TreeWAS – Variant ID: rs72833265

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I30-I52 Other forms of heart disease	1.000	0.000
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
I51 Complications and ill-defined descriptions of heart disease	0.999	0.001
I51.7 Cardiomegaly	0.997	0.003
Chapter VIII Diseases of the ear and mastoid process	0.997	0.003
Chapter V Mental and behavioural disorders	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
M45-M49 Spondylopathies	0.995	0.005
I42 Cardiomyopathy	0.995	0.005
Chapter IX Diseases of the circulatory system	0.995	0.005
I35 Nonrheumatic aortic valve disorders	0.994	0.006
S00-S09 Injuries to the head	0.988	0.012
F30-F39 Mood [affective] disorders	0.987	0.013
I35.0 Aortic (valve) stenosis	0.984	0.016
H80-H83 Diseases of inner ear	0.983	0.017
I42.0 Dilated cardiomyopathy	0.979	0.021
H81 Disorders of vestibular function	0.973	0.027
I51.9 Heart disease, unspecified	0.971	0.029
M05-M14 Inflammatory polyarthropathies	0.966	0.034
M48 Other spondylopathies	0.965	0.035
H81.0 Meniere's disease	0.964	0.036
S01 Open wound of head	0.958	0.042
Chapter XX External causes of morbidity and mortality	0.957	0.043
I34 Nonrheumatic mitral valve disorders	0.953	0.047
I42.9 Cardiomyopathy, unspecified	0.947	0.053
M48.0 Spinal stenosis	0.946	0.054
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.946	0.054
M10 Gout	0.945	0.055
M47 Spondylosis	0.940	0.060
F33 Recurrent depressive disorder	0.940	0.060
M48.06 Spinal stenosis (Lumbar region)	0.938	0.062
I44 Atrioventricular and left bundle-branch block	0.936	0.064
S60-S69 Injuries to the wrist and hand	0.931	0.069
F00-F09 Organic, including symptomatic, mental disorders	0.931	0.069
M10.9 Gout, unspecified	0.930	0.070
S00 Superficial injury of head	0.930	0.070
S01.0 Open wound of scalp	0.926	0.074
I35.2 Aortic (valve) stenosis with insufficiency	0.908	0.091
I44.7 Left bundle-branch block, unspecified	0.899	0.101
M86-M90 Other osteopathies	0.899	0.101
H60-H62 Diseases of external ear	0.894	0.106
M10.99 Gout, unspecified (Site unspecified)	0.893	0.107
F31 Bipolar affective disorder	0.889	0.111
M50-M54 Other dorsopathies	0.889	0.111
I50 Heart failure	0.887	0.113
M47.9 Spondylosis, unspecified	0.882	0.118
F40-F48 Neurotic, stress-related and somatoform disorders	0.875	0.125
S60 Superficial injury of wrist and hand	0.873	0.127
S80-S89 Injuries to the knee and lower leg	0.870	0.130
F03 Unspecified dementia	0.868	0.132
H90-H95 Other disorders of ear	0.862	0.138
F99-F99 Unspecified mental disorder	0.860	0.140
M80-M85 Disorders of bone density and structure	0.860	0.140
M54 Dorsalgia	0.854	0.146
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.853	0.147
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.850	0.150
S00.8 Superficial injury of other parts of head	0.848	0.152
M47.96 Spondylosis, unspecified (Lumbar region)	0.845	0.155
I05-I09 Chronic rheumatic heart diseases	0.843	0.157
T20-T25 Burns and corrosions of external body surface, specified by site	0.841	0.159
I30 Acute pericarditis	0.840	0.160
S00.7 Multiple superficial injuries of head	0.839	0.160
F41 Other anxiety disorders	0.839	0.161
I50.1 Left ventricular failure	0.838	0.162
I47 Paroxysmal tachycardia	0.837	0.163
F39 Unspecified mood [affective] disorder	0.835	0.165
M10.96 Gout, unspecified (Lower leg)	0.832	0.168
S01.9 Open wound of head, part unspecified	0.829	0.171
I34.0 Mitral (valve) insufficiency	0.821	0.179
F33.1 Recurrent depressive disorder, current episode moderate	0.821	0.179
M45 Ankylosing spondylitis	0.820	0.180
Q20-Q28 Congenital malformations of the circulatory system	0.819	0.181
S60.8 Other superficial injuries of wrist and hand	0.819	0.181
I33 Acute and subacute endocarditis	0.815	0.185
F30 Manic episode	0.812	0.188
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.812	0.188
