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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73180929
log Bayes Factor = 14.6825
Chromosome 13   position 44,804,303  (GRCh37) Explore rs73180929 on Ensembl!
Variant rs73180929 is part of Cluster X0055

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
K29 Gastritis and duodenitis
0.995 0.005 0.000
K31 Other diseases of stomach and duodenum
0.994 0.006 0.000
K29.6 Other gastritis
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.987 0.013 0.000
E10-E14 Diabetes mellitus
0.982 0.018 0.000
K55-K64 Other diseases of intestines
0.982 0.018 0.000
E70-E90 Metabolic disorders
0.982 0.018 0.000
Chapter IX Diseases of the circulatory system
0.982 0.018 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.976 0.024 0.000
K31.7 Polyp of stomach and duodenum
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
K70-K77 Diseases of liver
0.972 0.028 0.000
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
E11 Non-insulin-dependent diabetes mellitus
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.964 0.036 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.960 0.040 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.956 0.044 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.955 0.045 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.943 0.057 0.000
T81 Complications of procedures, not elsewhere classified
0.941 0.059 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.941 0.059 0.000
E78.0 Pure hypercholesterolaemia
0.937 0.063 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.936 0.064 0.000
K56.6 Other and unspecified intestinal obstruction
0.936 0.064 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.935 0.065 0.000
N10-N16 Renal tubulo-interstitial diseases
0.934 0.066 0.000
E11.9 Without complications
0.933 0.067 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.932 0.068 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.931 0.069 0.000
I20-I25 Ischaemic heart diseases
0.918 0.082 0.000
K29.8 Duodenitis
0.915 0.085 0.000
M05-M14 Inflammatory polyarthropathies
0.913 0.087 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.913 0.087 0.000
K76 Other diseases of liver
0.908 0.092 0.000
K26 Duodenal ulcer
0.907 0.093 0.000
Chapter II Neoplasms
0.895 0.105 0.000
I73 Other peripheral vascular diseases
0.893 0.107 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.888 0.112 0.000
G40-G47 Episodic and paroxysmal disorders
0.887 0.113 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.884 0.116 0.000
K31.8 Other specified diseases of stomach and duodenum
0.884 0.116 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.884 0.116 0.000
K90-K93 Other diseases of the digestive system
0.880 0.120 0.000
G90-G99 Other disorders of the nervous system
0.874 0.126 0.000
N13 Obstructive and reflux uropathy
0.874 0.126 0.000
K27 Peptic ulcer, site unspecified
0.873 0.127 0.000
I73.9 Peripheral vascular disease, unspecified
0.870 0.130 0.000
E11.3 With ophthalmic complications
0.869 0.131 0.000
K60 Fissure and fistula of anal and rectal regions
0.865 0.135 0.000
K58 Irritable bowel syndrome
0.863 0.137 0.000
M06 Other rheumatoid arthritis
0.863 0.137 0.000
I21 Acute myocardial infarction
0.861 0.139 0.000
A30-A49 Other bacterial diseases
0.859 0.140 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.857 0.143 0.000
Y83.8 Other surgical procedures
0.857 0.143 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.854 0.146 0.000
B95-B98 Bacterial, viral and other infectious agents
0.853 0.147 0.000
N20-N23 Urolithiasis
0.853 0.147 0.000
D69 Purpura and other haemorrhagic conditions
0.853 0.147 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.852 0.148 0.000
L82 Seborrhoeic keratosis
0.851 0.149 0.000
T79-T79 Certain early complications of trauma
0.849 0.151 0.000
Y83.6 Removal of other organ (partial) (total)
0.849 0.151 0.000
K56.7 Ileus, unspecified
0.841 0.159 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.839 0.161 0.000
K70 Alcoholic liver disease
0.839 0.161 0.000
I05-I09 Chronic rheumatic heart diseases
0.838 0.162 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.838 0.162 0.000
W20-W49 Exposure to inanimate mechanical forces
0.837 0.163 0.000
Y43 Primarily systemic agents
0.836 0.164 0.000
S90-S99 Injuries to the ankle and foot
0.833 0.167 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.832 0.168 0.000
I74 Arterial embolism and thrombosis
0.830 0.170 0.000
E14 Unspecified diabetes mellitus
0.829 0.171 0.000
S60-S69 Injuries to the wrist and hand
0.828 0.172 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.826 0.174 0.000
L85 Other epidermal thickening
0.819 0.181 0.000
M06.9 Rheumatoid arthritis, unspecified
0.815 0.185 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.815 0.185 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.814 0.186 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.811 0.189 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.808 0.192 0.000
