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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74910874
log Bayes Factor = 2.61067
Chromosome 12   position 67,086,810  (GRCh37) Explore rs74910874 on Ensembl!
Variant rs74910874 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.961 0.039 0.000
Chapter XIV Diseases of the genitourinary system
0.946 0.054 0.000
Chapter X Diseases of the respiratory system
0.940 0.060 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.931 0.069 0.000
Chapter V Mental and behavioural disorders
0.930 0.070 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.899 0.101 0.000
H25-H28 Disorders of lens
0.890 0.110 0.000
Chapter VI Diseases of the nervous system
0.890 0.110 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.884 0.116 0.000
M70-M79 Other soft tissue disorders
0.872 0.128 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.867 0.133 0.000
N30-N39 Other diseases of urinary system
0.866 0.134 0.000
Chapter I Certain infectious and parasitic diseases
0.857 0.143 0.000
O60-O75 Complications of labour and delivery
0.855 0.145 0.000
O80-O84 Delivery
0.847 0.153 0.000
H30-H36 Disorders of choroid and retina
0.845 0.155 0.000
S80-S89 Injuries to the knee and lower leg
0.844 0.156 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.820 0.180 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.819 0.181 0.000
J30-J39 Other diseases of upper respiratory tract
0.819 0.181 0.000
S60-S69 Injuries to the wrist and hand
0.818 0.182 0.000
M75 Shoulder lesions
0.816 0.184 0.000
M20-M25 Other joint disorders
0.810 0.190 0.000
S00-S09 Injuries to the head
0.808 0.192 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.806 0.194 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.803 0.197 0.000
H25 Senile cataract
0.794 0.206 0.000
F30-F39 Mood [affective] disorders
0.794 0.206 0.000
J90-J94 Other diseases of pleura
0.792 0.207 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.791 0.209 0.000
Chapter XX External causes of morbidity and mortality
0.788 0.212 0.000
N60-N64 Disorders of breast
0.786 0.214 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.774 0.226 0.000
J20-J22 Other acute lower respiratory infections
0.768 0.232 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.766 0.234 0.000
M23 Internal derangement of knee
0.759 0.241 0.000
T66-T78 Other and unspecified effects of external causes
0.758 0.242 0.000
N40-N51 Diseases of male genital organs
0.757 0.243 0.000
H26 Other cataract
0.757 0.243 0.000
H33 Retinal detachments and breaks
0.756 0.244 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.754 0.246 0.000
O80 Single spontaneous delivery
0.753 0.247 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.740 0.260 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.736 0.264 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.730 0.270 0.000
L60-L75 Disorders of skin appendages
0.730 0.270 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.730 0.270 0.000
S20-S29 Injuries to the thorax
0.729 0.271 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.728 0.272 0.000
H53-H54 Visual disturbances and blindness
0.727 0.273 0.000
M75.4 Impingement syndrome of shoulder
0.725 0.275 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.722 0.278 0.000
J00-J06 Acute upper respiratory infections
0.722 0.278 0.000
G40-G47 Episodic and paroxysmal disorders
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.720 0.280 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.717 0.283 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.715 0.285 0.000
S40-S49 Injuries to the shoulder and upper arm
0.715 0.285 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.715 0.285 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.715 0.285 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.713 0.287 0.000
N30 Cystitis
0.713 0.287 0.000
N00-N08 Glomerular diseases
0.711 0.288 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.710 0.290 0.000
N10-N16 Renal tubulo-interstitial diseases
0.710 0.290 0.000
O42 Premature rupture of membranes
0.709 0.291 0.000
N39 Other disorders of urinary system
0.709 0.291 0.000
J33 Nasal polyp
0.708 0.292 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.706 0.294 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
S90-S99 Injuries to the ankle and foot
0.704 0.296 0.000
S10-S19 Injuries to the neck
0.704 0.296 0.000
L40-L45 Papulosquamous disorders
0.702 0.298 0.000
O85-O92 Complications predominantly related to the puerperium
0.701 0.299 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.701 0.299 0.000
S70-S79 Injuries to the hip and thigh
0.697 0.302 0.000
N25-N29 Other disorders of kidney and ureter
0.696 0.304 0.000
N87 Dysplasia of cervix uteri
0.695 0.305 0.000
A30-A49 Other bacterial diseases
0.695 0.305 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.694 0.305 0.000
G30-G32 Other degenerative diseases of the nervous system
0.694 0.306 0.000
N35 Urethral stricture
0.694 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.694 0.306 0.000
F31 Bipolar affective disorder
0.694 0.306 0.000
H25.1 Senile nuclear cataract
0.692 0.308 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.691 0.309 0.000
H26.9 Cataract, unspecified
0.690 0.310 0.000
N99-N99 Other disorders of the genitourinary system
0.690 0.310 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.689 0.310 0.000
S50-S59 Injuries to the elbow and forearm
0.689 0.311 0.000
H55-H59 Other disorders of eye and adnexa
0.689 0.311 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.689 0.311 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.689 0.311 0.000
M40-M43 Deforming dorsopathies
0.688 0.312 0.000
O80.0 Spontaneous vertex delivery
0.686 0.314 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.686 0.314 0.000
B25-B34 Other viral diseases
0.685 0.315 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.684 0.316 0.000
O00-O08 Pregnancy with abortive outcome
0.681 0.319 0.000
M65-M68 Disorders of synovium and tendon
0.680 0.320 0.000
H43-H45 Disorders of vitreous body and globe
0.679 0.320 0.000
J60-J70 Lung diseases due to external agents
0.679 0.321 0.000
M45-M49 Spondylopathies
0.678 0.322 0.000
Chapter VIII Diseases of the ear and mastoid process
0.677 0.323 0.000
O47 False labour
0.677 0.323 0.000
J95-J99 Other diseases of the respiratory system
0.676 0.324 0.000
M75.1 Rotator cuff syndrome
0.676 0.324 0.000
J93 Pneumothorax
0.676 0.324 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
M91-M94 Chondropathies
0.668 0.332 0.000
M86-M90 Other osteopathies
0.668 0.332 0.000
M60-M63 Disorders of muscles
0.668 0.332 0.000
M00-M03 Infectious arthropathies
0.668 0.332 0.000
M80-M85 Disorders of bone density and structure
0.668 0.332 0.000
S81 Open wound of lower leg
0.668 0.332 0.000
E70-E90 Metabolic disorders
0.668 0.332 0.000
F99-F99 Unspecified mental disorder
0.667 0.333 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.667 0.333 0.000
F80-F89 Disorders of psychological development
0.667 0.333 0.000
F70-F79 Mental retardation
0.667 0.333 0.000
F60-F69 Disorders of adult personality and behaviour
0.667 0.333 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.667 0.333 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.667 0.333 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.665 0.335 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.665 0.335 0.000
O70 Perineal laceration during delivery
0.665 0.335 0.000
G93 Other disorders of brain
0.664 0.336 0.000
H25.8 Other senile cataract
0.661 0.339 0.000
H01 Other inflammation of eyelid
0.658 0.342 0.000
S61 Open wound of wrist and hand
0.658 0.342 0.000
N32 Other disorders of bladder
0.658 0.342 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.656 0.344 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.655 0.345 0.000
E65-E68 Obesity and other hyperalimentation
0.654 0.345 0.000
O36 Maternal care for other known or suspected foetal problems
0.653 0.347 0.000
N81 Female genital prolapse
0.653 0.347 0.000
O20 Haemorrhage in early pregnancy
0.651 0.349 0.000
S80 Superficial injury of lower leg
0.651 0.349 0.000
H36 Retinal disorders in diseases classified elsewhere
0.649 0.351 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.649 0.351 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.648 0.352 0.000
H33.0 Retinal detachment with retinal break
0.648 0.352 0.000
S00 Superficial injury of head
0.648 0.352 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.648 0.352 0.000
M75.0 Adhesive capsulitis of shoulder
0.647 0.353 0.000
E50-E64 Other nutritional deficiencies
0.645 0.354 0.000
B95-B98 Bacterial, viral and other infectious agents
0.645 0.355 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.645 0.355 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.645 0.355 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.645 0.355 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.645 0.355 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.645 0.355 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.645 0.355 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.645 0.355 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.645 0.355 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.645 0.355 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.645 0.355 0.000
T36 Poisoning by systemic antibiotics
0.645 0.355 0.000
J22 Unspecified acute lower respiratory infection
0.644 0.356 0.000
O48 Prolonged pregnancy
0.643 0.357 0.000
B35-B49 Mycoses
0.642 0.358 0.000
N95 Menopausal and other perimenopausal disorders
0.641 0.359 0.000
N20-N23 Urolithiasis
0.640 0.360 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.640 0.360 0.000
Chapter IX Diseases of the circulatory system
0.638 0.362 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.638 0.362 0.000
H27 Other disorders of lens
0.638 0.362 0.000
G70-G73 Diseases of myoneural junction and muscle
0.638 0.362 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.638 0.362 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.638 0.362 0.000
M23.8 Other internal derangements of knee
0.636 0.364 0.000
O45 Premature separation of placenta [abruptio placentae]
0.634 0.366 0.000
O44 Placenta praevia
0.634 0.366 0.000
O43 Placental disorders
0.634 0.366 0.000
O41 Other disorders of amniotic fluid and membranes
0.634 0.366 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.634 0.366 0.000
O33 Maternal care for known or suspected disproportion
0.634 0.366 0.000
O31 Complications specific to multiple gestation
0.634 0.366 0.000
O30 Multiple gestation
0.634 0.366 0.000
O40 Polyhydramnios
0.634 0.366 0.000
J33.9 Nasal polyp, unspecified
0.633 0.367 0.000
H33.3 Retinal breaks without detachment
0.633 0.367 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.632 0.367 0.000
N60 Benign mammary dysplasia
0.632 0.368 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.628 0.372 0.000
J30 Vasomotor and allergic rhinitis
0.628 0.372 0.000
N89 Other noninflammatory disorders of vagina
0.626 0.374 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.626 0.374 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.625 0.375 0.000
M77 Other enthesopathies
0.625 0.375 0.000
M76 Enthesopathies of lower limb, excluding foot
0.625 0.375 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.625 0.375 0.000
M71 Other bursopathies
0.625 0.375 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.625 0.375 0.000
F33 Recurrent depressive disorder
0.625 0.375 0.000
Chapter XXI Factors influencing health status and contact with health services
0.623 0.377 0.000
F31.9 Bipolar affective disorder, unspecified
0.623 0.377 0.000
S82 Fracture of lower leg, including ankle
0.621 0.379 0.000
L50-L54 Urticaria and erythema
0.621 0.379 0.000
L10-L14 Bullous disorders
0.621 0.379 0.000
J84 Other interstitial pulmonary diseases
0.621 0.379 0.000
N37 Urethral disorders in diseases classified elsewhere
0.621 0.379 0.000
