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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72878203
log Bayes Factor = 10.9744
Chromosome 11   position 29,074,632  (GRCh37) Explore rs72878203 on Ensembl!
Variant rs72878203 is part of Cluster X0193

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
S80-S89 Injuries to the knee and lower leg
0.992 0.008 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
N17-N19 Renal failure
0.989 0.011 0.000
N18 Chronic renal failure
0.988 0.012 0.000
S00-S09 Injuries to the head
0.985 0.015 0.000
R50-R69 General symptoms and signs
0.981 0.019 0.000
N18.9 Chronic renal failure, unspecified
0.981 0.019 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.978 0.022 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.977 0.023 0.000
R06 Abnormalities of breathing
0.971 0.029 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.965 0.035 0.000
M48 Other spondylopathies
0.961 0.039 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.959 0.041 0.000
S09 Other and unspecified injuries of head
0.956 0.044 0.000
R47-R49 Symptoms and signs involving speech and voice
0.955 0.045 0.000
Chapter VI Diseases of the nervous system
0.955 0.045 0.000
R51 Headache
0.954 0.046 0.000
R26 Abnormalities of gait and mobility
0.951 0.049 0.000
M48.0 Spinal stenosis
0.949 0.051 0.000
R06.8 Other and unspecified abnormalities of breathing
0.940 0.060 0.000
Chapter VIII Diseases of the ear and mastoid process
0.940 0.060 0.000
N30-N39 Other diseases of urinary system
0.932 0.068 0.000
S09.9 Unspecified injury of head
0.932 0.068 0.000
R47 Speech disturbances, not elsewhere classified
0.931 0.069 0.000
M48.06 Spinal stenosis (Lumbar region)
0.930 0.070 0.000
N17 Acute renal failure
0.926 0.074 0.000
M40-M43 Deforming dorsopathies
0.923 0.077 0.000
R63 Symptoms and signs concerning food and fluid intake
0.922 0.078 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.922 0.078 0.000
N18.3 Chronic kidney disease, stage 3
0.921 0.079 0.000
S82 Fracture of lower leg, including ankle
0.921 0.079 0.000
S80 Superficial injury of lower leg
0.919 0.081 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.917 0.083 0.000
R47.8 Other and unspecified speech disturbances
0.914 0.086 0.000
T79-T79 Certain early complications of trauma
0.914 0.086 0.000
Chapter V Mental and behavioural disorders
0.908 0.092 0.000
M65-M68 Disorders of synovium and tendon
0.902 0.098 0.000
G20-G26 Extrapyramidal and movement disorders
0.900 0.100 0.000
R21 Rash and other nonspecific skin eruption
0.896 0.104 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.896 0.104 0.000
S05 Injury of eye and orbit
0.894 0.106 0.000
R60 Oedema, not elsewhere classified
0.892 0.108 0.000
T93 Sequelae of injuries of lower limb
0.889 0.111 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.884 0.116 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.882 0.118 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.874 0.126 0.000
T90 Sequelae of injuries of head
0.870 0.130 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.865 0.135 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.862 0.138 0.000
R06.0 Dyspnoea
0.859 0.141 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.858 0.142 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.858 0.142 0.000
M48.09 Spinal stenosis (Site unspecified)
0.858 0.142 0.000
S90-S99 Injuries to the ankle and foot
0.854 0.145 0.000
Chapter XX External causes of morbidity and mortality
0.854 0.146 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.852 0.148 0.000
M65 Synovitis and tenosynovitis
0.851 0.149 0.000
G90-G99 Other disorders of the nervous system
0.848 0.152 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.847 0.153 0.000
M47 Spondylosis
0.846 0.154 0.000
G40-G47 Episodic and paroxysmal disorders
0.841 0.159 0.000
N17.9 Acute renal failure, unspecified
0.837 0.163 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.831 0.169 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.830 0.170 0.000
H60-H62 Diseases of external ear
0.828 0.172 0.000
R61 Hyperhidrosis
0.828 0.172 0.000
R64 Cachexia
0.827 0.173 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.827 0.173 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.825 0.175 0.000
M50-M54 Other dorsopathies
0.822 0.178 0.000
R60.9 Oedema, unspecified
0.819 0.181 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.819 0.181 0.000
H65-H75 Diseases of middle ear and mastoid
0.817 0.183 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.817 0.183 0.000
M00-M03 Infectious arthropathies
0.817 0.183 0.000
M43 Other deforming dorsopathies
0.817 0.183 0.000
N30 Cystitis
0.816 0.184 0.000
S82.3 Fracture of lower end of tibia
0.814 0.186 0.000
S50-S59 Injuries to the elbow and forearm
0.814 0.186 0.000
S80.0 Contusion of knee
0.813 0.187 0.000
S83.2 Tear of meniscus, current
0.813 0.187 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.812 0.188 0.000
R04 Haemorrhage from respiratory passages
0.808 0.191 0.000
G43 Migraine
0.808 0.192 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
T93.1 Sequelae of fracture of femur
0.805 0.195 0.000
G24 Dystonia
0.804 0.196 0.000
N18.8 Other chronic renal failure
0.802 0.198 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.802 0.198 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
M80-M85 Disorders of bone density and structure
0.801 0.199 0.000
S86 Injury of muscle and tendon at lower leg level
0.800 0.200 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.799 0.201 0.000
G20 Parkinson's disease
0.799 0.201 0.000
R63.0 Anorexia
0.797 0.203 0.000
M05-M14 Inflammatory polyarthropathies
0.796 0.204 0.000
S00 Superficial injury of head
0.795 0.205 0.000
N17.0 Acute renal failure with tubular necrosis
0.795 0.205 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.793 0.207 0.000
H90-H95 Other disorders of ear
0.791 0.209 0.000
M41 Scoliosis
0.789 0.211 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.788 0.212 0.000
R69 Unknown and unspecified causes of morbidity
0.788 0.212 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.788 0.212 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.787 0.213 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.784 0.216 0.000
M65.3 Trigger finger
0.783 0.217 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.783 0.217 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.783 0.217 0.000
M91-M94 Chondropathies
0.782 0.218 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.782 0.218 0.000
S82.2 Fracture of shaft of tibia
0.781 0.219 0.000
R23 Other skin changes
0.780 0.220 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.778 0.221 0.000
N18.2 Chronic kidney disease, stage 2
0.778 0.222 0.000
H60 Otitis externa
0.777 0.223 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.777 0.223 0.000
R06.4 Hyperventilation
0.776 0.224 0.000
G43.9 Migraine, unspecified
0.775 0.225 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.775 0.225 0.000
W00-W19 Falls
0.774 0.226 0.000
R52 Pain, not elsewhere classified
0.773 0.227 0.000
G70-G73 Diseases of myoneural junction and muscle
0.772 0.228 0.000
R25 Abnormal involuntary movements
0.772 0.228 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.771 0.229 0.000
R19.4 Change in bowel habit
0.770 0.230 0.000
R63.1 Polydipsia
0.770 0.230 0.000
R04.2 Haemoptysis
0.770 0.230 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.769 0.231 0.000
S80.8 Other superficial injuries of lower leg
0.768 0.232 0.000
R06.1 Stridor
0.767 0.233 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.767 0.233 0.000
T93.2 Sequelae of other fractures of lower limb
0.767 0.233 0.000
S82.4 Fracture of fibula alone
0.766 0.234 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.766 0.234 0.000
T51 Toxic effect of alcohol
0.763 0.237 0.000
Chapter XXII Codes for special purposes
0.762 0.238 0.000
M60-M63 Disorders of muscles
0.761 0.239 0.000
E20-E35 Disorders of other endocrine glands
0.760 0.240 0.000
R26.0 Ataxic gait
0.758 0.242 0.000
N00-N08 Glomerular diseases
0.758 0.242 0.000
G90 Disorders of autonomic nervous system
0.756 0.244 0.000
S05.1 Contusion of eyeball and orbital tissues
0.756 0.244 0.000
R26.3 Immobility
0.754 0.245 0.000
S82.6 Fracture of lateral malleolus
0.754 0.246 0.000
N36 Other disorders of urethra
0.753 0.247 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.751 0.249 0.000
S81 Open wound of lower leg
0.751 0.249 0.000
S02 Fracture of skull and facial bones
0.744 0.256 0.000
R00 Abnormalities of heart beat
0.744 0.256 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.744 0.256 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.742 0.258 0.000
M43.1 Spondylolisthesis
0.741 0.259 0.000
S92 Fracture of foot, except ankle
0.740 0.260 0.000
N40-N51 Diseases of male genital organs
0.740 0.260 0.000
R06.6 Hiccough
0.739 0.261 0.000
M20-M25 Other joint disorders
0.736 0.264 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.736 0.264 0.000
R06.5 Mouth breathing
0.736 0.264 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.735 0.265 0.000
N18.4 Chronic kidney disease, stage 4
0.735 0.265 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.735 0.265 0.000
M65.34 Trigger finger-Hand
0.735 0.265 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.734 0.266 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.733 0.267 0.000
N18.5 Chronic kidney disease, stage 5
0.732 0.268 0.000
R27 Other lack of coordination
0.732 0.268 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.732 0.268 0.000
R82 Other abnormal findings in urine
0.731 0.269 0.000
R06.2 Wheezing
0.726 0.274 0.000
F25 Schizoaffective disorders
0.725 0.275 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.722 0.278 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.722 0.278 0.000
S09.8 Other specified injuries of head
0.721 0.279 0.000
N99-N99 Other disorders of the genitourinary system
0.721 0.279 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.719 0.281 0.000
R61.9 Hyperhidrosis, unspecified
0.719 0.281 0.000
S05.8 Other injuries of eye and orbit
0.718 0.282 0.000
T42.4 Benzodiazepines
0.718 0.282 0.000
M84 Disorders of continuity of bone
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
M50 Cervical disk disorders
0.715 0.285 0.000
M47.8 Other spondylosis
0.714 0.286 0.000
S88 Traumatic amputation of lower leg
0.711 0.289 0.000
S87 Crushing injury of lower leg
0.711 0.289 0.000
S85 Injury of blood vessels at lower leg level
0.711 0.289 0.000
S84 Injury of nerves at lower leg level
0.711 0.289 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.711 0.289 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.710 0.290 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.710 0.290 0.000
H90 Conductive and sensorineural hearing loss
0.710 0.290 0.000
N18.1 Chronic kidney disease, stage 1
0.709 0.291 0.000
T92 Sequelae of injuries of upper limb
0.709 0.291 0.000
S10-S19 Injuries to the neck
0.708 0.292 0.000
R58 Haemorrhage, not elsewhere classified
0.708 0.292 0.000
M86-M90 Other osteopathies
0.707 0.293 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
R57 Shock, not elsewhere classified
0.705 0.295 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.705 0.295 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.704 0.296 0.000
R62 Lack of expected normal physiological development
0.704 0.296 0.000
R02 Gangrene, not elsewhere classified
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.298 0.000
S82.31 Fracture of lower end of tibia (open)
0.701 0.299 0.000
Chapter I Certain infectious and parasitic diseases
0.701 0.299 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.701 0.299 0.000
N30.2 Other chronic cystitis
0.700 0.300 0.000
R81 Glycosuria
0.699 0.301 0.000
N34 Urethritis and urethral syndrome
0.698 0.302 0.000
M25 Other joint disorders, not elsewhere classified
0.697 0.303 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
R06.7 Sneezing
0.696 0.304 0.000
R06.3 Periodic breathing
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.694 0.305 0.000
F30-F39 Mood [affective] disorders
0.694 0.306 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
R53 Malaise and fatigue
0.693 0.307 0.000
R47.0 Dysphasia and aphasia
0.693 0.307 0.000
M41.9 Scoliosis, unspecified
0.693 0.307 0.000
R74 Abnormal serum enzyme levels
0.692 0.308 0.000
T98 Sequelae of other and unspecified effects of external causes
0.692 0.308 0.000
T95 Sequelae of burns, corrosions and frostbite
0.692 0.308 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.692 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.692 0.308 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.692 0.308 0.000
S32 Fracture of lumbar spine and pelvis
0.692 0.308 0.000
R60.1 Generalised oedema
0.691 0.309 0.000
M48.9 Spondylopathy, unspecified
0.689 0.311 0.000
M48.8 Other specified spondylopathies
0.689 0.311 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.689 0.311 0.000
M48.4 Fatigue fracture of vertebra
0.689 0.311 0.000
M48.3 Traumatic spondylopathy
0.689 0.311 0.000
M48.2 Kissing spine
0.689 0.311 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.689 0.311 0.000
F80-F89 Disorders of psychological development
0.689 0.311 0.000
T51.0 Ethanol
0.688 0.311 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.688 0.312 0.000
G93 Other disorders of brain
0.688 0.312 0.000
S80.9 Superficial injury of lower leg, unspecified
0.686 0.314 0.000
M00 Pyogenic arthritis
0.686 0.314 0.000
R52.1 Chronic intractable pain
0.686 0.314 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.686 0.314 0.000
R68 Other general symptoms and signs
0.686 0.314 0.000
T79.8 Other early complications of trauma
0.686 0.314 0.000
S09.7 Multiple injuries of head
0.685 0.315 0.000
S09.2 Traumatic rupture of ear drum
0.685 0.315 0.000
S09.1 Injury of muscle and tendon of head
0.685 0.315 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.685 0.315 0.000
H71 Cholesteatoma of middle ear
0.685 0.315 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.685 0.315 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.682 0.318 0.000
R26.1 Paralytic gait
0.681 0.318 0.000
G24.8 Other dystonia
0.680 0.320 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.680 0.320 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.680 0.320 0.000
M48.04 Spinal stenosis (Thoracic region)
0.680 0.320 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.680 0.320 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.680 0.320 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.680 0.320 0.000
N36.0 Urethral fistula
0.679 0.321 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.678 0.322 0.000
R79 Other abnormal findings of blood chemistry
0.678 0.322 0.000
S82.5 Fracture of medial malleolus
0.677 0.323 0.000
N50 Other disorders of male genital organs
0.677 0.323 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.676 0.324 0.000
R71 Abnormality of red blood cells
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.674 0.326 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.673 0.327 0.000
N30.0 Acute cystitis
0.673 0.327 0.000
M65.1 Other infective (teno)synovitis
0.671 0.329 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.670 0.330 0.000
S50 Superficial injury of forearm
0.669 0.331 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.669 0.331 0.000
N37 Urethral disorders in diseases classified elsewhere
0.668 0.332 0.000
N33 Bladder disorders in diseases classified elsewhere
0.668 0.332 0.000
E29 Testicular dysfunction
0.668 0.332 0.000
R23.2 Flushing
0.668 0.332 0.000
M47.9 Spondylosis, unspecified
0.668 0.332 0.000
T90.5 Sequelae of intracranial injury
0.668 0.332 0.000
Q80-Q89 Other congenital malformations
0.667 0.333 0.000
W50-W64 Exposure to animate mechanical forces
0.667 0.333 0.000
S90 Superficial injury of ankle and foot
0.666 0.334 0.000
R00.0 Tachycardia, unspecified
0.666 0.334 0.000
H60.1 Cellulitis of external ear
0.666 0.334 0.000
M45 Ankylosing spondylitis
0.665 0.335 0.000
N17.8 Other acute renal failure
0.664 0.336 0.000
N17.2 Acute renal failure with medullary necrosis
0.664 0.336 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.664 0.336 0.000
Y57 Other and unspecified drugs and medicaments
0.664 0.336 0.000
G30-G32 Other degenerative diseases of the nervous system
0.663 0.337 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.663 0.337 0.000
F10.1 Harmful use
0.662 0.338 0.000
M50.1 Cervical disk disorder with radiculopathy
0.662 0.338 0.000
M42 Spinal osteochondrosis
0.661 0.338 0.000
M40 Kyphosis and lordosis
0.661 0.338 0.000
W20-W49 Exposure to inanimate mechanical forces
0.661 0.338 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.661 0.339 0.000
R63.5 Abnormal weight gain
0.661 0.339 0.000
R63.3 Feeding difficulties and mismanagement
0.661 0.339 0.000
R63.2 Polyphagia
0.661 0.339 0.000
E50-E64 Other nutritional deficiencies
0.661 0.339 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.661 0.339 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.661 0.339 0.000
S82.9 Fracture of lower leg, part unspecified
0.660 0.340 0.000
S82.7 Multiple fractures of lower leg
0.660 0.340 0.000
S82.30 Fracture of lower end of tibia (closed)
0.660 0.340 0.000
F22 Persistent delusional disorders
0.659 0.341 0.000
S80.7 Multiple superficial injuries of lower leg
0.659 0.341 0.000
G90.3 Multisystem degeneration
0.657 0.343 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.657 0.343 0.000
W19 Unspecified fall
0.657 0.343 0.000
S82.40 Fracture of fibula alone (closed)
0.656 0.344 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.654 0.346 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.654 0.346 0.000
S20-S29 Injuries to the thorax
0.654 0.346 0.000
S52 Fracture of forearm
0.653 0.347 0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level
0.653 0.347 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.653 0.347 0.000
H60.9 Otitis externa, unspecified
0.652 0.347 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.651 0.349 0.000
F70-F79 Mental retardation
0.651 0.349 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.651 0.349 0.000
G24.9 Dystonia, unspecified
0.651 0.349 0.000
H60.0 Abscess of external ear
0.650 0.349 0.000
R63.4 Abnormal weight loss
0.650 0.350 0.000
R29.6 Tendency to fall, not elsewhere classified
0.649 0.351 0.000
E23 Hypofunction and other disorders of pituitary gland
0.649 0.351 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.649 0.351 0.000
F99-F99 Unspecified mental disorder
0.648 0.352 0.000
S82.21 Fracture of shaft of tibia (open)
0.648 0.352 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.647 0.353 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.647 0.353 0.000
M66 Spontaneous rupture of synovium and tendon
0.647 0.353 0.000
R25.1 Tremor, unspecified
0.646 0.354 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.646 0.354 0.000
M25.4 Effusion of joint
0.646 0.354 0.000
G43.1 Migraine with aura [classical migraine]
0.645 0.355 0.000
G23 Other degenerative diseases of basal ganglia
0.645 0.355 0.000
G21 Secondary Parkinsonism
0.645 0.355 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.645 0.355 0.000
G22 Parkinsonism in diseases classified elsewhere
0.645 0.355 0.000
X60-X84 Intentional self-harm
0.644 0.356 0.000
S00.1 Contusion of eyelid and periocular area
0.644 0.356 0.000
N18.0 End-stage renal disease
0.644 0.356 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.642 0.358 0.000
T39.0 Salicylates
0.641 0.359 0.000
S05.9 Injury of eye and orbit, part unspecified
0.641 0.359 0.000
S05.7 Avulsion of eye
0.641 0.359 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.641 0.359 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.641 0.359 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.641 0.359 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.641 0.359 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.641 0.359 0.000
E24 Cushing's syndrome
0.641 0.359 0.000
S06 Intracranial injury
0.639 0.361 0.000
H65 Nonsuppurative otitis media
0.639 0.361 0.000
D69 Purpura and other haemorrhagic conditions
0.639 0.361 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.639 0.361 0.000
R41.0 Disorientation, unspecified
0.638 0.362 0.000
H69 Other disorders of Eustachian tube
0.638 0.362 0.000
T39.1 4-Aminophenol derivatives
0.638 0.362 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.637 0.362 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.637 0.362 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.637 0.362 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.637 0.362 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.637 0.362 0.000
T93.0 Sequelae of open wound of lower limb
0.637 0.362 0.000
N30.1 Interstitial cystitis (chronic)
0.637 0.363 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.636 0.364 0.000
X50-X57 Overexertion, travel and privation
0.636 0.364 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.636 0.364 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.636 0.364 0.000
G25 Other extrapyramidal and movement disorders
0.636 0.364 0.000
R47.1 Dysarthria and anarthria
0.635 0.365 0.000
S82.60 Fracture of lateral malleolus (closed)
0.635 0.365 0.000
F10.0 Acute intoxication
0.635 0.365 0.000
M07 Psoriatic and enteropathic arthropathies
0.634 0.366 0.000
S83.7 Injury to multiple structures of knee
0.634 0.366 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.634 0.366 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.634 0.366 0.000
S83.3 Tear of articular cartilage of knee, current
0.634 0.366 0.000
S83.1 Dislocation of knee
0.634 0.366 0.000
S83.0 Dislocation of patella
0.634 0.366 0.000
V80-V89 Other land transport accidents
0.633 0.367 0.000
M06 Other rheumatoid arthritis
0.633 0.367 0.000
T90.9 Sequelae of unspecified injury of head
0.632 0.368 0.000
S92.2 Fracture of other tarsal bone(s)
0.630 0.370 0.000
V40-V49 Car occupant injured in transport accident
0.630 0.370 0.000
G96 Other disorders of central nervous system
0.629 0.371 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.628 0.372 0.000
M92 Other juvenile osteochondrosis
0.628 0.372 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.627 0.373 0.000
R46 Symptoms and signs involving appearance and behaviour
0.627 0.373 0.000
R43 Disturbances of smell and taste
0.627 0.373 0.000
H72 Perforation of tympanic membrane
0.626 0.374 0.000
R42 Dizziness and giddiness
0.625 0.375 0.000
N05 Unspecified nephritic syndrome
0.625 0.375 0.000
S00.7 Multiple superficial injuries of head
0.625 0.375 0.000
T90.8 Sequelae of other specified injuries of head
0.623 0.376 0.000
T90.4 Sequelae of injury of eye and orbit
0.623 0.376 0.000
T90.3 Sequelae of injury of cranial nerves
0.623 0.376 0.000
T90.1 Sequelae of open wound of head
0.623 0.376 0.000
T90.0 Sequelae of superficial injury of head
0.623 0.376 0.000
G40 Epilepsy
0.623 0.377 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.623 0.377 0.000
N30.8 Other cystitis
0.622 0.378 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.621 0.379 0.000
G70 Myasthenia gravis and other myoneural disorders
0.621 0.379 0.000
T40.2 Other opioids
0.620 0.379 0.000
Y42.5 Other oestrogens and progestogens
0.619 0.381 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.619 0.381 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.619 0.381 0.000
G41 Status epilepticus
0.619 0.381 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.618 0.382 0.000
T65 Toxic effect of other and unspecified substances
0.618 0.382 0.000
T63 Toxic effect of contact with venomous animals
0.618 0.382 0.000
T62 Toxic effect of other noxious substances eaten as food
0.618 0.382 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.618 0.382 0.000
T60 Toxic effect of pesticides
0.618 0.382 0.000
T59 Toxic effect of other gases, fumes and vapours
0.618 0.382 0.000
T57 Toxic effect of other inorganic substances
0.618 0.382 0.000
T56 Toxic effect of metals
0.618 0.382 0.000
T54 Toxic effect of corrosive substances
0.618 0.382 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.618 0.382 0.000
T52 Toxic effect of organic solvents
0.618 0.382 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.618 0.382 0.000
T58 Toxic effect of carbon monoxide
0.618 0.382 0.000
T55 Toxic effect of soaps and detergents
0.618 0.382 0.000
R11 Nausea and vomiting
0.618 0.382 0.000
G24.5 Blepharospasm
0.617 0.382 0.000
F29 Unspecified nonorganic psychosis
0.617 0.383 0.000
M85 Other disorders of bone density and structure
0.617 0.383 0.000
M47.2 Other spondylosis with radiculopathy
0.617 0.383 0.000
S82.20 Fracture of shaft of tibia (closed)
0.616 0.383 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.616 0.384 0.000
N45 Orchitis and epididymitis
0.616 0.384 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.615 0.385 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.615 0.385 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.615 0.385 0.000
S37 Injury of urinary and pelvic organs
0.615 0.385 0.000
S36 Injury of intra-abdominal organs
0.615 0.385 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.615 0.385 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.615 0.385 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.615 0.385 0.000
S31 Open wound of abdomen, lower back and pelvis
0.615 0.385 0.000
N20-N23 Urolithiasis
0.615 0.385 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.614 0.386 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.614 0.386 0.000
G91 Hydrocephalus
0.614 0.386 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.613 0.387 0.000
S99 Other and unspecified injuries of ankle and foot
0.613 0.387 0.000
S98 Traumatic amputation of ankle and foot
0.613 0.387 0.000
S97 Crushing injury of ankle and foot
0.613 0.387 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.613 0.387 0.000
S95 Injury of blood vessels at ankle and foot level
0.613 0.387 0.000
S94 Injury of nerves at ankle and foot level
0.613 0.387 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.613 0.387 0.000
T45.0 Antiallergic and antiemetic drugs
0.612 0.387 0.000
Y35-Y36 Legal intervention and operations of war
0.612 0.387 0.000
Y10-Y34 Event of undetermined intent
0.612 0.387 0.000
Y00-Y09 Assault
0.612 0.387 0.000
X85-X99 Assault
0.612 0.387 0.000
X30-X39 Exposure to forces of nature
0.612 0.387 0.000
X20-X29 Contact with venomous animals and plants
0.612 0.387 0.000
X10-X19 Contact with heat and hot substances
0.612 0.387 0.000
X00-X09 Exposure to smoke, fire and flames
0.612 0.387 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.612 0.387 0.000
W75-W84 Other accidental threats to breathing
0.612 0.387 0.000
W65-W74 Accidental drowning and submersion
0.612 0.387 0.000
V98-V99 Other and unspecified transport accidents
0.612 0.387 0.000
V95-V97 Air and space transport accidents
0.612 0.387 0.000
V90-V94 Water transport accidents
0.612 0.387 0.000
V70-V79 Bus occupant injured in transport accident
0.612 0.387 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.612 0.387 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.612 0.387 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.612 0.387 0.000
V01-V09 Pedestrian injured in transport accident
0.612 0.387 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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