N00-N08 Glomerular diseases
0.806 0.193 0.000
I25 Chronic ischaemic heart disease
0.806 0.194 0.000
D69.6 Thrombocytopenia, unspecified
0.803 0.197 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.802 0.198 0.000
E50-E64 Other nutritional deficiencies
0.802 0.198 0.000
G20-G26 Extrapyramidal and movement disorders
0.801 0.199 0.000
K55 Vascular disorders of intestine
0.798 0.202 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.797 0.203 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.796 0.204 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.795 0.205 0.000
N83.2 Other and unspecified ovarian cysts
0.794 0.206 0.000
B35-B49 Mycoses
0.793 0.207 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.793 0.207 0.000
I95 Hypotension
0.793 0.207 0.000
K29.1 Other acute gastritis
0.792 0.208 0.000
M86-M90 Other osteopathies
0.788 0.212 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.786 0.213 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.786 0.214 0.000
E86 Volume depletion
0.785 0.215 0.000
I70 Atherosclerosis
0.782 0.218 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.782 0.218 0.000
E78.5 Hyperlipidaemia, unspecified
0.781 0.219 0.000
K92 Other diseases of digestive system
0.780 0.220 0.000
N60-N64 Disorders of breast
0.777 0.223 0.000
S20-S29 Injuries to the thorax
0.776 0.224 0.000
Y83.3 Surgical operation with formation of external stoma
0.772 0.228 0.000
Y83.9 Surgical procedure, unspecified
0.772 0.228 0.000
K50-K52 Noninfective enteritis and colitis
0.771 0.229 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.769 0.231 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.768 0.232 0.000
Y52 Agents primarily affecting the cardiovascular system
0.768 0.232 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.768 0.232 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.768 0.232 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.767 0.233 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.766 0.234 0.000
Y43.3 Other antineoplastic drugs
0.765 0.235 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
W00-W19 Falls
0.764 0.236 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.764 0.236 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.761 0.238 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.761 0.238 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.759 0.241 0.000
K74 Fibrosis and cirrhosis of liver
0.758 0.242 0.000
K56.2 Volvulus
0.757 0.243 0.000
N17-N19 Renal failure
0.757 0.243 0.000
M05 Seropositive rheumatoid arthritis
0.756 0.244 0.000
K60.2 Anal fissure, unspecified
0.756 0.244 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.755 0.245 0.000
M70-M79 Other soft tissue disorders
0.755 0.245 0.000
Chapter XXII Codes for special purposes
0.754 0.246 0.000
Y83.4 Other reconstructive surgery
0.754 0.246 0.000
C51-C58 Malignant neoplasms of female genital organs
0.754 0.246 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.754 0.246 0.000
C64-C68 Malignant neoplasms of urinary tract
0.754 0.246 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
K76.6 Portal hypertension
0.751 0.249 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.751 0.249 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.747 0.253 0.000
E16 Other disorders of pancreatic internal secretion
0.747 0.253 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.746 0.254 0.000
I72 Other aneurysm
0.746 0.254 0.000
Y40 Systemic antibiotics
0.745 0.255 0.000
K56.4 Other impaction of intestine
0.745 0.255 0.000
I77 Other disorders of arteries and arterioles
0.745 0.255 0.000
E11.4 With neurological complications
0.744 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.743 0.257 0.000
K35-K38 Diseases of appendix
0.742 0.258 0.000
K29.4 Chronic atrophic gastritis
0.742 0.258 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.742 0.258 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.741 0.259 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.740 0.260 0.000
N87 Dysplasia of cervix uteri
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
K75 Other inflammatory liver diseases
0.739 0.261 0.000
A00-A09 Intestinal infectious diseases
0.738 0.262 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.738 0.262 0.000
E89.0 Postprocedural hypothyroidism
0.737 0.263 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.737 0.263 0.000
E20-E35 Disorders of other endocrine glands
0.734 0.265 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.734 0.266 0.000
G43 Migraine
0.734 0.266 0.000
K29.0 Acute haemorrhagic gastritis
0.731 0.268 0.000
T42.4 Benzodiazepines
0.731 0.269 0.000
K26.4 Chronic or unspecified with haemorrhage
0.730 0.270 0.000
N25-N29 Other disorders of kidney and ureter
0.730 0.270 0.000
I95.9 Hypotension, unspecified
0.729 0.271 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.729 0.271 0.000
M50-M54 Other dorsopathies
0.728 0.272 0.000
N23 Unspecified renal colic
0.728 0.272 0.000
N93 Other abnormal uterine and vaginal bleeding
0.728 0.272 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.727 0.273 0.000
K65-K67 Diseases of peritoneum
0.727 0.273 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.726 0.274 0.000
M13 Other arthritis
0.725 0.275 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.723 0.277 0.000
D50-D53 Nutritional anaemias
0.721 0.279 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
R11 Nausea and vomiting
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I25.2 Old myocardial infarction
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
K25 Gastric ulcer
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
Y00-Y09 Assault
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X60-X84 Intentional self-harm
0.714 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.285 0.000
X50-X57 Overexertion, travel and privation
0.714 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
S00-S09 Injuries to the head
0.714 0.286 0.000
K29.9 Gastroduodenitis, unspecified
0.713 0.287 0.000
K29.3 Chronic superficial gastritis
0.713 0.287 0.000
K29.2 Alcoholic gastritis
0.713 0.287 0.000
K31.6 Fistula of stomach and duodenum
0.713 0.287 0.000
K31.5 Obstruction of duodenum
0.713 0.287 0.000
K31.4 Gastric diverticulum
0.713 0.287 0.000
K31.3 Pylorospasm, not elsewhere classified
0.713 0.287 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.713 0.287 0.000
K31.0 Acute dilatation of stomach
0.713 0.287 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.712 0.288 0.000
Chapter VII Diseases of the eye and adnexa
0.712 0.288 0.000
E88 Other metabolic disorders
0.710 0.289 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.710 0.290 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.710 0.290 0.000
W29 Contact with other powered hand tools and household machinery
0.710 0.290 0.000
K60.3 Anal fistula
0.709 0.291 0.000
E14.3 With ophthalmic complications
0.709 0.291 0.000
A46 Erysipelas
0.709 0.291 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.708 0.292 0.000
G30-G32 Other degenerative diseases of the nervous system
0.707 0.292 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.706 0.294 0.000
E13 Other specified diabetes mellitus
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.296 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.704 0.296 0.000
E85 Amyloidosis
0.704 0.296 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.704 0.296 0.000
E79 Disorders of purine and pyrimidine metabolism
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
E73 Lactose intolerance
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.703 0.296 0.000
D00-D09 In situ neoplasms
0.703 0.297 0.000
M91-M94 Chondropathies
0.703 0.297 0.000
I08 Multiple valve diseases
0.703 0.297 0.000
L85.8 Other specified epidermal thickening
0.701 0.298 0.000
N13.3 Other and unspecified hydronephrosis
0.701 0.299 0.000
L89 Decubitus ulcer
0.701 0.299 0.000
K56.3 Gallstone ileus
0.700 0.300 0.000
K56.1 Intussusception
0.700 0.300 0.000
K56.0 Paralytic ileus
0.700 0.300 0.000
M40-M43 Deforming dorsopathies
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
I21.9 Acute myocardial infarction, unspecified
0.698 0.302 0.000
A49 Bacterial infection of unspecified site
0.698 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.697 0.302 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.697 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.697 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.697 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.697 0.302 0.000
K51 Ulcerative colitis
0.697 0.303 0.000
K77 Liver disorders in diseases classified elsewhere
0.697 0.303 0.000
K73 Chronic hepatitis, not elsewhere classified
0.697 0.303 0.000
K72 Hepatic failure, not elsewhere classified
0.697 0.303 0.000
K71 Toxic liver disease
0.697 0.303 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.695 0.305 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
B99-B99 Other infectious diseases
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.695 0.305 0.000
B15-B19 Viral hepatitis
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A80-A89 Viral infections of the central nervous system
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
I99 Other and unspecified disorders of circulatory system
0.695 0.305 0.000
E11.8 With unspecified complications
0.694 0.306 0.000
E11.7 With multiple complications
0.694 0.306 0.000
E11.6 With other specified complications
0.694 0.306 0.000
E11.5 With peripheral circulatory complications
0.694 0.306 0.000
E11.2 With renal complications
0.694 0.306 0.000
E11.1 With ketoacidosis
0.694 0.306 0.000
E11.0 With coma
0.694 0.306 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.693 0.307 0.000
K70.9 Alcoholic liver disease, unspecified
0.693 0.307 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.307 0.000
G93 Other disorders of brain
0.692 0.308 0.000
G70-G73 Diseases of myoneural junction and muscle
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
B35 Dermatophytosis
0.691 0.309 0.000
N03 Chronic nephritic syndrome
0.689 0.311 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.688 0.311 0.000
E78.8 Other disorders of lipoprotein metabolism
0.688 0.311 0.000
E78.6 Lipoprotein deficiency
0.688 0.311 0.000
E78.4 Other hyperlipidaemia
0.688 0.311 0.000
E78.3 Hyperchylomicronaemia
0.688 0.311 0.000
E78.2 Mixed hyperlipidaemia
0.688 0.311 0.000
E78.1 Pure hyperglyceridaemia
0.688 0.311 0.000
C15-C26 Malignant neoplasms of digestive organs
0.688 0.312 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.688 0.312 0.000
G95 Other diseases of spinal cord
0.687 0.313 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.687 0.313 0.000
L85.9 Epidermal thickening, unspecified
0.686 0.314 0.000
N87.1 Moderate cervical dysplasia
0.686 0.314 0.000
K70.1 Alcoholic hepatitis
0.686 0.314 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.685 0.315 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.685 0.315 0.000
G91 Hydrocephalus
0.684 0.316 0.000
L50-L54 Urticaria and erythema
0.684 0.316 0.000
M06.0 Seronegative rheumatoid arthritis
0.683 0.317 0.000
K61 Abscess of anal and rectal regions
0.682 0.318 0.000
C56 Malignant neoplasm of ovary
0.681 0.319 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.680 0.320 0.000
S92 Fracture of foot, except ankle
0.680 0.320 0.000
S80-S89 Injuries to the knee and lower leg
0.679 0.321 0.000
L84 Corns and callosities
0.678 0.322 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.678 0.322 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.678 0.322 0.000
M60-M63 Disorders of muscles
0.676 0.324 0.000
M00-M03 Infectious arthropathies
0.676 0.324 0.000
Chapter VIII Diseases of the ear and mastoid process
0.675 0.325 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.675 0.325 0.000
T81.9 Unspecified complication of procedure
0.675 0.325 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.675 0.325 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.675 0.325 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.675 0.325 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.675 0.325 0.000
Y83.5 Amputation of limb(s)
0.675 0.325 0.000
Y83.0 Surgical operation with transplant of whole organ
0.675 0.325 0.000
N13.8 Other obstructive and reflux uropathy
0.675 0.325 0.000
N40-N51 Diseases of male genital organs
0.674 0.326 0.000
L91 Hypertrophic disorders of skin
0.674 0.326 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.672 0.328 0.000
D80-D89 Certain disorders involving the immune mechanism
0.672 0.328 0.000
E16.2 Hypoglycaemia, unspecified
0.671 0.329 0.000
L10-L14 Bullous disorders
0.671 0.329 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.671 0.329 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y57 Other and unspecified drugs and medicaments
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.670 0.330 0.000
N15 Other renal tubulo-interstitial diseases
0.670 0.330 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.670 0.330 0.000
N11 Chronic tubulo-interstitial nephritis
0.670 0.330 0.000
N10 Acute tubulo-interstitial nephritis
0.670 0.330 0.000
N21 Calculus of lower urinary tract
0.669 0.331 0.000
A41 Other septicaemia
0.669 0.331 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.668 0.331 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.668 0.331 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.331 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.668 0.331 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.668 0.331 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.668 0.331 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.668 0.331 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.668 0.331 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.668 0.331 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.668 0.331 0.000
T36 Poisoning by systemic antibiotics
0.668 0.331 0.000
M10 Gout
0.668 0.332 0.000
M89 Other disorders of bone
0.668 0.332 0.000
D55-D59 Haemolytic anaemias
0.668 0.332 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.666 0.334 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.666 0.334 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.665 0.335 0.000
K40-K46 Hernia
0.664 0.336 0.000
R50-R69 General symptoms and signs
0.664 0.336 0.000
B02 Zoster [herpes zoster]
0.663 0.337 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.663 0.337 0.000
I22 Subsequent myocardial infarction
0.663 0.337 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.659 0.340 0.000
E65-E68 Obesity and other hyperalimentation
0.659 0.340 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.659 0.341 0.000
I07 Rheumatic tricuspid valve diseases
0.658 0.341 0.000
I23 Certain current complications following acute myocardial infarction
0.658 0.341 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.658 0.342 0.000
E55 Vitamin D deficiency
0.658 0.342 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.658 0.342 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.656 0.344 0.000
G20 Parkinson's disease
0.656 0.344 0.000
M65-M68 Disorders of synovium and tendon
0.656 0.344 0.000
K55.2 Angiodysplasia of colon
0.655 0.345 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.655 0.345 0.000
M14 Arthropathies in other diseases classified elsewhere
0.655 0.345 0.000
M12 Other specific arthropathies
0.655 0.345 0.000
M11 Other crystal arthropathies
0.655 0.345 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.655 0.345 0.000
M08 Juvenile arthritis
0.655 0.345 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.654 0.346 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.654 0.346 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.654 0.346 0.000
L94 Other localised connective tissue disorders
0.654 0.346 0.000
L93 Lupus erythematosus
0.654 0.346 0.000
L87 Transepidermal elimination disorders
0.654 0.346 0.000
L88 Pyoderma gangrenosum
0.654 0.346 0.000
L86 Keratoderma in diseases classified elsewhere
0.654 0.346 0.000
L83 Acanthosis nigricans
0.654 0.346 0.000
L80 Vitiligo
0.654 0.346 0.000
M72 Fibroblastic disorders
0.653 0.347 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.651 0.349 0.000
K76.7 Hepatorenal syndrome
0.651 0.349 0.000
K76.5 Hepatic veno-occlusive disease
0.651 0.349 0.000
K76.4 Peliosis hepatis
0.651 0.349 0.000
K76.3 Infarction of liver
0.651 0.349 0.000
K76.2 Central haemorrhagic necrosis of liver
0.651 0.349 0.000
K76.1 Chronic passive congestion of liver
0.651 0.349 0.000
K26.7 Chronic without haemorrhage or perforation
0.651 0.349 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.651 0.349 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.650 0.349 0.000
K26.5 Chronic or unspecified with perforation
0.650 0.349 0.000
K26.3 Acute without haemorrhage or perforation
0.650 0.349 0.000
K26.2 Acute with both haemorrhage and perforation
0.650 0.349 0.000
K26.1 Acute with perforation
0.650 0.349 0.000
K26.0 Acute with haemorrhage
0.650 0.349 0.000
M80-M85 Disorders of bone density and structure
0.650 0.350 0.000
S91 Open wound of ankle and foot
0.649 0.351 0.000
L90 Atrophic disorders of skin
0.648 0.352 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.648 0.352 0.000
S72 Fracture of femur
0.647 0.352 0.000
M07 Psoriatic and enteropathic arthropathies
0.647 0.353 0.000
C79 Secondary malignant neoplasm of other sites
0.647 0.353 0.000
S50-S59 Injuries to the elbow and forearm
0.643 0.357 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.643 0.357 0.000
G44 Other headache syndromes
0.642 0.358 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.641 0.359 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.641 0.359 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.641 0.359 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.641 0.359 0.000
I73.8 Other specified peripheral vascular diseases
0.640 0.360 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.640 0.360 0.000
S60 Superficial injury of wrist and hand
0.640 0.360 0.000
T43.2 Other and unspecified antidepressants
0.639 0.361 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.637 0.363 0.000
Y95 Nosocomial condition
0.636 0.364 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.636 0.364 0.000
G41 Status epilepticus
0.636 0.364 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.635 0.365 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.634 0.366 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.634 0.366 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.634 0.366 0.000
D67 Hereditary factor IX deficiency
0.634 0.366 0.000
D66 Hereditary factor VIII deficiency
0.634 0.366 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.634 0.366 0.000
C50-C50 Malignant neoplasm of breast
0.634 0.366 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.633 0.367 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.633 0.367 0.000
G40 Epilepsy
0.632 0.368 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.632 0.368 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.631 0.369 0.000
D60-D64 Aplastic and other anaemias
0.631 0.369 0.000
C67 Malignant neoplasm of bladder
0.630 0.369 0.000
M45-M49 Spondylopathies
0.627 0.373 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.627 0.373 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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