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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73224126
log Bayes Factor = 18.1836
Chromosome 4   position 13,056,615  (GRCh37) Explore rs73224126 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E66 Obesity
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E65-E68 Obesity and other hyperalimentation
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
E66.9 Obesity, unspecified
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Z51 Other medical care
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
E66.8 Other obesity
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.993 0.007 0.000
Z51.5 Palliative care
0.992 0.008 0.000
Z51.0 Radiotherapy session
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.988 0.012 0.000
J43 Emphysema
0.983 0.017 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.979 0.021 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.976 0.024 0.000
J09-J18 Influenza and pneumonia
0.976 0.024 0.000
J43.9 Emphysema, unspecified
0.970 0.030 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.969 0.031 0.000
Z51.1 Chemotherapy session for neoplasm
0.967 0.033 0.000
C50-C50 Malignant neoplasm of breast
0.966 0.034 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.965 0.035 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.963 0.037 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.962 0.038 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.959 0.041 0.000
C78.2 Secondary malignant neoplasm of pleura
0.958 0.042 0.000
C34 Malignant neoplasm of bronchus and lung
0.955 0.045 0.000
J44 Other chronic obstructive pulmonary disease
0.955 0.045 0.000
J18 Pneumonia, organism unspecified
0.954 0.046 0.000
E20-E35 Disorders of other endocrine glands
0.945 0.055 0.000
C50 Malignant neoplasm of breast
0.942 0.058 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.942 0.058 0.000
O20 Haemorrhage in early pregnancy
0.937 0.063 0.000
C15-C26 Malignant neoplasms of digestive organs
0.935 0.065 0.000
M70-M79 Other soft tissue disorders
0.934 0.066 0.000
J40 Bronchitis, not specified as acute or chronic
0.933 0.067 0.000
Y95 Nosocomial condition
0.933 0.067 0.000
J18.1 Lobar pneumonia, unspecified
0.929 0.071 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.927 0.073 0.000
M75 Shoulder lesions
0.923 0.077 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.922 0.078 0.000
C79 Secondary malignant neoplasm of other sites
0.917 0.083 0.000
O36 Maternal care for other known or suspected foetal problems
0.916 0.084 0.000
D68 Other coagulation defects
0.910 0.090 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.908 0.092 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.906 0.094 0.000
Z92 Personal history of medical treatment
0.905 0.095 0.000
O20.0 Threatened abortion
0.899 0.101 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.892 0.108 0.000
C77.1 Intrathoracic lymph nodes
0.886 0.114 0.000
C50.9 Breast, unspecified
0.885 0.115 0.000
J20-J22 Other acute lower respiratory infections
0.883 0.117 0.000
O80-O84 Delivery
0.882 0.118 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.881 0.119 0.000
C34.9 Bronchus or lung, unspecified
0.880 0.120 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.879 0.121 0.000
C77.3 Axillary and upper limb lymph nodes
0.879 0.121 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.873 0.127 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.870 0.130 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
M75.5 Bursitis of shoulder
0.863 0.137 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.862 0.138 0.000
S50-S59 Injuries to the elbow and forearm
0.857 0.143 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.856 0.144 0.000
Z52 Donors of organs and tissues
0.856 0.144 0.000
Z51.8 Other specified medical care
0.854 0.146 0.000
Z92.3 Personal history of irradiation
0.853 0.147 0.000
J47 Bronchiectasis
0.849 0.151 0.000
C34.1 Upper lobe, bronchus or lung
0.847 0.153 0.000
Chapter XXII Codes for special purposes
0.843 0.157 0.000
J30-J39 Other diseases of upper respiratory tract
0.838 0.162 0.000
D69 Purpura and other haemorrhagic conditions
0.837 0.163 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.836 0.164 0.000
J42 Unspecified chronic bronchitis
0.831 0.169 0.000
D50-D53 Nutritional anaemias
0.830 0.170 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.830 0.170 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.825 0.175 0.000
J90-J94 Other diseases of pleura
0.824 0.176 0.000
W20-W49 Exposure to inanimate mechanical forces
0.824 0.176 0.000
V10-V19 Pedal cyclist injured in transport accident
0.822 0.178 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.821 0.179 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.818 0.182 0.000
O80 Single spontaneous delivery
0.815 0.185 0.000
Chapter VIII Diseases of the ear and mastoid process
0.815 0.185 0.000
Z41 Procedures for purposes other than remedying health state
0.814 0.186 0.000
Z80 Family history of malignant neoplasm
0.813 0.187 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.812 0.188 0.000
M75.1 Rotator cuff syndrome
0.808 0.192 0.000
J18.0 Bronchopneumonia, unspecified
0.807 0.193 0.000
E22 Hyperfunction of pituitary gland
0.805 0.195 0.000
C34.3 Lower lobe, bronchus or lung
0.804 0.196 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.801 0.199 0.000
M75.0 Adhesive capsulitis of shoulder
0.800 0.200 0.000
S70-S79 Injuries to the hip and thigh
0.799 0.201 0.000
C51-C58 Malignant neoplasms of female genital organs
0.798 0.202 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.798 0.202 0.000
M86-M90 Other osteopathies
0.797 0.203 0.000
C32 Malignant neoplasm of larynx
0.796 0.204 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.795 0.205 0.000
S52 Fracture of forearm
0.794 0.206 0.000
C71 Malignant neoplasm of brain
0.793 0.207 0.000
M76 Enthesopathies of lower limb, excluding foot
0.791 0.209 0.000
C50.8 Overlapping lesion of breast
0.790 0.210 0.000
E23 Hypofunction and other disorders of pituitary gland
0.790 0.210 0.000
O36.8 Maternal care for other specified foetal problems
0.789 0.211 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.788 0.212 0.000
J22 Unspecified acute lower respiratory infection
0.787 0.213 0.000
M75.4 Impingement syndrome of shoulder
0.786 0.214 0.000
O80.0 Spontaneous vertex delivery
0.784 0.216 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.783 0.217 0.000
D80-D89 Certain disorders involving the immune mechanism
0.782 0.218 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.778 0.222 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.778 0.222 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.778 0.222 0.000
O32.1 Maternal care for breech presentation
0.777 0.223 0.000
O00-O08 Pregnancy with abortive outcome
0.776 0.224 0.000
J45 Asthma
0.776 0.224 0.000
D68.2 Hereditary deficiency of other clotting factors
0.774 0.226 0.000
Z85 Personal history of malignant neoplasm
0.772 0.228 0.000
D68.8 Other specified coagulation defects
0.772 0.228 0.000
O85-O92 Complications predominantly related to the puerperium
0.771 0.229 0.000
E70-E90 Metabolic disorders
0.768 0.232 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.766 0.234 0.000
O20.8 Other haemorrhage in early pregnancy
0.765 0.235 0.000
O36.9 Maternal care for foetal problem, unspecified
0.763 0.237 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.762 0.238 0.000
C60-C63 Malignant neoplasms of male genital organs
0.761 0.239 0.000
D66 Hereditary factor VIII deficiency
0.759 0.241 0.000
W50-W64 Exposure to animate mechanical forces
0.759 0.241 0.000
Z52.4 Kidney donor
0.758 0.242 0.000
J46 Status asthmaticus
0.757 0.243 0.000
W00-W19 Falls
0.757 0.243 0.000
O44 Placenta praevia
0.756 0.244 0.000
Z51.9 Medical care, unspecified
0.755 0.245 0.000
S10-S19 Injuries to the neck
0.753 0.247 0.000
C45 Mesothelioma
0.752 0.248 0.000
D75 Other diseases of blood and blood-forming organs
0.751 0.249 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.748 0.252 0.000
C16 Malignant neoplasm of stomach
0.748 0.252 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.748 0.252 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
J30 Vasomotor and allergic rhinitis
0.745 0.255 0.000
C50.5 Lower-outer quadrant of breast
0.745 0.255 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.745 0.255 0.000
Z45 Adjustment and management of implanted device
0.745 0.255 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.744 0.256 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.742 0.258 0.000
C50.3 Lower-inner quadrant of breast
0.741 0.259 0.000
E27 Other disorders of adrenal gland
0.740 0.259 0.000
O23 Infections of genito-urinary tract in pregnancy
0.740 0.260 0.000
E50-E64 Other nutritional deficiencies
0.739 0.261 0.000
M45-M49 Spondylopathies
0.739 0.261 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.738 0.262 0.000
O36.5 Maternal care for poor foetal growth
0.738 0.262 0.000
O21 Excessive vomiting in pregnancy
0.738 0.262 0.000
E40-E46 Malnutrition
0.737 0.263 0.000
J60-J70 Lung diseases due to external agents
0.737 0.263 0.000
V20-V29 Motorcycle rider injured in transport accident
0.736 0.264 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.735 0.265 0.000
S20-S29 Injuries to the thorax
0.734 0.266 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.733 0.267 0.000
Z43 Attention to artificial openings
0.733 0.267 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.732 0.268 0.000
D68.9 Coagulation defect, unspecified
0.732 0.268 0.000
M91-M94 Chondropathies
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.731 0.269 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.731 0.269 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.727 0.273 0.000
C77.8 Lymph nodes of multiple regions
0.726 0.273 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.726 0.274 0.000
C50.0 Nipple and areola
0.726 0.274 0.000
J11 Influenza, virus not identified
0.725 0.275 0.000
O24 Diabetes mellitus in pregnancy
0.724 0.275 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.724 0.276 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.723 0.277 0.000
Q50-Q56 Congenital malformations of genital organs
0.723 0.277 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.721 0.279 0.000
Z90.1 Acquired absence of breast(s)
0.721 0.279 0.000
C77.5 Intrapelvic lymph nodes
0.720 0.280 0.000
D68.0 Von Willebrand's disease
0.720 0.280 0.000
Y43 Primarily systemic agents
0.719 0.281 0.000
J10 Influenza due to identified influenza virus
0.718 0.282 0.000
C79.6 Secondary malignant neoplasm of ovary
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.717 0.283 0.000
E66.1 Drug-induced obesity
0.717 0.283 0.000
E66.0 Obesity due to excess calories
0.717 0.283 0.000
E67 Other hyperalimentation
0.717 0.283 0.000
E68 Sequelae of hyperalimentation
0.717 0.283 0.000
E65 Localised adiposity
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
D69.6 Thrombocytopenia, unspecified
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
O43 Placental disorders
0.713 0.287 0.000
C50.1 Central portion of breast
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.712 0.288 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.712 0.288 0.000
J84 Other interstitial pulmonary diseases
0.711 0.289 0.000
E22.0 Acromegaly and pituitary gigantism
0.710 0.290 0.000
O32.2 Maternal care for transverse and oblique lie
0.710 0.290 0.000
E29 Testicular dysfunction
0.710 0.290 0.000
C80 Malignant neoplasm without specification of site
0.710 0.290 0.000
W22 Striking against or struck by other objects
0.710 0.290 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.709 0.291 0.000
D55-D59 Haemolytic anaemias
0.708 0.291 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.708 0.292 0.000
C77.2 Intra-abdominal lymph nodes
0.706 0.294 0.000
E10-E14 Diabetes mellitus
0.706 0.294 0.000
Z92.8 Personal history of other medical treatment
0.705 0.294 0.000
C79.2 Secondary malignant neoplasm of skin
0.705 0.295 0.000
J43.8 Other emphysema
0.704 0.295 0.000
J43.2 Centrilobular emphysema
0.704 0.295 0.000
J43.1 Panlobular emphysema
0.704 0.295 0.000
J43.0 MacLeod's syndrome
0.704 0.295 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.702 0.298 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.702 0.298 0.000
C31 Malignant neoplasm of accessory sinuses
0.702 0.298 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.702 0.298 0.000
C37 Malignant neoplasm of thymus
0.702 0.298 0.000
C33 Malignant neoplasm of trachea
0.702 0.298 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.298 0.000
E87.2 Acidosis
0.700 0.300 0.000
O45 Premature separation of placenta [abruptio placentae]
0.700 0.300 0.000
O33 Maternal care for known or suspected disproportion
0.700 0.300 0.000
O31 Complications specific to multiple gestation
0.700 0.300 0.000
J17 Pneumonia in diseases classified elsewhere
0.700 0.300 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.700 0.300 0.000
J12 Viral pneumonia, not elsewhere classified
0.700 0.300 0.000
J14 Pneumonia due to Haemophilus influenzae
0.700 0.300 0.000
J09 Influenza due to certain identified influenza virus
0.700 0.300 0.000
J39 Other diseases of upper respiratory tract
0.699 0.301 0.000
S52.0 Fracture of upper end of ulna
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.698 0.302 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.697 0.303 0.000
O40 Polyhydramnios
0.696 0.303 0.000
C20 Malignant neoplasm of rectum
0.695 0.305 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.695 0.305 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.695 0.305 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.695 0.305 0.000
O29 Complications of anaesthesia during pregnancy
0.692 0.308 0.000
O28 Abnormal findings on antenatal screening of mother
0.692 0.308 0.000
O22 Venous complications in pregnancy
0.692 0.308 0.000
O25 Malnutrition in pregnancy
0.692 0.308 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.691 0.309 0.000
C21 Malignant neoplasm of anus and anal canal
0.691 0.309 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
O30 Multiple gestation
0.691 0.309 0.000
D67 Hereditary factor IX deficiency
0.690 0.310 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.690 0.310 0.000
D50 Iron deficiency anaemia
0.690 0.310 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
C71.9 Brain, unspecified
0.690 0.310 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.689 0.311 0.000
M76.6 Achilles tendinitis
0.688 0.311 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.688 0.312 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.688 0.312 0.000
Y98 Lifestyle-related condition
0.688 0.312 0.000
Y97 Environmental-pollution-related condition
0.688 0.312 0.000
Y96 Work-related condition
0.688 0.312 0.000
Z54 Convalescence
0.687 0.313 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
S79 Other and unspecified injuries of hip and thigh
0.687 0.313 0.000
C15 Malignant neoplasm of oesophagus
0.686 0.314 0.000
J93 Pneumothorax
0.686 0.314 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.686 0.314 0.000
C34.8 Overlapping lesion of bronchus and lung
0.685 0.315 0.000
C34.2 Middle lobe, bronchus or lung
0.685 0.315 0.000
C34.0 Main bronchus
0.685 0.315 0.000
H90-H95 Other disorders of ear
0.684 0.316 0.000
J18.8 Other pneumonia, organism unspecified
0.684 0.316 0.000
J18.2 Hypostatic pneumonia, unspecified
0.684 0.316 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.682 0.318 0.000
X60-X84 Intentional self-harm
0.681 0.318 0.000
J35 Chronic diseases of tonsils and adenoids
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.678 0.322 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.678 0.322 0.000
E34 Other endocrine disorders
0.678 0.322 0.000
E32 Diseases of thymus
0.678 0.322 0.000
E31 Polyglandular dysfunction
0.678 0.322 0.000
E30 Disorders of puberty, not elsewhere classified
0.678 0.322 0.000
E26 Hyperaldosteronism
0.678 0.322 0.000
E25 Adrenogenital disorders
0.678 0.322 0.000
E24 Cushing's syndrome
0.678 0.322 0.000
E20 Hypoparathyroidism
0.678 0.322 0.000
C56 Malignant neoplasm of ovary
0.677 0.323 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.677 0.323 0.000
M71 Other bursopathies
0.676 0.324 0.000
D75.1 Secondary polycythaemia
0.676 0.324 0.000
C50.6 Axillary tail of breast
0.675 0.324 0.000
M60-M63 Disorders of muscles
0.675 0.325 0.000
M00-M03 Infectious arthropathies
0.675 0.325 0.000
S40-S49 Injuries to the shoulder and upper arm
0.674 0.326 0.000
Z48 Other surgical follow-up care
0.673 0.327 0.000
Z81 Family history of mental and behavioural disorders
0.673 0.327 0.000
D45 Polycythaemia vera
0.672 0.327 0.000
Z22 Carrier of infectious disease
0.672 0.328 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
C77.9 Lymph node, unspecified
0.671 0.329 0.000
S52.6 Fracture of lower end of both ulna and radius
0.670 0.330 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.670 0.330 0.000
C17 Malignant neoplasm of small intestine
0.670 0.330 0.000
C23 Malignant neoplasm of gallbladder
0.670 0.330 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.670 0.330 0.000
O46.9 Antepartum haemorrhage, unspecified
0.670 0.330 0.000
C50.2 Upper-inner quadrant of breast
0.670 0.330 0.000
Z49 Care involving dialysis
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
D10-D36 Benign neoplasms
0.669 0.331 0.000
J94 Other pleural conditions
0.669 0.331 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.669 0.331 0.000
H60-H62 Diseases of external ear
0.668 0.332 0.000
O41 Other disorders of amniotic fluid and membranes
0.668 0.332 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.668 0.332 0.000
J00-J06 Acute upper respiratory infections
0.668 0.332 0.000
M72 Fibroblastic disorders
0.667 0.332 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.666 0.334 0.000
S56 Injury of muscle and tendon at forearm level
0.666 0.334 0.000
J91 Pleural effusion in conditions classified elsewhere
0.666 0.334 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.666 0.334 0.000
Y52 Agents primarily affecting the cardiovascular system
0.665 0.335 0.000
O48 Prolonged pregnancy
0.665 0.335 0.000
J20 Acute bronchitis
0.665 0.335 0.000
T33-T35 Frostbite
0.665 0.335 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.665 0.335 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.665 0.335 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.665 0.335 0.000
E23.0 Hypopituitarism
0.664 0.336 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.664 0.336 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.662 0.338 0.000
M75.2 Bicipital tendinitis
0.662 0.338 0.000
Z90.0 Acquired absence of part of head and neck
0.662 0.338 0.000
C32.9 Larynx, unspecified
0.662 0.338 0.000
M75.8 Other shoulder lesions
0.661 0.338 0.000
M75.9 Shoulder lesion, unspecified
0.661 0.338 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.660 0.340 0.000
D53 Other nutritional anaemias
0.660 0.340 0.000
M70.2 Olecranon bursitis
0.660 0.340 0.000
J30.1 Allergic rhinitis due to pollen
0.660 0.340 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.659 0.340 0.000
Z80.6 Family history of leukaemia
0.659 0.341 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.659 0.341 0.000
Chapter VI Diseases of the nervous system
0.658 0.342 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.658 0.342 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.658 0.342 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.658 0.342 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.658 0.342 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.658 0.342 0.000
H80-H83 Diseases of inner ear
0.657 0.343 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.657 0.343 0.000
O36.4 Maternal care for intra-uterine death
0.657 0.343 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.657 0.343 0.000
O36.2 Maternal care for hydrops foetalis
0.657 0.343 0.000
O36.1 Maternal care for other isoimmunisation
0.657 0.343 0.000
C77.4 Inguinal and lower limb lymph nodes
0.655 0.345 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.655 0.345 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.655 0.345 0.000
M65-M68 Disorders of synovium and tendon
0.654 0.346 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.654 0.346 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.654 0.346 0.000
O81 Single delivery by forceps and vacuum extractor
0.653 0.347 0.000
D68.6 Other Thrombophilia
0.653 0.347 0.000
D68.5 Primary Thrombophilia
0.653 0.347 0.000
D68.4 Acquired coagulation factor deficiency
0.653 0.347 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.653 0.347 0.000
D68.1 Hereditary factor XI deficiency
0.653 0.347 0.000
D00-D09 In situ neoplasms
0.651 0.349 0.000
C07 Malignant neoplasm of parotid gland
0.650 0.350 0.000
Z84 Family history of other conditions
0.649 0.351 0.000
C78.7 Secondary malignant neoplasm of liver
0.649 0.351 0.000
Z92.9 Personal history of medical treatment, unspecified
0.649 0.351 0.000
Z92.5 Personal history of rehabilitation measures
0.649 0.351 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.648 0.352 0.000
D72 Other disorders of white blood cells
0.647 0.353 0.000
M89 Other disorders of bone
0.646 0.353 0.000
O60-O75 Complications of labour and delivery
0.646 0.354 0.000
S80-S89 Injuries to the knee and lower leg
0.646 0.354 0.000
J45.0 Predominantly allergic asthma
0.645 0.355 0.000
E87.6 Hypokalaemia
0.643 0.357 0.000
M45 Ankylosing spondylitis
0.643 0.357 0.000
S90-S99 Injuries to the ankle and foot
0.642 0.357 0.000
S52.2 Fracture of shaft of ulna
0.642 0.358 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.641 0.359 0.000
Y84.8 Other medical procedures
0.640 0.360 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.639 0.360 0.000
O32.8 Maternal care for other malpresentation of foetus
0.639 0.360 0.000
O32.6 Maternal care for compound presentation
0.639 0.360 0.000
O32.4 Maternal care for high head at term
0.639 0.360 0.000
O32.3 Maternal care for face, brow and chin presentation
0.639 0.360 0.000
O32.0 Maternal care for unstable lie
0.639 0.360 0.000
J37 Chronic laryngitis and laryngotracheitis
0.639 0.361 0.000
E73 Lactose intolerance
0.639 0.361 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.639 0.361 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.639 0.361 0.000
J18.9 Pneumonia, unspecified
0.638 0.362 0.000
E27.8 Other specified disorders of adrenal gland
0.638 0.362 0.000
W13 Fall from, out of or through building or structure
0.638 0.362 0.000
Z30 Contraceptive management
0.638 0.362 0.000
J81 Pulmonary oedema
0.637 0.363 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.636 0.364 0.000
C61 Malignant neoplasm of prostate
0.636 0.364 0.000
C71.2 Temporal lobe
0.634 0.366 0.000
J21 Acute bronchiolitis
0.633 0.367 0.000
O84 Multiple delivery
0.632 0.368 0.000
O83 Other assisted single delivery
0.632 0.368 0.000
Chapter V Mental and behavioural disorders
0.632 0.368 0.000
M87 Osteonecrosis
0.632 0.368 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.632 0.368 0.000
J32 Chronic sinusitis
0.631 0.369 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.631 0.369 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.630 0.370 0.000
C70 Malignant neoplasm of meninges
0.630 0.370 0.000
C69 Malignant neoplasm of eye and adnexa
0.630 0.370 0.000
S52.00 Fracture of upper end of ulna (closed)
0.630 0.370 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.630 0.370 0.000
S70 Superficial injury of hip and thigh
0.629 0.371 0.000
S60-S69 Injuries to the wrist and hand
0.629 0.371 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.628 0.372 0.000
W22.9 Unspecified place
0.628 0.372 0.000
S12 Fracture of neck
0.628 0.372 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.627 0.372 0.000
C45.7 Mesothelioma of other sites
0.627 0.373 0.000
Z93 Artificial opening status
0.627 0.373 0.000
D73 Diseases of spleen
0.627 0.373 0.000
Y59 Other and unspecified vaccines and biological substances
0.626 0.374 0.000
Y58 Bacterial vaccines
0.626 0.374 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.626 0.374 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.626 0.374 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.626 0.374 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.626 0.374 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.626 0.374 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.626 0.374 0.000
Y48 Anaesthetics and therapeutic gases
0.626 0.374 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.626 0.374 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.626 0.374 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.626 0.374 0.000
J36 Peritonsillar abscess
0.624 0.376 0.000
S51 Open wound of forearm
0.624 0.376 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.624 0.376 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.624 0.376 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.624 0.376 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.624 0.376 0.000
J15.1 Pneumonia due to Pseudomonas
0.623 0.377 0.000
C09 Malignant neoplasm of tonsil
0.623 0.377 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.622 0.378 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.622 0.378 0.000
C18 Malignant neoplasm of colon
0.622 0.378 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.621 0.379 0.000
C53 Malignant neoplasm of cervix uteri
0.621 0.379 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.620 0.379 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.620 0.379 0.000
Q35-Q37 Cleft lip and cleft palate
0.620 0.379 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.620 0.379 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.620 0.380 0.000
C71.3 Parietal lobe
0.620 0.380 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.619 0.381 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.618 0.382 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.618 0.382 0.000
C46 Kaposi's sarcoma
0.618 0.382 0.000
Z36 Antenatal screening
0.618 0.382 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.618 0.382 0.000
S71 Open wound of hip and thigh
0.618 0.382 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.617 0.382 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.617 0.383 0.000
E28 Ovarian dysfunction
0.617 0.383 0.000
C77.0 Lymph nodes of head, face and neck
0.616 0.384 0.000
T78 Adverse effects, not elsewhere classified
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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