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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75903686
log Bayes Factor = 17.2493
Chromosome 18   position 31,898,334  (GRCh37) Explore rs75903686 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
K80 Cholelithiasis
0.999 0.001 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.995 0.005 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.994 0.006 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.992 0.008 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.991 0.009 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.990 0.010 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.989 0.011 0.000
R10 Abdominal and pelvic pain
0.989 0.011 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.987 0.013 0.000
R10.4 Other and unspecified abdominal pain
0.982 0.018 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.982 0.018 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.980 0.020 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.977 0.023 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.974 0.026 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.973 0.027 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.967 0.033 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.967 0.033 0.000
R13 Dysphagia
0.967 0.033 0.000
I50 Heart failure
0.959 0.041 0.000
K50-K52 Noninfective enteritis and colitis
0.957 0.043 0.000
R12 Heartburn
0.956 0.044 0.000
K30 Dyspepsia
0.952 0.048 0.000
Chapter XIV Diseases of the genitourinary system
0.950 0.050 0.000
I95 Hypotension
0.943 0.057 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.942 0.058 0.000
F17.1 Harmful use
0.939 0.061 0.000
Chapter VI Diseases of the nervous system
0.937 0.063 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.936 0.064 0.000
F10.2 Dependence syndrome
0.933 0.067 0.000
Z72 Problems related to lifestyle
0.933 0.067 0.000
K52 Other non-infective gastro-enteritis and colitis
0.930 0.070 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.926 0.074 0.000
Chapter X Diseases of the respiratory system
0.923 0.077 0.000
I20 Angina pectoris
0.922 0.078 0.000
I95.1 Orthostatic hypotension
0.920 0.080 0.000
Chapter I Certain infectious and parasitic diseases
0.917 0.083 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.916 0.084 0.000
I71 Aortic aneurysm and dissection
0.913 0.087 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.913 0.087 0.000
I50.0 Congestive heart failure
0.912 0.088 0.000
N20-N23 Urolithiasis
0.911 0.089 0.000
Z90.7 Acquired absence of genital organ(s)
0.909 0.091 0.000
R10.1 Pain localised to upper abdomen
0.908 0.092 0.000
I47 Paroxysmal tachycardia
0.904 0.096 0.000
F10.1 Harmful use
0.898 0.102 0.000
Z04 Examination and observation for other reasons
0.897 0.103 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.897 0.103 0.000
G90-G99 Other disorders of the nervous system
0.895 0.105 0.000
Z93 Artificial opening status
0.893 0.107 0.000
Z87 Personal history of other diseases and conditions
0.892 0.108 0.000
F17.2 Dependence syndrome
0.892 0.108 0.000
R14 Flatulence and related conditions
0.884 0.116 0.000
Chapter XX External causes of morbidity and mortality
0.881 0.119 0.000
I20.9 Angina pectoris, unspecified
0.873 0.127 0.000
Z72.0 Tobacco use
0.871 0.129 0.000
I60-I69 Cerebrovascular diseases
0.870 0.130 0.000
N20 Calculus of kidney and ureter
0.869 0.131 0.000
J90-J94 Other diseases of pleura
0.869 0.131 0.000
J30-J39 Other diseases of upper respiratory tract
0.863 0.137 0.000
D50-D53 Nutritional anaemias
0.862 0.138 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.858 0.142 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.853 0.147 0.000
Z95.0 Presence of cardiac pacemaker
0.852 0.148 0.000
I51 Complications and ill-defined descriptions of heart disease
0.849 0.151 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.849 0.151 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.847 0.153 0.000
S70-S79 Injuries to the hip and thigh
0.846 0.154 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.844 0.156 0.000
A00-A09 Intestinal infectious diseases
0.843 0.157 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.842 0.158 0.000
I31 Other diseases of pericardium
0.841 0.159 0.000
I77 Other disorders of arteries and arterioles
0.838 0.162 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.837 0.163 0.000
J90 Pleural effusion, not elsewhere classified
0.835 0.165 0.000
N30-N39 Other diseases of urinary system
0.835 0.165 0.000
Z03.8 Observation for other suspected diseases and conditions
