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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72720853
log Bayes Factor = 18.1353
Chromosome 14   position 62,630,726  (GRCh37) Explore rs72720853 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
I50 Heart failure
0.993 0.007 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.991 0.009 0.000
Chapter XI Diseases of the digestive system
0.987 0.013 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.985 0.015 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.016 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.983 0.017 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.981 0.019 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.977 0.023 0.000
N40-N51 Diseases of male genital organs
0.975 0.025 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.975 0.025 0.000
I50.1 Left ventricular failure
0.975 0.025 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.967 0.033 0.000
G40-G47 Episodic and paroxysmal disorders
0.964 0.036 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.963 0.037 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.962 0.038 0.000
I42 Cardiomyopathy
0.962 0.038 0.000
H30-H36 Disorders of choroid and retina
0.958 0.042 0.000
N40 Hyperplasia of prostate
0.951 0.049 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.951 0.049 0.000
E65-E68 Obesity and other hyperalimentation
0.946 0.054 0.000
G20-G26 Extrapyramidal and movement disorders
0.944 0.056 0.000
E10-E14 Diabetes mellitus
0.942 0.058 0.000
R41.0 Disorientation, unspecified
0.942 0.058 0.000
M45-M49 Spondylopathies
0.940 0.060 0.000
Z88.6 Personal history of allergy to analgesic agent
0.939 0.061 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.936 0.064 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.931 0.069 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.929 0.071 0.000
I20 Angina pectoris
0.928 0.072 0.000
M70-M79 Other soft tissue disorders
0.925 0.075 0.000
K90-K93 Other diseases of the digestive system
0.923 0.077 0.000
I25.1 Atherosclerotic heart disease
0.922 0.078 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.915 0.085 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.914 0.086 0.000
E66 Obesity
0.914 0.086 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.914 0.086 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.913 0.087 0.000
Z50 Care involving use of rehabilitation procedures
0.911 0.089 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.910 0.090 0.000
M47 Spondylosis
0.903 0.097 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.902 0.098 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.901 0.099 0.000
R47-R49 Symptoms and signs involving speech and voice
0.901 0.099 0.000
I51 Complications and ill-defined descriptions of heart disease
0.899 0.101 0.000
H33 Retinal detachments and breaks
0.895 0.105 0.000
K14 Diseases of tongue
0.889 0.111 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.888 0.112 0.000
E14 Unspecified diabetes mellitus
0.885 0.115 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.884 0.116 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.880 0.120 0.000
Chapter XX External causes of morbidity and mortality
0.880 0.120 0.000
E66.9 Obesity, unspecified
0.877 0.123 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.872 0.128 0.000
I71 Aortic aneurysm and dissection
0.872 0.128 0.000
Z95.0 Presence of cardiac pacemaker
0.871 0.129 0.000
R42 Dizziness and giddiness
0.866 0.134 0.000
K92 Other diseases of digestive system
0.864 0.136 0.000
Z50.1 Other physical therapy
0.862 0.138 0.000
M47.8 Other spondylosis
0.862 0.138 0.000
I42.0 Dilated cardiomyopathy
0.861 0.139 0.000
Z95.2 Presence of prosthetic heart valve
0.861 0.139 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.860 0.140 0.000
N48 Other disorders of penis
0.857 0.143 0.000
H40-H42 Glaucoma
0.857 0.143 0.000
R07 Pain in throat and chest
0.857 0.143 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.856 0.144 0.000
I50.0 Congestive heart failure
0.856 0.144 0.000
Z98 Other postsurgical states
0.854 0.146 0.000
G20 Parkinson's disease
0.852 0.148 0.000
I20.8 Other forms of angina pectoris
0.850 0.150 0.000
H35 Other retinal disorders
0.846 0.154 0.000
Chapter X Diseases of the respiratory system
0.846 0.154 0.000
R94 Abnormal results of function studies
