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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74635668
log Bayes Factor = 12.4172
Chromosome 14   position 54,188,200  (GRCh37) Explore rs74635668 on Ensembl!
Variant rs74635668 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
R10 Abdominal and pelvic pain
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
B95-B98 Bacterial, viral and other infectious agents
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
Chapter II Neoplasms
0.982 0.018 0.000
E10-E14 Diabetes mellitus
0.982 0.018 0.000
R11 Nausea and vomiting
0.974 0.026 0.000
F30-F39 Mood [affective] disorders
0.974 0.026 0.000
E10 Insulin-dependent diabetes mellitus
0.973 0.027 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
T81 Complications of procedures, not elsewhere classified
0.968 0.032 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.968 0.032 0.000
M50-M54 Other dorsopathies
0.968 0.032 0.000
R10.3 Pain localised to other parts of lower abdomen
0.966 0.034 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.962 0.038 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
C15-C26 Malignant neoplasms of digestive organs
0.961 0.039 0.000
Chapter IX Diseases of the circulatory system
0.959 0.041 0.000
I73 Other peripheral vascular diseases
0.959 0.041 0.000
I73.0 Raynaud's syndrome
0.955 0.045 0.000
R50-R69 General symptoms and signs
0.951 0.049 0.000
R10.1 Pain localised to upper abdomen
0.949 0.051 0.000
R60 Oedema, not elsewhere classified
0.948 0.052 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.946 0.054 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.942 0.058 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.941 0.059 0.000
R60.0 Localised oedema
0.941 0.059 0.000
E10.4 With neurological complications
0.932 0.068 0.000
M54 Dorsalgia
0.929 0.071 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.926 0.074 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.923 0.077 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.922 0.078 0.000
C15 Malignant neoplasm of oesophagus
0.914 0.086 0.000
T66-T78 Other and unspecified effects of external causes
0.913 0.087 0.000
I77 Other disorders of arteries and arterioles
0.913 0.087 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.910 0.090 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.909 0.091 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.909 0.091 0.000
Chapter VI Diseases of the nervous system
0.907 0.093 0.000
F32 Depressive episode
0.907 0.093 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.902 0.098 0.000
E11 Non-insulin-dependent diabetes mellitus
0.899 0.101 0.000
M45-M49 Spondylopathies
0.899 0.101 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.892 0.108 0.000
D69 Purpura and other haemorrhagic conditions
0.892 0.108 0.000
C16 Malignant neoplasm of stomach
0.890 0.110 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.890 0.110 0.000
R18 Ascites
0.890 0.110 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.886 0.114 0.000
Chapter VIII Diseases of the ear and mastoid process
0.883 0.117 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.881 0.119 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.880 0.120 0.000
A30-A49 Other bacterial diseases
0.875 0.125 0.000
M54.5 Low back pain
0.874 0.126 0.000
F33 Recurrent depressive disorder
0.873 0.127 0.000
R60.9 Oedema, unspecified
0.870 0.130 0.000
I77.1 Stricture of artery
0.866 0.134 0.000
W00-W19 Falls
0.863 0.137 0.000
T51 Toxic effect of alcohol
0.861 0.139 0.000
R05 Cough
0.854 0.146 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.853 0.147 0.000
R10.0 Acute abdomen
0.851 0.148 0.000
F32.9 Depressive episode, unspecified
0.847 0.153 0.000
R52 Pain, not elsewhere classified
0.847 0.153 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.845 0.155 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.844 0.156 0.000
F31 Bipolar affective disorder
0.843 0.157 0.000
E10.3 With ophthalmic complications
0.843 0.157 0.000
H65-H75 Diseases of middle ear and mastoid
0.840 0.160 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.839 0.161 0.000
R06 Abnormalities of breathing
0.839 0.161 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.835 0.165 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.834 0.166 0.000
