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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72875818
log Bayes Factor = 15.9254
Chromosome 6   position 62,043,183  (GRCh37) Explore rs72875818 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
Z92 Personal history of medical treatment
0.992 0.008 0.000
O60-O75 Complications of labour and delivery
0.991 0.009 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.990 0.010 0.000
I20 Angina pectoris
0.988 0.012 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.986 0.014 0.000
Chapter II Neoplasms
0.985 0.015 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.984 0.016 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.979 0.021 0.000
I71 Aortic aneurysm and dissection
0.970 0.030 0.000
I20.0 Unstable angina
0.967 0.033 0.000
I51 Complications and ill-defined descriptions of heart disease
0.962 0.038 0.000
C50-C50 Malignant neoplasm of breast
0.960 0.040 0.000
Z80 Family history of malignant neoplasm
0.959 0.041 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.956 0.044 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.949 0.051 0.000
Z80.3 Family history of malignant neoplasm of breast
0.943 0.057 0.000
C50 Malignant neoplasm of breast
0.943 0.057 0.000
I51.7 Cardiomegaly
0.941 0.059 0.000
S60-S69 Injuries to the wrist and hand
0.937 0.063 0.000
I46 Cardiac arrest
0.934 0.066 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.934 0.066 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.934 0.066 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.932 0.068 0.000
I35 Nonrheumatic aortic valve disorders
0.932 0.068 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.922 0.078 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.921 0.079 0.000
O36 Maternal care for other known or suspected foetal problems
0.916 0.084 0.000
O00-O08 Pregnancy with abortive outcome
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
F30-F39 Mood [affective] disorders
0.906 0.094 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.905 0.095 0.000
I20.9 Angina pectoris, unspecified
0.900 0.100 0.000
M80-M85 Disorders of bone density and structure
0.899 0.101 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.895 0.105 0.000
C50.1 Central portion of breast
0.893 0.107 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.893 0.107 0.000
I46.0 Cardiac arrest with successful resuscitation
0.886 0.114 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.885 0.115 0.000
O70 Perineal laceration during delivery
0.878 0.122 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.878 0.122 0.000
Chapter VIII Diseases of the ear and mastoid process
0.876 0.124 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.874 0.126 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.872 0.128 0.000
I25.2 Old myocardial infarction
0.871 0.129 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.869 0.131 0.000
O73 Retained placenta and membranes, without haemorrhage
0.869 0.131 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.867 0.133 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.864 0.136 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.861 0.139 0.000
Z95.1 Presence of aortocoronary bypass graft
0.860 0.140 0.000
I72 Other aneurysm
0.858 0.142 0.000
Z92.0 Personal history of contraception
0.853 0.147 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.853 0.147 0.000
O80-O84 Delivery
0.852 0.148 0.000
C50.2 Upper-inner quadrant of breast
0.850 0.150 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.849 0.151 0.000
O36.5 Maternal care for poor foetal growth
0.847 0.153 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.847 0.153 0.000
F40 Phobic anxiety disorders
0.846 0.154 0.000
I21 Acute myocardial infarction
0.846 0.154 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.845 0.155 0.000
W20-W49 Exposure to inanimate mechanical forces
0.841 0.159 0.000
I05-I09 Chronic rheumatic heart diseases
0.839 0.161 0.000
Z99.3 Dependence on wheelchair
0.837 0.162 0.000
T81 Complications of procedures, not elsewhere classified
0.836 0.164 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.833 0.167 0.000
O70.0 First degree perineal laceration during delivery
0.832 0.168 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.831 0.169 0.000
M81 Osteoporosis without pathological fracture
0.830 0.170 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.829 0.171 0.000
Z99.1 Dependence on respirator
0.825 0.175 0.000
O72 Postpartum haemorrhage
0.825 0.175 0.000
F32 Depressive episode
0.819 0.181 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.819 0.181 0.000
C79 Secondary malignant neoplasm of other sites
0.818 0.182 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.816 0.184 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.815 0.185 0.000
Z36 Antenatal screening
0.814 0.186 0.000
O03 Spontaneous abortion
0.814 0.186 0.000
O02 Other abnormal products of conception
0.814 0.186 0.000
F60-F69 Disorders of adult personality and behaviour
0.812 0.188 0.000
O41 Other disorders of amniotic fluid and membranes