N36 Other disorders of urethra
0.621 0.379 0.000
N34 Urethritis and urethral syndrome
0.621 0.379 0.000
N33 Bladder disorders in diseases classified elsewhere
0.621 0.379 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.621 0.379 0.000
S68 Traumatic amputation of wrist and hand
0.619 0.381 0.000
M24 Other specific joint derangements
0.618 0.382 0.000
J36 Peritonsillar abscess
0.617 0.383 0.000
N85.0 Endometrial glandular hyperplasia
0.616 0.384 0.000
O63 Long labour
0.615 0.385 0.000
B99-B99 Other infectious diseases
0.615 0.385 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.615 0.385 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.615 0.385 0.000
B65-B83 Helminthiases
0.615 0.385 0.000
B50-B64 Protozoal diseases
0.615 0.385 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.615 0.385 0.000
B15-B19 Viral hepatitis
0.615 0.385 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.615 0.385 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.615 0.385 0.000
A80-A89 Viral infections of the central nervous system
0.615 0.385 0.000
A75-A79 Rickettsioses
0.615 0.385 0.000
A70-A74 Other diseases caused by chlamydiae
0.615 0.385 0.000
A65-A69 Other spirochaetal diseases
0.615 0.385 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.615 0.385 0.000
A20-A28 Certain zoonotic bacterial diseases
0.615 0.385 0.000
A15-A19 Tuberculosis
0.615 0.385 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.615 0.385 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.614 0.386 0.000
E20-E35 Disorders of other endocrine glands
0.613 0.386 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.613 0.387 0.000
O74 Complications of anaesthesia during labour and delivery
0.613 0.387 0.000
O73 Retained placenta and membranes, without haemorrhage
0.613 0.387 0.000
O71 Other obstetric trauma
0.613 0.387 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.613 0.387 0.000
O66 Other obstructed labour
0.613 0.387 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.613 0.387 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.613 0.387 0.000
O62 Abnormalities of forces of labour
0.613 0.387 0.000
O61 Failed induction of labour
0.613 0.387 0.000
O60 Preterm delivery
0.613 0.387 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.613 0.387 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.612 0.388 0.000
M31 Other necrotising vasculopathies
0.612 0.388 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.611 0.388 0.000
T18 Foreign body in alimentary tract
0.611 0.389 0.000
F05.9 Delirium, unspecified
0.611 0.389 0.000
M23.3 Other meniscus derangements
0.610 0.390 0.000
M50-M54 Other dorsopathies
0.609 0.391 0.000
J92 Pleural plaque
0.608 0.392 0.000
T40.2 Other opioids
0.608 0.392 0.000
O84 Multiple delivery
0.607 0.392 0.000
O83 Other assisted single delivery
0.607 0.392 0.000
O82 Single delivery by Caesarean section
0.607 0.392 0.000
O81 Single delivery by forceps and vacuum extractor
0.607 0.392 0.000
T39.1 4-Aminophenol derivatives
0.607 0.393 0.000
G93.3 Postviral fatigue syndrome
0.607 0.393 0.000
H34 Retinal vascular occlusions
0.606 0.394 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.606 0.394 0.000
H31 Other disorders of choroid
0.606 0.394 0.000
H30 Chorioretinal inflammation
0.606 0.394 0.000
N40 Hyperplasia of prostate
0.606 0.394 0.000
S89 Other and unspecified injuries of lower leg
0.605 0.395 0.000
S88 Traumatic amputation of lower leg
0.605 0.395 0.000
S87 Crushing injury of lower leg
0.605 0.395 0.000
S86 Injury of muscle and tendon at lower leg level
0.605 0.395 0.000
S85 Injury of blood vessels at lower leg level
0.605 0.395 0.000
S84 Injury of nerves at lower leg level
0.605 0.395 0.000
M79.6 Pain in limb
0.604 0.396 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.604 0.396 0.000
S02 Fracture of skull and facial bones
0.603 0.397 0.000
M22 Disorders of patella
0.602 0.398 0.000
H00 Hordeolum and chalazion
0.602 0.398 0.000
G57 Mononeuropathies of lower limb
0.600 0.400 0.000
R30-R39 Symptoms and signs involving the urinary system
0.599 0.401 0.000
M05-M14 Inflammatory polyarthropathies
0.598 0.401 0.000
S01 Open wound of head
0.598 0.402 0.000
T78 Adverse effects, not elsewhere classified
0.598 0.402 0.000
N86 Erosion and ectropion of cervix uteri
0.596 0.404 0.000
N63 Unspecified lump in breast
0.594 0.405 0.000
F17.2 Dependence syndrome
0.594 0.406 0.000
S62 Fracture at wrist and hand level
0.594 0.406 0.000
S09 Other and unspecified injuries of head
0.593 0.407 0.000
N61 Inflammatory disorders of breast
0.593 0.407 0.000
N42 Other disorders of prostate
0.593 0.407 0.000
J93.9 Pneumothorax, unspecified
0.592 0.408 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.591 0.409 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.590 0.409 0.000
O72 Postpartum haemorrhage
0.590 0.410 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.588 0.412 0.000
E40-E46 Malnutrition
0.588 0.412 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.588 0.412 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.587 0.413 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.587 0.413 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.587 0.413 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.587 0.413 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.587 0.413 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.587 0.413 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.587 0.413 0.000
F11 Mental and behavioural disorders due to use of opioids
0.587 0.413 0.000
J39 Other diseases of upper respiratory tract
0.587 0.413 0.000
J37 Chronic laryngitis and laryngotracheitis
0.587 0.413 0.000
J35 Chronic diseases of tonsils and adenoids
0.587 0.413 0.000
S69 Other and unspecified injuries of wrist and hand
0.586 0.414 0.000
S67 Crushing injury of wrist and hand
0.586 0.414 0.000
S65 Injury of blood vessels at wrist and hand level
0.586 0.414 0.000
S64 Injury of nerves at wrist and hand level
0.586 0.414 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.586 0.414 0.000
S60 Superficial injury of wrist and hand
0.586 0.414 0.000
M75.8 Other shoulder lesions
0.585 0.415 0.000
M75.9 Shoulder lesion, unspecified
0.585 0.415 0.000
M75.5 Bursitis of shoulder
0.585 0.415 0.000
M75.3 Calcific tendinitis of shoulder
0.585 0.415 0.000
M75.2 Bicipital tendinitis
0.585 0.415 0.000
G20-G26 Extrapyramidal and movement disorders
0.585 0.415 0.000
J32 Chronic sinusitis
0.585 0.415 0.000
A00-A09 Intestinal infectious diseases
0.585 0.415 0.000
J09-J18 Influenza and pneumonia
0.584 0.416 0.000
H26.8 Other specified cataract
0.584 0.416 0.000
W00-W19 Falls
0.584 0.416 0.000
N30.2 Other chronic cystitis
0.584 0.416 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.582 0.417 0.000
N39.0 Urinary tract infection, site not specified
0.582 0.418 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.581 0.419 0.000
M34 Systemic sclerosis
0.581 0.419 0.000
M33 Dermatopolymyositis
0.581 0.419 0.000
M32 Systemic lupus erythematosus
0.581 0.419 0.000
M30 Polyarteritis nodosa and related conditions
0.581 0.419 0.000
M21 Other acquired deformities of limbs
0.581 0.419 0.000
S08 Traumatic amputation of part of head
0.579 0.420 0.000
S07 Crushing injury of head
0.579 0.420 0.000
S06 Intracranial injury
0.579 0.420 0.000
S05 Injury of eye and orbit
0.579 0.420 0.000
S04 Injury of cranial nerves
0.579 0.420 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.579 0.420 0.000
A41 Other septicaemia
0.579 0.421 0.000
F03 Unspecified dementia
0.579 0.421 0.000
N98 Complications associated with artificial fertilisation
0.578 0.422 0.000
N91 Absent, scanty and rare menstruation
0.578 0.422 0.000
N82 Fistulae involving female genital tract
0.578 0.422 0.000
N96 Habitual aborter
0.578 0.422 0.000
M72 Fibroblastic disorders
0.578 0.422 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.577 0.423 0.000
F17.1 Harmful use
0.576 0.424 0.000
O29 Complications of anaesthesia during pregnancy
0.576 0.424 0.000
O28 Abnormal findings on antenatal screening of mother
0.576 0.424 0.000
O24 Diabetes mellitus in pregnancy
0.576 0.424 0.000
O23 Infections of genito-urinary tract in pregnancy
0.576 0.424 0.000
O22 Venous complications in pregnancy
0.576 0.424 0.000
O21 Excessive vomiting in pregnancy
0.576 0.424 0.000
O25 Malnutrition in pregnancy
0.576 0.424 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.575 0.425 0.000
H01.0 Blepharitis
0.575 0.425 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.574 0.426 0.000
J03 Acute tonsillitis
0.573 0.427 0.000
M35 Other systemic involvement of connective tissue
0.572 0.428 0.000
N35.9 Urethral stricture, unspecified
0.571 0.428 0.000
H35 Other retinal disorders
0.571 0.429 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.570 0.430 0.000
N85.4 Malposition of uterus
0.570 0.430 0.000
H25.2 Senile cataract, morgagnian type
0.570 0.430 0.000
H25.9 Senile cataract, unspecified
0.569 0.430 0.000
F38 Other mood [affective] disorders
0.569 0.431 0.000
F34 Persistent mood [affective] disorders
0.569 0.431 0.000
F30 Manic episode
0.569 0.431 0.000
F39 Unspecified mood [affective] disorder
0.569 0.431 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.569 0.431 0.000
T43.2 Other and unspecified antidepressants
0.569 0.431 0.000
J94 Other pleural conditions
0.568 0.432 0.000
J91 Pleural effusion in conditions classified elsewhere
0.568 0.432 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.568 0.432 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.567 0.433 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.567 0.433 0.000
F02 Dementia in other diseases classified elsewhere
0.567 0.433 0.000
F01 Vascular dementia
0.567 0.433 0.000
F00 Dementia in Alzheimer's disease
0.567 0.433 0.000
F09 Unspecified organic or symptomatic mental disorder
0.567 0.433 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.567 0.433 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.566 0.434 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.565 0.435 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.565 0.435 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.565 0.435 0.000
Y35-Y36 Legal intervention and operations of war
0.565 0.435 0.000
Y10-Y34 Event of undetermined intent
0.565 0.435 0.000
Y00-Y09 Assault
0.565 0.435 0.000
X85-X99 Assault
0.565 0.435 0.000
X60-X84 Intentional self-harm
0.565 0.435 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.565 0.435 0.000
X50-X57 Overexertion, travel and privation
0.565 0.435 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.565 0.435 0.000
X30-X39 Exposure to forces of nature
0.565 0.435 0.000
X20-X29 Contact with venomous animals and plants
0.565 0.435 0.000
X10-X19 Contact with heat and hot substances
0.565 0.435 0.000
X00-X09 Exposure to smoke, fire and flames
0.565 0.435 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.565 0.435 0.000
W75-W84 Other accidental threats to breathing
0.565 0.435 0.000
W65-W74 Accidental drowning and submersion
0.565 0.435 0.000
W50-W64 Exposure to animate mechanical forces
0.565 0.435 0.000
W20-W49 Exposure to inanimate mechanical forces
0.565 0.435 0.000
V98-V99 Other and unspecified transport accidents
0.565 0.435 0.000
V95-V97 Air and space transport accidents
0.565 0.435 0.000
V90-V94 Water transport accidents
0.565 0.435 0.000
V80-V89 Other land transport accidents
0.565 0.435 0.000
V70-V79 Bus occupant injured in transport accident
0.565 0.435 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.565 0.435 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.565 0.435 0.000
V40-V49 Car occupant injured in transport accident
0.565 0.435 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.565 0.435 0.000
V20-V29 Motorcycle rider injured in transport accident
0.565 0.435 0.000
V10-V19 Pedal cyclist injured in transport accident
0.565 0.435 0.000
V01-V09 Pedestrian injured in transport accident
0.565 0.435 0.000
N87.0 Mild cervical dysplasia
0.564 0.435 0.000
N64 Other disorders of breast
0.563 0.437 0.000
N62 Hypertrophy of breast
0.563 0.437 0.000
L40 Psoriasis
0.563 0.437 0.000
L20-L30 Dermatitis and eczema
0.562 0.437 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.562 0.438 0.000
B34 Viral infection of unspecified site
0.562 0.438 0.000
N93 Other abnormal uterine and vaginal bleeding
0.562 0.438 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.559 0.440 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.559 0.441 0.000
H53 Visual disturbances
0.558 0.442 0.000
H40-H42 Glaucoma
0.557 0.442 0.001
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.556 0.444 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.555 0.445 0.000
H05 Disorders of orbit
0.555 0.445 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.555 0.445 0.000
G30 Alzheimer's disease
0.554 0.446 0.000
J86 Pyothorax
0.554 0.446 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.554 0.446 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.553 0.447 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.551 0.449 0.000
J21 Acute bronchiolitis
0.550 0.450 0.000
J20 Acute bronchitis
0.550 0.450 0.000
O46.9 Antepartum haemorrhage, unspecified
0.550 0.450 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.550 0.450 0.000
J40-J47 Chronic lower respiratory diseases
0.550 0.450 0.000
T19 Foreign body in genito-urinary tract
0.549 0.451 0.000
T17 Foreign body in respiratory tract
0.549 0.451 0.000
T15 Foreign body on external eye
0.549 0.451 0.000
T16 Foreign body in ear
0.549 0.451 0.000
N50 Other disorders of male genital organs
0.548 0.452 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.548 0.452 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.548 0.452 0.000
T42.4 Benzodiazepines
0.548 0.452 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.547 0.453 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.546 0.454 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.546 0.454 0.000
G40 Epilepsy
0.545 0.455 0.000
L60 Nail disorders
0.545 0.455 0.000
J00 Acute nasopharyngitis [common cold]
0.545 0.455 0.000
H02 Other disorders of eyelid
0.545 0.455 0.000
J90 Pleural effusion, not elsewhere classified
0.544 0.455 0.000
M23.9 Internal derangement of knee, unspecified
0.544 0.456 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.544 0.456 0.000
M23.5 Chronic instability of knee
0.544 0.456 0.000
M23.4 Loose body in knee
0.544 0.456 0.000
M23.1 Discoid meniscus (congenital)
0.544 0.456 0.000
M23.0 Cystic meniscus
0.544 0.456 0.000
N02 Recurrent and persistent haematuria
0.544 0.456 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.544 0.456 0.000
T75 Effects of other external causes
0.543 0.456 0.000
T74 Maltreatment syndromes
0.543 0.456 0.000
T73 Effects of other deprivation
0.543 0.456 0.000
T70 Effects of air pressure and water pressure
0.543 0.456 0.000
T69 Other effects of reduced temperature
0.543 0.456 0.000
T67 Effects of heat and light
0.543 0.456 0.000
T71 Asphyxiation
0.543 0.456 0.000
T68 Hypothermia
0.543 0.456 0.000
T66 Unspecified effects of radiation
0.543 0.456 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.543 0.457 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.543 0.457 0.000
N41 Inflammatory diseases of prostate
0.543 0.457 0.000
N46 Male infertility
0.543 0.457 0.000
N44 Torsion of testis
0.543 0.457 0.000
N30.9 Cystitis, unspecified
0.543 0.457 0.000
H26.3 Drug-induced cataract
0.542 0.457 0.000
H26.2 Complicated cataract
0.542 0.457 0.000
H26.1 Traumatic cataract
0.542 0.457 0.000
H26.0 Infantile, juvenile and presenile cataract
0.542 0.457 0.000
H33.5 Other retinal detachments
0.542 0.458 0.000
H33.4 Traction detachment of retina
0.542 0.458 0.000
H33.1 Retinoschisis and retinal cysts
0.542 0.458 0.000
H25.0 Senile incipient cataract
0.542 0.458 0.000
M79.7 Fibromyalgia
0.542 0.458 0.000
S81.0 Open wound of knee
0.541 0.459 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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