T78 Adverse effects, not elsewhere classified
0.833 0.167 0.000
C16.0 Cardia
0.831 0.169 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.831 0.169 0.000
R02 Gangrene, not elsewhere classified
0.829 0.171 0.000
E10.9 Without complications
0.828 0.172 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.828 0.172 0.000
D69.6 Thrombocytopenia, unspecified
0.827 0.173 0.000
R12 Heartburn
0.827 0.173 0.000
M51 Other intervertebral disk disorders
0.826 0.174 0.000
C15.5 Lower third of oesophagus
0.825 0.175 0.000
Chapter XXI Factors influencing health status and contact with health services
0.823 0.177 0.000
G90-G99 Other disorders of the nervous system
0.823 0.177 0.000
C64-C68 Malignant neoplasms of urinary tract
0.823 0.177 0.000
S20-S29 Injuries to the thorax
0.820 0.180 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.817 0.183 0.000
C15.9 Oesophagus, unspecified
0.816 0.184 0.000
O20 Haemorrhage in early pregnancy
0.815 0.185 0.000
Chapter XXII Codes for special purposes
0.811 0.189 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.810 0.190 0.000
E11.3 With ophthalmic complications
0.808 0.192 0.000
I73.9 Peripheral vascular disease, unspecified
0.806 0.194 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.805 0.195 0.000
Z36 Antenatal screening
0.805 0.195 0.000
M80-M85 Disorders of bone density and structure
0.801 0.199 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.799 0.201 0.000
O26.9 Pregnancy-related condition, unspecified
0.798 0.202 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.796 0.204 0.000
I74 Arterial embolism and thrombosis
0.795 0.205 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.793 0.207 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.792 0.208 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.790 0.210 0.000
M20-M25 Other joint disorders
0.789 0.211 0.000
T86 Failure and rejection of transplanted organs and tissues
0.788 0.212 0.000
S80-S89 Injuries to the knee and lower leg
0.788 0.212 0.000
M54.9 Dorsalgia, unspecified
0.787 0.213 0.000
A41 Other septicaemia
0.786 0.214 0.000
E65-E68 Obesity and other hyperalimentation
0.786 0.214 0.000
T51.0 Ethanol
0.786 0.214 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.784 0.216 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.783 0.217 0.000
H72 Perforation of tympanic membrane
0.780 0.220 0.000
G20-G26 Extrapyramidal and movement disorders
0.780 0.220 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.780 0.220 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.780 0.220 0.000
E10.5 With peripheral circulatory complications
0.778 0.222 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.778 0.222 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.776 0.223 0.000
Z36.9 Antenatal screening, unspecified
0.776 0.224 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.775 0.225 0.000
C51-C58 Malignant neoplasms of female genital organs
0.775 0.225 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.774 0.226 0.000
C25 Malignant neoplasm of pancreas
0.773 0.227 0.000
R56 Convulsions, not elsewhere classified
0.772 0.228 0.000
X10-X19 Contact with heat and hot substances
0.771 0.229 0.000
B35-B49 Mycoses
0.770 0.230 0.000
F32.0 Mild depressive episode
0.769 0.231 0.000
R17 Unspecified jaundice
0.769 0.231 0.000
R09.1 Pleurisy
0.766 0.234 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.766 0.234 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.766 0.234 0.000
M48 Other spondylopathies
0.764 0.236 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.763 0.237 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.762 0.238 0.000
D50-D53 Nutritional anaemias
0.761 0.239 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.760 0.240 0.000
R52.2 Other chronic pain
0.759 0.241 0.000
E10.2 With renal complications
0.757 0.243 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.756 0.244 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.756 0.244 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.756 0.244 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.755 0.244 0.000
M50 Cervical disk disorders
0.755 0.245 0.000
E14 Unspecified diabetes mellitus
0.754 0.246 0.000
O16 Unspecified maternal hypertension
