TreeWAS – Variant ID: rs74157220

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.261	0.739
M20-M25 Other joint disorders	0.249	0.751
M45-M49 Spondylopathies	0.241	0.759
M05-M14 Inflammatory polyarthropathies	0.237	0.763
M80-M85 Disorders of bone density and structure	0.232	0.768
M86-M90 Other osteopathies	0.231	0.769
D37-D48 Neoplasms of uncertain or unknown behaviour	0.231	0.769
Chapter II Neoplasms	0.230	0.770
# Top node	0.229	0.771
Chapter XI Diseases of the digestive system	0.228	0.772
K90-K93 Other diseases of the digestive system	0.227	0.773
M23 Internal derangement of knee	0.225	0.775
K92 Other diseases of digestive system	0.222	0.778
D00-D09 In situ neoplasms	0.219	0.781
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.218	0.782
M33 Dermatopolymyositis	0.217	0.783
M06 Other rheumatoid arthritis	0.216	0.784
M34 Systemic sclerosis	0.215	0.785
M48 Other spondylopathies	0.214	0.786
Chapter XX External causes of morbidity and mortality	0.214	0.786
M21 Other acquired deformities of limbs	0.212	0.787
K40-K46 Hernia	0.212	0.788
K92.1 Melaena	0.212	0.788
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.210	0.790
M40-M43 Deforming dorsopathies	0.209	0.791
M65-M68 Disorders of synovium and tendon	0.208	0.792
M70-M79 Other soft tissue disorders	0.205	0.795
M47 Spondylosis	0.205	0.795
K44 Diaphragmatic hernia	0.205	0.795
M89 Other disorders of bone	0.204	0.796
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.203	0.797
K92.0 Haematemesis	0.203	0.797
M06.9 Rheumatoid arthritis, unspecified	0.201	0.799
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.201	0.799
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.200	0.799
M80 Osteoporosis with pathological fracture	0.199	0.800
Chapter IV Endocrine, nutritional and metabolic diseases	0.199	0.801
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.199	0.801
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.198	0.802
D03 Melanoma in situ	0.196	0.804
M48.0 Spinal stenosis	0.195	0.805
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.195	0.805
D37.4 Colon	0.194	0.806
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.194	0.806
K81 Cholecystitis	0.194	0.806
M23.2 Derangement of meniscus due to old tear or injury	0.192	0.808
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.192	0.808
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.191	0.809
M84 Disorders of continuity of bone	0.190	0.810
D05 Carcinoma in situ of breast	0.189	0.811
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.189	0.811
M24 Other specific joint derangements	0.189	0.811
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.188	0.812
M91-M94 Chondropathies	0.187	0.813
M60-M63 Disorders of muscles	0.187	0.813
M00-M03 Infectious arthropathies	0.187	0.813
K70-K77 Diseases of liver	0.187	0.813
Chapter X Diseases of the respiratory system	0.187	0.813
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.186	0.814
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.186	0.814
K81.1 Chronic cholecystitis	0.185	0.815
D45 Polycythaemia vera	0.184	0.815
M89.9 Disorder of bone, unspecified	0.184	0.816
M23.4 Loose body in knee	0.184	0.816
C51-C58 Malignant neoplasms of female genital organs	0.184	0.816
M47.8 Other spondylosis	0.184	0.816
C40-C41 Malignant neoplasms of bone and articular cartilage	0.183	0.817
M07 Psoriatic and enteropathic arthropathies	0.183	0.817
M86 Osteomyelitis	0.182	0.817
Chapter XXII Codes for special purposes	0.181	0.819
M33.2 Polymyositis	0.180	0.820
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.180	0.820
M33.1 Other dermatomyositis	0.179	0.821
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.179	0.821
M85 Other disorders of bone density and structure	0.179	0.821
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.178	0.821
M32 Systemic lupus erythematosus	0.178	0.821
