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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74457967
log Bayes Factor = 15.8347
Chromosome 20   position 826,127  (GRCh37) Explore rs74457967 on Ensembl!
Variant rs74457967 is part of Cluster X0209

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
D10-D36 Benign neoplasms
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.988 0.012 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.987 0.013 0.000
Z51.2 Other chemotherapy
0.987 0.013 0.000
Z51 Other medical care
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.982 0.018 0.000
L03 Cellulitis
0.981 0.019 0.000
N81 Female genital prolapse
0.981 0.019 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.978 0.022 0.000
Chapter I Certain infectious and parasitic diseases
0.971 0.029 0.000
N81.2 Incomplete uterovaginal prolapse
0.970 0.030 0.000
M06 Other rheumatoid arthritis
0.963 0.037 0.000
D17 Benign lipomatous neoplasm
0.959 0.041 0.000
N17-N19 Renal failure
0.955 0.045 0.000
L03.1 Cellulitis of other parts of limb
0.951 0.049 0.000
M06.9 Rheumatoid arthritis, unspecified
0.947 0.053 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.943 0.057 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.942 0.058 0.000
B95-B98 Bacterial, viral and other infectious agents
0.940 0.060 0.000
N18 Chronic renal failure
0.937 0.063 0.000
I84 Haemorrhoids
0.936 0.064 0.000
Chapter XI Diseases of the digestive system
0.934 0.066 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.929 0.071 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.927 0.073 0.000
N40-N51 Diseases of male genital organs
0.926 0.074 0.000
K55-K64 Other diseases of intestines
0.926 0.074 0.000
I44 Atrioventricular and left bundle-branch block
0.924 0.076 0.000
K62 Other diseases of anus and rectum
0.923 0.077 0.000
L20-L30 Dermatitis and eczema
0.917 0.083 0.000
I10-I15 Hypertensive diseases
0.916 0.084 0.000
N88 Other noninflammatory disorders of cervix uteri
0.915 0.085 0.000
M20-M25 Other joint disorders
0.914 0.086 0.000
I84.9 Unspecified haemorrhoids without complication
0.912 0.088 0.000
D12.4 Descending colon
0.911 0.089 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.904 0.096 0.000
D12.2 Ascending colon
0.900 0.100 0.000
N80 Endometriosis
0.898 0.102 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.898 0.102 0.000
I47 Paroxysmal tachycardia
0.896 0.104 0.000
K62.0 Anal polyp
0.893 0.107 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.889 0.111 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.888 0.112 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.887 0.113 0.000
L50-L54 Urticaria and erythema
0.882 0.118 0.000
I34 Nonrheumatic mitral valve disorders
0.880 0.120 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.880 0.120 0.000
Chapter XX External causes of morbidity and mortality
0.880 0.120 0.000
C34 Malignant neoplasm of bronchus and lung
0.878 0.122 0.000
I49 Other cardiac arrhythmias
0.877 0.123 0.000
M35 Other systemic involvement of connective tissue
0.874 0.126 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.873 0.127 0.000
N18.9 Chronic renal failure, unspecified
0.871 0.129 0.000
D60-D64 Aplastic and other anaemias
0.869 0.131 0.000
D12.6 Colon, unspecified
0.865 0.135 0.000
Z51.1 Chemotherapy session for neoplasm
0.865 0.135 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.861 0.139 0.000
K62.1 Rectal polyp
0.860 0.140 0.000
N92 Excessive, frequent and irregular menstruation
0.859 0.141 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.858 0.142 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.858 0.142 0.000
A30-A49 Other bacterial diseases
0.856 0.144 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.854 0.146 0.000
L03.3 Cellulitis of trunk
0.854 0.146 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.850 0.150 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.849 0.151 0.000
D12.8 Rectum
0.848 0.152 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.848 0.152 0.000
I12 Hypertensive renal disease
0.847 0.153 0.000
K70-K77 Diseases of liver
0.845 0.155 0.000
Z48 Other surgical follow-up care
0.844 0.156 0.000
Z71.8 Other specified counselling
0.844 0.156 0.000
N50 Other disorders of male genital organs
0.843 0.157 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.840 0.160 0.000
N60-N64 Disorders of breast
0.839 0.161 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.838 0.162 0.000
K58 Irritable bowel syndrome
0.836 0.164 0.000
I80 Phlebitis and thrombophlebitis
0.835 0.165 0.000
I42 Cardiomyopathy
0.834 0.166 0.000
N81.4 Uterovaginal prolapse, unspecified
0.832 0.168 0.000
I85 Oesophageal varices
0.830 0.170 0.000
L30 Other dermatitis
0.828 0.172 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.827 0.173 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.827 0.173 0.000
N81.6 Rectocele
0.827 0.173 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.825 0.175 0.000
I05-I09 Chronic rheumatic heart diseases
0.823 0.177 0.000
M35.3 Polymyalgia rheumatica
0.823 0.177 0.000
I44.7 Left bundle-branch block, unspecified
0.822 0.178 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.822 0.178 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.817 0.183 0.000
M25 Other joint disorders, not elsewhere classified
0.815 0.185 0.000
L03.2 Cellulitis of face
0.815 0.185 0.000
D12.0 Caecum
0.813 0.187 0.000
N18.5 Chronic kidney disease, stage 5
0.811 0.189 0.000
D00-D09 In situ neoplasms
0.811 0.189 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.810 0.190 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.810 0.190 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.807 0.193 0.000
N88.2 Stricture and stenosis of cervix uteri
0.806 0.194 0.000
I47.2 Ventricular tachycardia
0.805 0.195 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.804 0.195 0.000
N50.8 Other specified disorders of male genital organs
0.804 0.196 0.000
I45 Other conduction disorders
0.801 0.199 0.000
I49.5 Sick sinus syndrome
0.801 0.199 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.801 0.199 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.801 0.199 0.000
N00-N08 Glomerular diseases
0.800 0.200 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.798 0.202 0.000
K62.5 Haemorrhage of anus and rectum
0.797 0.203 0.000
Z43 Attention to artificial openings
0.797 0.203 0.000
I44.0 Atrioventricular block, first degree
0.796 0.204 0.000
K62.3 Rectal prolapse
0.795 0.205 0.000
I12.0 Hypertensive renal disease with renal failure
0.795 0.205 0.000
N87 Dysplasia of cervix uteri
0.794 0.206 0.000
N86 Erosion and ectropion of cervix uteri
0.794 0.206 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.794 0.206 0.000
N25-N29 Other disorders of kidney and ureter
0.794 0.206 0.000
M10 Gout
0.793 0.207 0.000
N41 Inflammatory diseases of prostate
0.791 0.209 0.000
L53 Other erythematous conditions
0.791 0.209 0.000
N18.0 End-stage renal disease
0.790 0.210 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.786 0.214 0.000
N94.6 Dysmenorrhoea, unspecified
0.785 0.215 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.785 0.215 0.000
M45-M49 Spondylopathies
0.783 0.217 0.000
D32 Benign neoplasm of meninges
0.782 0.218 0.000
D46 Myelodysplastic syndromes
0.781 0.219 0.000
Z49 Care involving dialysis
0.781 0.219 0.000
D45 Polycythaemia vera
0.780 0.220 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.780 0.220 0.000
C64-C68 Malignant neoplasms of urinary tract
0.779 0.221 0.000
M50-M54 Other dorsopathies
0.779 0.221 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.779 0.221 0.000
C34.3 Lower lobe, bronchus or lung
0.776 0.224 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.776 0.224 0.000
N89 Other noninflammatory disorders of vagina
0.775 0.225 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.775 0.225 0.000
N95 Menopausal and other perimenopausal disorders
0.775 0.225 0.000
L08 Other local infections of skin and subcutaneous tissue
0.772 0.228 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.772 0.228 0.000
N84 Polyp of female genital tract
0.772 0.228 0.000
M13 Other arthritis
0.769 0.231 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.769 0.231 0.000
D64 Other anaemias
0.768 0.232 0.000
Z41 Procedures for purposes other than remedying health state
0.767 0.233 0.000
M80-M85 Disorders of bone density and structure
0.767 0.233 0.000
M86-M90 Other osteopathies
0.767 0.233 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.766 0.234 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.766 0.234 0.000
N18.3 Chronic kidney disease, stage 3
0.763 0.237 0.000
K63 Other diseases of intestine
0.762 0.238 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.762 0.238 0.000
Z52 Donors of organs and tissues
0.762 0.238 0.000
E70-E90 Metabolic disorders
0.759 0.241 0.000
I73 Other peripheral vascular diseases
0.758 0.242 0.000
L29 Pruritus
0.758 0.242 0.000
I34.0 Mitral (valve) insufficiency
0.756 0.244 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.755 0.245 0.000
C34.9 Bronchus or lung, unspecified
0.755 0.245 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.755 0.245 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.754 0.246 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.753 0.247 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.752 0.248 0.000
Z54 Convalescence
0.751 0.249 0.000
I30 Acute pericarditis
0.751 0.249 0.000
K90-K93 Other diseases of the digestive system
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.749 0.250 0.000
N92.6 Irregular menstruation, unspecified
0.748 0.252 0.000
Z50 Care involving use of rehabilitation procedures
0.748 0.252 0.000
D12.7 Rectosigmoid junction
0.747 0.252 0.000
N85.1 Endometrial adenomatous hyperplasia
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.746 0.254 0.000
B35-B49 Mycoses
0.746 0.254 0.000
Z51.3 Blood transfusion without reported diagnosis
0.743 0.257 0.000
Z72 Problems related to lifestyle
0.739 0.261 0.000
I87 Other disorders of veins
0.739 0.261 0.000
D36 Benign neoplasm of other and unspecified sites
0.739 0.261 0.000
N10-N16 Renal tubulo-interstitial diseases
0.739 0.261 0.000
L30.9 Dermatitis, unspecified
0.738 0.262 0.000
N45 Orchitis and epididymitis
0.738 0.262 0.000
B15-B19 Viral hepatitis
0.737 0.262 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.736 0.264 0.000
D11 Benign neoplasm of major salivary glands
0.736 0.264 0.000
K61 Abscess of anal and rectal regions
0.736 0.264 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.735 0.265 0.000
C51-C58 Malignant neoplasms of female genital organs
0.735 0.265 0.000
M35.0 Sicca syndrome [Sjogren]
0.735 0.265 0.000
Chapter VI Diseases of the nervous system
0.734 0.266 0.000
I84.2 Internal haemorrhoids without complication
0.734 0.266 0.000
N80.9 Endometriosis, unspecified
0.732 0.268 0.000
M06.0 Seronegative rheumatoid arthritis
0.731 0.269 0.000
C15-C26 Malignant neoplasms of digestive organs
0.731 0.269 0.000
I84.8 Unspecified haemorrhoids with other complications
0.730 0.270 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.730 0.270 0.000
Z42 Follow-up care involving plastic surgery
0.730 0.270 0.000
D34 Benign neoplasm of thyroid gland
0.729 0.271 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.728 0.272 0.000
M70-M79 Other soft tissue disorders
0.728 0.272 0.000
N81.9 Female genital prolapse, unspecified
0.728 0.272 0.000
L03.0 Cellulitis of finger and toe
0.728 0.272 0.000
N80.3 Endometriosis of pelvic peritoneum
0.727 0.273 0.000
W00-W19 Falls
0.727 0.273 0.000
N80.0 Endometriosis of uterus
0.726 0.274 0.000
L53.9 Erythematous condition, unspecified
0.725 0.275 0.000
A41 Other septicaemia
0.725 0.275 0.000
D10 Benign neoplasm of mouth and pharynx
0.725 0.275 0.000
I85.9 Oesophageal varices without bleeding
0.724 0.276 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.723 0.277 0.000
D18 Haemangioma and lymphangioma, any site
0.723 0.277 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.721 0.279 0.000
K62.9 Disease of anus and rectum, unspecified
0.720 0.280 0.000
N94.1 Dyspareunia
0.719 0.281 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.718 0.282 0.000
N61 Inflammatory disorders of breast
0.718 0.282 0.000
M40-M43 Deforming dorsopathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M22 Disorders of patella
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
Chapter X Diseases of the respiratory system
0.716 0.284 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.715 0.285 0.000
I34.1 Mitral (valve) prolapse
0.714 0.286 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.714 0.286 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.714 0.286 0.000
D31 Benign neoplasm of eye and adnexa
0.714 0.286 0.000
D30 Benign neoplasm of urinary organs
0.714 0.286 0.000
D29 Benign neoplasm of male genital organs
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.714 0.286 0.000
D26 Other benign neoplasms of uterus
0.714 0.286 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.714 0.286 0.000
D19 Benign neoplasm of mesothelial tissue
0.714 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.714 0.286 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.714 0.286 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I33 Acute and subacute endocarditis
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
L04 Acute lymphadenitis
0.711 0.289 0.000
L01 Impetigo
0.711 0.289 0.000
L00 Staphylococcal scalded skin syndrome
0.711 0.289 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.711 0.289 0.000
I46 Cardiac arrest
0.710 0.290 0.000
N90.4 Leukoplakia of vulva
0.710 0.290 0.000
Z44 Fitting and adjustment of external prosthetic device
0.709 0.291 0.000
M25.7 Osteophyte
0.708 0.292 0.000
Z51.8 Other specified medical care
0.708 0.292 0.000
I84.6 Residual haemorrhoidal skin tags
0.708 0.292 0.000
D12.9 Anus and anal canal
0.707 0.292 0.000
D12.1 Appendix
0.707 0.292 0.000
Z51.9 Medical care, unspecified
0.707 0.292 0.000
Z51.6 Desensitisation to allergens
0.707 0.292 0.000
C44 Other malignant neoplasms of skin
0.707 0.293 0.000
D25 Leiomyoma of uterus
0.705 0.295 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.705 0.295 0.000
M14 Arthropathies in other diseases classified elsewhere
0.704 0.296 0.000
M12 Other specific arthropathies
0.704 0.296 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
M05 Seropositive rheumatoid arthritis
0.704 0.296 0.000
L03.8 Cellulitis of other sites
0.704 0.296 0.000
N81.8 Other female genital prolapse
0.704 0.296 0.000
N81.0 Female urethrocele
0.704 0.296 0.000
D62 Acute posthaemorrhagic anaemia
0.703 0.297 0.000
I50 Heart failure
0.703 0.297 0.000
N76 Other inflammation of vagina and vulva
0.702 0.298 0.000
I88 Nonspecific lymphadenitis
0.701 0.299 0.000
I86 Varicose veins of other sites
0.701 0.299 0.000
I82 Other venous embolism and thrombosis
0.701 0.299 0.000
I81 Portal vein thrombosis
0.701 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.701 0.299 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.701 0.299 0.000
L03.9 Cellulitis, unspecified
0.700 0.300 0.000
I51 Complications and ill-defined descriptions of heart disease
0.700 0.300 0.000
I49.9 Cardiac arrhythmia, unspecified
0.700 0.300 0.000
Z60 Problems related to social environment
0.699 0.301 0.000
N60 Benign mammary dysplasia
0.699 0.301 0.000
I49.4 Other and unspecified premature depolarisation
0.698 0.301 0.000
C34.1 Upper lobe, bronchus or lung
0.698 0.302 0.000
I47.1 Supraventricular tachycardia
0.697 0.303 0.000
E83 Disorders of mineral metabolism
0.697 0.303 0.000
D64.9 Anaemia, unspecified
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.696 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.696 0.304 0.000
B65-B83 Helminthiases
0.696 0.304 0.000
B50-B64 Protozoal diseases
0.696 0.304 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.696 0.304 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.696 0.304 0.000
A80-A89 Viral infections of the central nervous system
0.696 0.304 0.000
A75-A79 Rickettsioses
0.696 0.304 0.000
A70-A74 Other diseases caused by chlamydiae
0.696 0.304 0.000
A65-A69 Other spirochaetal diseases
0.696 0.304 0.000
A20-A28 Certain zoonotic bacterial diseases
0.696 0.304 0.000
A15-A19 Tuberculosis
0.696 0.304 0.000
I31 Other diseases of pericardium
0.695 0.305 0.000
K63.5 Polyp of colon
0.695 0.305 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
M07 Psoriatic and enteropathic arthropathies
0.695 0.305 0.000
D06 Carcinoma in situ of cervix uteri
0.695 0.305 0.000
D80-D89 Certain disorders involving the immune mechanism
0.695 0.305 0.000
K74 Fibrosis and cirrhosis of liver
0.694 0.306 0.000
M24 Other specific joint derangements
0.694 0.306 0.000
I73.0 Raynaud's syndrome
0.694 0.306 0.000
K75 Other inflammatory liver diseases
0.694 0.306 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.693 0.307 0.000
M06.8 Other specified rheumatoid arthritis
0.691 0.309 0.000
M06.4 Inflammatory polyarthropathy
0.691 0.309 0.000
M06.3 Rheumatoid nodule
0.691 0.309 0.000
M06.2 Rheumatoid bursitis
0.691 0.309 0.000
M06.1 Adult-onset Still's disease
0.691 0.309 0.000
C92 Myeloid leukaemia
0.690 0.310 0.000
J30-J39 Other diseases of upper respiratory tract
0.689 0.311 0.000
I10 Essential (primary) hypertension
0.689 0.311 0.000
M11 Other crystal arthropathies
0.688 0.312 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.688 0.312 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.688 0.312 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.686 0.313 0.000
N75 Diseases of Bartholin's gland
0.685 0.315 0.000
D70 Agranulocytosis
0.683 0.317 0.000
L82 Seborrhoeic keratosis
0.683 0.317 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.682 0.318 0.000
N85.4 Malposition of uterus
0.680 0.319 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.679 0.321 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.679 0.321 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.679 0.321 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.679 0.321 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.679 0.321 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.679 0.321 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.679 0.321 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.679 0.321 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
C44.3 Skin of other and unspecified parts of face
0.679 0.321 0.000
C20 Malignant neoplasm of rectum
0.677 0.323 0.000
Z48.8 Other specified surgical follow-up care
0.677 0.323 0.000
N95.2 Postmenopausal atrophic vaginitis
0.676 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.676 0.324 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.676 0.324 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.676 0.324 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.676 0.324 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.676 0.324 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.675 0.324 0.000
N94.5 Secondary dysmenorrhoea
0.675 0.324 0.000
N94.4 Primary dysmenorrhoea
0.675 0.324 0.000
N94.3 Premenstrual tension syndrome
0.675 0.324 0.000
N94.2 Vaginismus
0.675 0.324 0.000
N94.0 Mittelschmerz
0.675 0.324 0.000
A46 Erysipelas
0.675 0.325 0.000
K70 Alcoholic liver disease
0.675 0.325 0.000
K12 Stomatitis and related lesions
0.674 0.326 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.673 0.327 0.000
I77 Other disorders of arteries and arterioles
0.673 0.327 0.000
K62.4 Stenosis of anus and rectum
0.672 0.328 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.672 0.328 0.000
E87.5 Hyperkalaemia
0.672 0.328 0.000
N18.8 Other chronic renal failure
0.672 0.328 0.000
N18.2 Chronic kidney disease, stage 2
0.672 0.328 0.000
N18.1 Chronic kidney disease, stage 1
0.672 0.328 0.000
I60-I69 Cerebrovascular diseases
0.672 0.328 0.000
N41.1 Chronic prostatitis
0.671 0.329 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.671 0.329 0.000
I84.0 Internal thrombosed haemorrhoids
0.671 0.329 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.670 0.329 0.000
N92.4 Excessive bleeding in the premenopausal period
0.669 0.331 0.000
N84.1 Polyp of cervix uteri
0.668 0.332 0.000
K50-K52 Noninfective enteritis and colitis
0.667 0.333 0.000
I44.2 Atrioventricular block, complete
0.666 0.334 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.666 0.334 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.666 0.334 0.000
C32 Malignant neoplasm of larynx
0.666 0.334 0.000
C31 Malignant neoplasm of accessory sinuses
0.666 0.334 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.666 0.334 0.000
C37 Malignant neoplasm of thymus
0.666 0.334 0.000
C33 Malignant neoplasm of trachea
0.666 0.334 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.666 0.334 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.666 0.334 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.665 0.335 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.665 0.335 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.665 0.335 0.000
Z76 Persons encountering health services in other circumstances
0.664 0.336 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.664 0.336 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.664 0.336 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.664 0.336 0.000
N46 Male infertility
0.664 0.336 0.000
N44 Torsion of testis
0.664 0.336 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.664 0.336 0.000
D69 Purpura and other haemorrhagic conditions
0.664 0.336 0.000
E20-E35 Disorders of other endocrine glands
0.664 0.336 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.664 0.336 0.000
Z72.0 Tobacco use
0.663 0.337 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.663 0.337 0.000
D61 Other aplastic anaemias
0.663 0.337 0.000
I44.6 Other and unspecified fascicular block
0.663 0.337 0.000
I44.5 Left posterior fascicular block
0.663 0.337 0.000
I44.4 Left anterior fascicular block
0.663 0.337 0.000
I44.3 Other and unspecified atrioventricular block
0.663 0.337 0.000
Z51.5 Palliative care
0.662 0.338 0.000
I38 Endocarditis, valve unspecified
0.662 0.338 0.000
K62.2 Anal prolapse
0.662 0.338 0.000
Z48.0 Attention to surgical dressings and sutures
0.661 0.339 0.000
D03 Melanoma in situ
0.660 0.339 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.661 0.339 0.000
L30.8 Other specified dermatitis
0.659 0.341 0.000
Z74 Problems related to care-provider dependency
0.659 0.341 0.000
G90-G99 Other disorders of the nervous system
0.659 0.341 0.000
N90.7 Vulvar cyst
0.659 0.341 0.000
L05 Pilonidal cyst
0.659 0.341 0.000
L28 Lichen simplex chronicus and prurigo
0.658 0.342 0.000
L25 Unspecified contact dermatitis
0.658 0.342 0.000
L24 Irritant contact dermatitis
0.658 0.342 0.000
L23 Allergic contact dermatitis
0.658 0.342 0.000
L21 Seborrhoeic dermatitis
0.658 0.342 0.000
L20 Atopic dermatitis
0.658 0.342 0.000
L26 Exfoliative dermatitis
0.658 0.342 0.000
L22 Diaper [napkin] dermatitis
0.658 0.342 0.000
N80.8 Other endometriosis
0.657 0.343 0.000
D68 Other coagulation defects
0.657 0.343 0.000
I15 Secondary hypertension
0.656 0.343 0.000
I13 Hypertensive heart and renal disease
0.656 0.343 0.000
I11 Hypertensive heart disease
0.656 0.343 0.000
M10.9 Gout, unspecified
0.656 0.344 0.000
K55 Vascular disorders of intestine
0.656 0.344 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.656 0.344 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.656 0.344 0.000
N88.3 Incompetence of cervix uteri
0.656 0.344 0.000
N88.1 Old laceration of cervix uteri
0.656 0.344 0.000
N88.0 Leukoplakia of cervix uteri
0.656 0.344 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.656 0.344 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.656 0.344 0.000
I08 Multiple valve diseases
0.655 0.345 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.655 0.345 0.000
M34 Systemic sclerosis
0.655 0.345 0.000
M33 Dermatopolymyositis
0.655 0.345 0.000
M32 Systemic lupus erythematosus
0.655 0.345 0.000
M30 Polyarteritis nodosa and related conditions
0.655 0.345 0.000
M21 Other acquired deformities of limbs
0.655 0.345 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.655 0.345 0.000
N81.3 Complete uterovaginal prolapse
0.654 0.345 0.000
I42.2 Other hypertrophic cardiomyopathy
0.654 0.345 0.000
L50 Urticaria
0.654 0.346 0.000
Z71.9 Counselling, unspecified
0.653 0.347 0.000
I44.1 Atrioventricular block, second degree
0.653 0.347 0.000
K08 Other disorders of teeth and supporting structures
0.652 0.348 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.652 0.348 0.000
Z73 Problems related to life-management difficulty
0.652 0.348 0.000
Z48.9 Surgical follow-up care, unspecified
0.651 0.349 0.000
L40-L45 Papulosquamous disorders
0.651 0.349 0.000
A49 Bacterial infection of unspecified site
0.650 0.349 0.000
N97 Female infertility
0.649 0.351 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.648 0.352 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.648 0.352 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.648 0.352 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.648 0.352 0.000
I07 Rheumatic tricuspid valve diseases
0.647 0.353 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.647 0.353 0.000
N99-N99 Other disorders of the genitourinary system
0.646 0.354 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.646 0.354 0.000
M54 Dorsalgia
0.646 0.354 0.000
N70 Salpingitis and oophoritis
0.645 0.355 0.000
N80.6 Endometriosis in cutaneous scar
0.644 0.356 0.000
N80.5 Endometriosis of intestine
0.644 0.356 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.644 0.356 0.000
N80.2 Endometriosis of Fallopian tube
0.644 0.356 0.000
L29.0 Pruritus ani
0.644 0.356 0.000
L27 Dermatitis due to substances taken internally
0.643 0.357 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.643 0.357 0.000
Y45.0 Opioids and related analgesics
0.643 0.357 0.000
W20-W49 Exposure to inanimate mechanical forces
0.642 0.357 0.000
I27 Other pulmonary heart diseases
0.642 0.358 0.000
K11 Diseases of salivary glands
0.642 0.358 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.642 0.358 0.000
I47.0 Reentry ventricular arrhythmia
0.642 0.358 0.000
I84.3 External thrombosed haemorrhoids
0.642 0.358 0.000
M25.4 Effusion of joint
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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