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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72850953
log Bayes Factor = 8.10331
Chromosome 11   position 1,771,871  (GRCh37) Explore rs72850953 on Ensembl!
Variant rs72850953 is part of Cluster X0053

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.998 0.002 0.000
T81 Complications of procedures, not elsewhere classified
0.998 0.002 0.000
Chapter II Neoplasms
0.995 0.005 0.000
R26 Abnormalities of gait and mobility
0.991 0.009 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
C15-C26 Malignant neoplasms of digestive organs
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
R47-R49 Symptoms and signs involving speech and voice
0.979 0.021 0.000
O60-O75 Complications of labour and delivery
0.976 0.024 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.965 0.035 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.957 0.043 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.955 0.045 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.951 0.049 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.944 0.056 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.940 0.060 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.932 0.068 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.931 0.069 0.000
R49 Voice disturbances
0.927 0.073 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.922 0.078 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.918 0.082 0.000
O63 Long labour
0.912 0.088 0.000
C78.0 Secondary malignant neoplasm of lung
0.910 0.090 0.000
R47 Speech disturbances, not elsewhere classified
0.907 0.093 0.000
S60-S69 Injuries to the wrist and hand
0.904 0.096 0.000
Chapter VII Diseases of the eye and adnexa
0.902 0.098 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.898 0.102 0.000
R25 Abnormal involuntary movements
0.897 0.103 0.000
R49.0 Dysphonia
0.890 0.110 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.890 0.110 0.000
C51-C58 Malignant neoplasms of female genital organs
0.890 0.110 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.887 0.113 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.887 0.113 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.879 0.121 0.000
C44 Other malignant neoplasms of skin
0.875 0.125 0.000
C18 Malignant neoplasm of colon
0.873 0.127 0.000
Chapter XXII Codes for special purposes
0.872 0.128 0.000
W00-W19 Falls
0.871 0.129 0.000
Chapter VIII Diseases of the ear and mastoid process
0.866 0.134 0.000
T92 Sequelae of injuries of upper limb
0.865 0.135 0.000
Chapter VI Diseases of the nervous system
0.863 0.137 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.862 0.138 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.859 0.141 0.000
T90 Sequelae of injuries of head
0.859 0.141 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.858 0.142 0.000
S90-S99 Injuries to the ankle and foot
0.856 0.144 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.853 0.147 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.851 0.149 0.000
S40-S49 Injuries to the shoulder and upper arm
0.846 0.154 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.846 0.154 0.000
R47.1 Dysarthria and anarthria
0.844 0.156 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.844 0.156 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.839 0.161 0.000
O63.1 Prolonged second stage (of labour)
0.838 0.162 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.838 0.162 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.837 0.163 0.000
C91 Lymphoid leukaemia
0.835 0.165 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.835 0.165 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.832 0.168 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.831 0.169 0.000
T88.4 Failed or difficult intubation
0.831 0.169 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.830 0.170 0.000
C21 Malignant neoplasm of anus and anal canal
0.826 0.174 0.000
H53-H54 Visual disturbances and blindness
0.826 0.174 0.000
H52 Disorders of refraction and accommodation
0.822 0.178 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.821 0.179 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.820 0.180 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.820 0.180 0.000
S64 Injury of nerves at wrist and hand level
0.812 0.188 0.000
C18.2 Ascending colon
0.812 0.188 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.810 0.190 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.805 0.195 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.805 0.195 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.798 0.202 0.000
Q50-Q56 Congenital malformations of genital organs
0.797 0.203 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.796 0.204 0.000
M50-M54 Other dorsopathies
0.796 0.204 0.000
D80-D89 Certain disorders involving the immune mechanism
0.795 0.205 0.000
R26.0 Ataxic gait
0.793 0.207 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.792 0.208 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.792 0.208 0.000
C44.2 Skin of ear and external auricular canal
0.791 0.209 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.791 0.209 0.000
W50-W64 Exposure to animate mechanical forces
0.789 0.211 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.788 0.212 0.000
H52.1 Myopia
0.787 0.213 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.787 0.213 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.785 0.215 0.000
V40-V49 Car occupant injured in transport accident
0.782 0.218 0.000
T79-T79 Certain early complications of trauma
0.782 0.218 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.782 0.218 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.781 0.219 0.000
C78.7 Secondary malignant neoplasm of liver
0.780 0.220 0.000
S10-S19 Injuries to the neck
0.778 0.222 0.000
T43.2 Other and unspecified antidepressants
0.778 0.222 0.000
C44.4 Skin of scalp and neck
0.777 0.223 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.776 0.224 0.000
M51 Other intervertebral disk disorders
0.776 0.224 0.000
L03 Cellulitis
0.774 0.226 0.000
T86 Failure and rejection of transplanted organs and tissues
0.774 0.226 0.000
H54 Blindness and low vision
0.773 0.227 0.000
O66 Other obstructed labour
0.770 0.230 0.000
R25.1 Tremor, unspecified
0.769 0.231 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.769 0.231 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.768 0.232 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.765 0.235 0.000
O62 Abnormalities of forces of labour
0.763 0.237 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.762 0.237 0.000
T87 Complications peculiar to reattachment and amputation
0.761 0.239 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.761 0.239 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.760 0.240 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.760 0.240 0.000
O73 Retained placenta and membranes, without haemorrhage
0.759 0.241 0.000
Y95 Nosocomial condition
0.758 0.242 0.000
H50 Other strabismus
0.758 0.242 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.758 0.242 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.756 0.244 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.755 0.245 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.753 0.247 0.000
V10-V19 Pedal cyclist injured in transport accident
0.752 0.248 0.000
T92.0 Sequelae of open wound of upper limb
0.751 0.249 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.751 0.249 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.751 0.249 0.000
T91 Sequelae of injuries of neck and trunk
0.750 0.250 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.750 0.250 0.000
C44.0 Skin of lip
0.748 0.252 0.000
H65-H75 Diseases of middle ear and mastoid
0.747 0.253 0.000
Chapter V Mental and behavioural disorders
0.744 0.256 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.743 0.257 0.000
Y00-Y09 Assault
0.743 0.257 0.000
H90-H95 Other disorders of ear
0.743 0.257 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.742 0.258 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.742 0.258 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.741 0.259 0.000
C91.1 Chronic lymphocytic leukaemia
0.740 0.260 0.000
G70-G73 Diseases of myoneural junction and muscle
0.739 0.261 0.000
C17 Malignant neoplasm of small intestine
0.739 0.261 0.000
Y43 Primarily systemic agents
0.735 0.265 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.735 0.265 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.735 0.265 0.000
C81 Hodgkin's disease
0.733 0.267 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.733 0.267 0.000
C23 Malignant neoplasm of gallbladder
0.733 0.267 0.000
H49 Paralytic strabismus
0.733 0.267 0.000
T66-T78 Other and unspecified effects of external causes
0.733 0.267 0.000
R29.6 Tendency to fall, not elsewhere classified
0.733 0.267 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.731 0.269 0.000
