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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75030245
log Bayes Factor = 16.7045
Chromosome 1   position 209,331,985  (GRCh37) Explore rs75030245 on Ensembl!
Variant rs75030245 is part of Cluster X0131

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
Chapter II Neoplasms
0.991 0.009 0.000
T39.1 4-Aminophenol derivatives
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.985 0.015 0.000
S61 Open wound of wrist and hand
0.983 0.017 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
E10 Insulin-dependent diabetes mellitus
0.978 0.022 0.000
E86 Volume depletion
0.977 0.023 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.968 0.032 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.965 0.035 0.000
D10-D36 Benign neoplasms
0.964 0.036 0.000
Chapter V Mental and behavioural disorders
0.962 0.038 0.000
R11 Nausea and vomiting
0.959 0.041 0.000
E87.2 Acidosis
0.956 0.044 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.949 0.051 0.000
R50-R69 General symptoms and signs
0.945 0.055 0.000
S61.0 Open wound of finger(s) without damage to nail
0.945 0.055 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.942 0.058 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.938 0.062 0.000
R47-R49 Symptoms and signs involving speech and voice
0.930 0.070 0.000
R19.4 Change in bowel habit
0.929 0.071 0.000
H30-H36 Disorders of choroid and retina
0.928 0.072 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.926 0.074 0.000
C83.3 Large cell (diffuse)
0.922 0.078 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.922 0.078 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.921 0.079 0.000
F30-F39 Mood [affective] disorders
0.918 0.082 0.000
E11 Non-insulin-dependent diabetes mellitus
0.918 0.082 0.000
S61.1 Open wound of finger(s) with damage to nail
0.916 0.084 0.000
D23 Other benign neoplasms of skin
0.916 0.084 0.000
A30-A49 Other bacterial diseases
0.914 0.086 0.000
C64-C68 Malignant neoplasms of urinary tract
0.913 0.087 0.000
E10.3 With ophthalmic complications
0.912 0.088 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.911 0.089 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.910 0.090 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.909 0.091 0.000
D22 Melanocytic naevi
0.907 0.093 0.000
E20-E35 Disorders of other endocrine glands
0.906 0.094 0.000
S62 Fracture at wrist and hand level
0.905 0.095 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.903 0.097 0.000
Chapter VI Diseases of the nervous system
0.902 0.098 0.000
T79-T79 Certain early complications of trauma
0.902 0.098 0.000
B95-B98 Bacterial, viral and other infectious agents
0.901 0.099 0.000
H43-H45 Disorders of vitreous body and globe
0.901 0.099 0.000
R20 Disturbances of skin sensation
0.900 0.100 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.897 0.103 0.000
Chapter X Diseases of the respiratory system
0.892 0.108 0.000
D70 Agranulocytosis
0.889 0.111 0.000
R56 Convulsions, not elsewhere classified
0.889 0.111 0.000
R55 Syncope and collapse
0.886 0.114 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.886 0.114 0.000
H36 Retinal disorders in diseases classified elsewhere
0.885 0.115 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.884 0.116 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.879 0.121 0.000
E10.4 With neurological complications
0.876 0.124 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.871 0.129 0.000
J09-J18 Influenza and pneumonia
0.869 0.131 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.868 0.132 0.000
D23.5 Skin of trunk
0.867 0.133 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.866 0.134 0.000
A41 Other septicaemia
0.865 0.135 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.865 0.135 0.000
J90-J94 Other diseases of pleura
0.864 0.136 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.864 0.136 0.000
E10.9 Without complications
0.862 0.138 0.000
E87.5 Hyperkalaemia
0.861 0.139 0.000
J18 Pneumonia, organism unspecified
0.857 0.143 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.857 0.143 0.000
H36.0 Diabetic retinopathy
0.853 0.147 0.000
R60 Oedema, not elsewhere classified
0.853 0.147 0.000
Chapter XXII Codes for special purposes
0.852 0.148 0.000
E11.3 With ophthalmic complications
0.850 0.150 0.000
R40 Somnolence, stupor and coma
0.849 0.151 0.000
H43 Disorders of vitreous body
0.849 0.151 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.848 0.152 0.000
R56.8 Other and unspecified convulsions
0.848 0.152 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.848 0.152 0.000
M50-M54 Other dorsopathies
0.847 0.153 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.846 0.154 0.000
T51 Toxic effect of alcohol
0.845 0.155 0.000
T39.0 Salicylates
0.845 0.155 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.843 0.157 0.000
