TreeWAS – Variant ID: rs72732571

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
D10-D36 Benign neoplasms	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
Chapter X Diseases of the respiratory system	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
I30-I52 Other forms of heart disease	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.993	0.007
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.991	0.009
D17 Benign lipomatous neoplasm	0.991	0.009
T36-T50 Poisoning by drugs, medicaments and biological substances	0.989	0.011
Chapter VI Diseases of the nervous system	0.987	0.013
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.979	0.021
J40-J47 Chronic lower respiratory diseases	0.972	0.028
R00 Abnormalities of heart beat	0.968	0.032
E10-E14 Diabetes mellitus	0.966	0.034
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.966	0.034
J90-J94 Other diseases of pleura	0.964	0.036
I84 Haemorrhoids	0.962	0.038
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.953	0.047
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.945	0.055
I51 Complications and ill-defined descriptions of heart disease	0.939	0.061
R50-R69 General symptoms and signs	0.937	0.063
G80-G83 Cerebral palsy and other paralytic syndromes	0.936	0.064
Chapter XI Diseases of the digestive system	0.935	0.065
G90-G99 Other disorders of the nervous system	0.935	0.065
C15-C26 Malignant neoplasms of digestive organs	0.935	0.065
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.935	0.065
J44 Other chronic obstructive pulmonary disease	0.927	0.073
R00.0 Tachycardia, unspecified	0.926	0.074
I84.1 Internal haemorrhoids with other complications	0.923	0.077
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.922	0.078
I35 Nonrheumatic aortic valve disorders	0.920	0.080
E10 Insulin-dependent diabetes mellitus	0.920	0.080
D25 Leiomyoma of uterus	0.919	0.081
D12.2 Ascending colon	0.917	0.083
R53 Malaise and fatigue	0.917	0.083
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.915	0.085
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.914	0.086
D50-D53 Nutritional anaemias	0.914	0.086
R51 Headache	0.912	0.088
D12.0 Caecum	0.912	0.088
D24 Benign neoplasm of breast	0.909	0.091
Chapter I Certain infectious and parasitic diseases	0.907	0.093
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.907	0.093
I50 Heart failure	0.906	0.094
R07 Pain in throat and chest	0.905	0.095
E70-E90 Metabolic disorders	0.901	0.099
T40.2 Other opioids	0.895	0.105
Chapter XX External causes of morbidity and mortality	0.894	0.106
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.893	0.107
G81 Hemiplegia	0.891	0.109
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.886	0.114
K08 Other disorders of teeth and supporting structures	0.885	0.115
J90 Pleural effusion, not elsewhere classified	0.884	0.116
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.883	0.117
R07.4 Chest pain, unspecified	0.883	0.117
C64-C68 Malignant neoplasms of urinary tract	0.878	0.122
I46 Cardiac arrest	0.878	0.122
I84.7 Unspecified thrombosed haemorrhoids	0.874	0.126
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.870	0.130
S20-S29 Injuries to the thorax	0.866	0.134
C18 Malignant neoplasm of colon	0.865	0.135
G93 Other disorders of brain	0.860	0.140
G81.9 Hemiplegia, unspecified	0.859	0.141
R04 Haemorrhage from respiratory passages	0.857	0.143
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.857	0.143
D17.7 Benign lipomatous neoplasm of other sites	0.857	0.143
B25-B34 Other viral diseases	0.853	0.147
D50 Iron deficiency anaemia	0.853	0.147
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.851	0.149
I05-I09 Chronic rheumatic heart diseases	0.850	0.150
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.849	0.151