0.752 0.248 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.752 0.248 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.751 0.249 0.000
W19 Unspecified fall
0.751 0.249 0.000
M54.56 Low back pain (Lumbar region)
0.750 0.250 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.748 0.252 0.000
Z22 Carrier of infectious disease
0.748 0.252 0.000
R14 Flatulence and related conditions
0.747 0.253 0.000
D70 Agranulocytosis
0.747 0.253 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.255 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.744 0.256 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.743 0.257 0.000
Z34 Supervision of normal pregnancy
0.741 0.259 0.000
E11.2 With renal complications
0.740 0.260 0.000
E40-E46 Malnutrition
0.739 0.260 0.000
E11.4 With neurological complications
0.739 0.260 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.739 0.261 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.739 0.261 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.739 0.261 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.739 0.261 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.739 0.261 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.738 0.262 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.737 0.263 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.736 0.264 0.000
M54.4 Lumbago with sciatica
0.735 0.265 0.000
S10-S19 Injuries to the neck
0.733 0.267 0.000
E50-E64 Other nutritional deficiencies
0.731 0.269 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.730 0.270 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.730 0.270 0.000
C67 Malignant neoplasm of bladder
0.730 0.270 0.000
M45 Ankylosing spondylitis
0.729 0.271 0.000
I27 Other pulmonary heart diseases
0.728 0.272 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.727 0.273 0.000
T78.3 Angioneurotic oedema
0.727 0.273 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.727 0.273 0.000
Chapter XIV Diseases of the genitourinary system
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.274 0.000
X60-X84 Intentional self-harm
0.725 0.275 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.725 0.275 0.000
T78.4 Allergy, unspecified
0.725 0.275 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
C18 Malignant neoplasm of colon
0.721 0.279 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.721 0.279 0.000
O20.0 Threatened abortion
0.721 0.279 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.718 0.282 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.717 0.283 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.716 0.284 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.716 0.284 0.000
R57 Shock, not elsewhere classified
0.715 0.285 0.000
T59 Toxic effect of other gases, fumes and vapours
0.714 0.286 0.000
R06.8 Other and unspecified abnormalities of breathing
0.714 0.286 0.000
T68 Hypothermia
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.287 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.711 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.711 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.288 0.000
B65-B83 Helminthiases
0.711 0.288 0.000
B50-B64 Protozoal diseases
0.711 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.288 0.000
A75-A79 Rickettsioses
0.711 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.288 0.000
A65-A69 Other spirochaetal diseases
0.711 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.288 0.000
A15-A19 Tuberculosis
0.711 0.288 0.000
B15-B19 Viral hepatitis
0.711 0.289 0.000
M47 Spondylosis
0.710 0.290 0.000
T51.9 Alcohol, unspecified
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F80-F89 Disorders of psychological development
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
Y83.4 Other reconstructive surgery
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
M54.57 Low back pain (Lumbosacral region)
0.709 0.291 0.000
V10-V19 Pedal cyclist injured in transport accident
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
D55-D59 Haemolytic anaemias
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.293 0.000
G95 Other diseases of spinal cord
0.707 0.293 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.706 0.294 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.704 0.296 0.000
I72 Other aneurysm
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.296 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
A00-A09 Intestinal infectious diseases
0.702 0.298 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.702 0.298 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.701 0.299 0.000
Z22.3 Carrier of other specified bacterial diseases
0.700 0.299 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.700 0.300 0.000
Z33 Pregnant state, incidental
0.700 0.300 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.699 0.301 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.699 0.301 0.000
F38 Other mood [affective] disorders
0.698 0.302 0.000
F34 Persistent mood [affective] disorders
0.698 0.302 0.000
F30 Manic episode
0.698 0.302 0.000
F39 Unspecified mood [affective] disorder
0.698 0.302 0.000
C54 Malignant neoplasm of corpus uteri
0.698 0.302 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.698 0.302 0.000
E10.8 With unspecified complications
0.698 0.302 0.000
E10.7 With multiple complications
0.698 0.302 0.000
E10.6 With other specified complications
0.698 0.302 0.000
E10.0 With coma
0.698 0.302 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.697 0.303 0.000
M54.1 Radiculopathy
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
F31.9 Bipolar affective disorder, unspecified
0.696 0.304 0.000
C92 Myeloid leukaemia
0.695 0.305 0.000
E13 Other specified diabetes mellitus
0.695 0.305 0.000
T81.9 Unspecified complication of procedure
0.694 0.306 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.694 0.306 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.694 0.306 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.694 0.306 0.000
R54 Senility
0.694 0.306 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.694 0.306 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.694 0.306 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.694 0.306 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.694 0.306 0.000
M53 Other dorsopathies, not elsewhere classified
0.694 0.306 0.000
R04 Haemorrhage from respiratory passages
0.694 0.306 0.000
O60-O75 Complications of labour and delivery
0.694 0.306 0.000
I77.6 Arteritis, unspecified
0.694 0.306 0.000
H74 Other disorders of middle ear and mastoid
0.693 0.307 0.000
M54.2 Cervicalgia
0.692 0.307 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.692 0.308 0.000
M70-M79 Other soft tissue disorders
0.692 0.308 0.000
W07 Fall involving chair
0.691 0.309 0.000
H73 Other disorders of tympanic membrane
0.691 0.309 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.690 0.310 0.000
R47-R49 Symptoms and signs involving speech and voice
0.690 0.310 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.690 0.310 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.689 0.311 0.000
D46 Myelodysplastic syndromes
0.689 0.311 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.689 0.311 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.689 0.311 0.000
C21 Malignant neoplasm of anus and anal canal
0.689 0.311 0.000
C17 Malignant neoplasm of small intestine
0.689 0.311 0.000
C23 Malignant neoplasm of gallbladder
0.689 0.311 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.689 0.311 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.688 0.312 0.000
I00-I02 Acute rheumatic fever
0.688 0.312 0.000
I73.8 Other specified peripheral vascular diseases
0.687 0.313 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.687 0.313 0.000
N40-N51 Diseases of male genital organs
0.687 0.313 0.000
S90-S99 Injuries to the ankle and foot
0.687 0.313 0.000
R06.2 Wheezing
0.687 0.313 0.000
I70 Atherosclerosis
0.686 0.313 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.686 0.314 0.000
D68 Other coagulation defects
0.685 0.315 0.000
E14.3 With ophthalmic complications
0.685 0.315 0.000
F43 Reaction to severe stress, and adjustment disorders
0.685 0.315 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.685 0.315 0.000
S50-S59 Injuries to the elbow and forearm
0.685 0.315 0.000
M84 Disorders of continuity of bone
0.684 0.315 0.000
M50.3 Other cervical disk degeneration
0.684 0.316 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.684 0.316 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.684 0.316 0.000
E11.5 With peripheral circulatory complications
0.683 0.317 0.000
D10-D36 Benign neoplasms
0.683 0.317 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.682 0.318 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.682 0.318 0.000
R62 Lack of expected normal physiological development
0.682 0.318 0.000
R64 Cachexia
0.682 0.318 0.000
R58 Haemorrhage, not elsewhere classified
0.682 0.318 0.000
M24 Other specific joint derangements
0.681 0.319 0.000
G30-G32 Other degenerative diseases of the nervous system
0.680 0.320 0.000
R60.1 Generalised oedema
0.680 0.320 0.000
R06.1 Stridor
0.680 0.320 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.680 0.320 0.000
G20 Parkinson's disease
0.679 0.321 0.000
Z36.8 Other antenatal screening
0.679 0.321 0.000
O85-O92 Complications predominantly related to the puerperium
0.678 0.322 0.000
M54.6 Pain in thoracic spine
0.678 0.322 0.000
C16.9 Stomach, unspecified
0.677 0.323 0.000
E10.1 With ketoacidosis
0.677 0.323 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.675 0.325 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.675 0.325 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.675 0.325 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.674 0.326 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.674 0.326 0.000
Y40 Systemic antibiotics
0.673 0.327 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.672 0.327 0.000
R06.0 Dyspnoea
0.671 0.329 0.000
C85.1 B-cell lymphoma, unspecified
0.670 0.330 0.000
M20 Acquired deformities of fingers and toes
0.669 0.331 0.000
M40-M43 Deforming dorsopathies
0.668 0.332 0.000
M65-M68 Disorders of synovium and tendon
0.668 0.332 0.000
C18.9 Colon, unspecified
0.667 0.332 0.000
M48.0 Spinal stenosis
0.667 0.333 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.666 0.334 0.000
S40 Superficial injury of shoulder and upper arm
0.666 0.334 0.000
M54.8 Other dorsalgia
0.666 0.334 0.000
M54.0 Panniculitis affecting regions of neck and back
0.666 0.334 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.665 0.335 0.000
E11.1 With ketoacidosis
0.665 0.335 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.664 0.336 0.000
M51.2 Other specified intervertebral disk displacement
0.664 0.336 0.000
T65 Toxic effect of other and unspecified substances
0.664 0.336 0.000
T63 Toxic effect of contact with venomous animals
0.664 0.336 0.000
T62 Toxic effect of other noxious substances eaten as food
0.664 0.336 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.664 0.336 0.000
T60 Toxic effect of pesticides
0.664 0.336 0.000
T57 Toxic effect of other inorganic substances
0.664 0.336 0.000
T56 Toxic effect of metals
0.664 0.336 0.000
T54 Toxic effect of corrosive substances
0.664 0.336 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.664 0.336 0.000
T52 Toxic effect of organic solvents
0.664 0.336 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.664 0.336 0.000
T58 Toxic effect of carbon monoxide
0.664 0.336 0.000
T55 Toxic effect of soaps and detergents
0.664 0.336 0.000
Z34.8 Supervision of other normal pregnancy
0.664 0.336 0.000
R10.2 Pelvic and perineal pain
0.664 0.336 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.663 0.337 0.000
S60-S69 Injuries to the wrist and hand
0.663 0.337 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.662 0.338 0.000
W19.9 Unspecified place
0.662 0.338 0.000
S20 Superficial injury of thorax
0.662 0.338 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
D67 Hereditary factor IX deficiency
0.661 0.338 0.000
D66 Hereditary factor VIII deficiency
0.661 0.338 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.661 0.338 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.661 0.339 0.000
R52.1 Chronic intractable pain
0.660 0.340 0.000
Q60-Q64 Congenital malformations of the urinary system
0.660 0.340 0.000
M54.59 Low back pain (Site unspecified)
0.659 0.341 0.000
O23 Infections of genito-urinary tract in pregnancy
0.658 0.342 0.000
W06 Fall involving bed
0.657 0.343 0.000
I78 Diseases of capillaries
0.657 0.343 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.656 0.344 0.000
C15.8 Overlapping lesion of oesophagus
0.655 0.345 0.000
C15.4 Middle third of oesophagus
0.655 0.345 0.000
C15.3 Upper third of oesophagus
0.655 0.345 0.000
C15.2 Abdominal part of oesophagus
0.655 0.345 0.000
C15.1 Thoracic part of oesophagus
0.655 0.345 0.000
C15.0 Cervical part of oesophagus
0.655 0.345 0.000
M21 Other acquired deformities of limbs
0.655 0.345 0.000
T75 Effects of other external causes
0.655 0.345 0.000
T74 Maltreatment syndromes
0.655 0.345 0.000
T73 Effects of other deprivation
0.655 0.345 0.000
T70 Effects of air pressure and water pressure
0.655 0.345 0.000
T69 Other effects of reduced temperature
0.655 0.345 0.000
T67 Effects of heat and light
0.655 0.345 0.000
T71 Asphyxiation
0.655 0.345 0.000
T66 Unspecified effects of radiation
0.655 0.345 0.000
I77.8 Other specified disorders of arteries and arterioles
0.654 0.345 0.000
I77.5 Necrosis of artery
0.654 0.345 0.000
I77.4 Coeliac artery compression syndrome
0.654 0.345 0.000
I77.3 Arterial fibromuscular dysplasia
0.654 0.345 0.000
I77.2 Rupture of artery
0.654 0.345 0.000
I77.0 Arteriovenous fistula, acquired
0.654 0.345 0.000
Z22.5 Carrier of viral hepatitis
0.654 0.346 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.653 0.347 0.000
O80-O84 Delivery
0.653 0.347 0.000
A46 Erysipelas
0.653 0.347 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.652 0.348 0.000
M46 Other inflammatory spondylopathies
0.652 0.348 0.000
S81 Open wound of lower leg
0.652 0.348 0.000
O29 Complications of anaesthesia during pregnancy
0.652 0.348 0.000
O28 Abnormal findings on antenatal screening of mother
0.652 0.348 0.000
O24 Diabetes mellitus in pregnancy
0.652 0.348 0.000
O22 Venous complications in pregnancy
0.652 0.348 0.000
O21 Excessive vomiting in pregnancy
0.652 0.348 0.000
O25 Malnutrition in pregnancy
0.652 0.348 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.652 0.348 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.652 0.348 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.652 0.348 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.652 0.348 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.651 0.349 0.000
V20-V29 Motorcycle rider injured in transport accident
0.650 0.350 0.000
F32.8 Other depressive episodes
0.650 0.350 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.650 0.350 0.000
N17-N19 Renal failure
0.649 0.351 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.649 0.351 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.648 0.352 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.646 0.354 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.645 0.355 0.000
E11.8 With unspecified complications
0.645 0.355 0.000
E11.7 With multiple complications
0.645 0.355 0.000
E11.6 With other specified complications
0.645 0.355 0.000
E11.0 With coma
0.645 0.355 0.000
M49 Spondylopathies in diseases classified elsewhere
0.645 0.355 0.000
R56.8 Other and unspecified convulsions
0.644 0.356 0.000
G70-G73 Diseases of myoneural junction and muscle
0.644 0.356 0.000
C54.1 Endometrium
0.643 0.357 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.642 0.357 0.000
R68 Other general symptoms and signs
0.642 0.358 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.642 0.358 0.000
N48 Other disorders of penis
0.641 0.359 0.000
I27.2 Other secondary pulmonary hypertension
0.640 0.360 0.000
D69.9 Haemorrhagic condition, unspecified
0.639 0.361 0.000
D69.8 Other specified haemorrhagic conditions
0.639 0.361 0.000
D69.5 Secondary thrombocytopenia
0.639 0.361 0.000
D69.4 Other primary thrombocytopenia
0.639 0.361 0.000
D69.2 Other nonthrombocytopenic purpura
0.639 0.361 0.000
D69.1 Qualitative platelet defects
0.639 0.361 0.000
D69.0 Allergic purpura
0.639 0.361 0.000
R63 Symptoms and signs concerning food and fluid intake
0.639 0.361 0.000
C16.8 Overlapping lesion of stomach
0.638 0.361 0.000
C16.6 Greater curvature of stomach, unspecified
0.638 0.361 0.000
C16.5 Lesser curvature of stomach, unspecified
0.638 0.361 0.000
C16.4 Pylorus
0.638 0.361 0.000
C16.3 Pyloric antrum
0.638 0.361 0.000
C16.2 Body of stomach
0.638 0.361 0.000
C16.1 Fundus of stomach
0.638 0.361 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.638 0.362 0.000
W20-W49 Exposure to inanimate mechanical forces
0.638 0.362 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.638 0.362 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.637 0.363 0.000
E20-E35 Disorders of other endocrine glands
0.637 0.363 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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