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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74675245
log Bayes Factor = 15.4641
Chromosome 5   position 119,097,407  (GRCh37) Explore rs74675245 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.997 0.003 0.000
E65-E68 Obesity and other hyperalimentation
0.992 0.008 0.000
I47 Paroxysmal tachycardia
0.989 0.011 0.000
M45-M49 Spondylopathies
0.989 0.011 0.000
E70-E90 Metabolic disorders
0.987 0.013 0.000
E66 Obesity
0.986 0.014 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.983 0.017 0.000
M70-M79 Other soft tissue disorders
0.983 0.017 0.000
M48 Other spondylopathies
0.979 0.021 0.000
I50 Heart failure
0.974 0.026 0.000
E10-E14 Diabetes mellitus
0.973 0.027 0.000
L60-L75 Disorders of skin appendages
0.972 0.028 0.000
I47.1 Supraventricular tachycardia
0.972 0.028 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.971 0.029 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.970 0.030 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.970 0.030 0.000
M48.0 Spinal stenosis
0.969 0.031 0.000
E78.0 Pure hypercholesterolaemia
0.966 0.034 0.000
Chapter II Neoplasms
0.961 0.039 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
E66.8 Other obesity
0.958 0.042 0.000
Chapter VIII Diseases of the ear and mastoid process
0.956 0.044 0.000
Chapter XXI Factors influencing health status and contact with health services
0.954 0.046 0.000
Chapter VII Diseases of the eye and adnexa
0.948 0.052 0.000
E66.9 Obesity, unspecified
0.944 0.056 0.000
E10 Insulin-dependent diabetes mellitus
0.943 0.057 0.000
I50.0 Congestive heart failure
0.942 0.058 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.942 0.058 0.000
L82 Seborrhoeic keratosis
0.939 0.061 0.000
M48.06 Spinal stenosis (Lumbar region)
0.937 0.063 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.932 0.068 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.926 0.074 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.924 0.076 0.000
H90-H95 Other disorders of ear
0.919 0.081 0.000
I60-I69 Cerebrovascular diseases
0.911 0.089 0.000
I51 Complications and ill-defined descriptions of heart disease
0.907 0.093 0.000
M40-M43 Deforming dorsopathies
0.907 0.093 0.000
Chapter X Diseases of the respiratory system
0.905 0.095 0.000
C64-C68 Malignant neoplasms of urinary tract
0.904 0.096 0.000
C50-C50 Malignant neoplasm of breast
0.900 0.100 0.000
M06 Other rheumatoid arthritis
0.896 0.104 0.000
M79.0 Rheumatism, unspecified
0.894 0.106 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.891 0.109 0.000
H25-H28 Disorders of lens
0.886 0.114 0.000
L72.1 Trichilemmal cyst
0.885 0.115 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.884 0.116 0.000
E20-E35 Disorders of other endocrine glands
0.881 0.119 0.000
M13 Other arthritis
0.879 0.121 0.000
I80 Phlebitis and thrombophlebitis
0.872 0.128 0.000
C67 Malignant neoplasm of bladder
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.871 0.129 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.870 0.130 0.000
C50 Malignant neoplasm of breast
0.856 0.144 0.000
J09-J18 Influenza and pneumonia
0.856 0.144 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.855 0.145 0.000
I44 Atrioventricular and left bundle-branch block
0.852 0.148 0.000
Z53.0 Procedure not carried out because of contraindication
0.850 0.150 0.000
M79.6 Pain in limb
0.847 0.153 0.000
Z03.8 Observation for other suspected diseases and conditions
0.847 0.153 0.000
I46 Cardiac arrest
0.846 0.154 0.000
C60-C63 Malignant neoplasms of male genital organs
0.845 0.155 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.842 0.158 0.000
C67.9 Bladder, unspecified
0.840 0.160 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.839 0.161 0.000
I50.1 Left ventricular failure
0.838 0.162 0.000
L60 Nail disorders
0.838 0.162 0.000
E10.3 With ophthalmic complications
0.836 0.164 0.000
M43 Other deforming dorsopathies
0.834 0.166 0.000
Z03.4 Observation for suspected myocardial infarction
0.832 0.168 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.831 0.169 0.000
H25 Senile cataract
0.830 0.170 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.827 0.173 0.000
M06.9 Rheumatoid arthritis, unspecified
0.826 0.174 0.000
E00-E07 Disorders of thyroid gland
0.825 0.175 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.825 0.175 0.000
H92 Otalgia and effusion of ear
0.821 0.179 0.000
M48.09 Spinal stenosis (Site unspecified)
0.820 0.180 0.000
J90-J94 Other diseases of pleura
0.819 0.181 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.819 0.181 0.000
L85 Other epidermal thickening
0.818 0.182 0.000
R07 Pain in throat and chest
0.817 0.183 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.817 0.183 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.816 0.184 0.000
G90-G99 Other disorders of the nervous system
0.814 0.186 0.000
M79.7 Fibromyalgia
0.812 0.188 0.000
J18 Pneumonia, organism unspecified
0.812 0.188 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.811 0.189 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.808 0.192 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.807 0.193 0.000
L89 Decubitus ulcer
0.807 0.193 0.000
I47.2 Ventricular tachycardia
0.805 0.195 0.000
E10.9 Without complications
0.804 0.196 0.000
Z12 Special screening examination for neoplasms
0.802 0.198 0.000
C50.9 Breast, unspecified
0.801 0.199 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.801 0.199 0.000
L50-L54 Urticaria and erythema
0.800 0.200 0.000
R07.4 Chest pain, unspecified
0.799 0.201 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.799 0.201 0.000
I42 Cardiomyopathy
0.798 0.202 0.000
I51.7 Cardiomegaly
0.798 0.202 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.797 0.202 0.000
E10.4 With neurological complications
0.797 0.203 0.000
H25.0 Senile incipient cataract
0.792 0.208 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.791 0.209 0.000
M79.8 Other specified soft tissue disorders
0.789 0.211 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.788 0.212 0.000
E11 Non-insulin-dependent diabetes mellitus
0.783 0.217 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.782 0.218 0.000
M43.1 Spondylolisthesis
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.780 0.220 0.000
M13.9 Arthritis, unspecified
0.779 0.221 0.000
M50-M54 Other dorsopathies
0.779 0.221 0.000
H93 Other disorders of ear, not elsewhere classified
0.779 0.221 0.000
M86-M90 Other osteopathies
0.777 0.223 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.777 0.223 0.000
M79.1 Myalgia
0.775 0.225 0.000
L93 Lupus erythematosus
0.774 0.226 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.773 0.227 0.000
I83 Varicose veins of lower extremities
0.772 0.228 0.000
H60-H62 Diseases of external ear
0.772 0.228 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.767 0.233 0.000
I51.9 Heart disease, unspecified
0.767 0.233 0.000
M77 Other enthesopathies
0.767 0.233 0.000
H25.8 Other senile cataract
0.766 0.234 0.000
L20-L30 Dermatitis and eczema
0.766 0.234 0.000
E50-E64 Other nutritional deficiencies
0.765 0.235 0.000
I46.0 Cardiac arrest with successful resuscitation
0.762 0.238 0.000
C61 Malignant neoplasm of prostate
0.762 0.238 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.760 0.240 0.000
M45 Ankylosing spondylitis
0.758 0.242 0.000
J18.1 Lobar pneumonia, unspecified
0.758 0.242 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
L40-L45 Papulosquamous disorders
0.756 0.244 0.000
R05 Cough
0.756 0.244 0.000
E10.1 With ketoacidosis
0.753 0.247 0.000
E04 Other non-toxic goitre
0.752 0.248 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.750 0.250 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
G40-G47 Episodic and paroxysmal disorders
0.749 0.251 0.000
D00-D09 In situ neoplasms
0.748 0.252 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.748 0.252 0.000
Chapter XX External causes of morbidity and mortality
0.748 0.252 0.000
I67 Other cerebrovascular diseases
0.747 0.253 0.000
I30 Acute pericarditis
0.746 0.254 0.000
E88 Other metabolic disorders
0.745 0.255 0.000
I38 Endocarditis, valve unspecified
0.745 0.255 0.000
L84 Corns and callosities
0.743 0.257 0.000
H00 Hordeolum and chalazion
0.740 0.260 0.000
I87 Other disorders of veins
0.740 0.260 0.000
J20-J22 Other acute lower respiratory infections
0.738 0.262 0.000
Z53.9 Procedure not carried out, unspecified reason
0.738 0.262 0.000
H10-H13 Disorders of conjunctiva
0.738 0.262 0.000
M81 Osteoporosis without pathological fracture
0.737 0.263 0.000
H90 Conductive and sensorineural hearing loss
0.737 0.263 0.000
L71 Rosacea
0.736 0.264 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.736 0.264 0.000
M13.0 Polyarthritis, unspecified
0.735 0.264 0.000
Z48 Other surgical follow-up care
0.733 0.267 0.000
J90 Pleural effusion, not elsewhere classified
0.733 0.267 0.000
M71 Other bursopathies
0.733 0.267 0.000
M06.0 Seronegative rheumatoid arthritis
0.731 0.269 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.730 0.270 0.000
H91 Other hearing loss
0.729 0.271 0.000
D10-D36 Benign neoplasms
0.727 0.273 0.000
J60-J70 Lung diseases due to external agents
0.725 0.275 0.000
M48.02 Spinal stenosis (Cervical region)
0.725 0.275 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.723 0.277 0.000
I44.2 Atrioventricular block, complete
0.723 0.277 0.000
C50.5 Lower-outer quadrant of breast
0.723 0.277 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.723 0.277 0.000
E27 Other disorders of adrenal gland
0.722 0.278 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.721 0.278 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.720 0.280 0.000
Z44 Fitting and adjustment of external prosthetic device
0.719 0.281 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E24 Cushing's syndrome
0.716 0.284 0.000
M79.66 Pain in limb (Lower leg)
0.715 0.285 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.715 0.285 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.715 0.285 0.000
L94 Other localised connective tissue disorders
0.715 0.285 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.715 0.285 0.000
L87 Transepidermal elimination disorders
0.715 0.285 0.000
L88 Pyoderma gangrenosum
0.715 0.285 0.000
L86 Keratoderma in diseases classified elsewhere
0.715 0.285 0.000
L83 Acanthosis nigricans
0.715 0.285 0.000
L80 Vitiligo
0.715 0.285 0.000
M75 Shoulder lesions
0.715 0.285 0.000
M46 Other inflammatory spondylopathies
0.715 0.285 0.000
E14 Unspecified diabetes mellitus
0.714 0.286 0.000
R07.2 Precordial pain
0.713 0.287 0.000
E87.0 Hyperosmolality and hypernatraemia
0.713 0.287 0.000
E22 Hyperfunction of pituitary gland
0.711 0.289 0.000
E67 Other hyperalimentation
0.711 0.289 0.000
E68 Sequelae of hyperalimentation
0.711 0.289 0.000
E65 Localised adiposity
0.711 0.289 0.000
I85 Oesophageal varices
0.711 0.289 0.000
L81 Other disorders of pigmentation
0.710 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
I47.0 Reentry ventricular arrhythmia
0.709 0.291 0.000
M49 Spondylopathies in diseases classified elsewhere
0.709 0.291 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.709 0.291 0.000
E85 Amyloidosis
0.708 0.292 0.000
E84 Cystic fibrosis
0.708 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.708 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.708 0.292 0.000
E73 Lactose intolerance
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.292 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.707 0.293 0.000
E66.1 Drug-induced obesity
0.707 0.293 0.000
E66.0 Obesity due to excess calories
0.707 0.293 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.707 0.293 0.000
H92.1 Otorrhoea
0.707 0.293 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.706 0.294 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.705 0.295 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.705 0.295 0.000
L98.5 Mucinosis of skin
0.705 0.295 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.705 0.295 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.705 0.295 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.705 0.295 0.000
L98.1 Factitial dermatitis
0.705 0.295 0.000
M76 Enthesopathies of lower limb, excluding foot
0.705 0.295 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.705 0.295 0.000
L72.0 Epidermal cyst
0.704 0.296 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.702 0.298 0.000
M48.9 Spondylopathy, unspecified
0.702 0.298 0.000
M48.8 Other specified spondylopathies
0.702 0.298 0.000
M48.4 Fatigue fracture of vertebra
0.702 0.298 0.000
M48.3 Traumatic spondylopathy
0.702 0.298 0.000
M48.2 Kissing spine
0.702 0.298 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.702 0.298 0.000
M47 Spondylosis
0.701 0.299 0.000
H43-H45 Disorders of vitreous body and globe
0.699 0.301 0.000
J92 Pleural plaque
0.699 0.301 0.000
M79.79 Fibromyalgia (Site unspecified)
0.698 0.302 0.000
E13 Other specified diabetes mellitus
0.697 0.302 0.000
E12 Malnutrition-related diabetes mellitus
0.697 0.302 0.000
L75 Apocrine sweat disorders
0.697 0.303 0.000
L74 Eccrine sweat disorders
0.697 0.303 0.000
L73 Other follicular disorders
0.697 0.303 0.000
L70 Acne
0.697 0.303 0.000
L68 Hypertrichosis
0.697 0.303 0.000
L67 Hair colour and hair shaft abnormalities
0.697 0.303 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.697 0.303 0.000
L65 Other nonscarring hair loss
0.697 0.303 0.000
L64 Androgenic alopecia
0.697 0.303 0.000
L63 Alopecia areata
0.697 0.303 0.000
L62 Nail disorders in diseases classified elsewhere
0.697 0.303 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.697 0.303 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.697 0.303 0.000
I62 Other nontraumatic intracranial haemorrhage
0.696 0.304 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.696 0.304 0.000
E78.8 Other disorders of lipoprotein metabolism
0.696 0.304 0.000
E78.6 Lipoprotein deficiency
0.696 0.304 0.000
E78.4 Other hyperlipidaemia
0.696 0.304 0.000
E78.3 Hyperchylomicronaemia
0.696 0.304 0.000
E78.2 Mixed hyperlipidaemia
0.696 0.304 0.000
E78.1 Pure hyperglyceridaemia
0.696 0.304 0.000
M79.9 Soft tissue disorder, unspecified
0.696 0.304 0.000
M79.5 Residual foreign body in soft tissue
0.696 0.304 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.696 0.304 0.000
M79.3 Panniculitis, unspecified
0.696 0.304 0.000
M79.2 Neuralgia and neuritis, unspecified
0.696 0.304 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.695 0.305 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.695 0.305 0.000
M48.04 Spinal stenosis (Thoracic region)
0.695 0.305 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.695 0.305 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.695 0.305 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.695 0.305 0.000
E86 Volume depletion
0.695 0.305 0.000
I89.0 Lymphoedema, not elsewhere classified
0.694 0.306 0.000
C51-C58 Malignant neoplasms of female genital organs
0.693 0.306 0.000
E89.0 Postprocedural hypothyroidism
0.693 0.307 0.000
Z53.8 Procedure not carried out for other reasons
0.692 0.308 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
I45 Other conduction disorders
0.690 0.310 0.000
H30-H36 Disorders of choroid and retina
0.689 0.310 0.000
L60.0 Ingrowing nail
0.689 0.311 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.689 0.311 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.689 0.311 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.689 0.311 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.689 0.311 0.000
L85.8 Other specified epidermal thickening
0.689 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.688 0.311 0.000
M12 Other specific arthropathies
0.688 0.311 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.688 0.311 0.000
M08 Juvenile arthritis
0.688 0.311 0.000
J18.9 Pneumonia, unspecified
0.688 0.312 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.687 0.313 0.000
H26 Other cataract
0.687 0.313 0.000
M11 Other crystal arthropathies
0.685 0.315 0.000
I31 Other diseases of pericardium
0.685 0.315 0.000
C67.2 Lateral wall of bladder
0.684 0.315 0.000
L60.8 Other nail disorders
0.683 0.317 0.000
M13.93 Arthritis, unspecified (Forearm)
0.682 0.318 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.682 0.318 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.681 0.319 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.681 0.319 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.681 0.319 0.000
C73 Malignant neoplasm of thyroid gland
0.680 0.320 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.680 0.320 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.680 0.320 0.000
I44.0 Atrioventricular block, first degree
0.679 0.321 0.000
L05 Pilonidal cyst
0.679 0.321 0.000
H92.0 Otalgia
0.679 0.321 0.000
H93.1 Tinnitus
0.678 0.322 0.000
M79.64 Pain in limb (Hand)
0.677 0.323 0.000
I34 Nonrheumatic mitral valve disorders
0.677 0.323 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.676 0.324 0.000
E10.8 With unspecified complications
0.676 0.324 0.000
E10.7 With multiple complications
0.676 0.324 0.000
E10.6 With other specified complications
0.676 0.324 0.000
E10.5 With peripheral circulatory complications
0.676 0.324 0.000
E10.2 With renal complications
0.676 0.324 0.000
E10.0 With coma
0.676 0.324 0.000
I88 Nonspecific lymphadenitis
0.675 0.325 0.000
I82 Other venous embolism and thrombosis
0.675 0.325 0.000
I81 Portal vein thrombosis
0.675 0.325 0.000
M07 Psoriatic and enteropathic arthropathies
0.675 0.325 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.675 0.325 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.674 0.326 0.000
M41 Scoliosis
0.673 0.327 0.000
E87.5 Hyperkalaemia
0.672 0.328 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.672 0.328 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.672 0.328 0.000
H55-H59 Other disorders of eye and adnexa
0.671 0.329 0.000
C50.2 Upper-inner quadrant of breast
0.671 0.329 0.000
G91 Hydrocephalus
0.671 0.329 0.000
L98.0 Pyogenic granuloma
0.670 0.330 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.669 0.331 0.000
Z10 Routine general health check-up of defined subpopulation
0.668 0.332 0.000
I50.9 Heart failure, unspecified
0.668 0.332 0.000
I86 Varicose veins of other sites
0.667 0.333 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.666 0.334 0.000
H65-H75 Diseases of middle ear and mastoid
0.666 0.334 0.000
M79.63 Pain in limb (Forearm)
0.665 0.334 0.000
G20-G26 Extrapyramidal and movement disorders
0.665 0.335 0.000
Z03.3 Observation for suspected nervous system disorder
0.665 0.335 0.000
M05 Seropositive rheumatoid arthritis
0.664 0.336 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.664 0.336 0.000
L72.2 Steatocystoma multiplex
0.664 0.336 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.664 0.336 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.663 0.336 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.663 0.337 0.000
C50.4 Upper-outer quadrant of breast
0.663 0.337 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.663 0.337 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.662 0.337 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.662 0.337 0.000
Z03.0 Observation for suspected tuberculosis
0.662 0.337 0.000
M65-M68 Disorders of synovium and tendon
0.662 0.338 0.000
R00 Abnormalities of heart beat
0.662 0.338 0.000
G93 Other disorders of brain
0.661 0.339 0.000
E04.9 Non-toxic goitre, unspecified
0.661 0.339 0.000
M80 Osteoporosis with pathological fracture
0.660 0.340 0.000
L91 Hypertrophic disorders of skin
0.660 0.340 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.660 0.340 0.000
L53 Other erythematous conditions
0.659 0.340 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.659 0.341 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.659 0.341 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.659 0.341 0.000
R79 Other abnormal findings of blood chemistry
0.659 0.341 0.000
M54 Dorsalgia
0.659 0.341 0.000
Z41 Procedures for purposes other than remedying health state
0.658 0.342 0.000
L08 Other local infections of skin and subcutaneous tissue
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
Z43 Attention to artificial openings
0.656 0.344 0.000
H00.1 Chalazion
0.655 0.345 0.000
J11 Influenza, virus not identified
0.655 0.345 0.000
I26 Pulmonary embolism
0.654 0.346 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.653 0.346 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.653 0.346 0.000
E11.3 With ophthalmic complications
0.653 0.347 0.000
O00-O08 Pregnancy with abortive outcome
0.653 0.347 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.653 0.347 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.652 0.348 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.652 0.348 0.000
M85 Other disorders of bone density and structure
0.650 0.349 0.000
I51.6 Cardiovascular disease, unspecified
0.650 0.350 0.000
I51.5 Myocardial degeneration
0.650 0.350 0.000
I51.4 Myocarditis, unspecified
0.650 0.350 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.650 0.350 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.650 0.350 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.650 0.350 0.000
I51.0 Cardiac septal defect, acquired
0.650 0.350 0.000
M42 Spinal osteochondrosis
0.650 0.350 0.000
M40 Kyphosis and lordosis
0.650 0.350 0.000
M84 Disorders of continuity of bone
0.650 0.350 0.000
H05 Disorders of orbit
0.649 0.351 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.649 0.351 0.000
I89.1 Lymphangitis
0.649 0.351 0.000
H01 Other inflammation of eyelid
0.649 0.351 0.000
R02 Gangrene, not elsewhere classified
0.649 0.351 0.000
H80-H83 Diseases of inner ear
0.648 0.352 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.648 0.352 0.000
C66 Malignant neoplasm of ureter
0.648 0.352 0.000
C65 Malignant neoplasm of renal pelvis
0.648 0.352 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.648 0.352 0.000
J95-J99 Other diseases of the respiratory system
0.645 0.355 0.000
I69 Sequelae of cerebrovascular disease
0.645 0.355 0.000
E11.2 With renal complications
0.644 0.356 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.644 0.356 0.000
M06.8 Other specified rheumatoid arthritis
0.643 0.357 0.000
M06.4 Inflammatory polyarthropathy
0.643 0.357 0.000
M06.3 Rheumatoid nodule
0.643 0.357 0.000
M06.2 Rheumatoid bursitis
0.643 0.357 0.000
M06.1 Adult-onset Still's disease
0.643 0.357 0.000
M79.69 Pain in limb (Site unspecified)
0.642 0.358 0.000
M81.9 Osteoporosis, unspecified
0.641 0.359 0.000
M79.08 Rheumatism, unspecified (Other)
0.641 0.359 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.641 0.359 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.641 0.359 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.641 0.359 0.000
M79.04 Rheumatism, unspecified (Hand)
0.641 0.359 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.641 0.359 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.641 0.359 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.641 0.359 0.000
H53-H54 Visual disturbances and blindness
0.641 0.359 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.641 0.359 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.640 0.360 0.000
G30-G32 Other degenerative diseases of the nervous system
0.639 0.361 0.000
I49 Other cardiac arrhythmias
0.639 0.361 0.000
I27 Other pulmonary heart diseases
0.637 0.363 0.000
I63 Cerebral infarction
0.637 0.363 0.000
G44 Other headache syndromes
0.636 0.363 0.000
M79.19 Myalgia (Site unspecified)
0.636 0.364 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.635 0.365 0.000
H27 Other disorders of lens
0.635 0.365 0.000
Z54 Convalescence
0.634 0.366 0.000
Z52 Donors of organs and tissues
0.634 0.366 0.000
Z49 Care involving dialysis
0.634 0.366 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.632 0.368 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.632 0.368 0.000
E34 Other endocrine disorders
0.632 0.368 0.000
E32 Diseases of thymus
0.632 0.368 0.000
E31 Polyglandular dysfunction
0.632 0.368 0.000
E30 Disorders of puberty, not elsewhere classified
0.632 0.368 0.000
E29 Testicular dysfunction
0.632 0.368 0.000
E28 Ovarian dysfunction
0.632 0.368 0.000
E26 Hyperaldosteronism
0.632 0.368 0.000
E25 Adrenogenital disorders
0.632 0.368 0.000
E23 Hypofunction and other disorders of pituitary gland
0.632 0.368 0.000
E20 Hypoparathyroidism
0.632 0.368 0.000
M13.8 Other specified arthritis
0.630 0.369 0.000
M13.1 Monoarthritis, not elsewhere classified
0.630 0.369 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.629 0.371 0.000
S80-S89 Injuries to the knee and lower leg
0.629 0.371 0.000
Z48.9 Surgical follow-up care, unspecified
0.628 0.372 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.627 0.373 0.000
I61 Intracerebral haemorrhage
0.627 0.373 0.000
Z50 Care involving use of rehabilitation procedures
0.626 0.374 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.625 0.375 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.625 0.375 0.000
E87.6 Hypokalaemia
0.625 0.375 0.000
G95 Other diseases of spinal cord
0.625 0.375 0.000
L29 Pruritus
0.625 0.375 0.000
S50-S59 Injuries to the elbow and forearm
0.625 0.375 0.000
M75.4 Impingement syndrome of shoulder
0.625 0.375 0.000
R07.0 Pain in throat
0.625 0.375 0.000
C67.8 Overlapping lesion of bladder
0.625 0.375 0.000
C67.7 Urachus
0.625 0.375 0.000
C67.6 Ureteric orifice
0.625 0.375 0.000
C67.5 Bladder neck
0.625 0.375 0.000
C67.4 Posterior wall of bladder
0.625 0.375 0.000
C67.3 Anterior wall of bladder
0.625 0.375 0.000
C67.1 Dome of bladder
0.625 0.375 0.000
C67.0 Trigone of bladder
0.625 0.375 0.000
M83 Adult osteomalacia
0.625 0.375 0.000
M82 Osteoporosis in diseases classified elsewhere
0.625 0.375 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.624 0.376 0.000
E11.1 With ketoacidosis
0.624 0.376 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.623 0.377 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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