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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72780357
log Bayes Factor = 18.1647
Chromosome 5   position 110,665,372  (GRCh37) Explore rs72780357 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
M45-M49 Spondylopathies
0.991 0.009 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
M47 Spondylosis
0.986 0.014 0.000
M54 Dorsalgia
0.983 0.017 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
J44 Other chronic obstructive pulmonary disease
0.982 0.018 0.000
Chapter V Mental and behavioural disorders
0.981 0.019 0.000
D60-D64 Aplastic and other anaemias
0.975 0.025 0.000
K90-K93 Other diseases of the digestive system
0.974 0.026 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.972 0.028 0.000
J95-J99 Other diseases of the respiratory system
0.972 0.028 0.000
M51 Other intervertebral disk disorders
0.971 0.029 0.000
K50-K52 Noninfective enteritis and colitis
0.971 0.029 0.000
M13 Other arthritis
0.966 0.034 0.000
M54.5 Low back pain
0.965 0.035 0.000
D64 Other anaemias
0.963 0.037 0.000
M47.8 Other spondylosis
0.962 0.038 0.000
K92 Other diseases of digestive system
0.955 0.045 0.000
D64.9 Anaemia, unspecified
0.955 0.045 0.000
Chapter II Neoplasms
0.954 0.046 0.000
M54.59 Low back pain (Site unspecified)
0.949 0.051 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.946 0.054 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.944 0.056 0.000
M51.2 Other specified intervertebral disk displacement
0.943 0.057 0.000
J98 Other respiratory disorders
0.941 0.059 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.940 0.060 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.937 0.063 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.936 0.064 0.000
M47.82 Other spondylosis (Cervical region)
0.934 0.066 0.000
J09-J18 Influenza and pneumonia
0.933 0.067 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.932 0.068 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.931 0.069 0.000
K92.0 Haematemesis
0.931 0.069 0.000
M47.9 Spondylosis, unspecified
0.930 0.070 0.000
M13.9 Arthritis, unspecified
0.930 0.070 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.929 0.071 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.928 0.072 0.000
Chapter XX External causes of morbidity and mortality
0.927 0.073 0.000
S80-S89 Injuries to the knee and lower leg
0.924 0.076 0.000
J98.1 Pulmonary collapse
0.918 0.082 0.000
M15-M19 Arthrosis
0.911 0.089 0.000
K50 Crohn's disease [regional enteritis]
0.909 0.091 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.909 0.091 0.000
F30-F39 Mood [affective] disorders
0.908 0.092 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.908 0.092 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.905 0.095 0.000
K25 Gastric ulcer
0.902 0.098 0.000
Chapter VI Diseases of the nervous system
0.898 0.102 0.000
J43 Emphysema
0.897 0.103 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.891 0.109 0.000
J18 Pneumonia, organism unspecified
0.887 0.113 0.000
M06 Other rheumatoid arthritis
0.883 0.117 0.000
J00-J06 Acute upper respiratory infections
0.879 0.121 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.876 0.124 0.000
M10 Gout
0.874 0.126 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.873 0.127 0.000
K52 Other non-infective gastro-enteritis and colitis
0.870 0.130 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.867 0.133 0.000
J90-J94 Other diseases of pleura
0.865 0.135 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.863 0.137 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.861 0.139 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.860 0.140 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.859 0.141 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.855 0.145 0.000
K22 Other diseases of oesophagus
0.853 0.147 0.000
R07 Pain in throat and chest
0.850 0.150 0.000
Z03.8 Observation for other suspected diseases and conditions
0.847 0.153 0.000
T81 Complications of procedures, not elsewhere classified
0.846 0.154 0.000
Z92 Personal history of medical treatment
0.844 0.156 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.843 0.157 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.842 0.158 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.840 0.160 0.000
K29 Gastritis and duodenitis
0.839 0.161 0.000
M70-M79 Other soft tissue disorders
0.839 0.161 0.000
J18.1 Lobar pneumonia, unspecified
0.837 0.163 0.000
Chapter XIV Diseases of the genitourinary system
0.835 0.165 0.000
Z53.0 Procedure not carried out because of contraindication
0.835 0.165 0.000
J43.9 Emphysema, unspecified
0.829 0.171 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.828 0.172 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.825 0.175 0.000
K04 Diseases of pulp and periapical tissues
0.825 0.175 0.000
M50 Cervical disk disorders
0.824 0.175 0.000
F31 Bipolar affective disorder
0.823 0.177 0.000
S50-S59 Injuries to the elbow and forearm
0.821 0.179 0.000
K29.7 Gastritis, unspecified
0.820 0.180 0.000
K50.9 Crohn's disease, unspecified
0.820 0.180 0.000
J40 Bronchitis, not specified as acute or chronic
0.820 0.180 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.819 0.181 0.000
C15-C26 Malignant neoplasms of digestive organs
0.819 0.181 0.000
Z50 Care involving use of rehabilitation procedures
0.819 0.181 0.000
M13.0 Polyarthritis, unspecified
0.818 0.182 0.000
Z93 Artificial opening status
0.817 0.182 0.000
Z53.9 Procedure not carried out, unspecified reason
0.817 0.183 0.000
K22.7 Barrett's oesophagus
0.817 0.183 0.000
M16 Coxarthrosis [arthrosis of hip]
0.816 0.184 0.000
K65-K67 Diseases of peritoneum
0.816 0.184 0.000
C34 Malignant neoplasm of bronchus and lung
0.815 0.185 0.000
K55-K64 Other diseases of intestines
0.814 0.186 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.813 0.187 0.000
K12 Stomatitis and related lesions
0.812 0.188 0.000
R26 Abnormalities of gait and mobility
0.811 0.189 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.809 0.191 0.000
R07.3 Other chest pain
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.807 0.193 0.000
Z03.1 Observation for suspected malignant neoplasm
0.805 0.195 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.803 0.197 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.803 0.197 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.800 0.200 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.799 0.201 0.000
M19 Other arthrosis
0.799 0.201 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.797 0.203 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.796 0.204 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.796 0.204 0.000
M06.9 Rheumatoid arthritis, unspecified
0.795 0.205 0.000
R25 Abnormal involuntary movements
0.795 0.205 0.000
Chapter I Certain infectious and parasitic diseases
0.795 0.205 0.000
Z99.3 Dependence on wheelchair
0.793 0.207 0.000
S90-S99 Injuries to the ankle and foot
0.792 0.208 0.000
E70-E90 Metabolic disorders
0.792 0.208 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.792 0.208 0.000
M54.9 Dorsalgia, unspecified
0.791 0.208 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.791 0.209 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.790 0.210 0.000
K92.1 Melaena
0.790 0.210 0.000
M10.9 Gout, unspecified
0.788 0.212 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.785 0.215 0.000
J42 Unspecified chronic bronchitis
0.785 0.215 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.784 0.216 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.783 0.217 0.000
K50.1 Crohn's disease of large intestine
0.781 0.219 0.000
D62 Acute posthaemorrhagic anaemia
0.781 0.219 0.000
J93 Pneumothorax
0.781 0.219 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.781 0.219 0.000
M47.86 Other spondylosis (Lumbar region)
0.779 0.221 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.779 0.221 0.000
F33 Recurrent depressive disorder
0.777 0.223 0.000
T79-T79 Certain early complications of trauma
0.776 0.224 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.775 0.225 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.774 0.226 0.000
M80-M85 Disorders of bone density and structure
0.772 0.228 0.000
M47.2 Other spondylosis with radiculopathy
0.770 0.230 0.000
Z03.4 Observation for suspected myocardial infarction
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.768 0.232 0.000
Y43 Primarily systemic agents
0.767 0.233 0.000
Z87 Personal history of other diseases and conditions
0.767 0.233 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.766 0.234 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.766 0.234 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.765 0.235 0.000
K14 Diseases of tongue
0.765 0.235 0.000
D61 Other aplastic anaemias
0.764 0.236 0.000
F17.1 Harmful use
0.761 0.239 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.760 0.240 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.759 0.241 0.000
M79.0 Rheumatism, unspecified
0.759 0.241 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.758 0.242 0.000
S81 Open wound of lower leg
0.758 0.242 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.757 0.242 0.000
M91-M94 Chondropathies
0.757 0.243 0.000
Z45 Adjustment and management of implanted device
0.756 0.244 0.000
G40-G47 Episodic and paroxysmal disorders
