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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74303283
log Bayes Factor = 9.56504
Chromosome 7   position 129,629,340  (GRCh37) Explore rs74303283 on Ensembl!
Variant rs74303283 is part of Cluster X0278

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
S60-S69 Injuries to the wrist and hand
0.996 0.004 0.000
E86 Volume depletion
0.990 0.010 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.988 0.012 0.000
E00-E07 Disorders of thyroid gland
0.981 0.019 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.979 0.021 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
Chapter VIII Diseases of the ear and mastoid process
0.977 0.023 0.000
E89.0 Postprocedural hypothyroidism
0.974 0.026 0.000
Chapter VI Diseases of the nervous system
0.973 0.027 0.000
E04 Other non-toxic goitre
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
E10 Insulin-dependent diabetes mellitus
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
M70-M79 Other soft tissue disorders
0.965 0.035 0.000
S20-S29 Injuries to the thorax
0.964 0.036 0.000
M75 Shoulder lesions
0.960 0.040 0.000
E20-E35 Disorders of other endocrine glands
0.956 0.044 0.000
E50-E64 Other nutritional deficiencies
0.955 0.045 0.000
G20-G26 Extrapyramidal and movement disorders
0.955 0.045 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.954 0.046 0.000
S61 Open wound of wrist and hand
0.949 0.051 0.000
S64 Injury of nerves at wrist and hand level
0.945 0.055 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.942 0.058 0.000
H65-H75 Diseases of middle ear and mastoid
0.936 0.064 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.936 0.064 0.000
M75.1 Rotator cuff syndrome
0.930 0.070 0.000
S50-S59 Injuries to the elbow and forearm
0.927 0.073 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.926 0.074 0.000
E87.6 Hypokalaemia
0.925 0.075 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
E04.2 Non-toxic multinodular goitre
0.919 0.081 0.000
E14 Unspecified diabetes mellitus
0.919 0.081 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.918 0.082 0.000
S61.1 Open wound of finger(s) with damage to nail
0.916 0.084 0.000
G25 Other extrapyramidal and movement disorders
0.913 0.087 0.000
S70-S79 Injuries to the hip and thigh
0.912 0.088 0.000
E04.1 Non-toxic single thyroid nodule
0.904 0.096 0.000
S68 Traumatic amputation of wrist and hand
0.904 0.096 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.903 0.097 0.000
S64.4 Injury of digital nerve of other finger
0.902 0.098 0.000
E11 Non-insulin-dependent diabetes mellitus
0.901 0.099 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.895 0.105 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.894 0.106 0.000
M75.4 Impingement syndrome of shoulder
0.893 0.107 0.000
E10.3 With ophthalmic complications
0.890 0.110 0.000
Chapter I Certain infectious and parasitic diseases
0.885 0.115 0.000
E53 Deficiency of other B group vitamins
0.879 0.121 0.000
M75.0 Adhesive capsulitis of shoulder
0.876 0.124 0.000
E22 Hyperfunction of pituitary gland
0.867 0.133 0.000
S62 Fracture at wrist and hand level
0.866 0.134 0.000
M05-M14 Inflammatory polyarthropathies
0.865 0.135 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.862 0.138 0.000
F10.1 Harmful use
0.859 0.141 0.000
E61 Deficiency of other nutrient elements
0.859 0.141 0.000
S50 Superficial injury of forearm
0.856 0.144 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.855 0.145 0.000
E14.9 Without complications
0.854 0.146 0.000
H73 Other disorders of tympanic membrane
0.851 0.149 0.000
M13 Other arthritis
0.846 0.154 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.844 0.155 0.000
M75.2 Bicipital tendinitis
0.844 0.156 0.000
E11.3 With ophthalmic complications
0.842 0.158 0.000
G24 Dystonia
0.841 0.159 0.000
H90-H95 Other disorders of ear
0.841 0.159 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.840 0.160 0.000
M86-M90 Other osteopathies
0.839 0.161 0.000
Chapter X Diseases of the respiratory system
0.836 0.164 0.000
S22.3 Fracture of rib
0.832 0.168 0.000
V20-V29 Motorcycle rider injured in transport accident
0.831 0.169 0.000
E53.8 Deficiency of other specified B group vitamins
0.824 0.176 0.000
E89.3 Postprocedural hypopituitarism
0.822 0.178 0.000
E87.5 Hyperkalaemia
0.821 0.179 0.000
M13.9 Arthritis, unspecified
0.821 0.179 0.000
J95-J99 Other diseases of the respiratory system
0.820 0.180 0.000
F30-F39 Mood [affective] disorders
