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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75036812
log Bayes Factor = 31.3953
Chromosome 20   position 48,915,715  (GRCh37) Explore rs75036812 on Ensembl!
Variant rs75036812 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I20 Angina pectoris
0.997 0.003 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.996 0.004 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.996 0.004 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
I60-I69 Cerebrovascular diseases
0.993 0.007 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.992 0.008 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.988 0.012 0.000
C64-C68 Malignant neoplasms of urinary tract
0.986 0.014 0.000
R00 Abnormalities of heart beat
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.982 0.018 0.000
Z95.1 Presence of aortocoronary bypass graft
0.981 0.019 0.000
I21 Acute myocardial infarction
0.981 0.019 0.000
D10-D36 Benign neoplasms
0.980 0.020 0.000
K70-K77 Diseases of liver
0.980 0.020 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.978 0.022 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.978 0.022 0.000
R00.1 Bradycardia, unspecified
0.977 0.023 0.000
I25.1 Atherosclerotic heart disease
0.975 0.025 0.000
I45 Other conduction disorders
0.975 0.025 0.000
I20.9 Angina pectoris, unspecified
0.974 0.026 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.970 0.030 0.000
R07 Pain in throat and chest
0.966 0.034 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.966 0.034 0.000
K80 Cholelithiasis
0.966 0.034 0.000
C79 Secondary malignant neoplasm of other sites
0.964 0.036 0.000
S00-S09 Injuries to the head
0.964 0.036 0.000
G40-G47 Episodic and paroxysmal disorders
0.962 0.038 0.000
K21 Gastro-oesophageal reflux disease
0.958 0.042 0.000
Chapter V Mental and behavioural disorders
0.957 0.043 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.956 0.044 0.000
K83 Other diseases of biliary tract
0.956 0.044 0.000
S20-S29 Injuries to the thorax
0.952 0.048 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.949 0.051 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.947 0.053 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.945 0.055 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.945 0.055 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.943 0.057 0.000
R11 Nausea and vomiting
0.942 0.058 0.000
I45.1 Other and unspecified right bundle-branch block
0.942 0.058 0.000
K70 Alcoholic liver disease
0.939 0.061 0.000
C80 Malignant neoplasm without specification of site
0.939 0.061 0.000
I20.0 Unstable angina
0.936 0.064 0.000
K29 Gastritis and duodenitis
0.936 0.064 0.000
K65-K67 Diseases of peritoneum
0.936 0.064 0.000
I51 Complications and ill-defined descriptions of heart disease
0.936 0.064 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.932 0.068 0.000
Z94 Transplanted organ and tissue status
0.932 0.068 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.927 0.073 0.000
I63 Cerebral infarction
0.927 0.073 0.000
R50-R69 General symptoms and signs
0.926 0.074 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.924 0.076 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.924 0.076 0.000
I67 Other cerebrovascular diseases
0.921 0.079 0.000
Chapter VIII Diseases of the ear and mastoid process
0.921 0.079 0.000
B95-B98 Bacterial, viral and other infectious agents
0.921 0.079 0.000
K29.7 Gastritis, unspecified
0.919 0.081 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.918 0.082 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.915 0.085 0.000
R47-R49 Symptoms and signs involving speech and voice
0.908 0.092 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.908 0.092 0.000
H65-H75 Diseases of middle ear and mastoid
0.907 0.093 0.000
R55 Syncope and collapse
0.906 0.094 0.000
R07.4 Chest pain, unspecified
0.904 0.096 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.904 0.096 0.000
K83.1 Obstruction of bile duct
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.902 0.098 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.900 0.100 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.896 0.104 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.895 0.105 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.893 0.107 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.893 0.107 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.890 0.110 0.000
