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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73167108
log Bayes Factor = 11.234
Chromosome 3   position 166,673,121  (GRCh37) Explore rs73167108 on Ensembl!
Variant rs73167108 is part of Cluster X0165

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.991 0.009 0.000
K50-K52 Noninfective enteritis and colitis
0.991 0.009 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.990 0.010 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.989 0.011 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
K51 Ulcerative colitis
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
Z95.1 Presence of aortocoronary bypass graft
0.985 0.015 0.000
K40-K46 Hernia
0.984 0.016 0.000
K43 Ventral hernia
0.981 0.019 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.978 0.022 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.978 0.022 0.000
K51.9 Ulcerative colitis, unspecified
0.973 0.027 0.000
S00-S09 Injuries to the head
0.963 0.037 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.961 0.039 0.000
Chapter II Neoplasms
0.960 0.040 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.957 0.043 0.000
F30-F39 Mood [affective] disorders
0.955 0.045 0.000
Chapter XX External causes of morbidity and mortality
0.949 0.051 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.947 0.053 0.000
S60-S69 Injuries to the wrist and hand
0.947 0.053 0.000
Z93 Artificial opening status
0.944 0.056 0.000
O00-O08 Pregnancy with abortive outcome
0.944 0.056 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.944 0.056 0.000
C15-C26 Malignant neoplasms of digestive organs
0.942 0.058 0.000
K65-K67 Diseases of peritoneum
0.941 0.059 0.000
G40-G47 Episodic and paroxysmal disorders
0.939 0.061 0.000
F41 Other anxiety disorders
0.936 0.064 0.000
F32 Depressive episode
0.932 0.068 0.000
Z94 Transplanted organ and tissue status
0.929 0.071 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.925 0.075 0.000
F41.2 Mixed anxiety and depressive disorder
0.924 0.076 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.921 0.079 0.000
S01 Open wound of head
0.920 0.080 0.000
G40 Epilepsy
0.920 0.080 0.000
F32.9 Depressive episode, unspecified
0.918 0.082 0.000
T81 Complications of procedures, not elsewhere classified
0.913 0.087 0.000
S40-S49 Injuries to the shoulder and upper arm
0.913 0.087 0.000
K55-K64 Other diseases of intestines
0.909 0.091 0.000
C20 Malignant neoplasm of rectum
0.909 0.091 0.000
S01.0 Open wound of scalp
0.907 0.093 0.000
O60-O75 Complications of labour and delivery
0.907 0.093 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.902 0.098 0.000
M45-M49 Spondylopathies
0.901 0.099 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.901 0.099 0.000
O02 Other abnormal products of conception
0.900 0.100 0.000
Z95.2 Presence of prosthetic heart valve
0.897 0.103 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.895 0.105 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.891 0.109 0.000
K60 Fissure and fistula of anal and rectal regions
0.889 0.111 0.000
K51.8 Other ulcerative colitis
0.886 0.114 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.885 0.115 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.885 0.115 0.000
K66 Other disorders of peritoneum
0.879 0.121 0.000
G40.9 Epilepsy, unspecified
0.876 0.124 0.000
C21 Malignant neoplasm of anus and anal canal
0.875 0.125 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.873 0.127 0.000
S62 Fracture at wrist and hand level
0.871 0.129 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.869 0.131 0.000
S90-S99 Injuries to the ankle and foot
0.868 0.132 0.000
O02.1 Missed abortion
0.868 0.132 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.866 0.134 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.866 0.134 0.000
Z95.4 Presence of other heart-valve replacement
0.864 0.136 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.861 0.139 0.000
Y84.8 Other medical procedures
0.855 0.145 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.853 0.147 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.851 0.149 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.849 0.151 0.000
Z93.1 Gastrostomy status
0.849 0.151 0.000
C64-C68 Malignant neoplasms of urinary tract
0.847 0.153 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.846 0.154 0.000
S01.1 Open wound of eyelid and periocular area
0.844 0.156 0.000
G35 Multiple sclerosis
0.843 0.157 0.000
K41 Femoral hernia
0.843 0.157 0.000
T82.3 Mechanical complication of other vascular grafts
0.843 0.157 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.842 0.158 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.842 0.158 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.838 0.162 0.000
K56.6 Other and unspecified intestinal obstruction
0.838 0.162 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.837 0.163 0.000
S20-S29 Injuries to the thorax
0.836 0.164 0.000
M50-M54 Other dorsopathies
0.834 0.166 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.834 0.166 0.000
S05 Injury of eye and orbit
0.833 0.167 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.832 0.168 0.000
T82.1 Mechanical complication of cardiac electronic device
0.831 0.169 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.831 0.169 0.000
Z89 Acquired absence of limb
0.830 0.170 0.000
T86 Failure and rejection of transplanted organs and tissues
0.829 0.170 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.829 0.171 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.828 0.171 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.828 0.172 0.000
C21.0 Anus, unspecified
0.828 0.172 0.000
S65 Injury of blood vessels at wrist and hand level
0.826 0.174 0.000
M47 Spondylosis
0.825 0.175 0.000
K51.2 Ulcerative (chronic) proctitis
0.825 0.175 0.000
K66.0 Peritoneal adhesions
0.825 0.175 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.825 0.175 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.823 0.177 0.000
D45 Polycythaemia vera
0.822 0.178 0.000
Z90.8 Acquired absence of other organs
0.821 0.179 0.000
Z98 Other postsurgical states
0.821 0.179 0.000
Z86 Personal history of certain other diseases
0.820 0.180 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.820 0.180 0.000
M40-M43 Deforming dorsopathies
0.820 0.180 0.000
G51 Facial nerve disorders
0.818 0.182 0.000
Z93.0 Tracheostomy status
0.816 0.184 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.814 0.186 0.000
Z93.2 Ileostomy status
0.810 0.190 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.809 0.191 0.000
Z94.0 Kidney transplant status
0.806 0.194 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.803 0.197 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.802 0.198 0.000
K60.3 Anal fistula
0.800 0.200 0.000
M47.9 Spondylosis, unspecified
0.798 0.202 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.796 0.204 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.794 0.206 0.000
M60-M63 Disorders of muscles
0.793 0.207 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.792 0.208 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.790 0.210 0.000
M48 Other spondylopathies
0.790 0.210 0.000
K60.2 Anal fissure, unspecified
0.789 0.211 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.789 0.211 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.789 0.211 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.788 0.212 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.788 0.212 0.000
Z43 Attention to artificial openings
0.787 0.213 0.000
O48 Prolonged pregnancy
0.787 0.213 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.787 0.213 0.000
G70-G73 Diseases of myoneural junction and muscle
0.785 0.215 0.000
G51.0 Bell's palsy
0.785 0.215 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.782 0.218 0.000
O43 Placental disorders
0.782 0.218 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.780 0.220 0.000
M86-M90 Other osteopathies
0.776 0.224 0.000
F33 Recurrent depressive disorder
0.774 0.226 0.000
Q80-Q89 Other congenital malformations
0.772 0.228 0.000
Z94.8 Other transplanted organ and tissue status
0.770 0.230 0.000
K65 Peritonitis
0.769 0.231 0.000
T87 Complications peculiar to reattachment and amputation
0.769 0.231 0.000
Z43.2 Attention to ileostomy
0.768 0.232 0.000
M80-M85 Disorders of bone density and structure
0.767 0.233 0.000
G41 Status epilepticus
0.765 0.235 0.000
C71 Malignant neoplasm of brain
0.763 0.237 0.000
Z99.2 Dependence on renal dialysis
0.763 0.237 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.762 0.238 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.762 0.238 0.000
S42 Fracture of shoulder and upper arm
0.760 0.239 0.000
O36 Maternal care for other known or suspected foetal problems
0.759 0.241 0.000
S92 Fracture of foot, except ankle
0.758 0.242 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.757 0.243 0.000
S06 Intracranial injury
0.756 0.244 0.000
Z90.5 Acquired absence of kidney
0.756 0.244 0.000
X60-X84 Intentional self-harm
0.754 0.246 0.000
K60.0 Acute anal fissure
0.754 0.246 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.754 0.246 0.000
M51 Other intervertebral disk disorders
0.753 0.247 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.752 0.248 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.751 0.249 0.000
Z45 Adjustment and management of implanted device
0.751 0.249 0.000
Z94.1 Heart transplant status
0.749 0.251 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.748 0.252 0.000
O00 Ectopic pregnancy
0.747 0.253 0.000
F42 Obsessive-compulsive disorder
0.747 0.253 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.746 0.254 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.746 0.254 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.746 0.254 0.000
D60-D64 Aplastic and other anaemias
0.746 0.254 0.000
G47 Sleep disorders
0.744 0.256 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.742 0.258 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.741 0.259 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.741 0.259 0.000
S65.5 Injury of blood vessel(s) of other finger
0.739 0.261 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.739 0.261 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.738 0.262 0.000
S02 Fracture of skull and facial bones
0.738 0.262 0.000
O63 Long labour
0.736 0.264 0.000
O42 Premature rupture of membranes
0.735 0.265 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.734 0.266 0.000
O41 Other disorders of amniotic fluid and membranes
0.734 0.266 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
F41.1 Generalised anxiety disorder
0.731 0.269 0.000
F32.1 Moderate depressive episode
0.731 0.269 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.731 0.269 0.000
K45 Other abdominal hernia
0.729 0.271 0.000
Z89.4 Acquired absence of foot and ankle
0.727 0.273 0.000
O85-O92 Complications predominantly related to the puerperium
0.727 0.273 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.726 0.274 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.724 0.276 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.724 0.276 0.000
O61 Failed induction of labour
0.723 0.276 0.000
S10-S19 Injuries to the neck
0.723 0.277 0.000
O47 False labour
0.723 0.277 0.000
Z32 Pregnancy examination and test
0.723 0.277 0.000
G44 Other headache syndromes
0.723 0.277 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.723 0.277 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.722 0.277 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.722 0.277 0.000
K50 Crohn's disease [regional enteritis]
0.722 0.278 0.000
Z95.3 Presence of xenogenic heart valve
0.721 0.279 0.000
T66-T78 Other and unspecified effects of external causes
0.720 0.280 0.000
Chapter VIII Diseases of the ear and mastoid process
0.720 0.280 0.000
Q50-Q56 Congenital malformations of genital organs
0.719 0.281 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.719 0.281 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.718 0.282 0.000
Z45.8 Adjustment and management of other implanted devices
0.718 0.282 0.000
C51-C58 Malignant neoplasms of female genital organs
0.718 0.282 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.717 0.283 0.000
Q60-Q64 Congenital malformations of the urinary system
0.716 0.284 0.000
Z43.1 Attention to gastrostomy
0.716 0.284 0.000
O32.0 Maternal care for unstable lie
0.715 0.285 0.000
G90-G99 Other disorders of the nervous system
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
O62 Abnormalities of forces of labour
0.711 0.289 0.000
F40 Phobic anxiety disorders
0.711 0.289 0.000
Z33 Pregnant state, incidental
0.711 0.289 0.000
K65.0 Acute peritonitis
0.711 0.289 0.000
M48.0 Spinal stenosis
0.710 0.290 0.000
Z84 Family history of other conditions
0.709 0.290 0.000
Z81 Family history of mental and behavioural disorders
0.709 0.290 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
K51.5 Mucosal proctocolitis
0.708 0.292 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.708 0.292 0.000
Z94.7 Corneal transplant status
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.707 0.293 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.293 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.706 0.294 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.706 0.294 0.000
K61 Abscess of anal and rectal regions
0.706 0.294 0.000
F43 Reaction to severe stress, and adjustment disorders
0.706 0.294 0.000
Q43 Other congenital malformations of intestine
0.705 0.295 0.000
O44 Placenta praevia
0.705 0.295 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.705 0.295 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.705 0.295 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.703 0.297 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.703 0.297 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.703 0.297 0.000
K43.4 Parastomal hernia with gangrene
0.703 0.297 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.703 0.297 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.703 0.297 0.000
K43.1 Ventral hernia with gangrene
0.703 0.297 0.000
S05.8 Other injuries of eye and orbit
0.702 0.298 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.701 0.299 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.701 0.299 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.701 0.299 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.701 0.299 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.701 0.299 0.000
K55 Vascular disorders of intestine
0.700 0.300 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.699 0.301 0.000
C32 Malignant neoplasm of larynx
0.699 0.301 0.000
D75 Other diseases of blood and blood-forming organs
0.698 0.302 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.698 0.302 0.000
S69 Other and unspecified injuries of wrist and hand
0.697 0.303 0.000
M91-M94 Chondropathies
0.697 0.303 0.000
Y52 Agents primarily affecting the cardiovascular system
0.696 0.304 0.000
K46 Unspecified abdominal hernia
0.696 0.304 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.304 0.000
F60-F69 Disorders of adult personality and behaviour
0.695 0.305 0.000
S62.5 Fracture of thumb
0.695 0.305 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.694 0.306 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.693 0.307 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.693 0.307 0.000
M41 Scoliosis
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
Q00-Q07 Congenital malformations of the nervous system
0.691 0.308 0.000
S62.6 Fracture of other finger
0.690 0.309 0.000
S08 Traumatic amputation of part of head
0.690 0.310 0.000
S07 Crushing injury of head
0.690 0.310 0.000
S04 Injury of cranial nerves
0.690 0.310 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.690 0.310 0.000
D64 Other anaemias
0.689 0.311 0.000
T91 Sequelae of injuries of neck and trunk
0.689 0.311 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.689 0.311 0.000
Y43 Primarily systemic agents
0.689 0.311 0.000
F48 Other neurotic disorders
0.689 0.311 0.000
F44 Dissociative [conversion] disorders
0.689 0.311 0.000
K60.5 Anorectal fistula
0.688 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.312 0.000
O45 Premature separation of placenta [abruptio placentae]
0.686 0.314 0.000
O33 Maternal care for known or suspected disproportion
0.686 0.314 0.000
O31 Complications specific to multiple gestation
0.686 0.314 0.000
O40 Polyhydramnios
0.686 0.314 0.000
M00-M03 Infectious arthropathies
0.686 0.314 0.000
K56.4 Other impaction of intestine
0.685 0.315 0.000
F38 Other mood [affective] disorders
0.685 0.315 0.000
F34 Persistent mood [affective] disorders
0.685 0.315 0.000
F30 Manic episode
0.685 0.315 0.000
F39 Unspecified mood [affective] disorder
0.685 0.315 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.683 0.317 0.000
G61 Inflammatory polyneuropathy
0.682 0.318 0.000
M62 Other disorders of muscle
0.682 0.318 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.682 0.318 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
Y00-Y09 Assault
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V80-V89 Other land transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
O04 Medical abortion
0.679 0.321 0.000
F99-F99 Unspecified mental disorder
0.678 0.321 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.678 0.322 0.000
S62.7 Multiple fractures of fingers
0.678 0.322 0.000
C25 Malignant neoplasm of pancreas
0.678 0.322 0.000
K66.8 Other specified disorders of peritoneum
0.678 0.322 0.000
Z93.9 Artificial opening status, unspecified
0.677 0.323 0.000
Z93.8 Other artificial opening status
0.677 0.323 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.677 0.323 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.677 0.323 0.000
O07 Failed attempted abortion
0.677 0.323 0.000
O06 Unspecified abortion
0.677 0.323 0.000
O05 Other abortion
0.677 0.323 0.000
O01 Hydatidiform mole
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.677 0.323 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.677 0.323 0.000
S09 Other and unspecified injuries of head
0.676 0.324 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.675 0.324 0.000
C17 Malignant neoplasm of small intestine
0.675 0.324 0.000
C23 Malignant neoplasm of gallbladder
0.675 0.324 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.675 0.325 0.000
G51.3 Clonic hemifacial spasm
0.674 0.326 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.673 0.327 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.672 0.328 0.000
S91 Open wound of ankle and foot
0.672 0.328 0.000
F41.8 Other specified anxiety disorders
0.671 0.329 0.000
F41.3 Other mixed anxiety disorders
0.671 0.329 0.000
Z93.3 Colostomy status
0.671 0.329 0.000
C60-C63 Malignant neoplasms of male genital organs
0.670 0.330 0.000
G47.9 Sleep disorder, unspecified
0.670 0.330 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.669 0.331 0.000
M89 Other disorders of bone
0.668 0.331 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.668 0.332 0.000
F32.8 Other depressive episodes
0.668 0.332 0.000
F32.0 Mild depressive episode
0.668 0.332 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.668 0.332 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.668 0.332 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.668 0.332 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.668 0.332 0.000
S20 Superficial injury of thorax
0.667 0.333 0.000
S27 Injury of other and unspecified intrathoracic organs
0.667 0.333 0.000
O36.8 Maternal care for other specified foetal problems
0.667 0.333 0.000
Z90.0 Acquired absence of part of head and neck
0.666 0.333 0.000
O66 Other obstructed labour
0.666 0.333 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.666 0.334 0.000
S62.2 Fracture of first metacarpal bone
0.666 0.334 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.666 0.334 0.000
Z94.6 Bone transplant status
0.666 0.334 0.000
Z94.5 Skin transplant status
0.666 0.334 0.000
Z94.3 Heart and lungs transplant status
0.666 0.334 0.000
Z94.2 Lung transplant status
0.666 0.334 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.666 0.334 0.000
S05.1 Contusion of eyeball and orbital tissues
0.666 0.334 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.666 0.334 0.000
D73 Diseases of spleen
0.665 0.335 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.663 0.336 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.663 0.337 0.000
Z43.0 Attention to tracheostomy
0.663 0.337 0.000
M15-M19 Arthrosis
0.663 0.337 0.000
Z94.4 Liver transplant status
0.662 0.338 0.000
Y57 Other and unspecified drugs and medicaments
0.662 0.338 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.661 0.339 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.661 0.339 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.661 0.339 0.000
T90 Sequelae of injuries of head
0.660 0.340 0.000
S01.7 Multiple open wounds of head
0.660 0.340 0.000
G40.8 Other epilepsy
0.660 0.340 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.660 0.340 0.000
G40.5 Special epileptic syndromes
0.660 0.340 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.660 0.340 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.660 0.340 0.000
Z99.1 Dependence on respirator
0.659 0.341 0.000
M50 Cervical disk disorders
0.656 0.344 0.000
K42 Umbilical hernia
0.655 0.345 0.000
Z93.5 Cystostomy status
0.655 0.345 0.000
G51.9 Disorder of facial nerve, unspecified
0.655 0.345 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.655 0.345 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.655 0.345 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.655 0.345 0.000
S48 Traumatic amputation of shoulder and upper arm
0.655 0.345 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.655 0.345 0.000
S44 Injury of nerves at shoulder and upper arm level
0.655 0.345 0.000
S41 Open wound of shoulder and upper arm
0.655 0.345 0.000
S47 Crushing injury of shoulder and upper arm
0.655 0.345 0.000
Y84.6 Urinary catheterisation
0.654 0.346 0.000
T81.9 Unspecified complication of procedure
0.653 0.347 0.000
M43 Other deforming dorsopathies
0.653 0.347 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.653 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.652 0.348 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.652 0.348 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.652 0.348 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.651 0.349 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.651 0.349 0.000
O74 Complications of anaesthesia during labour and delivery
0.650 0.350 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.650 0.350 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.650 0.350 0.000
O60 Preterm delivery
0.650 0.350 0.000
D80-D89 Certain disorders involving the immune mechanism
0.650 0.350 0.000
O63.1 Prolonged second stage (of labour)
0.650 0.350 0.000
Z35 Supervision of high-risk pregnancy
0.649 0.351 0.000
D64.9 Anaemia, unspecified
0.649 0.351 0.000
O43.1 Malformation of placenta
0.649 0.351 0.000
C71.4 Occipital lobe
0.649 0.351 0.000
S64 Injury of nerves at wrist and hand level
0.649 0.351 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.648 0.351 0.000
M45 Ankylosing spondylitis
0.648 0.352 0.000
S40 Superficial injury of shoulder and upper arm
0.648 0.352 0.000
O32.8 Maternal care for other malpresentation of foetus
0.647 0.353 0.000
M46 Other inflammatory spondylopathies
0.647 0.353 0.000
G36 Other acute disseminated demyelination
0.646 0.353 0.000
M49 Spondylopathies in diseases classified elsewhere
0.646 0.354 0.000
Z95.0 Presence of cardiac pacemaker
0.646 0.354 0.000
C66 Malignant neoplasm of ureter
0.646 0.354 0.000
Z99.3 Dependence on wheelchair
0.646 0.354 0.000
O02.9 Abnormal product of conception, unspecified
0.645 0.355 0.000
O02.8 Other specified abnormal products of conception
0.645 0.355 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.645 0.355 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.644 0.356 0.000
Z93.6 Other artificial openings of urinary tract status
0.644 0.356 0.000
K60.1 Chronic anal fissure
0.643 0.357 0.000
Q82 Other congenital malformations of skin
0.643 0.357 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.642 0.358 0.000
Z57 Occupational exposure to risk-factors
0.642 0.358 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.642 0.358 0.000
D55-D59 Haemolytic anaemias
0.642 0.358 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.641 0.358 0.000
M51.9 Intervertebral disk disorder, unspecified
0.641 0.359 0.000
S70-S79 Injuries to the hip and thigh
0.641 0.359 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.640 0.360 0.000
K51.4 Pseudopolyposis of colon
0.640 0.360 0.000
G41.9 Status epilepticus, unspecified
0.640 0.360 0.000
M20-M25 Other joint disorders
0.639 0.361 0.000
C34 Malignant neoplasm of bronchus and lung
0.638 0.361 0.000
G37 Other demyelinating diseases of central nervous system
0.638 0.362 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.637 0.363 0.000
K60.4 Rectal fistula
0.637 0.363 0.000
T92 Sequelae of injuries of upper limb
0.637 0.363 0.000
S01.4 Open wound of cheek and temporomandibular area
0.636 0.364 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.636 0.364 0.000
Z43.8 Attention to other artificial openings
0.636 0.364 0.000
Y84.1 Kidney dialysis
0.636 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.635 0.365 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.635 0.365 0.000
Z49 Care involving dialysis
0.635 0.365 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.635 0.365 0.000
T86.1 Kidney transplant failure and rejection
0.635 0.365 0.000
K56.3 Gallstone ileus
0.634 0.365 0.000
K56.0 Paralytic ileus
0.634 0.365 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.634 0.366 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.634 0.366 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.632 0.368 0.000
O73 Retained placenta and membranes, without haemorrhage
0.632 0.368 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.631 0.368 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.631 0.369 0.000
O03 Spontaneous abortion
0.631 0.369 0.000
S42.3 Fracture of shaft of humerus
0.631 0.369 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.631 0.369 0.000
K66.9 Disorder of peritoneum, unspecified
0.630 0.369 0.000
K66.1 Haemoperitoneum
0.630 0.369 0.000
K55.2 Angiodysplasia of colon
0.630 0.370 0.000
G58 Other mononeuropathies
0.630 0.370 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.629 0.371 0.000
Z32.1 Pregnancy confirmed
0.629 0.371 0.000
Z90.2 Acquired absence of lung [part of]
0.628 0.371 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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