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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73366442
log Bayes Factor = 12.0256
Chromosome 7   position 73,989,491  (GRCh37) Explore rs73366442 on Ensembl!
Variant rs73366442 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.991 0.009 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.989 0.011 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.987 0.013 0.000
I20 Angina pectoris
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.978 0.022 0.000
I60-I69 Cerebrovascular diseases
0.976 0.024 0.000
O60-O75 Complications of labour and delivery
0.976 0.024 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.974 0.026 0.000
I25.2 Old myocardial infarction
0.973 0.027 0.000
Chapter VI Diseases of the nervous system
0.972 0.028 0.000
Z95.0 Presence of cardiac pacemaker
0.969 0.031 0.000
I20.9 Angina pectoris, unspecified
0.959 0.041 0.000
Z37 Outcome of delivery
0.958 0.042 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.954 0.046 0.000
M70-M79 Other soft tissue disorders
0.953 0.047 0.000
I22 Subsequent myocardial infarction
0.942 0.058 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.941 0.059 0.000
Chapter X Diseases of the respiratory system
0.936 0.064 0.000
M75 Shoulder lesions
0.933 0.067 0.000
J09-J18 Influenza and pneumonia
0.927 0.073 0.000
Z37.0 Single live birth
0.925 0.075 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.921 0.079 0.000
G90-G99 Other disorders of the nervous system
0.920 0.080 0.000
Z97 Presence of other devices
0.918 0.082 0.000
J18 Pneumonia, organism unspecified
0.918 0.082 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.917 0.083 0.000
Z95.1 Presence of aortocoronary bypass graft
0.914 0.086 0.000
O47 False labour
0.914 0.086 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.910 0.090 0.000
O63 Long labour
0.909 0.091 0.000
M45-M49 Spondylopathies
0.906 0.094 0.000
J18.9 Pneumonia, unspecified
0.905 0.095 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.902 0.098 0.000
G93 Other disorders of brain
0.890 0.110 0.000
G20-G26 Extrapyramidal and movement disorders
0.883 0.117 0.000
M47 Spondylosis
0.876 0.124 0.000
I25.1 Atherosclerotic heart disease
0.876 0.124 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.871 0.128 0.000
I20.0 Unstable angina
0.871 0.129 0.000
I63 Cerebral infarction
0.868 0.132 0.000
Z93 Artificial opening status
0.867 0.133 0.000
Z37.2 Twins, both liveborn
0.866 0.134 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.865 0.135 0.000
I30-I52 Other forms of heart disease
0.865 0.135 0.000
I65.2 Occlusion and stenosis of carotid artery
0.863 0.137 0.000
I24 Other acute ischaemic heart diseases
0.862 0.138 0.000
M75.1 Rotator cuff syndrome
0.861 0.139 0.000
O80-O84 Delivery
0.859 0.141 0.000
M47.8 Other spondylosis
0.855 0.145 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.848 0.152 0.000
M47.82 Other spondylosis (Cervical region)
0.847 0.153 0.000
I05-I09 Chronic rheumatic heart diseases
0.847 0.153 0.000
H60-H62 Diseases of external ear
0.845 0.155 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.840 0.160 0.000
Z97.0 Presence of artificial eye
0.837 0.163 0.000
H65-H75 Diseases of middle ear and mastoid
0.836 0.164 0.000
I25.5 Ischaemic cardiomyopathy
0.834 0.166 0.000
O70 Perineal laceration during delivery
0.833 0.167 0.000
I71 Aortic aneurysm and dissection
0.830 0.170 0.000
Z95.2 Presence of prosthetic heart valve
0.829 0.171 0.000
O48 Prolonged pregnancy
0.829 0.171 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.827 0.173 0.000
G93.3 Postviral fatigue syndrome
0.825 0.175 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.823 0.177 0.000
O36 Maternal care for other known or suspected foetal problems
0.823 0.177 0.000
H90-H95 Other disorders of ear
0.821 0.179 0.000
O30 Multiple gestation
0.820 0.180 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.820 0.180 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.819 0.181 0.000
M80-M85 Disorders of bone density and structure
0.819 0.181 0.000
I61 Intracerebral haemorrhage
0.817 0.183 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.811 0.189 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.809 0.190 0.000
O44 Placenta praevia
0.809 0.191 0.000
Chapter I Certain infectious and parasitic diseases
0.808 0.192 0.000
G25 Other extrapyramidal and movement disorders
0.806 0.194 0.000
O63.0 Prolonged first stage (of labour)
0.804 0.196 0.000
O63.9 Long labour, unspecified
0.804 0.196 0.000
M86-M90 Other osteopathies
0.803 0.197 0.000
M75.2 Bicipital tendinitis
0.801 0.199 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
