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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74472562
log Bayes Factor = 10.3285
Chromosome 11   position 44,762,755  (GRCh37) Explore rs74472562 on Ensembl!
Variant rs74472562 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
O60-O75 Complications of labour and delivery
0.996 0.004 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.990 0.010 0.000
Z45 Adjustment and management of implanted device
0.985 0.015 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
S00-S09 Injuries to the head
0.969 0.031 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.968 0.032 0.000
Z45.2 Adjustment and management of vascular access device
0.968 0.032 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.959 0.041 0.000
Z48 Other surgical follow-up care
0.957 0.043 0.000
M20-M25 Other joint disorders
0.957 0.043 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.957 0.043 0.000
D69 Purpura and other haemorrhagic conditions
0.953 0.047 0.000
H90-H95 Other disorders of ear
0.952 0.048 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.946 0.054 0.000
O70 Perineal laceration during delivery
0.945 0.055 0.000
Chapter I Certain infectious and parasitic diseases
0.940 0.060 0.000
Z51 Other medical care
0.938 0.062 0.000
D69.6 Thrombocytopenia, unspecified
0.937 0.063 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.933 0.067 0.000
M80-M85 Disorders of bone density and structure
0.932 0.068 0.000
Chapter VII Diseases of the eye and adnexa
0.929 0.071 0.000
C77.3 Axillary and upper limb lymph nodes
0.929 0.071 0.000
C50-C50 Malignant neoplasm of breast
0.925 0.075 0.000
Z51.1 Chemotherapy session for neoplasm
0.923 0.077 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.921 0.079 0.000
S00 Superficial injury of head
0.920 0.080 0.000
H65-H75 Diseases of middle ear and mastoid
0.919 0.081 0.000
M23 Internal derangement of knee
0.912 0.088 0.000
Z48.0 Attention to surgical dressings and sutures
0.911 0.089 0.000
H60-H62 Diseases of external ear
0.911 0.089 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.909 0.091 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.906 0.094 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.906 0.094 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.906 0.094 0.000
O70.1 Second degree perineal laceration during delivery
0.904 0.096 0.000
M80 Osteoporosis with pathological fracture
0.903 0.097 0.000
H52 Disorders of refraction and accommodation
0.901 0.099 0.000
M25 Other joint disorders, not elsewhere classified
0.895 0.105 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.894 0.106 0.000
Z51.5 Palliative care
0.893 0.107 0.000
C79 Secondary malignant neoplasm of other sites
0.891 0.109 0.000
S06 Intracranial injury
0.891 0.109 0.000
Z45.8 Adjustment and management of other implanted devices
0.885 0.115 0.000
S00.9 Superficial injury of head, part unspecified
0.884 0.116 0.000
Z04 Examination and observation for other reasons
0.882 0.118 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.881 0.119 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.877 0.123 0.000
C15 Malignant neoplasm of oesophagus
0.876 0.124 0.000
H30-H36 Disorders of choroid and retina
0.873 0.127 0.000
C18 Malignant neoplasm of colon
0.873 0.127 0.000
C50 Malignant neoplasm of breast
0.872 0.128 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.866 0.134 0.000
M65-M68 Disorders of synovium and tendon
0.859 0.141 0.000
H52.1 Myopia
0.859 0.141 0.000
H93 Other disorders of ear, not elsewhere classified
0.855 0.145 0.000
C77.9 Lymph node, unspecified
0.853 0.147 0.000
A30-A49 Other bacterial diseases
0.853 0.147 0.000
D00-D09 In situ neoplasms
0.853 0.147 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.851 0.149 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.851 0.149 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.850 0.150 0.000
H61 Other disorders of external ear
0.844 0.156 0.000
Z29 Need for other prophylactic measures
0.840 0.160 0.000
H91 Other hearing loss
0.838 0.162 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.837 0.163 0.000
C78.2 Secondary malignant neoplasm of pleura
0.835 0.165 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.833 0.167 0.000
B15-B19 Viral hepatitis
0.830 0.170 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.829 0.171 0.000
O71 Other obstetric trauma
0.828 0.172 0.000
C51-C58 Malignant neoplasms of female genital organs
0.827 0.173 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.825 0.175 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.825 0.175 0.000
C50.9 Breast, unspecified
