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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74703823
log Bayes Factor = 12.1497
Chromosome 3   position 3,162,708  (GRCh37) Explore rs74703823 on Ensembl!
Variant rs74703823 is part of Cluster X0247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
J30-J39 Other diseases of upper respiratory tract
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
E10 Insulin-dependent diabetes mellitus
0.987 0.013 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.985 0.015 0.000
G40-G47 Episodic and paroxysmal disorders
0.984 0.016 0.000
E10.9 Without complications
0.976 0.024 0.000
H53-H54 Visual disturbances and blindness
0.969 0.031 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.965 0.035 0.000
G47 Sleep disorders
0.961 0.039 0.000
S80-S89 Injuries to the knee and lower leg
0.958 0.042 0.000
G90-G99 Other disorders of the nervous system
0.952 0.048 0.000
M20 Acquired deformities of fingers and toes
0.951 0.049 0.000
G47.3 Sleep apnoea
0.949 0.051 0.000
S90-S99 Injuries to the ankle and foot
0.948 0.052 0.000
M23 Internal derangement of knee
0.945 0.055 0.000
M05-M14 Inflammatory polyarthropathies
0.943 0.057 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.937 0.063 0.000
K29.5 Chronic gastritis, unspecified
0.937 0.063 0.000
Chapter XI Diseases of the digestive system
0.936 0.064 0.000
K29 Gastritis and duodenitis
0.933 0.067 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.932 0.068 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.931 0.069 0.000
J33 Nasal polyp
0.930 0.070 0.000
H53 Visual disturbances
0.930 0.070 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.923 0.077 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.915 0.085 0.000
J35 Chronic diseases of tonsils and adenoids
0.915 0.085 0.000
S20-S29 Injuries to the thorax
0.912 0.088 0.000
M20.2 Hallux rigidus
0.911 0.089 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.909 0.091 0.000
J09-J18 Influenza and pneumonia
0.884 0.116 0.000
G93 Other disorders of brain
0.881 0.119 0.000
T79-T79 Certain early complications of trauma
0.881 0.119 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.880 0.120 0.000
H30-H36 Disorders of choroid and retina
0.875 0.125 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.875 0.125 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.872 0.128 0.000
H54 Blindness and low vision
0.867 0.133 0.000
J32 Chronic sinusitis
0.866 0.134 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.866 0.134 0.000
Chapter I Certain infectious and parasitic diseases
0.863 0.137 0.000
M21 Other acquired deformities of limbs
0.863 0.137 0.000
W20-W49 Exposure to inanimate mechanical forces
0.863 0.137 0.000
H53.2 Diplopia
0.862 0.138 0.000
K35-K38 Diseases of appendix
0.862 0.138 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.859 0.141 0.000
J90-J94 Other diseases of pleura
0.857 0.143 0.000
W00-W19 Falls
0.855 0.145 0.000
E11 Non-insulin-dependent diabetes mellitus
0.854 0.146 0.000
S82 Fracture of lower leg, including ankle
0.854 0.146 0.000
T42.4 Benzodiazepines
0.854 0.146 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.851 0.149 0.000
H55-H59 Other disorders of eye and adnexa
0.848 0.152 0.000
M13 Other arthritis
0.848 0.152 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.845 0.155 0.000
J33.9 Nasal polyp, unspecified
0.841 0.159 0.000
S92 Fracture of foot, except ankle
0.840 0.160 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.840 0.160 0.000
M24 Other specific joint derangements
0.839 0.160 0.000
J34 Other disorders of nose and nasal sinuses
0.837 0.163 0.000
M40-M43 Deforming dorsopathies
0.836 0.164 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.836 0.164 0.000
K21 Gastro-oesophageal reflux disease
0.835 0.165 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.834 0.166 0.000
M50-M54 Other dorsopathies
0.833 0.167 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.832 0.168 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.829 0.171 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.827 0.173 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.827 0.173 0.000
H35 Other retinal disorders
0.826 0.174 0.000
G30-G32 Other degenerative diseases of the nervous system
0.825 0.175 0.000