0.811 0.189 0.000
Z37 Outcome of delivery
0.811 0.189 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.810 0.189 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.809 0.191 0.000
C77.4 Inguinal and lower limb lymph nodes
0.807 0.193 0.000
H65-H75 Diseases of middle ear and mastoid
0.807 0.193 0.000
F80-F89 Disorders of psychological development
0.806 0.194 0.000
I78 Diseases of capillaries
0.805 0.195 0.000
O61 Failed induction of labour
0.803 0.197 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.801 0.199 0.000
T66-T78 Other and unspecified effects of external causes
0.800 0.200 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.800 0.200 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.799 0.201 0.000
I60-I69 Cerebrovascular diseases
0.798 0.202 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.796 0.204 0.000
Z99.2 Dependence on renal dialysis
0.796 0.204 0.000
O23 Infections of genito-urinary tract in pregnancy
0.794 0.206 0.000
O36.8 Maternal care for other specified foetal problems
0.792 0.208 0.000
F40.2 Specific (isolated) phobias
0.792 0.208 0.000
I34 Nonrheumatic mitral valve disorders
0.791 0.209 0.000
C51-C58 Malignant neoplasms of female genital organs
0.791 0.209 0.000
S20-S29 Injuries to the thorax
0.790 0.210 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.790 0.210 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.790 0.210 0.000
O43 Placental disorders
0.790 0.210 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.788 0.212 0.000
I35.1 Aortic (valve) insufficiency
0.787 0.213 0.000
M85 Other disorders of bone density and structure
0.787 0.213 0.000
D45 Polycythaemia vera
0.786 0.214 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
S50-S59 Injuries to the elbow and forearm
0.783 0.217 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.782 0.218 0.000
Y52 Agents primarily affecting the cardiovascular system
0.782 0.218 0.000
O73.0 Retained placenta, without haemorrhage
0.782 0.218 0.000
Z89 Acquired absence of limb
0.780 0.220 0.000
F99-F99 Unspecified mental disorder
0.779 0.221 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.778 0.222 0.000
M05-M14 Inflammatory polyarthropathies
0.777 0.223 0.000
S60 Superficial injury of wrist and hand
0.776 0.224 0.000
Z94 Transplanted organ and tissue status
0.776 0.224 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.775 0.225 0.000
Z80.6 Family history of leukaemia
0.775 0.225 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.774 0.226 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.774 0.226 0.000
X20-X29 Contact with venomous animals and plants
0.774 0.226 0.000
O80 Single spontaneous delivery
0.774 0.226 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.773 0.227 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.773 0.227 0.000
Z81 Family history of mental and behavioural disorders
0.772 0.228 0.000
O42 Premature rupture of membranes
0.769 0.231 0.000
C43 Malignant melanoma of skin
0.768 0.232 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.767 0.233 0.000
V10-V19 Pedal cyclist injured in transport accident
0.766 0.234 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
C50.5 Lower-outer quadrant of breast
0.765 0.235 0.000
F41 Other anxiety disorders
0.765 0.235 0.000
I45 Other conduction disorders
0.763 0.237 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.762 0.238 0.000
I74 Arterial embolism and thrombosis
0.762 0.238 0.000
M81.9 Osteoporosis, unspecified
0.762 0.238 0.000
I42 Cardiomyopathy
0.756 0.244 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.755 0.245 0.000
X60-X84 Intentional self-harm
0.755 0.245 0.000
M65-M68 Disorders of synovium and tendon
0.754 0.246 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.753 0.247 0.000
I35.0 Aortic (valve) stenosis
0.753 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.752 0.248 0.000
Y44 Agents primarily affecting blood constituents
0.751 0.249 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.750 0.250 0.000
O46.9 Antepartum haemorrhage, unspecified
0.749 0.251 0.000
C80 Malignant neoplasm without specification of site
0.749 0.251 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.748 0.252 0.000
S64 Injury of nerves at wrist and hand level
0.747 0.253 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.746 0.254 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.745 0.255 0.000
Z75 Problems related to medical facilities and other health care
0.744 0.256 0.000
Z37.0 Single live birth
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
Z92.8 Personal history of other medical treatment
0.742 0.258 0.000
O40 Polyhydramnios
0.742 0.258 0.000
S62 Fracture at wrist and hand level
0.739 0.260 0.000
O16 Unspecified maternal hypertension
0.739 0.261 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.738 0.262 0.000
Chapter XXII Codes for special purposes
0.737 0.263 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.737 0.263 0.000
I51.9 Heart disease, unspecified
