TreeWAS – Variant ID: rs74850627

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
J40-J47 Chronic lower respiratory diseases	0.999	0.001
Chapter VII Diseases of the eye and adnexa	0.999	0.001
Chapter VIII Diseases of the ear and mastoid process	0.997	0.003
Chapter II Neoplasms	0.997	0.003
J44 Other chronic obstructive pulmonary disease	0.995	0.005
H25-H28 Disorders of lens	0.995	0.005
J30-J39 Other diseases of upper respiratory tract	0.993	0.007
M50-M54 Other dorsopathies	0.992	0.008
S60-S69 Injuries to the wrist and hand	0.991	0.009
H65-H75 Diseases of middle ear and mastoid	0.987	0.013
J33 Nasal polyp	0.978	0.022
M54 Dorsalgia	0.978	0.022
C15-C26 Malignant neoplasms of digestive organs	0.977	0.023
H26 Other cataract	0.976	0.024
J90-J94 Other diseases of pleura	0.973	0.027
H26.9 Cataract, unspecified	0.968	0.032
D10-D36 Benign neoplasms	0.968	0.032
J34 Other disorders of nose and nasal sinuses	0.959	0.041
J33.9 Nasal polyp, unspecified	0.955	0.045
J90 Pleural effusion, not elsewhere classified	0.950	0.050
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.950	0.050
H25 Senile cataract	0.949	0.051
Chapter VI Diseases of the nervous system	0.946	0.054
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.946	0.054
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.938	0.062
H71 Cholesteatoma of middle ear	0.936	0.064
H90-H95 Other disorders of ear	0.933	0.067
J40 Bronchitis, not specified as acute or chronic	0.931	0.069
M54.1 Radiculopathy	0.928	0.072
S70-S79 Injuries to the hip and thigh	0.926	0.074
T66-T78 Other and unspecified effects of external causes	0.921	0.079
M15-M19 Arthrosis	0.920	0.080
C18 Malignant neoplasm of colon	0.919	0.081
S61 Open wound of wrist and hand	0.918	0.082
S80-S89 Injuries to the knee and lower leg	0.914	0.086
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.913	0.087
H65 Nonsuppurative otitis media	0.909	0.091
D22 Melanocytic naevi	0.906	0.094
Chapter XX External causes of morbidity and mortality	0.906	0.094
H25.1 Senile nuclear cataract	0.905	0.095
C34 Malignant neoplasm of bronchus and lung	0.901	0.099
S66 Injury of muscle and tendon at wrist and hand level	0.898	0.102
S62 Fracture at wrist and hand level	0.896	0.104
J43 Emphysema	0.896	0.104
J44.8 Other specified chronic obstructive pulmonary disease	0.895	0.105
S90-S99 Injuries to the ankle and foot	0.895	0.105
C19 Malignant neoplasm of rectosigmoid junction	0.894	0.105
G90-G99 Other disorders of the nervous system	0.886	0.114
H25.9 Senile cataract, unspecified	0.885	0.115
M70-M79 Other soft tissue disorders	0.877	0.123
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.877	0.123
M54.5 Low back pain	0.874	0.126
C34.1 Upper lobe, bronchus or lung	0.873	0.127
J95-J99 Other diseases of the respiratory system	0.869	0.131
D00-D09 In situ neoplasms	0.868	0.132
M17 Gonarthrosis [arthrosis of knee]	0.867	0.133
S72 Fracture of femur	0.867	0.133
T78 Adverse effects, not elsewhere classified	0.865	0.135
M20-M25 Other joint disorders	0.865	0.135
S82 Fracture of lower leg, including ankle	0.857	0.143
J34.2 Deviated nasal septum	0.856	0.144
H43-H45 Disorders of vitreous body and globe	0.853	0.147
D22.7 Melanocytic naevi of lower limb, including hip	0.853	0.147
H92 Otalgia and effusion of ear	0.852	0.148
D23 Other benign neoplasms of skin	0.851	0.149
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.849	0.151
M54.9 Dorsalgia, unspecified	0.848	0.152
M17.9 Gonarthrosis, unspecified	0.845	0.155
G70-G73 Diseases of myoneural junction and muscle	0.845	0.155
C25 Malignant neoplasm of pancreas	0.844	0.156
T36-T50 Poisoning by drugs, medicaments and biological substances	0.840	0.160
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.840	0.160
