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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72973582
log Bayes Factor = 18.8418
Chromosome 11   position 102,558,258  (GRCh37) Explore rs72973582 on Ensembl!
Variant rs72973582 is part of Cluster X0051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
H33 Retinal detachments and breaks
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.994 0.006 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.992 0.008 0.000
I20-I25 Ischaemic heart diseases
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
H33.0 Retinal detachment with retinal break
0.989 0.011 0.000
S50-S59 Injuries to the elbow and forearm
0.989 0.011 0.000
I25 Chronic ischaemic heart disease
0.984 0.016 0.000
Z87 Personal history of other diseases and conditions
0.983 0.017 0.000
Z95.4 Presence of other heart-valve replacement
0.978 0.022 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.978 0.022 0.000
S00-S09 Injuries to the head
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.974 0.026 0.000
Z93 Artificial opening status
0.973 0.027 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.972 0.028 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.967 0.033 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.962 0.038 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.959 0.041 0.000
Z95.2 Presence of prosthetic heart valve
0.959 0.041 0.000
S52 Fracture of forearm
0.957 0.043 0.000
Z87.1 Personal history of diseases of the digestive system
0.955 0.045 0.000
H33.2 Serous retinal detachment
0.952 0.048 0.000
G90-G99 Other disorders of the nervous system
0.950 0.050 0.000
Z88.0 Personal history of allergy to penicillin
0.949 0.051 0.000
R50-R69 General symptoms and signs
0.949 0.051 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.946 0.054 0.000
I25.2 Old myocardial infarction
0.943 0.057 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.942 0.058 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.941 0.059 0.000
I50 Heart failure
0.936 0.064 0.000
H35 Other retinal disorders
0.927 0.073 0.000
F30-F39 Mood [affective] disorders
0.924 0.076 0.000
Z98 Other postsurgical states
0.924 0.076 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.923 0.077 0.000
R21 Rash and other nonspecific skin eruption
0.922 0.078 0.000
Y83.6 Removal of other organ (partial) (total)
0.922 0.078 0.000
Z96 Presence of other functional implants
0.918 0.082 0.000
F41 Other anxiety disorders
0.917 0.083 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.914 0.086 0.000
H53-H54 Visual disturbances and blindness
0.906 0.094 0.000
Y86 Sequelae of other accidents
0.904 0.096 0.000
Chapter VIII Diseases of the ear and mastoid process
0.902 0.098 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.899 0.101 0.000
S02 Fracture of skull and facial bones
0.899 0.101 0.000
S09 Other and unspecified injuries of head
0.898 0.102 0.000
F40 Phobic anxiety disorders
0.896 0.104 0.000
I21 Acute myocardial infarction
0.896 0.104 0.000
Chapter I Certain infectious and parasitic diseases
0.895 0.105 0.000
Z85 Personal history of malignant neoplasm
0.886 0.114 0.000
S80-S89 Injuries to the knee and lower leg
0.882 0.118 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.882 0.118 0.000
Z93.3 Colostomy status
0.878 0.122 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.878 0.122 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.877 0.123 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.877 0.123 0.000
H90-H95 Other disorders of ear
0.877 0.123 0.000
S51 Open wound of forearm
0.876 0.124 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.873 0.127 0.000
Z96.1 Presence of intraocular lens
0.871 0.129 0.000
Chapter II Neoplasms
0.870 0.130 0.000
Z93.0 Tracheostomy status
0.869 0.131 0.000
G95 Other diseases of spinal cord
0.869 0.131 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.867 0.133 0.000
G57 Mononeuropathies of lower limb
0.864 0.136 0.000
Z97 Presence of other devices
0.863 0.137 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.863 0.137 0.000
R55 Syncope and collapse
0.862 0.138 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.861 0.139 0.000
I49 Other cardiac arrhythmias
0.860 0.140 0.000
S52.6 Fracture of lower end of both ulna and radius
0.859 0.141 0.000
I60-I69 Cerebrovascular diseases
0.859 0.141 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.858 0.142 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.853 0.147 0.000
I05-I09 Chronic rheumatic heart diseases
0.853 0.147 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.852 0.148 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.852 0.148 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.850 0.150 0.000
I25.3 Aneurysm of heart
0.849 0.151 0.000
R20 Disturbances of skin sensation
0.849 0.151 0.000
H91 Other hearing loss
0.849 0.151 0.000
W00-W19 Falls
0.849 0.151 0.000
I50.0 Congestive heart failure
0.848 0.152 0.000
H10-H13 Disorders of conjunctiva
0.848 0.152 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.848 0.152 0.000
C15-C26 Malignant neoplasms of digestive organs
0.846 0.154 0.000
H34 Retinal vascular occlusions
0.845 0.155 0.000
S06 Intracranial injury
0.845 0.155 0.000
H54 Blindness and low vision
0.842 0.158 0.000
S09.9 Unspecified injury of head
0.842 0.158 0.000
Z96.7 Presence of other bone and tendon implants
0.842 0.158 0.000
Z88.5 Personal history of allergy to narcotic agent
0.841 0.159 0.000
Y83.4 Other reconstructive surgery
0.841 0.159 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.840 0.160 0.000
F40.2 Specific (isolated) phobias
0.838 0.162 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.837 0.163 0.000
Z87.8 Personal history of other specified conditions
0.836 0.164 0.000
Y85 Sequelae of transport accidents
0.832 0.168 0.000
R59 Enlarged lymph nodes
0.831 0.169 0.000
H43-H45 Disorders of vitreous body and globe
0.829 0.171 0.000
I50.1 Left ventricular failure
0.829 0.171 0.000
H91.9 Hearing loss, unspecified
0.829 0.171 0.000
I22 Subsequent myocardial infarction
0.828 0.172 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.828 0.172 0.000
R53 Malaise and fatigue
0.827 0.173 0.000
Z95.3 Presence of xenogenic heart valve
0.826 0.173 0.000
H04 Disorders of lachrymal system
0.824 0.176 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.823 0.177 0.000
G57.6 Lesion of plantar nerve
0.823 0.177 0.000
G20-G26 Extrapyramidal and movement disorders
0.821 0.179 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.820 0.180 0.000
S20-S29 Injuries to the thorax
0.820 0.180 0.000
W50-W64 Exposure to animate mechanical forces
0.820 0.180 0.000
Z98.1 Arthrodesis status
0.819 0.181 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.817 0.183 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.816 0.184 0.000
Z98.0 Intestinal bypass and anastomosis status
0.814 0.186 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.811 0.189 0.000
H33.1 Retinoschisis and retinal cysts
0.811 0.189 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.811 0.189 0.000
S50 Superficial injury of forearm
0.811 0.189 0.000
F31 Bipolar affective disorder
0.808 0.192 0.000
H33.3 Retinal breaks without detachment
0.808 0.192 0.000
R57 Shock, not elsewhere classified
0.807 0.193 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.804 0.196 0.000
Z93.6 Other artificial openings of urinary tract status
0.802 0.198 0.000
F20 Schizophrenia
0.799 0.201 0.000
Chapter XXII Codes for special purposes
0.799 0.201 0.000
R56 Convulsions, not elsewhere classified
0.798 0.202 0.000
I25.5 Ischaemic cardiomyopathy
0.797 0.203 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.796 0.204 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.796 0.204 0.000
C16 Malignant neoplasm of stomach
0.796 0.204 0.000
S52.0 Fracture of upper end of ulna
0.793 0.207 0.000
H04.2 Epiphora
0.793 0.207 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.792 0.208 0.000
I49.9 Cardiac arrhythmia, unspecified
0.790 0.210 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.788 0.212 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.787 0.213 0.000
I30 Acute pericarditis
0.786 0.214 0.000
R52 Pain, not elsewhere classified
0.784 0.216 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.783 0.217 0.000
F33 Recurrent depressive disorder
0.782 0.218 0.000
F41.2 Mixed anxiety and depressive disorder
0.779 0.221 0.000
R42 Dizziness and giddiness
0.774 0.226 0.000
S52.5 Fracture of lower end of radius
0.774 0.226 0.000
S02.4 Fracture of malar and maxillary bones
0.773 0.227 0.000
F42 Obsessive-compulsive disorder
0.771 0.228 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.771 0.228 0.000
R60 Oedema, not elsewhere classified
0.771 0.229 0.000
H55-H59 Other disorders of eye and adnexa
0.770 0.230 0.000
I33 Acute and subacute endocarditis
0.769 0.231 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.767 0.233 0.000
S51.0 Open wound of elbow
0.767 0.233 0.000
R47-R49 Symptoms and signs involving speech and voice
0.764 0.236 0.000
S80 Superficial injury of lower leg
0.763 0.237 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.762 0.238 0.000
F99-F99 Unspecified mental disorder
0.760 0.240 0.000
T93 Sequelae of injuries of lower limb
0.760 0.240 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.760 0.240 0.000
S52.1 Fracture of upper end of radius
0.759 0.240 0.000
S05 Injury of eye and orbit
0.758 0.242 0.000
H36 Retinal disorders in diseases classified elsewhere
0.757 0.243 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.757 0.243 0.000
I46 Cardiac arrest
0.756 0.244 0.000
G95.8 Other specified diseases of spinal cord
0.755 0.245 0.000
T90 Sequelae of injuries of head
0.755 0.245 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.754 0.246 0.000
H35.3 Degeneration of macula and posterior pole
0.754 0.246 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.752 0.248 0.000
I31 Other diseases of pericardium
0.751 0.249 0.000
S60-S69 Injuries to the wrist and hand
0.751 0.249 0.000
H33.5 Other retinal detachments
0.749 0.251 0.000
S52.7 Multiple fractures of forearm
0.749 0.251 0.000
Z93.1 Gastrostomy status
0.748 0.252 0.000
I47 Paroxysmal tachycardia
0.747 0.253 0.000
S81 Open wound of lower leg
0.744 0.256 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.744 0.256 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.743 0.257 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.743 0.257 0.000
R23 Other skin changes
0.742 0.258 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.742 0.258 0.000
H35.4 Peripheral retinal degeneration
0.742 0.258 0.000
H11 Other disorders of conjunctiva
0.741 0.259 0.000
H35.0 Background retinopathy and retinal vascular changes
0.740 0.260 0.000
Z85.6 Personal history of leukaemia
0.739 0.261 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.739 0.261 0.000
G54 Nerve root and plexus disorders
0.739 0.261 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.738 0.262 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.738 0.262 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
F45 Somatoform disorders
0.737 0.263 0.000
I37 Pulmonary valve disorders
0.737 0.263 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.736 0.264 0.000
I05 Rheumatic mitral valve diseases
0.736 0.264 0.000
H35.5 Hereditary retinal dystrophy
0.736 0.264 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.735 0.265 0.000
G90 Disorders of autonomic nervous system
0.735 0.265 0.000
S90-S99 Injuries to the ankle and foot
0.734 0.266 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.734 0.266 0.000
G95.2 Cord compression, unspecified
0.733 0.267 0.000
R50 Fever of unknown origin
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
R52.2 Other chronic pain
0.732 0.268 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.732 0.268 0.000
G58 Other mononeuropathies
0.731 0.269 0.000
Z94 Transplanted organ and tissue status
0.731 0.269 0.000
Z89 Acquired absence of limb
0.731 0.269 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.730 0.270 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.729 0.271 0.000
T91 Sequelae of injuries of neck and trunk
0.729 0.271 0.000
Z81 Family history of mental and behavioural disorders
0.729 0.271 0.000
Z83 Family history of other specific disorders
0.728 0.272 0.000
I50.9 Heart failure, unspecified
0.727 0.273 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.726 0.274 0.000
I42 Cardiomyopathy
0.724 0.276 0.000
Y83.9 Surgical procedure, unspecified
0.724 0.276 0.000
F60-F69 Disorders of adult personality and behaviour
0.723 0.277 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.723 0.277 0.000
F30 Manic episode
0.723 0.277 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.722 0.278 0.000
L03 Cellulitis
0.721 0.279 0.000
S02.1 Fracture of base of skull
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
H90 Conductive and sensorineural hearing loss
0.719 0.281 0.000
H43 Disorders of vitreous body
0.719 0.281 0.000
Z97.4 Presence of external hearing-aid
0.718 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H31 Other disorders of choroid
0.717 0.283 0.000
H30 Chorioretinal inflammation
0.717 0.283 0.000
C25 Malignant neoplasm of pancreas
0.717 0.283 0.000
H54.7 Unspecified visual loss
0.717 0.283 0.000
S00 Superficial injury of head
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
H33.4 Traction detachment of retina
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X50-X57 Overexertion, travel and privation
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V80-V89 Other land transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.715 0.285 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.715 0.285 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.714 0.286 0.000
W20-W49 Exposure to inanimate mechanical forces
0.714 0.286 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.286 0.000
F70-F79 Mental retardation
0.713 0.286 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.714 0.286 0.000
H35.9 Retinal disorder, unspecified
0.713 0.286 0.000
E20-E35 Disorders of other endocrine glands
0.713 0.287 0.000
B35-B49 Mycoses
0.713 0.287 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.712 0.288 0.000
I23 Certain current complications following acute myocardial infarction
0.711 0.289 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
H93 Other disorders of ear, not elsewhere classified
0.710 0.290 0.000
Y83.5 Amputation of limb(s)
0.710 0.290 0.000
G82 Paraplegia and tetraplegia
0.709 0.291 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.709 0.291 0.000
Y88 Sequelae of surgical and medical care as external cause
0.709 0.291 0.000
S59 Other and unspecified injuries of forearm
0.709 0.291 0.000
S58 Traumatic amputation of forearm
0.709 0.291 0.000
S57 Crushing injury of forearm
0.709 0.291 0.000
S56 Injury of muscle and tendon at forearm level
0.709 0.291 0.000
S55 Injury of blood vessels at forearm level
0.709 0.291 0.000
S54 Injury of nerves at forearm level
0.709 0.291 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.709 0.291 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.707 0.293 0.000
A30-A49 Other bacterial diseases
0.706 0.294 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.706 0.294 0.000
Z93.2 Ileostomy status
0.706 0.294 0.000
R57.2 Septic shock
0.705 0.295 0.000
I25.6 Silent myocardial ischaemia
0.705 0.295 0.000
I25.4 Coronary artery aneurysm
0.705 0.295 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.705 0.295 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.705 0.295 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.703 0.297 0.000
I38 Endocarditis, valve unspecified
0.703 0.297 0.000
Z90.5 Acquired absence of kidney
0.703 0.297 0.000
C91 Lymphoid leukaemia
0.701 0.298 0.000
E00-E07 Disorders of thyroid gland
0.701 0.299 0.000
F48 Other neurotic disorders
0.701 0.299 0.000
F44 Dissociative [conversion] disorders
0.701 0.299 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.701 0.299 0.000
F20.9 Schizophrenia, unspecified
0.700 0.300 0.000
I44 Atrioventricular and left bundle-branch block
0.700 0.300 0.000
S08 Traumatic amputation of part of head
0.699 0.301 0.000
S07 Crushing injury of head
0.699 0.301 0.000
S04 Injury of cranial nerves
0.699 0.301 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.698 0.301 0.000
I48 Atrial fibrillation and flutter
0.698 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.698 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.698 0.301 0.000
I40 Acute myocarditis
0.698 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.698 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.698 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.698 0.301 0.000
Y85.0 Sequelae of motor-vehicle accident
0.698 0.302 0.000
I71 Aortic aneurysm and dissection
0.698 0.302 0.000
R59.1 Generalised enlarged lymph nodes
0.698 0.302 0.000
Z93.9 Artificial opening status, unspecified
0.698 0.302 0.000
Z93.8 Other artificial opening status
0.698 0.302 0.000
I95 Hypotension
0.698 0.302 0.000
H54.4 Blindness, one eye
0.697 0.303 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.697 0.303 0.000
I49.5 Sick sinus syndrome
0.697 0.303 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.697 0.303 0.000
I69 Sequelae of cerebrovascular disease
0.697 0.303 0.000
C16.5 Lesser curvature of stomach, unspecified
0.696 0.304 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.695 0.305 0.000
B65-B83 Helminthiases
0.694 0.305 0.000
E10-E14 Diabetes mellitus
0.694 0.306 0.000
H54.0 Blindness, both eyes
0.694 0.306 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.694 0.306 0.000
G93 Other disorders of brain
0.692 0.308 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.692 0.308 0.000
R13 Dysphagia
0.691 0.309 0.000
F31.9 Bipolar affective disorder, unspecified
0.691 0.309 0.000
S51.9 Open wound of forearm, part unspecified
0.691 0.309 0.000
R56.8 Other and unspecified convulsions
0.690 0.310 0.000
Y89 Sequelae of other external causes
0.690 0.310 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.689 0.311 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.689 0.311 0.000
C16.9 Stomach, unspecified
0.689 0.311 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.687 0.313 0.000
S52.9 Fracture of forearm, part unspecified
0.686 0.314 0.000
S52.8 Fracture of other parts of forearm
0.686 0.314 0.000
S52.4 Fracture of shafts of both ulna and radius
0.686 0.314 0.000
S52.3 Fracture of shaft of radius
0.686 0.314 0.000
S52.2 Fracture of shaft of ulna
0.686 0.314 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.686 0.314 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.685 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
S50.9 Superficial injury of forearm, unspecified
0.683 0.317 0.000
H34.2 Other retinal artery occlusions
0.683 0.317 0.000
S02.3 Fracture of orbital floor
0.682 0.318 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.682 0.318 0.000
S02.6 Fracture of mandible
0.682 0.318 0.000
H34.8 Other retinal vascular occlusions
0.681 0.319 0.000
C17 Malignant neoplasm of small intestine
0.681 0.319 0.000
T66-T78 Other and unspecified effects of external causes
0.681 0.319 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.681 0.319 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.681 0.319 0.000
G92 Toxic encephalopathy
0.681 0.319 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.681 0.319 0.000
R62 Lack of expected normal physiological development
0.681 0.319 0.000
R64 Cachexia
0.681 0.319 0.000
R58 Haemorrhage, not elsewhere classified
0.681 0.319 0.000
T92 Sequelae of injuries of upper limb
0.679 0.321 0.000
B15-B19 Viral hepatitis
0.679 0.321 0.000
I63 Cerebral infarction
0.679 0.321 0.000
R54 Senility
0.678 0.322 0.000
I62 Other nontraumatic intracranial haemorrhage
0.677 0.323 0.000
S52.00 Fracture of upper end of ulna (closed)
0.676 0.324 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.675 0.325 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.675 0.325 0.000
C18 Malignant neoplasm of colon
0.674 0.326 0.000
W18 Other fall on same level
0.674 0.326 0.000
F43 Reaction to severe stress, and adjustment disorders
0.673 0.327 0.000
F20.0 Paranoid schizophrenia
0.672 0.328 0.000
I47.2 Ventricular tachycardia
0.670 0.330 0.000
F01 Vascular dementia
0.669 0.331 0.000
I24 Other acute ischaemic heart diseases
0.669 0.331 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.668 0.332 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.667 0.333 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.667 0.333 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.667 0.333 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.666 0.334 0.000
H35.8 Other specified retinal disorders
0.665 0.335 0.000
H35.7 Separation of retinal layers
0.665 0.335 0.000
H35.6 Retinal haemorrhage
0.665 0.335 0.000
H35.2 Other proliferative retinopathy
0.665 0.335 0.000
H35.1 Retinopathy of prematurity
0.665 0.335 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.665 0.335 0.000
C92 Myeloid leukaemia
0.665 0.335 0.000
S02.8 Fractures of other skull and facial bones
0.664 0.336 0.000
E03 Other hypothyroidism
0.664 0.336 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.664 0.336 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.663 0.337 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.663 0.337 0.000
F38 Other mood [affective] disorders
0.662 0.337 0.000
F34 Persistent mood [affective] disorders
0.662 0.337 0.000
F39 Unspecified mood [affective] disorder
0.662 0.337 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.662 0.338 0.000
G52 Disorders of other cranial nerves
0.662 0.338 0.000
W19 Unspecified fall
0.662 0.338 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.661 0.339 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.660 0.339 0.000
S06.5 Traumatic subdural haemorrhage
0.660 0.340 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.659 0.341 0.000
T39.0 Salicylates
0.659 0.341 0.000
B95-B98 Bacterial, viral and other infectious agents
0.659 0.341 0.000
S06.8 Other intracranial injuries
0.659 0.341 0.000
Z96.9 Presence of functional implant, unspecified
0.658 0.342 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.658 0.342 0.000
Z96.4 Presence of endocrine implants
0.658 0.342 0.000
Z96.3 Presence of artificial larynx
0.658 0.342 0.000
Z96.2 Presence of otological and audiological implants
0.658 0.342 0.000
F41.8 Other specified anxiety disorders
0.658 0.342 0.000
F41.3 Other mixed anxiety disorders
0.658 0.342 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.657 0.343 0.000
H11.9 Disorder of conjunctiva, unspecified
0.657 0.343 0.000
S02.0 Fracture of vault of skull
0.657 0.343 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.656 0.344 0.000
Z93.5 Cystostomy status
0.656 0.344 0.000
S29 Other and unspecified injuries of thorax
0.655 0.345 0.000
T98 Sequelae of other and unspecified effects of external causes
0.655 0.345 0.000
T95 Sequelae of burns, corrosions and frostbite
0.655 0.345 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.655 0.345 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.655 0.345 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.655 0.345 0.000
I31.3 Pericardial effusion (noninflammatory)
0.655 0.345 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.654 0.346 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.654 0.346 0.000
H57 Other disorders of eye and adnexa
0.654 0.346 0.000
L03.1 Cellulitis of other parts of limb
0.653 0.347 0.000
G25 Other extrapyramidal and movement disorders
0.653 0.347 0.000
S80.8 Other superficial injuries of lower leg
0.652 0.348 0.000
L20-L30 Dermatitis and eczema
0.652 0.348 0.000
I05.9 Mitral valve disease, unspecified
0.652 0.348 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.652 0.348 0.000
S02.2 Fracture of nasal bones
0.652 0.348 0.000
G20 Parkinson's disease
0.652 0.348 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.651 0.349 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.651 0.349 0.000
G50 Disorders of trigeminal nerve
0.651 0.349 0.000
I30.9 Acute pericarditis, unspecified
0.651 0.349 0.000
Y83.8 Other surgical procedures
0.649 0.350 0.000
R59.0 Localised enlarged lymph nodes
0.649 0.351 0.000
F32 Depressive episode
0.649 0.351 0.000
H04.1 Other disorders of lachrymal gland
0.648 0.352 0.000
Z29 Need for other prophylactic measures
0.648 0.352 0.000
A00-A09 Intestinal infectious diseases
0.648 0.352 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.647 0.353 0.000
R17 Unspecified jaundice
0.646 0.354 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.646 0.354 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.645 0.355 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.644 0.355 0.000
S02.7 Multiple fractures involving skull and facial bones
0.644 0.355 0.000
S02.5 Fracture of tooth
0.644 0.355 0.000
F41.1 Generalised anxiety disorder
0.644 0.356 0.000
Z95.0 Presence of cardiac pacemaker
0.644 0.356 0.000
S09.8 Other specified injuries of head
0.643 0.356 0.000
S09.7 Multiple injuries of head
0.643 0.356 0.000
S09.2 Traumatic rupture of ear drum
0.643 0.356 0.000
S09.1 Injury of muscle and tendon of head
0.643 0.356 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.643 0.356 0.000
Z90.1 Acquired absence of breast(s)
0.643 0.357 0.000
I07 Rheumatic tricuspid valve diseases
0.643 0.357 0.000
S52.50 Fracture of lower end of radius (closed)
0.643 0.357 0.000
F40.9 Phobic anxiety disorder, unspecified
0.642 0.357 0.000
F40.8 Other phobic anxiety disorders
0.642 0.357 0.000
F40.1 Social phobias
0.642 0.357 0.000
F40.0 Agoraphobia
0.642 0.357 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.642 0.357 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.642 0.357 0.000
G95.9 Disease of spinal cord, unspecified
0.642 0.358 0.000
B99-B99 Other infectious diseases
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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