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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74648291
log Bayes Factor = 8.7
Chromosome 5   position 176,165,781  (GRCh37) Explore rs74648291 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
E20-E35 Disorders of other endocrine glands
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
S00-S09 Injuries to the head
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.988 0.012 0.000
E70-E90 Metabolic disorders
0.977 0.023 0.000
S09 Other and unspecified injuries of head
0.975 0.025 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.973 0.027 0.000
M45-M49 Spondylopathies
0.961 0.039 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.959 0.041 0.000
Chapter V Mental and behavioural disorders
0.957 0.043 0.000
S09.9 Unspecified injury of head
0.956 0.044 0.000
E87.2 Acidosis
0.955 0.045 0.000
S02 Fracture of skull and facial bones
0.950 0.050 0.000
G62 Other polyneuropathies
0.940 0.060 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.935 0.065 0.000
S20-S29 Injuries to the thorax
0.924 0.076 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.922 0.078 0.000
Chapter II Neoplasms
0.921 0.079 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.916 0.084 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.916 0.084 0.000
M50-M54 Other dorsopathies
0.916 0.084 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.915 0.085 0.000
M48 Other spondylopathies
0.908 0.092 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.906 0.094 0.000
G62.9 Polyneuropathy, unspecified
0.905 0.095 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.904 0.096 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.902 0.098 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.900 0.100 0.000
M80-M85 Disorders of bone density and structure
0.898 0.102 0.000
S10-S19 Injuries to the neck
0.895 0.105 0.000
W20-W49 Exposure to inanimate mechanical forces
0.895 0.105 0.000
E27 Other disorders of adrenal gland
0.894 0.106 0.000
G90-G99 Other disorders of the nervous system
0.894 0.106 0.000
S80-S89 Injuries to the knee and lower leg
0.891 0.109 0.000
S40-S49 Injuries to the shoulder and upper arm
0.888 0.112 0.000
E87.5 Hyperkalaemia
0.887 0.113 0.000
Chapter VII Diseases of the eye and adnexa
0.886 0.114 0.000
M51 Other intervertebral disk disorders
0.885 0.115 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.885 0.115 0.000
M91-M94 Chondropathies
0.883 0.117 0.000
E21.0 Primary hyperparathyroidism
0.878 0.122 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.875 0.125 0.000
Chapter I Certain infectious and parasitic diseases
0.874 0.126 0.000
E87.6 Hypokalaemia
0.874 0.126 0.000
E28 Ovarian dysfunction
0.872 0.128 0.000
E86 Volume depletion
0.869 0.131 0.000
G30-G32 Other degenerative diseases of the nervous system
0.866 0.134 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.860 0.140 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.858 0.142 0.000
G20-G26 Extrapyramidal and movement disorders
0.858 0.142 0.000
M65-M68 Disorders of synovium and tendon
0.858 0.142 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.857 0.142 0.000
E50-E64 Other nutritional deficiencies
0.857 0.143 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.855 0.145 0.000
A30-A49 Other bacterial diseases
0.853 0.147 0.000
E40-E46 Malnutrition
0.851 0.149 0.000
C85.1 B-cell lymphoma, unspecified
0.850 0.150 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.850 0.150 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.850 0.150 0.000
G62.8 Other specified polyneuropathies
0.843 0.157 0.000
A41 Other septicaemia
0.841 0.159 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.840 0.160 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.836 0.164 0.000
D00-D09 In situ neoplasms
0.836 0.164 0.000
M60-M63 Disorders of muscles
0.835 0.165 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.834 0.166 0.000
M48.0 Spinal stenosis
0.830 0.170 0.000
M47 Spondylosis
0.828 0.172 0.000
M46 Other inflammatory spondylopathies
0.827 0.173 0.000
S06 Intracranial injury
0.825 0.175 0.000
W00-W19 Falls
0.824 0.176 0.000
S02.4 Fracture of malar and maxillary bones
0.821 0.179 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.821 0.179 0.000
T79-T79 Certain early complications of trauma
0.817 0.183 0.000
E87.7 Fluid overload
0.816 0.184 0.000
M86-M90 Other osteopathies
0.816 0.184 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.816 0.184 0.000
S09.8 Other specified injuries of head