0.845 0.155 0.000
Z86 Personal history of certain other diseases
0.845 0.155 0.000
I50.9 Heart failure, unspecified
0.845 0.155 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.844 0.156 0.000
G40 Epilepsy
0.839 0.161 0.000
E14.9 Without complications
0.838 0.162 0.000
S60-S69 Injuries to the wrist and hand
0.837 0.162 0.000
N30-N39 Other diseases of urinary system
0.837 0.163 0.000
K08 Other disorders of teeth and supporting structures
0.835 0.165 0.000
H33.2 Serous retinal detachment
0.834 0.166 0.000
K92.1 Melaena
0.833 0.167 0.000
K70-K77 Diseases of liver
0.831 0.169 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.830 0.170 0.000
N25-N29 Other disorders of kidney and ureter
0.828 0.172 0.000
R40 Somnolence, stupor and coma
0.828 0.172 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.827 0.173 0.000
R41.3 Other amnesia
0.826 0.174 0.000
Z13 Special screening examination for other diseases and disorders
0.825 0.175 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.825 0.175 0.000
N43 Hydrocele and spermatocele
0.823 0.177 0.000
K05 Gingivitis and periodontal diseases
0.822 0.178 0.000
N42 Other disorders of prostate
0.821 0.179 0.000
Z45 Adjustment and management of implanted device
0.818 0.182 0.000
Z93 Artificial opening status
0.815 0.185 0.000
R47 Speech disturbances, not elsewhere classified
0.813 0.187 0.000
R07.4 Chest pain, unspecified
0.813 0.187 0.000
M79.6 Pain in limb
0.813 0.187 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.812 0.188 0.000
G81 Hemiplegia
0.810 0.190 0.000
H52 Disorders of refraction and accommodation
0.808 0.192 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.808 0.192 0.000
K02 Dental caries
0.806 0.193 0.000
E20-E35 Disorders of other endocrine glands
0.806 0.194 0.000
M48 Other spondylopathies
0.804 0.196 0.000
M72 Fibroblastic disorders
0.802 0.198 0.000
E11 Non-insulin-dependent diabetes mellitus
0.800 0.200 0.000
K04 Diseases of pulp and periapical tissues
0.799 0.201 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.799 0.201 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.798 0.202 0.000
I31 Other diseases of pericardium
0.798 0.202 0.000
I25.5 Ischaemic cardiomyopathy
0.796 0.204 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.796 0.204 0.000
R25 Abnormal involuntary movements
0.792 0.207 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.793 0.207 0.000
I34 Nonrheumatic mitral valve disorders
0.792 0.208 0.000
M40-M43 Deforming dorsopathies
0.791 0.208 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.789 0.211 0.000
K14.9 Disease of tongue, unspecified
0.785 0.215 0.000
Z47 Other orthopaedic follow-up care
0.785 0.215 0.000
G24 Dystonia
0.781 0.219 0.000
H43-H45 Disorders of vitreous body and globe
0.781 0.219 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.779 0.221 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.779 0.221 0.000
I42.9 Cardiomyopathy, unspecified
0.779 0.221 0.000
I33 Acute and subacute endocarditis
0.778 0.221 0.000
I05-I09 Chronic rheumatic heart diseases
0.778 0.222 0.000
N20-N23 Urolithiasis
0.777 0.223 0.000
K13 Other diseases of lip and oral mucosa
0.777 0.223 0.000
M50-M54 Other dorsopathies
0.775 0.225 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.775 0.225 0.000
R06 Abnormalities of breathing
0.774 0.226 0.000
N99-N99 Other disorders of the genitourinary system
0.773 0.227 0.000
H35.3 Degeneration of macula and posterior pole
0.770 0.230 0.000
I42.2 Other hypertrophic cardiomyopathy
0.769 0.231 0.000
R27 Other lack of coordination
0.769 0.231 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.768 0.232 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.767 0.233 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.766 0.234 0.000
H53-H54 Visual disturbances and blindness
0.764 0.236 0.000
G90-G99 Other disorders of the nervous system
0.762 0.238 0.000
Z88.2 Personal history of allergy to sulphonamides
0.759 0.241 0.000
H10-H13 Disorders of conjunctiva
0.759 0.241 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.759 0.241 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.758 0.242 0.000
G25 Other extrapyramidal and movement disorders
0.758 0.242 0.000
Z50.5 Speech therapy
0.758 0.242 0.000
H04 Disorders of lachrymal system
0.757 0.243 0.000
H40 Glaucoma
0.756 0.244 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.756 0.244 0.000
Z48 Other surgical follow-up care
0.756 0.244 0.000
N36 Other disorders of urethra
0.756 0.244 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.755 0.245 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.755 0.245 0.000
J90-J94 Other diseases of pleura
0.755 0.245 0.000
E66.8 Other obesity
0.754 0.246 0.000
Z90.1 Acquired absence of breast(s)
0.754 0.246 0.000
Chapter II Neoplasms
0.753 0.247 0.000
R26 Abnormalities of gait and mobility
0.749 0.251 0.000
I24 Other acute ischaemic heart diseases
0.748 0.251 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.748 0.252 0.000
G80 Infantile cerebral palsy
0.748 0.252 0.000
I51.8 Other ill-defined heart diseases
0.747 0.253 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.746 0.254 0.000
I22 Subsequent myocardial infarction
0.744 0.256 0.000
N17-N19 Renal failure
0.744 0.256 0.000
H55-H59 Other disorders of eye and adnexa
0.744 0.256 0.000
G47 Sleep disorders
0.741 0.259 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.741 0.259 0.000
Z04 Examination and observation for other reasons
0.741 0.259 0.000
I45 Other conduction disorders
0.739 0.261 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.739 0.261 0.000
I47 Paroxysmal tachycardia
0.739 0.261 0.000
G81.9 Hemiplegia, unspecified
0.738 0.262 0.000
I20.0 Unstable angina
0.738 0.262 0.000
H00 Hordeolum and chalazion
0.737 0.262 0.000
R29.6 Tendency to fall, not elsewhere classified
0.737 0.263 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.737 0.263 0.000
Z95.3 Presence of xenogenic heart valve
0.736 0.264 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.736 0.264 0.000
R94.5 Abnormal results of liver function studies
0.733 0.267 0.000
Z98.8 Other specified postsurgical states
0.732 0.268 0.000
M47.82 Other spondylosis (Cervical region)
0.731 0.269 0.000
I51.7 Cardiomegaly
0.731 0.269 0.000
Z50.0 Cardiac rehabilitation
0.729 0.271 0.000
Z50.2 Alcohol rehabilitation
0.729 0.271 0.000
E00-E07 Disorders of thyroid gland
0.729 0.271 0.000
Chapter V Mental and behavioural disorders
0.727 0.273 0.000
H36 Retinal disorders in diseases classified elsewhere
0.726 0.274 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
K07 Dentofacial anomalies [including malocclusion]
0.723 0.277 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.723 0.277 0.000
G43 Migraine
0.723 0.277 0.000
K50-K52 Noninfective enteritis and colitis
0.723 0.277 0.000
H52.0 Hypermetropia
0.722 0.277 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.721 0.279 0.000
R47.8 Other and unspecified speech disturbances
0.719 0.281 0.000
N48.6 Balanitis xerotica obliterans
0.718 0.282 0.000
I51.9 Heart disease, unspecified
0.717 0.283 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K82 Other diseases of gallbladder
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I37 Pulmonary valve disorders
0.716 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
I30 Acute pericarditis
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.284 0.000
N39 Other disorders of urinary system
0.716 0.284 0.000
R94.3 Abnormal results of cardiovascular function studies
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
K04.7 Periapical abscess without sinus
0.715 0.285 0.000
G44 Other headache syndromes
0.715 0.285 0.000
N50 Other disorders of male genital organs
0.715 0.285 0.000
N43.3 Hydrocele, unspecified
0.714 0.286 0.000
Z41 Procedures for purposes other than remedying health state
0.714 0.286 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.714 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.287 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.712 0.287 0.000
K05.3 Chronic periodontitis
0.712 0.288 0.000
H33.0 Retinal detachment with retinal break
0.712 0.288 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.712 0.288 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
R46 Symptoms and signs involving appearance and behaviour
0.710 0.289 0.000
R45 Symptoms and signs involving emotional state
0.710 0.289 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.710 0.289 0.000
R43 Disturbances of smell and taste
0.710 0.289 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.710 0.290 0.000
S62 Fracture at wrist and hand level
0.709 0.291 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.709 0.291 0.000
M79.66 Pain in limb (Lower leg)