0.820 0.180 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.818 0.182 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.818 0.182 0.000
H72 Perforation of tympanic membrane
0.817 0.183 0.000
Y86 Sequelae of other accidents
0.815 0.185 0.000
E10.0 With coma
0.810 0.190 0.000
F03 Unspecified dementia
0.806 0.194 0.000
F10.2 Dependence syndrome
0.805 0.195 0.000
S61.8 Open wound of other parts of wrist and hand
0.804 0.196 0.000
E10.8 With unspecified complications
0.803 0.197 0.000
H74 Other disorders of middle ear and mastoid
0.803 0.197 0.000
J98 Other respiratory disorders
0.800 0.200 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.800 0.200 0.000
S50.9 Superficial injury of forearm, unspecified
0.799 0.201 0.000
S69 Other and unspecified injuries of wrist and hand
0.797 0.203 0.000
E04.9 Non-toxic goitre, unspecified
0.794 0.206 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.792 0.208 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
S27 Injury of other and unspecified intrathoracic organs
0.790 0.210 0.000
H73.8 Other specified disorders of tympanic membrane
0.790 0.210 0.000
M80-M85 Disorders of bone density and structure
0.789 0.211 0.000
E61.1 Iron deficiency
0.789 0.211 0.000
H80-H83 Diseases of inner ear
0.788 0.212 0.000
Q00-Q07 Congenital malformations of the nervous system
0.786 0.214 0.000
M00-M03 Infectious arthropathies
0.782 0.217 0.000
F31 Bipolar affective disorder
0.782 0.218 0.000
W50-W64 Exposure to animate mechanical forces
0.780 0.220 0.000
S51 Open wound of forearm
0.779 0.221 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.779 0.221 0.000
F10.3 Withdrawal state
0.778 0.222 0.000
W75-W84 Other accidental threats to breathing
0.778 0.222 0.000
E85 Amyloidosis
0.778 0.222 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.777 0.223 0.000
E13 Other specified diabetes mellitus
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
Q50-Q56 Congenital malformations of genital organs
0.773 0.227 0.000
E73 Lactose intolerance
0.772 0.228 0.000
V40-V49 Car occupant injured in transport accident
0.771 0.229 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.771 0.229 0.000
S22.2 Fracture of sternum
0.771 0.229 0.000
T00-T07 Injuries involving multiple body regions
0.769 0.230 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.768 0.232 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.767 0.233 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.766 0.234 0.000
E10.4 With neurological complications
0.765 0.235 0.000
S22.30 Fracture of rib (closed)
0.764 0.236 0.000
S71 Open wound of hip and thigh
0.763 0.237 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.762 0.238 0.000
F05.9 Delirium, unspecified
0.762 0.238 0.000
T98 Sequelae of other and unspecified effects of external causes
0.760 0.240 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.759 0.241 0.000
S70 Superficial injury of hip and thigh
0.759 0.241 0.000
H92 Otalgia and effusion of ear
0.758 0.242 0.000
T93 Sequelae of injuries of lower limb
0.757 0.243 0.000
B25-B34 Other viral diseases
0.756 0.244 0.000
G20 Parkinson's disease
0.756 0.244 0.000
E07 Other disorders of thyroid
0.756 0.244 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.755 0.245 0.000
X20-X29 Contact with venomous animals and plants
0.754 0.246 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.754 0.246 0.000
B99-B99 Other infectious diseases
0.754 0.246 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.752 0.248 0.000
E27 Other disorders of adrenal gland
0.750 0.250 0.000
S22.4 Multiple fractures of ribs
0.749 0.251 0.000
M77 Other enthesopathies
0.748 0.252 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.747 0.253 0.000
H90 Conductive and sensorineural hearing loss
0.746 0.254 0.000
T90 Sequelae of injuries of head
0.746 0.254 0.000
M76 Enthesopathies of lower limb, excluding foot
0.745 0.255 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.742 0.258 0.000
E11.5 With peripheral circulatory complications
0.742 0.258 0.000
F10.9 Unspecified mental and behavioural disorder
0.742 0.258 0.000
M79.2 Neuralgia and neuritis, unspecified
0.740 0.260 0.000
E11.2 With renal complications
0.739 0.261 0.000
E23 Hypofunction and other disorders of pituitary gland
0.739 0.261 0.000
S62.6 Fracture of other finger
0.738 0.262 0.000
S65 Injury of blood vessels at wrist and hand level
0.737 0.262 0.000
S22.0 Fracture of thoracic vertebra
0.736 0.264 0.000
Y85 Sequelae of transport accidents
0.736 0.264 0.000
M79.7 Fibromyalgia
0.735 0.265 0.000
E26 Hyperaldosteronism
0.734 0.265 0.000
V80-V89 Other land transport accidents
0.733 0.266 0.000
B65-B83 Helminthiases
0.733 0.267 0.000
Y95 Nosocomial condition
0.733 0.267 0.000
S72 Fracture of femur
0.733 0.267 0.000
E10.2 With renal complications
0.732 0.268 0.000
M87 Osteonecrosis
0.729 0.271 0.000
M79.1 Myalgia
0.728 0.272 0.000
J98.1 Pulmonary collapse
0.728 0.272 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.728 0.272 0.000
E87.3 Alkalosis
0.728 0.272 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.725 0.275 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.724 0.276 0.000
G24.9 Dystonia, unspecified
0.724 0.276 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.723 0.277 0.000
S20 Superficial injury of thorax
0.722 0.278 0.000
F99-F99 Unspecified mental disorder
0.721 0.279 0.000
M13.94 Arthritis, unspecified (Hand)
0.720 0.280 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.280 0.000
G60 Hereditary and idiopathic neuropathy
0.719 0.281 0.000
W20-W49 Exposure to inanimate mechanical forces
0.719 0.281 0.000
E74 Other disorders of carbohydrate metabolism
0.718 0.282 0.000
E88 Other metabolic disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.715 0.284 0.000
Q80-Q89 Other congenital malformations
0.715 0.285 0.000
M13.0 Polyarthritis, unspecified
0.715 0.285 0.000
E34 Other endocrine disorders
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.713 0.287 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.711 0.289 0.000
E10.5 With peripheral circulatory complications
0.711 0.289 0.000
T17 Foreign body in respiratory tract
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.709 0.290 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.708 0.291 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.708 0.291 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.708 0.291 0.000
E89.5 Postprocedural testicular hypofunction
0.708 0.291 0.000
E89.4 Postprocedural ovarian failure
0.708 0.291 0.000
E89.2 Postprocedural hypoparathyroidism
0.708 0.291 0.000
E89.1 Postprocedural hypoinsulinaemia
0.708 0.291 0.000
T91 Sequelae of injuries of neck and trunk
0.708 0.292 0.000
E28 Ovarian dysfunction
0.707 0.293 0.000
F01 Vascular dementia
0.705 0.295 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.705 0.295 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.703 0.296 0.000
E00 Congenital iodine-deficiency syndrome
0.703 0.296 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.703 0.296 0.000
E06 Thyroiditis
0.703 0.297 0.000
M71 Other bursopathies
0.703 0.297 0.000
F00 Dementia in Alzheimer's disease
0.703 0.297 0.000
E22.1 Hyperprolactinaemia
0.703 0.297 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
E24 Cushing's syndrome
0.702 0.297 0.000
E29 Testicular dysfunction
0.702 0.298 0.000
E87.4 Mixed disorder of acid-base balance
0.702 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.698 0.302 0.000
H69 Other disorders of Eustachian tube
0.698 0.302 0.000
H72.0 Central perforation of tympanic membrane
0.698 0.302 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.697 0.303 0.000
E04.8 Other specified non-toxic goitre
0.696 0.304 0.000
E04.0 Non-toxic diffuse goitre
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.304 0.000
Y10-Y34 Event of undetermined intent
0.695 0.304 0.000
Y00-Y09 Assault
0.695 0.304 0.000
X85-X99 Assault
0.695 0.304 0.000
X30-X39 Exposure to forces of nature
0.695 0.304 0.000
X10-X19 Contact with heat and hot substances
0.695 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.304 0.000
W65-W74 Accidental drowning and submersion
0.695 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.304 0.000
V95-V97 Air and space transport accidents
0.695 0.304 0.000
V90-V94 Water transport accidents
0.695 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.304 0.000
H81 Disorders of vestibular function
0.694 0.306 0.000
E10.7 With multiple complications
0.694 0.306 0.000
E10.6 With other specified complications
0.694 0.306 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
E14.3 With ophthalmic complications
0.693 0.307 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.693 0.307 0.000
S27.0 Traumatic pneumothorax
0.693 0.307 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.692 0.308 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.691 0.309 0.000
S26 Injury of heart
0.691 0.309 0.000
S25 Injury of blood vessels of thorax
0.691 0.309 0.000
S24 Injury of nerves and spinal cord at thorax level
0.691 0.309 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.691 0.309 0.000
S21 Open wound of thorax
0.691 0.309 0.000
Y89 Sequelae of other external causes
0.691 0.309 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.689 0.311 0.000
M75.8 Other shoulder lesions
0.688 0.312 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.687 0.313 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.687 0.313 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.686 0.314 0.000
G90-G99 Other disorders of the nervous system
0.686 0.314 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.685 0.315 0.000
E32 Diseases of thymus
0.685 0.315 0.000
E31 Polyglandular dysfunction
0.685 0.315 0.000
E30 Disorders of puberty, not elsewhere classified
0.685 0.315 0.000
E25 Adrenogenital disorders
0.685 0.315 0.000
E20 Hypoparathyroidism
0.685 0.315 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.685 0.315 0.000
E63 Other nutritional deficiencies
0.685 0.315 0.000
E56 Other vitamin deficiencies
0.685 0.315 0.000
E51 Thiamine deficiency
0.685 0.315 0.000
E50 Vitamin A deficiency
0.685 0.315 0.000
E60 Dietary zinc deficiency
0.685 0.315 0.000
E59 Dietary selenium deficiency
0.685 0.315 0.000
E58 Dietary calcium deficiency
0.685 0.315 0.000
E54 Ascorbic acid deficiency
0.685 0.315 0.000
E52 Niacin deficiency [pellagra]
0.685 0.315 0.000
G23 Other degenerative diseases of basal ganglia
0.684 0.315 0.000
G21 Secondary Parkinsonism
0.684 0.315 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.684 0.315 0.000
G22 Parkinsonism in diseases classified elsewhere
0.684 0.315 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.684 0.316 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.683 0.317 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
M85 Other disorders of bone density and structure
0.683 0.317 0.000
S80-S89 Injuries to the knee and lower leg
0.682 0.318 0.000
X50-X57 Overexertion, travel and privation
0.681 0.319 0.000
J98.8 Other specified respiratory disorders
0.680 0.320 0.000
S61.7 Multiple open wounds of wrist and hand
0.680 0.320 0.000
F10.4 Withdrawal state with delirium
0.680 0.320 0.000
Q05 Spina bifida
0.678 0.322 0.000
M40-M43 Deforming dorsopathies
0.678 0.322 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.678 0.322 0.000
S64.8 Injury of other nerves at wrist and hand level
0.678 0.322 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.678 0.322 0.000
S64.1 Injury of median nerve at wrist and hand level
0.678 0.322 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.678 0.322 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.677 0.323 0.000
E10.9 Without complications
0.677 0.323 0.000
S62.2 Fracture of first metacarpal bone
0.677 0.323 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.677 0.323 0.000
S62.4 Multiple fractures of metacarpal bones
0.677 0.323 0.000
G24.5 Blepharospasm
0.676 0.324 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.675 0.324 0.000
F02 Dementia in other diseases classified elsewhere
0.675 0.324 0.000
F09 Unspecified organic or symptomatic mental disorder
0.675 0.324 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.675 0.324 0.000
F60-F69 Disorders of adult personality and behaviour
0.674 0.326 0.000
X60-X84 Intentional self-harm
0.673 0.327 0.000
G70-G73 Diseases of myoneural junction and muscle
0.673 0.327 0.000
B35-B49 Mycoses
0.672 0.328 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.671 0.329 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.671 0.329 0.000
H70 Mastoiditis and related conditions
0.671 0.329 0.000
H68 Eustachian salpingitis and obstruction
0.671 0.329 0.000
H67 Otitis media in diseases classified elsewhere
0.671 0.329 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.671 0.329 0.000
Q35-Q37 Cleft lip and cleft palate
0.671 0.329 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.671 0.329 0.000
S50.8 Other superficial injuries of forearm
0.670 0.329 0.000
S22.1 Multiple fractures of thoracic spine
0.670 0.330 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.668 0.332 0.000
E11.6 With other specified complications
0.667 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
J98.9 Respiratory disorder, unspecified
0.666 0.334 0.000
S59 Other and unspecified injuries of forearm
0.665 0.335 0.000
S58 Traumatic amputation of forearm
0.665 0.335 0.000
S57 Crushing injury of forearm
0.665 0.335 0.000
S55 Injury of blood vessels at forearm level
0.665 0.335 0.000
S54 Injury of nerves at forearm level
0.665 0.335 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.665 0.335 0.000
S22.9 Fracture of bony thorax, part unspecified
0.664 0.336 0.000
S22.8 Fracture of other parts of bony thorax
0.664 0.336 0.000
S22.5 Flail chest
0.664 0.336 0.000
B34 Viral infection of unspecified site
0.663 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.662 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.662 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.662 0.337 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.662 0.337 0.000
G57 Mononeuropathies of lower limb
0.662 0.338 0.000
S36 Injury of intra-abdominal organs
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.662 0.338 0.000
S62.60 Fracture of other finger (closed)
0.661 0.339 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.661 0.339 0.000
M14 Arthropathies in other diseases classified elsewhere
0.661 0.339 0.000
B99 Other and unspecified infectious diseases
0.659 0.341 0.000
S22.20 Fracture of sternum (closed)
0.659 0.341 0.000
J60-J70 Lung diseases due to external agents
0.659 0.341 0.000
E14.8 With unspecified complications
0.659 0.341 0.000
E14.7 With multiple complications
0.659 0.341 0.000
E14.6 With other specified complications
0.659 0.341 0.000
E14.5 With peripheral circulatory complications
0.659 0.341 0.000
E14.4 With neurological complications
0.659 0.341 0.000
E14.2 Withrenal complications
0.659 0.341 0.000
E14.1 With ketoacidosis
0.659 0.341 0.000
E14.0 With coma
0.659 0.341 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.659 0.341 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
E87.0 Hyperosmolality and hypernatraemia
0.658 0.342 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.658 0.342 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.658 0.342 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.658 0.342 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.658 0.342 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.658 0.342 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.658 0.342 0.000
S56 Injury of muscle and tendon at forearm level
0.657 0.342 0.000
S71.1 Open wound of thigh
0.657 0.343 0.000
M87.9 Osteonecrosis, unspecified
0.657 0.343 0.000
H60-H62 Diseases of external ear
0.655 0.345 0.000
S69.9 Unspecified injury of wrist and hand
0.655 0.345 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.655 0.345 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.655 0.345 0.000
G25.5 Other chorea
0.655 0.345 0.000
G25.4 Drug-induced chorea
0.655 0.345 0.000
G25.2 Other specified forms of tremor
0.655 0.345 0.000
G25.1 Drug-induced tremor
0.655 0.345 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.654 0.346 0.000
G30-G32 Other degenerative diseases of the nervous system
0.654 0.346 0.000
S78 Traumatic amputation of hip and thigh
0.653 0.346 0.000
S77 Crushing injury of hip and thigh
0.653 0.346 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.653 0.346 0.000
S75 Injury of blood vessels at hip and thigh level
0.653 0.346 0.000
S74 Injury of nerves at hip and thigh level
0.653 0.346 0.000
E22.0 Acromegaly and pituitary gigantism
0.653 0.346 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.651 0.348 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.651 0.349 0.000
B15-B19 Viral hepatitis
0.651 0.349 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.650 0.350 0.000
M00 Pyogenic arthritis
0.650 0.350 0.000
H92.1 Otorrhoea
0.649 0.351 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.648 0.352 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.648 0.352 0.000
S68.4 Traumatic amputation of hand at wrist level
0.648 0.352 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.648 0.352 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.648 0.352 0.000
F10.8 Other mental and behavioural disorders
0.648 0.352 0.000
F10.7 Residual and late-onset psychotic disorder
0.648 0.352 0.000
F10.6 Amnesic syndrome
0.648 0.352 0.000
F10.5 Psychotic disorder
0.648 0.352 0.000
Q51 Congenital malformations of uterus and cervix
0.648 0.352 0.000
H66 Suppurative and unspecified otitis media
0.647 0.352 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.646 0.354 0.000
M89 Other disorders of bone
0.646 0.354 0.000
E11.8 With unspecified complications
0.646 0.354 0.000
E11.7 With multiple complications
0.646 0.354 0.000
E11.0 With coma
0.646 0.354 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.646 0.354 0.000
G62 Other polyneuropathies
0.645 0.355 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.643 0.357 0.000
H65 Nonsuppurative otitis media
0.643 0.357 0.000
E55 Vitamin D deficiency
0.642 0.358 0.000
F05.0 Delirium not superimposed on dementia, so described
0.642 0.358 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.642 0.358 0.000
H92.0 Otalgia
0.641 0.359 0.000
W80 Inhalation and ingestion of other objects causing obstruction of respiratory tract
0.640 0.360 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.640 0.360 0.000
S29 Other and unspecified injuries of thorax
0.640 0.360 0.000
S51.0 Open wound of elbow
0.639 0.361 0.000
J00-J06 Acute upper respiratory infections
0.639 0.361 0.000
F06.7 Mild cognitive disorder
0.639 0.361 0.000
M13.93 Arthritis, unspecified (Forearm)
0.639 0.361 0.000
H74.1 Adhesive middle ear disease
0.638 0.362 0.000
E10.1 With ketoacidosis
0.637 0.362 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.637 0.363 0.000
F11 Mental and behavioural disorders due to use of opioids
0.637 0.363 0.000
M77.1 Lateral epicondylitis
0.637 0.363 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.636 0.364 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.636 0.364 0.000
V27.4 Driver injured in traffic accident
0.635 0.365 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.635 0.365 0.000
B50-B64 Protozoal diseases
0.635 0.365 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.635 0.365 0.000
A75-A79 Rickettsioses
0.635 0.365 0.000
A70-A74 Other diseases caused by chlamydiae
0.635 0.365 0.000
A65-A69 Other spirochaetal diseases
0.635 0.365 0.000
A20-A28 Certain zoonotic bacterial diseases
0.635 0.365 0.000
A15-A19 Tuberculosis
0.635 0.365 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.635 0.365 0.000
M86 Osteomyelitis
0.635 0.365 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.634 0.365 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.634 0.366 0.000
E85.9 Amyloidosis, unspecified
0.633 0.366 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.633 0.367 0.000
S60 Superficial injury of wrist and hand
0.633 0.367 0.000
H90.3 Sensorineural hearing loss, bilateral
0.633 0.367 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.632 0.368 0.000
M11 Other crystal arthropathies
0.631 0.369 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.631 0.369 0.000
E53.9 Vitamin B deficiency, unspecified
0.630 0.370 0.000
E53.1 Pyridoxine deficiency
0.630 0.370 0.000
E53.0 Riboflavin deficiency
0.630 0.370 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.630 0.370 0.000
S10-S19 Injuries to the neck
0.630 0.370 0.000
S70.1 Contusion of thigh
0.629 0.371 0.000
S62.7 Multiple fractures of fingers
0.628 0.371 0.000
S31 Open wound of abdomen, lower back and pelvis
0.628 0.372 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.627 0.373 0.000
S51.9 Open wound of forearm, part unspecified
0.626 0.374 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.626 0.374 0.000
G50 Disorders of trigeminal nerve
0.626 0.374 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.626 0.374 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.626 0.374 0.000
J40-J47 Chronic lower respiratory diseases
0.625 0.375 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.625 0.375 0.000
S64.3 Injury of digital nerve of thumb
0.624 0.376 0.000
A80-A89 Viral infections of the central nervous system
0.624 0.376 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.624 0.376 0.000
B80 Enterobiasis
0.623 0.377 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.622 0.378 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.622 0.378 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.622 0.378 0.000
E22.8 Other hyperfunction of pituitary gland
0.622 0.378 0.000
S22.40 Multiple fractures of ribs (closed)
0.622 0.378 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.621 0.379 0.000
S62.1 Fracture of other carpal bone(s)
0.621 0.379 0.000
M65-M68 Disorders of synovium and tendon
0.621 0.379 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.620 0.380 0.000
E16 Other disorders of pancreatic internal secretion
0.620 0.380 0.000
M12 Other specific arthropathies
0.620 0.380 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.620 0.380 0.000
M08 Juvenile arthritis
0.620 0.380 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.620 0.380 0.000
H72.8 Other perforations of tympanic membrane
0.619 0.381 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.619 0.381 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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