M30 Polyarteritis nodosa and related conditions	0.178	0.821
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.179	0.821
M34.1 CR(E)ST syndrome	0.178	0.822
M46 Other inflammatory spondylopathies	0.178	0.822
M43 Other deforming dorsopathies	0.178	0.822
E20-E35 Disorders of other endocrine glands	0.176	0.824
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.175	0.825
T66-T78 Other and unspecified effects of external causes	0.175	0.825
M05 Seropositive rheumatoid arthritis	0.175	0.825
M48.02 Spinal stenosis (Cervical region)	0.175	0.825
D37.6 Liver, gallbladder and bile ducts	0.174	0.826
K91.3 Postoperative intestinal obstruction	0.174	0.826
M34.9 Systemic sclerosis, unspecified	0.174	0.826
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.173	0.827
M49 Spondylopathies in diseases classified elsewhere	0.173	0.827
D09 Carcinoma in situ of other and unspecified sites	0.173	0.827
Chapter I Certain infectious and parasitic diseases	0.173	0.827
T36-T50 Poisoning by drugs, medicaments and biological substances	0.173	0.827
T93 Sequelae of injuries of lower limb	0.172	0.828
E70-E90 Metabolic disorders	0.172	0.828
D37.5 Rectum	0.171	0.829
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.171	0.829
M80.0 Postmenopausal osteoporosis with pathological fracture	0.170	0.830
D37.7 Other digestive organs	0.170	0.830
M23.5 Chronic instability of knee	0.170	0.830
M14 Arthropathies in other diseases classified elsewhere	0.170	0.830
M12 Other specific arthropathies	0.170	0.830
M09 Juvenile arthritis in diseases classified elsewhere	0.170	0.830
M08 Juvenile arthritis	0.170	0.830
M10 Gout	0.170	0.830
K91.0 Vomiting following gastro-intestinal surgery	0.170	0.830
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.169	0.831
K81.0 Acute cholecystitis	0.169	0.831
C43-C44 Melanoma and other malignant neoplasms of skin	0.169	0.831
D46 Myelodysplastic syndromes	0.168	0.831
D41.4 Bladder	0.168	0.832
D03.3 Melanoma in situ of other and unspecified parts of face	0.168	0.832
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.168	0.832
M88 Paget's disease of bone [osteitis deformans]	0.167	0.833
M23.8 Other internal derangements of knee	0.167	0.833
S20-S29 Injuries to the thorax	0.167	0.833
M83 Adult osteomalacia	0.167	0.833
M82 Osteoporosis in diseases classified elsewhere	0.167	0.833
M25 Other joint disorders, not elsewhere classified	0.167	0.833
J95-J99 Other diseases of the respiratory system	0.167	0.833
M13 Other arthritis	0.166	0.834
X50-X57 Overexertion, travel and privation	0.166	0.834
M90 Osteopathies in diseases classified elsewhere	0.166	0.834
M21.1 Varus deformity, not elsewhere classified	0.166	0.834
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.166	0.834
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.166	0.834
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.166	0.834
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.166	0.834
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.166	0.834
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.166	0.834
M77 Other enthesopathies	0.166	0.834
M11 Other crystal arthropathies	0.165	0.835
C64-C68 Malignant neoplasms of urinary tract	0.165	0.835
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.165	0.835
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.165	0.835
M22 Disorders of patella	0.165	0.835
M21.3 Wrist or foot drop (acquired)	0.165	0.835
K86 Other diseases of pancreas	0.165	0.835
E16 Other disorders of pancreatic internal secretion	0.165	0.835
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.165	0.835
Y60-Y69 Misadventures to patients during surgical and medical care	0.165	0.835
M45 Ankylosing spondylitis	0.165	0.835
Chapter XVI Certain conditions originating in the perinatal period	0.165	0.835
M67 Other disorders of synovium and tendon	0.164	0.836