0.834 0.166 0.000
I73 Other peripheral vascular diseases
0.834 0.166 0.000
Z72.1 Alcohol use
0.831 0.169 0.000
R17 Unspecified jaundice
0.830 0.170 0.000
G93 Other disorders of brain
0.830 0.170 0.000
F10.0 Acute intoxication
0.829 0.171 0.000
I05-I09 Chronic rheumatic heart diseases
0.826 0.174 0.000
J30 Vasomotor and allergic rhinitis
0.825 0.175 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.825 0.175 0.000
Z97 Presence of other devices
0.824 0.176 0.000
K20 Oesophagitis
0.819 0.181 0.000
I63 Cerebral infarction
0.816 0.184 0.000
N20.1 Calculus of ureter
0.815 0.185 0.000
K22 Other diseases of oesophagus
0.814 0.186 0.000
S80-S89 Injuries to the knee and lower leg
0.814 0.186 0.000
I50.1 Left ventricular failure
0.814 0.186 0.000
Z98 Other postsurgical states
0.808 0.192 0.000
F80-F89 Disorders of psychological development
0.808 0.192 0.000
S00-S09 Injuries to the head
0.808 0.192 0.000
F41 Other anxiety disorders
0.807 0.193 0.000
K31 Other diseases of stomach and duodenum
0.807 0.193 0.000
A04 Other bacterial intestinal infections
0.803 0.197 0.000
Z90.0 Acquired absence of part of head and neck
0.796 0.204 0.000
Z02 Examination and encounter for administrative purposes
0.794 0.205 0.000
F30-F39 Mood [affective] disorders
0.792 0.208 0.000
Z03.4 Observation for suspected myocardial infarction
0.788 0.212 0.000
K80.8 Other cholelithiasis
0.786 0.214 0.000
Z90.8 Acquired absence of other organs
0.786 0.214 0.000
D51 Vitamin B12 deficiency anaemia
0.783 0.217 0.000
Z04.3 Examination and observation following other accident
0.781 0.219 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.780 0.220 0.000
K21 Gastro-oesophageal reflux disease
0.780 0.220 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.779 0.221 0.000
I51.8 Other ill-defined heart diseases
0.778 0.222 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.777 0.223 0.000
N99-N99 Other disorders of the genitourinary system
0.777 0.223 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.775 0.225 0.000
Z48 Other surgical follow-up care
0.775 0.225 0.000
I20.8 Other forms of angina pectoris
0.773 0.227 0.000
J30.1 Allergic rhinitis due to pollen
0.773 0.227 0.000
A30-A49 Other bacterial diseases
0.772 0.228 0.000
N60-N64 Disorders of breast
0.771 0.229 0.000
I35 Nonrheumatic aortic valve disorders
0.770 0.230 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.770 0.230 0.000
I22 Subsequent myocardial infarction
0.769 0.231 0.000
I78 Diseases of capillaries
0.768 0.232 0.000
I63.9 Cerebral infarction, unspecified
0.767 0.233 0.000
Z45 Adjustment and management of implanted device
0.767 0.233 0.000
Z89 Acquired absence of limb
0.766 0.234 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.765 0.235 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.765 0.235 0.000
N23 Unspecified renal colic
0.765 0.235 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.764 0.236 0.000
N25-N29 Other disorders of kidney and ureter
0.764 0.236 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.764 0.236 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.764 0.236 0.000
I47.2 Ventricular tachycardia
0.763 0.237 0.000
G91 Hydrocephalus
0.763 0.237 0.000
S72 Fracture of femur
0.762 0.238 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.762 0.238 0.000
N10-N16 Renal tubulo-interstitial diseases
0.761 0.239 0.000
Z74 Problems related to care-provider dependency
0.761 0.239 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.761 0.239 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.760 0.240 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.760 0.240 0.000
Z93.5 Cystostomy status
0.758 0.241 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.757 0.243 0.000
R11 Nausea and vomiting
0.757 0.243 0.000
I25.2 Old myocardial infarction
0.756 0.244 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.755 0.245 0.000
I95.9 Hypotension, unspecified
0.754 0.246 0.000
Z93.1 Gastrostomy status
0.753 0.247 0.000
J91 Pleural effusion in conditions classified elsewhere
0.752 0.248 0.000
F10.3 Withdrawal state
0.752 0.248 0.000
K82 Other diseases of gallbladder
0.751 0.249 0.000
I73.9 Peripheral vascular disease, unspecified
0.750 0.250 0.000
S00 Superficial injury of head
0.747 0.253 0.000
K22.8 Other specified diseases of oesophagus
0.747 0.253 0.000
Z90.5 Acquired absence of kidney
0.747 0.253 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.746 0.254 0.000
J95-J99 Other diseases of the respiratory system
0.746 0.254 0.000
F41.2 Mixed anxiety and depressive disorder
0.746 0.254 0.000
K27 Peptic ulcer, site unspecified
0.744 0.256 0.000
G93.3 Postviral fatigue syndrome
0.744 0.256 0.000
I25.5 Ischaemic cardiomyopathy
0.743 0.257 0.000
I42 Cardiomyopathy
0.742 0.258 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.741 0.259 0.000
K70-K77 Diseases of liver
0.740 0.260 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.739 0.261 0.000
N32 Other disorders of bladder
0.737 0.263 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.737 0.263 0.000
F43 Reaction to severe stress, and adjustment disorders
0.736 0.263 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.735 0.265 0.000
Q00-Q07 Congenital malformations of the nervous system
0.733 0.266 0.000
Z04.8 Examination and observation for other specified reasons
0.733 0.267 0.000
I47.1 Supraventricular tachycardia
0.733 0.267 0.000
Z03.3 Observation for suspected nervous system disorder
0.732 0.268 0.000
I70 Atherosclerosis
0.732 0.268 0.000
Z95.3 Presence of xenogenic heart valve
0.730 0.270 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.729 0.271 0.000
J39 Other diseases of upper respiratory tract
0.728 0.272 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.727 0.273 0.000
I50.9 Heart failure, unspecified
0.726 0.274 0.000
R30-R39 Symptoms and signs involving the urinary system
0.725 0.275 0.000
Z60 Problems related to social environment
0.721 0.279 0.000
D50 Iron deficiency anaemia
0.721 0.279 0.000
N34 Urethritis and urethral syndrome
0.721 0.279 0.000
I31.3 Pericardial effusion (noninflammatory)
0.720 0.280 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.719 0.280 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.719 0.281 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.719 0.281 0.000
K86 Other diseases of pancreas
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
K80.3 Calculus of bile duct with cholangitis
0.717 0.283 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.716 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.715 0.285 0.000
N20.0 Calculus of kidney
0.714 0.286 0.000
K55-K64 Other diseases of intestines
0.713 0.287 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.3 Aneurysm of heart
0.713 0.287 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.287 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.712 0.288 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.710 0.289 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
N00-N08 Glomerular diseases
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.710 0.290 0.000
I48 Atrial fibrillation and flutter
0.710 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.710 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.710 0.290 0.000
I40 Acute myocarditis
0.710 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.710 0.290 0.000
I37 Pulmonary valve disorders
0.710 0.290 0.000
I36 Nonrheumatic tricuspid valve disorders
0.710 0.290 0.000
I33 Acute and subacute endocarditis
0.710 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.710 0.290 0.000
I30 Acute pericarditis
0.710 0.290 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.709 0.291 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.709 0.291 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.709 0.291 0.000
Z04.9 Examination and observation for unspecified reason
0.708 0.292 0.000
F10.9 Unspecified mental and behavioural disorder
0.708 0.292 0.000
F10.8 Other mental and behavioural disorders
0.708 0.292 0.000
F10.7 Residual and late-onset psychotic disorder
0.708 0.292 0.000
F10.6 Amnesic syndrome
0.708 0.292 0.000
F10.5 Psychotic disorder
0.708 0.292 0.000
F10.4 Withdrawal state with delirium
0.708 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
W20-W49 Exposure to inanimate mechanical forces
0.706 0.294 0.000
I74 Arterial embolism and thrombosis
0.705 0.295 0.000
Chapter XXII Codes for special purposes
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.704 0.296 0.000
I72 Other aneurysm
0.704 0.296 0.000
Z73 Problems related to life-management difficulty
0.704 0.296 0.000
F17.9 Unspecified mental and behavioural disorder
0.703 0.297 0.000
F17.8 Other mental and behavioural disorders
0.703 0.297 0.000
F17.7 Residual and late-onset psychotic disorder
0.703 0.297 0.000
F17.6 Amnesic syndrome
0.703 0.297 0.000
F17.5 Psychotic disorder
0.703 0.297 0.000
F17.4 Withdrawal state with delirium
0.703 0.297 0.000
F17.3 Withdrawal state
0.703 0.297 0.000
F17.0 Acute intoxication
0.703 0.297 0.000
Z48.9 Surgical follow-up care, unspecified
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
I08 Multiple valve diseases
0.701 0.298 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.701 0.299 0.000
Z99.8 Dependence on other enabling machines and devices
0.700 0.300 0.000
N35 Urethral stricture
0.700 0.300 0.000
Z53.8 Procedure not carried out for other reasons
0.700 0.300 0.000
Z10 Routine general health check-up of defined subpopulation
0.698 0.301 0.000
K28 Gastrojejunal ulcer
0.698 0.302 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.698 0.302 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.697 0.303 0.000
N62 Hypertrophy of breast
0.696 0.304 0.000
I77.0 Arteriovenous fistula, acquired
0.694 0.306 0.000
K31.8 Other specified diseases of stomach and duodenum
0.694 0.306 0.000
I45 Other conduction disorders
0.693 0.307 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.693 0.307 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.693 0.307 0.000
I99 Other and unspecified disorders of circulatory system
0.693 0.307 0.000
Z76 Persons encountering health services in other circumstances
0.693 0.307 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.693 0.307 0.000
R47-R49 Symptoms and signs involving speech and voice
0.692 0.308 0.000
K83 Other diseases of biliary tract
0.688 0.312 0.000
I20.1 Angina pectoris with documented spasm
0.687 0.313 0.000
K85 Acute pancreatitis
0.687 0.313 0.000
Z98.1 Arthrodesis status
0.686 0.314 0.000
K80.4 Calculus of bile duct with cholecystitis
0.684 0.316 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.684 0.316 0.000
Z83 Family history of other specific disorders
0.684 0.316 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
I60 Subarachnoid haemorrhage
0.684 0.316 0.000
Z48.8 Other specified surgical follow-up care
0.683 0.317 0.000
N32.9 Bladder disorder, unspecified
0.683 0.317 0.000
R35 Polyuria
0.681 0.319 0.000
Z95.1 Presence of aortocoronary bypass graft
0.680 0.320 0.000
S72.0 Fracture of neck of femur
0.679 0.321 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.678 0.322 0.000
A04.5 Campylobacter enteritis
0.678 0.322 0.000
Chapter VIII Diseases of the ear and mastoid process
0.677 0.322 0.000
I95.8 Other hypotension
0.676 0.324 0.000
I95.2 Hypotension due to drugs
0.676 0.324 0.000
I95.0 Idiopathic hypotension
0.676 0.324 0.000
J34 Other disorders of nose and nasal sinuses
0.676 0.324 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.676 0.324 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.676 0.324 0.000
Z03.0 Observation for suspected tuberculosis
0.676 0.324 0.000
A04.8 Other specified bacterial intestinal infections
0.675 0.325 0.000
S00.8 Superficial injury of other parts of head
0.674 0.326 0.000
M80-M85 Disorders of bone density and structure
0.674 0.326 0.000
Z45.8 Adjustment and management of other implanted devices
0.674 0.326 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.673 0.327 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.673 0.327 0.000
I38 Endocarditis, valve unspecified
0.672 0.327 0.000
K51 Ulcerative colitis
0.673 0.327 0.000
G70-G73 Diseases of myoneural junction and muscle
0.672 0.328 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
G93.4 Encephalopathy, unspecified
0.672 0.328 0.000
T79-T79 Certain early complications of trauma
0.671 0.329 0.000
T33-T35 Frostbite
0.671 0.329 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.671 0.329 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.671 0.329 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.671 0.329 0.000
T00-T07 Injuries involving multiple body regions
0.671 0.329 0.000
S10-S19 Injuries to the neck
0.671 0.329 0.000
F81 Specific developmental disorders of scholastic skills
0.670 0.330 0.000
Z90.2 Acquired absence of lung [part of]
0.670 0.330 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.669 0.331 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.669 0.331 0.000
Z72.9 Problem related to lifestyle, unspecified
0.669 0.331 0.000
Z72.8 Other problems related to lifestyle
0.669 0.331 0.000
Z72.6 Gambling and betting
0.669 0.331 0.000
Z72.5 High-risk sexual behaviour
0.669 0.331 0.000
Z72.4 Inappropriate diet and eating habits
0.669 0.331 0.000
Z72.3 Lack of physical exercise
0.669 0.331 0.000
Z72.2 Drug use
0.669 0.331 0.000
I77.1 Stricture of artery
0.669 0.331 0.000
V10-V19 Pedal cyclist injured in transport accident
0.669 0.331 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.669 0.331 0.000
Z93.3 Colostomy status
0.668 0.332 0.000
G91.9 Hydrocephalus, unspecified
0.668 0.332 0.000
K52.3 Indeterminate colitis
0.667 0.333 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.667 0.333 0.000
K52.1 Toxic gastro-enteritis and colitis
0.667 0.333 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.667 0.333 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.667 0.333 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.666 0.334 0.000
Z02.8 Other examinations for administrative purposes
0.666 0.334 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.665 0.335 0.000
K59 Other functional intestinal disorders
0.664 0.336 0.000
D55-D59 Haemolytic anaemias
0.664 0.336 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.662 0.337 0.000
D80-D89 Certain disorders involving the immune mechanism
0.663 0.337 0.000
Z41 Procedures for purposes other than remedying health state
0.662 0.337 0.000
S70 Superficial injury of hip and thigh
0.662 0.338 0.000
J30.4 Allergic rhinitis, unspecified
0.662 0.338 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.660 0.340 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.660 0.340 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.659 0.341 0.000
Z63 Other problems related to primary support group, including family circumstances
0.659 0.341 0.000
B99-B99 Other infectious diseases
0.658 0.342 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.658 0.342 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.658 0.342 0.000
B65-B83 Helminthiases
0.658 0.342 0.000
B50-B64 Protozoal diseases
0.658 0.342 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.658 0.342 0.000
B15-B19 Viral hepatitis
0.658 0.342 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.658 0.342 0.000
A80-A89 Viral infections of the central nervous system
0.658 0.342 0.000
A75-A79 Rickettsioses
0.658 0.342 0.000
A70-A74 Other diseases caused by chlamydiae
0.658 0.342 0.000
A65-A69 Other spirochaetal diseases
0.658 0.342 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.658 0.342 0.000
A20-A28 Certain zoonotic bacterial diseases
0.658 0.342 0.000
A15-A19 Tuberculosis
0.658 0.342 0.000
Z99.1 Dependence on respirator
0.658 0.342 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.657 0.343 0.000
I25.1 Atherosclerotic heart disease
0.656 0.344 0.000
R10.0 Acute abdomen
0.656 0.344 0.000
Q05 Spina bifida
0.656 0.344 0.000
N20.2 Calculus of kidney with calculus of ureter
0.655 0.345 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.655 0.345 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.655 0.345 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.655 0.345 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.655 0.345 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.655 0.345 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.655 0.345 0.000
I71.0 Dissection of aorta [any part]
0.655 0.345 0.000
B35-B49 Mycoses
0.655 0.345 0.000
K50 Crohn's disease [regional enteritis]
0.654 0.346 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.653 0.346 0.000
I62 Other nontraumatic intracranial haemorrhage
0.653 0.347 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.653 0.347 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.653 0.347 0.000
J00-J06 Acute upper respiratory infections
0.652 0.348 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.652 0.348 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.652 0.348 0.000
R30 Pain associated with micturition
0.652 0.348 0.000
S20-S29 Injuries to the thorax
0.652 0.348 0.000
D50.9 Iron deficiency anaemia, unspecified
0.652 0.348 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.651 0.348 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.650 0.350 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.649 0.351 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.649 0.351 0.000
J30.3 Other allergic rhinitis
0.648 0.352 0.000
I47.0 Reentry ventricular arrhythmia
0.648 0.352 0.000
B07 Viral warts
0.648 0.352 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.645 0.355 0.000
J36 Peritonsillar abscess
0.645 0.355 0.000
Z75 Problems related to medical facilities and other health care
0.644 0.356 0.000
I46 Cardiac arrest
0.643 0.357 0.000
Z04.6 General psychiatric examination, requested by authority
0.643 0.357 0.000
Z04.5 Examination and observation following other inflicted injury
0.643 0.357 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.643 0.357 0.000
Z04.2 Examination and observation following work accident
0.643 0.357 0.000
Z04.1 Examination and observation following transport accident
0.643 0.357 0.000
Z04.0 Blood-alcohol and blood-drug test
0.643 0.357 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.643 0.357 0.000
F48 Other neurotic disorders
0.643 0.357 0.000
F44 Dissociative [conversion] disorders
0.643 0.357 0.000
F42 Obsessive-compulsive disorder
0.643 0.357 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.642 0.357 0.000
F41.9 Anxiety disorder, unspecified
0.642 0.358 0.000
Z03.1 Observation for suspected malignant neoplasm
0.642 0.358 0.000
K31.5 Obstruction of duodenum
0.642 0.358 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
G96 Other disorders of central nervous system
0.642 0.358 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.642 0.358 0.000
G90 Disorders of autonomic nervous system
0.642 0.358 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
G92 Toxic encephalopathy
0.642 0.358 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.641 0.358 0.000
I24 Other acute ischaemic heart diseases
0.641 0.358 0.000
A41 Other septicaemia
0.641 0.359 0.000
Z93.9 Artificial opening status, unspecified
0.640 0.360 0.000
Z93.8 Other artificial opening status
0.640 0.360 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.640 0.360 0.000
Z93.0 Tracheostomy status
0.640 0.360 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.640 0.360 0.000
R10.2 Pelvic and perineal pain
0.640 0.360 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.640 0.360 0.000
G93.9 Disorder of brain, unspecified
0.640 0.360 0.000
N34.2 Other urethritis
0.639 0.361 0.000
D69 Purpura and other haemorrhagic conditions
0.637 0.363 0.000
K22.9 Disease of oesophagus, unspecified
0.637 0.363 0.000
K65-K67 Diseases of peritoneum
0.635 0.364 0.000
I44 Atrioventricular and left bundle-branch block
0.635 0.365 0.000
T66-T78 Other and unspecified effects of external causes
0.635 0.365 0.000
K35-K38 Diseases of appendix
0.635 0.365 0.000
Z93.6 Other artificial openings of urinary tract status
0.634 0.366 0.000
M05-M14 Inflammatory polyarthropathies
0.634 0.366 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.634 0.366 0.000
Z43 Attention to artificial openings
0.634 0.366 0.000
I31.9 Disease of pericardium, unspecified
0.633 0.367 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.633 0.367 0.000
Y35-Y36 Legal intervention and operations of war
0.632 0.368 0.000
Y10-Y34 Event of undetermined intent
0.632 0.368 0.000
Y00-Y09 Assault
0.632 0.368 0.000
X85-X99 Assault
0.632 0.368 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.632 0.368 0.000
X50-X57 Overexertion, travel and privation
0.632 0.368 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.632 0.368 0.000
X30-X39 Exposure to forces of nature
0.632 0.368 0.000
X20-X29 Contact with venomous animals and plants
0.632 0.368 0.000
X10-X19 Contact with heat and hot substances
0.632 0.368 0.000
X00-X09 Exposure to smoke, fire and flames
0.632 0.368 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.632 0.368 0.000
W75-W84 Other accidental threats to breathing
0.632 0.368 0.000
W65-W74 Accidental drowning and submersion
0.632 0.368 0.000
W50-W64 Exposure to animate mechanical forces
0.632 0.368 0.000
V98-V99 Other and unspecified transport accidents
0.632 0.368 0.000
V95-V97 Air and space transport accidents
0.632 0.368 0.000
V90-V94 Water transport accidents
0.632 0.368 0.000
V80-V89 Other land transport accidents
0.632 0.368 0.000
V70-V79 Bus occupant injured in transport accident
0.632 0.368 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.632 0.368 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.632 0.368 0.000
V40-V49 Car occupant injured in transport accident
0.632 0.368 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.632 0.368 0.000
V20-V29 Motorcycle rider injured in transport accident
0.632 0.368 0.000
V01-V09 Pedestrian injured in transport accident
0.632 0.368 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.632 0.368 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.631 0.369 0.000
Z60.2 Living alone
0.631 0.369 0.000
Z98.8 Other specified postsurgical states
0.631 0.369 0.000
F45 Somatoform disorders
0.630 0.369 0.000
Z99.2 Dependence on renal dialysis
0.630 0.370 0.000
J60-J70 Lung diseases due to external agents
0.629 0.371 0.000
Z97.8 Presence of other specified devices
0.628 0.372 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.627 0.373 0.000
F31 Bipolar affective disorder
0.626 0.374 0.000
G35 Multiple sclerosis
0.625 0.375 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.625 0.375 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.624 0.376 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.624 0.376 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.624 0.376 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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