TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs76069769
log Bayes Factor = 20.8608
Chromosome 2   position 114,598,449  (GRCh37) Explore rs76069769 on Ensembl!
Variant rs76069769 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.996 0.004 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
S60-S69 Injuries to the wrist and hand
0.992 0.008 0.000
E70-E90 Metabolic disorders
0.991 0.009 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.985 0.015 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.983 0.017 0.000
R50-R69 General symptoms and signs
0.983 0.017 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.980 0.020 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
H35 Other retinal disorders
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.978 0.022 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.975 0.025 0.000
R07 Pain in throat and chest
0.973 0.027 0.000
S00-S09 Injuries to the head
0.972 0.028 0.000
F30-F39 Mood [affective] disorders
0.972 0.028 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.972 0.028 0.000
E78.5 Hyperlipidaemia, unspecified
0.972 0.028 0.000
R30-R39 Symptoms and signs involving the urinary system
0.970 0.030 0.000
M23 Internal derangement of knee
0.966 0.034 0.000
R20 Disturbances of skin sensation
0.964 0.036 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.964 0.036 0.000
G35 Multiple sclerosis
0.958 0.042 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.957 0.043 0.000
R07.4 Chest pain, unspecified
0.956 0.044 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.949 0.051 0.000
E86 Volume depletion
0.949 0.051 0.000
M05-M14 Inflammatory polyarthropathies
0.943 0.057 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.941 0.059 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.941 0.059 0.000
R06 Abnormalities of breathing
0.933 0.067 0.000
F31 Bipolar affective disorder
0.931 0.069 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
R55 Syncope and collapse
0.927 0.073 0.000
H33 Retinal detachments and breaks
0.925 0.075 0.000
S80-S89 Injuries to the knee and lower leg
0.925 0.075 0.000
M06 Other rheumatoid arthritis
0.918 0.082 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.914 0.086 0.000
H35.3 Degeneration of macula and posterior pole
0.914 0.086 0.000
R39 Other symptoms and signs involving the urinary system
0.914 0.086 0.000
R25 Abnormal involuntary movements
0.908 0.092 0.000
H43-H45 Disorders of vitreous body and globe
0.906 0.094 0.000
S62 Fracture at wrist and hand level
0.905 0.095 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.903 0.097 0.000
R52 Pain, not elsewhere classified
0.902 0.098 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.899 0.101 0.000
M06.9 Rheumatoid arthritis, unspecified
0.899 0.101 0.000
E20-E35 Disorders of other endocrine glands
0.897 0.103 0.000
R30 Pain associated with micturition
0.896 0.104 0.000
E10-E14 Diabetes mellitus
0.895 0.105 0.000
M45-M49 Spondylopathies
0.894 0.106 0.000
R53 Malaise and fatigue
0.892 0.108 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.889 0.111 0.000
R20.2 Paraesthesia of skin
0.887 0.113 0.000
R06.5 Mouth breathing
0.887 0.113 0.000
S40-S49 Injuries to the shoulder and upper arm
0.887 0.113 0.000
M80-M85 Disorders of bone density and structure
0.886 0.114 0.000
R23 Other skin changes
0.886 0.114 0.000
F33 Recurrent depressive disorder
0.884 0.116 0.000
S90-S99 Injuries to the ankle and foot
0.882 0.118 0.000
G90-G99 Other disorders of the nervous system
0.881 0.119 0.000
T88.4 Failed or difficult intubation
0.875 0.125 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.875 0.125 0.000
R51 Headache
0.874 0.126 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.871 0.129 0.000
R07.2 Precordial pain
0.870 0.130 0.000
M50-M54 Other dorsopathies
0.867 0.133 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.866 0.134 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.865 0.135 0.000
M23.3 Other meniscus derangements
0.865 0.135 0.000
F31.9 Bipolar affective disorder, unspecified
0.864 0.136 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.862 0.138 0.000
S61 Open wound of wrist and hand
0.861 0.139 0.000
G30-G32 Other degenerative diseases of the nervous system
0.860 0.140 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.854 0.146 0.000
H53-H54 Visual disturbances and blindness
0.853 0.147 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.852 0.148 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.851 0.149 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.849 0.151 0.000
R47-R49 Symptoms and signs involving speech and voice
0.848 0.152 0.000
H36 Retinal disorders in diseases classified elsewhere
0.847 0.153 0.000
H33.5 Other retinal detachments
0.847 0.153 0.000
R40 Somnolence, stupor and coma
0.846 0.154 0.000
H43 Disorders of vitreous body
0.846 0.154 0.000
M22 Disorders of patella
0.845 0.155 0.000
R30.0 Dysuria
0.843 0.157 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.842 0.158 0.000
R01 Cardiac murmurs and other cardiac sounds
0.840 0.160 0.000
S81 Open wound of lower leg
0.839 0.161 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.839 0.161 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.837 0.163 0.000
Chapter VIII Diseases of the ear and mastoid process
0.835 0.165 0.000
H35.0 Background retinopathy and retinal vascular changes
0.833 0.167 0.000
T66-T78 Other and unspecified effects of external causes
0.830 0.170 0.000
R05 Cough
0.829 0.171 0.000
S06 Intracranial injury
0.828 0.172 0.000
S05 Injury of eye and orbit
0.828 0.172 0.000
Q60-Q64 Congenital malformations of the urinary system
0.827 0.173 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.827 0.173 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.827 0.173 0.000
M24 Other specific joint derangements
0.826 0.174 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.826 0.174 0.000
R45 Symptoms and signs involving emotional state
0.825 0.175 0.000
S70-S79 Injuries to the hip and thigh
0.823 0.177 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.823 0.177 0.000
R52.2 Other chronic pain
0.823 0.177 0.000
S62.3 Fracture of other metacarpal bone
0.819 0.181 0.000
M65-M68 Disorders of synovium and tendon
0.818 0.182 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.818 0.182 0.000
R25.1 Tremor, unspecified
0.810 0.190 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.809 0.191 0.000
M40-M43 Deforming dorsopathies
0.808 0.192 0.000
S63.6 Sprain and strain of finger(s)
0.807 0.193 0.000
S09 Other and unspecified injuries of head
0.807 0.193 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.807 0.193 0.000
R54 Senility
0.805 0.195 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.804 0.196 0.000
M54 Dorsalgia
0.803 0.197 0.000
R06.8 Other and unspecified abnormalities of breathing
0.798 0.202 0.000
H31 Other disorders of choroid
0.798 0.202 0.000
G93 Other disorders of brain
0.796 0.204 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.795 0.205 0.000
H33.2 Serous retinal detachment
0.795 0.205 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.794 0.206 0.000
W20-W49 Exposure to inanimate mechanical forces
0.793 0.207 0.000
R46 Symptoms and signs involving appearance and behaviour
0.793 0.207 0.000
H43.1 Vitreous haemorrhage
0.792 0.208 0.000
Y40 Systemic antibiotics
0.792 0.208 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.791 0.208 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.790 0.210 0.000
Q00-Q07 Congenital malformations of the nervous system
0.789 0.211 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.789 0.211 0.000
H35.6 Retinal haemorrhage
0.789 0.211 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.787 0.213 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.786 0.214 0.000
Y57 Other and unspecified drugs and medicaments
0.786 0.214 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.785 0.215 0.000
H35.9 Retinal disorder, unspecified
0.784 0.216 0.000
S61.8 Open wound of other parts of wrist and hand
0.784 0.216 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.783 0.217 0.000
Chapter XXII Codes for special purposes
0.782 0.218 0.000
R43 Disturbances of smell and taste
0.780 0.220 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
R57 Shock, not elsewhere classified
0.779 0.221 0.000
F33.9 Recurrent depressive disorder, unspecified
0.779 0.221 0.000
E83 Disorders of mineral metabolism
0.778 0.222 0.000
E11 Non-insulin-dependent diabetes mellitus
0.777 0.223 0.000
R42 Dizziness and giddiness
0.776 0.224 0.000
R35 Polyuria
0.775 0.225 0.000
F99-F99 Unspecified mental disorder
0.774 0.226 0.000
S80 Superficial injury of lower leg
0.773 0.227 0.000
S64 Injury of nerves at wrist and hand level
0.773 0.227 0.000
R21 Rash and other nonspecific skin eruption
0.773 0.227 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.773 0.227 0.000
G40-G47 Episodic and paroxysmal disorders
0.773 0.227 0.000
G20-G26 Extrapyramidal and movement disorders
0.772 0.228 0.000
M86-M90 Other osteopathies
0.772 0.228 0.000
F60-F69 Disorders of adult personality and behaviour
0.772 0.228 0.000
R34 Anuria and oliguria
0.772 0.228 0.000
S42 Fracture of shoulder and upper arm
0.771 0.229 0.000
S60 Superficial injury of wrist and hand
0.770 0.229 0.000
V40-V49 Car occupant injured in transport accident
0.769 0.231 0.000
R47 Speech disturbances, not elsewhere classified
0.769 0.231 0.000
S02 Fracture of skull and facial bones
0.769 0.231 0.000
R02 Gangrene, not elsewhere classified
0.768 0.232 0.000
R50 Fever of unknown origin
0.768 0.232 0.000
M47 Spondylosis
0.767 0.233 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.767 0.233 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.767 0.233 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.766 0.234 0.000
S01 Open wound of head
0.766 0.234 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.766 0.234 0.000
F34 Persistent mood [affective] disorders
0.765 0.235 0.000
E78.2 Mixed hyperlipidaemia
0.765 0.235 0.000
M30 Polyarteritis nodosa and related conditions
0.764 0.236 0.000
X20-X29 Contact with venomous animals and plants
0.764 0.236 0.000
S62.5 Fracture of thumb
0.764 0.236 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.763 0.237 0.000
M84 Disorders of continuity of bone
0.761 0.239 0.000
R23.1 Pallor
0.760 0.240 0.000
R60 Oedema, not elsewhere classified
0.758 0.242 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.242 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.757 0.243 0.000
R41.0 Disorientation, unspecified
0.757 0.243 0.000
M54.5 Low back pain
0.756 0.244 0.000
R09.1 Pleurisy
0.754 0.246 0.000
M34 Systemic sclerosis
0.754 0.246 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.753 0.246 0.000
S00 Superficial injury of head
0.753 0.247 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
M11 Other crystal arthropathies
0.751 0.248 0.000
S81.0 Open wound of knee
0.751 0.249 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.751 0.249 0.000
M21 Other acquired deformities of limbs
0.751 0.249 0.000
E14 Unspecified diabetes mellitus
0.751 0.249 0.000
Q80-Q89 Other congenital malformations
0.750 0.250 0.000
Y43 Primarily systemic agents
0.749 0.251 0.000
M48 Other spondylopathies
0.748 0.252 0.000
T86 Failure and rejection of transplanted organs and tissues
0.748 0.252 0.000
R25.2 Cramp and spasm
0.746 0.254 0.000
R06.6 Hiccough
0.746 0.254 0.000
M00-M03 Infectious arthropathies
0.746 0.254 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.745 0.255 0.000
Y00-Y09 Assault
0.744 0.256 0.000
R26 Abnormalities of gait and mobility
0.743 0.257 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.742 0.258 0.000
F30 Manic episode
0.742 0.258 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.742 0.258 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.741 0.259 0.000
H36.0 Diabetic retinopathy
0.741 0.259 0.000
H40-H42 Glaucoma
0.741 0.259 0.000
M91-M94 Chondropathies
0.741 0.259 0.000
S61.1 Open wound of finger(s) with damage to nail
0.740 0.260 0.000
T92 Sequelae of injuries of upper limb
0.740 0.260 0.000
F43 Reaction to severe stress, and adjustment disorders
0.739 0.261 0.000
H35.7 Separation of retinal layers
0.739 0.261 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.738 0.262 0.000
H35.5 Hereditary retinal dystrophy
0.736 0.264 0.000
S69 Other and unspecified injuries of wrist and hand
0.735 0.264 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.734 0.266 0.000
M54.56 Low back pain (Lumbar region)
0.734 0.266 0.000
H55-H59 Other disorders of eye and adnexa
0.734 0.266 0.000
M23.8 Other internal derangements of knee
0.734 0.266 0.000
E23 Hypofunction and other disorders of pituitary gland
0.733 0.267 0.000
R41.2 Retrograde amnesia
0.732 0.268 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.732 0.268 0.000
R40.0 Somnolence
0.731 0.269 0.000
R27 Other lack of coordination
0.731 0.269 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.728 0.272 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.727 0.273 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
X60-X84 Intentional self-harm
0.727 0.273 0.000
V20-V29 Motorcycle rider injured in transport accident
0.726 0.273 0.000
R23.3 Spontaneous ecchymoses
0.726 0.273 0.000
F03 Unspecified dementia
0.726 0.274 0.000
S92 Fracture of foot, except ankle
0.725 0.275 0.000
H35.4 Peripheral retinal degeneration
0.725 0.275 0.000
H10-H13 Disorders of conjunctiva
0.724 0.276 0.000
G37 Other demyelinating diseases of central nervous system
0.721 0.279 0.000
R52.9 Pain, unspecified
0.721 0.279 0.000
M81 Osteoporosis without pathological fracture
0.721 0.279 0.000
T93 Sequelae of injuries of lower limb
0.720 0.280 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.720 0.280 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.720 0.280 0.000
S90 Superficial injury of ankle and foot
0.718 0.282 0.000
R01.1 Cardiac murmur, unspecified
0.718 0.282 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.718 0.282 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.718 0.282 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
S86 Injury of muscle and tendon at lower leg level
0.717 0.283 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.716 0.284 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.715 0.285 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.714 0.286 0.000
H30 Chorioretinal inflammation
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
H90-H95 Other disorders of ear
0.712 0.288 0.000
Y42.5 Other oestrogens and progestogens
0.712 0.288 0.000
S67 Crushing injury of wrist and hand
0.711 0.288 0.000
S65 Injury of blood vessels at wrist and hand level
0.711 0.288 0.000
E85 Amyloidosis
0.710 0.290 0.000
E84 Cystic fibrosis
0.710 0.290 0.000
E79 Disorders of purine and pyrimidine metabolism
0.710 0.290 0.000
E77 Disorders of glycoprotein metabolism
0.710 0.290 0.000
E76 Disorders of glycosaminoglycan metabolism
0.710 0.290 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.710 0.290 0.000
E74 Other disorders of carbohydrate metabolism
0.710 0.290 0.000
E73 Lactose intolerance
0.710 0.290 0.000
E72 Other disorders of amino-acid metabolism
0.710 0.290 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.710 0.290 0.000
E70 Disorders of aromatic amino-acid metabolism
0.710 0.290 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.710 0.290 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.710 0.290 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
E22 Hyperfunction of pituitary gland
0.708 0.292 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.707 0.292 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.707 0.293 0.000
H52 Disorders of refraction and accommodation
0.707 0.293 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.707 0.293 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.705 0.295 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.705 0.295 0.000
R62 Lack of expected normal physiological development
0.705 0.295 0.000
R64 Cachexia
0.705 0.295 0.000
R58 Haemorrhage, not elsewhere classified
0.705 0.295 0.000
F20 Schizophrenia
0.704 0.296 0.000
H54 Blindness and low vision
0.704 0.296 0.000
E78.6 Lipoprotein deficiency
0.703 0.297 0.000
E78.4 Other hyperlipidaemia
0.703 0.297 0.000
E78.3 Hyperchylomicronaemia
0.703 0.297 0.000
E78.1 Pure hyperglyceridaemia
0.703 0.297 0.000
Chapter II Neoplasms
0.703 0.297 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.298 0.000
M33 Dermatopolymyositis
0.701 0.298 0.000
M32 Systemic lupus erythematosus
0.701 0.298 0.000
H35.2 Other proliferative retinopathy
0.701 0.299 0.000
H35.1 Retinopathy of prematurity
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
W50-W64 Exposure to animate mechanical forces
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
M54.2 Cervicalgia
0.701 0.299 0.000
T78 Adverse effects, not elsewhere classified
0.700 0.300 0.000
G36 Other acute disseminated demyelination
0.699 0.301 0.000
M24.1 Other articular cartilage disorders
0.698 0.302 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.697 0.303 0.000
S08 Traumatic amputation of part of head
0.697 0.303 0.000
S07 Crushing injury of head
0.697 0.303 0.000
S04 Injury of cranial nerves
0.697 0.303 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.697 0.303 0.000
F38 Other mood [affective] disorders
0.697 0.303 0.000
F39 Unspecified mood [affective] disorder
0.697 0.303 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.697 0.303 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.697 0.303 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.697 0.303 0.000
E78.8 Other disorders of lipoprotein metabolism
0.696 0.304 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.695 0.305 0.000
R36 Urethral discharge
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
Q63 Other congenital malformations of kidney
0.694 0.306 0.000
M23.9 Internal derangement of knee, unspecified
0.693 0.307 0.000
M23.1 Discoid meniscus (congenital)
0.693 0.307 0.000
M23.0 Cystic meniscus
0.693 0.307 0.000
T51 Toxic effect of alcohol
0.692 0.308 0.000
Chapter I Certain infectious and parasitic diseases
0.692 0.308 0.000
F29 Unspecified nonorganic psychosis
0.692 0.308 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.691 0.309 0.000
R20.3 Hyperaesthesia
0.691 0.309 0.000
R20.1 Hypoaesthesia of skin
0.691 0.309 0.000
R20.0 Anaesthesia of skin
0.691 0.309 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.691 0.309 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.691 0.309 0.000
Q35-Q37 Cleft lip and cleft palate
0.691 0.309 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.309 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.691 0.309 0.000
R32 Unspecified urinary incontinence
0.691 0.309 0.000
M47.8 Other spondylosis
0.691 0.309 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.690 0.310 0.000
S89 Other and unspecified injuries of lower leg
0.689 0.310 0.000
S05.8 Other injuries of eye and orbit
0.690 0.310 0.000
R61 Hyperhidrosis
0.689 0.311 0.000
Y42.7 Androgens and anabolic congeners
0.689 0.311 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.688 0.312 0.000
S06.9 Intracranial injury, unspecified
0.688 0.312 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.688 0.312 0.000
G93.3 Postviral fatigue syndrome
0.688 0.312 0.000
Y86 Sequelae of other accidents
0.688 0.312 0.000
M23.5 Chronic instability of knee
0.686 0.314 0.000
G90 Disorders of autonomic nervous system
0.685 0.314 0.000
G43 Migraine
0.685 0.315 0.000
S72 Fracture of femur
0.685 0.315 0.000
H53 Visual disturbances
0.684 0.316 0.000
F80-F89 Disorders of psychological development
0.684 0.316 0.000
M22.4 Chondromalacia patellae
0.683 0.317 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.682 0.318 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.681 0.318 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.681 0.319 0.000
Y59 Other and unspecified vaccines and biological substances
0.681 0.319 0.000
Y58 Bacterial vaccines
0.681 0.319 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.681 0.319 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.681 0.319 0.000
Y48 Anaesthetics and therapeutic gases
0.681 0.319 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.681 0.319 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.681 0.319 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.680 0.320 0.000
W00-W19 Falls
0.680 0.320 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.679 0.321 0.000
S91 Open wound of ankle and foot
0.678 0.321 0.000
S81.8 Open wound of other parts of lower leg
0.678 0.322 0.000
M14 Arthropathies in other diseases classified elsewhere
0.676 0.324 0.000
M12 Other specific arthropathies
0.676 0.324 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.676 0.324 0.000
M08 Juvenile arthritis
0.676 0.324 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.676 0.324 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.675 0.325 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.674 0.326 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.674 0.326 0.000
M06.0 Seronegative rheumatoid arthritis
0.673 0.327 0.000
R45.8 Other symptoms and signs involving emotional state
0.672 0.328 0.000
G62 Other polyneuropathies
0.671 0.329 0.000
M31 Other necrotising vasculopathies
0.671 0.329 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.671 0.329 0.000
R07.1 Chest pain on breathing
0.670 0.330 0.000
R80 Isolated proteinuria
0.670 0.330 0.000
H80-H83 Diseases of inner ear
0.670 0.330 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.669 0.331 0.000
G81 Hemiplegia
0.669 0.331 0.000
R06.7 Sneezing
0.669 0.331 0.000
R06.3 Periodic breathing
0.669 0.331 0.000
R06.1 Stridor
0.669 0.331 0.000
Y57.9 Drug or medicament, unspecified
0.669 0.331 0.000
E13 Other specified diabetes mellitus
0.669 0.331 0.000
F31.8 Other bipolar affective disorders
0.668 0.332 0.000
F31.7 Bipolar affective disorder, currently in remission
0.668 0.332 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.668 0.332 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.668 0.332 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.668 0.332 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.668 0.332 0.000
R23.2 Flushing
0.667 0.333 0.000
T88.9 Complication of surgical and medical care, unspecified
0.666 0.334 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.666 0.334 0.000
T88.5 Other complications of anaesthesia
0.666 0.334 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.666 0.334 0.000
T88.2 Shock due to anaesthesia
0.666 0.334 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.666 0.334 0.000
T88.0 Infection following immunisation
0.666 0.334 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.666 0.334 0.000
M85 Other disorders of bone density and structure
0.666 0.334 0.000
E28 Ovarian dysfunction
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.666 0.334 0.000
S80.9 Superficial injury of lower leg, unspecified
0.665 0.335 0.000
E78.0 Pure hypercholesterolaemia
0.665 0.335 0.000
Q05 Spina bifida
0.664 0.336 0.000
E11.2 With renal complications
0.664 0.336 0.000
H33.4 Traction detachment of retina
0.663 0.336 0.000
H33.1 Retinoschisis and retinal cysts
0.663 0.336 0.000
S88 Traumatic amputation of lower leg
0.663 0.336 0.000
S87 Crushing injury of lower leg
0.663 0.336 0.000
S85 Injury of blood vessels at lower leg level
0.663 0.336 0.000
S84 Injury of nerves at lower leg level
0.663 0.336 0.000
M51 Other intervertebral disk disorders
0.662 0.338 0.000
E88 Other metabolic disorders
0.662 0.338 0.000
R76 Other abnormal immunological findings in serum
0.662 0.338 0.000
H35.8 Other specified retinal disorders
0.662 0.338 0.000
R00 Abnormalities of heart beat
0.661 0.339 0.000
E29 Testicular dysfunction
0.661 0.339 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.659 0.340 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.659 0.341 0.000
R07.0 Pain in throat
0.658 0.341 0.000
M06.8 Other specified rheumatoid arthritis
0.658 0.342 0.000
M06.4 Inflammatory polyarthropathy
0.658 0.342 0.000
M06.3 Rheumatoid nodule
0.658 0.342 0.000
M06.2 Rheumatoid bursitis
0.658 0.342 0.000
M06.1 Adult-onset Still's disease
0.658 0.342 0.000
M22.2 Patellofemoral disorders
0.657 0.343 0.000
M67 Other disorders of synovium and tendon
0.657 0.343 0.000
S40 Superficial injury of shoulder and upper arm
0.657 0.343 0.000
R52.1 Chronic intractable pain
0.656 0.344 0.000
H31.0 Chorioretinal scars
0.656 0.344 0.000
F40 Phobic anxiety disorders
0.656 0.344 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.655 0.345 0.000
R39.2 Extrarenal uraemia
0.655 0.345 0.000
R39.0 Extravasation of urine
0.655 0.345 0.000
Q61 Cystic kidney disease
0.655 0.345 0.000
R46.4 Slowness and poor responsiveness
0.655 0.345 0.000
E11.3 With ophthalmic complications
0.655 0.345 0.000
H16 Keratitis
0.654 0.346 0.000
R45.2 Unhappiness
0.654 0.346 0.000
S05.1 Contusion of eyeball and orbital tissues
0.653 0.347 0.000
R47.0 Dysphasia and aphasia
0.652 0.348 0.000
E27 Other disorders of adrenal gland
0.652 0.348 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.652 0.348 0.000
F42 Obsessive-compulsive disorder
0.652 0.348 0.000
R25.3 Fasciculation
0.651 0.349 0.000
R25.0 Abnormal head movements
0.651 0.349 0.000
M22.3 Other derangements of patella
0.651 0.349 0.000
S09.8 Other specified injuries of head
0.651 0.349 0.000
T63 Toxic effect of contact with venomous animals
0.651 0.349 0.000
G93.2 Benign intracranial hypertension
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.