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.164	0.836
D07 Carcinoma in situ of other and unspecified genital organs	0.164	0.836
K43 Ventral hernia	0.163	0.837
K93 Disorders of other digestive organs in diseases classified elsewhere	0.163	0.837
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.163	0.837
S10-S19 Injuries to the neck	0.162	0.838
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.162	0.838
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.162	0.838
M31 Other necrotising vasculopathies	0.162	0.838
K42 Umbilical hernia	0.162	0.838
M23.3 Other meniscus derangements	0.162	0.838
M23.9 Internal derangement of knee, unspecified	0.162	0.838
M23.6 Other spontaneous disruption of ligament(s) of knee	0.162	0.838
M23.1 Discoid meniscus (congenital)	0.162	0.838
M23.0 Cystic meniscus	0.162	0.838
D05.9 Carcinoma in situ of breast, unspecified	0.161	0.838
M87 Osteonecrosis	0.161	0.839
J09-J18 Influenza and pneumonia	0.161	0.839
K50-K52 Noninfective enteritis and colitis	0.161	0.839
K45 Other abdominal hernia	0.161	0.839
J80-J84 Other respiratory diseases principally affecting the interstitium	0.161	0.839
D06 Carcinoma in situ of cervix uteri	0.161	0.839
M15-M19 Arthrosis	0.160	0.840
K11 Diseases of salivary glands	0.160	0.840
T91 Sequelae of injuries of neck and trunk	0.160	0.840
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.160	0.840
K92.8 Other specified diseases of digestive system	0.160	0.840
K92.2 Gastro-intestinal haemorrhage, unspecified	0.159	0.841
M21.0 Valgus deformity, not elsewhere classified	0.159	0.841
S70-S79 Injuries to the hip and thigh	0.159	0.841
W20-W49 Exposure to inanimate mechanical forces	0.159	0.841
Y84.2 Radiological procedure and radiotherapy	0.159	0.841
Y83.6 Removal of other organ (partial) (total)	0.159	0.841
K09 Cysts of oral region, not elsewhere classified	0.159	0.841
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.159	0.841
A00-A09 Intestinal infectious diseases	0.159	0.841
T15-T19 Effects of foreign body entering through natural orifice	0.158	0.842
K46 Unspecified abdominal hernia	0.158	0.842
M89.94 Disorder of bone, unspecified (Hand)	0.158	0.842
C45 Mesothelioma	0.158	0.842
M65 Synovitis and tenosynovitis	0.158	0.842
D02 Carcinoma in situ of middle ear and respiratory system	0.157	0.843
D01 Carcinoma in situ of other and unspecified digestive organs	0.157	0.843
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.157	0.843
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.157	0.843
K70 Alcoholic liver disease	0.157	0.843
D48.1 Connective and other soft tissue	0.157	0.843
K82 Other diseases of gallbladder	0.157	0.843
M81 Osteoporosis without pathological fracture	0.157	0.843
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.156	0.844
D37.9 Digestive organ, unspecified	0.156	0.844
D37.3 Appendix	0.156	0.844
D37.2 Small intestine	0.156	0.844
D37.1 Stomach	0.156	0.844
D37.0 Lip, oral cavity and pharynx	0.156	0.844
M47.1 Other spondylosis with myelopathy	0.156	0.844
K65-K67 Diseases of peritoneum	0.156	0.844
M33.9 Dermatopolymyositis, unspecified	0.156	0.844
M33.0 Juvenile dermatomyositis	0.156	0.844
C43 Malignant melanoma of skin	0.156	0.844
S90-S99 Injuries to the ankle and foot	0.156	0.844
E16.2 Hypoglycaemia, unspecified	0.155	0.845
D03.7 Melanoma in situ of lower limb, including hip	0.155	0.845
M43.1 Spondylolisthesis	0.155	0.845
M06.8 Other specified rheumatoid arthritis	0.155	0.845
M06.4 Inflammatory polyarthropathy	0.155	0.845
M06.3 Rheumatoid nodule	0.155	0.845
M06.2 Rheumatoid bursitis	0.155	0.845
M06.1 Adult-onset Still's disease	0.155	0.845
C54 Malignant neoplasm of corpus uteri	0.155	0.845
M48.09 Spinal stenosis (Site unspecified)	0.155	0.845
Q50-Q56 Congenital malformations of genital organs	0.154	0.845
M23.49 Loose body in knee-Unspec lig/men	0.154	0.846
M80.9 Unspecified osteoporosis with pathological fracture	0.154	0.846
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.154	0.846
M34.8 Other forms of systemic sclerosis	0.154	0.846
M34.2 Systemic sclerosis induced by drugs and chemicals	0.154	0.846
M34.0 Progressive systemic sclerosis	0.154	0.846
M06.0 Seronegative rheumatoid arthritis	0.154	0.846
E86 Volume depletion	0.154	0.846
M48.9 Spondylopathy, unspecified	0.153	0.846
M48.8 Other specified spondylopathies	0.153	0.846
M48.5 Collapsed vertebra, not elsewhere classified	0.153	0.846
M48.4 Fatigue fracture of vertebra	0.153	0.846
M48.3 Traumatic spondylopathy	0.153	0.846
M48.2 Kissing spine	0.153	0.846
M48.1 Ankylosing hyperostosis [Forestier]	0.153	0.846
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.153	0.846
Y35-Y36 Legal intervention and operations of war	0.153	0.846
Y10-Y34 Event of undetermined intent	0.153	0.846
Y00-Y09 Assault	0.153	0.846
X85-X99 Assault	0.153	0.846
X60-X84 Intentional self-harm	0.153	0.846
X58-X59 Accidental exposure to other and unspecified factors	0.153	0.846
X40-X49 Accidental poisoning by and exposure to noxious substances	0.153	0.846
X30-X39 Exposure to forces of nature	0.153	0.846
X20-X29 Contact with venomous animals and plants	0.153	0.846
X10-X19 Contact with heat and hot substances	0.153	0.846
X00-X09 Exposure to smoke, fire and flames	0.153	0.846
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.153	0.846
W75-W84 Other accidental threats to breathing	0.153	0.846
W65-W74 Accidental drowning and submersion	0.153	0.846
W50-W64 Exposure to animate mechanical forces	0.153	0.846
V98-V99 Other and unspecified transport accidents	0.153	0.846
V95-V97 Air and space transport accidents	0.153	0.846
V90-V94 Water transport accidents	0.153	0.846
V80-V89 Other land transport accidents	0.153	0.846
V70-V79 Bus occupant injured in transport accident	0.153	0.846
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.153	0.846
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.153	0.846
V40-V49 Car occupant injured in transport accident	0.153	0.846
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.153	0.846
V01-V09 Pedestrian injured in transport accident	0.153	0.846
T90 Sequelae of injuries of head	0.153	0.847
M21.9 Acquired deformity of limb, unspecified	0.152	0.847
M21.8 Other specified acquired deformities of limbs	0.152	0.847
M21.7 Unequal limb length (acquired)	0.152	0.847
M21.6 Other acquired deformities of ankle and foot	0.152	0.847
M21.4 Flat foot [pes planus] (acquired)	0.152	0.847
M21.2 Flexion deformity	0.152	0.847
C83 Diffuse non-Hodgkin's lymphoma	0.152	0.847
D03.6 Melanoma in situ of upper limb, including shoulder	0.152	0.848
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.151	0.848
D48.6 Breast	0.151	0.849
K91.9 Postprocedural disorder of digestive system, unspecified	0.151	0.849
K91.5 Postcholecystectomy syndrome	0.151	0.849
K91.2 Postsurgical malabsorption, not elsewhere classified	0.151	0.849
K91.1 Postgastric surgery syndromes	0.151	0.849
Q80-Q89 Other congenital malformations	0.151	0.849
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.151	0.849
D47.2 Monoclonal gammopathy	0.151	0.849
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.151	0.849
K14 Diseases of tongue	0.150	0.849
M42 Spinal osteochondrosis	0.150	0.850
M40 Kyphosis and lordosis	0.150	0.850
K10 Other diseases of jaws	0.150	0.850
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.150	0.850
M84.1 Nonunion of fracture [pseudarthrosis]	0.150	0.850
M70 Soft tissue disorders related to use, overuse and pressure	0.150	0.850
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.150	0.850
K92.9 Disease of digestive system, unspecified	0.150	0.850
M47.82 Other spondylosis (Cervical region)	0.150	0.850
K75 Other inflammatory liver diseases	0.150	0.850
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.150	0.850
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.149	0.850
M66 Spontaneous rupture of synovium and tendon	0.149	0.850
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.149	0.851
M79 Other soft tissue disorders, not elsewhere classified	0.149	0.851
M75 Shoulder lesions	0.149	0.851
E40-E46 Malnutrition	0.149	0.851
J60-J70 Lung diseases due to external agents	0.148	0.852
M84.0 Malunion of fracture	0.148	0.852
D04 Carcinoma in situ of skin	0.148	0.852
M86.9 Osteomyelitis, unspecified	0.148	0.852
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.147	0.852
M76 Enthesopathies of lower limb, excluding foot	0.147	0.853
M73 Soft tissue disorders in diseases classified elsewhere	0.147	0.853
M71 Other bursopathies	0.147	0.853
M47.2 Other spondylosis with radiculopathy	0.147	0.853
M47.0 Anterior spinal and vertebral artery compression syndromes	0.147	0.853
V10-V19 Pedal cyclist injured in transport accident	0.147	0.853
K44.1 Diaphragmatic hernia with gangrene	0.147	0.853
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.147	0.853
C81 Hodgkin's disease	0.147	0.853
K35-K38 Diseases of appendix	0.147	0.853
M35 Other systemic involvement of connective tissue	0.147	0.853
Y84.0 Cardiac catheterisation	0.147	0.853
V20-V29 Motorcycle rider injured in transport accident	0.147	0.853
T78 Adverse effects, not elsewhere classified	0.147	0.853
D48.5 Skin	0.146	0.853
J84 Other interstitial pulmonary diseases	0.146	0.854
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.146	0.854
M89.8 Other specified disorders of bone	0.146	0.854
M89.6 Osteopathy after poliomyelitis	0.146	0.854
M89.5 Osteolysis	0.146	0.854
M89.4 Other hypertrophic osteo-arthropathy	0.146	0.854
M89.3 Hypertrophy of bone	0.146	0.854
M89.2 Other disorders of bone development and growth	0.146	0.854
M89.1 Epiphyseal arrest	0.146	0.854
M89.0 Algoneurodystrophy	0.146	0.854
T33-T35 Frostbite	0.146	0.854
T26-T28 Burns and corrosions confined to eye and internal organs	0.146	0.854
T20-T25 Burns and corrosions of external body surface, specified by site	0.146	0.854
T00-T07 Injuries involving multiple body regions	0.146	0.854
E50-E64 Other nutritional deficiencies	0.146	0.854
M24.1 Other articular cartilage disorders	0.146	0.854
B35-B49 Mycoses	0.146	0.854
M16 Coxarthrosis [arthrosis of hip]	0.145	0.855
M07.3 Other psoriatic arthropathies	0.145	0.855
T93.2 Sequelae of other fractures of lower limb	0.145	0.855
C43.5 Malignant melanoma of trunk	0.145	0.855
M47.86 Other spondylosis (Lumbar region)	0.144	0.855
M06.98 Rheumatoid arthritis, unspecified (Other)	0.144	0.856
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.144	0.856
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.144	0.856
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.144	0.856
M48.06 Spinal stenosis (Lumbar region)	0.144	0.856
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.144	0.856
Q38-Q45 Other congenital malformations of the digestive system	0.144	0.856
Q60-Q64 Congenital malformations of the urinary system	0.144	0.856
Chapter VI Diseases of the nervous system	0.143	0.857
K08 Other disorders of teeth and supporting structures	0.143	0.857
M80.8 Other osteoporosis with pathological fracture	0.143	0.857
M80.5 Idiopathic osteoporosis with pathological fracture	0.143	0.857
M80.4 Drug-induced osteoporosis with pathological fracture	0.143	0.857
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.143	0.857
M80.2 Osteoporosis of disuse with pathological fracture	0.143	0.857
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.143	0.857
J95 Postprocedural respiratory disorders, not elsewhere classified	0.143	0.857
E27 Other disorders of adrenal gland	0.143	0.857
E80 Disorders of porphyrin and bilirubin metabolism	0.143	0.857
T79-T79 Certain early complications of trauma	0.142	0.857
K76 Other diseases of liver	0.142	0.857
K04 Diseases of pulp and periapical tissues	0.142	0.858
D05.1 Intraductal carcinoma in situ	0.142	0.858
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.142	0.858
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.142	0.858
Q35-Q37 Cleft lip and cleft palate	0.142	0.858
Q30-Q34 Congenital malformations of the respiratory system	0.142	0.858
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.142	0.858
Q00-Q07 Congenital malformations of the nervous system	0.142	0.858
M41 Scoliosis	0.141	0.859
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.141	0.859
Y83.4 Other reconstructive surgery	0.141	0.859
S20 Superficial injury of thorax	0.141	0.859
D05.0 Lobular carcinoma in situ	0.141	0.859
M72 Fibroblastic disorders	0.141	0.859
D47.1 Chronic myeloproliferative disease	0.141	0.859
M47.89 Other spondylosis (Site unspecified)	0.141	0.859
D03.9 Melanoma in situ, unspecified	0.140	0.859
D03.8 Melanoma in situ of other sites	0.140	0.859
D03.4 Melanoma in situ of scalp and neck	0.140	0.859
D03.2 Melanoma in situ of ear and external auricular canal	0.140	0.859
D03.1 Melanoma in situ of eyelid, including canthus	0.140	0.859
D03.0 Melanoma in situ of lip	0.140	0.859
M47.87 Other spondylosis (Lumbosacral region)	0.140	0.859
K50 Crohn's disease [regional enteritis]	0.140	0.860
M85.8 Other specified disorders of bone density and structure	0.140	0.860
M48.07 Spinal stenosis (Lumbosacral region)	0.140	0.860
D03.5 Melanoma in situ of trunk	0.140	0.860
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.140	0.860
M48.05 Spinal stenosis (Thoracolumbar region)	0.140	0.860
M48.04 Spinal stenosis (Thoracic region)	0.140	0.860
M48.03 Spinal stenosis (Cervicothoracic region)	0.140	0.860
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.140	0.860
M48.00 Spinal stenosis (Multiple sites in spine)	0.140	0.860
C51 Malignant neoplasm of vulva	0.140	0.860
T68 Hypothermia	0.140	0.860
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.140	0.860
D48.7 Other specified sites	0.140	0.860
D48.4 Peritoneum	0.140	0.860
D48.3 Retroperitoneum	0.140	0.860
D48.2 Peripheral nerves and autonomic nervous system	0.140	0.860
D48.0 Bone and articular cartilage	0.140	0.860
J99 Respiratory disorders in diseases classified elsewhere	0.140	0.860
D09.0 Bladder	0.139	0.860
D41.9 Urinary organ, unspecified	0.139	0.860
D41.7 Other urinary organs	0.139	0.860
D41.3 Urethra	0.139	0.860
D41.2 Ureter	0.139	0.860
D41.1 Renal pelvis	0.139	0.860
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.139	0.861
K81.8 Other cholecystitis	0.139	0.861
T93.8 Sequelae of other specified injuries of lower limb	0.139	0.861
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.139	0.861
K13 Other diseases of lip and oral mucosa	0.139	0.861
D41.0 Kidney	0.139	0.861
D07.1 Vulva	0.139	0.861
K12 Stomatitis and related lesions	0.139	0.861
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.139	0.861
A09.9 Gastroenteritis and colitis of unspecified origin	0.139	0.861
M20 Acquired deformities of fingers and toes	0.139	0.861
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.138	0.861
M25.7 Osteophyte	0.138	0.862
C90 Multiple myeloma and malignant plasma cell neoplasms	0.138	0.862
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.138	0.862
Q20-Q28 Congenital malformations of the circulatory system	0.138	0.862
C02 Malignant neoplasm of other and unspecified parts of tongue	0.138	0.862
M47.80 Other spondylosis (Multiple sites in spine)	0.138	0.862
T98 Sequelae of other and unspecified effects of external causes	0.138	0.862
T95 Sequelae of burns, corrosions and frostbite	0.138	0.862
T94 Sequelae of injuries involving multiple and unspecified body regions	0.138	0.862
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.138	0.862
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.138	0.862
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.137	0.862
Y86 Sequelae of other accidents	0.137	0.863
Y88 Sequelae of surgical and medical care as external cause	0.137	0.863
K03 Other diseases of hard tissues of teeth	0.137	0.863
K00 Disorders of tooth development and eruption	0.137	0.863
K85 Acute pancreatitis	0.137	0.863
M43.16 Spondylolisthesis (Lumbar region)	0.137	0.863
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.136	0.864
M22.2 Patellofemoral disorders	0.136	0.864
M84.9 Disorder of continuity of bone, unspecified	0.136	0.864
M84.8 Other disorders of continuity of bone	0.136	0.864
M84.4 Pathological fracture, not elsewhere classified	0.136	0.864
M84.3 Stress fracture, not elsewhere classified	0.136	0.864
M84.2 Delayed union of fracture	0.136	0.864
J13 Pneumonia due to Streptococcus pneumoniae	0.136	0.864
Y84.1 Kidney dialysis	0.136	0.864
S50-S59 Injuries to the elbow and forearm	0.136	0.864
T92 Sequelae of injuries of upper limb	0.136	0.864
M75.4 Impingement syndrome of shoulder	0.136	0.864
D05.7 Other carcinoma in situ of breast	0.136	0.864
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.136	0.864
M24.4 Recurrent dislocation and subluxation of joint	0.135	0.864
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.136	0.864
M24.9 Joint derangement, unspecified	0.135	0.864
M24.8 Other specific joint derangements, not elsewhere classified	0.135	0.864
M24.7 Protrusio acetabuli	0.135	0.864
M24.6 Ankylosis of joint	0.135	0.864
M24.5 Contracture of joint	0.135	0.864
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.135	0.864
M24.2 Disorder of ligament	0.135	0.864
M24.0 Loose body in joint	0.135	0.864
K14.8 Other diseases of tongue	0.135	0.865
E87 Other disorders of fluid, electrolyte and acid-base balance	0.135	0.865
C49 Malignant neoplasm of other connective and soft tissue	0.135	0.865
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.135	0.865
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.135	0.865
C46 Kaposi's sarcoma	0.135	0.865
K91.4 Colostomy and enterostomy malfunction	0.135	0.865
K86.8 Other specified diseases of pancreas	0.135	0.865
E22 Hyperfunction of pituitary gland	0.134	0.865
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.134	0.866
M02 Reactive arthropathies	0.134	0.866
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.134	0.866
M00 Pyogenic arthritis	0.134	0.866
M63 Disorders of muscle in diseases classified elsewhere	0.134	0.866
M62 Other disorders of muscle	0.134	0.866
M61 Calcification and ossification of muscle	0.134	0.866
M60 Myositis	0.134	0.866
M94 Other disorders of cartilage	0.134	0.866
M93 Other osteochondropathies	0.134	0.866
M92 Other juvenile osteochondrosis	0.134	0.866
M91 Juvenile osteochondrosis of hip and pelvis	0.134	0.866
K77 Liver disorders in diseases classified elsewhere	0.134	0.866
K73 Chronic hepatitis, not elsewhere classified	0.134	0.866
K71 Toxic liver disease	0.134	0.866
M65.9 Synovitis and tenosynovitis, unspecified	0.134	0.866
C15-C26 Malignant neoplasms of digestive organs	0.134	0.866
C54.1 Endometrium	0.134	0.866
M77.9 Enthesopathy, unspecified	0.134	0.866
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.134	0.866
K86.1 Other chronic pancreatitis	0.134	0.866
C91 Lymphoid leukaemia	0.134	0.866
K42.9 Umbilical hernia without obstruction or gangrene	0.134	0.866
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.133	0.866
C95 Leukaemia of unspecified cell type	0.133	0.866
C94 Other leukaemias of specified cell type	0.133	0.866
C93 Monocytic leukaemia	0.133	0.866
C88 Malignant immunoproliferative diseases	0.133	0.866
C86 Other specified types of T/NK-cell lymphoma	0.133	0.866
C84 Peripheral and cutaneous T-cell lymphomas	0.133	0.866

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations