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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72880536
log Bayes Factor = 13.1874
Chromosome 6   position 33,752,386  (GRCh37) Explore rs72880536 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
M05 Seropositive rheumatoid arthritis
0.988 0.012 0.000
Chapter VII Diseases of the eye and adnexa
0.986 0.014 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.980 0.020 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.980 0.020 0.000
E11 Non-insulin-dependent diabetes mellitus
0.980 0.020 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
M70-M79 Other soft tissue disorders
0.977 0.023 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.974 0.026 0.000
D50-D53 Nutritional anaemias
0.974 0.026 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.970 0.030 0.000
D50 Iron deficiency anaemia
0.968 0.032 0.000
E10.3 With ophthalmic complications
0.968 0.032 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.965 0.035 0.000
Chapter I Certain infectious and parasitic diseases
0.959 0.041 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.957 0.043 0.000
E16 Other disorders of pancreatic internal secretion
0.956 0.044 0.000
D50.8 Other iron deficiency anaemias
0.954 0.046 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.953 0.047 0.000
E16.2 Hypoglycaemia, unspecified
0.943 0.057 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.939 0.061 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.928 0.072 0.000
Chapter VIII Diseases of the ear and mastoid process
0.923 0.077 0.000
B25-B34 Other viral diseases
0.918 0.082 0.000
E10.4 With neurological complications
0.918 0.082 0.000
E10.1 With ketoacidosis
0.912 0.088 0.000
H30-H36 Disorders of choroid and retina
0.912 0.088 0.000
E11.3 With ophthalmic complications
0.904 0.096 0.000
B35-B49 Mycoses
0.900 0.100 0.000
D50.9 Iron deficiency anaemia, unspecified
0.899 0.101 0.000
G30-G32 Other degenerative diseases of the nervous system
0.897 0.103 0.000
H36 Retinal disorders in diseases classified elsewhere
0.890 0.110 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.888 0.112 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.888 0.112 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.887 0.113 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.880 0.120 0.000
H36.0 Diabetic retinopathy
0.874 0.126 0.000
M75 Shoulder lesions
0.874 0.126 0.000
E11.2 With renal complications
0.873 0.127 0.000
G62 Other polyneuropathies
0.871 0.129 0.000
H02 Other disorders of eyelid
0.871 0.129 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.864 0.136 0.000
E14 Unspecified diabetes mellitus
0.852 0.148 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.851 0.149 0.000
E11.4 With neurological complications
0.847 0.153 0.000
M80-M85 Disorders of bone density and structure
0.846 0.154 0.000
B34 Viral infection of unspecified site
0.846 0.154 0.000
H60-H62 Diseases of external ear
0.845 0.155 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.844 0.156 0.000
H04 Disorders of lachrymal system
0.839 0.161 0.000
O00-O08 Pregnancy with abortive outcome
0.838 0.162 0.000
M79.0 Rheumatism, unspecified
0.836 0.164 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.836 0.164 0.000
G90-G99 Other disorders of the nervous system
0.835 0.165 0.000
G20-G26 Extrapyramidal and movement disorders
0.835 0.165 0.000
E10.2 With renal complications
0.833 0.167 0.000
M79.1 Myalgia
0.828 0.172 0.000
E00-E07 Disorders of thyroid gland
0.827 0.173 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.825 0.175 0.000
G63.2 Diabetic polyneuropathy
0.824 0.176 0.000
E40-E46 Malnutrition
0.824 0.176 0.000
D51 Vitamin B12 deficiency anaemia
0.822 0.178 0.000
O03 Spontaneous abortion
0.819 0.181 0.000
G62.9 Polyneuropathy, unspecified
0.816 0.184 0.000
M75.0 Adhesive capsulitis of shoulder
0.814 0.186 0.000
H05 Disorders of orbit
0.809 0.191 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.808 0.192 0.000
M91-M94 Chondropathies
0.800 0.200 0.000
E14.3 With ophthalmic complications
0.800 0.200 0.000
B37 Candidiasis
0.798 0.202 0.000
M40-M43 Deforming dorsopathies
0.797 0.203 0.000
G61 Inflammatory polyneuropathy
0.795 0.204 0.000
B34.9 Viral infection, unspecified
0.794 0.206 0.000
H65-H75 Diseases of middle ear and mastoid
0.792 0.208 0.000
H53-H54 Visual disturbances and blindness
0.792 0.208 0.000
H00 Hordeolum and chalazion
0.791 0.209 0.000
H02.1 Ectropion of eyelid
0.790 0.210 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.786 0.214 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.783 0.217 0.000
O03.4 Incomplete, without complication
0.782 0.218 0.000
Chapter X Diseases of the respiratory system
0.782 0.218 0.000
W50-W64 Exposure to animate mechanical forces
0.781 0.219 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.780 0.220 0.000
B25 Cytomegaloviral disease
0.780 0.220 0.000
Chapter XXII Codes for special purposes
0.779 0.221 0.000
B35 Dermatophytosis
0.774 0.226 0.000
Y52 Agents primarily affecting the cardiovascular system
0.772 0.228 0.000
A80-A89 Viral infections of the central nervous system
0.770 0.230 0.000
E11.5 With peripheral circulatory complications
0.768 0.232 0.000
M06.3 Rheumatoid nodule
0.763 0.237 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.761 0.239 0.000
H04.2 Epiphora
0.760 0.240 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.760 0.240 0.000
H55-H59 Other disorders of eye and adnexa
0.757 0.243 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.755 0.244 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.755 0.245 0.000
V10-V19 Pedal cyclist injured in transport accident
0.755 0.245 0.000
X60-X84 Intentional self-harm
0.751 0.249 0.000
M75.2 Bicipital tendinitis
0.751 0.249 0.000
B15-B19 Viral hepatitis
0.751 0.249 0.000
M79.7 Fibromyalgia
0.751 0.249 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.750 0.250 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.749 0.251 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.747 0.253 0.000
Y43 Primarily systemic agents
0.746 0.254 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.746 0.254 0.000
Y42.5 Other oestrogens and progestogens
0.745 0.255 0.000
H60 Otitis externa
0.745 0.255 0.000
Y95 Nosocomial condition
0.741 0.259 0.000
E10.5 With peripheral circulatory complications
0.738 0.261 0.000
M75.5 Bursitis of shoulder
0.738 0.262 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.737 0.263 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
O04 Medical abortion
0.735 0.264 0.000
V40-V49 Car occupant injured in transport accident
0.733 0.267 0.000
O03.9 Complete or unspecified, without complication
0.733 0.267 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.731 0.269 0.000
H31 Other disorders of choroid
0.728 0.272 0.000
M84 Disorders of continuity of bone
0.728 0.272 0.000
M10 Gout
0.727 0.273 0.000
V80-V89 Other land transport accidents
0.726 0.274 0.000
M79.9 Soft tissue disorder, unspecified
0.722 0.277 0.000
B27 Infectious mononucleosis
0.721 0.278 0.000
H02.6 Xanthelasma of eyelid
0.719 0.281 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
G31.8 Other specified degenerative diseases of nervous system
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
H34 Retinal vascular occlusions
0.717 0.283 0.000
M79.16 Myalgia (Lower leg)
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.713 0.287 0.000
H61 Other disorders of external ear
0.712 0.288 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.711 0.289 0.000
H17 Corneal scars and opacities
0.711 0.289 0.000
H18 Other disorders of cornea
0.710 0.290 0.000
M79.5 Residual foreign body in soft tissue
0.709 0.291 0.000
M05.8 Other seropositive rheumatoid arthritis
0.708 0.291 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.708 0.291 0.000
M05.2 Rheumatoid vasculitis
0.708 0.291 0.000
M05.1 Rheumatoid lung disease
0.708 0.291 0.000
M05.0 Felty's syndrome
0.708 0.291 0.000
H02.4 Ptosis of eyelid
0.708 0.292 0.000
H01 Other inflammation of eyelid
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.702 0.297 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.702 0.297 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.702 0.297 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.702 0.297 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.702 0.297 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.702 0.297 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.702 0.297 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.702 0.297 0.000
E11.8 With unspecified complications
0.702 0.298 0.000
E11.7 With multiple complications
0.702 0.298 0.000
E11.0 With coma
0.702 0.298 0.000
M76 Enthesopathies of lower limb, excluding foot
0.700 0.300 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.700 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.700 0.300 0.000
H16 Keratitis
0.699 0.301 0.000
O00 Ectopic pregnancy
0.699 0.301 0.000
M79.2 Neuralgia and neuritis, unspecified
0.699 0.301 0.000
E15 Nondiabetic hypoglycaemic coma
0.698 0.301 0.000
D53 Other nutritional anaemias
0.698 0.302 0.000
W20-W49 Exposure to inanimate mechanical forces
0.698 0.302 0.000
Y35-Y36 Legal intervention and operations of war
0.698 0.302 0.000
Y10-Y34 Event of undetermined intent
0.698 0.302 0.000
Y00-Y09 Assault
0.698 0.302 0.000
X85-X99 Assault
0.698 0.302 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.302 0.000
X30-X39 Exposure to forces of nature
0.698 0.302 0.000
X10-X19 Contact with heat and hot substances
0.698 0.302 0.000
X00-X09 Exposure to smoke, fire and flames
0.698 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.698 0.302 0.000
W75-W84 Other accidental threats to breathing
0.698 0.302 0.000
W65-W74 Accidental drowning and submersion
0.698 0.302 0.000
V98-V99 Other and unspecified transport accidents
0.698 0.302 0.000
V95-V97 Air and space transport accidents
0.698 0.302 0.000
V90-V94 Water transport accidents
0.698 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.698 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.698 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.698 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.302 0.000
M72 Fibroblastic disorders
0.697 0.302 0.000
O20 Haemorrhage in early pregnancy
0.697 0.303 0.000
E46 Unspecified protein-energy malnutrition
0.697 0.303 0.000
G30 Alzheimer's disease
0.697 0.303 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.697 0.303 0.000
H53 Visual disturbances
0.697 0.303 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.696 0.304 0.000
G96 Other disorders of central nervous system
0.695 0.305 0.000
D50.1 Sideropenic dysphagia
0.694 0.306 0.000
H05.8 Other disorders of orbit
0.694 0.306 0.000
Q80-Q89 Other congenital malformations
0.693 0.307 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.692 0.308 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.692 0.308 0.000
M71 Other bursopathies
0.692 0.308 0.000
B37.8 Candidiasis of other sites
0.691 0.309 0.000
G70-G73 Diseases of myoneural junction and muscle
0.691 0.309 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.690 0.310 0.000
D55-D59 Haemolytic anaemias
0.690 0.310 0.000
J40-J47 Chronic lower respiratory diseases
0.689 0.311 0.000
Y57 Other and unspecified drugs and medicaments
0.688 0.311 0.000
E11.6 With other specified complications
0.688 0.312 0.000
B99-B99 Other infectious diseases
0.688 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.688 0.312 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.688 0.312 0.000
B50-B64 Protozoal diseases
0.688 0.312 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.688 0.312 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.688 0.312 0.000
A75-A79 Rickettsioses
0.688 0.312 0.000
A70-A74 Other diseases caused by chlamydiae
0.688 0.312 0.000
A65-A69 Other spirochaetal diseases
0.688 0.312 0.000
A20-A28 Certain zoonotic bacterial diseases
0.688 0.312 0.000
A15-A19 Tuberculosis
0.688 0.312 0.000
B65-B83 Helminthiases
0.686 0.314 0.000
G60 Hereditary and idiopathic neuropathy
0.686 0.314 0.000
G64 Other disorders of peripheral nervous system
0.686 0.314 0.000
G20 Parkinson's disease
0.686 0.314 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.685 0.315 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.685 0.315 0.000
E16.4 Abnormal secretion of gastrin
0.685 0.315 0.000
E16.3 Increased secretion of glucagon
0.685 0.315 0.000
E16.1 Other hypoglycaemia
0.685 0.315 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.685 0.315 0.000
E04 Other non-toxic goitre
0.685 0.315 0.000
B44 Aspergillosis
0.685 0.315 0.000
J30-J39 Other diseases of upper respiratory tract
0.685 0.315 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.684 0.316 0.000
G61.8 Other inflammatory polyneuropathies
0.683 0.317 0.000
H80-H83 Diseases of inner ear
0.681 0.319 0.000
B25.9 Cytomegaloviral disease, unspecified
0.680 0.320 0.000
M77 Other enthesopathies
0.677 0.323 0.000
H02.3 Blepharochalasis
0.677 0.323 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.677 0.323 0.000
B35.1 Tinea unguium
0.676 0.324 0.000
M94 Other disorders of cartilage
0.676 0.324 0.000
H04.4 Chronic inflammation of lachrymal passages
0.676 0.324 0.000
J47 Bronchiectasis
0.676 0.324 0.000
M11 Other crystal arthropathies
0.674 0.326 0.000
Y59 Other and unspecified vaccines and biological substances
0.673 0.326 0.000
Y58 Bacterial vaccines
0.673 0.326 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.673 0.326 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.673 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.673 0.326 0.000
Y48 Anaesthetics and therapeutic gases
0.673 0.326 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.673 0.326 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.673 0.326 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.673 0.326 0.000
D80-D89 Certain disorders involving the immune mechanism
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.672 0.327 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
E07 Other disorders of thyroid
0.672 0.328 0.000
M79.10 Myalgia (Multiple sites)
0.672 0.328 0.000
H10-H13 Disorders of conjunctiva
0.671 0.329 0.000
M65-M68 Disorders of synovium and tendon
0.671 0.329 0.000
E11.9 Without complications
0.670 0.330 0.000
G31.0 Circumscribed brain atrophy
0.668 0.332 0.000
D60-D64 Aplastic and other anaemias
0.668 0.332 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.665 0.335 0.000
M79.3 Panniculitis, unspecified
0.665 0.335 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.665 0.335 0.000
H65 Nonsuppurative otitis media
0.663 0.337 0.000
G62.0 Drug-induced polyneuropathy
0.662 0.338 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.661 0.339 0.000
M75.9 Shoulder lesion, unspecified
0.660 0.340 0.000
B33 Other viral diseases, not elsewhere classified
0.658 0.341 0.000
B30 Viral conjunctivitis
0.658 0.341 0.000
B26 Mumps
0.658 0.341 0.000
E11.1 With ketoacidosis
0.658 0.342 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.658 0.342 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.658 0.342 0.000
H40-H42 Glaucoma
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.657 0.343 0.000
H53.1 Subjective visual disturbances
0.657 0.343 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.344 0.000
M07 Psoriatic and enteropathic arthropathies
0.656 0.344 0.000
J33 Nasal polyp
0.655 0.345 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.654 0.346 0.000
H30 Chorioretinal inflammation
0.654 0.346 0.000
H43-H45 Disorders of vitreous body and globe
0.653 0.347 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.652 0.348 0.000
Q50-Q56 Congenital malformations of genital organs
0.652 0.348 0.000
H02.5 Other disorders affecting eyelid function
0.650 0.350 0.000
G90 Disorders of autonomic nervous system
0.649 0.351 0.000
Y44 Agents primarily affecting blood constituents
0.646 0.354 0.000
M86-M90 Other osteopathies
0.646 0.354 0.000
M06.0 Seronegative rheumatoid arthritis
0.646 0.354 0.000
B48 Other mycoses, not elsewhere classified
0.645 0.355 0.000
B47 Mycetoma
0.645 0.355 0.000
B46 Zygomycosis
0.645 0.355 0.000
B45 Cryptococcosis
0.645 0.355 0.000
B43 Chromomycosis and phaeomycotic abscess
0.645 0.355 0.000
B42 Sporotrichosis
0.645 0.355 0.000
B41 Paracoccidioidomycosis
0.645 0.355 0.000
B40 Blastomycosis
0.645 0.355 0.000
B39 Histoplasmosis
0.645 0.355 0.000
B38 Coccidioidomycosis
0.645 0.355 0.000
B36 Other superficial mycoses
0.645 0.355 0.000
B49 Unspecified mycosis
0.645 0.355 0.000
H60.9 Otitis externa, unspecified
0.645 0.355 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.645 0.355 0.000
G25 Other extrapyramidal and movement disorders
0.644 0.356 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.643 0.357 0.000
W55 Bitten or struck by other mammals
0.643 0.357 0.000
O85-O92 Complications predominantly related to the puerperium
0.643 0.357 0.000
M82 Osteoporosis in diseases classified elsewhere
0.642 0.358 0.000
Q60-Q64 Congenital malformations of the urinary system
0.642 0.358 0.000
H72 Perforation of tympanic membrane
0.640 0.360 0.000
M41 Scoliosis
0.638 0.362 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.638 0.362 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.636 0.363 0.000
Q35-Q37 Cleft lip and cleft palate
0.636 0.363 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.636 0.363 0.000
J42 Unspecified chronic bronchitis
0.636 0.364 0.000
G24 Dystonia
0.635 0.365 0.000
W00-W19 Falls
0.635 0.365 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.634 0.366 0.000
A87 Viral meningitis
0.634 0.366 0.000
E04.9 Non-toxic goitre, unspecified
0.633 0.367 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.632 0.368 0.000
E06 Thyroiditis
0.632 0.368 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.631 0.369 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.631 0.369 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.631 0.369 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.631 0.369 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.631 0.369 0.000
G63.1 Polyneuropathy in neoplastic disease
0.631 0.369 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.631 0.369 0.000
M75.8 Other shoulder lesions
0.627 0.373 0.000
O04.9 Complete or unspecified, without complication
0.626 0.374 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.625 0.375 0.000
G62.2 Polyneuropathy due to other toxic agents
0.624 0.376 0.000
G62.1 Alcoholic polyneuropathy
0.624 0.376 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.624 0.376 0.000
H02.2 Lagophthalmos
0.624 0.376 0.000
M79.79 Fibromyalgia (Site unspecified)
0.624 0.376 0.000
Q00-Q07 Congenital malformations of the nervous system
0.623 0.377 0.000
B37.9 Candidiasis, unspecified
0.623 0.377 0.000
V20-V29 Motorcycle rider injured in transport accident
0.622 0.378 0.000
G93 Other disorders of brain
0.621 0.379 0.000
H71 Cholesteatoma of middle ear
0.621 0.379 0.000
A30-A49 Other bacterial diseases
0.621 0.379 0.000
G91 Hydrocephalus
0.620 0.380 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.620 0.380 0.000
H21 Other disorders of iris and ciliary body
0.620 0.380 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.620 0.380 0.000
H15 Disorders of sclera
0.620 0.380 0.000
H18.4 Corneal degeneration
0.620 0.380 0.000
D52 Folate deficiency anaemia
0.620 0.380 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.618 0.381 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.618 0.382 0.000
J33.9 Nasal polyp, unspecified
0.615 0.385 0.000
Y54.3 Benzothiadiazine derivatives
0.614 0.385 0.000
H74 Other disorders of middle ear and mastoid
0.613 0.387 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.612 0.387 0.000
E14.8 With unspecified complications
0.611 0.389 0.000
E14.7 With multiple complications
0.611 0.389 0.000
E14.6 With other specified complications
0.611 0.389 0.000
E14.5 With peripheral circulatory complications
0.611 0.389 0.000
E14.4 With neurological complications
0.611 0.389 0.000
E14.2 Withrenal complications
0.611 0.389 0.000
E14.1 With ketoacidosis
0.611 0.389 0.000
E14.0 With coma
0.611 0.389 0.000
B37.3 Candidiasis of vulva and vagina
0.611 0.389 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.610 0.390 0.000
Y98 Lifestyle-related condition
0.610 0.390 0.000
Y97 Environmental-pollution-related condition
0.610 0.390 0.000
Y96 Work-related condition
0.610 0.390 0.000
M79.18 Myalgia (Other)
0.610 0.390 0.000
H61.3 Acquired stenosis of external ear canal
0.609 0.390 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.609 0.391 0.000
M85 Other disorders of bone density and structure
0.608 0.391 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.607 0.393 0.000
M83 Adult osteomalacia
0.606 0.394 0.000
B34.8 Other viral infections of unspecified site
0.606 0.394 0.000
B34.4 Papovirus infection, unspecified
0.606 0.394 0.000
B34.3 Parvovirus infection, unspecified
0.606 0.394 0.000
B34.2 Coronavirus infection, unspecified
0.606 0.394 0.000
B34.1 Enterovirus infection, unspecified
0.606 0.394 0.000
B34.0 Adenovirus infection, unspecified
0.606 0.394 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.606 0.394 0.000
Y43.1 Antineoplastic antimetabolites
0.605 0.395 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.604 0.396 0.000
M80 Osteoporosis with pathological fracture
0.603 0.397 0.000
H04.9 Disorder of lachrymal system, unspecified
0.602 0.398 0.000
H04.8 Other disorders of lachrymal system
0.602 0.398 0.000
H04.6 Other changes in lachrymal passages
0.602 0.398 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.602 0.398 0.000
H04.0 Dacryoadenitis
0.602 0.398 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.600 0.399 0.000
O07 Failed attempted abortion
0.600 0.399 0.000
O06 Unspecified abortion
0.600 0.399 0.000
O05 Other abortion
0.600 0.399 0.000
O01 Hydatidiform mole
0.600 0.399 0.000
H17.9 Corneal scar and opacity, unspecified
0.600 0.399 0.000
M79.08 Rheumatism, unspecified (Other)
0.600 0.400 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.600 0.400 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.600 0.400 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.600 0.400 0.000
M79.04 Rheumatism, unspecified (Hand)
0.600 0.400 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.600 0.400 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.600 0.400 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.600 0.400 0.000
O00.1 Tubal pregnancy
0.600 0.400 0.000
Y42.9 Other and unspecified hormone antagonists
0.599 0.401 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.599 0.401 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.599 0.401 0.000
Y42.4 Oral contraceptives
0.599 0.401 0.000
Y42.2 Antithyroid drugs
0.599 0.401 0.000
Y42.1 Thyroid hormones and substitutes
0.599 0.401 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.599 0.401 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.599 0.401 0.000
G92 Toxic encephalopathy
0.599 0.401 0.000
G23 Other degenerative diseases of basal ganglia
0.598 0.401 0.000
G21 Secondary Parkinsonism
0.598 0.401 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.598 0.401 0.000
G22 Parkinsonism in diseases classified elsewhere
0.598 0.401 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.598 0.402 0.000
H31.0 Chorioretinal scars
0.597 0.403 0.000
O04.4 Incomplete, without complication
0.597 0.403 0.000
B16 Acute hepatitis B
0.594 0.405 0.000
H60.1 Cellulitis of external ear
0.594 0.406 0.000
M79.19 Myalgia (Site unspecified)
0.594 0.406 0.000
M79.17 Myalgia (Ankle and foot)
0.594 0.406 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.594 0.406 0.000
M79.14 Myalgia (Hand)
0.594 0.406 0.000
M79.13 Myalgia (Forearm)
0.594 0.406 0.000
M79.12 Myalgia (Upper arm)
0.594 0.406 0.000
M79.11 Myalgia (Shoulder region)
0.594 0.406 0.000
Y42.7 Androgens and anabolic congeners
0.593 0.407 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.593 0.407 0.000
E00 Congenital iodine-deficiency syndrome
0.593 0.407 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.593 0.407 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.593 0.407 0.000
Y43.4 Immunosuppressive agents
0.593 0.407 0.000
M06.34 Rheumatoid nodule (Hand)
0.592 0.407 0.000
G31.2 Degeneration of nervous system due to alcohol
0.591 0.408 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.591 0.408 0.000
M70.4 Prepatellar bursitis
0.591 0.409 0.000
M43 Other deforming dorsopathies
0.591 0.409 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.590 0.409 0.000
E45 Retarded development following protein-energy malnutrition
0.590 0.409 0.000
E43 Unspecified severe protein-energy malnutrition
0.590 0.409 0.000
E42 Marasmic kwashiorkor
0.590 0.409 0.000
E41 Nutritional marasmus
0.590 0.409 0.000
E40 Kwashiorkor
0.590 0.409 0.000
D69 Purpura and other haemorrhagic conditions
0.590 0.410 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.590 0.410 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.590 0.410 0.000
D51.2 Transcobalamin II deficiency
0.590 0.410 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.590 0.410 0.000
H00.1 Chalazion
0.589 0.411 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.587 0.413 0.000
O03.7 Complete or unspecified, complicated by embolism
0.587 0.413 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.587 0.413 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.587 0.413 0.000
O03.3 Incomplete, with other and unspecified complications
0.587 0.413 0.000
O03.2 Incomplete, complicated by embolism
0.587 0.413 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.587 0.413 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.587 0.413 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.587 0.413 0.000
D66 Hereditary factor VIII deficiency
0.586 0.414 0.000
H80 Otosclerosis
0.586 0.414 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.585 0.414 0.000
H05.0 Acute inflammation of orbit
0.585 0.415 0.000
M84.0 Malunion of fracture
0.585 0.415 0.000
M81 Osteoporosis without pathological fracture
0.584 0.416 0.000
E03 Other hypothyroidism
0.584 0.416 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.582 0.418 0.000
M50-M54 Other dorsopathies
0.581 0.419 0.000
B27.9 Infectious mononucleosis, unspecified
0.580 0.420 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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