M50 Cervical disk disorders	0.839	0.161
M22 Disorders of patella	0.839	0.161
M65-M68 Disorders of synovium and tendon	0.839	0.161
M80-M85 Disorders of bone density and structure	0.836	0.164
J34.8 Other specified disorders of nose and nasal sinuses	0.835	0.165
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.832	0.167
M91-M94 Chondropathies	0.832	0.168
T79-T79 Certain early complications of trauma	0.829	0.171
D13.1 Stomach	0.827	0.173
S64 Injury of nerves at wrist and hand level	0.824	0.176
M54.59 Low back pain (Site unspecified)	0.823	0.177
S10-S19 Injuries to the neck	0.823	0.177
M54.16 Radiculopathy (Lumbar region)	0.823	0.177
J43.9 Emphysema, unspecified	0.822	0.178
G50-G59 Nerve, nerve root and plexus disorders	0.820	0.180
D21 Other benign neoplasms of connective and other soft tissue	0.819	0.181
Chapter XXII Codes for special purposes	0.816	0.184
H66 Suppurative and unspecified otitis media	0.815	0.185
J33.0 Polyp of nasal cavity	0.815	0.185
H55-H59 Other disorders of eye and adnexa	0.814	0.186
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.811	0.189
H69 Other disorders of Eustachian tube	0.805	0.195
M22.4 Chondromalacia patellae	0.804	0.196
S61.1 Open wound of finger(s) with damage to nail	0.803	0.197
J94 Other pleural conditions	0.801	0.199
S92 Fracture of foot, except ankle	0.797	0.203
M45-M49 Spondylopathies	0.797	0.203
D32 Benign neoplasm of meninges	0.797	0.203
M54.12 Radiculopathy (Cervical region)	0.797	0.203
D37-D48 Neoplasms of uncertain or unknown behaviour	0.795	0.205
D28 Benign neoplasm of other and unspecified female genital organs	0.795	0.205
J34.3 Hypertrophy of nasal turbinates	0.794	0.206
C18.6 Descending colon	0.793	0.207
D23.3 Skin of other and unspecified parts of face	0.791	0.209
G99 Other disorders of nervous system in diseases classified elsewhere	0.791	0.209
M05-M14 Inflammatory polyarthropathies	0.788	0.211
T78.3 Angioneurotic oedema	0.788	0.212
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.786	0.214
M71 Other bursopathies	0.785	0.215
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.785	0.215
H92.1 Otorrhoea	0.783	0.217
S50-S59 Injuries to the elbow and forearm	0.782	0.218
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.780	0.220
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.780	0.220
S72.0 Fracture of neck of femur	0.778	0.222
M51 Other intervertebral disk disorders	0.778	0.222
H90 Conductive and sensorineural hearing loss	0.777	0.222
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.776	0.224
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.776	0.224
H30-H36 Disorders of choroid and retina	0.775	0.224
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.775	0.225
H65.9 Nonsuppurative otitis media, unspecified	0.773	0.227
H10-H13 Disorders of conjunctiva	0.772	0.228
M24 Other specific joint derangements	0.771	0.229
C18.7 Sigmoid colon	0.770	0.230
S82.8 Fractures of other parts of lower leg	0.770	0.230
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.770	0.230
D34 Benign neoplasm of thyroid gland	0.767	0.233
H74 Other disorders of middle ear and mastoid	0.765	0.235
J98 Other respiratory disorders	0.765	0.235
H46-H48 Disorders of optic nerve and visual pathways	0.764	0.236
M79 Other soft tissue disorders, not elsewhere classified	0.762	0.238
S40-S49 Injuries to the shoulder and upper arm	0.762	0.238
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.762	0.238
D22.6 Melanocytic naevi of upper limb, including shoulder	0.762	0.238
J44.9 Chronic obstructive pulmonary disease, unspecified	0.762	0.238
T91 Sequelae of injuries of neck and trunk	0.760	0.240
H65.3 Chronic mucoid otitis media	0.760	0.240
J33.8 Other polyp of sinus	0.757	0.243
G80-G83 Cerebral palsy and other paralytic syndromes	0.757	0.243
S61.7 Multiple open wounds of wrist and hand	0.756	0.244
S82.1 Fracture of upper end of tibia	0.754	0.246
G70 Myasthenia gravis and other myoneural disorders	0.753	0.247
M54.17 Radiculopathy (Lumbosacral region)	0.752	0.248
T15-T19 Effects of foreign body entering through natural orifice	0.752	0.248
C26 Malignant neoplasm of other and ill-defined digestive organs	0.751	0.249
C18.0 Caecum	0.750	0.250
M54.3 Sciatica	0.748	0.251
C25.9 Pancreas, unspecified	0.748	0.252
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.748	0.252
H53-H54 Visual disturbances and blindness	0.747	0.253
S62.3 Fracture of other metacarpal bone	0.744	0.255
T90 Sequelae of injuries of head	0.741	0.258
T93 Sequelae of injuries of lower limb	0.741	0.259
W00-W19 Falls	0.738	0.262
D07 Carcinoma in situ of other and unspecified genital organs	0.738	0.262
J46 Status asthmaticus	0.735	0.265
S61.9 Open wound of wrist and hand, part unspecified	0.735	0.265
M65 Synovitis and tenosynovitis	0.734	0.266
M50.0 Cervical disk disorder with myelopathy	0.731	0.269
M18 Arthrosis of first carpometacarpal joint	0.728	0.272
C97 Malignant neoplasms of independent (primary) multiple sites	0.728	0.272
H60-H62 Diseases of external ear	0.728	0.272
S79 Other and unspecified injuries of hip and thigh	0.727	0.273
J80-J84 Other respiratory diseases principally affecting the interstitium	0.726	0.274
C32 Malignant neoplasm of larynx	0.726	0.274
M54.6 Pain in thoracic spine	0.725	0.275
H43 Disorders of vitreous body	0.725	0.275
H65.2 Chronic serous otitis media	0.724	0.276
D17 Benign lipomatous neoplasm	0.723	0.277
G99.2 Myelopathy in diseases classified elsewhere	0.722	0.278
D03 Melanoma in situ	0.722	0.278
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.721	0.278
J91 Pleural effusion in conditions classified elsewhere	0.721	0.279
J20-J22 Other acute lower respiratory infections	0.721	0.279
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.720	0.280
M71.2 Synovial cyst of popliteal space [Baker]	0.720	0.280
S67 Crushing injury of wrist and hand	0.719	0.281
D22.4 Melanocytic naevi of scalp and neck	0.719	0.281
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.719	0.281
M48 Other spondylopathies	0.719	0.281
S61.0 Open wound of finger(s) without damage to nail	0.719	0.281
G93 Other disorders of brain	0.718	0.282
C18.4 Transverse colon	0.717	0.282
J34.0 Abscess, furuncle and carbuncle of nose	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
S92.0 Fracture of calcaneus	0.717	0.283
S68 Traumatic amputation of wrist and hand	0.716	0.284
M00-M03 Infectious arthropathies	0.716	0.284
J41 Simple and mucopurulent chronic bronchitis	0.716	0.284
D26 Other benign neoplasms of uterus	0.715	0.284
S72.00 Fracture of neck of femur (closed)	0.715	0.285
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.285
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.714	0.286
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.713	0.287
H27 Other disorders of lens	0.713	0.287
D21.2 Connective and other soft tissue of lower limb, including hip	0.713	0.287
S72.2 Subtrochanteric fracture	0.713	0.287
J37 Chronic laryngitis and laryngotracheitis	0.712	0.288
M53 Other dorsopathies, not elsewhere classified	0.711	0.289
S65 Injury of blood vessels at wrist and hand level	0.711	0.289
G95 Other diseases of spinal cord	0.710	0.290
J42 Unspecified chronic bronchitis	0.710	0.290
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.710	0.290
S82.80 Fractures of other parts of lower leg (closed)	0.708	0.292
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.708	0.292
H70 Mastoiditis and related conditions	0.708	0.292
H68 Eustachian salpingitis and obstruction	0.708	0.292