S02 Fracture of skull and facial bones	0.810	0.190
S01.5 Open wound of lip and oral cavity	0.809	0.191
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.808	0.192
H61 Other disorders of external ear	0.808	0.192
H65-H75 Diseases of middle ear and mastoid	0.807	0.193
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.804	0.196
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.803	0.197
S05 Injury of eye and orbit	0.802	0.198
M70-M79 Other soft tissue disorders	0.802	0.198
I38 Endocarditis, valve unspecified	0.801	0.199
M54.5 Low back pain	0.800	0.200
M88 Paget's disease of bone [osteitis deformans]	0.799	0.201
F41.9 Anxiety disorder, unspecified	0.798	0.202
M60-M63 Disorders of muscles	0.798	0.202
T79-T79 Certain early complications of trauma	0.795	0.205
I34.2 Nonrheumatic mitral (valve) stenosis	0.795	0.205
I34.1 Mitral (valve) prolapse	0.794	0.206
S10-S19 Injuries to the neck	0.790	0.210
F41.2 Mixed anxiety and depressive disorder	0.789	0.211
M40-M43 Deforming dorsopathies	0.787	0.213
M47.1 Other spondylosis with myelopathy	0.787	0.213
Q60-Q64 Congenital malformations of the urinary system	0.786	0.214
S68 Traumatic amputation of wrist and hand	0.782	0.217
F31.9 Bipolar affective disorder, unspecified	0.779	0.221
F00 Dementia in Alzheimer's disease	0.776	0.223
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.776	0.224
Y52 Agents primarily affecting the cardiovascular system	0.775	0.225
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.774	0.226
W50-W64 Exposure to animate mechanical forces	0.771	0.229
M11 Other crystal arthropathies	0.770	0.230
M46 Other inflammatory spondylopathies	0.765	0.235
I44.3 Other and unspecified atrioventricular block	0.764	0.236
F99 Mental disorder, not otherwise specified	0.762	0.238
S00.3 Superficial injury of nose	0.762	0.238
S62 Fracture at wrist and hand level	0.762	0.238
M54.2 Cervicalgia	0.761	0.239
M47.8 Other spondylosis	0.760	0.240
M81 Osteoporosis without pathological fracture	0.760	0.240
F60-F69 Disorders of adult personality and behaviour	0.759	0.240
T15-T19 Effects of foreign body entering through natural orifice	0.759	0.241
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.757	0.243
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.757	0.243
I47.2 Ventricular tachycardia	0.755	0.245
H83 Other diseases of inner ear	0.754	0.246
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.753	0.247
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.753	0.247
I49 Other cardiac arrhythmias	0.753	0.247
V40-V49 Car occupant injured in transport accident	0.753	0.247
I45 Other conduction disorders	0.752	0.248
I44.6 Other and unspecified fascicular block	0.752	0.248
M89 Other disorders of bone	0.751	0.249
Y85 Sequelae of transport accidents	0.750	0.250
S01.2 Open wound of nose	0.748	0.252
Q80-Q89 Other congenital malformations	0.746	0.254
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.743	0.257
I36 Nonrheumatic tricuspid valve disorders	0.742	0.258
V80-V89 Other land transport accidents	0.740	0.260
M48.09 Spinal stenosis (Site unspecified)	0.737	0.263
F33.9 Recurrent depressive disorder, unspecified	0.737	0.263
I35.8 Other aortic valve disorders	0.737	0.263
H81.1 Benign paroxysmal vertigo	0.735	0.265
I42.6 Alcoholic cardiomyopathy	0.735	0.265
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.735	0.265
M10.90 Gout, unspecified (Multiple sites)	0.734	0.266
S66 Injury of muscle and tendon at wrist and hand level	0.733	0.267
I70-I79 Diseases of arteries, arterioles and capillaries	0.733	0.267
M00-M03 Infectious arthropathies	0.732	0.268
I42.2 Other hypertrophic cardiomyopathy	0.732	0.268
H72 Perforation of tympanic membrane	0.731	0.269
S64 Injury of nerves at wrist and hand level	0.728	0.272
I51.0 Cardiac septal defect, acquired	0.728	0.272
M48.00 Spinal stenosis (Multiple sites in spine)	0.728	0.272
T91 Sequelae of injuries of neck and trunk	0.727	0.273
M88.9 Paget's disease of bone, unspecified	0.727	0.273
H61.2 Impacted cerumen	0.724	0.276
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.724	0.276
H93 Other disorders of ear, not elsewhere classified	0.722	0.277
X58-X59 Accidental exposure to other and unspecified factors	0.722	0.278
S81 Open wound of lower leg	0.721	0.279
F80-F89 Disorders of psychological development	0.720	0.280
I08 Multiple valve diseases	0.719	0.281
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I51.6 Cardiovascular disease, unspecified	0.716	0.283
I51.5 Myocardial degeneration	0.716	0.283
I51.3 Intracardiac thrombosis, not elsewhere classified	0.716	0.283
I51.2 Rupture of papillary muscle, not elsewhere classified	0.716	0.283
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.716	0.283
S82 Fracture of lower leg, including ankle	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.285
F70-F79 Mental retardation	0.714	0.285
T33-T35 Frostbite	0.714	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.285
T00-T07 Injuries involving multiple body regions	0.714	0.285
Y00-Y09 Assault	0.714	0.286
M49 Spondylopathies in diseases classified elsewhere	0.713	0.286
I42.7 Cardiomyopathy due to drugs and other external agents	0.713	0.286
I42.5 Other restrictive cardiomyopathy	0.713	0.286
I42.4 Endocardial fibroelastosis	0.713	0.286
I42.3 Endomyocardial (eosinophilic) disease	0.713	0.286
I44.0 Atrioventricular block, first degree	0.713	0.287
I00-I02 Acute rheumatic fever	0.713	0.287
I46 Cardiac arrest	0.712	0.288
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.710	0.290
M47.94 Spondylosis, unspecified (Thoracic region)	0.710	0.290
S08 Traumatic amputation of part of head	0.708	0.292
S07 Crushing injury of head	0.708	0.292
S04 Injury of cranial nerves	0.708	0.292
S03 Dislocation, sprain and strain of joints and ligaments of head	0.708	0.292
F38 Other mood [affective] disorders	0.707	0.293
F34 Persistent mood [affective] disorders	0.707	0.293
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.707	0.293
M71 Other bursopathies	0.707	0.293
H74 Other disorders of middle ear and mastoid	0.707	0.293
F02 Dementia in other diseases classified elsewhere	0.705	0.294
I37 Pulmonary valve disorders	0.705	0.295
Chapter VII Diseases of the eye and adnexa	0.705	0.295
H82 Vertiginous syndromes in diseases classified elsewhere	0.705	0.295
I30.1 Infective pericarditis	0.703	0.297
S01.4 Open wound of cheek and temporomandibular area	0.700	0.300
F30.9 Manic episode, unspecified	0.699	0.301
Q50-Q56 Congenital malformations of genital organs	0.699	0.301
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.698	0.302
I51.4 Myocarditis, unspecified	0.698	0.302
H61.9 Disorder of external ear, unspecified	0.698	0.302
H81.9 Disorder of vestibular function, unspecified	0.697	0.302
H81.8 Other disorders of vestibular function	0.697	0.302
H81.4 Vertigo of central origin	0.697	0.302
H81.3 Other peripheral vertigo	0.697	0.302
H81.2 Vestibular neuronitis	0.697	0.302
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.697	0.303
Y95 Nosocomial condition	0.695	0.305
Y40 Systemic antibiotics	0.695	0.305
M54.56 Low back pain (Lumbar region)	0.693	0.307
M14 Arthropathies in other diseases classified elsewhere	0.692	0.307
M12 Other specific arthropathies	0.692	0.307
M09 Juvenile arthritis in diseases classified elsewhere	0.692	0.307
M08 Juvenile arthritis	0.692	0.307
X60-X84 Intentional self-harm	0.692	0.307
X20-X29 Contact with venomous animals and plants	0.692	0.308
M48.9 Spondylopathy, unspecified	0.692	0.308
M48.8 Other specified spondylopathies	0.692	0.308
M48.4 Fatigue fracture of vertebra	0.692	0.308
M48.3 Traumatic spondylopathy	0.692	0.308
M48.2 Kissing spine	0.692	0.308
M48.1 Ankylosing hyperostosis [Forestier]	0.692	0.308
H61.1 Non-infective disorders of pinna	0.691	0.309
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.691	0.309
M91-M94 Chondropathies	0.690	0.310
M54.22 Cervicalgia (Cervical region)	0.689	0.311
T36-T50 Poisoning by drugs, medicaments and biological substances	0.688	0.312
T20 Burn and corrosion of head and neck	0.688	0.312
Q23 Congenital malformations of aortic and mitral valves	0.687	0.313
Y35-Y36 Legal intervention and operations of war	0.686	0.314
Y10-Y34 Event of undetermined intent	0.686	0.314
X85-X99 Assault	0.686	0.314
X30-X39 Exposure to forces of nature	0.686	0.314
X10-X19 Contact with heat and hot substances	0.686	0.314
X00-X09 Exposure to smoke, fire and flames	0.686	0.314
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.686	0.314
W75-W84 Other accidental threats to breathing	0.686	0.314
W65-W74 Accidental drowning and submersion	0.686	0.314
V98-V99 Other and unspecified transport accidents	0.686	0.314
V95-V97 Air and space transport accidents	0.686	0.314
V90-V94 Water transport accidents	0.686	0.314
V70-V79 Bus occupant injured in transport accident	0.686	0.314
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.686	0.314
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.686	0.314
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.686	0.314
V01-V09 Pedestrian injured in transport accident	0.686	0.314
I42.1 Obstructive hypertrophic cardiomyopathy	0.686	0.314
S62.6 Fracture of other finger	0.685	0.315
I71 Aortic aneurysm and dissection	0.685	0.315
S70-S79 Injuries to the hip and thigh	0.684	0.316
M13 Other arthritis	0.684	0.316
I34.8 Other nonrheumatic mitral valve disorders	0.683	0.317
I33.0 Acute and subacute infective endocarditis	0.683	0.317
X40-X49 Accidental poisoning by and exposure to noxious substances	0.682	0.318
I35.1 Aortic (valve) insufficiency	0.682	0.318
S89 Other and unspecified injuries of lower leg	0.681	0.319
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.678	0.321
M48.05 Spinal stenosis (Thoracolumbar region)	0.678	0.321
M48.04 Spinal stenosis (Thoracic region)	0.678	0.321
M48.03 Spinal stenosis (Cervicothoracic region)	0.678	0.321
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.678	0.321
S65 Injury of blood vessels at wrist and hand level	0.678	0.322
S86 Injury of muscle and tendon at lower leg level	0.678	0.322
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.678	0.322
Q35-Q37 Cleft lip and cleft palate	0.678	0.322
Q30-Q34 Congenital malformations of the respiratory system	0.678	0.322
H60 Otitis externa	0.678	0.322
M10.4 Other secondary gout	0.677	0.322
M10.3 Gout due to impairment of renal function	0.677	0.322
M10.2 Drug-induced gout	0.677	0.322
M10.1 Lead-induced gout	0.677	0.322
M10.0 Idiopathic gout	0.677	0.322
M47.12 Other spondylosis with myelopathy (Cervical region)	0.677	0.323
Y53 Agents primarily affecting the gastro-intestinal system	0.676	0.324
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.676	0.324
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.675	0.325
M47.0 Anterior spinal and vertebral artery compression syndromes	0.674	0.326
F33.8 Other recurrent depressive disorders	0.674	0.326
F33.4 Recurrent depressive disorder, currently in remission	0.674	0.326
F33.0 Recurrent depressive disorder, current episode mild	0.674	0.326
Q38-Q45 Other congenital malformations of the digestive system	0.673	0.327
S60.0 Contusion of finger(s) without damage to nail	0.673	0.327
M85 Other disorders of bone density and structure	0.671	0.328
I44.5 Left posterior fascicular block	0.671	0.329
I44.4 Left anterior fascicular block	0.671	0.329
S00.2 Other superficial injuries of eyelid and periocular area	0.671	0.329
M47.99 Spondylosis, unspecified (Site unspecified)	0.670	0.330
M45.X9 Ankylosing spondylitis (Site unspecified)	0.669	0.331
S01.7 Multiple open wounds of head	0.668	0.332
