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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73149261
log Bayes Factor = 14.8706
Chromosome 20   position 61,039,662  (GRCh37) Explore rs73149261 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
I20-I25 Ischaemic heart diseases
0.986 0.014 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
I60-I69 Cerebrovascular diseases
0.984 0.016 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
N20-N23 Urolithiasis
0.978 0.022 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.974 0.026 0.000
N17-N19 Renal failure
0.974 0.026 0.000
E10-E14 Diabetes mellitus
0.971 0.029 0.000
E10 Insulin-dependent diabetes mellitus
0.967 0.033 0.000
N20 Calculus of kidney and ureter
0.965 0.035 0.000
G90-G99 Other disorders of the nervous system
0.955 0.045 0.000
N20.1 Calculus of ureter
0.951 0.049 0.000
I20 Angina pectoris
0.946 0.054 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.944 0.056 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.943 0.057 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.942 0.058 0.000
Chapter V Mental and behavioural disorders
0.941 0.059 0.000
B35-B49 Mycoses
0.940 0.060 0.000
E10.9 Without complications
0.937 0.063 0.000
N18 Chronic renal failure
0.934 0.066 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.923 0.077 0.000
I30-I52 Other forms of heart disease
0.918 0.082 0.000
I10-I15 Hypertensive diseases
0.914 0.086 0.000
B37 Candidiasis
0.914 0.086 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.913 0.087 0.000
Chapter XI Diseases of the digestive system
0.912 0.088 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.911 0.089 0.000
T93 Sequelae of injuries of lower limb
0.910 0.090 0.000
M05-M14 Inflammatory polyarthropathies
0.910 0.090 0.000
S40-S49 Injuries to the shoulder and upper arm
0.908 0.092 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.907 0.093 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.907 0.093 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.903 0.097 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.902 0.098 0.000
K31 Other diseases of stomach and duodenum
0.901 0.099 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.901 0.099 0.000
I25 Chronic ischaemic heart disease
0.900 0.100 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.899 0.101 0.000
M20-M25 Other joint disorders
0.898 0.102 0.000
G62 Other polyneuropathies
0.897 0.103 0.000
B37.8 Candidiasis of other sites
0.895 0.105 0.000
R19.4 Change in bowel habit
0.895 0.105 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.892 0.108 0.000
M15-M19 Arthrosis
0.891 0.109 0.000
N17 Acute renal failure
0.890 0.110 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.889 0.111 0.000
N23 Unspecified renal colic
0.889 0.111 0.000
E70-E90 Metabolic disorders
0.886 0.114 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.885 0.115 0.000
F30-F39 Mood [affective] disorders
0.883 0.117 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.881 0.119 0.000
M50-M54 Other dorsopathies
0.878 0.122 0.000
I20.8 Other forms of angina pectoris
0.875 0.125 0.000
K31.7 Polyp of stomach and duodenum
0.873 0.127 0.000
M17 Gonarthrosis [arthrosis of knee]
0.873 0.127 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.869 0.131 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.868 0.132 0.000
K25 Gastric ulcer
0.867 0.133 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.867 0.133 0.000
M17.1 Other primary gonarthrosis
0.866 0.134 0.000
F31 Bipolar affective disorder
0.863 0.137 0.000
N25-N29 Other disorders of kidney and ureter
0.860 0.140 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.857 0.143 0.000
I67 Other cerebrovascular diseases
0.856 0.144 0.000
R50-R69 General symptoms and signs
0.854 0.146 0.000
R17 Unspecified jaundice
0.854 0.146 0.000
G93 Other disorders of brain
0.854 0.146 0.000
G62.9 Polyneuropathy, unspecified
0.850 0.150 0.000
G91 Hydrocephalus
0.850 0.150 0.000
K31.8 Other specified diseases of stomach and duodenum
0.850 0.150 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.850 0.150 0.000
Chapter VIII Diseases of the ear and mastoid process
0.850 0.150 0.000
I24 Other acute ischaemic heart diseases
0.849 0.151 0.000
G96 Other disorders of central nervous system
0.846 0.154 0.000
L40-L45 Papulosquamous disorders
0.845 0.155 0.000
S42 Fracture of shoulder and upper arm
0.844 0.156 0.000
M22 Disorders of patella
0.844 0.156 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.843 0.157 0.000
I35 Nonrheumatic aortic valve disorders
0.843 0.157 0.000
N18.3 Chronic kidney disease, stage 3
0.837 0.163 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.836 0.164 0.000
N20.0 Calculus of kidney
0.835 0.165 0.000
I20.9 Angina pectoris, unspecified
0.835 0.165 0.000
Q60-Q64 Congenital malformations of the urinary system
0.834 0.166 0.000
T90 Sequelae of injuries of head
0.834 0.166 0.000
B25-B34 Other viral diseases
0.831 0.169 0.000
V20-V29 Motorcycle rider injured in transport accident
0.830 0.170 0.000
N17.9 Acute renal failure, unspecified
0.830 0.170 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.829 0.171 0.000
T91 Sequelae of injuries of neck and trunk
0.828 0.172 0.000
A30-A49 Other bacterial diseases
0.827 0.173 0.000
I65.2 Occlusion and stenosis of carotid artery
0.826 0.174 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.823 0.177 0.000
M05 Seropositive rheumatoid arthritis
0.821 0.179 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.820 0.180 0.000
S60-S69 Injuries to the wrist and hand
0.818 0.182 0.000
E10.2 With renal complications
0.817 0.183 0.000
N19 Unspecified renal failure
0.816 0.184 0.000
Y40 Systemic antibiotics
0.814 0.186 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.814 0.186 0.000
E10.5 With peripheral circulatory complications
0.813 0.187 0.000
L40 Psoriasis
0.812 0.188 0.000
I61 Intracerebral haemorrhage
0.810 0.190 0.000
R53 Malaise and fatigue
0.807 0.193 0.000
I60 Subarachnoid haemorrhage
0.806 0.194 0.000
M60-M63 Disorders of muscles
0.805 0.195 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.804 0.196 0.000
S42.0 Fracture of clavicle
0.804 0.196 0.000
N18.9 Chronic renal failure, unspecified
0.804 0.196 0.000
M91-M94 Chondropathies
0.803 0.197 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.803 0.197 0.000
G30-G32 Other degenerative diseases of the nervous system
0.802 0.198 0.000
K20 Oesophagitis
0.802 0.198 0.000
M22.4 Chondromalacia patellae
0.802 0.198 0.000
S10-S19 Injuries to the neck
0.802 0.198 0.000
R69 Unknown and unspecified causes of morbidity
0.799 0.201 0.000
S20-S29 Injuries to the thorax
0.798 0.202 0.000
Y43 Primarily systemic agents
0.798 0.202 0.000
N18.5 Chronic kidney disease, stage 5
0.796 0.204 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.796 0.204 0.000
N00-N08 Glomerular diseases
0.795 0.205 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.795 0.205 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.794 0.206 0.000
B99-B99 Other infectious diseases
0.794 0.206 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.794 0.206 0.000
W20-W49 Exposure to inanimate mechanical forces
0.791 0.209 0.000
M00-M03 Infectious arthropathies
0.790 0.210 0.000
M50 Cervical disk disorders
0.789 0.211 0.000
I30 Acute pericarditis
0.789 0.211 0.000
E10.4 With neurological complications
0.787 0.213 0.000
H50 Other strabismus
0.787 0.213 0.000
I25.5 Ischaemic cardiomyopathy
0.782 0.218 0.000
T98 Sequelae of other and unspecified effects of external causes
0.781 0.219 0.000
H10-H13 Disorders of conjunctiva
0.780 0.220 0.000
R59 Enlarged lymph nodes
0.779 0.221 0.000
E10.3 With ophthalmic complications
0.778 0.222 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.778 0.222 0.000
I15 Secondary hypertension
0.777 0.223 0.000
T86 Failure and rejection of transplanted organs and tissues
0.777 0.223 0.000
R10 Abdominal and pelvic pain
0.776 0.224 0.000
H65-H75 Diseases of middle ear and mastoid
0.775 0.225 0.000
G91.9 Hydrocephalus, unspecified
0.775 0.225 0.000
S42.00 Fracture of clavicle (closed)
0.775 0.225 0.000
I33 Acute and subacute endocarditis
0.774 0.226 0.000
R19.5 Other fecal abnormalities
0.774 0.226 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.771 0.229 0.000
Y44 Agents primarily affecting blood constituents
0.771 0.229 0.000
M21 Other acquired deformities of limbs
0.771 0.229 0.000
I77 Other disorders of arteries and arterioles
0.769 0.231 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.767 0.233 0.000
M06 Other rheumatoid arthritis
0.766 0.233 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.766 0.234 0.000
T93.1 Sequelae of fracture of femur
0.765 0.235 0.000
I12 Hypertensive renal disease
0.764 0.236 0.000
I71 Aortic aneurysm and dissection
0.764 0.236 0.000
K35-K38 Diseases of appendix
0.764 0.236 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.763 0.237 0.000
Q61 Cystic kidney disease
0.762 0.238 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.762 0.238 0.000
E10.1 With ketoacidosis
0.761 0.239 0.000
I62 Other nontraumatic intracranial haemorrhage
0.759 0.241 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.759 0.241 0.000
K21 Gastro-oesophageal reflux disease
0.757 0.243 0.000
M54 Dorsalgia
0.757 0.243 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.757 0.243 0.000
I11 Hypertensive heart disease
0.752 0.248 0.000
S00-S09 Injuries to the head
0.752 0.248 0.000
R50 Fever of unknown origin
0.751 0.248 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.750 0.250 0.000
H18 Other disorders of cornea
0.750 0.250 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.749 0.251 0.000
I67.8 Other specified cerebrovascular diseases
0.749 0.251 0.000
S70-S79 Injuries to the hip and thigh
0.749 0.251 0.000
I63 Cerebral infarction
0.747 0.253 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.746 0.253 0.000
I35.1 Aortic (valve) insufficiency
0.745 0.255 0.000
K70-K77 Diseases of liver
0.741 0.259 0.000
S80-S89 Injuries to the knee and lower leg
0.740 0.260 0.000
N21 Calculus of lower urinary tract
0.740 0.260 0.000
D70 Agranulocytosis
0.739 0.261 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.739 0.261 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.739 0.261 0.000
L40.9 Psoriasis, unspecified
0.738 0.262 0.000
F60-F69 Disorders of adult personality and behaviour
0.738 0.262 0.000
L40.5 Arthropathic psoriasis
0.737 0.263 0.000
M07 Psoriatic and enteropathic arthropathies
0.736 0.264 0.000
R15 Faecal incontinence
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.736 0.264 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.735 0.264 0.000
B15-B19 Viral hepatitis
0.734 0.266 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.734 0.266 0.000
S36 Injury of intra-abdominal organs
0.732 0.268 0.000
A80-A89 Viral infections of the central nervous system
0.732 0.268 0.000
T93.2 Sequelae of other fractures of lower limb
0.732 0.268 0.000
R59.0 Localised enlarged lymph nodes
0.732 0.268 0.000
G90 Disorders of autonomic nervous system
0.732 0.268 0.000
H30-H36 Disorders of choroid and retina
0.731 0.269 0.000
M86-M90 Other osteopathies
0.730 0.270 0.000
D75 Other diseases of blood and blood-forming organs
0.730 0.270 0.000
Y40.8 Other systemic antibiotics
0.730 0.270 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.729 0.271 0.000
B34 Viral infection of unspecified site
0.729 0.271 0.000
T42.4 Benzodiazepines
0.729 0.271 0.000
F31.9 Bipolar affective disorder, unspecified
0.728 0.272 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.727 0.273 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.726 0.274 0.000
A40 Streptococcal septicaemia
0.726 0.274 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.725 0.275 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.724 0.276 0.000
H46 Optic neuritis
0.723 0.277 0.000
M18 Arthrosis of first carpometacarpal joint
0.722 0.278 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.722 0.278 0.000
H04 Disorders of lachrymal system
0.721 0.279 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.721 0.279 0.000
G60 Hereditary and idiopathic neuropathy
0.721 0.279 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.721 0.279 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.721 0.279 0.000
I24.8 Other forms of acute ischaemic heart disease
0.720 0.280 0.000
M50.1 Cervical disk disorder with radiculopathy
0.720 0.280 0.000
S50-S59 Injuries to the elbow and forearm
0.719 0.281 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.717 0.283 0.000
H47.2 Optic atrophy
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I46 Cardiac arrest
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
E86 Volume depletion
0.716 0.284 0.000
R18 Ascites
0.715 0.285 0.000
I72 Other aneurysm
0.715 0.285 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.714 0.286 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.714 0.286 0.000
G20-G26 Extrapyramidal and movement disorders
0.714 0.286 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.713 0.287 0.000
G62.0 Drug-induced polyneuropathy
0.712 0.288 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.712 0.288 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.711 0.289 0.000
I20.0 Unstable angina
0.710 0.290 0.000
I69 Sequelae of cerebrovascular disease
0.710 0.290 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.710 0.290 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.709 0.291 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.708 0.292 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.707 0.293 0.000
I23 Certain current complications following acute myocardial infarction
0.707 0.293 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
I31 Other diseases of pericardium
0.706 0.294 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.706 0.294 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.706 0.294 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.706 0.294 0.000
E50-E64 Other nutritional deficiencies
0.706 0.294 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.706 0.294 0.000
Y43.4 Immunosuppressive agents
0.706 0.294 0.000
G96.0 Cerebrospinal fluid leak
0.705 0.295 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.703 0.297 0.000
M80-M85 Disorders of bone density and structure
0.702 0.298 0.000
H50.1 Divergent concomitant strabismus
0.702 0.298 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.701 0.299 0.000
T95 Sequelae of burns, corrosions and frostbite
0.701 0.299 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.701 0.299 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.701 0.299 0.000
D50-D53 Nutritional anaemias
0.701 0.299 0.000
I22 Subsequent myocardial infarction
0.701 0.299 0.000
H20 Iridocyclitis
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.700 0.300 0.000
Y10-Y34 Event of undetermined intent
0.700 0.300 0.000
Y00-Y09 Assault
0.700 0.300 0.000
X85-X99 Assault
0.700 0.300 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.700 0.300 0.000
X30-X39 Exposure to forces of nature
0.700 0.300 0.000
X20-X29 Contact with venomous animals and plants
0.700 0.300 0.000
X10-X19 Contact with heat and hot substances
0.700 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.700 0.300 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
W65-W74 Accidental drowning and submersion
0.700 0.300 0.000
W50-W64 Exposure to animate mechanical forces
0.700 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.700 0.300 0.000
V95-V97 Air and space transport accidents
0.700 0.300 0.000
V90-V94 Water transport accidents
0.700 0.300 0.000
V80-V89 Other land transport accidents
0.700 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.700 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.700 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
V40-V49 Car occupant injured in transport accident
0.700 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.700 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.700 0.300 0.000
H52 Disorders of refraction and accommodation
0.699 0.301 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.698 0.302 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.698 0.302 0.000
B65-B83 Helminthiases
0.698 0.302 0.000
B50-B64 Protozoal diseases
0.698 0.302 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.698 0.302 0.000
A75-A79 Rickettsioses
0.698 0.302 0.000
A70-A74 Other diseases caused by chlamydiae
0.698 0.302 0.000
A65-A69 Other spirochaetal diseases
0.698 0.302 0.000
A20-A28 Certain zoonotic bacterial diseases
0.698 0.302 0.000
A15-A19 Tuberculosis
0.698 0.302 0.000
M65-M68 Disorders of synovium and tendon
0.698 0.302 0.000
I30.9 Acute pericarditis, unspecified
0.697 0.303 0.000
E12 Malnutrition-related diabetes mellitus
0.696 0.304 0.000
G93.6 Cerebral oedema
0.696 0.304 0.000
L60-L75 Disorders of skin appendages
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
I38 Endocarditis, valve unspecified
0.694 0.306 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.694 0.306 0.000
M24 Other specific joint derangements
0.693 0.306 0.000
E10.8 With unspecified complications
0.693 0.307 0.000
E10.7 With multiple complications
0.693 0.307 0.000
E10.6 With other specified complications
0.693 0.307 0.000
E10.0 With coma
0.693 0.307 0.000
E85 Amyloidosis
0.693 0.307 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.693 0.307 0.000
I74 Arterial embolism and thrombosis
0.693 0.307 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.692 0.308 0.000
N20.9 Urinary calculus, unspecified
0.692 0.308 0.000
Q61.2 Polycystic kidney, adult type
0.692 0.308 0.000
B35 Dermatophytosis
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.690 0.310 0.000
I25.3 Aneurysm of heart
0.690 0.310 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
E20-E35 Disorders of other endocrine glands
0.690 0.310 0.000
F30 Manic episode
0.689 0.311 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.689 0.311 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.688 0.312 0.000
G61 Inflammatory polyneuropathy
0.688 0.312 0.000
H72 Perforation of tympanic membrane
0.687 0.313 0.000
K31.5 Obstruction of duodenum
0.687 0.313 0.000
N28.8 Other specified disorders of kidney and ureter
0.687 0.313 0.000
I44 Atrioventricular and left bundle-branch block
0.686 0.314 0.000
Y52 Agents primarily affecting the cardiovascular system
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.685 0.315 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.685 0.315 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.685 0.315 0.000
G92 Toxic encephalopathy
0.685 0.315 0.000
R56 Convulsions, not elsewhere classified
0.684 0.315 0.000
E87.7 Fluid overload
0.684 0.315 0.000
G93.8 Other specified disorders of brain
0.684 0.316 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.684 0.316 0.000
M23 Internal derangement of knee
0.684 0.316 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
E11 Non-insulin-dependent diabetes mellitus
0.683 0.317 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.683 0.317 0.000
B37.0 Candidal stomatitis
0.682 0.317 0.000
H53-H54 Visual disturbances and blindness
0.682 0.318 0.000
S67 Crushing injury of wrist and hand
0.682 0.318 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.682 0.318 0.000
H65 Nonsuppurative otitis media
0.681 0.319 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.680 0.320 0.000
N18.4 Chronic kidney disease, stage 4
0.679 0.321 0.000
K25.3 Acute without haemorrhage or perforation
0.679 0.321 0.000
I15.1 Hypertension secondary to other renal disorders
0.679 0.321 0.000
S32 Fracture of lumbar spine and pelvis
0.678 0.322 0.000
R10.3 Pain localised to other parts of lower abdomen
0.677 0.323 0.000
M54.3 Sciatica
0.677 0.323 0.000
G64 Other disorders of peripheral nervous system
0.676 0.323 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.676 0.324 0.000
S09 Other and unspecified injuries of head
0.676 0.324 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.676 0.324 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.324 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.676 0.324 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.676 0.324 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.676 0.324 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.676 0.324 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.676 0.324 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.676 0.324 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
T36 Poisoning by systemic antibiotics
0.676 0.324 0.000
Y59 Other and unspecified vaccines and biological substances
0.676 0.324 0.000
Y58 Bacterial vaccines
0.676 0.324 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.676 0.324 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.324 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.676 0.324 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.676 0.324 0.000
Y48 Anaesthetics and therapeutic gases
0.676 0.324 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.676 0.324 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.676 0.324 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.675 0.324 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.675 0.325 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.675 0.325 0.000
F80-F89 Disorders of psychological development
0.675 0.325 0.000
F70-F79 Mental retardation
0.675 0.325 0.000
I05-I09 Chronic rheumatic heart diseases
0.675 0.325 0.000
B48 Other mycoses, not elsewhere classified
0.674 0.326 0.000
B47 Mycetoma
0.674 0.326 0.000
B46 Zygomycosis
0.674 0.326 0.000
B45 Cryptococcosis
0.674 0.326 0.000
B44 Aspergillosis
0.674 0.326 0.000
B43 Chromomycosis and phaeomycotic abscess
0.674 0.326 0.000
B42 Sporotrichosis
0.674 0.326 0.000
B41 Paracoccidioidomycosis
0.674 0.326 0.000
B40 Blastomycosis
0.674 0.326 0.000
B39 Histoplasmosis
0.674 0.326 0.000
B38 Coccidioidomycosis
0.674 0.326 0.000
B36 Other superficial mycoses
0.674 0.326 0.000
B49 Unspecified mycosis
0.674 0.326 0.000
A46 Erysipelas
0.673 0.327 0.000
N18.0 End-stage renal disease
0.673 0.327 0.000
I47 Paroxysmal tachycardia
0.673 0.327 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.672 0.327 0.000
Q00-Q07 Congenital malformations of the nervous system
0.672 0.327 0.000
M62 Other disorders of muscle
0.672 0.327 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.672 0.328 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.328 0.000
I33.0 Acute and subacute infective endocarditis
0.671 0.329 0.000
N18.8 Other chronic renal failure
0.670 0.330 0.000
N18.1 Chronic kidney disease, stage 1
0.670 0.330 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.668 0.332 0.000
G70-G73 Diseases of myoneural junction and muscle
0.668 0.332 0.000
I12.0 Hypertensive renal disease with renal failure
0.668 0.332 0.000
F02 Dementia in other diseases classified elsewhere
0.667 0.332 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.666 0.334 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
Y95 Nosocomial condition
0.666 0.334 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.665 0.335 0.000
S42.1 Fracture of scapula
0.665 0.335 0.000
E87.6 Hypokalaemia
0.665 0.335 0.000
B99 Other and unspecified infectious diseases
0.665 0.335 0.000
T20 Burn and corrosion of head and neck
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.337 0.000
Y57 Other and unspecified drugs and medicaments
0.663 0.337 0.000
D75.1 Secondary polycythaemia
0.663 0.337 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.662 0.338 0.000
Q50-Q56 Congenital malformations of genital organs
0.662 0.338 0.000
Q35-Q37 Cleft lip and cleft palate
0.662 0.338 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.662 0.338 0.000
M17.0 Primary gonarthrosis, bilateral
0.662 0.338 0.000
E13 Other specified diabetes mellitus
0.661 0.339 0.000
S90-S99 Injuries to the ankle and foot
0.661 0.339 0.000
S40 Superficial injury of shoulder and upper arm
0.661 0.339 0.000
K27 Peptic ulcer, site unspecified
0.660 0.340 0.000
M06.9 Rheumatoid arthritis, unspecified
0.660 0.340 0.000
I52 Other heart disorders in diseases classified elsewhere
0.658 0.342 0.000
I48 Atrial fibrillation and flutter
0.658 0.342 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.658 0.342 0.000
I41 Myocarditis in diseases classified elsewhere
0.658 0.342 0.000
I40 Acute myocarditis
0.658 0.342 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.658 0.342 0.000
I37 Pulmonary valve disorders
0.658 0.342 0.000
I36 Nonrheumatic tricuspid valve disorders
0.658 0.342 0.000
I32 Pericarditis in diseases classified elsewhere
0.658 0.342 0.000
G35 Multiple sclerosis
0.657 0.343 0.000
I45 Other conduction disorders
0.657 0.343 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.657 0.343 0.000
I50 Heart failure
0.656 0.344 0.000
T92 Sequelae of injuries of upper limb
0.656 0.344 0.000
B34.9 Viral infection, unspecified
0.656 0.344 0.000
I13 Hypertensive heart and renal disease
0.656 0.344 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.656 0.344 0.000
B37.7 Candidal septicaemia
0.655 0.345 0.000
B37.6 Candidal endocarditis
0.655 0.345 0.000
B37.5 Candidal meningitis
0.655 0.345 0.000
B37.4 Candidiasis of other urogenital sites
0.655 0.345 0.000
B37.2 Candidiasis of skin and nail
0.655 0.345 0.000
B37.1 Pulmonary candidiasis
0.655 0.345 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.654 0.345 0.000
E87.2 Acidosis
0.654 0.346 0.000
T86.1 Kidney transplant failure and rejection
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.654 0.346 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.654 0.346 0.000
I20.1 Angina pectoris with documented spasm
0.653 0.347 0.000
R16.1 Splenomegaly, not elsewhere classified
0.653 0.347 0.000
I35.0 Aortic (valve) stenosis
0.653 0.347 0.000
T91.3 Sequelae of injury of spinal cord
0.653 0.347 0.000
I70 Atherosclerosis
0.653 0.347 0.000
K28 Gastrojejunal ulcer
0.653 0.347 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.653 0.347 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.653 0.347 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.653 0.347 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.653 0.347 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.653 0.347 0.000
T93.0 Sequelae of open wound of lower limb
0.653 0.347 0.000
M14 Arthropathies in other diseases classified elsewhere
0.653 0.347 0.000
M12 Other specific arthropathies
0.653 0.347 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.653 0.347 0.000
M08 Juvenile arthritis
0.653 0.347 0.000
R50.0 Fever with chills
0.652 0.348 0.000
R68 Other general symptoms and signs
0.652 0.348 0.000
S19 Other and unspecified injuries of neck
0.652 0.348 0.000
B37.3 Candidiasis of vulva and vagina
0.651 0.349 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.651 0.349 0.000
S48 Traumatic amputation of shoulder and upper arm
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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