M20.4 Other hammer toe(s) (acquired)
0.824 0.176 0.000
M10 Gout
0.822 0.178 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.821 0.179 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.820 0.180 0.000
K35 Acute appendicitis
0.820 0.180 0.000
M45-M49 Spondylopathies
0.819 0.181 0.000
H53.8 Other visual disturbances
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
K90-K93 Other diseases of the digestive system
0.815 0.185 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.814 0.186 0.000
T91 Sequelae of injuries of neck and trunk
0.810 0.190 0.000
K29.0 Acute haemorrhagic gastritis
0.810 0.190 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.807 0.193 0.000
E10.2 With renal complications
0.807 0.193 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.807 0.193 0.000
M20.5 Other deformities of toe(s) (acquired)
0.805 0.195 0.000
M22 Disorders of patella
0.800 0.200 0.000
E16 Other disorders of pancreatic internal secretion
0.798 0.202 0.000
S91 Open wound of ankle and foot
0.797 0.203 0.000
G93.8 Other specified disorders of brain
0.796 0.204 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.796 0.204 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.795 0.205 0.000
K35.9 Acute appendicitis, unspecified
0.792 0.208 0.000
E40-E46 Malnutrition
0.792 0.208 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.791 0.209 0.000
E10.4 With neurological complications
0.790 0.210 0.000
M06 Other rheumatoid arthritis
0.790 0.210 0.000
E14 Unspecified diabetes mellitus
0.787 0.213 0.000
J35.1 Hypertrophy of tonsils
0.786 0.214 0.000
H35.3 Degeneration of macula and posterior pole
0.786 0.214 0.000
J34.3 Hypertrophy of nasal turbinates
0.786 0.214 0.000
J39 Other diseases of upper respiratory tract
0.784 0.216 0.000
M13.9 Arthritis, unspecified
0.784 0.216 0.000
Chapter XXII Codes for special purposes
0.783 0.217 0.000
Y95 Nosocomial condition
0.783 0.217 0.000
T92 Sequelae of injuries of upper limb
0.783 0.217 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.780 0.220 0.000
S90 Superficial injury of ankle and foot
0.780 0.220 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.780 0.220 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.780 0.220 0.000
S80 Superficial injury of lower leg
0.780 0.220 0.000
S60-S69 Injuries to the wrist and hand
0.778 0.222 0.000
T39.1 4-Aminophenol derivatives
0.777 0.223 0.000
J32.0 Chronic maxillary sinusitis
0.777 0.223 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.777 0.223 0.000
V80-V89 Other land transport accidents
0.773 0.227 0.000
M65-M68 Disorders of synovium and tendon
0.772 0.228 0.000
J33.0 Polyp of nasal cavity
0.769 0.231 0.000
S27 Injury of other and unspecified intrathoracic organs
0.768 0.232 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.767 0.233 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.767 0.233 0.000
Y52 Agents primarily affecting the cardiovascular system
0.766 0.234 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.765 0.234 0.000
J60-J70 Lung diseases due to external agents
0.765 0.235 0.000
K29.7 Gastritis, unspecified
0.765 0.235 0.000
S92.3 Fracture of metatarsal bone
0.764 0.236 0.000
G93.3 Postviral fatigue syndrome
0.763 0.237 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.763 0.237 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.760 0.240 0.000
X60-X84 Intentional self-harm
0.759 0.241 0.000
J10 Influenza due to identified influenza virus
0.758 0.242 0.000
T51 Toxic effect of alcohol
0.758 0.242 0.000
Y44 Agents primarily affecting blood constituents
0.757 0.243 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.757 0.243 0.000
J20-J22 Other acute lower respiratory infections
0.756 0.244 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.755 0.245 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.754 0.246 0.000
S00-S09 Injuries to the head
0.753 0.247 0.000
H53.0 Amblyopia ex anopsia
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.752 0.248 0.000
H54.0 Blindness, both eyes
0.751 0.249 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.751 0.249 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.751 0.249 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.750 0.250 0.000
E10.3 With ophthalmic complications
0.749 0.251 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.748 0.252 0.000
S10-S19 Injuries to the neck
0.747 0.253 0.000
T81 Complications of procedures, not elsewhere classified
0.745 0.255 0.000
H31 Other disorders of choroid
0.744 0.256 0.000
E11.4 With neurological complications
0.743 0.256 0.000
H43-H45 Disorders of vitreous body and globe
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.258 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.741 0.259 0.000
W29 Contact with other powered hand tools and household machinery
0.741 0.259 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
E10.1 With ketoacidosis
0.740 0.260 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.740 0.260 0.000
T39.0 Salicylates
0.740 0.260 0.000
E16.2 Hypoglycaemia, unspecified
0.739 0.261 0.000
G70-G73 Diseases of myoneural junction and muscle
0.739 0.261 0.000
S82.1 Fracture of upper end of tibia
0.739 0.261 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.738 0.262 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.737 0.263 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.737 0.263 0.000
M10.9 Gout, unspecified
0.736 0.264 0.000
M23.9 Internal derangement of knee, unspecified
0.735 0.265 0.000
H54.7 Unspecified visual loss
0.734 0.266 0.000
J37 Chronic laryngitis and laryngotracheitis
0.733 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.733 0.267 0.000
B99-B99 Other infectious diseases
0.733 0.267 0.000
M34 Systemic sclerosis
0.733 0.267 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.732 0.268 0.000
G90 Disorders of autonomic nervous system
0.731 0.269 0.000
M20.0 Deformity of finger(s)
0.731 0.269 0.000
M25 Other joint disorders, not elsewhere classified
0.730 0.270 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.729 0.271 0.000
J31.0 Chronic rhinitis
0.728 0.272 0.000
T79.7 Traumatic subcutaneous emphysema
0.728 0.272 0.000
S81 Open wound of lower leg
0.727 0.272 0.000
M21.1 Varus deformity, not elsewhere classified
0.726 0.274 0.000
Y57 Other and unspecified drugs and medicaments
0.726 0.274 0.000
M91-M94 Chondropathies
0.725 0.275 0.000
T90 Sequelae of injuries of head
0.725 0.275 0.000
J32.2 Chronic ethmoidal sinusitis
0.725 0.275 0.000
M00-M03 Infectious arthropathies
0.724 0.276 0.000
G91 Hydrocephalus
0.723 0.277 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.722 0.278 0.000
E10.5 With peripheral circulatory complications
0.721 0.279 0.000
M41 Scoliosis
0.719 0.281 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.716 0.284 0.000
Y86 Sequelae of other accidents
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
K29.8 Duodenitis
0.714 0.286 0.000
M31 Other necrotising vasculopathies
0.714 0.286 0.000
T45.0 Antiallergic and antiemetic drugs
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
J33.8 Other polyp of sinus
0.711 0.289 0.000
G20-G26 Extrapyramidal and movement disorders
0.710 0.290 0.000
W25 Contact with sharp glass
0.710 0.290 0.000
S92.30 Fracture of metatarsal bone (closed)
0.709 0.291 0.000
S83.2 Tear of meniscus, current
0.709 0.291 0.000
M22.8 Other disorders of patella
0.708 0.291 0.000
E10.8 With unspecified complications
0.707 0.292 0.000
E10.7 With multiple complications
0.707 0.292 0.000
E10.6 With other specified complications
0.707 0.292 0.000
E10.0 With coma
0.707 0.292 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.294 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.294 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.706 0.294 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.294 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.294 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.294 0.000
T36 Poisoning by systemic antibiotics
0.706 0.294 0.000
H46 Optic neuritis
0.706 0.294 0.000
H57 Other disorders of eye and adnexa
0.706 0.294 0.000
G41 Status epilepticus
0.706 0.294 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.706 0.294 0.000
J90 Pleural effusion, not elsewhere classified
0.705 0.295 0.000
G59.0 Diabetic mononeuropathy
0.705 0.295 0.000
T91.1 Sequelae of fracture of spine
0.705 0.295 0.000
E13 Other specified diabetes mellitus
0.704 0.295 0.000
K92 Other diseases of digestive system
0.705 0.295 0.000
S82.6 Fracture of lateral malleolus
0.704 0.296 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.704 0.296 0.000
E11.2 With renal complications
0.703 0.297 0.000
W10 Fall on and from stairs and steps
0.702 0.298 0.000
G44 Other headache syndromes
0.701 0.298 0.000
E11.3 With ophthalmic complications
0.701 0.299 0.000
G11 Hereditary ataxia
0.700 0.300 0.000
H55 Nystagmus and other irregular eye movements
0.699 0.301 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.699 0.301 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.699 0.301 0.000
H02 Other disorders of eyelid
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.698 0.302 0.000
T93 Sequelae of injuries of lower limb
0.696 0.304 0.000
J14 Pneumonia due to Haemophilus influenzae
0.695 0.305 0.000
M54 Dorsalgia
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.692 0.308 0.000
Y58 Bacterial vaccines
0.692 0.308 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.692 0.308 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.692 0.308 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
Y48 Anaesthetics and therapeutic gases
0.692 0.308 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.692 0.308 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.692 0.308 0.000
G46.7 Other lacunar syndromes
0.692 0.308 0.000
H53.9 Visual disturbance, unspecified
0.692 0.308 0.000
G58 Other mononeuropathies
0.691 0.309 0.000
M23.8 Other internal derangements of knee
0.690 0.310 0.000
T51.0 Ethanol
0.690 0.310 0.000
G47.8 Other sleep disorders
0.689 0.311 0.000
G47.4 Narcolepsy and cataplexy
0.689 0.311 0.000
G47.2 Disorders of the sleep-wake schedule
0.689 0.311 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.689 0.311 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.689 0.311 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.689 0.311 0.000
K26 Duodenal ulcer
0.689 0.311 0.000
S88 Traumatic amputation of lower leg
0.687 0.313 0.000
S87 Crushing injury of lower leg
0.687 0.313 0.000
S86 Injury of muscle and tendon at lower leg level
0.687 0.313 0.000
S85 Injury of blood vessels at lower leg level
0.687 0.313 0.000
S84 Injury of nerves at lower leg level
0.687 0.313 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.686 0.314 0.000
V10-V19 Pedal cyclist injured in transport accident
0.684 0.316 0.000
S29 Other and unspecified injuries of thorax
0.683 0.317 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.682 0.317 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.682 0.317 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.682 0.317 0.000
G92 Toxic encephalopathy
0.682 0.317 0.000
M21.6 Other acquired deformities of ankle and foot
0.682 0.318 0.000
J94 Other pleural conditions
0.681 0.319 0.000
Chapter VIII Diseases of the ear and mastoid process
0.680 0.320 0.000
M15-M19 Arthrosis
0.680 0.320 0.000
S99 Other and unspecified injuries of ankle and foot
0.679 0.321 0.000
S98 Traumatic amputation of ankle and foot
0.679 0.321 0.000
S97 Crushing injury of ankle and foot
0.679 0.321 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.679 0.321 0.000
S95 Injury of blood vessels at ankle and foot level
0.679 0.321 0.000
S94 Injury of nerves at ankle and foot level
0.679 0.321 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.679 0.321 0.000
G95 Other diseases of spinal cord
0.679 0.321 0.000
K25 Gastric ulcer
0.679 0.321 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.679 0.321 0.000
J36 Peritonsillar abscess
0.678 0.321 0.000
M23.5 Chronic instability of knee
0.678 0.322 0.000
M23.1 Discoid meniscus (congenital)
0.678 0.322 0.000
M23.0 Cystic meniscus
0.678 0.322 0.000
M86-M90 Other osteopathies
0.678 0.322 0.000
H35.4 Peripheral retinal degeneration
0.677 0.323 0.000
J91 Pleural effusion in conditions classified elsewhere
0.677 0.323 0.000
M14 Arthropathies in other diseases classified elsewhere
0.676 0.324 0.000
M12 Other specific arthropathies
0.676 0.324 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.676 0.324 0.000
M08 Juvenile arthritis
0.676 0.324 0.000
Y40 Systemic antibiotics
0.674 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.674 0.325 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.673 0.327 0.000
G43 Migraine
0.673 0.327 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.673 0.327 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.673 0.327 0.000
T87 Complications peculiar to reattachment and amputation
0.672 0.328 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
K31 Other diseases of stomach and duodenum
0.672 0.328 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.672 0.328 0.000
J86 Pyothorax
0.671 0.329 0.000
J39.2 Other diseases of pharynx
0.670 0.330 0.000
K29.9 Gastroduodenitis, unspecified
0.669 0.331 0.000
K29.2 Alcoholic gastritis
0.669 0.331 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.668 0.331 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.668 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.668 0.332 0.000
T95 Sequelae of burns, corrosions and frostbite
0.668 0.332 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.668 0.332 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.668 0.332 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.668 0.332 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.668 0.332 0.000
K28 Gastrojejunal ulcer
0.668 0.332 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.668 0.332 0.000
J33.1 Polypoid sinus degeneration
0.667 0.333 0.000
H53.6 Night blindness
0.667 0.333 0.000
H53.5 Colour vision deficiencies
0.667 0.333 0.000
H53.3 Other disorders of binocular vision
0.667 0.333 0.000
G45.4 Transient global amnesia
0.665 0.335 0.000
K29.3 Chronic superficial gastritis
0.665 0.335 0.000
M47 Spondylosis
0.665 0.335 0.000
G96 Other disorders of central nervous system
0.665 0.335 0.000
G93.4 Encephalopathy, unspecified
0.664 0.336 0.000
J30 Vasomotor and allergic rhinitis
0.664 0.336 0.000
M50 Cervical disk disorders
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.336 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
H53.4 Visual field defects
0.663 0.337 0.000
S20 Superficial injury of thorax
0.663 0.337 0.000
B35-B49 Mycoses
0.662 0.338 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.661 0.338 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.661 0.338 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.661 0.338 0.000
T42.3 Barbiturates
0.661 0.338 0.000
T42.2 Succinimides and oxazolidinediones
0.661 0.338 0.000
T42.1 Iminostilbenes
0.661 0.338 0.000
T42.0 Hydantoin derivatives
0.661 0.338 0.000
B95-B98 Bacterial, viral and other infectious agents
0.661 0.339 0.000
S82.0 Fracture of patella
0.661 0.339 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.660 0.339 0.000
H10-H13 Disorders of conjunctiva
0.660 0.340 0.000
E65-E68 Obesity and other hyperalimentation
0.659 0.341 0.000
S22.3 Fracture of rib
0.659 0.341 0.000
M24.0 Loose body in joint
0.659 0.341 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.658 0.342 0.000
A00-A09 Intestinal infectious diseases
0.658 0.342 0.000
K29.1 Other acute gastritis
0.657 0.343 0.000
S82.10 Fracture of upper end of tibia (closed)
0.656 0.344 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.656 0.344 0.000
M21.3 Wrist or foot drop (acquired)
0.656 0.344 0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.656 0.344 0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.656 0.344 0.000
J35.2 Hypertrophy of adenoids
0.656 0.344 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.656 0.344 0.000
S32 Fracture of lumbar spine and pelvis
0.656 0.344 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.655 0.345 0.000
W06 Fall involving bed
0.655 0.345 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.654 0.346 0.000
S26 Injury of heart
0.654 0.346 0.000
S25 Injury of blood vessels of thorax
0.654 0.346 0.000
S24 Injury of nerves and spinal cord at thorax level
0.654 0.346 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.654 0.346 0.000
S21 Open wound of thorax
0.654 0.346 0.000
W29.9 Unspecified place
0.654 0.346 0.000
M20.3 Other deformity of hallux (acquired)
0.653 0.346 0.000
M35 Other systemic involvement of connective tissue
0.653 0.347 0.000
E11.5 With peripheral circulatory complications
0.652 0.348 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.652 0.348 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.652 0.348 0.000
T39.4 Antirheumatics, not elsewhere classified
0.652 0.348 0.000
T39.2 Pyrazolone derivatives
0.652 0.348 0.000
H36 Retinal disorders in diseases classified elsewhere
0.651 0.349 0.000
J31.2 Chronic pharyngitis
0.651 0.349 0.000
S91.0 Open wound of ankle
0.650 0.350 0.000
H31.8 Other specified disorders of choroid
0.650 0.350 0.000
K92.0 Haematemesis
0.649 0.351 0.000
H35.7 Separation of retinal layers
0.649 0.351 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.649 0.351 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.648 0.352 0.000
E46 Unspecified protein-energy malnutrition
0.647 0.352 0.000
T86 Failure and rejection of transplanted organs and tissues
0.647 0.353 0.000
E11.1 With ketoacidosis
0.646 0.354 0.000
T79.8 Other early complications of trauma
0.646 0.354 0.000
J32.8 Other chronic sinusitis
0.645 0.354 0.000
E14.3 With ophthalmic complications
0.644 0.356 0.000
H35.9 Retinal disorder, unspecified
0.643 0.357 0.000
W07 Fall involving chair
0.642 0.358 0.000
S82.5 Fracture of medial malleolus
0.642 0.358 0.000
M70-M79 Other soft tissue disorders
0.641 0.359 0.000
K38 Other diseases of appendix
0.640 0.360 0.000
S90.8 Other superficial injuries of ankle and foot
0.640 0.360 0.000
B99 Other and unspecified infectious diseases
0.639 0.360 0.000
H02.4 Ptosis of eyelid
0.639 0.361 0.000
M06.9 Rheumatoid arthritis, unspecified
0.638 0.362 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.638 0.362 0.000
S80.8 Other superficial injuries of lower leg
0.636 0.363 0.000
T92.0 Sequelae of open wound of upper limb
0.636 0.363 0.000
W19 Unspecified fall
0.636 0.364 0.000
M41.9 Scoliosis, unspecified
0.636 0.364 0.000
M05 Seropositive rheumatoid arthritis
0.635 0.364 0.000
K90 Intestinal malabsorption
0.635 0.365 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.634 0.365 0.000
K35.8 Acute appendicitis, other and unspecified
0.634 0.366 0.000
J17 Pneumonia in diseases classified elsewhere
0.633 0.366 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.633 0.366 0.000
J12 Viral pneumonia, not elsewhere classified
0.633 0.366 0.000
J11 Influenza, virus not identified
0.633 0.366 0.000
J09 Influenza due to certain identified influenza virus
0.633 0.366 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.633 0.367 0.000
J95-J99 Other diseases of the respiratory system
0.633 0.367 0.000
S91.3 Open wound of other parts of foot
0.632 0.368 0.000
S82.8 Fractures of other parts of lower leg
0.632 0.368 0.000
G93.7 Reye's syndrome
0.632 0.368 0.000
G93.6 Cerebral oedema
0.632 0.368 0.000
G93.5 Compression of brain
0.632 0.368 0.000
G93.2 Benign intracranial hypertension
0.632 0.368 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.632 0.368 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.631 0.369 0.000
M07 Psoriatic and enteropathic arthropathies
0.631 0.369 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.631 0.369 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.631 0.369 0.000
E15 Nondiabetic hypoglycaemic coma
0.631 0.369 0.000
M46 Other inflammatory spondylopathies
0.630 0.370 0.000
M24.1 Other articular cartilage disorders
0.629 0.371 0.000
W44 Foreign body entering into or through eye or natural orifice
0.629 0.371 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.629 0.371 0.000
M48 Other spondylopathies
0.628 0.372 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.628 0.372 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.627 0.372 0.000
H30 Chorioretinal inflammation
0.627 0.372 0.000
H54.9 Unspecified visual impairment (binocular)
0.627 0.373 0.000
M06.0 Seronegative rheumatoid arthritis
0.627 0.373 0.000
M23.4 Loose body in knee
0.625 0.374 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.625 0.374 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.625 0.374 0.000
Y98 Lifestyle-related condition
0.625 0.374 0.000
Y97 Environmental-pollution-related condition
0.625 0.374 0.000
Y96 Work-related condition
0.625 0.374 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.625 0.375 0.000
Y45.2 Propionic acid derivatives
0.624 0.376 0.000
T40.2 Other opioids
0.624 0.376 0.000
G97.8 Other postprocedural disorders of nervous system
0.623 0.377 0.000
S27.3 Other injuries of lung
0.622 0.377 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.622 0.378 0.000
H54.6 Unqualified visual loss, one eye
0.622 0.378 0.000
H54.5 Low vision, one eye
0.622 0.378 0.000
H54.3 Unqualified visual loss, both eyes
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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