M54.9 Dorsalgia, unspecified	0.668	0.332
T65 Toxic effect of other and unspecified substances	0.668	0.332
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.667	0.332
Q00-Q07 Congenital malformations of the nervous system	0.667	0.333
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.667	0.333
F09 Unspecified organic or symptomatic mental disorder	0.667	0.333
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.667	0.333
M10.98 Gout, unspecified (Other)	0.667	0.333
M10.95 Gout, unspecified (Pelvic region and thigh)	0.667	0.333
M10.94 Gout, unspecified (Hand)	0.667	0.333
M10.93 Gout, unspecified (Forearm)	0.667	0.333
M10.92 Gout, unspecified (Upper arm)	0.667	0.333
M10.91 Gout, unspecified (Shoulder region)	0.667	0.333
S00.5 Superficial injury of lip and oral cavity	0.667	0.333
S00.4 Superficial injury of ear	0.667	0.333
M81.9 Osteoporosis, unspecified	0.667	0.333
F00.9 Dementia in Alzheimer's disease, unspecified	0.666	0.334
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.665	0.335
I05 Rheumatic mitral valve diseases	0.664	0.336
M76 Enthesopathies of lower limb, excluding foot	0.664	0.336
S69 Other and unspecified injuries of wrist and hand	0.662	0.338
Q60 Renal agenesis and other reduction defects of kidney	0.661	0.339
M54.4 Lumbago with sciatica	0.659	0.340
Y52.4 Angiotensin-converting-enzyme inhibitors	0.658	0.342
M10.97 Gout, unspecified (Ankle and foot)	0.658	0.342
F01 Vascular dementia	0.657	0.343
H80 Otosclerosis	0.656	0.344
Y57 Other and unspecified drugs and medicaments	0.655	0.345
M05 Seropositive rheumatoid arthritis	0.655	0.345
X50-X57 Overexertion, travel and privation	0.654	0.345
F31.0 Bipolar affective disorder, current episode hypomanic	0.654	0.346
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.654	0.346
M62 Other disorders of muscle	0.654	0.346
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.653	0.347
S60.2 Contusion of other parts of wrist and hand	0.653	0.347
M07 Psoriatic and enteropathic arthropathies	0.653	0.347
M70 Soft tissue disorders related to use, overuse and pressure	0.653	0.347
H55-H59 Other disorders of eye and adnexa	0.652	0.348
W20-W49 Exposure to inanimate mechanical forces	0.651	0.348
T79 Certain early complications of trauma, not elsewhere classified	0.651	0.349
V10-V19 Pedal cyclist injured in transport accident	0.648	0.352
V20-V29 Motorcycle rider injured in transport accident	0.647	0.353
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.647	0.353
I50.9 Heart failure, unspecified	0.647	0.353
S00.9 Superficial injury of head, part unspecified	0.646	0.353
Y41 Other systemic anti-infectives and antiparasitics	0.646	0.354
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.646	0.354
M47.82 Other spondylosis (Cervical region)	0.644	0.356
S67 Crushing injury of wrist and hand	0.643	0.357
T23 Burn and corrosion of wrist and hand	0.642	0.357
Y85.9 Sequelae of other and unspecified transport accidents	0.642	0.358
Q24 Other congenital malformations of heart	0.642	0.358
M54.59 Low back pain (Site unspecified)	0.641	0.359
I30.9 Acute pericarditis, unspecified	0.641	0.359
H62 Disorders of external ear in diseases classified elsewhere	0.641	0.359
M48.5 Collapsed vertebra, not elsewhere classified	0.641	0.359
M87 Osteonecrosis	0.640	0.360
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.640	0.360
Q25 Congenital malformations of great arteries	0.639	0.360
M06 Other rheumatoid arthritis	0.639	0.361
M79 Other soft tissue disorders, not elsewhere classified	0.639	0.361
W55 Bitten or struck by other mammals	0.639	0.361
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.638	0.362
F31.8 Other bipolar affective disorders	0.638	0.362
F31.7 Bipolar affective disorder, currently in remission	0.638	0.362
F31.6 Bipolar affective disorder, current episode mixed	0.638	0.362
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.638	0.362
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.638	0.362
M54.50 Low back pain (Multiple sites in spine)	0.637	0.363
S02.5 Fracture of tooth	0.636	0.363
Y60-Y69 Misadventures to patients during surgical and medical care	0.636	0.364
H90 Conductive and sensorineural hearing loss	0.636	0.364
S82.1 Fracture of upper end of tibia	0.635	0.365
H40-H42 Glaucoma	0.635	0.365
M82 Osteoporosis in diseases classified elsewhere	0.633	0.366
M45.X2 Ankylosing spondylitis (Cervical region)	0.633	0.367
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.633	0.367
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.633	0.367
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.633	0.367
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.633	0.367
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.633	0.367
W00-W19 Falls	0.632	0.367
Q61 Cystic kidney disease	0.632	0.368
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.631	0.369
M11.2 Other chondrocalcinosis	0.630	0.370
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.630	0.370
S01.1 Open wound of eyelid and periocular area	0.630	0.370
Chapter XXII Codes for special purposes	0.629	0.371
I44.1 Atrioventricular block, second degree	0.629	0.371
M65-M68 Disorders of synovium and tendon	0.629	0.371
I49.4 Other and unspecified premature depolarisation	0.629	0.371
S82.4 Fracture of fibula alone	0.628	0.372
F32 Depressive episode	0.628	0.372
F48 Other neurotic disorders	0.627	0.373
F44 Dissociative [conversion] disorders	0.627	0.373
Y88 Sequelae of surgical and medical care as external cause	0.627	0.373
S60.7 Multiple superficial injuries of wrist and hand	0.626	0.374
S60.1 Contusion of finger(s) with damage to nail	0.626	0.374
H95.1 Other disorders following mastoidectomy	0.624	0.376
M90 Osteopathies in diseases classified elsewhere	0.624	0.376
S88 Traumatic amputation of lower leg	0.624	0.376
S87 Crushing injury of lower leg	0.624	0.376
S85 Injury of blood vessels at lower leg level	0.624	0.376
S84 Injury of nerves at lower leg level	0.624	0.376
I42.8 Other cardiomyopathies	0.623	0.376
Chapter I Certain infectious and parasitic diseases	0.623	0.377
M53 Other dorsopathies, not elsewhere classified	0.622	0.378
S02.6 Fracture of mandible	0.622	0.378
M71.2 Synovial cyst of popliteal space [Baker]	0.621	0.379
M41 Scoliosis	0.619	0.381
T31 Burns classified according to extent of body surface involved	0.619	0.381
S05.1 Contusion of eyeball and orbital tissues	0.618	0.381
M54.55 Low back pain (Thoracolumbar region)	0.618	0.382
H94 Other disorders of ear in diseases classified elsewhere	0.618	0.382
M83 Adult osteomalacia	0.616	0.384
V49 Car occupant injured in other and unspecified transport accidents	0.616	0.384
I49.9 Cardiac arrhythmia, unspecified	0.615	0.385
S62.61 Fracture of other finger (open)	0.615	0.385
S81.9 Open wound of lower leg, part unspecified	0.615	0.385
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.615	0.385
M86 Osteomyelitis	0.614	0.385
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.613	0.387
M54.8 Other dorsalgia	0.613	0.387
M54.0 Panniculitis affecting regions of neck and back	0.613	0.387
S10 Superficial injury of neck	0.612	0.388
M81.2 Osteoporosis of disuse	0.612	0.388
M51 Other intervertebral disk disorders	0.612	0.388
Y59 Other and unspecified vaccines and biological substances	0.612	0.388
Y58 Bacterial vaccines	0.612	0.388
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.612	0.388
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.612	0.388
Y50 Central nervous system stimulants, not elsewhere classified	0.612	0.388
Y49 Psychotropic drugs, not elsewhere classified	0.612	0.388
Y48 Anaesthetics and therapeutic gases	0.612	0.388
Y47 Sedatives, hypnotics and antianxiety drugs	0.612	0.388
Y46 Antiepileptics and anti-Parkinsonism drugs	0.612	0.388
Y86 Sequelae of other accidents	0.611	0.389
M89.5 Osteolysis	0.610	0.390
S02.1 Fracture of base of skull	0.610	0.390
Y85.0 Sequelae of motor-vehicle accident	0.610	0.390
T92 Sequelae of injuries of upper limb	0.610	0.390
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.610	0.390
T94 Sequelae of injuries involving multiple and unspecified body regions	0.610	0.390
S32 Fracture of lumbar spine and pelvis	0.609	0.391
Y89 Sequelae of other external causes	0.609	0.391
H93.8 Other specified disorders of ear	0.607	0.393
I70 Atherosclerosis	0.607	0.393
S20-S29 Injuries to the thorax	0.606	0.394
Y91 Evidence of alcohol involvement determined by level of intoxication	0.605	0.394
S00.0 Superficial injury of scalp	0.605	0.395
M80 Osteoporosis with pathological fracture	0.605	0.395
I09 Other rheumatic heart diseases	0.604	0.395
I06 Rheumatic aortic valve diseases	0.604	0.395
H72.8 Other perforations of tympanic membrane	0.604	0.396
F69 Unspecified disorder of adult personality and behaviour	0.604	0.396
T91.9 Sequelae of unspecified injury of neck and trunk	0.604	0.396
S60.9 Superficial injury of wrist and hand, unspecified	0.603	0.397
T25 Burn and corrosion of ankle and foot	0.603	0.397
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.603	0.397
T21 Burn and corrosion of trunk	0.603	0.397
I30.8 Other forms of acute pericarditis	0.602	0.398
I30.0 Acute nonspecific idiopathic pericarditis	0.602	0.398
F41.8 Other specified anxiety disorders	0.602	0.398
F41.3 Other mixed anxiety disorders	0.602	0.398
S02.3 Fracture of orbital floor	0.601	0.399
M46.9 Inflammatory spondylopathy, unspecified	0.601	0.399
I31 Other diseases of pericardium	0.600	0.400
I47.0 Reentry ventricular arrhythmia	0.600	0.400
M77 Other enthesopathies	0.599	0.401
S02.9 Fracture of skull and facial bones, part unspecified	0.599	0.401
T66-T78 Other and unspecified effects of external causes	0.598	0.402
H74.4 Polyp of middle ear	0.596	0.404
F42 Obsessive-compulsive disorder	0.596	0.404
F45 Somatoform disorders	0.596	0.404
S09 Other and unspecified injuries of head	0.595	0.404
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.595	0.405
I45.8 Other specified conduction disorders	0.595	0.405
T91.2 Sequelae of other fracture of thorax and pelvis	0.593	0.407
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.592	0.408
Q23.1 Congenital insufficiency of aortic valve	0.592	0.408
H66 Suppurative and unspecified otitis media	0.591	0.409
H91 Other hearing loss	0.591	0.409
S12 Fracture of neck	0.590	0.409
M89.9 Disorder of bone, unspecified	0.590	0.410
H83.0 Labyrinthitis	0.590	0.410
S02.8 Fractures of other skull and facial bones	0.588	0.412
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.588	0.412
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.588	0.412
M45.X6 Ankylosing spondylitis (Lumbar region)	0.588	0.412
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.588	0.412
M45.X4 Ankylosing spondylitis (Thoracic region)	0.588	0.412
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.588	0.412
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.588	0.412
Q27 Other congenital malformations of peripheral vascular system	0.587	0.413
Q26 Congenital malformations of great veins	0.587	0.413
Q22 Congenital malformations of pulmonary and tricuspid valves	0.587	0.413
Q20 Congenital malformations of cardiac chambers and connexions	0.587	0.413
T14 Injury of unspecified body region	0.586	0.414
M43 Other deforming dorsopathies	0.585	0.415
H40 Glaucoma	0.585	0.415
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.585	0.415
H55 Nystagmus and other irregular eye movements	0.585	0.415
I33.9 Acute endocarditis, unspecified	0.584	0.415
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.584	0.416

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations