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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72745400
log Bayes Factor = 16.2767
Chromosome 1   position 217,672,512  (GRCh37) Explore rs72745400 on Ensembl!
Variant rs72745400 is part of Cluster X0155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I20 Angina pectoris
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
I20.0 Unstable angina
0.997 0.003 0.000
I25.1 Atherosclerotic heart disease
0.996 0.004 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
J44 Other chronic obstructive pulmonary disease
0.991 0.009 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.985 0.015 0.000
O60-O75 Complications of labour and delivery
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
S00-S09 Injuries to the head
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.967 0.033 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.967 0.033 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.965 0.035 0.000
Chapter XXI Factors influencing health status and contact with health services
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.956 0.044 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.951 0.049 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.947 0.053 0.000
L03 Cellulitis
0.943 0.057 0.000
Z60 Problems related to social environment
0.937 0.063 0.000
Z60.2 Living alone
0.930 0.070 0.000
S09 Other and unspecified injuries of head
0.929 0.071 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.928 0.072 0.000
F41 Other anxiety disorders
0.926 0.074 0.000
G90-G99 Other disorders of the nervous system
0.914 0.086 0.000
M45-M49 Spondylopathies
0.911 0.089 0.000
M70-M79 Other soft tissue disorders
0.911 0.089 0.000
E65-E68 Obesity and other hyperalimentation
0.911 0.089 0.000
L03.1 Cellulitis of other parts of limb
0.906 0.094 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.906 0.094 0.000
I20.9 Angina pectoris, unspecified
0.901 0.099 0.000
O72 Postpartum haemorrhage
0.900 0.100 0.000
F41.9 Anxiety disorder, unspecified
0.896 0.104 0.000
S80-S89 Injuries to the knee and lower leg
0.893 0.107 0.000
S01 Open wound of head
0.893 0.107 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.893 0.107 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.892 0.108 0.000
Chapter XIV Diseases of the genitourinary system
0.892 0.108 0.000
S09.9 Unspecified injury of head
0.892 0.108 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.887 0.113 0.000
I30-I52 Other forms of heart disease
0.886 0.114 0.000
M50-M54 Other dorsopathies
0.883 0.117 0.000
G40-G47 Episodic and paroxysmal disorders
0.881 0.119 0.000
E66 Obesity
0.879 0.121 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.878 0.122 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.877 0.123 0.000
I25.2 Old myocardial infarction
0.875 0.125 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.874 0.126 0.000
N30-N39 Other diseases of urinary system
0.870 0.130 0.000
M50 Cervical disk disorders
0.860 0.140 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.857 0.143 0.000
N39 Other disorders of urinary system
0.855 0.145 0.000
E20-E35 Disorders of other endocrine glands
0.852 0.148 0.000
J90-J94 Other diseases of pleura
0.850 0.150 0.000
E66.9 Obesity, unspecified
0.850 0.150 0.000
J95-J99 Other diseases of the respiratory system
0.846 0.154 0.000
M47 Spondylosis
0.842 0.158 0.000
O72.1 Other immediate postpartum haemorrhage
0.840 0.160 0.000
M75 Shoulder lesions
0.836 0.164 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.831 0.169 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.830 0.170 0.000
J09-J18 Influenza and pneumonia
0.827 0.173 0.000
Chapter VIII Diseases of the ear and mastoid process
0.825 0.175 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.825 0.175 0.000
G20-G26 Extrapyramidal and movement disorders
0.822 0.178 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.820 0.180 0.000
L03.2 Cellulitis of face
0.818 0.182 0.000
G93 Other disorders of brain
0.818 0.182 0.000
F30-F39 Mood [affective] disorders
0.814 0.186 0.000
N39.3 Stress incontinence
0.812 0.188 0.000
G40 Epilepsy
0.808 0.192 0.000
O66 Other obstructed labour
0.808 0.192 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.807 0.193 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.807 0.193 0.000
T66-T78 Other and unspecified effects of external causes
0.806 0.194 0.000
I51 Complications and ill-defined descriptions of heart disease
0.806 0.194 0.000
S01.9 Open wound of head, part unspecified
0.806 0.194 0.000
S20-S29 Injuries to the thorax
0.805 0.195 0.000
I10-I15 Hypertensive diseases
0.804 0.196 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.804 0.196 0.000
J30-J39 Other diseases of upper respiratory tract
0.801 0.199 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.801 0.199 0.000
J43 Emphysema
0.800 0.200 0.000
L20-L30 Dermatitis and eczema
0.793 0.207 0.000
J46 Status asthmaticus
0.793 0.207 0.000
T43.2 Other and unspecified antidepressants
0.792 0.208 0.000
M65-M68 Disorders of synovium and tendon
0.790 0.210 0.000
M46 Other inflammatory spondylopathies
0.782 0.218 0.000
M50.2 Other cervical disk displacement
0.780 0.220 0.000
F60-F69 Disorders of adult personality and behaviour
0.779 0.221 0.000
Chapter XX External causes of morbidity and mortality
0.777 0.223 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.777 0.223 0.000
I60-I69 Cerebrovascular diseases
0.775 0.225 0.000
M50.1 Cervical disk disorder with radiculopathy
0.774 0.226 0.000
M75.0 Adhesive capsulitis of shoulder
0.772 0.228 0.000
L08 Other local infections of skin and subcutaneous tissue
0.772 0.228 0.000
J42 Unspecified chronic bronchitis
0.770 0.230 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.767 0.233 0.000
T39.0 Salicylates
0.766 0.234 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.761 0.239 0.000
F99-F99 Unspecified mental disorder
0.760 0.240 0.000
G95 Other diseases of spinal cord
0.758 0.242 0.000
N25-N29 Other disorders of kidney and ureter
0.758 0.242 0.000
J60-J70 Lung diseases due to external agents
0.756 0.244 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.756 0.244 0.000
M47.9 Spondylosis, unspecified
0.755 0.245 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.754 0.246 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.754 0.246 0.000
N39.4 Other specified urinary incontinence
0.753 0.246 0.000
T39.1 4-Aminophenol derivatives
0.753 0.247 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.752 0.248 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.752 0.248 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.752 0.248 0.000
J40 Bronchitis, not specified as acute or chronic
0.752 0.248 0.000
Chapter XXII Codes for special purposes
0.751 0.249 0.000
I12 Hypertensive renal disease
0.748 0.252 0.000
S40-S49 Injuries to the shoulder and upper arm
0.748 0.252 0.000
S00 Superficial injury of head
0.746 0.254 0.000
I34 Nonrheumatic mitral valve disorders
0.746 0.254 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.745 0.255 0.000
G40.9 Epilepsy, unspecified
0.745 0.255 0.000
J47 Bronchiectasis
0.744 0.256 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
O16 Unspecified maternal hypertension
0.742 0.258 0.000
S82 Fracture of lower leg, including ankle
0.741 0.259 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.741 0.259 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
L40-L45 Papulosquamous disorders
0.739 0.261 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.263 0.000
Z34 Supervision of normal pregnancy
0.736 0.264 0.000
M91-M94 Chondropathies
0.735 0.265 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.734 0.266 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.734 0.266 0.000
I51.8 Other ill-defined heart diseases
0.732 0.268 0.000
S01.0 Open wound of scalp
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.731 0.269 0.000
I22 Subsequent myocardial infarction
0.730 0.270 0.000
G70-G73 Diseases of myoneural junction and muscle
0.729 0.271 0.000
R50-R69 General symptoms and signs
0.729 0.271 0.000
L05 Pilonidal cyst
0.728 0.272 0.000
O63 Long labour
0.728 0.272 0.000
O00-O08 Pregnancy with abortive outcome
0.727 0.273 0.000
M50.3 Other cervical disk degeneration
0.726 0.274 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.726 0.274 0.000
M77 Other enthesopathies
0.725 0.275 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.724 0.276 0.000
O80-O84 Delivery
0.722 0.278 0.000
S06 Intracranial injury
0.722 0.278 0.000
O62 Abnormalities of forces of labour
0.722 0.278 0.000
Z63 Other problems related to primary support group, including family circumstances
0.720 0.280 0.000
N35 Urethral stricture
0.720 0.280 0.000
R55 Syncope and collapse
0.720 0.280 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.718 0.282 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.717 0.283 0.000
E00-E07 Disorders of thyroid gland
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I20.1 Angina pectoris with documented spasm
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.714 0.286 0.000
I21 Acute myocardial infarction
0.713 0.287 0.000
L50-L54 Urticaria and erythema
0.712 0.288 0.000
G62 Other polyneuropathies
0.711 0.289 0.000
L03.3 Cellulitis of trunk
0.711 0.289 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.711 0.289 0.000
F33 Recurrent depressive disorder
0.710 0.290 0.000
H90-H95 Other disorders of ear
0.710 0.290 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
G93.8 Other specified disorders of brain
0.708 0.292 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.708 0.292 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
J18 Pneumonia, organism unspecified
0.706 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F80-F89 Disorders of psychological development
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.706 0.294 0.000
O74 Complications of anaesthesia during labour and delivery
0.706 0.294 0.000
O73 Retained placenta and membranes, without haemorrhage
0.706 0.294 0.000
O71 Other obstetric trauma
0.706 0.294 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.706 0.294 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.706 0.294 0.000
O61 Failed induction of labour
0.706 0.294 0.000
O60 Preterm delivery
0.706 0.294 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.705 0.295 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.705 0.295 0.000
R51 Headache
0.705 0.295 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.705 0.295 0.000
J92 Pleural plaque
0.704 0.296 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.703 0.297 0.000
I20.8 Other forms of angina pectoris
0.703 0.297 0.000
E50-E64 Other nutritional deficiencies
0.703 0.297 0.000
S08 Traumatic amputation of part of head
0.703 0.297 0.000
S07 Crushing injury of head
0.703 0.297 0.000
S05 Injury of eye and orbit
0.703 0.297 0.000
S04 Injury of cranial nerves
0.703 0.297 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.703 0.297 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.703 0.297 0.000
M60-M63 Disorders of muscles
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.702 0.298 0.000
S81 Open wound of lower leg
0.702 0.298 0.000
N39.9 Disorder of urinary system, unspecified
0.700 0.300 0.000
L60-L75 Disorders of skin appendages
0.699 0.301 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.698 0.302 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.697 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.697 0.303 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.696 0.304 0.000
F40 Phobic anxiety disorders
0.694 0.306 0.000
O36 Maternal care for other known or suspected foetal problems
0.694 0.306 0.000
Z53.8 Procedure not carried out for other reasons
0.694 0.306 0.000
L04 Acute lymphadenitis
0.693 0.307 0.000
L01 Impetigo
0.693 0.307 0.000
L00 Staphylococcal scalded skin syndrome
0.693 0.307 0.000
M75.2 Bicipital tendinitis
0.692 0.308 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.308 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.692 0.308 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.692 0.308 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.692 0.308 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.308 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.692 0.308 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
T36 Poisoning by systemic antibiotics
0.692 0.308 0.000
O41 Other disorders of amniotic fluid and membranes
0.691 0.309 0.000
E28 Ovarian dysfunction
0.690 0.309 0.000
J80 Adult respiratory distress syndrome
0.690 0.310 0.000
G20 Parkinson's disease
0.690 0.310 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.689 0.311 0.000
F41.2 Mixed anxiety and depressive disorder
0.689 0.311 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.689 0.311 0.000
J98 Other respiratory disorders
0.689 0.311 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.688 0.311 0.000
Z31 Procreative management
0.688 0.311 0.000
Z36 Antenatal screening
0.688 0.312 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.687 0.313 0.000
M40-M43 Deforming dorsopathies
0.686 0.314 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.686 0.314 0.000
I30 Acute pericarditis
0.685 0.315 0.000
E40-E46 Malnutrition
0.685 0.315 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.315 0.000
F43 Reaction to severe stress, and adjustment disorders
0.685 0.315 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.685 0.315 0.000
I42 Cardiomyopathy
0.684 0.316 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.684 0.316 0.000
E66.8 Other obesity
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.682 0.318 0.000
F48 Other neurotic disorders
0.682 0.318 0.000
F45 Somatoform disorders
0.682 0.318 0.000
F44 Dissociative [conversion] disorders
0.682 0.318 0.000
F42 Obsessive-compulsive disorder
0.682 0.318 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.681 0.319 0.000
I05-I09 Chronic rheumatic heart diseases
0.681 0.319 0.000
S02 Fracture of skull and facial bones
0.680 0.320 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.680 0.320 0.000
M47.8 Other spondylosis
0.680 0.320 0.000
Z50 Care involving use of rehabilitation procedures
0.680 0.320 0.000
I67 Other cerebrovascular diseases
0.679 0.321 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.679 0.321 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.679 0.321 0.000
Z65 Problems related to other psychosocial circumstances
0.679 0.321 0.000
Z64 Problems related to certain psychosocial circumstances
0.679 0.321 0.000
Z62 Other problems related to upbringing
0.679 0.321 0.000
Z61 Problems related to negative life events in childhood
0.679 0.321 0.000
Z59 Problems related to housing and economic circumstances
0.679 0.321 0.000
Z58 Problems related to physical environment
0.679 0.321 0.000
Z56 Problems related to employment and unemployment
0.679 0.321 0.000
Z55 Problems related to education and literacy
0.679 0.321 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.678 0.322 0.000
N36 Other disorders of urethra
0.678 0.322 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.678 0.322 0.000
I50 Heart failure
0.677 0.323 0.000
S60-S69 Injuries to the wrist and hand
0.677 0.323 0.000
L03.9 Cellulitis, unspecified
0.676 0.324 0.000
L03.8 Cellulitis of other sites
0.676 0.324 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.676 0.324 0.000
G47 Sleep disorders
0.676 0.324 0.000
N39.0 Urinary tract infection, site not specified
0.675 0.325 0.000
M75.5 Bursitis of shoulder
0.675 0.325 0.000
O30 Multiple gestation
0.675 0.325 0.000
N99-N99 Other disorders of the genitourinary system
0.675 0.325 0.000
S89 Other and unspecified injuries of lower leg
0.674 0.326 0.000
I33 Acute and subacute endocarditis
0.674 0.326 0.000
I46 Cardiac arrest
0.672 0.328 0.000
G91 Hydrocephalus
0.672 0.328 0.000
Z60.9 Problem related to social environment, unspecified
0.672 0.328 0.000
Z60.8 Other problems related to social environment
0.672 0.328 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.672 0.328 0.000
Z60.4 Social exclusion and rejection
0.672 0.328 0.000
Z60.3 Acculturation difficulty
0.672 0.328 0.000
Z60.1 Atypical parenting situation
0.672 0.328 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.672 0.328 0.000
S01.8 Open wound of other parts of head
0.671 0.328 0.000
M80-M85 Disorders of bone density and structure
0.670 0.330 0.000
J18.9 Pneumonia, unspecified
0.669 0.331 0.000
T51 Toxic effect of alcohol
0.669 0.331 0.000
T78 Adverse effects, not elsewhere classified
0.667 0.333 0.000
G30-G32 Other degenerative diseases of the nervous system
0.666 0.334 0.000
S09.8 Other specified injuries of head
0.666 0.334 0.000
S09.7 Multiple injuries of head
0.666 0.334 0.000
S09.2 Traumatic rupture of ear drum
0.666 0.334 0.000
S09.1 Injury of muscle and tendon of head
0.666 0.334 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.666 0.334 0.000
S01.3 Open wound of ear
0.666 0.334 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.665 0.335 0.000
J38.3 Other diseases of vocal cords
0.665 0.335 0.000
N17-N19 Renal failure
0.664 0.336 0.000
Z37 Outcome of delivery
0.664 0.336 0.000
F41.8 Other specified anxiety disorders
0.664 0.336 0.000
F41.3 Other mixed anxiety disorders
0.664 0.336 0.000
F41.1 Generalised anxiety disorder
0.664 0.336 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.662 0.338 0.000
J93 Pneumothorax
0.662 0.338 0.000
J30 Vasomotor and allergic rhinitis
0.662 0.338 0.000
I24 Other acute ischaemic heart diseases
0.661 0.338 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.661 0.338 0.000
Z39 Postpartum care and examination
0.660 0.340 0.000
J43.9 Emphysema, unspecified
0.660 0.340 0.000
I12.0 Hypertensive renal disease with renal failure
0.658 0.342 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.658 0.342 0.000
N30 Cystitis
0.657 0.343 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.655 0.344 0.000
G96 Other disorders of central nervous system
0.655 0.344 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.655 0.344 0.000
G90 Disorders of autonomic nervous system
0.655 0.344 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.655 0.344 0.000
G92 Toxic encephalopathy
0.655 0.344 0.000
F31 Bipolar affective disorder
0.655 0.345 0.000
G44 Other headache syndromes
0.654 0.345 0.000
G93.6 Cerebral oedema
0.654 0.345 0.000
I12.9 Hypertensive renal disease without renal failure
0.654 0.346 0.000
G93.9 Disorder of brain, unspecified
0.654 0.346 0.000
M49 Spondylopathies in diseases classified elsewhere
0.653 0.346 0.000
N60-N64 Disorders of breast
0.654 0.346 0.000
M76 Enthesopathies of lower limb, excluding foot
0.653 0.347 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.653 0.347 0.000
M71 Other bursopathies
0.653 0.347 0.000
E67 Other hyperalimentation
0.653 0.347 0.000
E68 Sequelae of hyperalimentation
0.653 0.347 0.000
E65 Localised adiposity
0.653 0.347 0.000
I35 Nonrheumatic aortic valve disorders
0.652 0.348 0.000
Z57 Occupational exposure to risk-factors
0.651 0.348 0.000
O15 Eclampsia
0.650 0.350 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.650 0.350 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.650 0.350 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.650 0.350 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.650 0.350 0.000
N10-N16 Renal tubulo-interstitial diseases
0.646 0.354 0.000
L29 Pruritus
0.646 0.354 0.000
O72.3 Postpartum coagulation defects
0.646 0.354 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.646 0.354 0.000
O72.0 Third-stage haemorrhage
0.646 0.354 0.000
S80 Superficial injury of lower leg
0.645 0.355 0.000
O26.8 Other specified pregnancy-related conditions
0.645 0.355 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.644 0.356 0.000
L03.0 Cellulitis of finger and toe
0.642 0.358 0.000
E23 Hypofunction and other disorders of pituitary gland
0.641 0.359 0.000
H60-H62 Diseases of external ear
0.641 0.359 0.000
M47.2 Other spondylosis with radiculopathy
0.641 0.359 0.000
M15-M19 Arthrosis
0.641 0.359 0.000
S88 Traumatic amputation of lower leg
0.640 0.359 0.000
S87 Crushing injury of lower leg
0.640 0.359 0.000
S86 Injury of muscle and tendon at lower leg level
0.640 0.359 0.000
S85 Injury of blood vessels at lower leg level
0.640 0.359 0.000
S84 Injury of nerves at lower leg level
0.640 0.359 0.000
S01.7 Multiple open wounds of head
0.640 0.360 0.000
S01.4 Open wound of cheek and temporomandibular area
0.640 0.360 0.000
S01.2 Open wound of nose
0.640 0.360 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.640 0.360 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.640 0.360 0.000
T39.4 Antirheumatics, not elsewhere classified
0.640 0.360 0.000
T39.2 Pyrazolone derivatives
0.640 0.360 0.000
R07 Pain in throat and chest
0.639 0.361 0.000
J35 Chronic diseases of tonsils and adenoids
0.639 0.361 0.000
R05 Cough
0.638 0.362 0.000
E29 Testicular dysfunction
0.638 0.362 0.000
S50-S59 Injuries to the elbow and forearm
0.637 0.363 0.000
F33.9 Recurrent depressive disorder, unspecified
0.636 0.364 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.636 0.364 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.636 0.364 0.000
I52 Other heart disorders in diseases classified elsewhere
0.635 0.365 0.000
I48 Atrial fibrillation and flutter
0.635 0.365 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.635 0.365 0.000
I41 Myocarditis in diseases classified elsewhere
0.635 0.365 0.000
I40 Acute myocarditis
0.635 0.365 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.635 0.365 0.000
I37 Pulmonary valve disorders
0.635 0.365 0.000
I36 Nonrheumatic tricuspid valve disorders
0.635 0.365 0.000
I32 Pericarditis in diseases classified elsewhere
0.635 0.365 0.000
Z33 Pregnant state, incidental
0.634 0.366 0.000
E27 Other disorders of adrenal gland
0.634 0.366 0.000
M53 Other dorsopathies, not elsewhere classified
0.633 0.367 0.000
Z40 Prophylactic surgery
0.633 0.367 0.000
J90 Pleural effusion, not elsewhere classified
0.633 0.367 0.000
J92.9 Pleural plaque without asbestos
0.632 0.368 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.632 0.368 0.000
G41 Status epilepticus
0.632 0.368 0.000
F60 Specific personality disorders
0.631 0.369 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.630 0.370 0.000
E66.1 Drug-induced obesity
0.630 0.370 0.000
E66.0 Obesity due to excess calories
0.630 0.370 0.000
H80-H83 Diseases of inner ear
0.630 0.370 0.000
J81 Pulmonary oedema
0.629 0.370 0.000
O45 Premature separation of placenta [abruptio placentae]
0.629 0.371 0.000
O44 Placenta praevia
0.629 0.371 0.000
O43 Placental disorders
0.629 0.371 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.629 0.371 0.000
O33 Maternal care for known or suspected disproportion
0.629 0.371 0.000
O31 Complications specific to multiple gestation
0.629 0.371 0.000
O40 Polyhydramnios
0.629 0.371 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.628 0.372 0.000
L28 Lichen simplex chronicus and prurigo
0.627 0.373 0.000
T43.9 Psychotropic drug, unspecified
0.626 0.374 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.626 0.374 0.000
T43.6 Psychostimulants with abuse potential
0.626 0.374 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.626 0.374 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.626 0.374 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.626 0.374 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.626 0.374 0.000
I31 Other diseases of pericardium
0.626 0.374 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.626 0.374 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.626 0.374 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.625 0.375 0.000
M67 Other disorders of synovium and tendon
0.625 0.375 0.000
I51.9 Heart disease, unspecified
0.624 0.376 0.000
N37 Urethral disorders in diseases classified elsewhere
0.624 0.376 0.000
N34 Urethritis and urethral syndrome
0.624 0.376 0.000
N33 Bladder disorders in diseases classified elsewhere
0.624 0.376 0.000
I34.0 Mitral (valve) insufficiency
0.623 0.377 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.622 0.378 0.000
O48 Prolonged pregnancy
0.622 0.378 0.000
Z34.8 Supervision of other normal pregnancy
0.621 0.378 0.000
J20-J22 Other acute lower respiratory infections
0.621 0.379 0.000
G43 Migraine
0.621 0.379 0.000
M45 Ankylosing spondylitis
0.620 0.380 0.000
M75.4 Impingement syndrome of shoulder
0.620 0.380 0.000
G24 Dystonia
0.619 0.380 0.000
M50.9 Cervical disk disorder, unspecified
0.616 0.383 0.000
M50.8 Other cervical disk disorders
0.616 0.383 0.000
Z38 Liveborn infants according to place of birth
0.615 0.385 0.000
Z32 Pregnancy examination and test
0.615 0.385 0.000
E10-E14 Diabetes mellitus
0.615 0.385 0.000
I11 Hypertensive heart disease
0.613 0.387 0.000
N35.9 Urethral stricture, unspecified
0.613 0.387 0.000
N39.2 Orthostatic proteinuria, unspecified
0.613 0.387 0.000
N39.1 Persistent proteinuria, unspecified
0.613 0.387 0.000
L40 Psoriasis
0.612 0.387 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.611 0.389 0.000
E34 Other endocrine disorders
0.611 0.389 0.000
E32 Diseases of thymus
0.611 0.389 0.000
E31 Polyglandular dysfunction
0.611 0.389 0.000
E30 Disorders of puberty, not elsewhere classified
0.611 0.389 0.000
E26 Hyperaldosteronism
0.611 0.389 0.000
E25 Adrenogenital disorders
0.611 0.389 0.000
E24 Cushing's syndrome
0.611 0.389 0.000
E22 Hyperfunction of pituitary gland
0.611 0.389 0.000
E20 Hypoparathyroidism
0.611 0.389 0.000
J36 Peritonsillar abscess
0.611 0.389 0.000
Z35 Supervision of high-risk pregnancy
0.610 0.390 0.000
G95.2 Cord compression, unspecified
0.610 0.390 0.000
J94 Other pleural conditions
0.610 0.390 0.000
N40-N51 Diseases of male genital organs
0.609 0.391 0.000
J38.4 Oedema of larynx
0.608 0.391 0.000
R60 Oedema, not elsewhere classified
0.607 0.393 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.606 0.393 0.000
J96 Respiratory failure, not elsewhere classified
0.606 0.393 0.000
M65 Synovitis and tenosynovitis
0.606 0.394 0.000
S01.5 Open wound of lip and oral cavity
0.605 0.395 0.000
R06 Abnormalities of breathing
0.604 0.396 0.000
M47.1 Other spondylosis with myelopathy
0.604 0.396 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.604 0.396 0.000
T92 Sequelae of injuries of upper limb
0.603 0.397 0.000
J91 Pleural effusion in conditions classified elsewhere
0.603 0.397 0.000
I60 Subarachnoid haemorrhage
0.601 0.399 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.600 0.400 0.000
E04 Other non-toxic goitre
0.600 0.400 0.000
S82.4 Fracture of fibula alone
0.600 0.400 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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