I49 Other cardiac arrhythmias
0.890 0.110 0.000
I80 Phlebitis and thrombophlebitis
0.886 0.114 0.000
I31 Other diseases of pericardium
0.884 0.116 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.884 0.116 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.884 0.116 0.000
S02 Fracture of skull and facial bones
0.882 0.118 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.882 0.118 0.000
Z60 Problems related to social environment
0.882 0.118 0.000
O60-O75 Complications of labour and delivery
0.880 0.120 0.000
S01 Open wound of head
0.877 0.123 0.000
R94 Abnormal results of function studies
0.877 0.123 0.000
F30-F39 Mood [affective] disorders
0.876 0.124 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.875 0.125 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.872 0.128 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.872 0.128 0.000
I20.8 Other forms of angina pectoris
0.872 0.128 0.000
Z94.8 Other transplanted organ and tissue status
0.870 0.130 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.868 0.132 0.000
I84 Haemorrhoids
0.866 0.134 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.865 0.135 0.000
I65.2 Occlusion and stenosis of carotid artery
0.865 0.135 0.000
G40 Epilepsy
0.862 0.138 0.000
K85 Acute pancreatitis
0.859 0.141 0.000
Z82.3 Family history of stroke
0.859 0.141 0.000
D12.3 Transverse colon
0.856 0.144 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.854 0.146 0.000
S22.0 Fracture of thoracic vertebra
0.854 0.146 0.000
A30-A49 Other bacterial diseases
0.853 0.147 0.000
K65 Peritonitis
0.850 0.150 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.850 0.150 0.000
Z98 Other postsurgical states
0.849 0.151 0.000
H65 Nonsuppurative otitis media
0.848 0.152 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.847 0.153 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.846 0.154 0.000
R06 Abnormalities of breathing
0.845 0.155 0.000
R07.0 Pain in throat
0.842 0.158 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.841 0.159 0.000
K25 Gastric ulcer
0.841 0.159 0.000
Chapter X Diseases of the respiratory system
0.841 0.159 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.841 0.159 0.000
Z60.2 Living alone
0.838 0.162 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.838 0.162 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.836 0.164 0.000
Chapter XIV Diseases of the genitourinary system
0.835 0.165 0.000
G57 Mononeuropathies of lower limb
0.834 0.166 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.832 0.168 0.000
I26 Pulmonary embolism
0.830 0.170 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.828 0.172 0.000
I62 Other nontraumatic intracranial haemorrhage
0.827 0.173 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.827 0.173 0.000
Z75 Problems related to medical facilities and other health care
0.825 0.175 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.825 0.175 0.000
I84.8 Unspecified haemorrhoids with other complications
0.824 0.176 0.000
R02 Gangrene, not elsewhere classified
0.824 0.176 0.000
Z87 Personal history of other diseases and conditions
0.824 0.176 0.000
K75 Other inflammatory liver diseases
0.823 0.177 0.000
D23 Other benign neoplasms of skin
0.822 0.178 0.000
Z89 Acquired absence of limb
0.822 0.178 0.000
Z92 Personal history of medical treatment
0.822 0.178 0.000
I51.8 Other ill-defined heart diseases
0.822 0.178 0.000
I46 Cardiac arrest
0.821 0.179 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.819 0.181 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.818 0.182 0.000
K26 Duodenal ulcer
0.817 0.183 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.816 0.184 0.000
K70.9 Alcoholic liver disease, unspecified
0.816 0.184 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.816 0.184 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.815 0.185 0.000
I38 Endocarditis, valve unspecified
0.815 0.185 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.814 0.186 0.000
H71 Cholesteatoma of middle ear
0.812 0.188 0.000
I67.2 Cerebral atherosclerosis
0.811 0.189 0.000
D10 Benign neoplasm of mouth and pharynx
0.811 0.189 0.000
K90-K93 Other diseases of the digestive system
0.810 0.190 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.809 0.191 0.000
I67.8 Other specified cerebrovascular diseases
0.808 0.192 0.000
D22 Melanocytic naevi
0.806 0.194 0.000
R47 Speech disturbances, not elsewhere classified
0.806 0.194 0.000
D26 Other benign neoplasms of uterus
0.805 0.195 0.000
J00-J06 Acute upper respiratory infections
0.805 0.195 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.804 0.196 0.000
I51.9 Heart disease, unspecified
0.804 0.196 0.000
K70.3 Alcoholic cirrhosis of liver
0.803 0.197 0.000
R94.5 Abnormal results of liver function studies
0.803 0.197 0.000
R52 Pain, not elsewhere classified
0.801 0.199 0.000
S06 Intracranial injury
0.800 0.200 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.798 0.202 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.797 0.203 0.000
I21.9 Acute myocardial infarction, unspecified
0.797 0.203 0.000
C79.2 Secondary malignant neoplasm of skin
0.797 0.203 0.000
D12.4 Descending colon
0.796 0.204 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.796 0.204 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.795 0.205 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.794 0.206 0.000
D18 Haemangioma and lymphangioma, any site
0.794 0.206 0.000
K66 Other disorders of peritoneum
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.793 0.207 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.793 0.207 0.000
I31.9 Disease of pericardium, unspecified
0.793 0.207 0.000
S40-S49 Injuries to the shoulder and upper arm
0.791 0.209 0.000
R61 Hyperhidrosis
0.790 0.210 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.789 0.211 0.000
Chapter XX External causes of morbidity and mortality
0.788 0.212 0.000
K29.4 Chronic atrophic gastritis
0.787 0.213 0.000
C51-C58 Malignant neoplasms of female genital organs
0.786 0.214 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.786 0.214 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.785 0.215 0.000
F32 Depressive episode
0.784 0.216 0.000
I45.2 Bifascicular block
0.781 0.219 0.000
K22 Other diseases of oesophagus
0.781 0.219 0.000
K29.5 Chronic gastritis, unspecified
0.780 0.220 0.000
R07.3 Other chest pain
0.779 0.221 0.000
B02 Zoster [herpes zoster]
0.779 0.221 0.000
H65.3 Chronic mucoid otitis media
0.778 0.222 0.000
Z63 Other problems related to primary support group, including family circumstances
0.778 0.222 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.777 0.223 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.776 0.224 0.000
G45.4 Transient global amnesia
0.776 0.224 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.776 0.224 0.000
B99-B99 Other infectious diseases
0.775 0.225 0.000
D12.2 Ascending colon
0.775 0.225 0.000
S01.8 Open wound of other parts of head
0.775 0.225 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.775 0.225 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.774 0.226 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.773 0.226 0.000
R14 Flatulence and related conditions
0.773 0.227 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.772 0.228 0.000
R50 Fever of unknown origin
0.771 0.229 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.770 0.230 0.000
D23.5 Skin of trunk
0.769 0.231 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.769 0.231 0.000
I45.6 Preexcitation syndrome
0.769 0.231 0.000
S80-S89 Injuries to the knee and lower leg
0.768 0.232 0.000
I35 Nonrheumatic aortic valve disorders
0.766 0.234 0.000
K70.0 Alcoholic fatty liver
0.765 0.235 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
S01.0 Open wound of scalp
0.764 0.236 0.000
K83.8 Other specified diseases of biliary tract
0.764 0.236 0.000
B35-B49 Mycoses
0.762 0.237 0.000
G57.6 Lesion of plantar nerve
0.762 0.238 0.000
G44 Other headache syndromes
0.761 0.239 0.000
D32 Benign neoplasm of meninges
0.760 0.240 0.000
K27 Peptic ulcer, site unspecified
0.760 0.240 0.000
K74 Fibrosis and cirrhosis of liver
0.760 0.240 0.000
R06.0 Dyspnoea
0.759 0.241 0.000
Z87.8 Personal history of other specified conditions
0.757 0.243 0.000
I49.8 Other specified cardiac arrhythmias
0.757 0.243 0.000
K83.0 Cholangitis
0.756 0.244 0.000
K65.9 Peritonitis, unspecified
0.755 0.245 0.000
O62 Abnormalities of forces of labour
0.755 0.245 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.754 0.246 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.753 0.247 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.753 0.247 0.000
R47.8 Other and unspecified speech disturbances
0.753 0.247 0.000
D12.7 Rectosigmoid junction
0.753 0.247 0.000
I05-I09 Chronic rheumatic heart diseases
0.751 0.249 0.000
Z88.0 Personal history of allergy to penicillin
0.751 0.249 0.000
C71 Malignant neoplasm of brain
0.750 0.250 0.000
S90-S99 Injuries to the ankle and foot
0.750 0.250 0.000
K70.4 Alcoholic hepatic failure
0.750 0.250 0.000
I86 Varicose veins of other sites
0.749 0.251 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.748 0.251 0.000
Z87.1 Personal history of diseases of the digestive system
0.747 0.253 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.747 0.253 0.000
I84.1 Internal haemorrhoids with other complications
0.746 0.254 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.745 0.255 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.745 0.255 0.000
R68 Other general symptoms and signs
0.745 0.255 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.744 0.256 0.000
R12 Heartburn
0.744 0.256 0.000
T66-T78 Other and unspecified effects of external causes
0.744 0.256 0.000
R49 Voice disturbances
0.744 0.256 0.000
N30-N39 Other diseases of urinary system
0.743 0.257 0.000
S27 Injury of other and unspecified intrathoracic organs
0.743 0.257 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.743 0.257 0.000
C80.9 Malignant neoplasm, unspecified
0.743 0.257 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.742 0.258 0.000
Z90.5 Acquired absence of kidney
0.741 0.259 0.000
D23.1 Skin of eyelid, including canthus
0.741 0.259 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.740 0.259 0.000
D12.5 Sigmoid colon
0.740 0.260 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.740 0.260 0.000
D11 Benign neoplasm of major salivary glands
0.739 0.261 0.000
G70-G73 Diseases of myoneural junction and muscle
0.738 0.262 0.000
I95 Hypotension
0.737 0.263 0.000
T86 Failure and rejection of transplanted organs and tissues
0.737 0.263 0.000
S02.4 Fracture of malar and maxillary bones
0.736 0.264 0.000
O63 Long labour
0.736 0.264 0.000
H66 Suppurative and unspecified otitis media
0.736 0.264 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.735 0.265 0.000
K72 Hepatic failure, not elsewhere classified
0.735 0.265 0.000
R17 Unspecified jaundice
0.734 0.266 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.733 0.267 0.000
Z22 Carrier of infectious disease
0.732 0.268 0.000
G90-G99 Other disorders of the nervous system
0.732 0.268 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.732 0.268 0.000
I49.9 Cardiac arrhythmia, unspecified
0.731 0.269 0.000
K85.1 Biliary acute pancreatitis
0.731 0.269 0.000
I61 Intracerebral haemorrhage
0.731 0.269 0.000
K86 Other diseases of pancreas
0.730 0.270 0.000
Z94.7 Corneal transplant status
0.729 0.270 0.000
A00-A09 Intestinal infectious diseases
0.729 0.271 0.000
K76 Other diseases of liver
0.729 0.271 0.000
Z88.5 Personal history of allergy to narcotic agent
0.727 0.273 0.000
R56 Convulsions, not elsewhere classified
0.726 0.274 0.000
Z98.0 Intestinal bypass and anastomosis status
0.726 0.274 0.000
I51.7 Cardiomegaly
0.726 0.274 0.000
K31 Other diseases of stomach and duodenum
0.726 0.274 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.726 0.274 0.000
I30 Acute pericarditis
0.725 0.274 0.000
N25-N29 Other disorders of kidney and ureter
0.724 0.276 0.000
I42 Cardiomyopathy
0.724 0.276 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.723 0.276 0.000
I34 Nonrheumatic mitral valve disorders
0.721 0.278 0.000
G50 Disorders of trigeminal nerve
0.721 0.279 0.000
T81 Complications of procedures, not elsewhere classified
0.721 0.279 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.721 0.279 0.000
Q21 Congenital malformations of cardiac septa
0.721 0.279 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.720 0.280 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.719 0.280 0.000
D13.1 Stomach
0.719 0.281 0.000
B00 Herpesviral [herpes simplex] infections
0.719 0.281 0.000
Z76 Persons encountering health services in other circumstances
0.719 0.281 0.000
S22.4 Multiple fractures of ribs
0.719 0.281 0.000
I87 Other disorders of veins
0.719 0.281 0.000
Q60-Q64 Congenital malformations of the urinary system
0.718 0.282 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.282 0.000
I49.3 Ventricular premature depolarisation
0.718 0.282 0.000
D24 Benign neoplasm of breast
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I67.9 Cerebrovascular disease, unspecified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
C78.0 Secondary malignant neoplasm of lung
0.716 0.284 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.715 0.285 0.000
S50-S59 Injuries to the elbow and forearm
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.714 0.286 0.000
H72 Perforation of tympanic membrane
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
D12.6 Colon, unspecified
0.712 0.288 0.000
H65.4 Other chronic nonsuppurative otitis media
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.711 0.289 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.711 0.289 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.711 0.289 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.711 0.289 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.711 0.289 0.000
Z82.2 Family history of deafness and hearing loss
0.711 0.289 0.000
Z82.1 Family history of blindness and visual loss
0.711 0.289 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.710 0.290 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.710 0.290 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.710 0.290 0.000
D00-D09 In situ neoplasms
0.709 0.291 0.000
R06.5 Mouth breathing
0.709 0.291 0.000
K28 Gastrojejunal ulcer
0.708 0.291 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.708 0.291 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.707 0.292 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.707 0.293 0.000
C66 Malignant neoplasm of ureter
0.707 0.293 0.000
C65 Malignant neoplasm of renal pelvis
0.707 0.293 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.707 0.293 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.707 0.293 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
I21.4 Acute subendocardial myocardial infarction
0.706 0.293 0.000
T79-T79 Certain early complications of trauma
0.706 0.294 0.000
A41 Other septicaemia
0.706 0.294 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.705 0.295 0.000
F80-F89 Disorders of psychological development
0.705 0.295 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.705 0.295 0.000
N00-N08 Glomerular diseases
0.704 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.704 0.296 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.704 0.296 0.000
J20-J22 Other acute lower respiratory infections
0.704 0.296 0.000
Z92.0 Personal history of contraception
0.704 0.296 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.703 0.297 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.703 0.297 0.000
D31 Benign neoplasm of eye and adnexa
0.703 0.297 0.000
D30 Benign neoplasm of urinary organs
0.703 0.297 0.000
D29 Benign neoplasm of male genital organs
0.703 0.297 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.703 0.297 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.703 0.297 0.000
D19 Benign neoplasm of mesothelial tissue
0.703 0.297 0.000
D16 Benign neoplasm of bone and articular cartilage
0.703 0.297 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.703 0.297 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.703 0.297 0.000
S22.3 Fracture of rib
0.703 0.297 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.702 0.298 0.000
K77 Liver disorders in diseases classified elsewhere
0.702 0.298 0.000
K73 Chronic hepatitis, not elsewhere classified
0.702 0.298 0.000
K71 Toxic liver disease
0.702 0.298 0.000
I25.5 Ischaemic cardiomyopathy
0.702 0.298 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.701 0.298 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.701 0.299 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.701 0.299 0.000
Z73 Problems related to life-management difficulty
0.701 0.299 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.699 0.301 0.000
I45.9 Conduction disorder, unspecified
0.699 0.301 0.000
I45.8 Other specified conduction disorders
0.699 0.301 0.000
I45.5 Other specified heart block
0.699 0.301 0.000
I45.4 Nonspecific intraventricular block
0.699 0.301 0.000
I45.3 Trifascicular block
0.699 0.301 0.000
I45.0 Right fascicular block
0.699 0.301 0.000
R15 Faecal incontinence
0.698 0.302 0.000
Z74 Problems related to care-provider dependency
0.697 0.303 0.000
K29.1 Other acute gastritis
0.696 0.303 0.000
F31 Bipolar affective disorder
0.696 0.304 0.000
G58 Other mononeuropathies
0.696 0.304 0.000
Z97 Presence of other devices
0.696 0.304 0.000
K65.0 Acute peritonitis
0.696 0.304 0.000
Z98.8 Other specified postsurgical states
0.696 0.304 0.000
R45 Symptoms and signs involving emotional state
0.695 0.305 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.694 0.306 0.000
I24 Other acute ischaemic heart diseases
0.694 0.306 0.000
J03 Acute tonsillitis
0.694 0.306 0.000
I89.1 Lymphangitis
0.693 0.307 0.000
O70 Perineal laceration during delivery
0.693 0.307 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.693 0.307 0.000
R07.1 Chest pain on breathing
0.693 0.307 0.000
R61.9 Hyperhidrosis, unspecified
0.693 0.307 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.693 0.307 0.000
K80.3 Calculus of bile duct with cholangitis
0.692 0.308 0.000
K80.8 Other cholelithiasis
0.692 0.308 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.691 0.308 0.000
C79.6 Secondary malignant neoplasm of ovary
0.691 0.308 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.691 0.308 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.691 0.308 0.000
K25.7 Chronic without haemorrhage or perforation
0.691 0.308 0.000
S08 Traumatic amputation of part of head
0.691 0.308 0.000
S07 Crushing injury of head
0.691 0.308 0.000
S05 Injury of eye and orbit
0.691 0.308 0.000
S04 Injury of cranial nerves
0.691 0.308 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.691 0.308 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.309 0.000
K66.0 Peritoneal adhesions
0.691 0.309 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.690 0.309 0.000
K92 Other diseases of digestive system
0.690 0.310 0.000
K22.7 Barrett's oesophagus
0.690 0.310 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.690 0.310 0.000
G41 Status epilepticus
0.690 0.310 0.000
K80.4 Calculus of bile duct with cholecystitis
0.687 0.313 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.687 0.313 0.000
R52.9 Pain, unspecified
0.687 0.313 0.000
F99-F99 Unspecified mental disorder
0.686 0.314 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.686 0.314 0.000
F70-F79 Mental retardation
0.686 0.314 0.000
F60-F69 Disorders of adult personality and behaviour
0.686 0.314 0.000
O36 Maternal care for other known or suspected foetal problems
0.686 0.314 0.000
R00.2 Palpitations
0.686 0.314 0.000
I88 Nonspecific lymphadenitis
0.685 0.314 0.000
I81 Portal vein thrombosis
0.685 0.314 0.000
K83.9 Disease of biliary tract, unspecified
0.685 0.314 0.000
K83.5 Biliary cyst
0.685 0.314 0.000
K83.4 Spasm of sphincter of Oddi
0.685 0.314 0.000
K83.3 Fistula of bile duct
0.685 0.314 0.000
K83.2 Perforation of bile duct
0.685 0.314 0.000
J06.9 Acute upper respiratory infection, unspecified
0.685 0.315 0.000
I47 Paroxysmal tachycardia
0.685 0.315 0.000
S02.6 Fracture of mandible
0.683 0.317 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.683 0.317 0.000
I74 Arterial embolism and thrombosis
0.683 0.317 0.000
S02.3 Fracture of orbital floor
0.682 0.318 0.000
S29 Other and unspecified injuries of thorax
0.682 0.318 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.682 0.318 0.000
S26 Injury of heart
0.682 0.318 0.000
S25 Injury of blood vessels of thorax
0.682 0.318 0.000
S24 Injury of nerves and spinal cord at thorax level
0.682 0.318 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.682 0.318 0.000
S21 Open wound of thorax
0.682 0.318 0.000
S20 Superficial injury of thorax
0.682 0.318 0.000
F10.2 Dependence syndrome
0.682 0.318 0.000
S02.1 Fracture of base of skull
0.682 0.318 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.681 0.319 0.000
Z72 Problems related to lifestyle
0.681 0.319 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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