranial nerves	0.629	0.371
S03 Dislocation, sprain and strain of joints and ligaments of head	0.629	0.371
S71 Open wound of hip and thigh	0.629	0.371
Y40 Systemic antibiotics	0.628	0.372
E10.4 With neurological complications	0.628	0.372
M00 Pyogenic arthritis	0.628	0.372
S27 Injury of other and unspecified intrathoracic organs	0.627	0.373
S02.7 Multiple fractures involving skull and facial bones	0.627	0.373
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.626	0.374
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.626	0.374
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.626	0.374
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.626	0.374
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.626	0.374
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.626	0.374
L80 Vitiligo	0.625	0.374
M35.9 Systemic involvement of connective tissue, unspecified	0.624	0.375
M35.8 Other specified systemic involvement of connective tissue	0.624	0.375
M35.6 Relapsing panniculitis [Weber-Christian]	0.624	0.375

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations