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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73049732
log Bayes Factor = 12.0096
Chromosome 3   position 25,343,723  (GRCh37) Explore rs73049732 on Ensembl!
Variant rs73049732 is part of Cluster X0091

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
C78.0 Secondary malignant neoplasm of lung
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.995 0.005 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.994 0.006 0.000
S80-S89 Injuries to the knee and lower leg
0.992 0.008 0.000
C34 Malignant neoplasm of bronchus and lung
0.991 0.009 0.000
D68 Other coagulation defects
0.989 0.011 0.000
I35 Nonrheumatic aortic valve disorders
0.989 0.011 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.982 0.018 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.981 0.019 0.000
S82 Fracture of lower leg, including ankle
0.977 0.023 0.000
C34.1 Upper lobe, bronchus or lung
0.977 0.023 0.000
C79 Secondary malignant neoplasm of other sites
0.964 0.036 0.000
I60-I69 Cerebrovascular diseases
0.960 0.040 0.000
I35.0 Aortic (valve) stenosis
0.960 0.040 0.000
S82.8 Fractures of other parts of lower leg
0.957 0.043 0.000
Chapter VI Diseases of the nervous system
0.956 0.044 0.000
I51 Complications and ill-defined descriptions of heart disease
0.951 0.049 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.944 0.056 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.926 0.074 0.000
D68.9 Coagulation defect, unspecified
0.923 0.077 0.000
C34.9 Bronchus or lung, unspecified
0.922 0.078 0.000
I46 Cardiac arrest
0.921 0.079 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.919 0.081 0.000
S70-S79 Injuries to the hip and thigh
0.917 0.083 0.000
C80 Malignant neoplasm without specification of site
0.915 0.085 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.913 0.087 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.912 0.088 0.000
I51.7 Cardiomegaly
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.906 0.094 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.905 0.095 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.896 0.104 0.000
D69 Purpura and other haemorrhagic conditions
0.892 0.108 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.891 0.109 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.888 0.112 0.000
D68.8 Other specified coagulation defects
0.886 0.114 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.886 0.114 0.000
D45 Polycythaemia vera
0.886 0.114 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.883 0.117 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.879 0.121 0.000
S82.3 Fracture of lower end of tibia
0.877 0.123 0.000
Y40 Systemic antibiotics
0.877 0.123 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.872 0.128 0.000
I10-I15 Hypertensive diseases
0.870 0.130 0.000
G90-G99 Other disorders of the nervous system
0.866 0.134 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.863 0.137 0.000
C78.2 Secondary malignant neoplasm of pleura
0.859 0.141 0.000
D68.5 Primary Thrombophilia
0.858 0.142 0.000
S90-S99 Injuries to the ankle and foot
0.857 0.143 0.000
C50-C50 Malignant neoplasm of breast
0.856 0.144 0.000
S00-S09 Injuries to the head
0.853 0.147 0.000
Y95 Nosocomial condition
0.852 0.148 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.852 0.148 0.000
D68.2 Hereditary deficiency of other clotting factors
0.851 0.149 0.000
S72 Fracture of femur
0.848 0.152 0.000
I12 Hypertensive renal disease
0.846 0.154 0.000
C77.1 Intrathoracic lymph nodes
0.844 0.156 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.843 0.157 0.000
W00-W19 Falls
0.841 0.159 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.838 0.162 0.000
H65-H75 Diseases of middle ear and mastoid
0.835 0.165 0.000
S50-S59 Injuries to the elbow and forearm
0.834 0.166 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.833 0.167 0.000
Y52 Agents primarily affecting the cardiovascular system
0.828 0.172 0.000
I62 Other nontraumatic intracranial haemorrhage
0.827 0.173 0.000
S80 Superficial injury of lower leg
0.825 0.175 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.821 0.179 0.000
I46.9 Cardiac arrest, unspecified
0.821 0.179 0.000
O47 False labour
0.820 0.180 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.819 0.181 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.818 0.182 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.813 0.187 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.812 0.188 0.000
S10-S19 Injuries to the neck
0.811 0.188 0.000
Chapter XXII Codes for special purposes
0.811 0.189 0.000
T79-T79 Certain early complications of trauma
0.811 0.189 0.000
S00 Superficial injury of head
0.810 0.190 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.809 0.191 0.000
S89 Other and unspecified injuries of lower leg
0.808 0.192 0.000
S82.30 Fracture of lower end of tibia (closed)
0.806 0.194 0.000
I12.0 Hypertensive renal disease with renal failure
0.806 0.194 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.804 0.196 0.000
D48.5 Skin
0.802 0.198 0.000
D66 Hereditary factor VIII deficiency
0.797 0.203 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.793 0.207 0.000
I44 Atrioventricular and left bundle-branch block
0.793 0.207 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.793 0.207 0.000
I60 Subarachnoid haemorrhage
0.792 0.208 0.000
I31 Other diseases of pericardium
0.792 0.208 0.000
Y40.9 Systemic antibiotic, unspecified
0.790 0.210 0.000
C34.2 Middle lobe, bronchus or lung
0.789 0.211 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.788 0.211 0.000
I65.2 Occlusion and stenosis of carotid artery
0.788 0.212 0.000
T90 Sequelae of injuries of head
0.787 0.213 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.785 0.215 0.000
D70 Agranulocytosis
0.779 0.221 0.000
G91 Hydrocephalus
0.778 0.222 0.000
I46.0 Cardiac arrest with successful resuscitation
0.778 0.222 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.778 0.222 0.000
I61 Intracerebral haemorrhage
0.777 0.222 0.000
S72.0 Fracture of neck of femur
0.777 0.223 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.777 0.223 0.000
Chapter I Certain infectious and parasitic diseases
0.774 0.226 0.000
I35.8 Other aortic valve disorders
0.773 0.227 0.000
I69 Sequelae of cerebrovascular disease
0.773 0.227 0.000
I51.8 Other ill-defined heart diseases
0.773 0.227 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.772 0.228 0.000
I50 Heart failure
0.772 0.228 0.000
I49 Other cardiac arrhythmias
0.772 0.228 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.769 0.231 0.000
I67 Other cerebrovascular diseases
0.765 0.235 0.000
I35.1 Aortic (valve) insufficiency
0.764 0.236 0.000
T91 Sequelae of injuries of neck and trunk
0.763 0.237 0.000
V10-V19 Pedal cyclist injured in transport accident
0.763 0.237 0.000
Y44 Agents primarily affecting blood constituents
0.763 0.237 0.000
S86 Injury of muscle and tendon at lower leg level
0.762 0.238 0.000
D48.1 Connective and other soft tissue
0.759 0.241 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.757 0.243 0.000
O36 Maternal care for other known or suspected foetal problems
0.757 0.243 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.756 0.244 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.755 0.245 0.000
O47.9 False labour, unspecified
0.754 0.246 0.000
C50 Malignant neoplasm of breast
0.752 0.248 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.752 0.248 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.751 0.249 0.000
D55-D59 Haemolytic anaemias
0.748 0.251 0.000
G35 Multiple sclerosis
0.748 0.252 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.748 0.252 0.000
T93 Sequelae of injuries of lower limb
0.747 0.253 0.000
S82.0 Fracture of patella
0.746 0.254 0.000
I12.9 Hypertensive renal disease without renal failure
0.744 0.256 0.000
T66-T78 Other and unspecified effects of external causes
0.744 0.256 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.743 0.257 0.000
H90-H95 Other disorders of ear
0.743 0.257 0.000
S00.9 Superficial injury of head, part unspecified
0.741 0.259 0.000
S60-S69 Injuries to the wrist and hand
0.740 0.260 0.000
H71 Cholesteatoma of middle ear
0.739 0.261 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.739 0.261 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.734 0.266 0.000
O32.1 Maternal care for breech presentation
0.732 0.268 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.732 0.268 0.000
Chapter VII Diseases of the eye and adnexa
0.732 0.268 0.000
D75 Other diseases of blood and blood-forming organs
0.732 0.268 0.000
X60-X84 Intentional self-harm
0.731 0.269 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.730 0.270 0.000
I35.9 Aortic valve disorder, unspecified
0.729 0.271 0.000
S00.8 Superficial injury of other parts of head
0.729 0.271 0.000
S72.00 Fracture of neck of femur (closed)
0.727 0.273 0.000
C80.9 Malignant neoplasm, unspecified
0.725 0.275 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.275 0.000
S82.6 Fracture of lateral malleolus
0.723 0.277 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.721 0.279 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.719 0.281 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
D67 Hereditary factor IX deficiency
0.713 0.286 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.713 0.286 0.000
D48.7 Other specified sites
0.713 0.287 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.713 0.287 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.713 0.287 0.000
C32 Malignant neoplasm of larynx
0.713 0.287 0.000
C31 Malignant neoplasm of accessory sinuses
0.713 0.287 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.713 0.287 0.000
C37 Malignant neoplasm of thymus
0.713 0.287 0.000
C33 Malignant neoplasm of trachea
0.713 0.287 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.712 0.288 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.712 0.288 0.000
I05-I09 Chronic rheumatic heart diseases
0.712 0.288 0.000
S88 Traumatic amputation of lower leg
0.711 0.289 0.000
S87 Crushing injury of lower leg
0.711 0.289 0.000
S85 Injury of blood vessels at lower leg level
0.711 0.289 0.000
S84 Injury of nerves at lower leg level
0.711 0.289 0.000
C34.8 Overlapping lesion of bronchus and lung
0.710 0.290 0.000
D46 Myelodysplastic syndromes
0.710 0.290 0.000
C77.4 Inguinal and lower limb lymph nodes
0.710 0.290 0.000
D68.6 Other Thrombophilia
0.709 0.290 0.000
D68.4 Acquired coagulation factor deficiency
0.709 0.290 0.000
D68.1 Hereditary factor XI deficiency
0.709 0.290 0.000
D68.0 Von Willebrand's disease
0.709 0.290 0.000
I30 Acute pericarditis
0.709 0.291 0.000
C34.3 Lower lobe, bronchus or lung
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.293 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.707 0.293 0.000
Y86 Sequelae of other accidents
0.706 0.294 0.000
S80.9 Superficial injury of lower leg, unspecified
0.705 0.295 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.705 0.295 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.704 0.296 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.704 0.296 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.704 0.296 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.704 0.296 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.704 0.296 0.000
G20-G26 Extrapyramidal and movement disorders
0.703 0.296 0.000
Y59 Other and unspecified vaccines and biological substances
0.703 0.297 0.000
Y58 Bacterial vaccines
0.703 0.297 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.703 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.703 0.297 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.703 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.703 0.297 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
Y48 Anaesthetics and therapeutic gases
0.703 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.703 0.297 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.703 0.297 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
I44.1 Atrioventricular block, second degree
0.701 0.299 0.000
I78 Diseases of capillaries
0.701 0.299 0.000
S82.9 Fracture of lower leg, part unspecified
0.700 0.299 0.000
S82.7 Multiple fractures of lower leg
0.700 0.299 0.000
O43 Placental disorders
0.699 0.301 0.000
Y45.1 Salicylates
0.698 0.302 0.000
W20-W49 Exposure to inanimate mechanical forces
0.698 0.302 0.000
A30-A49 Other bacterial diseases
0.696 0.304 0.000
S70 Superficial injury of hip and thigh
0.695 0.305 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.694 0.306 0.000
G40-G47 Episodic and paroxysmal disorders
0.693 0.307 0.000
V80-V89 Other land transport accidents
0.692 0.308 0.000
S52 Fracture of forearm
0.691 0.308 0.000
C79.6 Secondary malignant neoplasm of ovary
0.691 0.309 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.691 0.309 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.691 0.309 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.691 0.309 0.000
C77.3 Axillary and upper limb lymph nodes
0.690 0.310 0.000
H74 Other disorders of middle ear and mastoid
0.689 0.311 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.688 0.312 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
C77.9 Lymph node, unspecified
0.688 0.312 0.000
S82.86 Maisonneuve's fracture
0.686 0.313 0.000
S82.81 Fractures of other parts of lower leg (open)
0.686 0.313 0.000
Q60-Q64 Congenital malformations of the urinary system
0.686 0.314 0.000
D72 Other disorders of white blood cells
0.685 0.315 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.684 0.316 0.000
S82.2 Fracture of shaft of tibia
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.316 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.683 0.317 0.000
I51.6 Cardiovascular disease, unspecified
0.682 0.318 0.000
I51.5 Myocardial degeneration
0.682 0.318 0.000
I51.4 Myocarditis, unspecified
0.682 0.318 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.682 0.318 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.682 0.318 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.682 0.318 0.000
I51.0 Cardiac septal defect, acquired
0.682 0.318 0.000
Y45.2 Propionic acid derivatives
0.681 0.319 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.680 0.320 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.679 0.320 0.000
O80-O84 Delivery
0.679 0.320 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.679 0.321 0.000
S81 Open wound of lower leg
0.679 0.321 0.000
S02 Fracture of skull and facial bones
0.678 0.321 0.000
T14 Injury of unspecified body region
0.678 0.322 0.000
I67.8 Other specified cerebrovascular diseases
0.677 0.323 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.676 0.324 0.000
C34.0 Main bronchus
0.675 0.325 0.000
S89.9 Unspecified injury of lower leg
0.675 0.325 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.674 0.326 0.000
Y40.0 Penicillins
0.673 0.327 0.000
I49.4 Other and unspecified premature depolarisation
0.673 0.327 0.000
C09 Malignant neoplasm of tonsil
0.673 0.327 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.673 0.327 0.000
I50.1 Left ventricular failure
0.672 0.328 0.000
L60-L75 Disorders of skin appendages
0.670 0.330 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.669 0.331 0.000
S82.4 Fracture of fibula alone
0.669 0.331 0.000
D48.0 Bone and articular cartilage
0.669 0.331 0.000
H72 Perforation of tympanic membrane
0.669 0.331 0.000
C50.2 Upper-inner quadrant of breast
0.667 0.333 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.666 0.334 0.000
S72.2 Subtrochanteric fracture
0.666 0.334 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.666 0.334 0.000
T90.5 Sequelae of intracranial injury
0.665 0.335 0.000
C10 Malignant neoplasm of oropharynx
0.664 0.335 0.000
G90 Disorders of autonomic nervous system
0.664 0.336 0.000
G91.8 Other hydrocephalus
0.664 0.336 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.664 0.336 0.000
G70-G73 Diseases of myoneural junction and muscle
0.664 0.336 0.000
I33 Acute and subacute endocarditis
0.663 0.337 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.663 0.337 0.000
Chapter V Mental and behavioural disorders
0.662 0.338 0.000
S90 Superficial injury of ankle and foot
0.662 0.338 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.661 0.339 0.000
I46.1 Sudden cardiac death, so described
0.661 0.339 0.000
S40-S49 Injuries to the shoulder and upper arm
0.660 0.340 0.000
I71 Aortic aneurysm and dissection
0.660 0.340 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.660 0.340 0.000
T98 Sequelae of other and unspecified effects of external causes
0.659 0.341 0.000
T95 Sequelae of burns, corrosions and frostbite
0.659 0.341 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.659 0.341 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
S79 Other and unspecified injuries of hip and thigh
0.658 0.342 0.000
S78 Traumatic amputation of hip and thigh
0.658 0.342 0.000
S77 Crushing injury of hip and thigh
0.658 0.342 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.658 0.342 0.000
S75 Injury of blood vessels at hip and thigh level
0.658 0.342 0.000
S74 Injury of nerves at hip and thigh level
0.658 0.342 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.658 0.342 0.000
S71 Open wound of hip and thigh
0.658 0.342 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.658 0.342 0.000
G91.9 Hydrocephalus, unspecified
0.657 0.343 0.000
T86 Failure and rejection of transplanted organs and tissues
0.657 0.343 0.000
G96 Other disorders of central nervous system
0.657 0.343 0.000
W10 Fall on and from stairs and steps
0.657 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.657 0.343 0.000
Y57 Other and unspecified drugs and medicaments
0.655 0.344 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.655 0.345 0.000
D48.6 Breast
0.655 0.345 0.000
D48.4 Peritoneum
0.655 0.345 0.000
D48.3 Retroperitoneum
0.655 0.345 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.655 0.345 0.000
Y43 Primarily systemic agents
0.655 0.345 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.654 0.346 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.654 0.346 0.000
Y98 Lifestyle-related condition
0.654 0.346 0.000
Y97 Environmental-pollution-related condition
0.654 0.346 0.000
Y96 Work-related condition
0.654 0.346 0.000
D60-D64 Aplastic and other anaemias
0.654 0.346 0.000
C78.7 Secondary malignant neoplasm of liver
0.652 0.348 0.000
Y85 Sequelae of transport accidents
0.652 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.652 0.348 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.651 0.349 0.000
O42 Premature rupture of membranes
0.650 0.350 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.650 0.350 0.000
O85-O92 Complications predominantly related to the puerperium
0.649 0.351 0.000
S82.5 Fracture of medial malleolus
0.647 0.353 0.000
O41 Other disorders of amniotic fluid and membranes
0.645 0.355 0.000
S91 Open wound of ankle and foot
0.645 0.355 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.645 0.355 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.644 0.355 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.643 0.356 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.643 0.357 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.643 0.357 0.000
D74 Methaemoglobinaemia
0.643 0.357 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.643 0.357 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.643 0.357 0.000
Y52.1 Calcium-channel blockers
0.642 0.358 0.000
Y88 Sequelae of surgical and medical care as external cause
0.642 0.358 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.642 0.358 0.000
G37 Other demyelinating diseases of central nervous system
0.642 0.358 0.000
O36.9 Maternal care for foetal problem, unspecified
0.642 0.358 0.000
I77 Other disorders of arteries and arterioles
0.641 0.359 0.000
S72.3 Fracture of shaft of femur
0.640 0.360 0.000
D69.9 Haemorrhagic condition, unspecified
0.639 0.361 0.000
D69.8 Other specified haemorrhagic conditions
0.639 0.361 0.000
D69.5 Secondary thrombocytopenia
0.639 0.361 0.000
D69.4 Other primary thrombocytopenia
0.639 0.361 0.000
D69.2 Other nonthrombocytopenic purpura
0.639 0.361 0.000
D69.1 Qualitative platelet defects
0.639 0.361 0.000
D69.0 Allergic purpura
0.639 0.361 0.000
C50.4 Upper-outer quadrant of breast
0.639 0.361 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.639 0.361 0.000
O45 Premature separation of placenta [abruptio placentae]
0.639 0.361 0.000
O33 Maternal care for known or suspected disproportion
0.639 0.361 0.000
O31 Complications specific to multiple gestation
0.639 0.361 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.639 0.361 0.000
O46.9 Antepartum haemorrhage, unspecified
0.637 0.363 0.000
O44 Placenta praevia
0.635 0.364 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.635 0.365 0.000
Y45.8 Other analgesics and antipyretics
0.635 0.365 0.000
Y45.5 4-Aminophenol derivatives
0.635 0.365 0.000
Y45.4 Antirheumatics
0.635 0.365 0.000
H80-H83 Diseases of inner ear
0.635 0.365 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.635 0.365 0.000
I31.9 Disease of pericardium, unspecified
0.635 0.365 0.000
T92 Sequelae of injuries of upper limb
0.633 0.366 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.633 0.367 0.000
I51.9 Heart disease, unspecified
0.633 0.367 0.000
Y45.0 Opioids and related analgesics
0.632 0.368 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.632 0.368 0.000
H66 Suppurative and unspecified otitis media
0.632 0.368 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.631 0.369 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.631 0.369 0.000
W07 Fall involving chair
0.630 0.369 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.630 0.370 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.630 0.370 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.630 0.370 0.000
I65.1 Occlusion and stenosis of basilar artery
0.630 0.370 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.630 0.370 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.629 0.371 0.000
S19 Other and unspecified injuries of neck
0.629 0.371 0.000
S82.31 Fracture of lower end of tibia (open)
0.629 0.371 0.000
D47.1 Chronic myeloproliferative disease
0.629 0.371 0.000
Y40.7 Antifungal antibiotics, systemically used
0.629 0.371 0.000
Y40.6 Rifamycins
0.629 0.371 0.000
Y40.5 Aminoglycosides
0.629 0.371 0.000
Y40.4 Tetracyclines
0.629 0.371 0.000
Y40.3 Macrolides
0.629 0.371 0.000
Y40.2 Chloramphenicol group
0.629 0.371 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.629 0.371 0.000
H90 Conductive and sensorineural hearing loss
0.628 0.372 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.627 0.373 0.000
D41.4 Bladder
0.627 0.373 0.000
W06 Fall involving bed
0.627 0.373 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.627 0.373 0.000
D69.6 Thrombocytopenia, unspecified
0.625 0.375 0.000
A00-A09 Intestinal infectious diseases
0.625 0.375 0.000
S50 Superficial injury of forearm
0.624 0.376 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.624 0.376 0.000
I15 Secondary hypertension
0.624 0.376 0.000
I13 Hypertensive heart and renal disease
0.624 0.376 0.000
T91.3 Sequelae of injury of spinal cord
0.623 0.377 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.621 0.379 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.621 0.379 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.621 0.379 0.000
G92 Toxic encephalopathy
0.621 0.379 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.620 0.380 0.000
Q80-Q89 Other congenital malformations
0.620 0.380 0.000
Q35-Q37 Cleft lip and cleft palate
0.620 0.380 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.620 0.380 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.620 0.380 0.000
T87 Complications peculiar to reattachment and amputation
0.619 0.381 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.619 0.381 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.618 0.382 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.618 0.382 0.000
D75.1 Secondary polycythaemia
0.617 0.382 0.000
Y40.8 Other systemic antibiotics
0.617 0.383 0.000
O40 Polyhydramnios
0.617 0.383 0.000
I44.2 Atrioventricular block, complete
0.617 0.383 0.000
I38 Endocarditis, valve unspecified
0.617 0.383 0.000
C77.8 Lymph nodes of multiple regions
0.615 0.385 0.000
C50.0 Nipple and areola
0.615 0.385 0.000
S99 Other and unspecified injuries of ankle and foot
0.614 0.385 0.000
S98 Traumatic amputation of ankle and foot
0.614 0.385 0.000
S97 Crushing injury of ankle and foot
0.614 0.385 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.614 0.385 0.000
S95 Injury of blood vessels at ankle and foot level
0.614 0.385 0.000
S94 Injury of nerves at ankle and foot level
0.614 0.385 0.000
S92 Fracture of foot, except ankle
0.614 0.386 0.000
G82 Paraplegia and tetraplegia
0.614 0.386 0.000
O36.5 Maternal care for poor foetal growth
0.614 0.386 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.613 0.387 0.000
A41 Other septicaemia
0.613 0.387 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.613 0.387 0.000
I49.1 Atrial premature depolarisation
0.612 0.388 0.000
S06 Intracranial injury
0.612 0.388 0.000
S08 Traumatic amputation of part of head
0.611 0.389 0.000
S07 Crushing injury of head
0.611 0.389 0.000
S05 Injury of eye and orbit
0.611 0.389 0.000
S04 Injury of cranial nerves
0.611 0.389 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.611 0.389 0.000
I70 Atherosclerosis
0.611 0.389 0.000
S51 Open wound of forearm
0.611 0.389 0.000
Y89 Sequelae of other external causes
0.610 0.389 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.610 0.389 0.000
S12 Fracture of neck
0.610 0.390 0.000
C92 Myeloid leukaemia
0.609 0.391 0.000
O32.0 Maternal care for unstable lie
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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