E87 Other disorders of fluid, electrolyte and acid-base balance	0.848	0.152
J20-J22 Other acute lower respiratory infections	0.847	0.153
G40-G47 Episodic and paroxysmal disorders	0.847	0.153
R47-R49 Symptoms and signs involving speech and voice	0.847	0.153
D32 Benign neoplasm of meninges	0.846	0.154
J93 Pneumothorax	0.840	0.160
I35.0 Aortic (valve) stenosis	0.838	0.162
I50.0 Congestive heart failure	0.833	0.167
R93 Abnormal findings on diagnostic imaging of other body structures	0.830	0.170
D25.2 Subserosal leiomyoma of uterus	0.827	0.173
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.826	0.174
E10.9 Without complications	0.824	0.176
M05-M14 Inflammatory polyarthropathies	0.822	0.178
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.822	0.178
D14 Benign neoplasm of middle ear and respiratory system	0.820	0.180
I51.7 Cardiomegaly	0.818	0.182
I84.9 Unspecified haemorrhoids without complication	0.818	0.182
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.816	0.184
B34 Viral infection of unspecified site	0.815	0.185
D37-D48 Neoplasms of uncertain or unknown behaviour	0.812	0.188
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.811	0.189
E10.3 With ophthalmic complications	0.810	0.190
J09-J18 Influenza and pneumonia	0.809	0.191
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.809	0.191
E20-E35 Disorders of other endocrine glands	0.809	0.191
I49 Other cardiac arrhythmias	0.807	0.193
I38 Endocarditis, valve unspecified	0.806	0.194
Chapter V Mental and behavioural disorders	0.806	0.194
J44.9 Chronic obstructive pulmonary disease, unspecified	0.804	0.196
R91 Abnormal findings on diagnostic imaging of lung	0.804	0.196
E11 Non-insulin-dependent diabetes mellitus	0.801	0.199
R00.1 Bradycardia, unspecified	0.801	0.199
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.797	0.203
M45-M49 Spondylopathies	0.796	0.204
T43.5 Other and unspecified antipsychotics and neuroleptics	0.796	0.204
I45 Other conduction disorders	0.796	0.204
J43 Emphysema	0.796	0.204
J60-J70 Lung diseases due to external agents	0.795	0.205
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.795	0.205
M06 Other rheumatoid arthritis	0.793	0.207
I36 Nonrheumatic tricuspid valve disorders	0.793	0.207
D50.9 Iron deficiency anaemia, unspecified	0.793	0.207
D12.3 Transverse colon	0.792	0.208
R00.2 Palpitations	0.792	0.208
I35.2 Aortic (valve) stenosis with insufficiency	0.790	0.210
R52 Pain, not elsewhere classified	0.790	0.210
D34 Benign neoplasm of thyroid gland	0.789	0.211
I51.4 Myocarditis, unspecified	0.788	0.212
B34.9 Viral infection, unspecified	0.788	0.212
I60-I69 Cerebrovascular diseases	0.787	0.213
Chapter XXII Codes for special purposes	0.786	0.214
E14 Unspecified diabetes mellitus	0.784	0.216
E50-E64 Other nutritional deficiencies	0.783	0.217
J40 Bronchitis, not specified as acute or chronic	0.782	0.218
D21 Other benign neoplasms of connective and other soft tissue	0.782	0.218
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.782	0.218
K08.3 Retained dental root	0.782	0.218
J95-J99 Other diseases of the respiratory system	0.781	0.219
I51.9 Heart disease, unspecified	0.780	0.220
S00-S09 Injuries to the head	0.779	0.221
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.778	0.222
K12 Stomatitis and related lesions	0.776	0.224
E87.6 Hypokalaemia	0.775	0.225
D69 Purpura and other haemorrhagic conditions	0.772	0.228
G90 Disorders of autonomic nervous system	0.772	0.228
I51.6 Cardiovascular disease, unspecified	0.771	0.229
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.770	0.230
I89.0 Lymphoedema, not elsewhere classified	0.769	0.231
T79-T79 Certain early complications of trauma	0.769	0.231
D28 Benign neoplasm of other and unspecified female genital organs	0.768	0.232
J80-J84 Other respiratory diseases principally affecting the interstitium	0.767	0.232
I46.0 Cardiac arrest with successful resuscitation	0.767	0.233
R23 Other skin changes	0.766	0.234
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.765	0.235
R47 Speech disturbances, not elsewhere classified	0.765	0.235
G91 Hydrocephalus	0.763	0.237
Chapter VII Diseases of the eye and adnexa	0.763	0.237
M06.9 Rheumatoid arthritis, unspecified	0.762	0.238
R41 Other symptoms and signs involving cognitive functions and awareness	0.762	0.238
C67 Malignant neoplasm of bladder	0.762	0.238
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.761	0.239
D35 Benign neoplasm of other and unspecified endocrine glands	0.761	0.239
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.760	0.240
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.759	0.241
D25.0 Submucous leiomyoma of uterus	0.757	0.243
T81 Complications of procedures, not elsewhere classified	0.756	0.244
G93.0 Cerebral cysts	0.756	0.244
D51 Vitamin B12 deficiency anaemia	0.755	0.244
R04.2 Haemoptysis	0.755	0.245
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.755	0.245
J44.8 Other specified chronic obstructive pulmonary disease	0.753	0.247
G43 Migraine	0.752	0.248
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.752	0.248
I70-I79 Diseases of arteries, arterioles and capillaries	0.752	0.248
T15-T19 Effects of foreign body entering through natural orifice	0.751	0.248
K35-K38 Diseases of appendix	0.751	0.249
J93.9 Pneumothorax, unspecified	0.751	0.249
K14 Diseases of tongue	0.751	0.249
R60 Oedema, not elsewhere classified	0.750	0.250
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.750	0.250
K04 Diseases of pulp and periapical tissues	0.749	0.251
A00-A09 Intestinal infectious diseases	0.749	0.251
J91 Pleural effusion in conditions classified elsewhere	0.744	0.256
D26 Other benign neoplasms of uterus	0.744	0.256
I84.6 Residual haemorrhoidal skin tags	0.743	0.257
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.743	0.257
R21 Rash and other nonspecific skin eruption	0.743	0.257
I69 Sequelae of cerebrovascular disease	0.743	0.257
C18.7 Sigmoid colon	0.741	0.259
I27 Other pulmonary heart diseases	0.740	0.260
J13 Pneumonia due to Streptococcus pneumoniae	0.740	0.260
S70-S79 Injuries to the hip and thigh	0.739	0.260
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.739	0.260
K09 Cysts of oral region, not elsewhere classified	0.739	0.261
J22 Unspecified acute lower respiratory infection	0.739	0.261
I87 Other disorders of veins	0.738	0.262
I35.8 Other aortic valve disorders	0.736	0.264
G00-G09 Inflammatory diseases of the central nervous system	0.734	0.266
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.732	0.268
R46 Symptoms and signs involving appearance and behaviour	0.732	0.268
J92 Pleural plaque	0.731	0.269
D69.6 Thrombocytopenia, unspecified	0.731	0.269
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.730	0.270
X60-X84 Intentional self-harm	0.729	0.271
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.728	0.272
I84.0 Internal thrombosed haemorrhoids	0.728	0.272
J46 Status asthmaticus	0.727	0.272
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.726	0.274
S90-S99 Injuries to the ankle and foot	0.726	0.274
A30-A49 Other bacterial diseases	0.726	0.274
C16 Malignant neoplasm of stomach	0.726	0.274
S22 Fracture of rib(s), sternum and thoracic spine	0.725	0.275
K07 Dentofacial anomalies [including malocclusion]	0.724	0.276
K08.2 Atrophy of edentulous alveolar ridge	0.723	0.277
T43.0 Tricyclic and tetracyclic antidepressants	0.722	0.278
I95-I99 Other and unspecified disorders of the circulatory system	0.722	0.278
C18.1 Appendix	0.722	0.278
D25.1 Intramural leiomyoma of uterus	0.722	0.278
