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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74925736
log Bayes Factor = 13.7815
Chromosome 5   position 150,711,917  (GRCh37) Explore rs74925736 on Ensembl!
Variant rs74925736 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
Chapter II Neoplasms
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.978 0.022 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.976 0.024 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
J40-J47 Chronic lower respiratory diseases
0.974 0.026 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
J44 Other chronic obstructive pulmonary disease
0.970 0.030 0.000
B95-B98 Bacterial, viral and other infectious agents
0.963 0.037 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.962 0.038 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.958 0.042 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.951 0.049 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.950 0.050 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.945 0.055 0.000
M05-M14 Inflammatory polyarthropathies
0.940 0.060 0.000
C15-C26 Malignant neoplasms of digestive organs
0.939 0.061 0.000
A30-A49 Other bacterial diseases
0.938 0.062 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.932 0.068 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.928 0.072 0.000
I51 Complications and ill-defined descriptions of heart disease
0.928 0.072 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.926 0.074 0.000
L90 Atrophic disorders of skin
0.923 0.077 0.000
C15 Malignant neoplasm of oesophagus
0.923 0.077 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.923 0.077 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.921 0.079 0.000
L82 Seborrhoeic keratosis
0.920 0.080 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.920 0.080 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.917 0.083 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.912 0.088 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.910 0.090 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.909 0.091 0.000
G90-G99 Other disorders of the nervous system
0.909 0.091 0.000
S00-S09 Injuries to the head
0.904 0.096 0.000
M13 Other arthritis
0.900 0.100 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.899 0.101 0.000
L90.5 Scar conditions and fibrosis of skin
0.896 0.104 0.000
M70-M79 Other soft tissue disorders
0.894 0.106 0.000
I60-I69 Cerebrovascular diseases
0.893 0.107 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.892 0.108 0.000
M20-M25 Other joint disorders
0.889 0.111 0.000
I77 Other disorders of arteries and arterioles
0.888 0.112 0.000
C15.9 Oesophagus, unspecified
0.884 0.116 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.884 0.116 0.000
I05-I09 Chronic rheumatic heart diseases
0.878 0.122 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.877 0.123 0.000
A00-A09 Intestinal infectious diseases
0.876 0.124 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.876 0.124 0.000
C78.0 Secondary malignant neoplasm of lung
0.876 0.124 0.000
L89 Decubitus ulcer
0.872 0.128 0.000
C51-C58 Malignant neoplasms of female genital organs
0.871 0.129 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.868 0.132 0.000
M13.9 Arthritis, unspecified
0.866 0.134 0.000
I35 Nonrheumatic aortic valve disorders
0.865 0.135 0.000
I51.7 Cardiomegaly
0.863 0.137 0.000
C34 Malignant neoplasm of bronchus and lung
0.863 0.137 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.859 0.141 0.000
Y42.7 Androgens and anabolic congeners
0.855 0.145 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.853 0.147 0.000
J90-J94 Other diseases of pleura
0.853 0.147 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.853 0.147 0.000
Chapter VII Diseases of the eye and adnexa
0.849 0.151 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.846 0.154 0.000
T81 Complications of procedures, not elsewhere classified
0.846 0.154 0.000
C15.5 Lower third of oesophagus
0.846 0.154 0.000
G62 Other polyneuropathies
0.845 0.155 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.841 0.159 0.000
A80-A89 Viral infections of the central nervous system
0.840 0.160 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.837 0.163 0.000
A41 Other septicaemia
0.836 0.164 0.000
M23 Internal derangement of knee
0.834 0.166 0.000
G30-G32 Other degenerative diseases of the nervous system
0.830 0.170 0.000
G93 Other disorders of brain
0.829 0.171 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.828 0.172 0.000
M24 Other specific joint derangements
0.828 0.172 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.828 0.172 0.000
M45-M49 Spondylopathies
0.827 0.172 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.824 0.176 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.824 0.176 0.000
C78.2 Secondary malignant neoplasm of pleura
0.824 0.176 0.000
A49 Bacterial infection of unspecified site
0.824 0.176 0.000
I46 Cardiac arrest
0.824 0.176 0.000
B65-B83 Helminthiases
0.822 0.178 0.000
S00 Superficial injury of head
0.821 0.179 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
J43 Emphysema
0.821 0.179 0.000
L81 Other disorders of pigmentation
0.818 0.182 0.000
J00-J06 Acute upper respiratory infections
0.817 0.183 0.000
S90-S99 Injuries to the ankle and foot
0.816 0.184 0.000
C64-C68 Malignant neoplasms of urinary tract
0.815 0.185 0.000
M10 Gout
0.815 0.185 0.000
I27 Other pulmonary heart diseases
0.815 0.185 0.000
A41.9 Septicaemia, unspecified
0.814 0.186 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.812 0.188 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.812 0.188 0.000
J20-J22 Other acute lower respiratory infections
0.811 0.189 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.810 0.189 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.808 0.192 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
Y43 Primarily systemic agents
0.805 0.195 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.801 0.199 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.801 0.199 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.800 0.200 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.798 0.202 0.000
Q60-Q64 Congenital malformations of the urinary system
0.797 0.203 0.000
I44 Atrioventricular and left bundle-branch block
0.796 0.204 0.000
Y83.4 Other reconstructive surgery
0.796 0.204 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.794 0.206 0.000
C54 Malignant neoplasm of corpus uteri
0.787 0.213 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.785 0.215 0.000
D69 Purpura and other haemorrhagic conditions
0.785 0.215 0.000
I51.8 Other ill-defined heart diseases
0.785 0.215 0.000
M24.1 Other articular cartilage disorders
0.784 0.216 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.783 0.217 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.783 0.217 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.782 0.218 0.000
C34.9 Bronchus or lung, unspecified
0.781 0.219 0.000
I71 Aortic aneurysm and dissection
0.779 0.221 0.000
Chapter XIV Diseases of the genitourinary system
0.779 0.221 0.000
H10-H13 Disorders of conjunctiva
0.777 0.223 0.000
L60-L75 Disorders of skin appendages
0.776 0.224 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.773 0.227 0.000
M40-M43 Deforming dorsopathies
0.771 0.229 0.000
I45 Other conduction disorders
0.771 0.229 0.000
I34 Nonrheumatic mitral valve disorders
0.770 0.230 0.000
I73 Other peripheral vascular diseases
0.770 0.230 0.000
Q50-Q56 Congenital malformations of genital organs
0.769 0.231 0.000
C32 Malignant neoplasm of larynx
0.768 0.232 0.000
M91-M94 Chondropathies
0.766 0.234 0.000
S06 Intracranial injury
0.766 0.234 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.766 0.234 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
S60-S69 Injuries to the wrist and hand
0.765 0.235 0.000
A08 Viral and other specified intestinal infections
0.765 0.235 0.000
I35.0 Aortic (valve) stenosis
0.764 0.236 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.764 0.236 0.000
D68 Other coagulation defects
0.764 0.236 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.763 0.237 0.000
L20-L30 Dermatitis and eczema
0.762 0.238 0.000
Y48 Anaesthetics and therapeutic gases
0.762 0.238 0.000
Q80-Q89 Other congenital malformations
0.762 0.238 0.000
J95-J99 Other diseases of the respiratory system
0.761 0.239 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.760 0.240 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.758 0.242 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.758 0.242 0.000
I27.0 Primary pulmonary hypertension
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.758 0.242 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.757 0.243 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.757 0.243 0.000
G70-G73 Diseases of myoneural junction and muscle
0.756 0.243 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.756 0.244 0.000
Y42.5 Other oestrogens and progestogens
0.756 0.244 0.000
L83 Acanthosis nigricans
0.755 0.245 0.000
J60-J70 Lung diseases due to external agents
0.755 0.245 0.000
D69.6 Thrombocytopenia, unspecified
0.755 0.245 0.000
G62.9 Polyneuropathy, unspecified
0.754 0.246 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.752 0.248 0.000
Chapter VIII Diseases of the ear and mastoid process
0.749 0.251 0.000
B25-B34 Other viral diseases
0.748 0.252 0.000
S05 Injury of eye and orbit
0.748 0.252 0.000
Y40 Systemic antibiotics
0.748 0.252 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.748 0.252 0.000
M48 Other spondylopathies
0.747 0.253 0.000
S50-S59 Injuries to the elbow and forearm
0.747 0.253 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.745 0.255 0.000
I69 Sequelae of cerebrovascular disease
0.745 0.255 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.744 0.255 0.000
W00-W19 Falls
0.744 0.256 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.744 0.256 0.000
C20 Malignant neoplasm of rectum
0.743 0.257 0.000
I36 Nonrheumatic tricuspid valve disorders
0.743 0.257 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.743 0.257 0.000
I77.6 Arteritis, unspecified
0.741 0.259 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.740 0.260 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.739 0.261 0.000
M79.2 Neuralgia and neuritis, unspecified
0.738 0.262 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.738 0.262 0.000
I08 Multiple valve diseases
0.737 0.263 0.000
I77.1 Stricture of artery
0.737 0.263 0.000
M86-M90 Other osteopathies
0.737 0.263 0.000
M13.98 Arthritis, unspecified (Other)
0.737 0.263 0.000
T86 Failure and rejection of transplanted organs and tissues
0.736 0.264 0.000
I72 Other aneurysm
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.735 0.265 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.735 0.265 0.000
T39.0 Salicylates
0.735 0.265 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.734 0.266 0.000
L93 Lupus erythematosus
0.733 0.266 0.000
A49.8 Other bacterial infections of unspecified site
0.733 0.266 0.000
M80 Osteoporosis with pathological fracture
0.733 0.267 0.000
M79.7 Fibromyalgia
0.732 0.268 0.000
Y57 Other and unspecified drugs and medicaments
0.732 0.268 0.000
L84 Corns and callosities
0.731 0.269 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.731 0.269 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.730 0.270 0.000
G93.8 Other specified disorders of brain
0.730 0.270 0.000
I47 Paroxysmal tachycardia
0.730 0.270 0.000
T42.4 Benzodiazepines
0.729 0.271 0.000
E10-E14 Diabetes mellitus
0.728 0.272 0.000
M00-M03 Infectious arthropathies
0.728 0.272 0.000
I61 Intracerebral haemorrhage
0.728 0.272 0.000
H11 Other disorders of conjunctiva
0.727 0.273 0.000
C54.1 Endometrium
0.727 0.273 0.000
A87 Viral meningitis
0.727 0.273 0.000
N00-N08 Glomerular diseases
0.726 0.273 0.000
M10.9 Gout, unspecified
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.725 0.275 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.275 0.000
T92 Sequelae of injuries of upper limb
0.724 0.276 0.000
I51.6 Cardiovascular disease, unspecified
0.723 0.277 0.000
I05 Rheumatic mitral valve diseases
0.720 0.280 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.718 0.282 0.000
Y83.3 Surgical operation with formation of external stoma
0.718 0.282 0.000
O30 Multiple gestation
0.718 0.282 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.718 0.282 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M15-M19 Arthrosis
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
D48.5 Skin
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.714 0.286 0.000
L91 Hypertrophic disorders of skin
0.714 0.286 0.000
G62.8 Other specified polyneuropathies
0.713 0.287 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.713 0.287 0.000
L50-L54 Urticaria and erythema
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
J43.9 Emphysema, unspecified
0.711 0.289 0.000
C21 Malignant neoplasm of anus and anal canal
0.711 0.289 0.000
G91 Hydrocephalus
0.711 0.289 0.000
J42 Unspecified chronic bronchitis
0.710 0.289 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.711 0.289 0.000
C16 Malignant neoplasm of stomach
0.710 0.290 0.000
S00.8 Superficial injury of other parts of head
0.710 0.290 0.000
C67 Malignant neoplasm of bladder
0.710 0.290 0.000
M79.1 Myalgia
0.709 0.291 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
S02 Fracture of skull and facial bones
0.707 0.293 0.000
I38 Endocarditis, valve unspecified
0.706 0.294 0.000
J00 Acute nasopharyngitis [common cold]
0.706 0.294 0.000
L89.3 Stage IV decubitus ulcer
0.705 0.295 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
H30-H36 Disorders of choroid and retina
0.704 0.296 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.703 0.297 0.000
I60 Subarachnoid haemorrhage
0.703 0.297 0.000
N99-N99 Other disorders of the genitourinary system
0.702 0.298 0.000
B07 Viral warts
0.702 0.298 0.000
L81.4 Other melanin hyperpigmentation
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.702 0.298 0.000
M34 Systemic sclerosis
0.702 0.298 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.702 0.298 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.702 0.298 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.700 0.300 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.700 0.300 0.000
L94 Other localised connective tissue disorders
0.700 0.300 0.000
L87 Transepidermal elimination disorders
0.700 0.300 0.000
L88 Pyoderma gangrenosum
0.700 0.300 0.000
L86 Keratoderma in diseases classified elsewhere
0.700 0.300 0.000
L80 Vitiligo
0.700 0.300 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.300 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
B02 Zoster [herpes zoster]
0.699 0.301 0.000
D48.7 Other specified sites
0.699 0.301 0.000
J41 Simple and mucopurulent chronic bronchitis
0.698 0.301 0.000
D37.4 Colon
0.698 0.302 0.000
M81 Osteoporosis without pathological fracture
0.698 0.302 0.000
G20-G26 Extrapyramidal and movement disorders
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.697 0.303 0.000
M21 Other acquired deformities of limbs
0.696 0.304 0.000
I77.0 Arteriovenous fistula, acquired
0.696 0.304 0.000
G95 Other diseases of spinal cord
0.696 0.304 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.695 0.304 0.000
H55-H59 Other disorders of eye and adnexa
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
B80 Enterobiasis
0.695 0.305 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.692 0.308 0.000
Y43.3 Other antineoplastic drugs
0.692 0.308 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.690 0.310 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.690 0.310 0.000
M48.0 Spinal stenosis
0.690 0.310 0.000
G90 Disorders of autonomic nervous system
0.689 0.311 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.689 0.311 0.000
O20 Haemorrhage in early pregnancy
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.688 0.312 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.688 0.312 0.000
Q61 Cystic kidney disease
0.688 0.312 0.000
I46.9 Cardiac arrest, unspecified
0.688 0.312 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.687 0.313 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
Y59 Other and unspecified vaccines and biological substances
0.687 0.313 0.000
Y58 Bacterial vaccines
0.687 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.687 0.313 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.687 0.313 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.687 0.313 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.687 0.313 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.687 0.313 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.687 0.313 0.000
O41 Other disorders of amniotic fluid and membranes
0.686 0.314 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.686 0.314 0.000
S20-S29 Injuries to the thorax
0.685 0.314 0.000
G62.0 Drug-induced polyneuropathy
0.685 0.315 0.000
J90 Pleural effusion, not elsewhere classified
0.684 0.316 0.000
M13.0 Polyarthritis, unspecified
0.684 0.316 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.683 0.317 0.000
L73 Other follicular disorders
0.683 0.317 0.000
N72 Inflammatory disease of cervix uteri
0.682 0.318 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.682 0.318 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.681 0.319 0.000
Q35-Q37 Cleft lip and cleft palate
0.681 0.319 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.681 0.319 0.000
Q00-Q07 Congenital malformations of the nervous system
0.681 0.319 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.681 0.319 0.000
D68.8 Other specified coagulation defects
0.680 0.320 0.000
J40 Bronchitis, not specified as acute or chronic
0.680 0.320 0.000
C80 Malignant neoplasm without specification of site
0.680 0.320 0.000
I70 Atherosclerosis
0.680 0.320 0.000
G96 Other disorders of central nervous system
0.680 0.320 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.680 0.320 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.679 0.320 0.000
H80-H83 Diseases of inner ear
0.679 0.321 0.000
I33 Acute and subacute endocarditis
0.678 0.321 0.000
N03 Chronic nephritic syndrome
0.678 0.322 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.678 0.322 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.678 0.322 0.000
J46 Status asthmaticus
0.678 0.322 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.677 0.323 0.000
V10-V19 Pedal cyclist injured in transport accident
0.676 0.323 0.000
M79.0 Rheumatism, unspecified
0.676 0.324 0.000
M79.8 Other specified soft tissue disorders
0.676 0.324 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.324 0.000
D80-D89 Certain disorders involving the immune mechanism
0.675 0.325 0.000
M12 Other specific arthropathies
0.674 0.326 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.674 0.326 0.000
M08 Juvenile arthritis
0.674 0.326 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.674 0.326 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.673 0.327 0.000
C17 Malignant neoplasm of small intestine
0.673 0.327 0.000
C23 Malignant neoplasm of gallbladder
0.673 0.327 0.000
G61 Inflammatory polyneuropathy
0.673 0.327 0.000
A48 Other bacterial diseases, not elsewhere classified
0.672 0.328 0.000
A44 Bartonellosis
0.672 0.328 0.000
A43 Nocardiosis
0.672 0.328 0.000
A42 Actinomycosis
0.672 0.328 0.000
A40 Streptococcal septicaemia
0.672 0.328 0.000
A39 Meningococcal infection
0.672 0.328 0.000
A37 Whooping cough
0.672 0.328 0.000
A36 Diphtheria
0.672 0.328 0.000
A32 Listeriosis
0.672 0.328 0.000
A31 Infection due to other mycobacteria
0.672 0.328 0.000
A30 Leprosy [Hansen's disease]
0.672 0.328 0.000
A38 Scarlet fever
0.672 0.328 0.000
A35 Other tetanus
0.672 0.328 0.000
A34 Obstetrical tetanus
0.672 0.328 0.000
A33 Tetanus neonatorum
0.672 0.328 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.672 0.328 0.000
M48.06 Spinal stenosis (Lumbar region)
0.671 0.329 0.000
O85-O92 Complications predominantly related to the puerperium
0.671 0.329 0.000
M07 Psoriatic and enteropathic arthropathies
0.670 0.330 0.000
A46 Erysipelas
0.670 0.330 0.000
L89.1 Stage II decubitus ulcer
0.670 0.330 0.000
C34.2 Middle lobe, bronchus or lung
0.670 0.330 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.331 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.668 0.332 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.668 0.332 0.000
C31 Malignant neoplasm of accessory sinuses
0.668 0.332 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.668 0.332 0.000
C37 Malignant neoplasm of thymus
0.668 0.332 0.000
C33 Malignant neoplasm of trachea
0.668 0.332 0.000
H11.3 Conjunctival haemorrhage
0.668 0.332 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
C34.0 Main bronchus
0.668 0.332 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
A02 Other Salmonella infections
0.667 0.333 0.000
M72 Fibroblastic disorders
0.667 0.333 0.000
J93 Pneumothorax
0.667 0.333 0.000
A49.1 Streptococcal infection, unspecified
0.666 0.334 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.666 0.334 0.000
I51.5 Myocardial degeneration
0.665 0.335 0.000
I51.4 Myocarditis, unspecified
0.665 0.335 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.665 0.335 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.665 0.335 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.665 0.335 0.000
I51.0 Cardiac septal defect, acquired
0.665 0.335 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.665 0.335 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.665 0.335 0.000
M23.8 Other internal derangements of knee
0.664 0.336 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.663 0.337 0.000
I30 Acute pericarditis
0.662 0.337 0.000
L90.9 Atrophic disorder of skin, unspecified
0.662 0.338 0.000
L90.8 Other atrophic disorders of skin
0.662 0.338 0.000
L90.6 Striae atrophicae
0.662 0.338 0.000
L90.4 Acrodermatitis chronica atrophicans
0.662 0.338 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.662 0.338 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.662 0.338 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.662 0.338 0.000
C15.8 Overlapping lesion of oesophagus
0.662 0.338 0.000
C15.4 Middle third of oesophagus
0.662 0.338 0.000
C15.3 Upper third of oesophagus
0.662 0.338 0.000
C15.2 Abdominal part of oesophagus
0.662 0.338 0.000
C15.1 Thoracic part of oesophagus
0.662 0.338 0.000
C15.0 Cervical part of oesophagus
0.662 0.338 0.000
T87 Complications peculiar to reattachment and amputation
0.662 0.338 0.000
M05 Seropositive rheumatoid arthritis
0.662 0.338 0.000
O44 Placenta praevia
0.661 0.338 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.661 0.339 0.000
Y42.9 Other and unspecified hormone antagonists
0.659 0.340 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.659 0.340 0.000
Y42.4 Oral contraceptives
0.659 0.340 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.659 0.340 0.000
Y42.2 Antithyroid drugs
0.659 0.340 0.000
Y42.1 Thyroid hormones and substitutes
0.659 0.340 0.000
O21 Excessive vomiting in pregnancy
0.659 0.341 0.000
M13.93 Arthritis, unspecified (Forearm)
0.659 0.341 0.000
S00.0 Superficial injury of scalp
0.658 0.341 0.000
Y83.0 Surgical operation with transplant of whole organ
0.658 0.342 0.000
S91 Open wound of ankle and foot
0.658 0.342 0.000
G93.4 Encephalopathy, unspecified
0.658 0.342 0.000
H53-H54 Visual disturbances and blindness
0.657 0.343 0.000
J91 Pleural effusion in conditions classified elsewhere
0.656 0.343 0.000
G93.2 Benign intracranial hypertension
0.656 0.344 0.000
S40-S49 Injuries to the shoulder and upper arm
0.655 0.345 0.000
D50-D53 Nutritional anaemias
0.655 0.345 0.000
Y95 Nosocomial condition
0.654 0.346 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.654 0.346 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.654 0.346 0.000
B15-B19 Viral hepatitis
0.653 0.346 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.652 0.347 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.651 0.348 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.651 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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