C25 Malignant neoplasm of pancreas
0.731 0.269 0.000
C20 Malignant neoplasm of rectum
0.729 0.271 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.728 0.272 0.000
L50-L54 Urticaria and erythema
0.727 0.273 0.000
M50 Cervical disk disorders
0.726 0.274 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.726 0.274 0.000
L03.2 Cellulitis of face
0.725 0.275 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.725 0.275 0.000
Q80-Q89 Other congenital malformations
0.724 0.276 0.000
T90.4 Sequelae of injury of eye and orbit
0.724 0.276 0.000
X50-X57 Overexertion, travel and privation
0.722 0.278 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.722 0.278 0.000
G90-G99 Other disorders of the nervous system
0.719 0.281 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.719 0.281 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.719 0.281 0.000
Y44 Agents primarily affecting blood constituents
0.719 0.281 0.000
L05 Pilonidal cyst
0.719 0.281 0.000
D60-D64 Aplastic and other anaemias
0.718 0.282 0.000
W19 Unspecified fall
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C77.8 Lymph nodes of multiple regions
0.717 0.283 0.000
T88.5 Other complications of anaesthesia
0.716 0.284 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.716 0.284 0.000
M51.2 Other specified intervertebral disk displacement
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.715 0.285 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.715 0.285 0.000
Q51 Congenital malformations of uterus and cervix
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.712 0.287 0.000
C92 Myeloid leukaemia
0.712 0.288 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.712 0.288 0.000
M51.8 Other specified intervertebral disk disorders
0.711 0.289 0.000
R26.1 Paralytic gait
0.711 0.289 0.000
O63.9 Long labour, unspecified
0.711 0.289 0.000
C22.9 Liver, unspecified
0.710 0.290 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
W10 Fall on and from stairs and steps
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
O63.0 Prolonged first stage (of labour)
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
R73 Elevated blood glucose level
0.707 0.293 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.706 0.294 0.000
D86 Sarcoidosis
0.706 0.294 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.703 0.297 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.298 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.702 0.298 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.702 0.298 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.702 0.298 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.702 0.298 0.000
S60 Superficial injury of wrist and hand
0.701 0.299 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.701 0.299 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.701 0.299 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.701 0.299 0.000
C18.0 Caecum
0.701 0.299 0.000
C18.5 Splenic flexure
0.700 0.300 0.000
O74 Complications of anaesthesia during labour and delivery
0.700 0.300 0.000
O60 Preterm delivery
0.700 0.300 0.000
T93 Sequelae of injuries of lower limb
0.699 0.301 0.000
H71 Cholesteatoma of middle ear
0.699 0.301 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.698 0.302 0.000
C54 Malignant neoplasm of corpus uteri
0.698 0.302 0.000
T23 Burn and corrosion of wrist and hand
0.697 0.303 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.696 0.304 0.000
T98 Sequelae of other and unspecified effects of external causes
0.696 0.304 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.696 0.304 0.000
O71 Other obstetric trauma
0.696 0.304 0.000
S80-S89 Injuries to the knee and lower leg
0.694 0.305 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.694 0.306 0.000
C51 Malignant neoplasm of vulva
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.692 0.307 0.000
H10-H13 Disorders of conjunctiva
0.692 0.308 0.000
T95 Sequelae of burns, corrosions and frostbite
0.692 0.308 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.692 0.308 0.000
T81.9 Unspecified complication of procedure
0.689 0.310 0.000
Y42.7 Androgens and anabolic congeners
0.688 0.312 0.000
C91.0 Acute lymphoblastic leukaemia
0.687 0.312 0.000
W13 Fall from, out of or through building or structure
0.687 0.313 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.687 0.313 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.687 0.313 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.686 0.314 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.685 0.314 0.000
L03.0 Cellulitis of finger and toe
0.685 0.314 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.685 0.315 0.000
H60-H62 Diseases of external ear
0.685 0.315 0.000
R47.0 Dysphasia and aphasia
0.685 0.315 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.684 0.315 0.000
T88.9 Complication of surgical and medical care, unspecified
0.684 0.316 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.684 0.316 0.000
T88.2 Shock due to anaesthesia
0.684 0.316 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.684 0.316 0.000
T88.0 Infection following immunisation
0.684 0.316 0.000
R25.3 Fasciculation
0.684 0.316 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.684 0.316 0.000
C78.2 Secondary malignant neoplasm of pleura
0.683 0.317 0.000
R77 Other abnormalities of plasma proteins
0.683 0.317 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.683 0.317 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.682 0.318 0.000
S65 Injury of blood vessels at wrist and hand level
0.682 0.318 0.000
M50.2 Other cervical disk displacement
0.681 0.319 0.000
Chapter IX Diseases of the circulatory system
0.680 0.320 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.680 0.320 0.000
Q65 Congenital deformities of hip
0.680 0.320 0.000
T46.1 Calcium-channel blockers
0.679 0.320 0.000
C21.1 Anal canal
0.679 0.321 0.000
O85-O92 Complications predominantly related to the puerperium
0.679 0.321 0.000
D62 Acute posthaemorrhagic anaemia
0.678 0.322 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.677 0.323 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.677 0.323 0.000
C05 Malignant neoplasm of palate
0.676 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.324 0.000
Y48 Anaesthetics and therapeutic gases
0.676 0.324 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.675 0.325 0.000
W18 Other fall on same level
0.675 0.325 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.675 0.325 0.000
C22.1 Intrahepatic bile duct carcinoma
0.674 0.326 0.000
R29.4 Clicking hip
0.674 0.326 0.000
R29.3 Abnormal posture
0.674 0.326 0.000
R29.2 Abnormal reflex
0.674 0.326 0.000
R29.1 Meningismus
0.674 0.326 0.000
R29.0 Tetany
0.674 0.326 0.000
C44.1 Skin of eyelid, including canthus
0.674 0.326 0.000
Y57 Other and unspecified drugs and medicaments
0.673 0.327 0.000
C64-C68 Malignant neoplasms of urinary tract
0.673 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.672 0.327 0.000
S64.1 Injury of median nerve at wrist and hand level
0.671 0.329 0.000
T90.9 Sequelae of unspecified injury of head
0.671 0.329 0.000
F30-F39 Mood [affective] disorders
0.671 0.329 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.670 0.330 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.670 0.330 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.670 0.330 0.000
M60-M63 Disorders of muscles
0.669 0.331 0.000
T20 Burn and corrosion of head and neck
0.669 0.331 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.668 0.332 0.000
R27 Other lack of coordination
0.668 0.332 0.000
S91 Open wound of ankle and foot
0.667 0.332 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.333 0.000
O26.8 Other specified pregnancy-related conditions
0.667 0.333 0.000
S90 Superficial injury of ankle and foot
0.666 0.334 0.000
R49.8 Other and unspecified voice disturbances
0.665 0.335 0.000
R49.2 Hypernasality and hyponasality
0.665 0.335 0.000
R49.1 Aphonia
0.665 0.335 0.000
H18 Other disorders of cornea
0.665 0.335 0.000
T39.0 Salicylates
0.664 0.336 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.663 0.337 0.000
O61 Failed induction of labour
0.662 0.338 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.662 0.338 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.662 0.338 0.000
O23 Infections of genito-urinary tract in pregnancy
0.662 0.338 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.662 0.338 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.661 0.339 0.000
Q35-Q37 Cleft lip and cleft palate
0.661 0.339 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.661 0.339 0.000
H90 Conductive and sensorineural hearing loss
0.660 0.340 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.659 0.341 0.000
W17 Other fall from one level to another
0.659 0.341 0.000
D80 Immunodeficiency with predominantly antibody defects
0.658 0.342 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.658 0.342 0.000
C95 Leukaemia of unspecified cell type
0.658 0.342 0.000
C94 Other leukaemias of specified cell type
0.658 0.342 0.000
C93 Monocytic leukaemia
0.658 0.342 0.000
C86 Other specified types of T/NK-cell lymphoma
0.658 0.342 0.000
R47.8 Other and unspecified speech disturbances
0.658 0.342 0.000
T45.5 Anticoagulants
0.657 0.343 0.000
Y43.4 Immunosuppressive agents
0.657 0.343 0.000
S92 Fracture of foot, except ankle
0.657 0.343 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
C16 Malignant neoplasm of stomach
0.655 0.345 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.654 0.346 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.654 0.346 0.000
C18.6 Descending colon
0.652 0.348 0.000
O69.8 Labour and delivery complicated by other cord complications
0.652 0.348 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.651 0.349 0.000
Y86 Sequelae of other accidents
0.651 0.349 0.000
M50.0 Cervical disk disorder with myelopathy
0.651 0.349 0.000
H54.9 Unspecified visual impairment (binocular)
0.649 0.351 0.000
H17 Corneal scars and opacities
0.647 0.353 0.000
R45 Symptoms and signs involving emotional state
0.647 0.353 0.000
W55 Bitten or struck by other mammals
0.647 0.353 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.647 0.353 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.647 0.353 0.000
M40-M43 Deforming dorsopathies
0.646 0.354 0.000
H49.2 Sixth [abducent] nerve palsy
0.646 0.354 0.000
S42 Fracture of shoulder and upper arm
0.646 0.354 0.000
H52.3 Anisometropia and aniseikonia
0.645 0.355 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.643 0.357 0.000
R25.0 Abnormal head movements
0.643 0.357 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.643 0.357 0.000
C21.0 Anus, unspecified
0.643 0.357 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
O75.8 Other specified complications of labour and delivery
0.642 0.358 0.000
C88 Malignant immunoproliferative diseases
0.641 0.359 0.000
O28 Abnormal findings on antenatal screening of mother
0.640 0.360 0.000
S40 Superficial injury of shoulder and upper arm
0.640 0.360 0.000
I72 Other aneurysm
0.639 0.361 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.638 0.362 0.000
C58 Malignant neoplasm of placenta
0.638 0.362 0.000
C52 Malignant neoplasm of vagina
0.638 0.362 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.638 0.362 0.000
Q00-Q07 Congenital malformations of the nervous system
0.637 0.363 0.000
Y88 Sequelae of surgical and medical care as external cause
0.637 0.363 0.000
C44.7 Skin of lower limb, including hip
0.637 0.363 0.000
C53 Malignant neoplasm of cervix uteri
0.637 0.363 0.000
Q51.3 Bicornate uterus
0.637 0.363 0.000
R50-R69 General symptoms and signs
0.637 0.363 0.000
W19.3 Sports and athletics area
0.637 0.363 0.000
H54.7 Unspecified visual loss
0.636 0.364 0.000
T90.5 Sequelae of intracranial injury
0.636 0.364 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.636 0.364 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.636 0.364 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.635 0.365 0.000
S50-S59 Injuries to the elbow and forearm
0.635 0.365 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.635 0.365 0.000
C44.3 Skin of other and unspecified parts of face
0.635 0.365 0.000
H43-H45 Disorders of vitreous body and globe
0.634 0.366 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.634 0.366 0.000
C18.3 Hepatic flexure
0.634 0.366 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.634 0.366 0.000
S63.6 Sprain and strain of finger(s)
0.633 0.367 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.632 0.367 0.000
U80 Agent resistant to penicillin and related antibiotics
0.632 0.368 0.000
C09 Malignant neoplasm of tonsil
0.632 0.368 0.000
L20-L30 Dermatitis and eczema
0.631 0.368 0.000
C90.0 Multiple myeloma
0.631 0.369 0.000
H54.4 Blindness, one eye
0.631 0.369 0.000
H51 Other disorders of binocular movement
0.631 0.369 0.000
S61 Open wound of wrist and hand
0.630 0.370 0.000
M91-M94 Chondropathies
0.630 0.370 0.000
H21 Other disorders of iris and ciliary body
0.629 0.371 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.628 0.372 0.000
R25.2 Cramp and spasm
0.628 0.372 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.627 0.373 0.000
C44.8 Overlapping lesion of skin
0.627 0.373 0.000
C22.0 Liver cell carcinoma
0.627 0.373 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.627 0.373 0.000
R21 Rash and other nonspecific skin eruption
0.627 0.373 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.626 0.374 0.000
C18.8 Overlapping lesion of colon
0.626 0.374 0.000
G82 Paraplegia and tetraplegia
0.626 0.374 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.625 0.375 0.000
I74 Arterial embolism and thrombosis
0.625 0.375 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.624 0.375 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.624 0.375 0.000
W15 Fall from cliff
0.624 0.375 0.000
W14 Fall from tree
0.624 0.375 0.000
W12 Fall on and from scaffolding
0.624 0.375 0.000
W11 Fall on and from ladder
0.624 0.375 0.000
W09 Fall involving playground equipment
0.624 0.375 0.000
W05 Fall involving wheelchair
0.624 0.375 0.000
W04 Fall while being carried or supported by other persons
0.624 0.375 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.624 0.375 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.624 0.375 0.000
W00 Fall on same level involving ice and snow
0.624 0.375 0.000
H50.2 Vertical strabismus
0.623 0.376 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.622 0.378 0.000
M65-M68 Disorders of synovium and tendon
0.622 0.378 0.000
Q76 Congenital malformations of spine and bony thorax
0.622 0.378 0.000
G72 Other myopathies
0.622 0.378 0.000
I73 Other peripheral vascular diseases
0.622 0.378 0.000
D75 Other diseases of blood and blood-forming organs
0.620 0.379 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.620 0.380 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.620 0.380 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.620 0.380 0.000
R20 Disturbances of skin sensation
0.620 0.380 0.000
G71 Primary disorders of muscles
0.620 0.380 0.000
S69 Other and unspecified injuries of wrist and hand
0.619 0.381 0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs
0.619 0.381 0.000
Chapter X Diseases of the respiratory system
0.619 0.381 0.000
S43.0 Dislocation of shoulder joint
0.618 0.382 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.618 0.382 0.000
T39.4 Antirheumatics, not elsewhere classified
0.618 0.382 0.000
T39.2 Pyrazolone derivatives
0.618 0.382 0.000
R74 Abnormal serum enzyme levels
0.618 0.382 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.618 0.382 0.000
S64.4 Injury of digital nerve of other finger
0.617 0.383 0.000
L10-L14 Bullous disorders
0.616 0.384 0.000
T90.8 Sequelae of other specified injuries of head
0.616 0.384 0.000
T90.3 Sequelae of injury of cranial nerves
0.616 0.384 0.000
T90.1 Sequelae of open wound of head
0.616 0.384 0.000
T90.0 Sequelae of superficial injury of head
0.616 0.384 0.000
Y42.9 Other and unspecified hormone antagonists
0.615 0.385 0.000
Y42.4 Oral contraceptives
0.615 0.385 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.615 0.385 0.000
Y42.2 Antithyroid drugs
0.615 0.385 0.000
Y42.1 Thyroid hormones and substitutes
0.615 0.385 0.000
O21 Excessive vomiting in pregnancy
0.615 0.385 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.615 0.385 0.000
H52.2 Astigmatism
0.614 0.386 0.000
R53 Malaise and fatigue
0.614 0.386 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.614 0.386 0.000
C80 Malignant neoplasm without specification of site
0.614 0.386 0.000
G60 Hereditary and idiopathic neuropathy
0.614 0.386 0.000
S98 Traumatic amputation of ankle and foot
0.614 0.386 0.000
S97 Crushing injury of ankle and foot
0.614 0.386 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.614 0.386 0.000
S95 Injury of blood vessels at ankle and foot level
0.614 0.386 0.000
S94 Injury of nerves at ankle and foot level
0.614 0.386 0.000
Y42.5 Other oestrogens and progestogens
0.614 0.386 0.000
H50.0 Convergent concomitant strabismus
0.613 0.387 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.612 0.388 0.000
Y98 Lifestyle-related condition
0.612 0.388 0.000
Y97 Environmental-pollution-related condition
0.612 0.388 0.000
Y96 Work-related condition
0.612 0.388 0.000
F80-F89 Disorders of psychological development
0.612 0.388 0.000
T42.4 Benzodiazepines
0.611 0.389 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.611 0.389 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.611 0.389 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.610 0.389 0.000
C22.7 Other specified carcinomas of liver
0.610 0.389 0.000
C22.4 Other sarcomas of liver
0.610 0.389 0.000
C22.3 Angiosarcoma of liver
0.610 0.389 0.000
C22.2 Hepatoblastoma
0.610 0.389 0.000
J09-J18 Influenza and pneumonia
0.610 0.390 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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