R49 Voice disturbances
0.841 0.159 0.000
F31 Bipolar affective disorder
0.840 0.160 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.839 0.161 0.000
S50-S59 Injuries to the elbow and forearm
0.836 0.164 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.831 0.169 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.830 0.170 0.000
T86 Failure and rejection of transplanted organs and tissues
0.828 0.172 0.000
S70-S79 Injuries to the hip and thigh
0.825 0.174 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.824 0.176 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.823 0.177 0.000
J18.1 Lobar pneumonia, unspecified
0.821 0.179 0.000
J90 Pleural effusion, not elsewhere classified
0.819 0.181 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.819 0.181 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.818 0.182 0.000
R60.0 Localised oedema
0.817 0.183 0.000
S20-S29 Injuries to the thorax
0.816 0.184 0.000
E11.4 With neurological complications
0.816 0.184 0.000
E50-E64 Other nutritional deficiencies
0.816 0.184 0.000
S00-S09 Injuries to the head
0.813 0.187 0.000
D12.2 Ascending colon
0.812 0.188 0.000
M86-M90 Other osteopathies
0.811 0.189 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.810 0.190 0.000
H53-H54 Visual disturbances and blindness
0.810 0.190 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.809 0.191 0.000
C79 Secondary malignant neoplasm of other sites
0.808 0.192 0.000
W20-W49 Exposure to inanimate mechanical forces
0.808 0.192 0.000
A00-A09 Intestinal infectious diseases
0.806 0.194 0.000
Y45.0 Opioids and related analgesics
0.805 0.195 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.805 0.195 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.803 0.197 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.799 0.201 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.797 0.203 0.000
Chapter VIII Diseases of the ear and mastoid process
0.796 0.204 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.796 0.204 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.796 0.204 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.794 0.206 0.000
S62.6 Fracture of other finger
0.793 0.206 0.000
C91 Lymphoid leukaemia
0.792 0.208 0.000
E16 Other disorders of pancreatic internal secretion
0.792 0.208 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.790 0.210 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.788 0.211 0.000
B15-B19 Viral hepatitis
0.788 0.212 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.787 0.213 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.787 0.213 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.786 0.214 0.000
M54 Dorsalgia
0.783 0.217 0.000
R47 Speech disturbances, not elsewhere classified
0.783 0.217 0.000
D23.2 Skin of ear and external auricular canal
0.782 0.218 0.000
H35 Other retinal disorders
0.782 0.218 0.000
S60 Superficial injury of wrist and hand
0.781 0.219 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.780 0.220 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.780 0.220 0.000
R73 Elevated blood glucose level
0.777 0.223 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.777 0.223 0.000
R49.0 Dysphonia
0.777 0.223 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.776 0.224 0.000
C92 Myeloid leukaemia
0.775 0.225 0.000
B25-B34 Other viral diseases
0.774 0.226 0.000
R20.2 Paraesthesia of skin
0.773 0.227 0.000
F99-F99 Unspecified mental disorder
0.771 0.229 0.000
S10-S19 Injuries to the neck
0.770 0.230 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.769 0.231 0.000
G90-G99 Other disorders of the nervous system
0.769 0.231 0.000
Y43 Primarily systemic agents
0.768 0.232 0.000
D11 Benign neoplasm of major salivary glands
0.767 0.233 0.000
W00-W19 Falls
0.766 0.234 0.000
R23 Other skin changes
0.763 0.237 0.000
T51.0 Ethanol
0.762 0.238 0.000
A40 Streptococcal septicaemia
0.762 0.238 0.000
D73 Diseases of spleen
0.761 0.239 0.000
C67 Malignant neoplasm of bladder
0.758 0.242 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.758 0.242 0.000
E11.5 With peripheral circulatory complications
0.757 0.243 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.757 0.243 0.000
J93 Pneumothorax
0.757 0.243 0.000
D13.1 Stomach
0.756 0.244 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.756 0.244 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.755 0.245 0.000
M91-M94 Chondropathies
0.753 0.247 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.247 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.753 0.247 0.000
F32 Depressive episode
0.752 0.248 0.000
T79.7 Traumatic subcutaneous emphysema
0.752 0.248 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.751 0.249 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.750 0.250 0.000
G35 Multiple sclerosis
0.749 0.251 0.000
D23.3 Skin of other and unspecified parts of face
0.749 0.251 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.749 0.251 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.748 0.252 0.000
E40-E46 Malnutrition
0.745 0.255 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.745 0.255 0.000
R40.2 Coma, unspecified
0.741 0.259 0.000
J18.9 Pneumonia, unspecified
0.741 0.259 0.000
H01 Other inflammation of eyelid
0.740 0.260 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.739 0.261 0.000
H43.1 Vitreous haemorrhage
0.738 0.262 0.000
R42 Dizziness and giddiness
0.736 0.264 0.000
R14 Flatulence and related conditions
0.735 0.264 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.735 0.265 0.000
H04 Disorders of lachrymal system
0.735 0.265 0.000
H54 Blindness and low vision
0.734 0.266 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.734 0.266 0.000
H00 Hordeolum and chalazion
0.733 0.267 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.731 0.269 0.000
E27 Other disorders of adrenal gland
0.730 0.270 0.000
E29 Testicular dysfunction
0.730 0.270 0.000
Y85 Sequelae of transport accidents
0.730 0.270 0.000
E16.2 Hypoglycaemia, unspecified
0.729 0.271 0.000
Y84.8 Other medical procedures
0.728 0.272 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.727 0.273 0.000
D23.6 Skin of upper limb, including shoulder
0.727 0.273 0.000
E22 Hyperfunction of pituitary gland
0.725 0.275 0.000
F60-F69 Disorders of adult personality and behaviour
0.725 0.275 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.723 0.277 0.000
T88.4 Failed or difficult intubation
0.722 0.278 0.000
E23 Hypofunction and other disorders of pituitary gland
0.721 0.279 0.000
E83 Disorders of mineral metabolism
0.721 0.279 0.000
V80-V89 Other land transport accidents
0.720 0.279 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.720 0.280 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.720 0.280 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.718 0.282 0.000
C85.1 B-cell lymphoma, unspecified
0.717 0.283 0.000
H43.3 Other vitreous opacities
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Y52 Agents primarily affecting the cardiovascular system
0.717 0.283 0.000
F30 Manic episode
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
S65 Injury of blood vessels at wrist and hand level
0.715 0.284 0.000
M20-M25 Other joint disorders
0.715 0.285 0.000
S61.7 Multiple open wounds of wrist and hand
0.715 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.285 0.000
D12.6 Colon, unspecified
0.714 0.286 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.714 0.286 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.714 0.286 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.713 0.287 0.000
S51 Open wound of forearm
0.713 0.287 0.000
E85 Amyloidosis
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.713 0.287 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.713 0.287 0.000
T39.4 Antirheumatics, not elsewhere classified
0.713 0.287 0.000
T39.2 Pyrazolone derivatives
0.713 0.287 0.000
J18.8 Other pneumonia, organism unspecified
0.713 0.287 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.713 0.287 0.000
S67 Crushing injury of wrist and hand
0.712 0.288 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.712 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
R44.1 Visual hallucinations
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
R61 Hyperhidrosis
0.711 0.289 0.000
T51.9 Alcohol, unspecified
0.709 0.291 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.709 0.291 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.709 0.291 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.709 0.291 0.000
S62.3 Fracture of other metacarpal bone
0.708 0.292 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.707 0.293 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.707 0.293 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.707 0.293 0.000
B99-B99 Other infectious diseases
0.706 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.293 0.000
B65-B83 Helminthiases
0.706 0.293 0.000
B50-B64 Protozoal diseases
0.706 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.293 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.293 0.000
A75-A79 Rickettsioses
0.706 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.293 0.000
A65-A69 Other spirochaetal diseases
0.706 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.293 0.000
A15-A19 Tuberculosis
0.706 0.293 0.000
F33 Recurrent depressive disorder
0.706 0.294 0.000
E87.3 Alkalosis
0.705 0.295 0.000
S64 Injury of nerves at wrist and hand level
0.705 0.295 0.000
R52 Pain, not elsewhere classified
0.705 0.295 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.705 0.295 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.705 0.295 0.000
R73.9 Hyperglycaemia, unspecified
0.705 0.295 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.704 0.296 0.000
C95 Leukaemia of unspecified cell type
0.704 0.296 0.000
C94 Other leukaemias of specified cell type
0.704 0.296 0.000
C93 Monocytic leukaemia
0.704 0.296 0.000
C88 Malignant immunoproliferative diseases
0.704 0.296 0.000
C86 Other specified types of T/NK-cell lymphoma
0.704 0.296 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.704 0.296 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.702 0.298 0.000
D23.9 Skin, unspecified
0.702 0.298 0.000
H10-H13 Disorders of conjunctiva
0.702 0.298 0.000
S90-S99 Injuries to the ankle and foot
0.701 0.298 0.000
E10.1 With ketoacidosis
0.701 0.298 0.000
E10.8 With unspecified complications
0.701 0.299 0.000
E10.7 With multiple complications
0.701 0.299 0.000
E10.6 With other specified complications
0.701 0.299 0.000
E10.5 With peripheral circulatory complications
0.701 0.299 0.000
E10.2 With renal complications
0.701 0.299 0.000
E10.0 With coma
0.701 0.299 0.000
H43.8 Other disorders of vitreous body
0.701 0.299 0.000
D13.2 Duodenum
0.699 0.300 0.000
R40.0 Somnolence
0.699 0.300 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.699 0.301 0.000
H90-H95 Other disorders of ear
0.699 0.301 0.000
E87.4 Mixed disorder of acid-base balance
0.699 0.301 0.000
E13 Other specified diabetes mellitus
0.698 0.302 0.000
S69 Other and unspecified injuries of wrist and hand
0.697 0.303 0.000
D24 Benign neoplasm of breast
0.697 0.303 0.000
R59 Enlarged lymph nodes
0.697 0.303 0.000
D36 Benign neoplasm of other and unspecified sites
0.697 0.303 0.000
E87.0 Hyperosmolality and hypernatraemia
0.696 0.304 0.000
M89 Other disorders of bone
0.696 0.304 0.000
D35.2 Pituitary gland
0.694 0.306 0.000
T87 Complications peculiar to reattachment and amputation
0.694 0.306 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.694 0.306 0.000
S62.60 Fracture of other finger (closed)
0.693 0.307 0.000
A08 Viral and other specified intestinal infections
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.692 0.308 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.692 0.308 0.000
R68 Other general symptoms and signs
0.691 0.308 0.000
T90 Sequelae of injuries of head
0.691 0.309 0.000
D31 Benign neoplasm of eye and adnexa
0.691 0.309 0.000
D30 Benign neoplasm of urinary organs
0.691 0.309 0.000
D29 Benign neoplasm of male genital organs
0.691 0.309 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.691 0.309 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.691 0.309 0.000
D19 Benign neoplasm of mesothelial tissue
0.691 0.309 0.000
D16 Benign neoplasm of bone and articular cartilage
0.691 0.309 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.691 0.309 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.691 0.309 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.690 0.310 0.000
C79.2 Secondary malignant neoplasm of skin
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.310 0.000
F80-F89 Disorders of psychological development
0.689 0.310 0.000
F70-F79 Mental retardation
0.689 0.310 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.689 0.311 0.000
S61.8 Open wound of other parts of wrist and hand
0.688 0.312 0.000
R30-R39 Symptoms and signs involving the urinary system
0.688 0.312 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.687 0.313 0.000
M50 Cervical disk disorders
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.685 0.315 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
J94 Other pleural conditions
0.683 0.317 0.000
C81 Hodgkin's disease
0.682 0.318 0.000
M54.5 Low back pain
0.681 0.319 0.000
T79.6 Traumatic ischaemia of muscle
0.681 0.319 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.680 0.320 0.000
C83.7 Burkitt's tumour
0.680 0.320 0.000
C83.6 Undifferentiated (diffuse)
0.680 0.320 0.000
C83.5 Lymphoblastic (diffuse)
0.680 0.320 0.000
C83.4 Immunoblastic (diffuse)
0.680 0.320 0.000
C83.2 Mixed small and large cell (diffuse)
0.680 0.320 0.000
C83.1 Small cleaved cell (diffuse)
0.680 0.320 0.000
C83.0 Small cell (diffuse)
0.680 0.320 0.000
D55-D59 Haemolytic anaemias
0.680 0.320 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.680 0.320 0.000
S68 Traumatic amputation of wrist and hand
0.679 0.321 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.678 0.322 0.000
R62 Lack of expected normal physiological development
0.678 0.322 0.000
R57 Shock, not elsewhere classified
0.678 0.322 0.000
R64 Cachexia
0.678 0.322 0.000
R58 Haemorrhage, not elsewhere classified
0.678 0.322 0.000
R47.1 Dysarthria and anarthria
0.678 0.322 0.000
G95 Other diseases of spinal cord
0.678 0.322 0.000
E11.1 With ketoacidosis
0.677 0.323 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
R46 Symptoms and signs involving appearance and behaviour
0.675 0.324 0.000
R43 Disturbances of smell and taste
0.675 0.324 0.000
R33 Retention of urine
0.675 0.325 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.675 0.325 0.000
E28 Ovarian dysfunction
0.673 0.327 0.000
R19.6 Halitosis
0.673 0.327 0.000
R19.3 Abdominal rigidity
0.673 0.327 0.000
R19.2 Visible peristalsis
0.673 0.327 0.000
R19.1 Abnormal bowel sounds
0.673 0.327 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.672 0.328 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.672 0.328 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.669 0.331 0.000
D12.5 Sigmoid colon
0.669 0.331 0.000
D75 Other diseases of blood and blood-forming organs
0.668 0.332 0.000
S70 Superficial injury of hip and thigh
0.668 0.332 0.000
T85.2 Mechanical complication of intraocular lens
0.667 0.332 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.667 0.333 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.667 0.333 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.666 0.334 0.000
D12.0 Caecum
0.666 0.334 0.000
R74 Abnormal serum enzyme levels
0.666 0.334 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.666 0.334 0.000
H31 Other disorders of choroid
0.666 0.334 0.000
H30 Chorioretinal inflammation
0.666 0.334 0.000
Y44 Agents primarily affecting blood constituents
0.665 0.335 0.000
T63 Toxic effect of contact with venomous animals
0.663 0.336 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.663 0.337 0.000
T42.4 Benzodiazepines
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.338 0.000
S00 Superficial injury of head
0.662 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.661 0.339 0.000
Y58 Bacterial vaccines
0.661 0.339 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.339 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.339 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.661 0.339 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
Y48 Anaesthetics and therapeutic gases
0.661 0.339 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.661 0.339 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.661 0.339 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.660 0.339 0.000
T66-T78 Other and unspecified effects of external causes
0.660 0.339 0.000
R50 Fever of unknown origin
0.660 0.340 0.000
D26 Other benign neoplasms of uterus
0.659 0.341 0.000
E80.4 Gilbert's syndrome
0.658 0.342 0.000
F38 Other mood [affective] disorders
0.658 0.342 0.000
F34 Persistent mood [affective] disorders
0.658 0.342 0.000
F39 Unspecified mood [affective] disorder
0.658 0.342 0.000
E11.8 With unspecified complications
0.658 0.342 0.000
E11.7 With multiple complications
0.658 0.342 0.000
E11.6 With other specified complications
0.658 0.342 0.000
E11.0 With coma
0.658 0.342 0.000
M54.2 Cervicalgia
0.658 0.342 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.658 0.342 0.000
D23.0 Skin of lip
0.657 0.343 0.000
Y43.3 Other antineoplastic drugs
0.657 0.343 0.000
D10 Benign neoplasm of mouth and pharynx
0.656 0.344 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.656 0.344 0.000
C91.1 Chronic lymphocytic leukaemia
0.656 0.344 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.656 0.344 0.000
A48 Other bacterial diseases, not elsewhere classified
0.655 0.345 0.000
A44 Bartonellosis
0.655 0.345 0.000
A43 Nocardiosis
0.655 0.345 0.000
A42 Actinomycosis
0.655 0.345 0.000
A39 Meningococcal infection
0.655 0.345 0.000
A37 Whooping cough
0.655 0.345 0.000
A36 Diphtheria
0.655 0.345 0.000
A32 Listeriosis
0.655 0.345 0.000
A31 Infection due to other mycobacteria
0.655 0.345 0.000
A30 Leprosy [Hansen's disease]
0.655 0.345 0.000
A38 Scarlet fever
0.655 0.345 0.000
A35 Other tetanus
0.655 0.345 0.000
A34 Obstetrical tetanus
0.655 0.345 0.000
A33 Tetanus neonatorum
0.655 0.345 0.000
D73.0 Hyposplenism
0.655 0.345 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.655 0.345 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.654 0.345 0.000
C66 Malignant neoplasm of ureter
0.654 0.345 0.000
C65 Malignant neoplasm of renal pelvis
0.654 0.345 0.000
E88 Other metabolic disorders
0.654 0.346 0.000
M00-M03 Infectious arthropathies
0.654 0.346 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.654 0.346 0.000
T65 Toxic effect of other and unspecified substances
0.653 0.346 0.000
T62 Toxic effect of other noxious substances eaten as food
0.653 0.346 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.653 0.346 0.000
T60 Toxic effect of pesticides
0.653 0.346 0.000
T59 Toxic effect of other gases, fumes and vapours
0.653 0.346 0.000
T57 Toxic effect of other inorganic substances
0.653 0.346 0.000
T56 Toxic effect of metals
0.653 0.346 0.000
T54 Toxic effect of corrosive substances
0.653 0.346 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.653 0.346 0.000
T52 Toxic effect of organic solvents
0.653 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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