0.823 0.177 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.823 0.177 0.000
S80-S89 Injuries to the knee and lower leg
0.820 0.180 0.000
T42.4 Benzodiazepines
0.818 0.182 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.817 0.183 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.814 0.186 0.000
A41 Other septicaemia
0.814 0.186 0.000
M70-M79 Other soft tissue disorders
0.811 0.189 0.000
C16 Malignant neoplasm of stomach
0.810 0.190 0.000
Z40 Prophylactic surgery
0.809 0.191 0.000
H73 Other disorders of tympanic membrane
0.808 0.192 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.808 0.192 0.000
O70.9 Perineal laceration during delivery, unspecified
0.807 0.193 0.000
C20 Malignant neoplasm of rectum
0.805 0.194 0.000
Z45.1 Adjustment and management of infusion pump
0.805 0.195 0.000
Z04.5 Examination and observation following other inflicted injury
0.803 0.197 0.000
C17 Malignant neoplasm of small intestine
0.802 0.198 0.000
Z48.9 Surgical follow-up care, unspecified
0.802 0.198 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.802 0.198 0.000
H52.3 Anisometropia and aniseikonia
0.801 0.199 0.000
C18.9 Colon, unspecified
0.801 0.199 0.000
H74 Other disorders of middle ear and mastoid
0.800 0.200 0.000
O62 Abnormalities of forces of labour
0.799 0.201 0.000
C50.2 Upper-inner quadrant of breast
0.799 0.201 0.000
C77.2 Intra-abdominal lymph nodes
0.798 0.202 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.797 0.203 0.000
M25.5 Pain in joint
0.796 0.204 0.000
S50-S59 Injuries to the elbow and forearm
0.794 0.206 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.790 0.210 0.000
C77.0 Lymph nodes of head, face and neck
0.789 0.211 0.000
C77.1 Intrathoracic lymph nodes
0.788 0.212 0.000
B65-B83 Helminthiases
0.787 0.212 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.787 0.213 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.786 0.214 0.000
M86-M90 Other osteopathies
0.784 0.216 0.000
D45 Polycythaemia vera
0.783 0.217 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.783 0.217 0.000
S05 Injury of eye and orbit
0.782 0.218 0.000
O66 Other obstructed labour
0.781 0.219 0.000
M21 Other acquired deformities of limbs
0.781 0.219 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.779 0.221 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.779 0.221 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.778 0.222 0.000
H34 Retinal vascular occlusions
0.777 0.223 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.776 0.224 0.000
H52.2 Astigmatism
0.775 0.225 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.775 0.225 0.000
M24 Other specific joint derangements
0.774 0.226 0.000
C77.8 Lymph nodes of multiple regions
0.773 0.227 0.000
Chapter XX External causes of morbidity and mortality
0.773 0.227 0.000
H72 Perforation of tympanic membrane
0.772 0.228 0.000
O00-O08 Pregnancy with abortive outcome
0.771 0.229 0.000
C15.5 Lower third of oesophagus
0.767 0.233 0.000
M23.3 Other meniscus derangements
0.766 0.234 0.000
O80-O84 Delivery
0.764 0.236 0.000
Z04.3 Examination and observation following other accident
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.763 0.237 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.762 0.238 0.000
S01 Open wound of head
0.762 0.238 0.000
M23.8 Other internal derangements of knee
0.760 0.240 0.000
D46 Myelodysplastic syndromes
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.758 0.241 0.000
H91.9 Hearing loss, unspecified
0.757 0.243 0.000
S89 Other and unspecified injuries of lower leg
0.756 0.244 0.000
O85-O92 Complications predominantly related to the puerperium
0.755 0.245 0.000
C64-C68 Malignant neoplasms of urinary tract
0.755 0.245 0.000
Z44 Fitting and adjustment of external prosthetic device
0.754 0.246 0.000
A41.9 Septicaemia, unspecified
0.754 0.246 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.753 0.247 0.000
D69.5 Secondary thrombocytopenia
0.750 0.250 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.747 0.253 0.000
D03 Melanoma in situ
0.746 0.254 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.746 0.254 0.000
Z00.0 General medical examination
0.745 0.255 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.745 0.255 0.000
S00.1 Contusion of eyelid and periocular area
0.744 0.256 0.000
Z02 Examination and encounter for administrative purposes
0.743 0.257 0.000
Chapter VI Diseases of the nervous system
0.742 0.258 0.000
M33 Dermatopolymyositis
0.741 0.259 0.000
H92 Otalgia and effusion of ear
0.740 0.260 0.000
C56 Malignant neoplasm of ovary
0.737 0.263 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.737 0.263 0.000
O73 Retained placenta and membranes, without haemorrhage