H67 Otitis media in diseases classified elsewhere	0.708	0.292
D06 Carcinoma in situ of cervix uteri	0.707	0.293
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.707	0.293
T79 Certain early complications of trauma, not elsewhere classified	0.707	0.293
S69 Other and unspecified injuries of wrist and hand	0.706	0.294
S62.8 Fracture of other and unspecified parts of wrist and hand	0.706	0.294
J38.4 Oedema of larynx	0.704	0.296
J34.1 Cyst and mucocele of nose and nasal sinus	0.704	0.296
S64.4 Injury of digital nerve of other finger	0.704	0.296
J33.1 Polypoid sinus degeneration	0.701	0.299
M54.8 Other dorsalgia	0.701	0.299
M54.0 Panniculitis affecting regions of neck and back	0.701	0.299
M54.96 Dorsalgia, unspecified (Lumbar region)	0.701	0.299
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.701	0.299
T43.2 Other and unspecified antidepressants	0.701	0.299
S66.8 Injury of other muscles and tendons at wrist and hand level	0.700	0.300
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.700	0.300
C21 Malignant neoplasm of anus and anal canal	0.700	0.300
C17 Malignant neoplasm of small intestine	0.700	0.300
C23 Malignant neoplasm of gallbladder	0.700	0.300
H26.3 Drug-induced cataract	0.700	0.300
H26.2 Complicated cataract	0.700	0.300
H26.1 Traumatic cataract	0.700	0.300
H26.0 Infantile, juvenile and presenile cataract	0.700	0.300
S90 Superficial injury of ankle and foot	0.700	0.300
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.699	0.301
J93 Pneumothorax	0.698	0.302
S72.1 Pertrochanteric fracture	0.697	0.302
S62.6 Fracture of other finger	0.697	0.303
M40-M43 Deforming dorsopathies	0.696	0.304
J09-J18 Influenza and pneumonia	0.696	0.304
G58 Other mononeuropathies	0.694	0.305
D31 Benign neoplasm of eye and adnexa	0.694	0.306
D30 Benign neoplasm of urinary organs	0.694	0.306
D29 Benign neoplasm of male genital organs	0.694	0.306
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.694	0.306
D19 Benign neoplasm of mesothelial tissue	0.694	0.306
D16 Benign neoplasm of bone and articular cartilage	0.694	0.306
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.694	0.306
D14 Benign neoplasm of middle ear and respiratory system	0.694	0.306
H66.9 Otitis media, unspecified	0.693	0.307
J47 Bronchiectasis	0.692	0.308
M54.94 Dorsalgia, unspecified (Thoracic region)	0.691	0.309
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.691	0.309
M86-M90 Other osteopathies	0.691	0.309
M54.57 Low back pain (Lumbosacral region)	0.690	0.310
D18 Haemangioma and lymphangioma, any site	0.689	0.310
S62.2 Fracture of first metacarpal bone	0.689	0.311
H73 Other disorders of tympanic membrane	0.688	0.312
G70.0 Myasthenia gravis	0.687	0.312
X40-X49 Accidental poisoning by and exposure to noxious substances	0.687	0.313
V20-V29 Motorcycle rider injured in transport accident	0.687	0.313
D25 Leiomyoma of uterus	0.687	0.313
T78.0 Anaphylactic shock due to adverse food reaction	0.686	0.314
D23.2 Skin of ear and external auricular canal	0.685	0.315
D35 Benign neoplasm of other and unspecified endocrine glands	0.685	0.315
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.684	0.315
M54.4 Lumbago with sciatica	0.684	0.316
M22.8 Other disorders of patella	0.682	0.318
H25.2 Senile cataract, morgagnian type	0.681	0.319
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.681	0.319
Chapter IX Diseases of the circulatory system	0.680	0.320
S82.10 Fracture of upper end of tibia (closed)	0.679	0.321
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.678	0.322
C38 Malignant neoplasm of heart, mediastinum and pleura	0.678	0.322
C31 Malignant neoplasm of accessory sinuses	0.678	0.322
C30 Malignant neoplasm of nasal cavity and middle ear	0.678	0.322
C37 Malignant neoplasm of thymus	0.678	0.322
C33 Malignant neoplasm of trachea	0.678	0.322
T92 Sequelae of injuries of upper limb	0.678	0.322
J94.8 Other specified pleural conditions	0.678	0.322
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.677	0.323
J30 Vasomotor and allergic rhinitis	0.677	0.323
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.677	0.323
Y60-Y69 Misadventures to patients during surgical and medical care	0.676	0.324
D24 Benign neoplasm of breast	0.676	0.324
H69.9 Eustachian tube disorder, unspecified	0.675	0.325
T31 Burns classified according to extent of body surface involved	0.675	0.325
J60-J70 Lung diseases due to external agents	0.675	0.325
D32.0 Cerebral meninges	0.675	0.325
G00-G09 Inflammatory diseases of the central nervous system	0.674	0.326
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.673	0.327
H25.8 Other senile cataract	0.673	0.327
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.673	0.327
H91 Other hearing loss	0.673	0.327
M50.2 Other cervical disk displacement	0.673	0.327
H80-H83 Diseases of inner ear	0.673	0.327
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.672	0.328
T78.4 Allergy, unspecified	0.672	0.328
M92 Other juvenile osteochondrosis	0.671	0.329
D28.0 Vulva	0.671	0.329
D22.2 Melanocytic naevi of ear and external auricular canal	0.670	0.330
M80 Osteoporosis with pathological fracture	0.670	0.330
H94 Other disorders of ear in diseases classified elsewhere	0.669	0.331
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.669	0.331
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.669	0.331
C34.0 Main bronchus	0.668	0.332
C18.5 Splenic flexure	0.667	0.333
X20-X29 Contact with venomous animals and plants	0.666	0.333
S82.4 Fracture of fibula alone	0.666	0.334
M54.19 Radiculopathy (Site unspecified)	0.666	0.334
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.666	0.334
M54.15 Radiculopathy (Thoracolumbar region)	0.666	0.334
M54.14 Radiculopathy (Thoracic region)	0.666	0.334
M54.13 Radiculopathy (Cervicothoracic region)	0.666	0.334
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.666	0.334
M54.10 Radiculopathy (Multiple sites in spine)	0.666	0.334
S12 Fracture of neck	0.665	0.335
I60-I69 Cerebrovascular diseases	0.665	0.335
D17.6 Benign lipomatous neoplasm of spermatic cord	0.664	0.336
S78 Traumatic amputation of hip and thigh	0.664	0.336
S77 Crushing injury of hip and thigh	0.664	0.336
S76 Injury of muscle and tendon at hip and thigh level	0.664	0.336
S75 Injury of blood vessels at hip and thigh level	0.664	0.336
S74 Injury of nerves at hip and thigh level	0.664	0.336
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.664	0.336
S71 Open wound of hip and thigh	0.664	0.336
H26.8 Other specified cataract	0.663	0.336
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.662	0.338
C18.9 Colon, unspecified	0.661	0.339
M06 Other rheumatoid arthritis	0.661	0.339
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.661	0.339
T75 Effects of other external causes	0.661	0.339
T74 Maltreatment syndromes	0.661	0.339
T73 Effects of other deprivation	0.661	0.339
T70 Effects of air pressure and water pressure	0.661	0.339
T69 Other effects of reduced temperature	0.661	0.339
T67 Effects of heat and light	0.661	0.339
T71 Asphyxiation	0.661	0.339
T68 Hypothermia	0.661	0.339
T66 Unspecified effects of radiation	0.661	0.339
S00-S09 Injuries to the head	0.660	0.340
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.660	0.340
M15 Polyarthrosis	0.659	0.341
S92.00 Fracture of calcaneus (closed)	0.659	0.341
C18.8 Overlapping lesion of colon	0.659	0.341
C18.1 Appendix	0.659	0.341
D23.5 Skin of trunk	0.659	0.341
S62.5 Fracture of thumb	0.659	0.341
M17.1 Other primary gonarthrosis	0.658	0.342
M77 Other enthesopathies	0.658	0.342
H44 Disorders of globe	0.658	0.342
S60 Superficial injury of wrist and hand	0.656	0.343
G71 Primary disorders of muscles	0.656	0.344
C34.9 Bronchus or lung, unspecified	0.656	0.344
S88 Traumatic amputation of lower leg	0.655	0.345
S87 Crushing injury of lower leg	0.655	0.345
S86 Injury of muscle and tendon at lower leg level	0.655	0.345
S85 Injury of blood vessels at lower leg level	0.655	0.345
S84 Injury of nerves at lower leg level	0.655	0.345
M94 Other disorders of cartilage	0.655	0.345
T98 Sequelae of other and unspecified effects of external causes	0.655	0.345
T95 Sequelae of burns, corrosions and frostbite	0.655	0.345
T94 Sequelae of injuries involving multiple and unspecified body regions	0.655	0.345
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.655	0.345
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.655	0.345
Chapter I Certain infectious and parasitic diseases	0.653	0.347
G91 Hydrocephalus	0.652	0.348
H65.4 Other chronic nonsuppurative otitis media	0.651	0.348
H65.1 Other acute nonsuppurative otitis media	0.651	0.348
H65.0 Acute serous otitis media	0.651	0.348
M22.2 Patellofemoral disorders	0.651	0.349
T91.3 Sequelae of injury of spinal cord	0.650	0.350
D33 Benign neoplasm of brain and other parts of central nervous system	0.650	0.350
D22.9 Melanocytic naevi, unspecified	0.650	0.350
Y35-Y36 Legal intervention and operations of war	0.650	0.350
Y10-Y34 Event of undetermined intent	0.650	0.350
Y00-Y09 Assault	0.650	0.350
X85-X99 Assault	0.650	0.350
X58-X59 Accidental exposure to other and unspecified factors	0.650	0.350
X50-X57 Overexertion, travel and privation	0.650	0.350
X30-X39 Exposure to forces of nature	0.650	0.350
X10-X19 Contact with heat and hot substances	0.650	0.350
X00-X09 Exposure to smoke, fire and flames	0.650	0.350
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.650	0.350
W75-W84 Other accidental threats to breathing	0.650	0.350
W65-W74 Accidental drowning and submersion	0.650	0.350
W50-W64 Exposure to animate mechanical forces	0.650	0.350
V98-V99 Other and unspecified transport accidents	0.650	0.350
V95-V97 Air and space transport accidents	0.650	0.350
V90-V94 Water transport accidents	0.650	0.350
V80-V89 Other land transport accidents	0.650	0.350
V70-V79 Bus occupant injured in transport accident	0.650	0.350
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.650	0.350
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.650	0.350
V40-V49 Car occupant injured in transport accident	0.650	0.350
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.650	0.350
V01-V09 Pedestrian injured in transport accident	0.650	0.350
H92.0 Otalgia	0.649	0.351
W07 Fall involving chair	0.649	0.351
J95 Postprocedural respiratory disorders, not elsewhere classified	0.648	0.352
Y57 Other and unspecified drugs and medicaments	0.647	0.353
J32 Chronic sinusitis	0.647	0.353
D22.1 Melanocytic naevi of eyelid, including canthus	0.647	0.353
C34.8 Overlapping lesion of bronchus and lung	0.646	0.354
C34.2 Middle lobe, bronchus or lung	0.646	0.354
J38.7 Other diseases of larynx	0.645	0.355
M84 Disorders of continuity of bone	0.645	0.355
J98.4 Other disorders of lung	0.645	0.355
D07.5 Prostate	0.644	0.356
T78.2 Anaphylactic shock, unspecified	0.644	0.356
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.644	0.356
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.644	0.356
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.644	0.356
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.644	0.356
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.644	0.356
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.644	0.356
V10-V19 Pedal cyclist injured in transport accident	0.643	0.357
M51.8 Other specified intervertebral disk disorders	0.643	0.357
S62.7 Multiple fractures of fingers	0.642	0.357
S62.4 Multiple fractures of metacarpal bones	0.642	0.357
S62.1 Fracture of other carpal bone(s)	0.642	0.357
S62.0 Fracture of navicular [scaphoid] bone of hand	0.642	0.357
J43.8 Other emphysema	0.642	0.358
J43.2 Centrilobular emphysema	0.642	0.358
J43.1 Panlobular emphysema	0.642	0.358
J43.0 MacLeod's syndrome	0.642	0.358
S99 Other and unspecified injuries of ankle and foot	0.642	0.358
S98 Traumatic amputation of ankle and foot	0.642	0.358
S97 Crushing injury of ankle and foot	0.642	0.358
S96 Injury of muscle and tendon at ankle and foot level	0.642	0.358
S95 Injury of blood vessels at ankle and foot level	0.642	0.358
S94 Injury of nerves at ankle and foot level	0.642	0.358
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.642	0.358
S91 Open wound of ankle and foot	0.642	0.358
J38.2 Nodules of vocal cords	0.642	0.358
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.641	0.359
D04 Carcinoma in situ of skin	0.641	0.359
H55 Nystagmus and other irregular eye movements	0.641	0.359
J38.1 Polyp of vocal cord and larynx	0.641	0.359
J98.9 Respiratory disorder, unspecified	0.640	0.360
G20-G26 Extrapyramidal and movement disorders	0.639	0.360
H53 Visual disturbances	0.639	0.361
G56 Mononeuropathies of upper limb	0.639	0.361
X60-X84 Intentional self-harm	0.638	0.362
C18.2 Ascending colon	0.638	0.362
C18.3 Hepatic flexure	0.637	0.363
S62.30 Fracture of other metacarpal bone (closed)	0.636	0.364
J31.0 Chronic rhinitis	0.635	0.364
D36 Benign neoplasm of other and unspecified sites	0.635	0.365
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.635	0.365
G94 Other disorders of brain in diseases classified elsewhere	0.635	0.365
G90 Disorders of autonomic nervous system	0.635	0.365
G98 Other disorders of nervous system, not elsewhere classified	0.635	0.365
G92 Toxic encephalopathy	0.635	0.365
S19 Other and unspecified injuries of neck	0.635	0.365
S82.2 Fracture of shaft of tibia	0.635	0.365
C16 Malignant neoplasm of stomach	0.634	0.366
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.633	0.367
M79.1 Myalgia	0.633	0.367
G50 Disorders of trigeminal nerve	0.632	0.367
H43.8 Other disorders of vitreous body	0.632	0.368
W20-W49 Exposure to inanimate mechanical forces	0.631	0.368
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.631	0.369
H57 Other disorders of eye and adnexa	0.631	0.369
M65.3 Trigger finger	0.631	0.369
M05 Seropositive rheumatoid arthritis	0.630	0.370
M48.0 Spinal stenosis	0.630	0.370
I69 Sequelae of cerebrovascular disease	0.629	0.371
M76 Enthesopathies of lower limb, excluding foot	0.629	0.371
M73 Soft tissue disorders in diseases classified elsewhere	0.629	0.371
D13.9 Ill-defined sites within the digestive system	0.629	0.371
D13.7 Endocrine pancreas	0.629	0.371
D13.6 Pancreas	0.629	0.371
D13.5 Extrahepatic bile ducts	0.629	0.371
D13.4 Liver	0.629	0.371
D13.3 Other and unspecified parts of small intestine	0.629	0.371
D13.0 Oesophagus	0.629	0.371
I63 Cerebral infarction	0.628	0.372
G54 Nerve root and plexus disorders	0.627	0.373
M54.55 Low back pain (Thoracolumbar region)	0.627	0.373
M54.54 Low back pain-Thoracic	0.627	0.373
M54.53 Low back pain-Cervicothoracic	0.627	0.373
M54.52 Low back pain-Cervical	0.627	0.373
M54.51 Low back pain-Occipit-atl-axl	0.627	0.373
M54.50 Low back pain (Multiple sites in spine)	0.627	0.373
M81 Osteoporosis without pathological fracture	0.627	0.373
M25 Other joint disorders, not elsewhere classified	0.627	0.373
D25.0 Submucous leiomyoma of uterus	0.626	0.374
H31 Other disorders of choroid	0.626	0.374
H36 Retinal disorders in diseases classified elsewhere	0.625	0.375

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations