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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74471121
log Bayes Factor = 15.6908
Chromosome 17   position 6,108,771  (GRCh37) Explore rs74471121 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
C50-C50 Malignant neoplasm of breast
0.989 0.011 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.985 0.015 0.000
S60-S69 Injuries to the wrist and hand
0.985 0.015 0.000
Z92.3 Personal history of irradiation
0.983 0.017 0.000
C50 Malignant neoplasm of breast
0.982 0.018 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.974 0.026 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.973 0.027 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.969 0.031 0.000
G90-G99 Other disorders of the nervous system
0.960 0.040 0.000
S61 Open wound of wrist and hand
0.958 0.042 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.957 0.043 0.000
C50.9 Breast, unspecified
0.954 0.046 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.954 0.046 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.953 0.047 0.000
S00-S09 Injuries to the head
0.946 0.054 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.945 0.055 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.943 0.057 0.000
C79 Secondary malignant neoplasm of other sites
0.941 0.059 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.936 0.064 0.000
O60-O75 Complications of labour and delivery
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
Z51 Other medical care
0.931 0.069 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.930 0.070 0.000
Chapter V Mental and behavioural disorders
0.929 0.071 0.000
G40-G47 Episodic and paroxysmal disorders
0.923 0.077 0.000
Chapter VII Diseases of the eye and adnexa
0.922 0.078 0.000
C34 Malignant neoplasm of bronchus and lung
0.921 0.079 0.000
S61.0 Open wound of finger(s) without damage to nail
0.920 0.080 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.919 0.081 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.918 0.082 0.000
R50-R69 General symptoms and signs
0.916 0.084 0.000
Z80 Family history of malignant neoplasm
0.909 0.091 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.907 0.093 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.906 0.094 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.903 0.097 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.897 0.103 0.000
Z45 Adjustment and management of implanted device
0.894 0.106 0.000
Z51.1 Chemotherapy session for neoplasm
0.891 0.109 0.000
Z88.5 Personal history of allergy to narcotic agent
0.888 0.112 0.000
C50.2 Upper-inner quadrant of breast
0.888 0.112 0.000
C77.2 Intra-abdominal lymph nodes
0.884 0.116 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.882 0.118 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.881 0.119 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.877 0.123 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.877 0.123 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.869 0.131 0.000
Z51.3 Blood transfusion without reported diagnosis
0.868 0.132 0.000
C34.9 Bronchus or lung, unspecified
0.863 0.137 0.000
R41.0 Disorientation, unspecified
0.862 0.138 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.860 0.140 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.859 0.141 0.000
G93 Other disorders of brain
0.857 0.143 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.856 0.144 0.000
R51 Headache
0.856 0.144 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.855 0.145 0.000
S01 Open wound of head
0.854 0.146 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.852 0.148 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.852 0.148 0.000
R47-R49 Symptoms and signs involving speech and voice
0.847 0.152 0.000
Z45.2 Adjustment and management of vascular access device
0.845 0.155 0.000
Chapter IX Diseases of the circulatory system
0.843 0.157 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.841 0.159 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.837 0.163 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.837 0.163 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.836 0.164 0.000
C34.1 Upper lobe, bronchus or lung
0.834 0.166 0.000
S20-S29 Injuries to the thorax
0.831 0.169 0.000
D70 Agranulocytosis
0.829 0.171 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.829 0.171 0.000
C77.3 Axillary and upper limb lymph nodes
0.828 0.172 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.827 0.173 0.000
G44 Other headache syndromes
0.827 0.173 0.000
H02 Other disorders of eyelid
0.826 0.174 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.823 0.177 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.822 0.178 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.820 0.180 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.819 0.181 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.819 0.181 0.000
Z98 Other postsurgical states
0.815 0.185 0.000
C50.8 Overlapping lesion of breast
0.815 0.185 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.810 0.190 0.000
O63 Long labour
0.810 0.190 0.000
G56 Mononeuropathies of upper limb
0.809 0.191 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.808 0.192 0.000
G43 Migraine
0.808 0.192 0.000
Z99.2 Dependence on renal dialysis
0.806 0.194 0.000
M70-M79 Other soft tissue disorders
0.805 0.195 0.000
Z99.1 Dependence on respirator
0.803 0.197 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.802 0.197 0.000
C50.1 Central portion of breast
0.802 0.198 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.800 0.200 0.000
G95 Other diseases of spinal cord
0.799 0.201 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.799 0.201 0.000
Chapter XXII Codes for special purposes
0.799 0.201 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.797 0.203 0.000
Z41 Procedures for purposes other than remedying health state
0.790 0.210 0.000
R63 Symptoms and signs concerning food and fluid intake
0.788 0.212 0.000
D10-D36 Benign neoplasms
0.788 0.212 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.788 0.212 0.000
O00-O08 Pregnancy with abortive outcome
0.787 0.213 0.000
S80-S89 Injuries to the knee and lower leg
0.787 0.213 0.000
G81 Hemiplegia
0.785 0.215 0.000
C77.0 Lymph nodes of head, face and neck
0.785 0.215 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.784 0.216 0.000
C80 Malignant neoplasm without specification of site
0.784 0.216 0.000
M50-M54 Other dorsopathies
0.783 0.217 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.782 0.218 0.000
Chapter I Certain infectious and parasitic diseases
0.778 0.222 0.000
R52 Pain, not elsewhere classified
0.774 0.226 0.000
C15-C26 Malignant neoplasms of digestive organs
0.774 0.226 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.772 0.228 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.769 0.231 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.768 0.232 0.000
D60-D64 Aplastic and other anaemias
0.768 0.232 0.000
F10.2 Dependence syndrome
0.767 0.233 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.767 0.233 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.766 0.234 0.000
Z80.3 Family history of malignant neoplasm of breast
0.765 0.235 0.000
S67 Crushing injury of wrist and hand
0.765 0.235 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.764 0.236 0.000
G93.6 Cerebral oedema
0.763 0.237 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.761 0.239 0.000
S60 Superficial injury of wrist and hand
0.759 0.241 0.000
G44.2 Tension-type headache
0.757 0.243 0.000
S09 Other and unspecified injuries of head
0.756 0.244 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.756 0.244 0.000
Z99.8 Dependence on other enabling machines and devices
0.756 0.244 0.000
M20-M25 Other joint disorders
0.755 0.245 0.000
S00 Superficial injury of head
0.753 0.247 0.000
W00-W19 Falls
0.753 0.247 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.752 0.248 0.000
G41 Status epilepticus
0.752 0.248 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.751 0.249 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.750 0.250 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.748 0.252 0.000
R45 Symptoms and signs involving emotional state
0.748 0.252 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.748 0.252 0.000
S01.8 Open wound of other parts of head
0.747 0.253 0.000
I60-I69 Cerebrovascular diseases
0.747 0.253 0.000
Z93 Artificial opening status
0.746 0.253 0.000
Z99.3 Dependence on wheelchair
0.746 0.254 0.000
G96 Other disorders of central nervous system
0.745 0.254 0.000
H53-H54 Visual disturbances and blindness
0.743 0.257 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.743 0.257 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.742 0.258 0.000
R47 Speech disturbances, not elsewhere classified
0.741 0.259 0.000
L40-L45 Papulosquamous disorders
0.740 0.260 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.739 0.261 0.000
Y43 Primarily systemic agents
0.739 0.261 0.000
Z42 Follow-up care involving plastic surgery
0.738 0.262 0.000
H55-H59 Other disorders of eye and adnexa
0.737 0.263 0.000
H01 Other inflammation of eyelid
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.736 0.263 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.735 0.265 0.000
M05-M14 Inflammatory polyarthropathies
0.735 0.265 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.735 0.265 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.734 0.266 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.734 0.266 0.000
L60-L75 Disorders of skin appendages
0.733 0.267 0.000
M75 Shoulder lesions
0.732 0.268 0.000
R20 Disturbances of skin sensation
0.731 0.269 0.000
S90-S99 Injuries to the ankle and foot
0.729 0.270 0.000
O73 Retained placenta and membranes, without haemorrhage
0.729 0.271 0.000
F10.1 Harmful use
0.729 0.271 0.000
D75 Other diseases of blood and blood-forming organs
0.728 0.272 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.728 0.272 0.000
Z88.6 Personal history of allergy to analgesic agent
0.727 0.273 0.000
Z97 Presence of other devices
0.727 0.273 0.000
R50 Fever of unknown origin
0.727 0.273 0.000
C34.0 Main bronchus
0.726 0.273 0.000
D50-D53 Nutritional anaemias
0.726 0.273 0.000
T79-T79 Certain early complications of trauma
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.726 0.274 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.726 0.274 0.000
O80-O84 Delivery
0.726 0.274 0.000
G82 Paraplegia and tetraplegia
0.726 0.274 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.725 0.275 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.725 0.275 0.000
G43.9 Migraine, unspecified
0.725 0.275 0.000
H02.0 Entropion and trichiasis of eyelid
0.724 0.276 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.724 0.276 0.000
S61.1 Open wound of finger(s) with damage to nail
0.722 0.278 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.722 0.278 0.000
D23 Other benign neoplasms of skin
0.722 0.278 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.722 0.278 0.000
Z47 Other orthopaedic follow-up care
0.722 0.278 0.000
Z60 Problems related to social environment
0.722 0.278 0.000
G56.0 Carpal tunnel syndrome
0.720 0.280 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.720 0.280 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.720 0.280 0.000
Z49 Care involving dialysis
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.717 0.283 0.000
Z52 Donors of organs and tissues
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.8 Personal history of other medical treatment
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
Z92.0 Personal history of contraception
0.717 0.283 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.716 0.284 0.000
Z43 Attention to artificial openings
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
H30-H36 Disorders of choroid and retina
0.715 0.285 0.000
F10.4 Withdrawal state with delirium
0.715 0.285 0.000
I84 Haemorrhoids
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.712 0.288 0.000
C79.2 Secondary malignant neoplasm of skin
0.711 0.289 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.709 0.290 0.000
O63.1 Prolonged second stage (of labour)
0.708 0.292 0.000
S40-S49 Injuries to the shoulder and upper arm
0.707 0.292 0.000
C77.9 Lymph node, unspecified
0.707 0.293 0.000
S01.9 Open wound of head, part unspecified
0.707 0.293 0.000
S02 Fracture of skull and facial bones
0.707 0.293 0.000
G80 Infantile cerebral palsy
0.707 0.293 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.706 0.294 0.000
S65 Injury of blood vessels at wrist and hand level
0.706 0.294 0.000
S68 Traumatic amputation of wrist and hand
0.706 0.294 0.000
M86-M90 Other osteopathies
0.706 0.294 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.705 0.295 0.000
S32 Fracture of lumbar spine and pelvis
0.705 0.295 0.000
H02.4 Ptosis of eyelid
0.705 0.295 0.000
C50.6 Axillary tail of breast
0.704 0.296 0.000
C50.3 Lower-inner quadrant of breast
0.704 0.296 0.000
C50.0 Nipple and areola
0.704 0.296 0.000
R41.3 Other amnesia
0.703 0.297 0.000
M75.1 Rotator cuff syndrome
0.703 0.297 0.000
R59 Enlarged lymph nodes
0.702 0.298 0.000
R57 Shock, not elsewhere classified
0.702 0.298 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.701 0.299 0.000
S62 Fracture at wrist and hand level
0.701 0.299 0.000
R53 Malaise and fatigue
0.700 0.300 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.699 0.301 0.000
G81.9 Hemiplegia, unspecified
0.699 0.301 0.000
O85-O92 Complications predominantly related to the puerperium
0.698 0.302 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.698 0.302 0.000
Z54 Convalescence
0.697 0.302 0.000
Z44 Fitting and adjustment of external prosthetic device
0.697 0.302 0.000
M51 Other intervertebral disk disorders
0.697 0.303 0.000
G93.9 Disorder of brain, unspecified
0.696 0.304 0.000
G56.2 Lesion of ulnar nerve
0.696 0.304 0.000
Chapter VIII Diseases of the ear and mastoid process
0.695 0.305 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.695 0.305 0.000
Z29 Need for other prophylactic measures
0.694 0.306 0.000
I67 Other cerebrovascular diseases
0.694 0.306 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.694 0.306 0.000
S06 Intracranial injury
0.693 0.307 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.693 0.307 0.000
H05 Disorders of orbit
0.692 0.307 0.000
Z40 Prophylactic surgery
0.692 0.308 0.000
Z48 Other surgical follow-up care
0.692 0.308 0.000
D32 Benign neoplasm of meninges
0.692 0.308 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
R80 Isolated proteinuria
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.311 0.000
F99-F99 Unspecified mental disorder
0.689 0.311 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.688 0.312 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.688 0.312 0.000
G90 Disorders of autonomic nervous system
0.688 0.312 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.688 0.312 0.000
G92 Toxic encephalopathy
0.688 0.312 0.000
S61.7 Multiple open wounds of wrist and hand
0.687 0.313 0.000
L89 Decubitus ulcer
0.686 0.314 0.000
D80-D89 Certain disorders involving the immune mechanism
0.686 0.314 0.000
F10.0 Acute intoxication
0.686 0.314 0.000
C77.8 Lymph nodes of multiple regions
0.686 0.314 0.000
C77.4 Inguinal and lower limb lymph nodes
0.686 0.314 0.000
Z94 Transplanted organ and tissue status
0.685 0.314 0.000
R63.4 Abnormal weight loss
0.685 0.315 0.000
M65-M68 Disorders of synovium and tendon
0.685 0.315 0.000
O03 Spontaneous abortion
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.684 0.316 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.684 0.316 0.000
C32 Malignant neoplasm of larynx
0.684 0.316 0.000
C31 Malignant neoplasm of accessory sinuses
0.684 0.316 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.684 0.316 0.000
C37 Malignant neoplasm of thymus
0.684 0.316 0.000
C33 Malignant neoplasm of trachea
0.684 0.316 0.000
G91 Hydrocephalus
0.683 0.317 0.000
D55-D59 Haemolytic anaemias
0.683 0.317 0.000
G58 Other mononeuropathies
0.682 0.318 0.000
Z51.5 Palliative care
0.682 0.318 0.000
V10-V19 Pedal cyclist injured in transport accident
0.682 0.318 0.000
R40 Somnolence, stupor and coma
0.681 0.319 0.000
Z90.7 Acquired absence of genital organ(s)
0.680 0.320 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.679 0.320 0.000
L50-L54 Urticaria and erythema
0.679 0.321 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.679 0.321 0.000
S08 Traumatic amputation of part of head
0.678 0.322 0.000
S07 Crushing injury of head
0.678 0.322 0.000
S05 Injury of eye and orbit
0.678 0.322 0.000
S04 Injury of cranial nerves
0.678 0.322 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.678 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.678 0.322 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.678 0.322 0.000
Z99.4 Dependence on artificial heart
0.678 0.322 0.000
Z99.0 Dependence on aspirator
0.678 0.322 0.000
R46 Symptoms and signs involving appearance and behaviour
0.676 0.323 0.000
R43 Disturbances of smell and taste
0.676 0.323 0.000
H02.8 Other specified disorders of eyelid
0.676 0.324 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.676 0.324 0.000
L81 Other disorders of pigmentation
0.676 0.324 0.000
O72 Postpartum haemorrhage
0.675 0.325 0.000
C79.6 Secondary malignant neoplasm of ovary
0.674 0.325 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.674 0.325 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.674 0.325 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.674 0.325 0.000
T93 Sequelae of injuries of lower limb
0.674 0.325 0.000
D72 Other disorders of white blood cells
0.674 0.326 0.000
L84 Corns and callosities
0.673 0.327 0.000
C77.5 Intrapelvic lymph nodes
0.673 0.327 0.000
C50.5 Lower-outer quadrant of breast
0.673 0.327 0.000
F10.3 Withdrawal state
0.673 0.327 0.000
Chapter X Diseases of the respiratory system
0.673 0.327 0.000
S64 Injury of nerves at wrist and hand level
0.672 0.328 0.000
L10-L14 Bullous disorders
0.671 0.329 0.000
D00-D09 In situ neoplasms
0.671 0.329 0.000
Z98.8 Other specified postsurgical states
0.671 0.329 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.671 0.329 0.000
O74 Complications of anaesthesia during labour and delivery
0.671 0.329 0.000
O71 Other obstetric trauma
0.671 0.329 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.671 0.329 0.000
O66 Other obstructed labour
0.671 0.329 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.671 0.329 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.671 0.329 0.000
O62 Abnormalities of forces of labour
0.671 0.329 0.000
O61 Failed induction of labour
0.671 0.329 0.000
O60 Preterm delivery
0.671 0.329 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.670 0.330 0.000
R54 Senility
0.669 0.330 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.669 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
W50-W64 Exposure to animate mechanical forces
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V80-V89 Other land transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V40-V49 Car occupant injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.669 0.331 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.668 0.332 0.000
Z51.9 Medical care, unspecified
0.668 0.332 0.000
Z51.6 Desensitisation to allergens
0.668 0.332 0.000
M35 Other systemic involvement of connective tissue
0.668 0.332 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.667 0.333 0.000
M91-M94 Chondropathies
0.667 0.333 0.000
M60-M63 Disorders of muscles
0.667 0.333 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.666 0.333 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.666 0.334 0.000
F80-F89 Disorders of psychological development
0.666 0.334 0.000
F70-F79 Mental retardation
0.666 0.334 0.000
F60-F69 Disorders of adult personality and behaviour
0.666 0.334 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.666 0.334 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.666 0.334 0.000
M40-M43 Deforming dorsopathies
0.665 0.335 0.000
S70-S79 Injuries to the hip and thigh
0.665 0.335 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.665 0.335 0.000
O70 Perineal laceration during delivery
0.664 0.336 0.000
C18 Malignant neoplasm of colon
0.662 0.338 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.662 0.338 0.000
R52.1 Chronic intractable pain
0.662 0.338 0.000
F30-F39 Mood [affective] disorders
0.662 0.338 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.661 0.339 0.000
H10-H13 Disorders of conjunctiva
0.661 0.339 0.000
C71 Malignant neoplasm of brain
0.661 0.339 0.000
C34.8 Overlapping lesion of bronchus and lung
0.661 0.339 0.000
C34.2 Middle lobe, bronchus or lung
0.661 0.339 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.660 0.340 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.660 0.340 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.659 0.341 0.000
S37 Injury of urinary and pelvic organs
0.659 0.341 0.000
S36 Injury of intra-abdominal organs
0.659 0.341 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.659 0.341 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.659 0.341 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.659 0.341 0.000
S31 Open wound of abdomen, lower back and pelvis
0.659 0.341 0.000
Y43.3 Other antineoplastic drugs
0.659 0.341 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.658 0.341 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.658 0.341 0.000
T85.2 Mechanical complication of intraocular lens
0.658 0.341 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.658 0.341 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.658 0.341 0.000
Z50 Care involving use of rehabilitation procedures
0.658 0.342 0.000
G40 Epilepsy
0.658 0.342 0.000
R68 Other general symptoms and signs
0.657 0.343 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.657 0.343 0.000
R62 Lack of expected normal physiological development
0.657 0.343 0.000
R64 Cachexia
0.657 0.343 0.000
R58 Haemorrhage, not elsewhere classified
0.657 0.343 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.657 0.343 0.000
D10 Benign neoplasm of mouth and pharynx
0.657 0.343 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.656 0.344 0.000
Y40 Systemic antibiotics
0.655 0.345 0.000
S61.8 Open wound of other parts of wrist and hand
0.654 0.346 0.000
M25 Other joint disorders, not elsewhere classified
0.653 0.347 0.000
M45-M49 Spondylopathies
0.653 0.347 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.652 0.348 0.000
Z80.6 Family history of leukaemia
0.652 0.348 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.652 0.348 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.652 0.348 0.000
L20-L30 Dermatitis and eczema
0.652 0.348 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.650 0.349 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.650 0.349 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.650 0.350 0.000
G83 Other paralytic syndromes
0.649 0.351 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.648 0.352 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.648 0.352 0.000
R41.2 Retrograde amnesia
0.648 0.352 0.000
R41.1 Anterograde amnesia
0.648 0.352 0.000
A00-A09 Intestinal infectious diseases
0.648 0.352 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.647 0.353 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.646 0.353 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.645 0.355 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.645 0.355 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.644 0.355 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.644 0.356 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.644 0.356 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.643 0.357 0.000
D74 Methaemoglobinaemia
0.643 0.357 0.000
D73 Diseases of spleen
0.643 0.357 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.643 0.357 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.643 0.357 0.000
R00 Abnormalities of heart beat
0.642 0.358 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.642 0.358 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.641 0.358 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.641 0.359 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.641 0.359 0.000
Z45.3 Adjustment and management of implanted hearing device
0.641 0.359 0.000
Z45.1 Adjustment and management of infusion pump
0.641 0.359 0.000
G51 Facial nerve disorders
0.641 0.359 0.000
R60 Oedema, not elsewhere classified
0.640 0.360 0.000
S00.8 Superficial injury of other parts of head
0.640 0.360 0.000
R23 Other skin changes
0.639 0.361 0.000
Q60-Q64 Congenital malformations of the urinary system
0.639 0.361 0.000
D64 Other anaemias
0.639 0.361 0.000
G95.9 Disease of spinal cord, unspecified
0.639 0.361 0.000
G95.8 Other specified diseases of spinal cord
0.639 0.361 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.639 0.361 0.000
H02.3 Blepharochalasis
0.638 0.362 0.000
H01.0 Blepharitis
0.637 0.363 0.000
Z60.2 Living alone
0.636 0.364 0.000
R82 Other abnormal findings in urine
0.635 0.365 0.000
R47.1 Dysarthria and anarthria
0.635 0.365 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.634 0.366 0.000
M80-M85 Disorders of bone density and structure
0.633 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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