0.733 0.267 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.732 0.267 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.731 0.269 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.730 0.270 0.000
C50.9 Breast, unspecified
0.730 0.270 0.000
Z83 Family history of other specific disorders
0.729 0.271 0.000
F33 Recurrent depressive disorder
0.729 0.271 0.000
O02.1 Missed abortion
0.729 0.271 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.728 0.272 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.728 0.272 0.000
C77.1 Intrathoracic lymph nodes
0.727 0.273 0.000
Z95.3 Presence of xenogenic heart valve
0.725 0.275 0.000
I20.1 Angina pectoris with documented spasm
0.725 0.275 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.721 0.278 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.721 0.279 0.000
S61 Open wound of wrist and hand
0.721 0.279 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.720 0.280 0.000
I22 Subsequent myocardial infarction
0.720 0.280 0.000
Z98 Other postsurgical states
0.719 0.281 0.000
Z36.8 Other antenatal screening
0.719 0.281 0.000
I10-I15 Hypertensive diseases
0.718 0.282 0.000
M84 Disorders of continuity of bone
0.718 0.282 0.000
W00-W19 Falls
0.718 0.282 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.715 0.285 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
M80 Osteoporosis with pathological fracture
0.712 0.288 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.712 0.288 0.000
Z92.9 Personal history of medical treatment, unspecified
0.711 0.289 0.000
Z92.5 Personal history of rehabilitation measures
0.711 0.289 0.000
I31 Other diseases of pericardium
0.711 0.289 0.000
O74 Complications of anaesthesia during labour and delivery
0.711 0.289 0.000
O71 Other obstetric trauma
0.711 0.289 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.711 0.289 0.000
O66 Other obstructed labour
0.711 0.289 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.711 0.289 0.000
O60 Preterm delivery
0.711 0.289 0.000
O63 Long labour
0.710 0.289 0.000
T51 Toxic effect of alcohol
0.710 0.290 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.709 0.291 0.000
I50 Heart failure
0.709 0.291 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.708 0.292 0.000
O26.9 Pregnancy-related condition, unspecified
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.707 0.293 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
I25.5 Ischaemic cardiomyopathy
0.706 0.294 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.705 0.295 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.705 0.295 0.000
O21 Excessive vomiting in pregnancy
0.705 0.295 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.705 0.295 0.000
D69 Purpura and other haemorrhagic conditions
0.704 0.296 0.000
C77.5 Intrapelvic lymph nodes
0.704 0.296 0.000
O72.1 Other immediate postpartum haemorrhage
0.704 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.703 0.296 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.296 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.703 0.297 0.000
O45 Premature separation of placenta [abruptio placentae]
0.702 0.298 0.000
O44 Placenta praevia
0.702 0.298 0.000
O33 Maternal care for known or suspected disproportion
0.702 0.298 0.000
O31 Complications specific to multiple gestation
0.702 0.298 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.701 0.299 0.000
I70 Atherosclerosis
0.699 0.301 0.000
T81.9 Unspecified complication of procedure
0.699 0.301 0.000
I46.9 Cardiac arrest, unspecified
0.696 0.303 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.696 0.304 0.000
Z33 Pregnant state, incidental
0.696 0.304 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.696 0.304 0.000
F32.1 Moderate depressive episode
0.696 0.304 0.000
O80.0 Spontaneous vertex delivery
0.696 0.304 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.695 0.304 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.695 0.304 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.695 0.304 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.695 0.304 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.695 0.304 0.000
I71.0 Dissection of aorta [any part]
0.695 0.304 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.693 0.307 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.308 0.000
O03.9 Complete or unspecified, without complication
0.691 0.308 0.000
I08 Multiple valve diseases
0.691 0.309 0.000
I72.4 Aneurysm of artery of lower extremity
0.691 0.309 0.000
Q50-Q56 Congenital malformations of genital organs
0.690 0.309 0.000
O41.0 Oligohydramnios
0.690 0.310 0.000
M91-M94 Chondropathies
0.690 0.310 0.000
I51.6 Cardiovascular disease, unspecified
0.690 0.310 0.000
I51.5 Myocardial degeneration
0.690 0.310 0.000
I51.4 Myocarditis, unspecified
0.690 0.310 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.690 0.310 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.690 0.310 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.690 0.310 0.000
I51.0 Cardiac septal defect, acquired
0.690 0.310 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
F32.8 Other depressive episodes
0.689 0.311 0.000
I38 Endocarditis, valve unspecified
0.688 0.312 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.688 0.312 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.688 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.687 0.313 0.000
I72.3 Aneurysm of iliac artery
0.686 0.314 0.000
I35.9 Aortic valve disorder, unspecified
0.686 0.314 0.000
C45 Mesothelioma
0.686 0.314 0.000
O26.8 Other specified pregnancy-related conditions
0.685 0.315 0.000
O62 Abnormalities of forces of labour
0.685 0.315 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.685 0.315 0.000
M81.98 Osteoporosis, unspecified (Other)
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.316 0.000
T31 Burns classified according to extent of body surface involved
0.683 0.317 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.683 0.317 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.683 0.317 0.000
Q23 Congenital malformations of aortic and mitral valves
0.683 0.317 0.000
O30 Multiple gestation
0.682 0.317 0.000
F60 Specific personality disorders
0.682 0.318 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.682 0.318 0.000
W29 Contact with other powered hand tools and household machinery
0.681 0.319 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.681 0.319 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.681 0.319 0.000
Z99.4 Dependence on artificial heart
0.681 0.319 0.000
Z99.0 Dependence on aspirator
0.681 0.319 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.680 0.320 0.000
O03.4 Incomplete, without complication
0.680 0.320 0.000
Z95.4 Presence of other heart-valve replacement
0.679 0.321 0.000
O47 False labour
0.678 0.322 0.000
H74 Other disorders of middle ear and mastoid
0.678 0.322 0.000
M85.8 Other specified disorders of bone density and structure
0.677 0.323 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.677 0.323 0.000
Y43 Primarily systemic agents
0.677 0.323 0.000
C50.6 Axillary tail of breast
0.676 0.324 0.000
C50.0 Nipple and areola
0.676 0.324 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.675 0.324 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.675 0.325 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.674 0.326 0.000
I63 Cerebral infarction
0.674 0.326 0.000
T82.3 Mechanical complication of other vascular grafts
0.673 0.327 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.673 0.327 0.000
Z32 Pregnancy examination and test
0.672 0.328 0.000
S67 Crushing injury of wrist and hand
0.672 0.328 0.000
S65 Injury of blood vessels at wrist and hand level
0.672 0.328 0.000
M45-M49 Spondylopathies
0.671 0.329 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.671 0.329 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.671 0.329 0.000
F81 Specific developmental disorders of scholastic skills
0.671 0.329 0.000
M86-M90 Other osteopathies
0.670 0.329 0.000
I49 Other cardiac arrhythmias
0.670 0.329 0.000
I05 Rheumatic mitral valve diseases
0.670 0.330 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.670 0.330 0.000
I46.1 Sudden cardiac death, so described
0.670 0.330 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.670 0.330 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.670 0.330 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.670 0.330 0.000
T83.2 Mechanical complication of graft of urinary organ
0.670 0.330 0.000
D69.6 Thrombocytopenia, unspecified
0.670 0.330 0.000
I72.8 Aneurysm of other specified arteries
0.670 0.330 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.669 0.331 0.000
O61.0 Failed medical induction of labour
0.668 0.332 0.000
Z36.9 Antenatal screening, unspecified
0.668 0.332 0.000
O29 Complications of anaesthesia during pregnancy
0.668 0.332 0.000
O28 Abnormal findings on antenatal screening of mother
0.668 0.332 0.000
O24 Diabetes mellitus in pregnancy
0.668 0.332 0.000
O22 Venous complications in pregnancy
0.668 0.332 0.000
O25 Malnutrition in pregnancy
0.668 0.332 0.000
I35.8 Other aortic valve disorders
0.668 0.332 0.000
Q24 Other congenital malformations of heart
0.667 0.333 0.000
I33 Acute and subacute endocarditis
0.667 0.333 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.666 0.334 0.000
F43 Reaction to severe stress, and adjustment disorders
0.666 0.334 0.000
S69 Other and unspecified injuries of wrist and hand
0.666 0.334 0.000
T59 Toxic effect of other gases, fumes and vapours
0.665 0.335 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.664 0.336 0.000
O70.2 Third degree perineal laceration during delivery
0.664 0.336 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.664 0.336 0.000
Z31 Procreative management
0.664 0.336 0.000
O75.0 Maternal distress during labour and delivery
0.662 0.337 0.000
H72 Perforation of tympanic membrane
0.662 0.338 0.000
F48 Other neurotic disorders
0.661 0.339 0.000
F44 Dissociative [conversion] disorders
0.661 0.339 0.000
F42 Obsessive-compulsive disorder
0.661 0.339 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.661 0.339 0.000
M60-M63 Disorders of muscles
0.660 0.339 0.000
M00-M03 Infectious arthropathies
0.660 0.339 0.000
Q60-Q64 Congenital malformations of the urinary system
0.660 0.340 0.000
M81.4 Drug-induced osteoporosis
0.660 0.340 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.660 0.340 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.659 0.341 0.000
H80-H83 Diseases of inner ear
0.659 0.341 0.000
Z95.2 Presence of prosthetic heart valve
0.659 0.341 0.000
F10.1 Harmful use
0.659 0.341 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.658 0.342 0.000
Y57 Other and unspecified drugs and medicaments
0.658 0.342 0.000
T78 Adverse effects, not elsewhere classified
0.658 0.342 0.000
O36.9 Maternal care for foetal problem, unspecified
0.657 0.343 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.657 0.343 0.000
O36.6 Maternal care for excessive foetal growth
0.657 0.343 0.000
O36.4 Maternal care for intra-uterine death
0.657 0.343 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.657 0.343 0.000
O36.2 Maternal care for hydrops foetalis
0.657 0.343 0.000
O36.1 Maternal care for other isoimmunisation
0.657 0.343 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.656 0.344 0.000
C50.8 Overlapping lesion of breast
0.656 0.344 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.656 0.344 0.000
O23.5 Infections of the genital tract in pregnancy
0.656 0.344 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.656 0.344 0.000
Z94.0 Kidney transplant status
0.655 0.345 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.655 0.345 0.000
O07 Failed attempted abortion
0.655 0.345 0.000
O06 Unspecified abortion
0.655 0.345 0.000
O05 Other abortion
0.655 0.345 0.000
O01 Hydatidiform mole
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.654 0.345 0.000
Q80-Q89 Other congenital malformations
0.654 0.345 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.654 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.654 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.654 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.654 0.345 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.345 0.000
O20 Haemorrhage in early pregnancy
0.654 0.346 0.000
O43.8 Other placental disorders
0.654 0.346 0.000
D00-D09 In situ neoplasms
0.654 0.346 0.000
Y83.6 Removal of other organ (partial) (total)
0.654 0.346 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.654 0.346 0.000
Z35 Supervision of high-risk pregnancy
0.652 0.348 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.651 0.349 0.000
C50.3 Lower-inner quadrant of breast
0.651 0.349 0.000
C77.9 Lymph node, unspecified
0.650 0.350 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.650 0.350 0.000
S68 Traumatic amputation of wrist and hand
0.650 0.350 0.000
F38 Other mood [affective] disorders
0.649 0.350 0.000
F34 Persistent mood [affective] disorders
0.649 0.350 0.000
F30 Manic episode
0.649 0.350 0.000
F39 Unspecified mood [affective] disorder
0.649 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.649 0.351 0.000
Y58 Bacterial vaccines
0.649 0.351 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.649 0.351 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.649 0.351 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.649 0.351 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.649 0.351 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
Y48 Anaesthetics and therapeutic gases
0.649 0.351 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.649 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.649 0.351 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.649 0.351 0.000
C77.3 Axillary and upper limb lymph nodes
0.647 0.353 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.647 0.353 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.647 0.353 0.000
M83 Adult osteomalacia
0.645 0.355 0.000
M82 Osteoporosis in diseases classified elsewhere
0.645 0.355 0.000
I12 Hypertensive renal disease
0.645 0.355 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.644 0.356 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.644 0.356 0.000
I24 Other acute ischaemic heart diseases
0.644 0.356 0.000
O75.8 Other specified complications of labour and delivery
0.642 0.358 0.000
Z38 Liveborn infants according to place of birth
0.642 0.358 0.000
S52 Fracture of forearm
0.641 0.359 0.000
Y44.2 Anticoagulants
0.641 0.359 0.000
M65 Synovitis and tenosynovitis
0.640 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.640 0.360 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.638 0.362 0.000
C77.8 Lymph nodes of multiple regions
0.638 0.362 0.000
I45.6 Preexcitation syndrome
0.638 0.362 0.000
Z29 Need for other prophylactic measures
0.637 0.363 0.000
C50.4 Upper-outer quadrant of breast
0.637 0.363 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.637 0.363 0.000
S29 Other and unspecified injuries of thorax
0.635 0.365 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.634 0.365 0.000
Z74 Problems related to care-provider dependency
0.633 0.366 0.000
F31 Bipolar affective disorder
0.632 0.368 0.000
M40-M43 Deforming dorsopathies
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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