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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72799335
log Bayes Factor = 16.5637
Chromosome 5   position 107,878,176  (GRCh37) Explore rs72799335 on Ensembl!
Variant rs72799335 is part of Cluster X0142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
J90-J94 Other diseases of pleura
0.995 0.005 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.994 0.006 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
I35 Nonrheumatic aortic valve disorders
0.992 0.008 0.000
J40-J47 Chronic lower respiratory diseases
0.991 0.009 0.000
I95 Hypotension
0.990 0.010 0.000
J44 Other chronic obstructive pulmonary disease
0.990 0.010 0.000
I95.9 Hypotension, unspecified
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
J90 Pleural effusion, not elsewhere classified
0.980 0.020 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.980 0.020 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.970 0.030 0.000
Y43 Primarily systemic agents
0.969 0.031 0.000
Y95 Nosocomial condition
0.966 0.034 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.962 0.038 0.000
J09-J18 Influenza and pneumonia
0.959 0.041 0.000
I35.0 Aortic (valve) stenosis
0.958 0.042 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.956 0.044 0.000
Y43.3 Other antineoplastic drugs
0.952 0.048 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.952 0.048 0.000
I51 Complications and ill-defined descriptions of heart disease
0.951 0.049 0.000
J93 Pneumothorax
0.948 0.052 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.946 0.054 0.000
M15-M19 Arthrosis
0.945 0.055 0.000
I45 Other conduction disorders
0.942 0.058 0.000
A00-A09 Intestinal infectious diseases
0.941 0.059 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.941 0.059 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.939 0.061 0.000
E20-E35 Disorders of other endocrine glands
0.936 0.064 0.000
I42 Cardiomyopathy
0.918 0.082 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.916 0.084 0.000
S90-S99 Injuries to the ankle and foot
0.916 0.084 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.911 0.089 0.000
M20-M25 Other joint disorders
0.908 0.092 0.000
A30-A49 Other bacterial diseases
0.904 0.096 0.000
W00-W19 Falls
0.901 0.099 0.000
I51.7 Cardiomegaly
0.900 0.100 0.000
I35.1 Aortic (valve) insufficiency
0.898 0.102 0.000
J93.9 Pneumothorax, unspecified
0.898 0.102 0.000
M19 Other arthrosis
0.894 0.106 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.892 0.108 0.000
M17 Gonarthrosis [arthrosis of knee]
0.890 0.110 0.000
J18 Pneumonia, organism unspecified
0.890 0.110 0.000
F41 Other anxiety disorders
0.887 0.113 0.000
M80-M85 Disorders of bone density and structure
0.884 0.116 0.000
B35-B49 Mycoses
0.883 0.117 0.000
G90-G99 Other disorders of the nervous system
0.883 0.117 0.000
I45.1 Other and unspecified right bundle-branch block
0.882 0.118 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.879 0.121 0.000
I46 Cardiac arrest
0.879 0.121 0.000
E70-E90 Metabolic disorders
0.877 0.123 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.876 0.124 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.873 0.127 0.000
A04 Other bacterial intestinal infections
0.873 0.127 0.000
F30-F39 Mood [affective] disorders
0.872 0.128 0.000
F45 Somatoform disorders
0.872 0.128 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.869 0.131 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.869 0.131 0.000
I49 Other cardiac arrhythmias
0.865 0.135 0.000
V10-V19 Pedal cyclist injured in transport accident
0.863 0.137 0.000
I47 Paroxysmal tachycardia
0.860 0.140 0.000
Chapter VIII Diseases of the ear and mastoid process
0.856 0.144 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.855 0.145 0.000
S70-S79 Injuries to the hip and thigh
0.853 0.147 0.000
Y57 Other and unspecified drugs and medicaments
0.852 0.148 0.000
M17.0 Primary gonarthrosis, bilateral
0.852 0.148 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.849 0.151 0.000
M05-M14 Inflammatory polyarthropathies
0.849 0.151 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.848 0.152 0.000
R50-R69 General symptoms and signs
0.846 0.154 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.845 0.155 0.000
E50-E64 Other nutritional deficiencies
0.844 0.156 0.000
M22 Disorders of patella
0.839 0.161 0.000
E87.6 Hypokalaemia
0.839 0.161 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.838 0.162 0.000
G30-G32 Other degenerative diseases of the nervous system
0.838 0.162 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.834 0.165 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.832 0.168 0.000
T82.1 Mechanical complication of cardiac electronic device
0.832 0.168 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.832 0.168 0.000
I38 Endocarditis, valve unspecified
0.829 0.171 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.827 0.173 0.000
I42.9 Cardiomyopathy, unspecified
0.826 0.174 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.824 0.176 0.000
J18.9 Pneumonia, unspecified
0.824 0.176 0.000
M24 Other specific joint derangements
0.823 0.177 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.821 0.179 0.000
B25-B34 Other viral diseases
0.820 0.180 0.000
R26 Abnormalities of gait and mobility
0.820 0.180 0.000
E29 Testicular dysfunction
0.820 0.180 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.820 0.180 0.000
Y44 Agents primarily affecting blood constituents
0.819 0.181 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.815 0.185 0.000
I35.9 Aortic valve disorder, unspecified
0.815 0.185 0.000
G20-G26 Extrapyramidal and movement disorders
0.814 0.186 0.000
H65-H75 Diseases of middle ear and mastoid
0.812 0.188 0.000
R54 Senility
0.811 0.189 0.000
S00-S09 Injuries to the head
0.811 0.189 0.000
F31 Bipolar affective disorder
0.807 0.193 0.000
J94 Other pleural conditions
0.807 0.193 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.806 0.193 0.000
F10.1 Harmful use
0.806 0.194 0.000
R55 Syncope and collapse
0.806 0.194 0.000
J95-J99 Other diseases of the respiratory system
0.805 0.195 0.000
I51.9 Heart disease, unspecified
0.803 0.197 0.000
E16 Other disorders of pancreatic internal secretion
0.802 0.197 0.000
F45.8 Other somatoform disorders
0.801 0.199 0.000
M19.0 Primary arthrosis of other joints
0.801 0.199 0.000
I95.8 Other hypotension
0.800 0.200 0.000
S20-S29 Injuries to the thorax
0.799 0.201 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.797 0.203 0.000
M19.9 Arthrosis, unspecified
0.796 0.204 0.000
X60-X84 Intentional self-harm
0.794 0.206 0.000
F42 Obsessive-compulsive disorder
0.794 0.206 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.793 0.207 0.000
M06 Other rheumatoid arthritis
0.793 0.207 0.000
I49.5 Sick sinus syndrome
0.789 0.211 0.000
A41 Other septicaemia
0.787 0.213 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.787 0.213 0.000
A04.8 Other specified bacterial intestinal infections
0.787 0.213 0.000
V40-V49 Car occupant injured in transport accident
0.787 0.213 0.000
B65-B83 Helminthiases
0.786 0.214 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.786 0.214 0.000
M40-M43 Deforming dorsopathies
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.785 0.215 0.000
T90 Sequelae of injuries of head
0.782 0.218 0.000
I47.2 Ventricular tachycardia
0.782 0.218 0.000
I46.9 Cardiac arrest, unspecified
0.780 0.220 0.000
M17.1 Other primary gonarthrosis
0.779 0.221 0.000
X50-X57 Overexertion, travel and privation
0.779 0.221 0.000
H66 Suppurative and unspecified otitis media
0.779 0.221 0.000
S70 Superficial injury of hip and thigh
0.778 0.222 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.776 0.224 0.000
B35 Dermatophytosis
0.775 0.225 0.000
J40 Bronchitis, not specified as acute or chronic
0.773 0.227 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.772 0.227 0.000
S50-S59 Injuries to the elbow and forearm
0.772 0.228 0.000
E61 Deficiency of other nutrient elements
0.772 0.228 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.772 0.228 0.000
J93.1 Other spontaneous pneumothorax
0.771 0.229 0.000
R56 Convulsions, not elsewhere classified
0.771 0.229 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.771 0.229 0.000
R25 Abnormal involuntary movements
0.770 0.230 0.000
T79-T79 Certain early complications of trauma
0.768 0.232 0.000
G70-G73 Diseases of myoneural junction and muscle
0.767 0.233 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.765 0.235 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.765 0.235 0.000
T91 Sequelae of injuries of neck and trunk
0.765 0.235 0.000
I45.5 Other specified heart block
0.764 0.236 0.000
M19.94 Arthrosis, unspecified (Hand)
0.763 0.237 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.763 0.237 0.000
M21 Other acquired deformities of limbs
0.763 0.237 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.762 0.238 0.000
G95 Other diseases of spinal cord
0.761 0.238 0.000
S90 Superficial injury of ankle and foot
0.761 0.239 0.000
Y52 Agents primarily affecting the cardiovascular system
0.761 0.239 0.000
A49 Bacterial infection of unspecified site
0.760 0.240 0.000
M25 Other joint disorders, not elsewhere classified
0.760 0.240 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.760 0.240 0.000
N17.9 Acute renal failure, unspecified
0.759 0.241 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.757 0.242 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.755 0.245 0.000
R53 Malaise and fatigue
0.755 0.245 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.755 0.245 0.000
N17 Acute renal failure
0.755 0.245 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.754 0.246 0.000
F41.1 Generalised anxiety disorder
0.753 0.247 0.000
Chapter XIV Diseases of the genitourinary system
0.753 0.247 0.000
M06.9 Rheumatoid arthritis, unspecified
0.753 0.247 0.000
J18.0 Bronchopneumonia, unspecified
0.752 0.248 0.000
Y57.9 Drug or medicament, unspecified
0.751 0.249 0.000
N17-N19 Renal failure
0.750 0.250 0.000
G40-G47 Episodic and paroxysmal disorders
0.749 0.251 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.749 0.251 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.749 0.251 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.749 0.251 0.000
I42.0 Dilated cardiomyopathy
0.749 0.251 0.000
E16.2 Hypoglycaemia, unspecified
0.747 0.253 0.000
I36 Nonrheumatic tricuspid valve disorders
0.746 0.254 0.000
M81 Osteoporosis without pathological fracture
0.746 0.254 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.743 0.257 0.000
I30 Acute pericarditis
0.743 0.257 0.000
I51.4 Myocarditis, unspecified
0.742 0.258 0.000
W18 Other fall on same level
0.742 0.258 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.742 0.258 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.741 0.259 0.000
E34 Other endocrine disorders
0.740 0.260 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.740 0.260 0.000
Y46.4 Iminostilbenes
0.739 0.261 0.000
G83 Other paralytic syndromes
0.739 0.261 0.000
E29.1 Testicular hypofunction
0.737 0.263 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.737 0.263 0.000
M24.2 Disorder of ligament
0.736 0.264 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.736 0.264 0.000
X20-X29 Contact with venomous animals and plants
0.736 0.264 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.735 0.265 0.000
E40-E46 Malnutrition
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
I95.2 Hypotension due to drugs
0.734 0.266 0.000
S92 Fracture of foot, except ankle
0.733 0.267 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.732 0.268 0.000
E88 Other metabolic disorders
0.731 0.269 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.731 0.269 0.000
G93 Other disorders of brain
0.731 0.269 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.730 0.270 0.000
S40-S49 Injuries to the shoulder and upper arm
0.728 0.272 0.000
Y83.8 Other surgical procedures
0.728 0.272 0.000
M22.4 Chondromalacia patellae
0.727 0.273 0.000
Q23 Congenital malformations of aortic and mitral valves
0.727 0.273 0.000
E87.2 Acidosis
0.726 0.274 0.000
B15-B19 Viral hepatitis
0.726 0.274 0.000
G82 Paraplegia and tetraplegia
0.725 0.275 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.724 0.276 0.000
F33 Recurrent depressive disorder
0.724 0.276 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.724 0.276 0.000