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.722	0.278
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.721	0.279
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.721	0.279
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.720	0.280
G93.6 Cerebral oedema	0.719	0.281
T39.1 4-Aminophenol derivatives	0.719	0.281
K08.8 Other specified disorders of teeth and supporting structures	0.719	0.281
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.718	0.282
T43.2 Other and unspecified antidepressants	0.718	0.282
S40-S49 Injuries to the shoulder and upper arm	0.718	0.282
I07 Rheumatic tricuspid valve diseases	0.718	0.282
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
D31 Benign neoplasm of eye and adnexa	0.717	0.283
D30 Benign neoplasm of urinary organs	0.717	0.283
D29 Benign neoplasm of male genital organs	0.717	0.283
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.717	0.283
D19 Benign neoplasm of mesothelial tissue	0.717	0.283
D16 Benign neoplasm of bone and articular cartilage	0.717	0.283
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.717	0.283
D10 Benign neoplasm of mouth and pharynx	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
C20 Malignant neoplasm of rectum	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
G80 Infantile cerebral palsy	0.715	0.285
I52 Other heart disorders in diseases classified elsewhere	0.714	0.286
I48 Atrial fibrillation and flutter	0.714	0.286
I43 Cardiomyopathy in diseases classified elsewhere	0.714	0.286
I41 Myocarditis in diseases classified elsewhere	0.714	0.286
I40 Acute myocarditis	0.714	0.286
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.714	0.286
I37 Pulmonary valve disorders	0.714	0.286
I32 Pericarditis in diseases classified elsewhere	0.714	0.286
I30 Acute pericarditis	0.714	0.286
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.712	0.288
C18.6 Descending colon	0.712	0.288
M47 Spondylosis	0.712	0.288
E40-E46 Malnutrition	0.712	0.288
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.711	0.288
R52.1 Chronic intractable pain	0.711	0.289
E80 Disorders of porphyrin and bilirubin metabolism	0.711	0.289
C18.2 Ascending colon	0.711	0.289
D17.9 Benign lipomatous neoplasm, unspecified	0.710	0.290
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.710	0.290
G45 Transient cerebral ischaemic attacks and related syndromes	0.710	0.290
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.710	0.290
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.710	0.290
D11 Benign neoplasm of major salivary glands	0.709	0.290
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.709	0.291
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.709	0.291
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.709	0.291
T46 Poisoning by agents primarily affecting the cardiovascular system	0.709	0.291
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.709	0.291
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.709	0.291
T41 Poisoning by anaesthetics and therapeutic gases	0.709	0.291
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.709	0.291
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.709	0.291
T36 Poisoning by systemic antibiotics	0.709	0.291
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.709	0.291
G70-G73 Diseases of myoneural junction and muscle	0.709	0.291
J47 Bronchiectasis	0.709	0.291
D23 Other benign neoplasms of skin	0.709	0.291
T43.3 Phenothiazine antipsychotics and neuroleptics	0.708	0.292
R50 Fever of unknown origin	0.707	0.293
D33 Benign neoplasm of brain and other parts of central nervous system	0.707	0.293
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.706	0.294
G35-G37 Demyelinating diseases of the central nervous system	0.705	0.295
J00-J06 Acute upper respiratory infections	0.705	0.295
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.704	0.296
E11.1 With ketoacidosis	0.704	0.296
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.704	0.296
E10.1 With ketoacidosis	0.704	0.296
K20-K31 Diseases of oesophagus, stomach and duodenum	0.704	0.296
F30-F39 Mood [affective] disorders	0.704	0.296
R45 Symptoms and signs involving emotional state	0.703	0.297
I33 Acute and subacute endocarditis	0.703	0.297
S60-S69 Injuries to the wrist and hand	0.703	0.297
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.702	0.298
I88 Nonspecific lymphadenitis	0.702	0.298
I82 Other venous embolism and thrombosis	0.702	0.298
I81 Portal vein thrombosis	0.702	0.298
D60-D64 Aplastic and other anaemias	0.701	0.299
R47.0 Dysphasia and aphasia	0.701	0.299
K40-K46 Hernia	0.700	0.300
R01 Cardiac murmurs and other cardiac sounds	0.699	0.301
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.698	0.302
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.698	0.302
J41 Simple and mucopurulent chronic bronchitis	0.697	0.303
T66-T78 Other and unspecified effects of external causes	0.697	0.303
D70-D77 Other diseases of blood and blood-forming organs	0.697	0.303
M48 Other spondylopathies	0.696	0.303
I50.9 Heart failure, unspecified	0.696	0.304
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.696	0.304
G30-G32 Other degenerative diseases of the nervous system	0.694	0.306
R00.8 Other and unspecified abnormalities of heart beat	0.694	0.306
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.694	0.306
T86 Failure and rejection of transplanted organs and tissues	0.694	0.306
E13 Other specified diabetes mellitus	0.693	0.307
E12 Malnutrition-related diabetes mellitus	0.693	0.307
C64 Malignant neoplasm of kidney, except renal pelvis	0.693	0.307
K08.9 Disorder of teeth and supporting structures, unspecified	0.692	0.308
D55-D59 Haemolytic anaemias	0.692	0.308
D14.0 Middle ear, nasal cavity and accessory sinuses	0.692	0.308
I86 Varicose veins of other sites	0.691	0.309
J94 Other pleural conditions	0.691	0.309
D32.0 Cerebral meninges	0.691	0.309
G20-G26 Extrapyramidal and movement disorders	0.690	0.310
D12.8 Rectum	0.690	0.310
I46.9 Cardiac arrest, unspecified	0.688	0.312
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.686	0.314
R06 Abnormalities of breathing	0.686	0.314
E65-E68 Obesity and other hyperalimentation	0.686	0.314
I85 Oesophageal varices	0.685	0.315
E87.0 Hyperosmolality and hypernatraemia	0.685	0.315
K55-K64 Other diseases of intestines	0.685	0.315
I84.8 Unspecified haemorrhoids with other complications	0.684	0.316
J45 Asthma	0.684	0.316
D12.9 Anus and anal canal	0.683	0.317
D12.1 Appendix	0.683	0.317
R02 Gangrene, not elsewhere classified	0.683	0.317
J30-J39 Other diseases of upper respiratory tract	0.682	0.318
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.681	0.319
I27.2 Other secondary pulmonary hypertension	0.680	0.320
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.680	0.320
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.680	0.320
E87.1 Hypo-osmolality and hyponatraemia	0.679	0.321
I42 Cardiomyopathy	0.676	0.324
D32.9 Meninges, unspecified	0.675	0.325
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.675	0.325
S27 Injury of other and unspecified intrathoracic organs	0.675	0.325
E00-E07 Disorders of thyroid gland	0.674	0.326
J42 Unspecified chronic bronchitis	0.674	0.326
E87.7 Fluid overload	0.673	0.327
I51.5 Myocardial degeneration	0.673	0.327
I51.3 Intracardiac thrombosis, not elsewhere classified	0.673	0.327
I51.2 Rupture of papillary muscle, not elsewhere classified	0.673	0.327
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.673	0.327
I51.0 Cardiac septal defect, acquired	0.673	0.327
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.672	0.328
R62 Lack of expected normal physiological development	0.672	0.328
R57 Shock, not elsewhere classified	0.672	0.328
R64 Cachexia	0.672	0.328
R58 Haemorrhage, not elsewhere classified	0.672	0.328
G83 Other paralytic syndromes	0.671	0.329
G82 Paraplegia and tetraplegia	0.671	0.329
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.671	0.329
K11 Diseases of salivary glands	0.670	0.330
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.670	0.330
G96 Other disorders of central nervous system	0.670	0.330
G94 Other disorders of brain in diseases classified elsewhere	0.670	0.330
G98 Other disorders of nervous system, not elsewhere classified	0.670	0.330
G92 Toxic encephalopathy	0.670	0.330
C26 Malignant neoplasm of other and ill-defined digestive organs	0.670	0.330
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.670	0.330
C21 Malignant neoplasm of anus and anal canal	0.670	0.330
C17 Malignant neoplasm of small intestine	0.670	0.330
C23 Malignant neoplasm of gallbladder	0.670	0.330
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.670	0.330
T40.8 Lysergide [LSD]	0.670	0.330
T40.7 Cannabis (derivatives)	0.670	0.330
T40.6 Other and unspecified narcotics	0.670	0.330
T40.5 Cocaine	0.670	0.330
T40.4 Other synthetic narcotics	0.670	0.330
T40.3 Methadone	0.670	0.330
T40.1 Heroin	0.670	0.330
T40.0 Opium	0.670	0.330
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.670	0.330
J43.9 Emphysema, unspecified	0.669	0.331
A80-A89 Viral infections of the central nervous system	0.669	0.331
T81.3 Disruption of operation wound, not elsewhere classified	0.669	0.331
C81 Hodgkin's disease	0.668	0.332
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.668	0.332
I05 Rheumatic mitral valve diseases	0.668	0.332
R68 Other general symptoms and signs	0.667	0.333
C19 Malignant neoplasm of rectosigmoid junction	0.667	0.333
R09.1 Pleurisy	0.667	0.333
K12.1 Other forms of stomatitis	0.666	0.334
X40-X49 Accidental poisoning by and exposure to noxious substances	0.664	0.336
I31 Other diseases of pericardium	0.664	0.336
I84.3 External thrombosed haemorrhoids	0.663	0.337
S02 Fracture of skull and facial bones	0.662	0.338
G95 Other diseases of spinal cord	0.661	0.339
R90 Abnormal findings on diagnostic imaging of central nervous system	0.661	0.339
R92 Abnormal findings on diagnostic imaging of breast	0.661	0.339
M10 Gout	0.660	0.340
I35.9 Aortic valve disorder, unspecified	0.659	0.341
E10.8 With unspecified complications	0.659	0.341
E10.7 With multiple complications	0.659	0.341
E10.6 With other specified complications	0.659	0.341
E10.5 With peripheral circulatory complications	0.659	0.341
E10.4 With neurological complications	0.659	0.341
E10.2 With renal complications	0.659	0.341
E10.0 With coma	0.659	0.341
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.659	0.341
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.658	0.342
G43.9 Migraine, unspecified	0.658	0.342
E89.0 Postprocedural hypothyroidism	0.658	0.342
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.657	0.343
S20 Superficial injury of thorax	0.657	0.343
E88 Other metabolic disorders	0.656	0.344
T43.9 Psychotropic drug, unspecified	0.656	0.344
T43.8 Other psychotropic drugs, not elsewhere classified	0.656	0.344
T43.6 Psychostimulants with abuse potential	0.656	0.344
T43.4 Butyrophenone and thioxanthene neuroleptics	0.656	0.344
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.656	0.344
K10 Other diseases of jaws	0.655	0.344
K06 Other disorders of gingiva and edentulous alveolar ridge	0.655	0.344
K03 Other diseases of hard tissues of teeth	0.655	0.344
K00 Disorders of tooth development and eruption	0.655	0.344
D53 Other nutritional anaemias	0.655	0.345
D52 Folate deficiency anaemia	0.655	0.345
G90.9 Disorder of autonomic nervous system, unspecified	0.655	0.345
S50-S59 Injuries to the elbow and forearm	0.653	0.346
G93.9 Disorder of brain, unspecified	0.653	0.346
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.653	0.347
R09.0 Asphyxia	0.652	0.348
B99-B99 Other infectious diseases	0.650	0.350
B90-B94 Sequelae of infectious and parasitic diseases	0.650	0.350
B85-B89 Pediculosis, acariasis and other infestations	0.650	0.350
B65-B83 Helminthiases	0.650	0.350
B50-B64 Protozoal diseases	0.650	0.350
B20-B24 Human immunodeficiency virus [HIV] disease	0.650	0.350
B15-B19 Viral hepatitis	0.650	0.350
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.650	0.350
A75-A79 Rickettsioses	0.650	0.350
A70-A74 Other diseases caused by chlamydiae	0.650	0.350
A65-A69 Other spirochaetal diseases	0.650	0.350
A50-A64 Infections with a predominantly sexual mode of transmission	0.650	0.350
A20-A28 Certain zoonotic bacterial diseases	0.650	0.350
A15-A19 Tuberculosis	0.650	0.350
T87 Complications peculiar to reattachment and amputation	0.650	0.350
T80 Complications following infusion, transfusion and therapeutic injection	0.650	0.350
H52 Disorders of refraction and accommodation	0.649	0.351
J69 Pneumonitis due to solids and liquids	0.649	0.351
R07.1 Chest pain on breathing	0.649	0.351
K05 Gingivitis and periodontal diseases	0.648	0.352
I84.4 External haemorrhoids with other complications	0.648	0.352
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.648	0.352
H30-H36 Disorders of choroid and retina	0.647	0.353
R40 Somnolence, stupor and coma	0.647	0.353
R61 Hyperhidrosis	0.647	0.353
I49.9 Cardiac arrhythmia, unspecified	0.646	0.353
G44 Other headache syndromes	0.646	0.354
E85 Amyloidosis	0.646	0.354
E84 Cystic fibrosis	0.646	0.354
E79 Disorders of purine and pyrimidine metabolism	0.646	0.354
E77 Disorders of glycoprotein metabolism	0.646	0.354
E76 Disorders of glycosaminoglycan metabolism	0.646	0.354
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.646	0.354
E74 Other disorders of carbohydrate metabolism	0.646	0.354
E73 Lactose intolerance	0.646	0.354
E72 Other disorders of amino-acid metabolism	0.646	0.354
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.646	0.354
E70 Disorders of aromatic amino-acid metabolism	0.646	0.354
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.646	0.354
Y60-Y69 Misadventures to patients during surgical and medical care	0.645	0.354
D80-D89 Certain disorders involving the immune mechanism	0.645	0.355
I49.8 Other specified cardiac arrhythmias	0.645	0.355
V10-V19 Pedal cyclist injured in transport accident	0.645	0.355
K81 Cholecystitis	0.644	0.355
M06.0 Seronegative rheumatoid arthritis	0.643	0.357
K70-K77 Diseases of liver	0.642	0.358
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.641	0.359
Y35-Y36 Legal intervention and operations of war	0.641	0.359
Y10-Y34 Event of undetermined intent	0.641	0.359
Y00-Y09 Assault	0.641	0.359
X85-X99 Assault	0.641	0.359
X58-X59 Accidental exposure to other and unspecified factors	0.641	0.359
X50-X57 Overexertion, travel and privation	0.641	0.359
X30-X39 Exposure to forces of nature	0.641	0.359
X20-X29 Contact with venomous animals and plants	0.641	0.359
X10-X19 Contact with heat and hot substances	0.641	0.359
X00-X09 Exposure to smoke, fire and flames	0.641	0.359
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.641	0.359
W75-W84 Other accidental threats to breathing	0.641	0.359
W65-W74 Accidental drowning and submersion	0.641	0.359
W50-W64 Exposure to animate mechanical forces	0.641	0.359
V98-V99 Other and unspecified transport accidents	0.641	0.359
V95-V97 Air and space transport accidents	0.641	0.359
V90-V94 Water transport accidents	0.641	0.359

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations