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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76092860
log Bayes Factor = 17.1237
Chromosome 4   position 123,846,569  (GRCh37) Explore rs76092860 on Ensembl!
Variant rs76092860 is part of Cluster X0256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.998 0.002 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.998 0.002 0.000
M79.6 Pain in limb
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
M79.66 Pain in limb (Lower leg)
0.985 0.015 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.983 0.017 0.000
Chapter X Diseases of the respiratory system
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.977 0.023 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
M50-M54 Other dorsopathies
0.966 0.034 0.000
S00-S09 Injuries to the head
0.958 0.042 0.000
Chapter II Neoplasms
0.957 0.043 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.957 0.043 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.956 0.044 0.000
M79.8 Other specified soft tissue disorders
0.955 0.045 0.000
B95-B98 Bacterial, viral and other infectious agents
0.949 0.051 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.944 0.056 0.000
M54 Dorsalgia
0.941 0.059 0.000
E00-E07 Disorders of thyroid gland
0.936 0.064 0.000
B35-B49 Mycoses
0.932 0.068 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.926 0.074 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.926 0.074 0.000
Z03.4 Observation for suspected myocardial infarction
0.919 0.081 0.000
W00-W19 Falls
0.916 0.084 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.915 0.085 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.913 0.087 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.910 0.090 0.000
S01 Open wound of head
0.909 0.091 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.909 0.091 0.000
Z04 Examination and observation for other reasons
0.907 0.093 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.906 0.094 0.000
J20-J22 Other acute lower respiratory infections
0.906 0.094 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.906 0.094 0.000
F10.1 Harmful use
0.905 0.095 0.000
G90-G99 Other disorders of the nervous system
0.904 0.096 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.904 0.096 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.903 0.097 0.000
M54.5 Low back pain
0.896 0.104 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.895 0.105 0.000
H30-H36 Disorders of choroid and retina
0.894 0.106 0.000
H53-H54 Visual disturbances and blindness
0.894 0.106 0.000
B37 Candidiasis
0.892 0.108 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.885 0.115 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.881 0.119 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.880 0.120 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.877 0.123 0.000
C15-C26 Malignant neoplasms of digestive organs
0.875 0.125 0.000
J00-J06 Acute upper respiratory infections
0.875 0.125 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.874 0.126 0.000
Chapter IX Diseases of the circulatory system
0.870 0.130 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.870 0.130 0.000
E20-E35 Disorders of other endocrine glands
0.869 0.131 0.000
M45-M49 Spondylopathies
0.867 0.133 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.866 0.134 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.863 0.137 0.000
Z13 Special screening examination for other diseases and disorders
0.863 0.137 0.000
W19 Unspecified fall
0.863 0.137 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.860 0.140 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.858 0.142 0.000
H35 Other retinal disorders
0.858 0.142 0.000
J22 Unspecified acute lower respiratory infection
0.853 0.147 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.852 0.148 0.000
Z02 Examination and encounter for administrative purposes
0.852 0.148 0.000
F10.0 Acute intoxication
0.852 0.148 0.000
Chapter VIII Diseases of the ear and mastoid process
0.846 0.154 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.843 0.157 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.842 0.158 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.841 0.159 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.839 0.161 0.000
M72 Fibroblastic disorders
0.838 0.162 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.833 0.167 0.000
W19.9 Unspecified place
0.832 0.168 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.830 0.170 0.000
J60-J70 Lung diseases due to external agents
0.829 0.170 0.000
H35.3 Degeneration of macula and posterior pole
0.829 0.171 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.828 0.172 0.000
I77 Other disorders of arteries and arterioles
0.827 0.173 0.000
G81 Hemiplegia
0.826 0.174 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.823 0.177 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.822 0.178 0.000
C18 Malignant neoplasm of colon
0.821 0.179 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.819 0.181 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.819 0.181 0.000
G50 Disorders of trigeminal nerve
0.818 0.182 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.818 0.182 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.815 0.184 0.000
M54.56 Low back pain (Lumbar region)
0.814 0.186 0.000
M54.57 Low back pain (Lumbosacral region)
0.809 0.191 0.000
L60-L75 Disorders of skin appendages
0.808 0.192 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.808 0.192 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.805 0.195 0.000
S09 Other and unspecified injuries of head
0.804 0.196 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.804 0.196 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.804 0.196 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.804 0.196 0.000
M79.62 Pain in limb (Upper arm)
0.803 0.196 0.000
Chapter XXII Codes for special purposes
0.802 0.198 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.801 0.198 0.000
I77.1 Stricture of artery
0.801 0.199 0.000
J95-J99 Other diseases of the respiratory system
0.801 0.199 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.800 0.200 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.800 0.200 0.000
T81 Complications of procedures, not elsewhere classified
0.799 0.201 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.799 0.201 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.799 0.201 0.000
E05.9 Thyrotoxicosis, unspecified
0.798 0.202 0.000
M79.67 Pain in limb (Ankle and foot)
0.798 0.202 0.000
Z04.8 Examination and observation for other specified reasons
0.797 0.203 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.796 0.204 0.000
J02 Acute pharyngitis
0.796 0.204 0.000
B37.8 Candidiasis of other sites
0.794 0.206 0.000
H53 Visual disturbances
0.793 0.207 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.790 0.210 0.000
I73 Other peripheral vascular diseases
0.789 0.211 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.788 0.212 0.000
A80-A89 Viral infections of the central nervous system
0.787 0.213 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.784 0.216 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.784 0.216 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.783 0.217 0.000
I74 Arterial embolism and thrombosis
0.782 0.218 0.000
M54.4 Lumbago with sciatica
0.781 0.219 0.000
G50.0 Trigeminal neuralgia
0.781 0.219 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.780 0.220 0.000
F30-F39 Mood [affective] disorders
0.779 0.221 0.000
G40-G47 Episodic and paroxysmal disorders
0.778 0.222 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.777 0.223 0.000
T39.1 4-Aminophenol derivatives
0.776 0.224 0.000
E03 Other hypothyroidism
0.776 0.224 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.775 0.225 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.775 0.225 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.774 0.226 0.000
Z22 Carrier of infectious disease
0.774 0.226 0.000
Y43 Primarily systemic agents
0.773 0.227 0.000
H10-H13 Disorders of conjunctiva
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.772 0.228 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.771 0.229 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.770 0.230 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.770 0.230 0.000
Z01.6 Radiological examination, not elsewhere classified
0.767 0.233 0.000
S01.8 Open wound of other parts of head
0.767 0.233 0.000
X60-X84 Intentional self-harm
0.766 0.234 0.000
G93 Other disorders of brain
0.766 0.234 0.000
G81.9 Hemiplegia, unspecified
0.766 0.234 0.000
E04 Other non-toxic goitre
0.765 0.235 0.000
M71 Other bursopathies
0.763 0.237 0.000
B37.9 Candidiasis, unspecified
0.762 0.238 0.000
A30-A49 Other bacterial diseases
0.762 0.238 0.000
S60-S69 Injuries to the wrist and hand
0.761 0.239 0.000
C64-C68 Malignant neoplasms of urinary tract
0.761 0.239 0.000
M77 Other enthesopathies
0.758 0.242 0.000
T82.1 Mechanical complication of cardiac electronic device
0.758 0.242 0.000
M86-M90 Other osteopathies
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.757 0.243 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
H25-H28 Disorders of lens
0.756 0.244 0.000
Z04.3 Examination and observation following other accident
0.755 0.245 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.754 0.246 0.000
S01.0 Open wound of scalp
0.754 0.246 0.000
S01.5 Open wound of lip and oral cavity
0.754 0.246 0.000
G91 Hydrocephalus
0.753 0.247 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.753 0.247 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.751 0.249 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.750 0.250 0.000
H55-H59 Other disorders of eye and adnexa
0.750 0.250 0.000
T66-T78 Other and unspecified effects of external causes
0.749 0.251 0.000
Z02.8 Other examinations for administrative purposes
0.748 0.252 0.000
M79.64 Pain in limb (Hand)
0.747 0.253 0.000
L03 Cellulitis
0.747 0.253 0.000
C92 Myeloid leukaemia
0.747 0.253 0.000
T79-T79 Certain early complications of trauma
0.746 0.254 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
B37.0 Candidal stomatitis
0.745 0.255 0.000
I73.9 Peripheral vascular disease, unspecified
0.745 0.255 0.000
F80-F89 Disorders of psychological development
0.745 0.255 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.745 0.255 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.743 0.256 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.743 0.256 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.743 0.257 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.741 0.259 0.000
C91 Lymphoid leukaemia
0.740 0.260 0.000
J02.9 Acute pharyngitis, unspecified
0.739 0.261 0.000
M79.69 Pain in limb (Site unspecified)
0.739 0.261 0.000
M54.3 Sciatica
0.737 0.262 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.737 0.263 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
M51 Other intervertebral disk disorders
0.735 0.265 0.000
Z60 Problems related to social environment
0.733 0.267 0.000
M53 Other dorsopathies, not elsewhere classified
0.733 0.267 0.000
M79.60 Pain in limb (Multiple sites)
0.732 0.268 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.732 0.268 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.729 0.271 0.000
F10.3 Withdrawal state
0.727 0.272 0.000
G83 Other paralytic syndromes
0.727 0.273 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.726 0.273 0.000
E10-E14 Diabetes mellitus
0.726 0.274 0.000
E70-E90 Metabolic disorders
0.726 0.274 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.724 0.276 0.000
S01.2 Open wound of nose
0.723 0.277 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.722 0.278 0.000
E23 Hypofunction and other disorders of pituitary gland
0.722 0.278 0.000
H43-H45 Disorders of vitreous body and globe
0.722 0.278 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.721 0.279 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.720 0.280 0.000
H50 Other strabismus
0.720 0.280 0.000
H35.6 Retinal haemorrhage
0.718 0.282 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.715 0.284 0.000
M79.9 Soft tissue disorder, unspecified
0.715 0.284 0.000
M79.7 Fibromyalgia
0.715 0.284 0.000
M79.5 Residual foreign body in soft tissue
0.715 0.284 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.715 0.284 0.000
M79.3 Panniculitis, unspecified
0.715 0.284 0.000
M79.2 Neuralgia and neuritis, unspecified
0.715 0.284 0.000
M79.1 Myalgia
0.715 0.284 0.000
H54 Blindness and low vision
0.715 0.285 0.000
M79.68 Pain in limb (Other)
0.714 0.286 0.000
M79.63 Pain in limb (Forearm)
0.714 0.286 0.000
M79.61 Pain in limb (Shoulder region)
0.714 0.286 0.000
B25-B34 Other viral diseases
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
F10.2 Dependence syndrome
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
C81 Hodgkin's disease
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
S01.1 Open wound of eyelid and periocular area
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.709 0.291 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B65-B83 Helminthiases
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.709 0.291 0.000
B15-B19 Viral hepatitis
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
C18.2 Ascending colon
0.709 0.291 0.000
F41 Other anxiety disorders
0.708 0.292 0.000
J81 Pulmonary oedema
0.708 0.292 0.000
H90-H95 Other disorders of ear
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.706 0.294 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.706 0.294 0.000
F99-F99 Unspecified mental disorder
0.705 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.294 0.000
F70-F79 Mental retardation
0.705 0.294 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.294 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.705 0.295 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.705 0.295 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.705 0.295 0.000
T82.3 Mechanical complication of other vascular grafts
0.705 0.295 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.705 0.295 0.000
C51-C58 Malignant neoplasms of female genital organs
0.704 0.295 0.000
C18.9 Colon, unspecified
0.702 0.298 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.701 0.298 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.701 0.299 0.000
G95 Other diseases of spinal cord
0.700 0.300 0.000
E40-E46 Malnutrition
0.700 0.300 0.000
S00 Superficial injury of head
0.700 0.300 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.699 0.301 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.699 0.301 0.000
J69 Pneumonitis due to solids and liquids
0.699 0.301 0.000
M54.9 Dorsalgia, unspecified
0.698 0.302 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.698 0.302 0.000
Z22.3 Carrier of other specified bacterial diseases
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.697 0.303 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.697 0.303 0.000
L08 Other local infections of skin and subcutaneous tissue
0.696 0.304 0.000
G35 Multiple sclerosis
0.696 0.304 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.695 0.305 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.695 0.305 0.000
T39.0 Salicylates
0.694 0.306 0.000
S09.9 Unspecified injury of head
0.694 0.306 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.693 0.307 0.000
G62 Other polyneuropathies
0.692 0.308 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.688 0.312 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.688 0.312 0.000
S08 Traumatic amputation of part of head
0.687 0.313 0.000
S07 Crushing injury of head
0.687 0.313 0.000
S05 Injury of eye and orbit
0.687 0.313 0.000
S04 Injury of cranial nerves
0.687 0.313 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.687 0.313 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.686 0.314 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.686 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.686 0.314 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.686 0.314 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.686 0.314 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.686 0.314 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.686 0.314 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.686 0.314 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.686 0.314 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.686 0.314 0.000
F11 Mental and behavioural disorders due to use of opioids
0.686 0.314 0.000
J90-J94 Other diseases of pleura
0.686 0.314 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.685 0.315 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.685 0.315 0.000
Z03.0 Observation for suspected tuberculosis
0.685 0.315 0.000
M79.88 Other specified soft tissue disorders (Other)
0.685 0.315 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.685 0.315 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.685 0.315 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.685 0.315 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.685 0.315 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.685 0.315 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.685 0.315 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.684 0.316 0.000
T85.2 Mechanical complication of intraocular lens
0.684 0.316 0.000
M48 Other spondylopathies
0.684 0.316 0.000
Z29 Need for other prophylactic measures
0.683 0.317 0.000
T18 Foreign body in alimentary tract
0.683 0.317 0.000
S80-S89 Injuries to the knee and lower leg
0.683 0.317 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.683 0.317 0.000
J98 Other respiratory disorders
0.682 0.318 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.681 0.319 0.000
H80-H83 Diseases of inner ear
0.681 0.319 0.000
G20-G26 Extrapyramidal and movement disorders
0.680 0.319 0.000
L50-L54 Urticaria and erythema
0.680 0.320 0.000
M54.1 Radiculopathy
0.679 0.320 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.679 0.321 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.679 0.321 0.000
L72.1 Trichilemmal cyst
0.677 0.323 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.677 0.323 0.000
M45 Ankylosing spondylitis
0.677 0.323 0.000
I60-I69 Cerebrovascular diseases
0.677 0.323 0.000
F10.9 Unspecified mental and behavioural disorder
0.677 0.323 0.000
F10.8 Other mental and behavioural disorders
0.677 0.323 0.000
F10.7 Residual and late-onset psychotic disorder
0.677 0.323 0.000
F10.6 Amnesic syndrome
0.677 0.323 0.000
F10.5 Psychotic disorder
0.677 0.323 0.000
F10.4 Withdrawal state with delirium
0.677 0.323 0.000
M47 Spondylosis
0.677 0.323 0.000
H53.9 Visual disturbance, unspecified
0.676 0.324 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.676 0.324 0.000
S06 Intracranial injury
0.676 0.324 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.676 0.324 0.000
E07 Other disorders of thyroid
0.675 0.324 0.000
H36 Retinal disorders in diseases classified elsewhere
0.675 0.325 0.000
H25 Senile cataract
0.675 0.325 0.000
M54.8 Other dorsalgia
0.674 0.325 0.000
M54.6 Pain in thoracic spine
0.674 0.325 0.000
M54.0 Panniculitis affecting regions of neck and back
0.674 0.325 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.674 0.326 0.000
M54.2 Cervicalgia
0.674 0.326 0.000
S20-S29 Injuries to the thorax
0.674 0.326 0.000
Y42.7 Androgens and anabolic congeners
0.672 0.328 0.000
E16 Other disorders of pancreatic internal secretion
0.672 0.328 0.000
E06 Thyroiditis
0.671 0.329 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.671 0.329 0.000
E00 Congenital iodine-deficiency syndrome
0.671 0.329 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.671 0.329 0.000
J04 Acute laryngitis and tracheitis
0.671 0.329 0.000
C67 Malignant neoplasm of bladder
0.671 0.329 0.000
H52 Disorders of refraction and accommodation
0.669 0.331 0.000
B48 Other mycoses, not elsewhere classified
0.668 0.331 0.000
B47 Mycetoma
0.668 0.331 0.000
B46 Zygomycosis
0.668 0.331 0.000
B45 Cryptococcosis
0.668 0.331 0.000
B44 Aspergillosis
0.668 0.331 0.000
B43 Chromomycosis and phaeomycotic abscess
0.668 0.331 0.000
B42 Sporotrichosis
0.668 0.331 0.000
B41 Paracoccidioidomycosis
0.668 0.331 0.000
B40 Blastomycosis
0.668 0.331 0.000
B39 Histoplasmosis
0.668 0.331 0.000
B38 Coccidioidomycosis
0.668 0.331 0.000
B36 Other superficial mycoses
0.668 0.331 0.000
B35 Dermatophytosis
0.668 0.331 0.000
B49 Unspecified mycosis
0.668 0.331 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.667 0.333 0.000
Y44 Agents primarily affecting blood constituents
0.667 0.333 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.667 0.333 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.666 0.333 0.000
S02 Fracture of skull and facial bones
0.666 0.334 0.000
E50-E64 Other nutritional deficiencies
0.665 0.335 0.000
T51 Toxic effect of alcohol
0.665 0.335 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.664 0.336 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.664 0.336 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.664 0.336 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.664 0.336 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.664 0.336 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.663 0.337 0.000
Z30 Contraceptive management
0.663 0.337 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.663 0.337 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.662 0.338 0.000
F41.2 Mixed anxiety and depressive disorder
0.662 0.338 0.000
Z01.8 Other specified special examinations
0.662 0.338 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.661 0.338 0.000
J80 Adult respiratory distress syndrome
0.661 0.338 0.000
H53.4 Visual field defects
0.661 0.339 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.661 0.339 0.000
E03.9 Hypothyroidism, unspecified
0.661 0.339 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.660 0.339 0.000
I72 Other aneurysm
0.660 0.340 0.000
L03.1 Cellulitis of other parts of limb
0.659 0.341 0.000
Y83.9 Surgical procedure, unspecified
0.659 0.341 0.000
C73 Malignant neoplasm of thyroid gland
0.658 0.342 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.658 0.342 0.000
M46 Other inflammatory spondylopathies
0.658 0.342 0.000
E27 Other disorders of adrenal gland
0.657 0.343 0.000
W18 Other fall on same level
0.657 0.343 0.000
W17 Other fall from one level to another
0.657 0.343 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.657 0.343 0.000
W15 Fall from cliff
0.657 0.343 0.000
W14 Fall from tree
0.657 0.343 0.000
W13 Fall from, out of or through building or structure
0.657 0.343 0.000
W12 Fall on and from scaffolding
0.657 0.343 0.000
W11 Fall on and from ladder
0.657 0.343 0.000
W10 Fall on and from stairs and steps
0.657 0.343 0.000
W09 Fall involving playground equipment
0.657 0.343 0.000
W08 Fall involving other furniture
0.657 0.343 0.000
W07 Fall involving chair
0.657 0.343 0.000
W06 Fall involving bed
0.657 0.343 0.000
W05 Fall involving wheelchair
0.657 0.343 0.000
W04 Fall while being carried or supported by other persons
0.657 0.343 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.657 0.343 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.657 0.343 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.657 0.343 0.000
W00 Fall on same level involving ice and snow
0.657 0.343 0.000
L10-L14 Bullous disorders
0.656 0.344 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.656 0.344 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.655 0.345 0.000
C95 Leukaemia of unspecified cell type
0.655 0.345 0.000
C94 Other leukaemias of specified cell type
0.655 0.345 0.000
C93 Monocytic leukaemia
0.655 0.345 0.000
C88 Malignant immunoproliferative diseases
0.655 0.345 0.000
C86 Other specified types of T/NK-cell lymphoma
0.655 0.345 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.655 0.345 0.000
G93.4 Encephalopathy, unspecified
0.655 0.345 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.654 0.346 0.000
H40-H42 Glaucoma
0.654 0.346 0.000
Z60.2 Living alone
0.654 0.346 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.653 0.347 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.653 0.347 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.653 0.347 0.000
G82 Paraplegia and tetraplegia
0.652 0.347 0.000
G80 Infantile cerebral palsy
0.652 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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