0.708 0.292 0.000
Z43 Attention to artificial openings
0.708 0.292 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.708 0.292 0.000
Z90.3 Acquired absence of part of stomach
0.708 0.292 0.000
M48.0 Spinal stenosis
0.707 0.293 0.000
Z86.7 Personal history of diseases of the circulatory system
0.707 0.293 0.000
N41 Inflammatory diseases of prostate
0.707 0.293 0.000
M47.9 Spondylosis, unspecified
0.706 0.293 0.000
J30-J39 Other diseases of upper respiratory tract
0.706 0.294 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.706 0.294 0.000
M80-M85 Disorders of bone density and structure
0.705 0.295 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.705 0.295 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.705 0.295 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.704 0.296 0.000
S80-S89 Injuries to the knee and lower leg
0.704 0.296 0.000
Z90.0 Acquired absence of part of head and neck
0.703 0.297 0.000
K14.8 Other diseases of tongue
0.703 0.297 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.703 0.297 0.000
Z45.2 Adjustment and management of vascular access device
0.701 0.299 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.699 0.301 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.699 0.301 0.000
N46 Male infertility
0.699 0.301 0.000
N44 Torsion of testis
0.699 0.301 0.000
K10 Other diseases of jaws
0.699 0.301 0.000
K09 Cysts of oral region, not elsewhere classified
0.699 0.301 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.699 0.301 0.000
K03 Other diseases of hard tissues of teeth
0.699 0.301 0.000
K00 Disorders of tooth development and eruption
0.699 0.301 0.000
K11 Diseases of salivary glands
0.698 0.301 0.000
H01 Other inflammation of eyelid
0.697 0.303 0.000
Z83 Family history of other specific disorders
0.697 0.303 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.697 0.303 0.000
Z90.8 Acquired absence of other organs
0.697 0.303 0.000
D10-D36 Benign neoplasms
0.697 0.303 0.000
R49 Voice disturbances
0.696 0.304 0.000
N42.8 Other specified disorders of prostate
0.696 0.304 0.000
N60-N64 Disorders of breast
0.695 0.305 0.000
E11.3 With ophthalmic complications
0.695 0.305 0.000
E50-E64 Other nutritional deficiencies
0.694 0.306 0.000
M91-M94 Chondropathies
0.693 0.307 0.000
M60-M63 Disorders of muscles
0.693 0.307 0.000
M00-M03 Infectious arthropathies
0.693 0.307 0.000
R41.2 Retrograde amnesia
0.693 0.307 0.000
R41.1 Anterograde amnesia
0.693 0.307 0.000
K30 Dyspepsia
0.693 0.307 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.692 0.308 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.691 0.309 0.000
G41 Status epilepticus
0.691 0.309 0.000
M47.2 Other spondylosis with radiculopathy
0.691 0.309 0.000
I25.2 Old myocardial infarction
0.690 0.310 0.000
I42.8 Other cardiomyopathies
0.689 0.310 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.689 0.310 0.000
I42.6 Alcoholic cardiomyopathy
0.689 0.310 0.000
I42.5 Other restrictive cardiomyopathy
0.689 0.310 0.000
I42.4 Endocardial fibroelastosis
0.689 0.310 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.689 0.310 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.689 0.311 0.000
N48.1 Balanoposthitis
0.689 0.311 0.000
H02 Other disorders of eyelid
0.688 0.312 0.000
S67 Crushing injury of wrist and hand
0.688 0.312 0.000
N23 Unspecified renal colic
0.688 0.312 0.000
K14.0 Glossitis
0.688 0.312 0.000
I26 Pulmonary embolism
0.688 0.312 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.687 0.313 0.000
H31 Other disorders of choroid
0.687 0.313 0.000
H30 Chorioretinal inflammation
0.687 0.313 0.000
N45 Orchitis and epididymitis
0.687 0.313 0.000
S61 Open wound of wrist and hand
0.687 0.313 0.000
S40-S49 Injuries to the shoulder and upper arm
0.687 0.313 0.000
K08.3 Retained dental root
0.686 0.314 0.000
H04.2 Epiphora
0.686 0.314 0.000
Z94 Transplanted organ and tissue status
0.686 0.314 0.000
K02.9 Dental caries, unspecified
0.686 0.314 0.000
J00-J06 Acute upper respiratory infections
0.686 0.314 0.000
I35 Nonrheumatic aortic valve disorders
0.685 0.315 0.000
I20.9 Angina pectoris, unspecified
0.685 0.315 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.685 0.315 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.685 0.315 0.000
E11.4 With neurological complications
0.684 0.316 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.680 0.320 0.000
I74 Arterial embolism and thrombosis
0.679 0.321 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.679 0.321 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.679 0.321 0.000
E67 Other hyperalimentation
0.678 0.321 0.000
E68 Sequelae of hyperalimentation
0.678 0.321 0.000
E65 Localised adiposity
0.678 0.321 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.678 0.322 0.000
Z87 Personal history of other diseases and conditions
0.678 0.322 0.000
R07.1 Chest pain on breathing
0.677 0.323 0.000
G23 Other degenerative diseases of basal ganglia
0.677 0.323 0.000
G21 Secondary Parkinsonism
0.677 0.323 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.677 0.323 0.000
G22 Parkinsonism in diseases classified elsewhere
0.677 0.323 0.000
M46 Other inflammatory spondylopathies
0.676 0.324 0.000
E13 Other specified diabetes mellitus
0.676 0.324 0.000
E12 Malnutrition-related diabetes mellitus
0.676 0.324 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.675 0.325 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.674 0.326 0.000
S00-S09 Injuries to the head
0.674 0.326 0.000
I31.9 Disease of pericardium, unspecified
0.674 0.326 0.000
M49 Spondylopathies in diseases classified elsewhere
0.674 0.326 0.000
M77 Other enthesopathies
0.673 0.327 0.000
Z54 Convalescence
0.671 0.329 0.000
Z52 Donors of organs and tissues
0.671 0.329 0.000
Z49 Care involving dialysis
0.671 0.329 0.000
Z44 Fitting and adjustment of external prosthetic device
0.671 0.329 0.000
G30-G32 Other degenerative diseases of the nervous system
0.671 0.329 0.000
G40.9 Epilepsy, unspecified
0.671 0.329 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.670 0.330 0.000
M79.63 Pain in limb (Forearm)
0.670 0.330 0.000
H52.1 Myopia
0.670 0.330 0.000
N36.8 Other specified disorders of urethra
0.669 0.331 0.000
E70-E90 Metabolic disorders
0.669 0.331 0.000
R06.5 Mouth breathing
0.669 0.331 0.000
I38 Endocarditis, valve unspecified
0.668 0.332 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.667 0.333 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.667 0.333 0.000
E14.3 With ophthalmic complications
0.667 0.333 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.666 0.334 0.000
K73 Chronic hepatitis, not elsewhere classified
0.666 0.334 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.666 0.334 0.000
R40.0 Somnolence
0.665 0.335 0.000
I20.1 Angina pectoris with documented spasm
0.665 0.335 0.000
G24.9 Dystonia, unspecified
0.665 0.335 0.000
M75 Shoulder lesions
0.665 0.335 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.664 0.336 0.000
M76 Enthesopathies of lower limb, excluding foot
0.663 0.336 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.663 0.336 0.000
M71 Other bursopathies
0.663 0.336 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.663 0.336 0.000
R47.1 Dysarthria and anarthria
0.663 0.337 0.000
Z97 Presence of other devices
0.663 0.337 0.000
K50 Crohn's disease [regional enteritis]
0.663 0.337 0.000
Y84.8 Other medical procedures
0.662 0.338 0.000
M47.86 Other spondylosis (Lumbar region)
0.662 0.338 0.000
Z40 Prophylactic surgery
0.662 0.338 0.000
K65-K67 Diseases of peritoneum
0.662 0.338 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.662 0.338 0.000
Z90.2 Acquired absence of lung [part of]
0.661 0.339 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.660 0.339 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.660 0.340 0.000
Z50.8 Care involving use of rehabilitation procedures
0.660 0.340 0.000
Chapter VIII Diseases of the ear and mastoid process
0.660 0.340 0.000
M45 Ankylosing spondylitis
0.659 0.341 0.000
R40.2 Coma, unspecified
0.659 0.341 0.000
I34.0 Mitral (valve) insufficiency
0.658 0.341 0.000
S90-S99 Injuries to the ankle and foot
0.658 0.341 0.000
S20-S29 Injuries to the thorax
0.657 0.343 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.656 0.344 0.000
I72 Other aneurysm
0.656 0.344 0.000
I70 Atherosclerosis
0.656 0.344 0.000
K12 Stomatitis and related lesions
0.656 0.344 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.656 0.344 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.655 0.344 0.000
E66.1 Drug-induced obesity
0.655 0.344 0.000
E66.0 Obesity due to excess calories
0.655 0.344 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.655 0.345 0.000
Z10 Routine general health check-up of defined subpopulation
0.655 0.345 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.655 0.345 0.000
H05 Disorders of orbit
0.654 0.345 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.654 0.345 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.654 0.346 0.000
I60-I69 Cerebrovascular diseases
0.654 0.346 0.000
Z50.6 Orthoptic training
0.653 0.347 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.653 0.347 0.000
Z50.3 Drug rehabilitation
0.653 0.347 0.000
K86 Other diseases of pancreas
0.653 0.347 0.000
G83 Other paralytic syndromes
0.652 0.348 0.000
G82 Paraplegia and tetraplegia
0.652 0.348 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.651 0.349 0.000
M54 Dorsalgia
0.651 0.349 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.650 0.349 0.000
R25.2 Cramp and spasm
0.649 0.351 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.649 0.351 0.000
Z93.5 Cystostomy status
0.649 0.351 0.000
I46 Cardiac arrest
0.649 0.351 0.000
H40.9 Glaucoma, unspecified
0.649 0.351 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.648 0.352 0.000
V10-V19 Pedal cyclist injured in transport accident
0.647 0.352 0.000
M47.1 Other spondylosis with myelopathy
0.647 0.352 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.647 0.352 0.000
K25 Gastric ulcer
0.647 0.353 0.000
T79-T79 Certain early complications of trauma
0.647 0.353 0.000
T33-T35 Frostbite
0.647 0.353 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.647 0.353 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.647 0.353 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.647 0.353 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.647 0.353 0.000
T00-T07 Injuries involving multiple body regions
0.647 0.353 0.000
S10-S19 Injuries to the neck
0.647 0.353 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.646 0.354 0.000
M41 Scoliosis
0.646 0.354 0.000
I51.6 Cardiovascular disease, unspecified
0.645 0.355 0.000
I51.5 Myocardial degeneration
0.645 0.355 0.000
I51.4 Myocarditis, unspecified
0.645 0.355 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.645 0.355 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.645 0.355 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.645 0.355 0.000
I51.0 Cardiac septal defect, acquired
0.645 0.355 0.000
H33.5 Other retinal detachments
0.642 0.358 0.000
H33.4 Traction detachment of retina
0.642 0.358 0.000
H33.1 Retinoschisis and retinal cysts
0.642 0.358 0.000
R06.0 Dyspnoea
0.642 0.358 0.000
G35 Multiple sclerosis
0.641 0.359 0.000
J95-J99 Other diseases of the respiratory system
0.641 0.359 0.000
W20-W49 Exposure to inanimate mechanical forces
0.641 0.359 0.000
N48.4 Impotence of organic origin
0.640 0.360 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.640 0.360 0.000
H33.3 Retinal breaks without detachment
0.639 0.361 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.638 0.362 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.638 0.362 0.000
K14.6 Glossodynia
0.638 0.362 0.000
K14.5 Plicated tongue
0.638 0.362 0.000
K14.4 Atrophy of tongue papillae
0.638 0.362 0.000
K14.3 Hypertrophy of tongue papillae
0.638 0.362 0.000
K14.2 Median rhomboid glossitis
0.638 0.362 0.000
K14.1 Geographic tongue
0.638 0.362 0.000
K01 Embedded and impacted teeth
0.637 0.363 0.000
Z99.3 Dependence on wheelchair
0.637 0.363 0.000
R29.4 Clicking hip
0.636 0.363 0.000
R29.3 Abnormal posture
0.636 0.363 0.000
R29.2 Abnormal reflex
0.636 0.363 0.000
R29.1 Meningismus
0.636 0.363 0.000
R29.0 Tetany
0.636 0.363 0.000
Z01.8 Other specified special examinations
0.636 0.364 0.000
K74 Fibrosis and cirrhosis of liver
0.636 0.364 0.000
E10 Insulin-dependent diabetes mellitus
0.635 0.365 0.000
E14.8 With unspecified complications
0.635 0.365 0.000
E14.7 With multiple complications
0.635 0.365 0.000
E14.6 With other specified complications
0.635 0.365 0.000
E14.5 With peripheral circulatory complications
0.635 0.365 0.000
E14.4 With neurological complications
0.635 0.365 0.000
E14.2 Withrenal complications
0.635 0.365 0.000
E14.1 With ketoacidosis
0.635 0.365 0.000
E14.0 With coma
0.635 0.365 0.000
Z12 Special screening examination for neoplasms
0.634 0.366 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.634 0.366 0.000
G45.4 Transient global amnesia
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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