0.815 0.185 0.000
D05 Carcinoma in situ of breast
0.815 0.185 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.815 0.185 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.814 0.186 0.000
Y00-Y09 Assault
0.812 0.187 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.812 0.188 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.811 0.189 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.810 0.190 0.000
F60-F69 Disorders of adult personality and behaviour
0.810 0.190 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.808 0.192 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.808 0.192 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.808 0.192 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.807 0.193 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.805 0.195 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.804 0.196 0.000
S02.3 Fracture of orbital floor
0.802 0.198 0.000
F20 Schizophrenia
0.802 0.198 0.000
Q80-Q89 Other congenital malformations
0.802 0.198 0.000
S42 Fracture of shoulder and upper arm
0.800 0.200 0.000
S27 Injury of other and unspecified intrathoracic organs
0.798 0.202 0.000
V80-V89 Other land transport accidents
0.798 0.202 0.000
T14 Injury of unspecified body region
0.797 0.202 0.000
M65 Synovitis and tenosynovitis
0.797 0.203 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.797 0.203 0.000
W50-W64 Exposure to animate mechanical forces
0.797 0.203 0.000
S82 Fracture of lower leg, including ankle
0.797 0.203 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
S02.0 Fracture of vault of skull
0.794 0.206 0.000
H30-H36 Disorders of choroid and retina
0.792 0.208 0.000
M84 Disorders of continuity of bone
0.790 0.210 0.000
G96 Other disorders of central nervous system
0.787 0.213 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.785 0.215 0.000
S02.1 Fracture of base of skull
0.785 0.215 0.000
W75-W84 Other accidental threats to breathing
0.784 0.216 0.000
M51.2 Other specified intervertebral disk displacement
0.783 0.217 0.000
W25 Contact with sharp glass
0.781 0.219 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.780 0.220 0.000
M94 Other disorders of cartilage
0.776 0.224 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.776 0.224 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.772 0.228 0.000
S02.6 Fracture of mandible
0.771 0.229 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.770 0.230 0.000
V40-V49 Car occupant injured in transport accident
0.769 0.231 0.000
E28.2 Polycystic ovarian syndrome
0.767 0.233 0.000
E27.2 Addisonian crisis
0.766 0.234 0.000
H43-H45 Disorders of vitreous body and globe
0.765 0.235 0.000
E53 Deficiency of other B group vitamins
0.764 0.236 0.000
E29 Testicular dysfunction
0.764 0.236 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.764 0.236 0.000
S50-S59 Injuries to the elbow and forearm
0.763 0.237 0.000
C45 Mesothelioma
0.759 0.241 0.000
M47.2 Other spondylosis with radiculopathy
0.758 0.242 0.000
E22 Hyperfunction of pituitary gland
0.758 0.242 0.000
G20 Parkinson's disease
0.757 0.243 0.000
T90 Sequelae of injuries of head
0.754 0.246 0.000
F30-F39 Mood [affective] disorders
0.754 0.246 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.754 0.246 0.000
A41.9 Septicaemia, unspecified
0.753 0.247 0.000
Y40 Systemic antibiotics
0.752 0.248 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.751 0.249 0.000
T59 Toxic effect of other gases, fumes and vapours
0.749 0.251 0.000
W29 Contact with other powered hand tools and household machinery
0.748 0.251 0.000
E87.3 Alkalosis
0.748 0.252 0.000
E24 Cushing's syndrome
0.748 0.252 0.000
S12 Fracture of neck
0.747 0.252 0.000
F80-F89 Disorders of psychological development
0.747 0.253 0.000
F01 Vascular dementia
0.747 0.253 0.000
M48.02 Spinal stenosis (Cervical region)
0.747 0.253 0.000
E46 Unspecified protein-energy malnutrition
0.745 0.255 0.000
G12 Spinal muscular atrophy and related syndromes
0.745 0.255 0.000
E27.1 Primary adrenocortical insufficiency
0.745 0.255 0.000
T00-T07 Injuries involving multiple body regions
0.745 0.255 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.745 0.255 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.743 0.257 0.000
Q00-Q07 Congenital malformations of the nervous system
0.742 0.258 0.000
Y42.7 Androgens and anabolic congeners
0.742 0.258 0.000
S29 Other and unspecified injuries of thorax
0.741 0.259 0.000
E26 Hyperaldosteronism
0.739 0.261 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.739 0.261 0.000
V10-V19 Pedal cyclist injured in transport accident
0.738 0.262 0.000
F20.9 Schizophrenia, unspecified
0.738 0.262 0.000
T09 Other injuries of spine and trunk, level unspecified
0.738 0.262 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.737 0.263 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.737 0.263 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.735 0.265 0.000
X10-X19 Contact with heat and hot substances
0.734 0.266 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.733 0.267 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.732 0.268 0.000
Y44 Agents primarily affecting blood constituents
0.732 0.268 0.000
C91 Lymphoid leukaemia
0.730 0.270 0.000
G51 Facial nerve disorders
0.730 0.270 0.000
G83 Other paralytic syndromes
0.730 0.270 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.730 0.270 0.000
E23 Hypofunction and other disorders of pituitary gland
0.729 0.271 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.728 0.272 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.728 0.272 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.728 0.272 0.000
T92 Sequelae of injuries of upper limb
0.728 0.272 0.000
S42.2 Fracture of upper end of humerus
0.727 0.272 0.000
C34 Malignant neoplasm of bronchus and lung
0.727 0.273 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.727 0.273 0.000
M62 Other disorders of muscle
0.725 0.275 0.000
S41 Open wound of shoulder and upper arm
0.725 0.275 0.000
F22 Persistent delusional disorders
0.723 0.277 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.722 0.278 0.000
S21 Open wound of thorax
0.722 0.278 0.000
X20-X29 Contact with venomous animals and plants
0.720 0.280 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.720 0.280 0.000
H04 Disorders of lachrymal system
0.719 0.281 0.000
F29 Unspecified nonorganic psychosis
0.719 0.281 0.000
G61 Inflammatory polyneuropathy
0.719 0.281 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.718 0.282 0.000
E85 Amyloidosis
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
G54 Nerve root and plexus disorders
0.715 0.285 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.715 0.285 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.714 0.285 0.000
F23 Acute and transient psychotic disorders
0.714 0.285 0.000
H35 Other retinal disorders
0.714 0.286 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.713 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.286 0.000
T36 Poisoning by systemic antibiotics
0.713 0.286 0.000
S05 Injury of eye and orbit
0.712 0.288 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.712 0.288 0.000
M49 Spondylopathies in diseases classified elsewhere
0.711 0.288 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.711 0.289 0.000
E32 Diseases of thymus
0.711 0.289 0.000
E31 Polyglandular dysfunction
0.711 0.289 0.000
E30 Disorders of puberty, not elsewhere classified
0.711 0.289 0.000
E25 Adrenogenital disorders
0.711 0.289 0.000
E20 Hypoparathyroidism
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.289 0.000
Y10-Y34 Event of undetermined intent
0.710 0.289 0.000
X85-X99 Assault
0.710 0.289 0.000
X30-X39 Exposure to forces of nature
0.710 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.289 0.000
W65-W74 Accidental drowning and submersion
0.710 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.289 0.000
V95-V97 Air and space transport accidents
0.710 0.289 0.000
V90-V94 Water transport accidents
0.710 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.289 0.000
S08 Traumatic amputation of part of head
0.710 0.290 0.000
S07 Crushing injury of head
0.710 0.290 0.000
S04 Injury of cranial nerves
0.710 0.290 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.710 0.290 0.000
S02.8 Fractures of other skull and facial bones
0.710 0.290 0.000
E73 Lactose intolerance
0.709 0.291 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.709 0.291 0.000
M81 Osteoporosis without pathological fracture
0.709 0.291 0.000
W28 Contact with powered lawn mower
0.709 0.291 0.000
G96.0 Cerebrospinal fluid leak
0.708 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.707 0.293 0.000
M93 Other osteochondropathies
0.707 0.293 0.000
S06.3 Focal brain injury
0.706 0.294 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.706 0.294 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.704 0.296 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.703 0.297 0.000
T39.1 4-Aminophenol derivatives
0.703 0.297 0.000
S70-S79 Injuries to the hip and thigh
0.702 0.298 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
G95 Other diseases of spinal cord
0.701 0.299 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.700 0.300 0.000
S89 Other and unspecified injuries of lower leg
0.700 0.300 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.699 0.300 0.000
W25.9 Unspecified place
0.699 0.301 0.000
T51 Toxic effect of alcohol
0.699 0.301 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.699 0.301 0.000
S09.7 Multiple injuries of head
0.699 0.301 0.000
S09.2 Traumatic rupture of ear drum
0.699 0.301 0.000
S09.1 Injury of muscle and tendon of head
0.699 0.301 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.699 0.301 0.000
M48.09 Spinal stenosis (Site unspecified)
0.699 0.301 0.000
E87.4 Mixed disorder of acid-base balance
0.698 0.302 0.000
F03 Unspecified dementia
0.698 0.302 0.000
S02.30 Fracture of orbital floor (closed)
0.697 0.303 0.000
M51.9 Intervertebral disk disorder, unspecified
0.695 0.305 0.000
H43 Disorders of vitreous body
0.695 0.305 0.000
C95 Leukaemia of unspecified cell type
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
C34.9 Bronchus or lung, unspecified
0.693 0.307 0.000
G25 Other extrapyramidal and movement disorders
0.693 0.307 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.692 0.308 0.000
E34 Other endocrine disorders
0.691 0.309 0.000
Y40.8 Other systemic antibiotics
0.690 0.310 0.000
W07 Fall involving chair
0.689 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.689 0.311 0.000
Q43 Other congenital malformations of intestine
0.688 0.312 0.000
G64 Other disorders of peripheral nervous system
0.688 0.312 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.687 0.313 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.686 0.314 0.000
F70-F79 Mental retardation
0.686 0.314 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.686 0.314 0.000
S90-S99 Injuries to the ankle and foot
0.686 0.314 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.685 0.315 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.684 0.315 0.000
S60-S69 Injuries to the wrist and hand
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
M82 Osteoporosis in diseases classified elsewhere
0.684 0.316 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.683 0.317 0.000
T90.5 Sequelae of intracranial injury
0.683 0.317 0.000
S19 Other and unspecified injuries of neck
0.683 0.317 0.000
S80 Superficial injury of lower leg
0.682 0.318 0.000
S02.00 Fracture of vault of skull (closed)
0.682 0.318 0.000
G60 Hereditary and idiopathic neuropathy
0.681 0.319 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.681 0.319 0.000
S02.7 Multiple fractures involving skull and facial bones
0.681 0.319 0.000
D05.0 Lobular carcinoma in situ
0.680 0.320 0.000
E88 Other metabolic disorders
0.680 0.320 0.000
S11 Open wound of neck
0.680 0.320 0.000
T14.0 Superficial injury of unspecified body region
0.679 0.321 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.678 0.322 0.000
S27.1 Traumatic haemothorax
0.677 0.323 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.677 0.323 0.000
E53.8 Deficiency of other specified B group vitamins
0.677 0.323 0.000
E61 Deficiency of other nutrient elements
0.677 0.323 0.000
H10-H13 Disorders of conjunctiva
0.677 0.323 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.676 0.324 0.000
S42.20 Fracture of upper end of humerus (closed)
0.676 0.324 0.000
M50 Cervical disk disorders
0.675 0.325 0.000
S20 Superficial injury of thorax
0.675 0.325 0.000
G62.2 Polyneuropathy due to other toxic agents
0.674 0.326 0.000
G62.1 Alcoholic polyneuropathy
0.674 0.326 0.000
V20-V29 Motorcycle rider injured in transport accident
0.674 0.326 0.000
S82.2 Fracture of shaft of tibia
0.674 0.326 0.000
S82.7 Multiple fractures of lower leg
0.673 0.327 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.672 0.328 0.000
G03 Meningitis due to other and unspecified causes
0.672 0.328 0.000
G00 Bacterial meningitis, not elsewhere classified
0.672 0.328 0.000
W17 Other fall from one level to another
0.671 0.329 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.671 0.329 0.000
Q35-Q37 Cleft lip and cleft palate
0.671 0.329 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.671 0.329 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.671 0.329 0.000
G12.2 Motor neuron disease
0.670 0.330 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
E28.3 Primary ovarian failure
0.669 0.331 0.000
Y52 Agents primarily affecting the cardiovascular system
0.668 0.332 0.000
A40 Streptococcal septicaemia
0.668 0.332 0.000
X41.9 Unspecified place
0.667 0.333 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.667 0.333 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.667 0.333 0.000
S02.10 Fracture of base of skull (closed)
0.666 0.334 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.666 0.334 0.000
F01.9 Vascular dementia, unspecified
0.666 0.334 0.000
H04.2 Epiphora
0.665 0.335 0.000
S82.5 Fracture of medial malleolus
0.665 0.335 0.000
G51.0 Bell's palsy
0.664 0.335 0.000
G80 Infantile cerebral palsy
0.664 0.335 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.336 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.664 0.336 0.000
C09 Malignant neoplasm of tonsil
0.664 0.336 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.663 0.337 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.662 0.338 0.000
S26 Injury of heart
0.662 0.338 0.000
S25 Injury of blood vessels of thorax
0.662 0.338 0.000
S24 Injury of nerves and spinal cord at thorax level
0.662 0.338 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.662 0.338 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.662 0.338 0.000
W44 Foreign body entering into or through eye or natural orifice
0.662 0.338 0.000
H31 Other disorders of choroid
0.661 0.339 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.661 0.339 0.000
E21.4 Other specified disorders of parathyroid gland
0.661 0.339 0.000
E21.2 Other hyperparathyroidism
0.661 0.339 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.661 0.339 0.000
M94.8 Other specified disorders of cartilage
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.341 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.659 0.341 0.000
T59.8 Other specified gases, fumes and vapours
0.659 0.341 0.000
S06.4 Epidural haemorrhage
0.659 0.341 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.657 0.343 0.000
C94 Other leukaemias of specified cell type
0.657 0.343 0.000
C93 Monocytic leukaemia
0.657 0.343 0.000
C88 Malignant immunoproliferative diseases
0.657 0.343 0.000
C86 Other specified types of T/NK-cell lymphoma
0.657 0.343 0.000
T43.9 Psychotropic drug, unspecified
0.656 0.343 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.656 0.343 0.000
T43.6 Psychostimulants with abuse potential
0.656 0.343 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.656 0.343 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.656 0.343 0.000
T50.8 Diagnostic agents
0.656 0.344 0.000
T50.7 Analeptics and opioid receptor antagonists
0.656 0.344 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.656 0.344 0.000
T50.5 Appetite depressants
0.656 0.344 0.000
T50.4 Drugs affecting uric acid metabolism
0.656 0.344 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.656 0.344 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.656 0.344 0.000
T50.1 Loop [high-ceiling] diuretics
0.656 0.344 0.000
T50.0 Mineralocorticoids and their antagonists
0.656 0.344 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.656 0.344 0.000
F64 Gender identity disorders
0.656 0.344 0.000
C92 Myeloid leukaemia
0.656 0.344 0.000
H43.1 Vitreous haemorrhage
0.655 0.345 0.000
Y09 Assault by unspecified means
0.655 0.345 0.000
T14.1 Open wound of unspecified body region
0.653 0.347 0.000
F60 Specific personality disorders
0.653 0.347 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.652 0.348 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.651 0.349 0.000
T40.6 Other and unspecified narcotics
0.651 0.349 0.000
M48.9 Spondylopathy, unspecified
0.651 0.349 0.000
M48.8 Other specified spondylopathies
0.651 0.349 0.000
M48.4 Fatigue fracture of vertebra
0.651 0.349 0.000
M48.3 Traumatic spondylopathy
0.651 0.349 0.000
M48.2 Kissing spine
0.651 0.349 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.651 0.349 0.000
M40-M43 Deforming dorsopathies
0.650 0.350 0.000
G91 Hydrocephalus
0.650 0.350 0.000
C05 Malignant neoplasm of palate
0.650 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.649 0.351 0.000
Y58 Bacterial vaccines
0.649 0.351 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.649 0.351 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.649 0.351 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.649 0.351 0.000
Y48 Anaesthetics and therapeutic gases
0.649 0.351 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.649 0.351 0.000
C82.0 Small cleaved cell, follicular
0.649 0.351 0.000
G62.0 Drug-induced polyneuropathy
0.649 0.351 0.000
T13 Other injuries of lower limb, level unspecified
0.648 0.352 0.000
T11 Other injuries of upper limb, level unspecified
0.648 0.352 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.648 0.352 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.648 0.352 0.000
T12 Fracture of lower limb, level unspecified
0.648 0.352 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.648 0.352 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.648 0.352 0.000
T10 Fracture of upper limb, level unspecified
0.648 0.352 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.648 0.352 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.648 0.352 0.000
T08 Fracture of spine, level unspecified
0.648 0.352 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.647 0.352 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.647 0.353 0.000
F28 Other nonorganic psychotic disorders
0.647 0.353 0.000
F24 Induced delusional disorder
0.647 0.353 0.000
F21 Schizotypal disorder
0.647 0.353 0.000
S32 Fracture of lumbar spine and pelvis
0.647 0.353 0.000
F99-F99 Unspecified mental disorder
0.646 0.354 0.000
M62.8 Other specified disorders of muscle
0.646 0.354 0.000
D05.1 Intraductal carcinoma in situ
0.646 0.354 0.000
C81 Hodgkin's disease
0.646 0.354 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.646 0.354 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.645 0.355 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.645 0.355 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.645 0.355 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.645 0.355 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.645 0.355 0.000
M83 Adult osteomalacia
0.644 0.356 0.000
W29.9 Unspecified place
0.644 0.356 0.000
F02 Dementia in other diseases classified elsewhere
0.643 0.357 0.000
X60-X84 Intentional self-harm
0.643 0.357 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.643 0.357 0.000
S02.60 Fracture of mandible (closed)
0.643 0.357 0.000
Q07 Other congenital malformations of nervous system
0.641 0.358 0.000
S17 Crushing injury of neck
0.641 0.358 0.000
S15 Injury of blood vessels at neck level
0.641 0.358 0.000
S14 Injury of nerves and spinal cord at neck level
0.641 0.358 0.000
S18 Traumatic amputation at neck level
0.641 0.358 0.000
S16 Injury of muscle and tendon at neck level
0.641 0.358 0.000
W46 Contact with hypodermic needle
0.641 0.359 0.000
W45 Foreign body or object entering through skin
0.641 0.359 0.000
W43 Exposure to vibration
0.641 0.359 0.000
W42 Exposure to noise
0.641 0.359 0.000
W41 Exposure to high-pressure jet
0.641 0.359 0.000
W40 Explosion of other materials
0.641 0.359 0.000
W39 Discharge of firework
0.641 0.359 0.000
W38 Explosion and rupture of other specified pressurised devices
0.641 0.359 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.641 0.359 0.000
W36 Explosion and rupture of gas cylinder
0.641 0.359 0.000
W35 Explosion and rupture of boiler
0.641 0.359 0.000
W34 Discharge from other and unspecified firearms
0.641 0.359 0.000
W33 Rifle, shotgun and larger firearm discharge
0.641 0.359 0.000
W32 Handgun discharge
0.641 0.359 0.000
W31 Contact with other and unspecified machinery
0.641 0.359 0.000
W30 Contact with agricultural machinery
0.641 0.359 0.000
W27 Contact with nonpowered hand tool
0.641 0.359 0.000
W26 Contact with knife, sword or dagger
0.641 0.359 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.641 0.359 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.641 0.359 0.000
W20 Struck by thrown, projected or falling object
0.641 0.359 0.000
E27.9 Disorder of adrenal gland, unspecified
0.641 0.359 0.000
E27.5 Adrenomedullary hyperfunction
0.641 0.359 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.641 0.359 0.000
E27.0 Other adrenocortical overactivity
0.641 0.359 0.000
S10 Superficial injury of neck
0.641 0.359 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.641 0.359 0.000
G90 Disorders of autonomic nervous system
0.641 0.359 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.641 0.359 0.000
G92 Toxic encephalopathy
0.641 0.359 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.639 0.361 0.000
S88 Traumatic amputation of lower leg
0.639 0.361 0.000
S87 Crushing injury of lower leg
0.639 0.361 0.000
S85 Injury of blood vessels at lower leg level
0.639 0.361 0.000
S84 Injury of nerves at lower leg level
0.639 0.361 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.639 0.361 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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