G30-G32 Other degenerative diseases of the nervous system
0.798 0.202 0.000
Z36 Antenatal screening
0.795 0.205 0.000
J18.1 Lobar pneumonia, unspecified
0.795 0.205 0.000
S70-S79 Injuries to the hip and thigh
0.794 0.206 0.000
H65 Nonsuppurative otitis media
0.794 0.206 0.000
I67 Other cerebrovascular diseases
0.792 0.208 0.000
I63.9 Cerebral infarction, unspecified
0.792 0.208 0.000
M75.5 Bursitis of shoulder
0.792 0.208 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.791 0.209 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.790 0.210 0.000
G93.9 Disorder of brain, unspecified
0.789 0.210 0.000
Z88.6 Personal history of allergy to analgesic agent
0.789 0.211 0.000
Chapter V Mental and behavioural disorders
0.789 0.211 0.000
Z95.4 Presence of other heart-valve replacement
0.789 0.211 0.000
I95 Hypotension
0.788 0.212 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.787 0.213 0.000
Z33 Pregnant state, incidental
0.785 0.215 0.000
Z83 Family history of other specific disorders
0.784 0.216 0.000
M75.4 Impingement syndrome of shoulder
0.784 0.216 0.000
H61 Other disorders of external ear
0.779 0.221 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.779 0.221 0.000
Z34 Supervision of normal pregnancy
0.776 0.224 0.000
Chapter XIV Diseases of the genitourinary system
0.776 0.224 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.774 0.226 0.000
N20-N23 Urolithiasis
0.773 0.227 0.000
O47.9 False labour, unspecified
0.773 0.227 0.000
N20 Calculus of kidney and ureter
0.769 0.231 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.767 0.233 0.000
I22.8 Subsequent myocardial infarction of other sites
0.763 0.236 0.000
Z93.2 Ileostomy status
0.759 0.241 0.000
O62 Abnormalities of forces of labour
0.758 0.242 0.000
M75.3 Calcific tendinitis of shoulder
0.757 0.243 0.000
I69 Sequelae of cerebrovascular disease
0.753 0.247 0.000
O80 Single spontaneous delivery
0.753 0.247 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.751 0.248 0.000
H65.3 Chronic mucoid otitis media
0.751 0.249 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.749 0.251 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.745 0.255 0.000
M60-M63 Disorders of muscles
0.743 0.257 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.742 0.257 0.000
O40 Polyhydramnios
0.742 0.258 0.000
Z81 Family history of mental and behavioural disorders
0.739 0.260 0.000
G40-G47 Episodic and paroxysmal disorders
0.739 0.261 0.000
H91 Other hearing loss
0.737 0.263 0.000
I46 Cardiac arrest
0.736 0.264 0.000
M77 Other enthesopathies
0.734 0.266 0.000
Z89 Acquired absence of limb
0.732 0.268 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.732 0.268 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.269 0.000
O36.8 Maternal care for other specified foetal problems
0.730 0.270 0.000
O41 Other disorders of amniotic fluid and membranes
0.730 0.270 0.000
O42 Premature rupture of membranes
0.728 0.272 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.727 0.273 0.000
N20.1 Calculus of ureter
0.726 0.274 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.726 0.274 0.000
J40-J47 Chronic lower respiratory diseases
0.725 0.275 0.000
H61.0 Perichondritis of external ear
0.724 0.276 0.000
S72 Fracture of femur
0.724 0.276 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.724 0.276 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.723 0.277 0.000
O70.0 First degree perineal laceration during delivery
0.720 0.280 0.000
I05 Rheumatic mitral valve diseases
0.718 0.282 0.000
I72 Other aneurysm
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Z31 Procreative management
0.716 0.283 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.716 0.284 0.000
N20.0 Calculus of kidney
0.716 0.284 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.716 0.284 0.000
M40-M43 Deforming dorsopathies
0.715 0.285 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.714 0.286 0.000
Chapter XX External causes of morbidity and mortality
0.713 0.287 0.000
I62 Other nontraumatic intracranial haemorrhage
0.713 0.287 0.000
I95.1 Orthostatic hypotension
0.713 0.287 0.000
S50-S59 Injuries to the elbow and forearm
0.712 0.288 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.712 0.288 0.000
O73 Retained placenta and membranes, without haemorrhage
0.710 0.290 0.000
Z84 Family history of other conditions
0.710 0.290 0.000
Z95.3 Presence of xenogenic heart valve
0.710 0.290 0.000
O45 Premature separation of placenta [abruptio placentae]
0.708 0.292 0.000
O43 Placental disorders
0.708 0.292 0.000
O33 Maternal care for known or suspected disproportion
0.708 0.292 0.000
O31 Complications specific to multiple gestation
0.708 0.292 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.707 0.293 0.000
I24.8 Other forms of acute ischaemic heart disease
0.705 0.295 0.000
Chapter XXII Codes for special purposes
0.704 0.295 0.000
I20.1 Angina pectoris with documented spasm
0.703 0.297 0.000
J60-J70 Lung diseases due to external agents
0.703 0.297 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.703 0.297 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.702 0.298 0.000
M91-M94 Chondropathies
0.701 0.299 0.000
M00-M03 Infectious arthropathies
0.701 0.299 0.000
O30.0 Twin pregnancy
0.700 0.300 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.700 0.300 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.700 0.300 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.700 0.300 0.000
O74 Complications of anaesthesia during labour and delivery
0.699 0.300 0.000
O71 Other obstetric trauma
0.699 0.300 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.699 0.300 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.699 0.300 0.000
O61 Failed induction of labour
0.699 0.300 0.000
O60 Preterm delivery
0.699 0.300 0.000
Z38 Liveborn infants according to place of birth
0.698 0.302 0.000
Z32 Pregnancy examination and test
0.698 0.302 0.000
Z39 Postpartum care and examination
0.698 0.302 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.698 0.302 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.697 0.303 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.697 0.303 0.000
I27 Other pulmonary heart diseases
0.696 0.304 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.696 0.304 0.000
O80.0 Spontaneous vertex delivery
0.696 0.304 0.000
I67.8 Other specified cerebrovascular diseases
0.695 0.305 0.000
G91 Hydrocephalus
0.695 0.305 0.000
S20-S29 Injuries to the thorax
0.695 0.305 0.000
Z83.3 Family history of diabetes mellitus
0.694 0.306 0.000
J95-J99 Other diseases of the respiratory system
0.693 0.307 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.691 0.309 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.691 0.309 0.000
I74 Arterial embolism and thrombosis
0.688 0.312 0.000
Z75 Problems related to medical facilities and other health care
0.687 0.313 0.000
Z37.9 Outcome of delivery unspecified
0.687 0.313 0.000
Z37.7 Other multiple births, all stillborn
0.687 0.313 0.000
Z37.6 Other multiple births, some liveborn
0.687 0.313 0.000
Z37.5 Other multiple births, all liveborn
0.687 0.313 0.000
Z37.4 Twins, both stillborn
0.687 0.313 0.000
Z37.3 Twins, one liveborn and one stillborn
0.687 0.313 0.000
Z37.1 Single stillbirth
0.687 0.313 0.000
I45 Other conduction disorders
0.686 0.314 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.684 0.316 0.000
M76 Enthesopathies of lower limb, excluding foot
0.683 0.316 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.683 0.316 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.684 0.316 0.000
I49 Other cardiac arrhythmias
0.682 0.318 0.000
M84 Disorders of continuity of bone
0.682 0.318 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.682 0.318 0.000
Z72 Problems related to lifestyle
0.680 0.320 0.000
G25.3 Myoclonus
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.677 0.322 0.000
H91.9 Hearing loss, unspecified
0.676 0.324 0.000
S40-S49 Injuries to the shoulder and upper arm
0.676 0.324 0.000
O16 Unspecified maternal hypertension
0.676 0.324 0.000
M89 Other disorders of bone
0.675 0.325 0.000
B95-B98 Bacterial, viral and other infectious agents
0.674 0.326 0.000
I44 Atrioventricular and left bundle-branch block
0.674 0.326 0.000
O66 Other obstructed labour
0.674 0.326 0.000
G20 Parkinson's disease
0.674 0.326 0.000
Z88.2 Personal history of allergy to sulphonamides
0.674 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.673 0.326 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.673 0.327 0.000
S60-S69 Injuries to the wrist and hand
0.672 0.328 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
M75.8 Other shoulder lesions
0.669 0.331 0.000
M75.9 Shoulder lesion, unspecified
0.669 0.331 0.000
I31 Other diseases of pericardium
0.667 0.333 0.000
Z93.6 Other artificial openings of urinary tract status
0.667 0.333 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.666 0.334 0.000
I36 Nonrheumatic tricuspid valve disorders
0.666 0.334 0.000
J15.1 Pneumonia due to Pseudomonas
0.666 0.334 0.000
J17 Pneumonia in diseases classified elsewhere
0.665 0.335 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.665 0.335 0.000
J12 Viral pneumonia, not elsewhere classified
0.665 0.335 0.000
J11 Influenza, virus not identified
0.665 0.335 0.000
J10 Influenza due to identified influenza virus
0.665 0.335 0.000
J14 Pneumonia due to Haemophilus influenzae
0.665 0.335 0.000
J09 Influenza due to certain identified influenza virus
0.665 0.335 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.664 0.336 0.000
M47.9 Spondylosis, unspecified
0.664 0.336 0.000
I38 Endocarditis, valve unspecified
0.662 0.338 0.000
I30 Acute pericarditis
0.661 0.338 0.000
M71 Other bursopathies
0.661 0.339 0.000
G44 Other headache syndromes
0.660 0.340 0.000
I08 Multiple valve diseases
0.660 0.340 0.000
Z93.3 Colostomy status
0.660 0.340 0.000
N10-N16 Renal tubulo-interstitial diseases
0.660 0.340 0.000
I95.9 Hypotension, unspecified
0.660 0.340 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G96 Other disorders of central nervous system
0.660 0.340 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.660 0.340 0.000
G90 Disorders of autonomic nervous system
0.660 0.340 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G92 Toxic encephalopathy
0.660 0.340 0.000
I77 Other disorders of arteries and arterioles
0.659 0.341 0.000
Z97.4 Presence of external hearing-aid
0.658 0.342 0.000
Z97.3 Presence of spectacles and contact lenses
0.658 0.342 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.658 0.342 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.658 0.342 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.658 0.342 0.000
J18.8 Other pneumonia, organism unspecified
0.658 0.342 0.000
J18.2 Hypostatic pneumonia, unspecified
0.658 0.342 0.000
M85 Other disorders of bone density and structure
0.656 0.344 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.656 0.344 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.656 0.344 0.000
O47.0 False labour before 37 completed weeks of gestation
0.655 0.344 0.000
B35-B49 Mycoses
0.655 0.345 0.000
I71.0 Dissection of aorta [any part]
0.654 0.346 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.653 0.347 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.653 0.347 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.653 0.347 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.653 0.347 0.000
I65.1 Occlusion and stenosis of basilar artery
0.653 0.347 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.653 0.347 0.000
G93.4 Encephalopathy, unspecified
0.652 0.348 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.652 0.348 0.000
Z93.0 Tracheostomy status
0.651 0.349 0.000
M20-M25 Other joint disorders
0.651 0.349 0.000
M49 Spondylopathies in diseases classified elsewhere
0.649 0.350 0.000
M05-M14 Inflammatory polyarthropathies
0.649 0.351 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.648 0.352 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.647 0.353 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.645 0.355 0.000
S70 Superficial injury of hip and thigh
0.645 0.355 0.000
M79.0 Rheumatism, unspecified
0.644 0.355 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.643 0.356 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.643 0.357 0.000
G93.0 Cerebral cysts
0.643 0.357 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.642 0.358 0.000
Z34.8 Supervision of other normal pregnancy
0.641 0.359 0.000
S00-S09 Injuries to the head
0.641 0.359 0.000
G81 Hemiplegia
0.640 0.360 0.000
O44.1 Placenta praevia with haemorrhage
0.639 0.361 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.638 0.362 0.000
G93.8 Other specified disorders of brain
0.638 0.362 0.000
G93.7 Reye's syndrome
0.638 0.362 0.000
G93.6 Cerebral oedema
0.638 0.362 0.000
G93.5 Compression of brain
0.638 0.362 0.000
G93.2 Benign intracranial hypertension
0.638 0.362 0.000
J18.0 Bronchopneumonia, unspecified
0.638 0.362 0.000
M45 Ankylosing spondylitis
0.637 0.363 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.636 0.364 0.000
B65-B83 Helminthiases
0.636 0.364 0.000
N25-N29 Other disorders of kidney and ureter
0.635 0.364 0.000
N20.2 Calculus of kidney with calculus of ureter
0.635 0.365 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.635 0.365 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.634 0.366 0.000
Q80-Q89 Other congenital malformations
0.633 0.367 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.633 0.367 0.000
G24 Dystonia
0.633 0.367 0.000
G23 Other degenerative diseases of basal ganglia
0.633 0.367 0.000
G21 Secondary Parkinsonism
0.633 0.367 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.633 0.367 0.000
G22 Parkinsonism in diseases classified elsewhere
0.633 0.367 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.631 0.369 0.000
J44 Other chronic obstructive pulmonary disease
0.631 0.369 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.630 0.369 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.630 0.370 0.000
Z97.8 Presence of other specified devices
0.630 0.370 0.000
M47.89 Other spondylosis (Site unspecified)
0.629 0.370 0.000
T79-T79 Certain early complications of trauma
0.628 0.372 0.000
M47.1 Other spondylosis with myelopathy
0.628 0.372 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.628 0.372 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.628 0.372 0.000
G30 Alzheimer's disease
0.627 0.372 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.628 0.372 0.000
I70 Atherosclerosis
0.627 0.372 0.000
O82 Single delivery by Caesarean section
0.626 0.374 0.000
N23 Unspecified renal colic
0.626 0.374 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.625 0.375 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.625 0.375 0.000
I99 Other and unspecified disorders of circulatory system
0.625 0.375 0.000
O63.1 Prolonged second stage (of labour)
0.625 0.375 0.000
S72.3 Fracture of shaft of femur
0.624 0.376 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.623 0.377 0.000
H92 Otalgia and effusion of ear
0.622 0.377 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.622 0.378 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.622 0.378 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.622 0.378 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.622 0.378 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.622 0.378 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.622 0.378 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.622 0.378 0.000
O70.2 Third degree perineal laceration during delivery
0.622 0.378 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.622 0.378 0.000
Z93.9 Artificial opening status, unspecified
0.622 0.378 0.000
Z93.8 Other artificial opening status
0.622 0.378 0.000
Z93.5 Cystostomy status
0.622 0.378 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.622 0.378 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.621 0.379 0.000
T33-T35 Frostbite
0.620 0.379 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.620 0.379 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.620 0.379 0.000
T00-T07 Injuries involving multiple body regions
0.620 0.379 0.000
S10-S19 Injuries to the neck
0.620 0.379 0.000
I52 Other heart disorders in diseases classified elsewhere
0.620 0.380 0.000
I48 Atrial fibrillation and flutter
0.620 0.380 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.620 0.380 0.000
I41 Myocarditis in diseases classified elsewhere
0.620 0.380 0.000
I40 Acute myocarditis
0.620 0.380 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.620 0.380 0.000
I37 Pulmonary valve disorders
0.620 0.380 0.000
I32 Pericarditis in diseases classified elsewhere
0.620 0.380 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.619 0.381 0.000
I24.1 Dressler's syndrome
0.618 0.382 0.000
J43 Emphysema
0.618 0.382 0.000
I47 Paroxysmal tachycardia
0.618 0.382 0.000
O72 Postpartum haemorrhage
0.617 0.383 0.000
O84 Multiple delivery
0.616 0.384 0.000
O83 Other assisted single delivery
0.616 0.384 0.000
O81 Single delivery by forceps and vacuum extractor
0.616 0.384 0.000
H61.3 Acquired stenosis of external ear canal
0.615 0.385 0.000
I60 Subarachnoid haemorrhage
0.615 0.385 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.613 0.387 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.613 0.387 0.000
M47.84 Other spondylosis (Thoracic region)
0.613 0.387 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.613 0.387 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.613 0.387 0.000
N20.9 Urinary calculus, unspecified
0.613 0.387 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.612 0.388 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.612 0.388 0.000
I45.8 Other specified conduction disorders
0.612 0.388 0.000
H74 Other disorders of middle ear and mastoid
0.612 0.388 0.000
I73 Other peripheral vascular diseases
0.610 0.390 0.000
O00-O08 Pregnancy with abortive outcome
0.610 0.390 0.000
I46.0 Cardiac arrest with successful resuscitation
0.609 0.391 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.609 0.391 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.609 0.391 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.608 0.392 0.000
I27.0 Primary pulmonary hypertension
0.608 0.392 0.000
I09 Other rheumatic heart diseases
0.607 0.393 0.000
I06 Rheumatic aortic valve diseases
0.607 0.393 0.000
Z99.1 Dependence on respirator
0.607 0.393 0.000
B25-B34 Other viral diseases
0.607 0.393 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.606 0.394 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.606 0.394 0.000
B15-B19 Viral hepatitis
0.605 0.395 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.605 0.395 0.000
G44.2 Tension-type headache
0.605 0.395 0.000
M80 Osteoporosis with pathological fracture
0.604 0.396 0.000
H73 Other disorders of tympanic membrane
0.604 0.396 0.000
N21 Calculus of lower urinary tract
0.604 0.396 0.000
M46 Other inflammatory spondylopathies
0.602 0.398 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.601 0.399 0.000
H90 Conductive and sensorineural hearing loss
0.601 0.399 0.000
G25.0 Essential tremor
0.600 0.400 0.000
I33 Acute and subacute endocarditis
0.600 0.400 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.599 0.400 0.000
H70 Mastoiditis and related conditions
0.599 0.400 0.000
H69 Other disorders of Eustachian tube
0.599 0.400 0.000
H68 Eustachian salpingitis and obstruction
0.599 0.400 0.000
H67 Otitis media in diseases classified elsewhere
0.599 0.400 0.000
I34 Nonrheumatic mitral valve disorders
0.599 0.401 0.000
M86 Osteomyelitis
0.598 0.402 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.598 0.402 0.000
O62.3 Precipitate labour
0.598 0.402 0.000
O70.9 Perineal laceration during delivery, unspecified
0.597 0.402 0.000
O70.3 Fourth degree perineal laceration during delivery
0.597 0.402 0.000
O70.1 Second degree perineal laceration during delivery
0.597 0.403 0.000
S51 Open wound of forearm
0.597 0.403 0.000
O23 Infections of genito-urinary tract in pregnancy
0.596 0.404 0.000
I51 Complications and ill-defined descriptions of heart disease
0.596 0.404 0.000
M79.8 Other specified soft tissue disorders
0.596 0.404 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.595 0.405 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.595 0.405 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.595 0.405 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.595 0.405 0.000
I67.2 Cerebral atherosclerosis
0.594 0.406 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.593 0.406 0.000
T90 Sequelae of injuries of head
0.593 0.407 0.000
M77.9 Enthesopathy, unspecified
0.593 0.407 0.000
Z76 Persons encountering health services in other circumstances
0.593 0.407 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.593 0.407 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.592 0.408 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.591 0.409 0.000
N00-N08 Glomerular diseases
0.590 0.410 0.000
O36.9 Maternal care for foetal problem, unspecified
0.590 0.410 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.590 0.410 0.000
O36.4 Maternal care for intra-uterine death
0.590 0.410 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.590 0.410 0.000
O36.2 Maternal care for hydrops foetalis
0.590 0.410 0.000
O36.1 Maternal care for other isoimmunisation
0.590 0.410 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.589 0.411 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.589 0.411 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.589 0.411 0.000
O30.9 Multiple gestation, unspecified
0.588 0.412 0.000
O30.8 Other multiple gestation
0.588 0.412 0.000
O30.2 Quadruplet pregnancy
0.588 0.412 0.000
O30.1 Triplet pregnancy
0.588 0.412 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.587 0.413 0.000
O36.6 Maternal care for excessive foetal growth
0.587 0.413 0.000
M83 Adult osteomalacia
0.587 0.413 0.000
M82 Osteoporosis in diseases classified elsewhere
0.587 0.413 0.000
I63.8 Other cerebral infarction
0.586 0.414 0.000
A80-A89 Viral infections of the central nervous system
0.586 0.414 0.000
I61.8 Other intracerebral haemorrhage
0.586 0.414 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.586 0.414 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.586 0.414 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.586 0.414 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.586 0.414 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.586 0.414 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.586 0.414 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.586 0.414 0.000
I07 Rheumatic tricuspid valve diseases
0.586 0.414 0.000
J00-J06 Acute upper respiratory infections
0.586 0.414 0.000
I49.8 Other specified cardiac arrhythmias
0.586 0.414 0.000
M47.2 Other spondylosis with radiculopathy
0.585 0.415 0.000
I46.9 Cardiac arrest, unspecified
0.585 0.415 0.000
N13 Obstructive and reflux uropathy
0.585 0.415 0.000
F20 Schizophrenia
0.584 0.415 0.000
I72.3 Aneurysm of iliac artery
0.584 0.415 0.000
I42 Cardiomyopathy
0.584 0.416 0.000
Z94 Transplanted organ and tissue status
0.583 0.417 0.000
I05.1 Rheumatic mitral insufficiency
0.583 0.417 0.000
O15 Eclampsia
0.582 0.418 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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