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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72821574
log Bayes Factor = 15.3356
Chromosome 6   position 10,709,632  (GRCh37) Explore rs72821574 on Ensembl!
Variant rs72821574 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.996 0.004 0.000
I20-I25 Ischaemic heart diseases
0.994 0.006 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
I20 Angina pectoris
0.991 0.009 0.000
E11.9 Without complications
0.983 0.017 0.000
I20.0 Unstable angina
0.981 0.019 0.000
Chapter VII Diseases of the eye and adnexa
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.970 0.030 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.969 0.031 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
E70-E90 Metabolic disorders
0.967 0.033 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.957 0.043 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.955 0.045 0.000
N17-N19 Renal failure
0.949 0.051 0.000
Chapter V Mental and behavioural disorders
0.945 0.055 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.938 0.062 0.000
R50-R69 General symptoms and signs
0.938 0.062 0.000
Chapter X Diseases of the respiratory system
0.932 0.068 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.930 0.070 0.000
I20.9 Angina pectoris, unspecified
0.929 0.071 0.000
M70-M79 Other soft tissue disorders
0.926 0.074 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.926 0.074 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.923 0.077 0.000
E78.0 Pure hypercholesterolaemia
0.922 0.078 0.000
D10-D36 Benign neoplasms
0.921 0.079 0.000
Chapter XXI Factors influencing health status and contact with health services
0.919 0.081 0.000
N00-N08 Glomerular diseases
0.916 0.084 0.000
R51 Headache
0.916 0.084 0.000
H40-H42 Glaucoma
0.915 0.085 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.914 0.086 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.911 0.089 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.911 0.089 0.000
C15-C26 Malignant neoplasms of digestive organs
0.907 0.093 0.000
M45-M49 Spondylopathies
0.907 0.093 0.000
L90 Atrophic disorders of skin
0.901 0.099 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.899 0.101 0.000
I10-I15 Hypertensive diseases
0.898 0.102 0.000
I30-I52 Other forms of heart disease
0.892 0.108 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.892 0.108 0.000
Z51 Other medical care
0.891 0.109 0.000
M75 Shoulder lesions
0.889 0.111 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.886 0.114 0.000
Z51.0 Radiotherapy session
0.885 0.115 0.000
E00-E07 Disorders of thyroid gland
0.881 0.119 0.000
N20-N23 Urolithiasis
0.876 0.124 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.876 0.124 0.000
H40 Glaucoma
0.875 0.125 0.000
R20 Disturbances of skin sensation
0.873 0.127 0.000
N17 Acute renal failure
0.870 0.130 0.000
I24 Other acute ischaemic heart diseases
0.869 0.131 0.000
D00-D09 In situ neoplasms
0.868 0.132 0.000
M75.1 Rotator cuff syndrome
0.868 0.132 0.000
D12.6 Colon, unspecified
0.865 0.135 0.000
J20-J22 Other acute lower respiratory infections
0.861 0.139 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.856 0.144 0.000
C51-C58 Malignant neoplasms of female genital organs
0.856 0.144 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.856 0.144 0.000
O60-O75 Complications of labour and delivery
0.855 0.145 0.000
L89 Decubitus ulcer
0.855 0.145 0.000
G40-G47 Episodic and paroxysmal disorders
0.854 0.146 0.000
N40-N51 Diseases of male genital organs
0.852 0.148 0.000
L90.5 Scar conditions and fibrosis of skin
0.851 0.149 0.000
N18 Chronic renal failure
0.850 0.150 0.000
R94 Abnormal results of function studies
0.850 0.150 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.849 0.151 0.000
N10-N16 Renal tubulo-interstitial diseases
0.849 0.151 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.848 0.152 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.847 0.153 0.000
C64-C68 Malignant neoplasms of urinary tract
0.840 0.160 0.000
N23 Unspecified renal colic
0.839 0.161 0.000
J40-J47 Chronic lower respiratory diseases
0.834 0.166 0.000
H25-H28 Disorders of lens
0.834 0.166 0.000
E11.5 With peripheral circulatory complications
0.831 0.169 0.000
G90-G99 Other disorders of the nervous system
0.828 0.172 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.820 0.180 0.000
D12.3 Transverse colon
0.819 0.181 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.816 0.184 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.814 0.186 0.000
N17.9 Acute renal failure, unspecified
0.814 0.186 0.000
R61 Hyperhidrosis
0.812 0.188 0.000
C78.7 Secondary malignant neoplasm of liver
0.812 0.188 0.000
I46 Cardiac arrest
0.812 0.188 0.000
J22 Unspecified acute lower respiratory infection
0.810 0.190 0.000
I35 Nonrheumatic aortic valve disorders
0.809 0.191 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.806 0.194 0.000
M47 Spondylosis
0.805 0.195 0.000
G20-G26 Extrapyramidal and movement disorders
0.803 0.197 0.000
H40.0 Glaucoma suspect
0.802 0.198 0.000
H43-H45 Disorders of vitreous body and globe
0.801 0.199 0.000
L91 Hypertrophic disorders of skin
0.799 0.201 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.795 0.205 0.000
C50-C50 Malignant neoplasm of breast
0.794 0.206 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.793 0.207 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.793 0.207 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.792 0.208 0.000
E11.3 With ophthalmic complications
0.792 0.208 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.792 0.208 0.000
E11.4 With neurological complications
0.791 0.209 0.000
I10 Essential (primary) hypertension
0.791 0.209 0.000
N03 Chronic nephritic syndrome
0.790 0.210 0.000
D12.8 Rectum
0.790 0.210 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.789 0.211 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.787 0.213 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.786 0.214 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.785 0.215 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.780 0.220 0.000
Z51.2 Other chemotherapy
0.779 0.221 0.000
E86 Volume depletion
0.778 0.222 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.777 0.223 0.000
M40-M43 Deforming dorsopathies
0.777 0.223 0.000
E83 Disorders of mineral metabolism
0.777 0.223 0.000
D05 Carcinoma in situ of breast
0.776 0.224 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.774 0.226 0.000
S70-S79 Injuries to the hip and thigh
0.773 0.227 0.000
I22 Subsequent myocardial infarction
0.772 0.228 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.771 0.229 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.771 0.229 0.000
E10 Insulin-dependent diabetes mellitus
0.769 0.231 0.000
M80-M85 Disorders of bone density and structure
0.769 0.231 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.768 0.232 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.768 0.232 0.000
F99-F99 Unspecified mental disorder
0.768 0.232 0.000
D23 Other benign neoplasms of skin
0.767 0.233 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.765 0.235 0.000
E20-E35 Disorders of other endocrine glands
0.764 0.236 0.000
S80-S89 Injuries to the knee and lower leg
0.764 0.236 0.000
C18 Malignant neoplasm of colon
0.764 0.236 0.000
M05-M14 Inflammatory polyarthropathies
0.763 0.237 0.000
C25 Malignant neoplasm of pancreas
0.761 0.239 0.000
N60-N64 Disorders of breast
0.761 0.239 0.000
R05 Cough
0.757 0.243 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.756 0.244 0.000
L89.1 Stage II decubitus ulcer
0.756 0.244 0.000
N99-N99 Other disorders of the genitourinary system
0.755 0.245 0.000
R20.2 Paraesthesia of skin
0.754 0.246 0.000
R21 Rash and other nonspecific skin eruption
0.753 0.247 0.000
C78.0 Secondary malignant neoplasm of lung
0.752 0.248 0.000
Z51.8 Other specified medical care
0.752 0.248 0.000
D12.0 Caecum
0.751 0.249 0.000
N04 Nephrotic syndrome
0.750 0.250 0.000
I35.0 Aortic (valve) stenosis
0.750 0.250 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.749 0.251 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.748 0.251 0.000
R60 Oedema, not elsewhere classified
0.748 0.252 0.000
H25 Senile cataract
0.747 0.253 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.747 0.253 0.000
D34 Benign neoplasm of thyroid gland
0.747 0.253 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.744 0.256 0.000
C67 Malignant neoplasm of bladder
0.743 0.256 0.000
C56 Malignant neoplasm of ovary
0.743 0.257 0.000
J40 Bronchitis, not specified as acute or chronic
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.740 0.260 0.000
N50 Other disorders of male genital organs
0.740 0.260 0.000
L20-L30 Dermatitis and eczema
0.740 0.260 0.000
R47-R49 Symptoms and signs involving speech and voice
0.739 0.261 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.737 0.263 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.737 0.263 0.000
R54 Senility
0.737 0.263 0.000
E14 Unspecified diabetes mellitus
0.735 0.265 0.000
M48 Other spondylopathies
0.734 0.266 0.000
F30-F39 Mood [affective] disorders
0.733 0.267 0.000
H40.1 Primary open-angle glaucoma
0.732 0.268 0.000
R25 Abnormal involuntary movements
0.732 0.268 0.000
I05-I09 Chronic rheumatic heart diseases
0.732 0.268 0.000
G37 Other demyelinating diseases of central nervous system
0.730 0.269 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.729 0.271 0.000
G93 Other disorders of brain
0.729 0.271 0.000
R50 Fever of unknown origin
0.728 0.272 0.000
M71 Other bursopathies
0.727 0.273 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.727 0.273 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.727 0.273 0.000
O80-O84 Delivery
0.726 0.274 0.000
I12 Hypertensive renal disease
0.726 0.274 0.000
N13 Obstructive and reflux uropathy
0.725 0.275 0.000
E05.9 Thyrotoxicosis, unspecified
0.725 0.275 0.000
Z49 Care involving dialysis
0.725 0.275 0.000
J09-J18 Influenza and pneumonia
0.724 0.276 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.722 0.278 0.000
R61.9 Hyperhidrosis, unspecified
0.722 0.278 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.721 0.279 0.000
Z42 Follow-up care involving plastic surgery
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.717 0.283 0.000
N05 Unspecified nephritic syndrome
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
E13 Other specified diabetes mellitus
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
I46.9 Cardiac arrest, unspecified
0.713 0.286 0.000
N43 Hydrocele and spermatocele
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
R26 Abnormalities of gait and mobility
0.713 0.287 0.000
M46 Other inflammatory spondylopathies
0.712 0.288 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.712 0.288 0.000
I34 Nonrheumatic mitral valve disorders
0.712 0.288 0.000
N18.9 Chronic renal failure, unspecified
0.711 0.289 0.000
E11.8 With unspecified complications
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.6 With other specified complications
0.711 0.289 0.000
E11.2 With renal complications
0.711 0.289 0.000
E11.1 With ketoacidosis
0.711 0.289 0.000
E11.0 With coma
0.711 0.289 0.000
R52 Pain, not elsewhere classified
0.711 0.289 0.000
I20.1 Angina pectoris with documented spasm
0.710 0.290 0.000
M86-M90 Other osteopathies
0.710 0.290 0.000
I51 Complications and ill-defined descriptions of heart disease
0.710 0.290 0.000
S60-S69 Injuries to the wrist and hand
0.710 0.290 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.710 0.290 0.000
J47 Bronchiectasis
0.710 0.290 0.000
H40.5 Glaucoma secondary to other eye disorders
0.708 0.292 0.000
D12.7 Rectosigmoid junction
0.707 0.292 0.000
C60-C63 Malignant neoplasms of male genital organs
0.707 0.293 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.706 0.294 0.000
G44 Other headache syndromes
0.704 0.296 0.000
R68 Other general symptoms and signs
0.704 0.296 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.704 0.296 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.704 0.296 0.000
H25.8 Other senile cataract
0.704 0.296 0.000
Z52 Donors of organs and tissues
0.703 0.297 0.000
R94.5 Abnormal results of liver function studies
0.703 0.297 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.702 0.298 0.000
D12.5 Sigmoid colon
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
L90.0 Lichen sclerosus et atrophicus
0.700 0.300 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.700 0.300 0.000
N03.9 Unspecified
0.700 0.300 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.699 0.301 0.000
L50-L54 Urticaria and erythema
0.699 0.301 0.000
E04 Other non-toxic goitre
0.698 0.302 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.698 0.302 0.000
H55-H59 Other disorders of eye and adnexa
0.697 0.303 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.697 0.303 0.000
H10-H13 Disorders of conjunctiva
0.697 0.303 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
G70-G73 Diseases of myoneural junction and muscle
0.695 0.304 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.304 0.000
D50-D53 Nutritional anaemias
0.695 0.305 0.000
O16 Unspecified maternal hypertension
0.695 0.305 0.000
D22 Melanocytic naevi
0.695 0.305 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.694 0.306 0.000
L10-L14 Bullous disorders
0.694 0.306 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.694 0.306 0.000
M91-M94 Chondropathies
0.694 0.306 0.000
M60-M63 Disorders of muscles
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.694 0.306 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.694 0.306 0.000
E85 Amyloidosis
0.693 0.307 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.307 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.307 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.307 0.000
E74 Other disorders of carbohydrate metabolism
0.693 0.307 0.000
E73 Lactose intolerance
0.693 0.307 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.307 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.307 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.307 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.693 0.307 0.000
R02 Gangrene, not elsewhere classified
0.691 0.309 0.000
I27 Other pulmonary heart diseases
0.691 0.309 0.000
M75.4 Impingement syndrome of shoulder
0.691 0.309 0.000
E89.0 Postprocedural hypothyroidism
0.691 0.309 0.000
M45 Ankylosing spondylitis
0.690 0.309 0.000
M77 Other enthesopathies
0.689 0.311 0.000
I20.8 Other forms of angina pectoris
0.687 0.313 0.000
L91.8 Other hypertrophic disorders of skin
0.687 0.313 0.000
O73 Retained placenta and membranes, without haemorrhage
0.686 0.314 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.686 0.314 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.686 0.314 0.000
L94 Other localised connective tissue disorders
0.686 0.314 0.000
L93 Lupus erythematosus
0.686 0.314 0.000
L87 Transepidermal elimination disorders
0.686 0.314 0.000
L88 Pyoderma gangrenosum
0.686 0.314 0.000
L86 Keratoderma in diseases classified elsewhere
0.686 0.314 0.000
L84 Corns and callosities
0.686 0.314 0.000
L83 Acanthosis nigricans
0.686 0.314 0.000
L80 Vitiligo
0.686 0.314 0.000
G60 Hereditary and idiopathic neuropathy
0.686 0.314 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.685 0.315 0.000
J00-J06 Acute upper respiratory infections
0.685 0.315 0.000
O85-O92 Complications predominantly related to the puerperium
0.685 0.315 0.000
S40-S49 Injuries to the shoulder and upper arm
0.685 0.315 0.000
J44 Other chronic obstructive pulmonary disease
0.684 0.316 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.683 0.317 0.000
N02 Recurrent and persistent haematuria
0.683 0.317 0.000
Z51.1 Chemotherapy session for neoplasm
0.683 0.317 0.000
D05.1 Intraductal carcinoma in situ
0.683 0.317 0.000
R94.3 Abnormal results of cardiovascular function studies
0.683 0.317 0.000
D41.0 Kidney
0.681 0.319 0.000
E16 Other disorders of pancreatic internal secretion
0.681 0.319 0.000
G43 Migraine
0.681 0.319 0.000
E88 Other metabolic disorders
0.680 0.320 0.000
G62 Other polyneuropathies
0.680 0.320 0.000
I46.0 Cardiac arrest with successful resuscitation
0.678 0.322 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.678 0.322 0.000
F80-F89 Disorders of psychological development
0.678 0.322 0.000
F70-F79 Mental retardation
0.678 0.322 0.000
F60-F69 Disorders of adult personality and behaviour
0.678 0.322 0.000
T66-T78 Other and unspecified effects of external causes
0.677 0.323 0.000
D60-D64 Aplastic and other anaemias
0.677 0.323 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.675 0.325 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.675 0.325 0.000
G35 Multiple sclerosis
0.673 0.327 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.673 0.327 0.000
E78.8 Other disorders of lipoprotein metabolism
0.673 0.327 0.000
E78.6 Lipoprotein deficiency
0.673 0.327 0.000
E78.4 Other hyperlipidaemia
0.673 0.327 0.000
E78.3 Hyperchylomicronaemia
0.673 0.327 0.000
E78.2 Mixed hyperlipidaemia
0.673 0.327 0.000
E78.1 Pure hyperglyceridaemia
0.673 0.327 0.000
I30 Acute pericarditis
0.673 0.327 0.000
N25-N29 Other disorders of kidney and ureter
0.673 0.327 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.672 0.328 0.000
R62 Lack of expected normal physiological development
0.672 0.328 0.000
R57 Shock, not elsewhere classified
0.672 0.328 0.000
R64 Cachexia
0.672 0.328 0.000
R58 Haemorrhage, not elsewhere classified
0.672 0.328 0.000
F17.1 Harmful use
0.672 0.328 0.000
R27 Other lack of coordination
0.671 0.328 0.000
I60-I69 Cerebrovascular diseases
0.671 0.329 0.000
J86 Pyothorax
0.671 0.329 0.000
Z40 Prophylactic surgery
0.671 0.329 0.000
O48 Prolonged pregnancy
0.670 0.330 0.000
M47.8 Other spondylosis
0.670 0.330 0.000
Z12 Special screening examination for neoplasms
0.670 0.330 0.000
D46 Myelodysplastic syndromes
0.669 0.331 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.668 0.332 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.668 0.332 0.000
C79 Secondary malignant neoplasm of other sites
0.667 0.333 0.000
D10 Benign neoplasm of mouth and pharynx
0.667 0.333 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.667 0.333 0.000
T33-T35 Frostbite
0.667 0.333 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.667 0.333 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.667 0.333 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.667 0.333 0.000
T00-T07 Injuries involving multiple body regions
0.667 0.333 0.000
S10-S19 Injuries to the neck
0.667 0.333 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.666 0.334 0.000
T79-T79 Certain early complications of trauma
0.666 0.334 0.000
C53 Malignant neoplasm of cervix uteri
0.664 0.335 0.000
M76 Enthesopathies of lower limb, excluding foot
0.664 0.336 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.336 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.664 0.336 0.000
R23 Other skin changes
0.664 0.336 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.663 0.337 0.000
D47.1 Chronic myeloproliferative disease
0.663 0.337 0.000
I47 Paroxysmal tachycardia
0.663 0.337 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.662 0.338 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.662 0.338 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.661 0.339 0.000
H43 Disorders of vitreous body
0.661 0.339 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.661 0.339 0.000
I51.7 Cardiomegaly
0.661 0.339 0.000
H40.9 Glaucoma, unspecified
0.660 0.340 0.000
S72 Fracture of femur
0.660 0.340 0.000
D31 Benign neoplasm of eye and adnexa
0.660 0.340 0.000
D30 Benign neoplasm of urinary organs
0.660 0.340 0.000
D29 Benign neoplasm of male genital organs
0.660 0.340 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.660 0.340 0.000
D26 Other benign neoplasms of uterus
0.660 0.340 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.660 0.340 0.000
D19 Benign neoplasm of mesothelial tissue
0.660 0.340 0.000
D16 Benign neoplasm of bone and articular cartilage
0.660 0.340 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.660 0.340 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.660 0.340 0.000
D03 Melanoma in situ
0.660 0.340 0.000
L85 Other epidermal thickening
0.660 0.340 0.000
O66 Other obstructed labour
0.660 0.340 0.000
D11 Benign neoplasm of major salivary glands
0.658 0.342 0.000
N18.5 Chronic kidney disease, stage 5
0.658 0.342 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.657 0.343 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.657 0.343 0.000
N06 Isolated proteinuria with specified morphological lesion
0.657 0.343 0.000
N01 Rapidly progressive nephritic syndrome
0.657 0.343 0.000
N00 Acute nephritic syndrome
0.657 0.343 0.000
N30-N39 Other diseases of urinary system
0.656 0.344 0.000
H42 Glaucoma in diseases classified elsewhere
0.656 0.344 0.000
D12.9 Anus and anal canal
0.656 0.344 0.000
D12.1 Appendix
0.656 0.344 0.000
Z51.5 Palliative care
0.655 0.345 0.000
E65-E68 Obesity and other hyperalimentation
0.655 0.345 0.000
H30-H36 Disorders of choroid and retina
0.655 0.345 0.000
D12.2 Ascending colon
0.655 0.345 0.000
N19 Unspecified renal failure
0.655 0.345 0.000
J30-J39 Other diseases of upper respiratory tract
0.655 0.345 0.000
I71 Aortic aneurysm and dissection
0.653 0.347 0.000
M65-M68 Disorders of synovium and tendon
0.652 0.348 0.000
S20-S29 Injuries to the thorax
0.652 0.348 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.652 0.348 0.000
I24.8 Other forms of acute ischaemic heart disease
0.651 0.349 0.000
S50-S59 Injuries to the elbow and forearm
0.651 0.349 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.651 0.349 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.651 0.349 0.000
C21 Malignant neoplasm of anus and anal canal
0.651 0.349 0.000
C17 Malignant neoplasm of small intestine
0.651 0.349 0.000
C23 Malignant neoplasm of gallbladder
0.651 0.349 0.000
Z41 Procedures for purposes other than remedying health state
0.651 0.349 0.000
N18.3 Chronic kidney disease, stage 3
0.650 0.349 0.000
M49 Spondylopathies in diseases classified elsewhere
0.650 0.350 0.000
G20 Parkinson's disease
0.650 0.350 0.000
D23.4 Skin of scalp and neck
0.650 0.350 0.000
N18.4 Chronic kidney disease, stage 4
0.649 0.350 0.000
M47.9 Spondylosis, unspecified
0.649 0.351 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.649 0.351 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.648 0.352 0.000
F03 Unspecified dementia
0.647 0.353 0.000
C50 Malignant neoplasm of breast
0.647 0.353 0.000
E83.4 Disorders of magnesium metabolism
0.647 0.353 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.646 0.353 0.000
R69 Unknown and unspecified causes of morbidity
0.646 0.354 0.000
L90.9 Atrophic disorder of skin, unspecified
0.646 0.354 0.000
L90.8 Other atrophic disorders of skin
0.646 0.354 0.000
L90.6 Striae atrophicae
0.646 0.354 0.000
L90.4 Acrodermatitis chronica atrophicans
0.646 0.354 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.646 0.354 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.646 0.354 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.646 0.354 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.646 0.354 0.000
I74 Arterial embolism and thrombosis
0.645 0.355 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.645 0.355 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.645 0.355 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.645 0.355 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.645 0.355 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.645 0.355 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.645 0.355 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.645 0.355 0.000
I44 Atrioventricular and left bundle-branch block
0.645 0.355 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.644 0.356 0.000
Z57 Occupational exposure to risk-factors
0.644 0.356 0.000
N63 Unspecified lump in breast
0.644 0.356 0.000
Z47 Other orthopaedic follow-up care
0.644 0.356 0.000
I15 Secondary hypertension
0.644 0.356 0.000
I13 Hypertensive heart and renal disease
0.644 0.356 0.000
I11 Hypertensive heart disease
0.644 0.356 0.000
R06 Abnormalities of breathing
0.643 0.357 0.000
S90-S99 Injuries to the ankle and foot
0.643 0.357 0.000
J46 Status asthmaticus
0.643 0.357 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.642 0.358 0.000
O42 Premature rupture of membranes
0.642 0.358 0.000
N50.8 Other specified disorders of male genital organs
0.642 0.358 0.000
D36 Benign neoplasm of other and unspecified sites
0.641 0.359 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.641 0.359 0.000
D04 Carcinoma in situ of skin
0.641 0.359 0.000
F99 Mental disorder, not otherwise specified
0.641 0.359 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.640 0.360 0.000
I52 Other heart disorders in diseases classified elsewhere
0.640 0.360 0.000
I48 Atrial fibrillation and flutter
0.640 0.360 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.640 0.360 0.000
I41 Myocarditis in diseases classified elsewhere
0.640 0.360 0.000
I40 Acute myocarditis
0.640 0.360 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.640 0.360 0.000
I37 Pulmonary valve disorders
0.640 0.360 0.000
I36 Nonrheumatic tricuspid valve disorders
0.640 0.360 0.000
I33 Acute and subacute endocarditis
0.640 0.360 0.000
I32 Pericarditis in diseases classified elsewhere
0.640 0.360 0.000
Z54 Convalescence
0.640 0.360 0.000
Z44 Fitting and adjustment of external prosthetic device
0.640 0.360 0.000
C18.7 Sigmoid colon
0.639 0.361 0.000
E14.3 With ophthalmic complications
0.639 0.361 0.000
Z51.9 Medical care, unspecified
0.639 0.361 0.000
Z51.6 Desensitisation to allergens
0.639 0.361 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.638 0.362 0.000
C80 Malignant neoplasm without specification of site
0.638 0.362 0.000
M75.8 Other shoulder lesions
0.637 0.363 0.000
M75.9 Shoulder lesion, unspecified
0.637 0.363 0.000
M75.2 Bicipital tendinitis
0.637 0.363 0.000
I78 Diseases of capillaries
0.636 0.364 0.000
R60.0 Localised oedema
0.636 0.364 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.635 0.365 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.635 0.365 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.635 0.365 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.635 0.365 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.635 0.365 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.635 0.365 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.634 0.366 0.000
M05 Seropositive rheumatoid arthritis
0.634 0.366 0.000
Q60-Q64 Congenital malformations of the urinary system
0.634 0.366 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.633 0.367 0.000
D23.5 Skin of trunk
0.633 0.367 0.000
Z04 Examination and observation for other reasons
0.632 0.368 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.632 0.368 0.000
E06 Thyroiditis
0.631 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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