Y40 Systemic antibiotics
0.723 0.277 0.000
S02 Fracture of skull and facial bones
0.722 0.278 0.000
F40 Phobic anxiety disorders
0.721 0.279 0.000
E61.1 Iron deficiency
0.721 0.279 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.720 0.280 0.000
M22.2 Patellofemoral disorders
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
R56.8 Other and unspecified convulsions
0.717 0.283 0.000
F41.9 Anxiety disorder, unspecified
0.716 0.284 0.000
I42.6 Alcoholic cardiomyopathy
0.716 0.284 0.000
Y46.2 Hydantoin derivatives
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
E23 Hypofunction and other disorders of pituitary gland
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
H66.9 Otitis media, unspecified
0.715 0.285 0.000
E21.0 Primary hyperparathyroidism
0.714 0.286 0.000
I45.9 Conduction disorder, unspecified
0.713 0.286 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.712 0.287 0.000
E86 Volume depletion
0.712 0.288 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.712 0.288 0.000
F10.3 Withdrawal state
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.712 0.288 0.000
Y58 Bacterial vaccines
0.712 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.712 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.712 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.712 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.712 0.288 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.712 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.712 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.288 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
I35.8 Other aortic valve disorders
0.711 0.289 0.000
W13 Fall from, out of or through building or structure
0.711 0.289 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.290 0.000
I95.0 Idiopathic hypotension
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
M80 Osteoporosis with pathological fracture
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.708 0.292 0.000
T86 Failure and rejection of transplanted organs and tissues
0.706 0.293 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.707 0.293 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.706 0.294 0.000
J11 Influenza, virus not identified
0.706 0.294 0.000
I49.4 Other and unspecified premature depolarisation
0.706 0.294 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.705 0.295 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
E65-E68 Obesity and other hyperalimentation
0.704 0.296 0.000
T81 Complications of procedures, not elsewhere classified
0.704 0.296 0.000
J14 Pneumonia due to Haemophilus influenzae
0.704 0.296 0.000
I99 Other and unspecified disorders of circulatory system
0.703 0.297 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.702 0.297 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.702 0.297 0.000
Y98 Lifestyle-related condition
0.702 0.297 0.000
Y97 Environmental-pollution-related condition
0.702 0.297 0.000
Y96 Work-related condition
0.702 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
G24 Dystonia
0.702 0.298 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.701 0.299 0.000
B49 Unspecified mycosis
0.700 0.300 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.300 0.000
J10 Influenza due to identified influenza virus
0.698 0.302 0.000
H66.3 Other chronic suppurative otitis media
0.698 0.302 0.000
M17.3 Other posttraumatic gonarthrosis
0.698 0.302 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.697 0.303 0.000
B35.3 Tinea pedis
0.697 0.303 0.000
E10-E14 Diabetes mellitus
0.696 0.304 0.000
F48 Other neurotic disorders
0.696 0.304 0.000
F44 Dissociative [conversion] disorders
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
Y44.2 Anticoagulants
0.695 0.305 0.000
B34 Viral infection of unspecified site
0.695 0.305 0.000
Y43.9 Primarily systemic agent, unspecified
0.695 0.305 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.695 0.305 0.000
Y43.6 Enzymes, not elsewhere classified
0.695 0.305 0.000
Y43.5 Acidifying and alkalising agents
0.695 0.305 0.000
Y43.2 Antineoplastic natural products
0.695 0.305 0.000
Y43.1 Antineoplastic antimetabolites
0.695 0.305 0.000
Y43.0 Antiallergic and antiemetic drugs
0.695 0.305 0.000
G40 Epilepsy
0.693 0.307 0.000
R25.2 Cramp and spasm
0.693 0.307 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.692 0.308 0.000
I33 Acute and subacute endocarditis
0.691 0.308 0.000
M00-M03 Infectious arthropathies
0.691 0.309 0.000
V18.0 Driver injured in nontraffic accident
0.689 0.311 0.000
I34 Nonrheumatic mitral valve disorders
0.689 0.311 0.000
J17 Pneumonia in diseases classified elsewhere
0.688 0.312 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.688 0.312 0.000
J12 Viral pneumonia, not elsewhere classified
0.688 0.312 0.000
J09 Influenza due to certain identified influenza virus
0.688 0.312 0.000
M05 Seropositive rheumatoid arthritis
0.687 0.313 0.000
A02 Other Salmonella infections
0.686 0.314 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.686 0.314 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.686 0.314 0.000
E21.3 Hyperparathyroidism, unspecified
0.685 0.315 0.000
T92 Sequelae of injuries of upper limb
0.685 0.315 0.000
Y43.4 Immunosuppressive agents
0.685 0.315 0.000
F10.2 Dependence syndrome
0.685 0.315 0.000
M84 Disorders of continuity of bone
0.682 0.317 0.000
W19 Unspecified fall
0.682 0.318 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.682 0.318 0.000
I51.6 Cardiovascular disease, unspecified
0.682 0.318 0.000
I51.5 Myocardial degeneration
0.682 0.318 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.682 0.318 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.682 0.318 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.682 0.318 0.000
I51.0 Cardiac septal defect, acquired
0.682 0.318 0.000
M91-M94 Chondropathies
0.682 0.318 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.681 0.319 0.000
S91 Open wound of ankle and foot
0.681 0.319 0.000
B44 Aspergillosis
0.680 0.320 0.000
J93.8 Other pneumothorax
0.680 0.320 0.000
J93.0 Spontaneous tension pneumothorax
0.680 0.320 0.000
M34 Systemic sclerosis
0.680 0.320 0.000
S20 Superficial injury of thorax
0.680 0.320 0.000
G95.8 Other specified diseases of spinal cord
0.679 0.321 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.679 0.321 0.000
R64 Cachexia
0.679 0.321 0.000
J94.2 Haemothorax
0.679 0.321 0.000
R26.3 Immobility
0.679 0.321 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.678 0.322 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.678 0.322 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.678 0.322 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.678 0.322 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.678 0.322 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.678 0.322 0.000
F11 Mental and behavioural disorders due to use of opioids
0.678 0.322 0.000
I49.0 Ventricular fibrillation and flutter
0.678 0.322 0.000
A41.9 Septicaemia, unspecified
0.678 0.322 0.000
M15 Polyarthrosis
0.677 0.322 0.000
F43 Reaction to severe stress, and adjustment disorders
0.677 0.323 0.000
W20-W49 Exposure to inanimate mechanical forces
0.676 0.324 0.000
I45.8 Other specified conduction disorders
0.676 0.324 0.000
I45.4 Nonspecific intraventricular block
0.676 0.324 0.000
I45.3 Trifascicular block
0.676 0.324 0.000
I45.2 Bifascicular block
0.676 0.324 0.000
I45.0 Right fascicular block
0.676 0.324 0.000
W08 Fall involving other furniture
0.675 0.324 0.000
S60-S69 Injuries to the wrist and hand
0.675 0.325 0.000
A07 Other protozoal intestinal diseases
0.674 0.326 0.000
A06 Amoebiasis
0.674 0.326 0.000
A05 Other bacterial foodborne intoxications
0.674 0.326 0.000
A03 Shigellosis
0.674 0.326 0.000
A01 Typhoid and paratyphoid fevers
0.674 0.326 0.000
A00 Cholera
0.674 0.326 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.674 0.326 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.674 0.326 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.674 0.326 0.000
T82.3 Mechanical complication of other vascular grafts
0.674 0.326 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.674 0.326 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.672 0.328 0.000
T98 Sequelae of other and unspecified effects of external causes
0.672 0.328 0.000
E27 Other disorders of adrenal gland
0.672 0.328 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.672 0.328 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.671 0.329 0.000
E32 Diseases of thymus
0.671 0.329 0.000
E31 Polyglandular dysfunction
0.671 0.329 0.000
E30 Disorders of puberty, not elsewhere classified
0.671 0.329 0.000
E26 Hyperaldosteronism
0.671 0.329 0.000
E25 Adrenogenital disorders
0.671 0.329 0.000
E24 Cushing's syndrome
0.671 0.329 0.000
E20 Hypoparathyroidism
0.671 0.329 0.000
Q80-Q89 Other congenital malformations
0.669 0.331 0.000
M43 Other deforming dorsopathies
0.669 0.331 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.669 0.331 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.668 0.332 0.000
S51 Open wound of forearm
0.666 0.334 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.665 0.335 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.665 0.335 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.665 0.335 0.000
E22 Hyperfunction of pituitary gland
0.664 0.336 0.000
X41.9 Unspecified place
0.664 0.336 0.000
G96 Other disorders of central nervous system
0.663 0.337 0.000
I46.0 Cardiac arrest with successful resuscitation
0.662 0.337 0.000
F17.1 Harmful use
0.662 0.338 0.000
S99 Other and unspecified injuries of ankle and foot
0.662 0.338 0.000
F80-F89 Disorders of psychological development
0.661 0.339 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.661 0.339 0.000
M85 Other disorders of bone density and structure
0.659 0.341 0.000
I42.8 Other cardiomyopathies
0.658 0.342 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.658 0.342 0.000
I42.5 Other restrictive cardiomyopathy
0.658 0.342 0.000
I42.4 Endocardial fibroelastosis
0.658 0.342 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.658 0.342 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.658 0.342 0.000
Q23.1 Congenital insufficiency of aortic valve
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
M21.0 Valgus deformity, not elsewhere classified
0.657 0.343 0.000
S98 Traumatic amputation of ankle and foot
0.656 0.343 0.000
S97 Crushing injury of ankle and foot
0.656 0.343 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.656 0.343 0.000
S95 Injury of blood vessels at ankle and foot level
0.656 0.343 0.000
S94 Injury of nerves at ankle and foot level
0.656 0.343 0.000
Q21 Congenital malformations of cardiac septa
0.656 0.344 0.000
I49.1 Atrial premature depolarisation
0.656 0.344 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.656 0.344 0.000
J43 Emphysema
0.656 0.344 0.000
G83.4 Cauda equina syndrome
0.656 0.344 0.000
A46 Erysipelas
0.655 0.344 0.000
E10 Insulin-dependent diabetes mellitus
0.654 0.345 0.000
T95 Sequelae of burns, corrosions and frostbite
0.653 0.347 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.653 0.347 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.653 0.347 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.653 0.347 0.000
J91 Pleural effusion in conditions classified elsewhere
0.652 0.347 0.000
I47.0 Reentry ventricular arrhythmia
0.651 0.349 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.651 0.349 0.000
M33 Dermatopolymyositis
0.651 0.349 0.000
M32 Systemic lupus erythematosus
0.651 0.349 0.000
M30 Polyarteritis nodosa and related conditions
0.651 0.349 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.651 0.349 0.000
N25-N29 Other disorders of kidney and ureter
0.649 0.351 0.000
A48 Other bacterial diseases, not elsewhere classified
0.648 0.352 0.000
A44 Bartonellosis
0.648 0.352 0.000
A43 Nocardiosis
0.648 0.352 0.000
A42 Actinomycosis
0.648 0.352 0.000
A40 Streptococcal septicaemia
0.648 0.352 0.000
A39 Meningococcal infection
0.648 0.352 0.000
A37 Whooping cough
0.648 0.352 0.000
A36 Diphtheria
0.648 0.352 0.000
A32 Listeriosis
0.648 0.352 0.000
A31 Infection due to other mycobacteria
0.648 0.352 0.000
A30 Leprosy [Hansen's disease]
0.648 0.352 0.000
A38 Scarlet fever
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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