0.736 0.264 0.000
Z54 Convalescence
0.734 0.266 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.733 0.267 0.000
M65 Synovitis and tenosynovitis
0.732 0.268 0.000
C22.1 Intrahepatic bile duct carcinoma
0.732 0.268 0.000
B99-B99 Other infectious diseases
0.731 0.269 0.000
M85 Other disorders of bone density and structure
0.731 0.269 0.000
H73.8 Other specified disorders of tympanic membrane
0.729 0.271 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.727 0.273 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.726 0.274 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.726 0.274 0.000
S06.5 Traumatic subdural haemorrhage
0.726 0.274 0.000
H93.1 Tinnitus
0.726 0.274 0.000
O61 Failed induction of labour
0.725 0.275 0.000
H33 Retinal detachments and breaks
0.725 0.275 0.000
Z29.2 Other prophylactic chemotherapy
0.725 0.275 0.000
S06.4 Epidural haemorrhage
0.724 0.276 0.000
M79.8 Other specified soft tissue disorders
0.724 0.276 0.000
Z29.0 Isolation
0.723 0.277 0.000
M25.8 Other specified joint disorders
0.722 0.278 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.722 0.278 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.721 0.279 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.720 0.280 0.000
Z34 Supervision of normal pregnancy
0.720 0.280 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.719 0.281 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.719 0.281 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.719 0.281 0.000
S00.0 Superficial injury of scalp
0.718 0.282 0.000
M25.56 Pain in joint (Lower leg)
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z48.8 Other specified surgical follow-up care
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
S01.8 Open wound of other parts of head
0.715 0.285 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.715 0.285 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.286 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.714 0.286 0.000
O60 Preterm delivery
0.714 0.286 0.000
H61.0 Perichondritis of external ear
0.714 0.286 0.000
O63 Long labour
0.714 0.286 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.713 0.286 0.000
C21 Malignant neoplasm of anus and anal canal
0.713 0.286 0.000
C23 Malignant neoplasm of gallbladder
0.713 0.286 0.000
B18 Chronic viral hepatitis
0.713 0.287 0.000
S89.9 Unspecified injury of lower leg
0.710 0.290 0.000
C16.0 Cardia
0.710 0.290 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.708 0.292 0.000
M25.7 Osteophyte
0.708 0.292 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.708 0.292 0.000
O71.8 Other specified obstetric trauma
0.707 0.293 0.000
Z43 Attention to artificial openings
0.706 0.294 0.000
H71 Cholesteatoma of middle ear
0.706 0.294 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.706 0.294 0.000
Z45.3 Adjustment and management of implanted hearing device
0.706 0.294 0.000
H40-H42 Glaucoma
0.705 0.295 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
Z12 Special screening examination for neoplasms
0.703 0.297 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.703 0.297 0.000
D70 Agranulocytosis
0.702 0.298 0.000
H52.0 Hypermetropia
0.702 0.298 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.701 0.299 0.000
A41.8 Other specified septicaemia
0.701 0.299 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.700 0.300 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.699 0.301 0.000
C22.9 Liver, unspecified
0.698 0.302 0.000
Z36 Antenatal screening
0.698 0.302 0.000
M25.9 Joint disorder, unspecified
0.697 0.303 0.000
C07 Malignant neoplasm of parotid gland
0.696 0.304 0.000
M25.0 Haemarthrosis
0.696 0.304 0.000
M67 Other disorders of synovium and tendon
0.695 0.305 0.000
S08 Traumatic amputation of part of head
0.695 0.305 0.000
S07 Crushing injury of head
0.695 0.305 0.000
S04 Injury of cranial nerves
0.695 0.305 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.695 0.305 0.000
D55-D59 Haemolytic anaemias
0.694 0.306 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.694 0.306 0.000
M31 Other necrotising vasculopathies
0.693 0.307 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.693 0.307 0.000
C79.2 Secondary malignant neoplasm of skin
0.692 0.308 0.000
C50.5 Lower-outer quadrant of breast
0.692 0.308 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.690 0.309 0.000
S90-S99 Injuries to the ankle and foot
0.690 0.310 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.690 0.310 0.000
H61.9 Disorder of external ear, unspecified
0.690 0.310 0.000
S60-S69 Injuries to the wrist and hand
0.690 0.310 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.690 0.310 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.690 0.310 0.000
S06.0 Concussion
0.689 0.310 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.689 0.311 0.000
D06 Carcinoma in situ of cervix uteri
0.688 0.312 0.000
H80-H83 Diseases of inner ear
0.688 0.312 0.000
O02 Other abnormal products of conception
0.688 0.312 0.000
L50-L54 Urticaria and erythema
0.688 0.312 0.000
M23.9 Internal derangement of knee, unspecified
0.687 0.313 0.000
D67 Hereditary factor IX deficiency
0.687 0.313 0.000
D66 Hereditary factor VIII deficiency
0.687 0.313 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.687 0.313 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.687 0.313 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.686 0.314 0.000
M34 Systemic sclerosis
0.686 0.314 0.000
M32 Systemic lupus erythematosus
0.686 0.314 0.000
M30 Polyarteritis nodosa and related conditions
0.686 0.314 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.686 0.314 0.000
H34.8 Other retinal vascular occlusions
0.686 0.314 0.000
O70.2 Third degree perineal laceration during delivery
0.685 0.315 0.000
Z51.9 Medical care, unspecified
0.685 0.315 0.000
H93.8 Other specified disorders of ear
0.685 0.315 0.000
H61.2 Impacted cerumen
0.684 0.316 0.000
D47.1 Chronic myeloproliferative disease
0.684 0.316 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.684 0.316 0.000
D69.9 Haemorrhagic condition, unspecified
0.683 0.317 0.000
D69.8 Other specified haemorrhagic conditions
0.683 0.317 0.000
D69.4 Other primary thrombocytopenia
0.683 0.317 0.000
D69.2 Other nonthrombocytopenic purpura
0.683 0.317 0.000
D69.1 Qualitative platelet defects
0.683 0.317 0.000
D69.0 Allergic purpura
0.683 0.317 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.683 0.317 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.682 0.318 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.682 0.318 0.000
Z04.9 Examination and observation for unspecified reason
0.681 0.319 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.681 0.319 0.000
O72 Postpartum haemorrhage
0.679 0.321 0.000
M00-M03 Infectious arthropathies
0.679 0.321 0.000
H36 Retinal disorders in diseases classified elsewhere
0.679 0.321 0.000
C10 Malignant neoplasm of oropharynx
0.679 0.321 0.000
M82 Osteoporosis in diseases classified elsewhere
0.679 0.321 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.679 0.321 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.678 0.322 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.678 0.322 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.678 0.322 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.678 0.322 0.000
Z57 Occupational exposure to risk-factors
0.678 0.322 0.000
B80 Enterobiasis
0.678 0.322 0.000
O70.3 Fourth degree perineal laceration during delivery
0.677 0.323 0.000
H60 Otitis externa
0.677 0.323 0.000
H33.0 Retinal detachment with retinal break
0.676 0.324 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.676 0.324 0.000
C18.6 Descending colon
0.675 0.324 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
S06.2 Diffuse brain injury
0.675 0.325 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.675 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.674 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.326 0.000
B50-B64 Protozoal diseases
0.674 0.326 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.674 0.326 0.000
A75-A79 Rickettsioses
0.674 0.326 0.000
A70-A74 Other diseases caused by chlamydiae
0.674 0.326 0.000
A65-A69 Other spirochaetal diseases
0.674 0.326 0.000
A20-A28 Certain zoonotic bacterial diseases
0.674 0.326 0.000
A15-A19 Tuberculosis
0.674 0.326 0.000
C77.4 Inguinal and lower limb lymph nodes
0.673 0.327 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.673 0.327 0.000
H31 Other disorders of choroid
0.673 0.327 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.673 0.327 0.000
S09 Other and unspecified injuries of head
0.673 0.327 0.000
Z51.0 Radiotherapy session
0.673 0.327 0.000
Z51.6 Desensitisation to allergens
0.672 0.327 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.672 0.328 0.000
H93.9 Disorder of ear, unspecified
0.672 0.328 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.672 0.328 0.000
Q60-Q64 Congenital malformations of the urinary system
0.672 0.328 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.671 0.329 0.000
C80 Malignant neoplasm without specification of site
0.671 0.329 0.000
T66-T78 Other and unspecified effects of external causes
0.669 0.330 0.000
C18.2 Ascending colon
0.670 0.330 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.669 0.331 0.000
M83 Adult osteomalacia
0.668 0.332 0.000
M25.3 Other instability of joint
0.668 0.332 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.668 0.332 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.667 0.333 0.000
C18.5 Splenic flexure
0.666 0.334 0.000
Z29.8 Other specified prophylactic measures
0.664 0.336 0.000
Z04.8 Examination and observation for other specified reasons
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.663 0.337 0.000
M25.50 Pain in joint (Multiple sites)
0.663 0.337 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
H10-H13 Disorders of conjunctiva
0.662 0.337 0.000
M21.0 Valgus deformity, not elsewhere classified
0.662 0.338 0.000
S20-S29 Injuries to the thorax
0.661 0.338 0.000
Y95 Nosocomial condition
0.661 0.339 0.000
Z10 Routine general health check-up of defined subpopulation
0.660 0.340 0.000
S00.5 Superficial injury of lip and oral cavity
0.660 0.340 0.000
S00.4 Superficial injury of ear
0.660 0.340 0.000
C18.4 Transverse colon
0.660 0.340 0.000
M81 Osteoporosis without pathological fracture
0.659 0.341 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.659 0.341 0.000
H70 Mastoiditis and related conditions
0.659 0.341 0.000
H68 Eustachian salpingitis and obstruction
0.659 0.341 0.000
H67 Otitis media in diseases classified elsewhere
0.659 0.341 0.000
C15.4 Middle third of oesophagus
0.659 0.341 0.000
H74.4 Polyp of middle ear
0.658 0.342 0.000
M79.1 Myalgia
0.657 0.343 0.000
Z47 Other orthopaedic follow-up care
0.657 0.343 0.000
H66 Suppurative and unspecified otitis media
0.656 0.344 0.000
M40-M43 Deforming dorsopathies
0.655 0.345 0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs
0.655 0.345 0.000
C15.9 Oesophagus, unspecified
0.654 0.346 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.654 0.346 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.654 0.346 0.000
M23.5 Chronic instability of knee
0.654 0.346 0.000
M23.1 Discoid meniscus (congenital)
0.654 0.346 0.000
M23.0 Cystic meniscus
0.654 0.346 0.000
Z00.4 General psychiatric examination, not elsewhere classified
0.654 0.346 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.653 0.347 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.653 0.347 0.000
H51 Other disorders of binocular movement
0.652 0.348 0.000
D68 Other coagulation defects
0.651 0.349 0.000
M71 Other bursopathies
0.651 0.349 0.000
S00.7 Multiple superficial injuries of head
0.650 0.350 0.000
M79.0 Rheumatism, unspecified
0.650 0.350 0.000
Z28 Immunisation not carried out
0.650 0.350 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.650 0.350 0.000
Z26 Need for immunisation against other single infectious diseases
0.650 0.350 0.000
Z25 Need for immunisation against other single viral diseases
0.650 0.350 0.000
Z24 Need for immunisation against certain single viral diseases
0.650 0.350 0.000
Z23 Need for immunisation against single bacterial diseases
0.650 0.350 0.000
Z20 Contact with and exposure to communicable diseases
0.650 0.350 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.650 0.350 0.000
S81 Open wound of lower leg
0.649 0.351 0.000
M80.8 Other osteoporosis with pathological fracture
0.648 0.352 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.648 0.352 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.648 0.352 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.648 0.352 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.648 0.352 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.648 0.352 0.000
S51 Open wound of forearm
0.648 0.352 0.000
B25-B34 Other viral diseases
0.647 0.353 0.000
Chapter V Mental and behavioural disorders
0.647 0.353 0.000
H74.0 Tympanosclerosis
0.647 0.353 0.000
M22 Disorders of patella
0.646 0.354 0.000
S50 Superficial injury of forearm
0.646 0.354 0.000
H52.7 Disorder of refraction, unspecified
0.646 0.354 0.000
H52.6 Other disorders of refraction
0.646 0.354 0.000
H52.5 Disorders of accommodation
0.646 0.354 0.000
H52.4 Presbyopia
0.646 0.354 0.000
S02 Fracture of skull and facial bones
0.646 0.354 0.000
D48.7 Other specified sites
0.645 0.355 0.000
G83 Other paralytic syndromes
0.645 0.355 0.000
D05 Carcinoma in situ of breast
0.644 0.356 0.000
L20-L30 Dermatitis and eczema
0.644 0.356 0.000
S06.8 Other intracranial injuries
0.643 0.357 0.000
C50.3 Lower-inner quadrant of breast
0.643 0.357 0.000
M25.54 Pain in joint (Hand)
0.643 0.357 0.000
S05.9 Injury of eye and orbit, part unspecified
0.642 0.358 0.000
M25.2 Flail joint
0.641 0.358 0.000
M25.1 Fistula of joint
0.641 0.358 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.641 0.359 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.641 0.359 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.641 0.359 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.641 0.359 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.641 0.359 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.641 0.359 0.000
T36 Poisoning by systemic antibiotics
0.641 0.359 0.000
M65.3 Trigger finger
0.641 0.359 0.000
T31 Burns classified according to extent of body surface involved
0.641 0.359 0.000
S01.3 Open wound of ear
0.640 0.360 0.000
B16 Acute hepatitis B
0.640 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.639 0.361 0.000
C79.6 Secondary malignant neoplasm of ovary
0.639 0.361 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.639 0.361 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.639 0.361 0.000
S06.9 Intracranial injury, unspecified
0.639 0.361 0.000
S06.7 Intracranial injury with prolonged coma
0.639 0.361 0.000
S06.3 Focal brain injury
0.639 0.361 0.000
S06.1 Traumatic cerebral oedema
0.639 0.361 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.637 0.363 0.000
C17.0 Duodenum
0.637 0.363 0.000
Z73 Problems related to life-management difficulty
0.637 0.363 0.000
D75 Other diseases of blood and blood-forming organs
0.636 0.364 0.000
T79-T79 Certain early complications of trauma
0.636 0.364 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.636 0.364 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.636 0.364 0.000
C78.7 Secondary malignant neoplasm of liver
0.635 0.365 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.635 0.365 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.634 0.366 0.000
O02.1 Missed abortion
0.634 0.366 0.000
H61.1 Non-infective disorders of pinna
0.633 0.367 0.000
Z04.6 General psychiatric examination, requested by authority
0.632 0.368 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.632 0.368 0.000
Z04.2 Examination and observation following work accident
0.632 0.368 0.000
Z04.0 Blood-alcohol and blood-drug test
0.632 0.368 0.000
B17 Other acute viral hepatitis
0.632 0.368 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.631 0.369 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.630 0.370 0.000
H92.1 Otorrhoea
0.629 0.371 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.629 0.371 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.629 0.371 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.629 0.371 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.629 0.371 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.629 0.371 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.629 0.371 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.629 0.371 0.000
C15.8 Overlapping lesion of oesophagus
0.628 0.372 0.000
C15.3 Upper third of oesophagus
0.628 0.372 0.000
C15.2 Abdominal part of oesophagus
0.628 0.372 0.000
C15.1 Thoracic part of oesophagus
0.628 0.372 0.000
C15.0 Cervical part of oesophagus
0.628 0.372 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.627 0.373 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.626 0.374 0.000
H30 Chorioretinal inflammation
0.626 0.374 0.000
C18.8 Overlapping lesion of colon
0.626 0.374 0.000
C18.1 Appendix
0.626 0.374 0.000
C50.6 Axillary tail of breast
0.625 0.375 0.000
C50.0 Nipple and areola
0.625 0.375 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.625 0.375 0.000
B95-B98 Bacterial, viral and other infectious agents
0.625 0.375 0.000
M05-M14 Inflammatory polyarthropathies
0.624 0.376 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.624 0.376 0.000
Z60 Problems related to social environment
0.623 0.376 0.000
H72.2 Other marginal perforations of tympanic membrane
0.623 0.377 0.000
C01 Malignant neoplasm of base of tongue
0.623 0.377 0.000
D46.2 Refractory anaemia with excess of blasts
0.622 0.378 0.000
O62.0 Primary inadequate contractions
0.622 0.378 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.622 0.378 0.000
C22.7 Other specified carcinomas of liver
0.621 0.379 0.000
C22.4 Other sarcomas of liver
0.621 0.379 0.000
C22.3 Angiosarcoma of liver
0.621 0.379 0.000
C22.2 Hepatoblastoma
0.621 0.379 0.000
C22.0 Liver cell carcinoma
0.621 0.379 0.000
Z52 Donors of organs and tissues
0.620 0.380 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.620 0.380 0.000
C25 Malignant neoplasm of pancreas
0.620 0.380 0.000
Q80-Q89 Other congenital malformations
0.620 0.380 0.000
C09 Malignant neoplasm of tonsil
0.619 0.381 0.000
Q00-Q07 Congenital malformations of the nervous system
0.619 0.381 0.000
Z32 Pregnancy examination and test
0.618 0.382 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.618 0.382 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.618 0.382 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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