0.756 0.244 0.000
R07.4 Chest pain, unspecified
0.756 0.244 0.000
K04.6 Periapical abscess with sinus
0.753 0.247 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.753 0.247 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.750 0.250 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.750 0.250 0.000
D80-D89 Certain disorders involving the immune mechanism
0.748 0.252 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.747 0.252 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.747 0.253 0.000
K40-K46 Hernia
0.746 0.254 0.000
M86-M90 Other osteopathies
0.746 0.254 0.000
M40-M43 Deforming dorsopathies
0.746 0.254 0.000
Z53.8 Procedure not carried out for other reasons
0.745 0.255 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.744 0.256 0.000
S89 Other and unspecified injuries of lower leg
0.744 0.256 0.000
Z94 Transplanted organ and tissue status
0.743 0.257 0.000
F31.9 Bipolar affective disorder, unspecified
0.743 0.257 0.000
K07 Dentofacial anomalies [including malocclusion]
0.742 0.258 0.000
K25.4 Chronic or unspecified with haemorrhage
0.742 0.258 0.000
C60-C63 Malignant neoplasms of male genital organs
0.740 0.260 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.738 0.262 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.737 0.263 0.000
M54.56 Low back pain (Lumbar region)
0.737 0.263 0.000
Z41 Procedures for purposes other than remedying health state
0.736 0.264 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.735 0.265 0.000
S20-S29 Injuries to the thorax
0.734 0.266 0.000
J46 Status asthmaticus
0.733 0.267 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.733 0.267 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.733 0.267 0.000
M54.3 Sciatica
0.732 0.268 0.000
W20-W49 Exposure to inanimate mechanical forces
0.732 0.268 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.731 0.269 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.729 0.271 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.729 0.271 0.000
K21 Gastro-oesophageal reflux disease
0.728 0.272 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.727 0.272 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
D00-D09 In situ neoplasms
0.727 0.273 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.726 0.274 0.000
J18.9 Pneumonia, unspecified
0.726 0.274 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.725 0.275 0.000
S80 Superficial injury of lower leg
0.725 0.275 0.000
Z48 Other surgical follow-up care
0.724 0.276 0.000
J02 Acute pharyngitis
0.724 0.276 0.000
C01 Malignant neoplasm of base of tongue
0.724 0.276 0.000
Chapter VII Diseases of the eye and adnexa
0.723 0.277 0.000
M54.1 Radiculopathy
0.722 0.278 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.722 0.278 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.721 0.279 0.000
G90-G99 Other disorders of the nervous system
0.721 0.279 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.721 0.279 0.000
K51 Ulcerative colitis
0.720 0.280 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.720 0.280 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.719 0.281 0.000
M10.99 Gout, unspecified (Site unspecified)
0.719 0.281 0.000
K25.7 Chronic without haemorrhage or perforation
0.719 0.281 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.719 0.281 0.000
N10-N16 Renal tubulo-interstitial diseases
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K11 Diseases of salivary glands
0.717 0.283 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.716 0.284 0.000
Z43 Attention to artificial openings
0.716 0.284 0.000
T66-T78 Other and unspecified effects of external causes
0.715 0.285 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.714 0.286 0.000
C34.0 Main bronchus
0.713 0.286 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.713 0.287 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.713 0.287 0.000
J41 Simple and mucopurulent chronic bronchitis
0.712 0.287 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
M12 Other specific arthropathies
0.712 0.288 0.000
M11 Other crystal arthropathies
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
M07 Psoriatic and enteropathic arthropathies
0.712 0.288 0.000
M05 Seropositive rheumatoid arthritis
0.712 0.288 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.712 0.288 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.711 0.288 0.000
M46 Other inflammatory spondylopathies
0.711 0.289 0.000
M49 Spondylopathies in diseases classified elsewhere
0.711 0.289 0.000
M45 Ankylosing spondylitis
0.711 0.289 0.000
J93.9 Pneumothorax, unspecified
0.710 0.290 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.710 0.290 0.000
E78.5 Hyperlipidaemia, unspecified
0.709 0.291 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.708 0.292 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.707 0.293 0.000
M47.1 Other spondylosis with myelopathy
0.707 0.293 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.707 0.293 0.000
C79 Secondary malignant neoplasm of other sites
0.707 0.293 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.706 0.294 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.706 0.294 0.000
J03 Acute tonsillitis
0.706 0.294 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.705 0.294 0.000
M50.2 Other cervical disk displacement
0.705 0.295 0.000
M54.8 Other dorsalgia
0.705 0.295 0.000
M54.6 Pain in thoracic spine
0.705 0.295 0.000
M54.4 Lumbago with sciatica
0.705 0.295 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.705 0.295 0.000
Z03.3 Observation for suspected nervous system disorder
0.704 0.296 0.000
F99-F99 Unspecified mental disorder
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
F80-F89 Disorders of psychological development
0.704 0.296 0.000
F70-F79 Mental retardation
0.704 0.296 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.296 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.703 0.297 0.000
R47-R49 Symptoms and signs involving speech and voice
0.702 0.298 0.000
Z93.2 Ileostomy status
0.702 0.298 0.000
K90 Intestinal malabsorption
0.700 0.300 0.000
F43 Reaction to severe stress, and adjustment disorders
0.700 0.300 0.000
J94 Other pleural conditions
0.699 0.301 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.699 0.301 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.697 0.303 0.000
T86 Failure and rejection of transplanted organs and tissues
0.697 0.303 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.697 0.303 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.696 0.303 0.000
J96 Respiratory failure, not elsewhere classified
0.696 0.303 0.000
M51.3 Other specified intervertebral disk degeneration
0.696 0.304 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.696 0.304 0.000
M51.9 Intervertebral disk disorder, unspecified
0.696 0.304 0.000
M51.8 Other specified intervertebral disk disorders
0.696 0.304 0.000
M51.4 Schmorl's nodes
0.696 0.304 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.696 0.304 0.000
M13.98 Arthritis, unspecified (Other)
0.696 0.304 0.000
C25 Malignant neoplasm of pancreas
0.695 0.305 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.695 0.305 0.000
C73 Malignant neoplasm of thyroid gland
0.695 0.305 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.694 0.306 0.000
Z99.1 Dependence on respirator
0.694 0.306 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.694 0.306 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.693 0.307 0.000
M13.8 Other specified arthritis
0.693 0.307 0.000
M13.1 Monoarthritis, not elsewhere classified
0.693 0.307 0.000
Chapter VIII Diseases of the ear and mastoid process
0.692 0.308 0.000
M54.55 Low back pain (Thoracolumbar region)
0.692 0.308 0.000
M54.54 Low back pain-Thoracic
0.692 0.308 0.000
M54.53 Low back pain-Cervicothoracic
0.692 0.308 0.000
M54.52 Low back pain-Cervical
0.692 0.308 0.000
M54.51 Low back pain-Occipit-atl-axl
0.692 0.308 0.000
M54.50 Low back pain (Multiple sites in spine)
0.692 0.308 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.692 0.308 0.000
C34.9 Bronchus or lung, unspecified
0.691 0.309 0.000
D64.8 Other specified anaemias
0.690 0.309 0.000
D64.4 Congenital dyserythropoietic anaemia
0.690 0.309 0.000
D64.3 Other sideroblastic anaemias
0.690 0.309 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.690 0.309 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.690 0.309 0.000
D64.0 Hereditary sideroblastic anaemia
0.690 0.309 0.000
M47.89 Other spondylosis (Site unspecified)
0.689 0.310 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.689 0.310 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.689 0.310 0.000
M47.84 Other spondylosis (Thoracic region)
0.689 0.310 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.689 0.310 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.689 0.310 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.690 0.310 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.689 0.311 0.000
K22.8 Other specified diseases of oesophagus
0.689 0.311 0.000
M16.1 Other primary coxarthrosis
0.688 0.312 0.000
M18 Arthrosis of first carpometacarpal joint
0.688 0.312 0.000
K22.9 Disease of oesophagus, unspecified
0.688 0.312 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.687 0.313 0.000
Z80 Family history of malignant neoplasm
0.686 0.314 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.685 0.315 0.000
M54.2 Cervicalgia
0.685 0.315 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.685 0.315 0.000
K92.9 Disease of digestive system, unspecified
0.685 0.315 0.000
K92.8 Other specified diseases of digestive system
0.685 0.315 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.685 0.315 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.684 0.316 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.684 0.316 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.684 0.316 0.000
K27 Peptic ulcer, site unspecified
0.683 0.317 0.000
V10-V19 Pedal cyclist injured in transport accident
0.682 0.318 0.000
J00 Acute nasopharyngitis [common cold]
0.682 0.318 0.000
J60-J70 Lung diseases due to external agents
0.682 0.318 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.681 0.319 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.681 0.319 0.000
Z99.8 Dependence on other enabling machines and devices
0.681 0.319 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.678 0.322 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.678 0.322 0.000
K52.1 Toxic gastro-enteritis and colitis
0.677 0.322 0.000
S40-S49 Injuries to the shoulder and upper arm
0.677 0.323 0.000
Z04 Examination and observation for other reasons
0.677 0.323 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.677 0.323 0.000
K28 Gastrojejunal ulcer
0.677 0.323 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.677 0.323 0.000
N40-N51 Diseases of male genital organs
0.677 0.323 0.000
Z96 Presence of other functional implants
0.676 0.324 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.676 0.324 0.000
M19.0 Primary arthrosis of other joints
0.676 0.324 0.000
N25-N29 Other disorders of kidney and ureter
0.676 0.324 0.000
N60-N64 Disorders of breast
0.675 0.325 0.000
Z01.8 Other specified special examinations
0.674 0.326 0.000
J98.9 Respiratory disorder, unspecified
0.674 0.326 0.000
J98.8 Other specified respiratory disorders
0.674 0.326 0.000
J98.6 Disorders of diaphragm
0.674 0.326 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.674 0.326 0.000
J98.3 Compensatory emphysema
0.674 0.326 0.000
J98.2 Interstitial emphysema
0.674 0.326 0.000
S60-S69 Injuries to the wrist and hand
0.674 0.326 0.000
Z40 Prophylactic surgery
0.674 0.326 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.674 0.326 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.674 0.326 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.674 0.326 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.674 0.326 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.674 0.326 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.674 0.326 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.674 0.326 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.674 0.326 0.000
T36 Poisoning by systemic antibiotics
0.674 0.326 0.000
C09 Malignant neoplasm of tonsil
0.674 0.326 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.673 0.327 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.672 0.327 0.000
K10 Other diseases of jaws
0.672 0.328 0.000
K09 Cysts of oral region, not elsewhere classified
0.672 0.328 0.000
K03 Other diseases of hard tissues of teeth
0.672 0.328 0.000
K00 Disorders of tooth development and eruption
0.672 0.328 0.000
M48 Other spondylopathies
0.672 0.328 0.000
Z54 Convalescence
0.671 0.329 0.000
Z52 Donors of organs and tissues
0.671 0.329 0.000
Z49 Care involving dialysis
0.671 0.329 0.000
Z44 Fitting and adjustment of external prosthetic device
0.671 0.329 0.000
K59 Other functional intestinal disorders
0.671 0.329 0.000
R00 Abnormalities of heart beat
0.669 0.331 0.000
Z02 Examination and encounter for administrative purposes
0.669 0.331 0.000
J17 Pneumonia in diseases classified elsewhere
0.669 0.331 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.669 0.331 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.669 0.331 0.000
J12 Viral pneumonia, not elsewhere classified
0.669 0.331 0.000
J11 Influenza, virus not identified
0.669 0.331 0.000
J10 Influenza due to identified influenza virus
0.669 0.331 0.000
J14 Pneumonia due to Haemophilus influenzae
0.669 0.331 0.000
J09 Influenza due to certain identified influenza virus
0.669 0.331 0.000
S72 Fracture of femur
0.669 0.331 0.000
K12.1 Other forms of stomatitis
0.668 0.332 0.000
Z89 Acquired absence of limb
0.668 0.332 0.000
Z84 Family history of other conditions
0.668 0.332 0.000
Z81 Family history of mental and behavioural disorders
0.668 0.332 0.000
Z10 Routine general health check-up of defined subpopulation
0.668 0.332 0.000
K65 Peritonitis
0.667 0.333 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.667 0.333 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.667 0.333 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.667 0.333 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.667 0.333 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.667 0.333 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.667 0.333 0.000
M13.93 Arthritis, unspecified (Forearm)
0.667 0.333 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.667 0.333 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.667 0.333 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.665 0.335 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.665 0.335 0.000
Y35-Y36 Legal intervention and operations of war
0.665 0.335 0.000
Y10-Y34 Event of undetermined intent
0.665 0.335 0.000
Y00-Y09 Assault
0.665 0.335 0.000
X85-X99 Assault
0.665 0.335 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.665 0.335 0.000
X50-X57 Overexertion, travel and privation
0.665 0.335 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.665 0.335 0.000
X30-X39 Exposure to forces of nature
0.665 0.335 0.000
X20-X29 Contact with venomous animals and plants
0.665 0.335 0.000
X10-X19 Contact with heat and hot substances
0.665 0.335 0.000
X00-X09 Exposure to smoke, fire and flames
0.665 0.335 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.665 0.335 0.000
W75-W84 Other accidental threats to breathing
0.665 0.335 0.000
W65-W74 Accidental drowning and submersion
0.665 0.335 0.000
W50-W64 Exposure to animate mechanical forces
0.665 0.335 0.000
V98-V99 Other and unspecified transport accidents
0.665 0.335 0.000
V95-V97 Air and space transport accidents
0.665 0.335 0.000
V90-V94 Water transport accidents
0.665 0.335 0.000
V80-V89 Other land transport accidents
0.665 0.335 0.000
V70-V79 Bus occupant injured in transport accident
0.665 0.335 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.665 0.335 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.665 0.335 0.000
V40-V49 Car occupant injured in transport accident
0.665 0.335 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.665 0.335 0.000
V01-V09 Pedestrian injured in transport accident
0.665 0.335 0.000
Y95 Nosocomial condition
0.663 0.337 0.000
J95.8 Other postprocedural respiratory disorders
0.663 0.337 0.000
S88 Traumatic amputation of lower leg
0.662 0.338 0.000
S87 Crushing injury of lower leg
0.662 0.338 0.000
S86 Injury of muscle and tendon at lower leg level
0.662 0.338 0.000
S85 Injury of blood vessels at lower leg level
0.662 0.338 0.000
S84 Injury of nerves at lower leg level
0.662 0.338 0.000
R26.3 Immobility
0.661 0.339 0.000
F42 Obsessive-compulsive disorder
0.660 0.340 0.000
M06.0 Seronegative rheumatoid arthritis
0.660 0.340 0.000
Z50.5 Speech therapy
0.660 0.340 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.660 0.340 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.659 0.341 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.659 0.341 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.659 0.341 0.000
S50 Superficial injury of forearm
0.659 0.341 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.658 0.342 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.658 0.342 0.000
Z97 Presence of other devices
0.657 0.343 0.000
Z98 Other postsurgical states
0.657 0.343 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.656 0.344 0.000
J86 Pyothorax
0.656 0.344 0.000
S82 Fracture of lower leg, including ankle
0.656 0.344 0.000
Z82.3 Family history of stroke
0.655 0.344 0.000
C34.3 Lower lobe, bronchus or lung
0.655 0.345 0.000
R06 Abnormalities of breathing
0.655 0.345 0.000
N00-N08 Glomerular diseases
0.654 0.346 0.000
F17.2 Dependence syndrome
0.654 0.346 0.000
M16.0 Primary coxarthrosis, bilateral
0.654 0.346 0.000
X60-X84 Intentional self-harm
0.654 0.346 0.000
M15 Polyarthrosis
0.653 0.347 0.000
K26 Duodenal ulcer
0.652 0.348 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.652 0.348 0.000
K50.8 Other Crohn's disease
0.652 0.348 0.000
K50.0 Crohn's disease of small intestine
0.652 0.348 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.651 0.348 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.651 0.349 0.000
F38 Other mood [affective] disorders
0.651 0.349 0.000
F34 Persistent mood [affective] disorders
0.651 0.349 0.000
F30 Manic episode
0.651 0.349 0.000
F39 Unspecified mood [affective] disorder
0.651 0.349 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.651 0.349 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.651 0.349 0.000
Z03.0 Observation for suspected tuberculosis
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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