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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76176567
log Bayes Factor = 14.1328
Chromosome 14   position 52,870,219  (GRCh37) Explore rs76176567 on Ensembl!
Variant rs76176567 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
N40-N51 Diseases of male genital organs
0.994 0.006 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
N40 Hyperplasia of prostate
0.992 0.008 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
I60-I69 Cerebrovascular diseases
0.986 0.014 0.000
M06.9 Rheumatoid arthritis, unspecified
0.983 0.017 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.979 0.021 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.975 0.025 0.000
M50-M54 Other dorsopathies
0.973 0.027 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.971 0.029 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.967 0.033 0.000
I10-I15 Hypertensive diseases
0.963 0.037 0.000
F10.0 Acute intoxication
0.963 0.037 0.000
D60-D64 Aplastic and other anaemias
0.959 0.041 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.958 0.042 0.000
I45 Other conduction disorders
0.954 0.046 0.000
Chapter II Neoplasms
0.951 0.049 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.948 0.052 0.000
I12 Hypertensive renal disease
0.946 0.054 0.000
I34 Nonrheumatic mitral valve disorders
0.946 0.054 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.940 0.060 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.937 0.063 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.934 0.066 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.930 0.070 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.921 0.079 0.000
D64 Other anaemias
0.917 0.083 0.000
M54 Dorsalgia
0.913 0.087 0.000
C44 Other malignant neoplasms of skin
0.911 0.089 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.909 0.091 0.000
I69 Sequelae of cerebrovascular disease
0.909 0.091 0.000
I34.1 Mitral (valve) prolapse
0.907 0.093 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.907 0.093 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.906 0.094 0.000
M50 Cervical disk disorders
0.905 0.095 0.000
F10.3 Withdrawal state
0.904 0.096 0.000
M54.2 Cervicalgia
0.902 0.098 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.900 0.100 0.000
E70-E90 Metabolic disorders
0.896 0.104 0.000
M54.22 Cervicalgia (Cervical region)
0.895 0.105 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.894 0.106 0.000
C44.7 Skin of lower limb, including hip
0.892 0.108 0.000
I51 Complications and ill-defined descriptions of heart disease
0.892 0.108 0.000
Chapter XX External causes of morbidity and mortality
0.888 0.112 0.000
I12.0 Hypertensive renal disease with renal failure
0.888 0.112 0.000
I12.9 Hypertensive renal disease without renal failure
0.888 0.112 0.000
N25-N29 Other disorders of kidney and ureter
0.886 0.114 0.000
D64.9 Anaemia, unspecified
0.886 0.114 0.000
G30-G32 Other degenerative diseases of the nervous system
0.883 0.117 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.881 0.119 0.000
G90-G99 Other disorders of the nervous system
0.876 0.124 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.876 0.124 0.000
A00-A09 Intestinal infectious diseases
0.875 0.125 0.000
I67 Other cerebrovascular diseases
0.874 0.126 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.872 0.128 0.000
C43 Malignant melanoma of skin
0.867 0.133 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.867 0.133 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.866 0.134 0.000
N17-N19 Renal failure
0.865 0.135 0.000
S80-S89 Injuries to the knee and lower leg
0.860 0.140 0.000
M10 Gout
0.859 0.141 0.000
I45.1 Other and unspecified right bundle-branch block
0.859 0.141 0.000
N42 Other disorders of prostate
0.857 0.143 0.000
S90-S99 Injuries to the ankle and foot
0.854 0.146 0.000
C44.1 Skin of eyelid, including canthus
0.853 0.147 0.000
D72 Other disorders of white blood cells
0.850 0.150 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.849 0.151 0.000
I15 Secondary hypertension
0.849 0.151 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.848 0.152 0.000
S40-S49 Injuries to the shoulder and upper arm
0.848 0.152 0.000
C64-C68 Malignant neoplasms of urinary tract
0.846 0.154 0.000
S70-S79 Injuries to the hip and thigh
0.846 0.154 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.844 0.156 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.843 0.157 0.000
I46 Cardiac arrest
0.839 0.161 0.000
I61 Intracerebral haemorrhage
0.839 0.161 0.000
D50-D53 Nutritional anaemias
0.839 0.161 0.000
T79-T79 Certain early complications of trauma
0.838 0.162 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.837 0.163 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.837 0.163 0.000
M06.0 Seronegative rheumatoid arthritis
0.837 0.163 0.000
T66-T78 Other and unspecified effects of external causes
0.835 0.165 0.000
M05 Seropositive rheumatoid arthritis
0.833 0.167 0.000
T86 Failure and rejection of transplanted organs and tissues
0.833 0.167 0.000
N99-N99 Other disorders of the genitourinary system
0.828 0.172 0.000
A30-A49 Other bacterial diseases
0.828 0.172 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.827 0.173 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.827 0.173 0.000
T39.1 4-Aminophenol derivatives
0.826 0.174 0.000
F99-F99 Unspecified mental disorder
0.825 0.175 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.824 0.176 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.823 0.177 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.821 0.179 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.818 0.182 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.815 0.185 0.000
E87.5 Hyperkalaemia
0.810 0.190 0.000
I45.9 Conduction disorder, unspecified
0.810 0.190 0.000
F05.9 Delirium, unspecified
0.809 0.191 0.000
D68 Other coagulation defects
0.808 0.192 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.807 0.193 0.000
C51-C58 Malignant neoplasms of female genital organs
0.805 0.195 0.000
I60 Subarachnoid haemorrhage
0.803 0.197 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.802 0.198 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.800 0.200 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.800 0.200 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.799 0.201 0.000
T18 Foreign body in alimentary tract
0.798 0.202 0.000
B35-B49 Mycoses
0.798 0.202 0.000
M86-M90 Other osteopathies
0.797 0.202 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.796 0.204 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.796 0.204 0.000
M54.1 Radiculopathy
0.796 0.204 0.000
F03 Unspecified dementia
0.795 0.205 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.792 0.208 0.000
Chapter VII Diseases of the eye and adnexa
0.792 0.208 0.000
M70-M79 Other soft tissue disorders
0.789 0.211 0.000
M50.1 Cervical disk disorder with radiculopathy
0.789 0.211 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.788 0.212 0.000
M11 Other crystal arthropathies
0.787 0.213 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.787 0.213 0.000
I67.8 Other specified cerebrovascular diseases
0.786 0.214 0.000
N17 Acute renal failure
0.784 0.216 0.000
D45 Polycythaemia vera
0.784 0.216 0.000
I38 Endocarditis, valve unspecified
0.782 0.218 0.000
D62 Acute posthaemorrhagic anaemia
0.781 0.219 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.781 0.219 0.000
B25-B34 Other viral diseases
0.780 0.220 0.000
I65.2 Occlusion and stenosis of carotid artery
0.780 0.220 0.000
S20-S29 Injuries to the thorax
0.779 0.221 0.000
I37 Pulmonary valve disorders
0.778 0.222 0.000
E87.2 Acidosis
0.776 0.224 0.000
D46 Myelodysplastic syndromes
0.776 0.224 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.775 0.225 0.000
D75 Other diseases of blood and blood-forming organs
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
B99-B99 Other infectious diseases
0.773 0.226 0.000
B15-B19 Viral hepatitis
0.772 0.228 0.000
N50 Other disorders of male genital organs
0.770 0.230 0.000
E50-E64 Other nutritional deficiencies
0.770 0.230 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.767 0.233 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.766 0.234 0.000
D72.8 Other specified disorders of white blood cells
0.766 0.234 0.000
E10-E14 Diabetes mellitus
0.765 0.235 0.000
M40-M43 Deforming dorsopathies
0.765 0.235 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.764 0.236 0.000
I42 Cardiomyopathy
0.762 0.238 0.000
M10.9 Gout, unspecified
0.761 0.239 0.000
C44.5 Skin of trunk
0.761 0.239 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.760 0.240 0.000
I45.3 Trifascicular block
0.760 0.240 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.241 0.000
I51.6 Cardiovascular disease, unspecified
0.757 0.243 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.757 0.243 0.000
D80-D89 Certain disorders involving the immune mechanism
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
E83 Disorders of mineral metabolism
0.751 0.249 0.000
M06.3 Rheumatoid nodule
0.751 0.249 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.751 0.249 0.000
D69 Purpura and other haemorrhagic conditions
0.749 0.251 0.000
T17 Foreign body in respiratory tract
0.749 0.251 0.000
F00 Dementia in Alzheimer's disease
0.748 0.252 0.000
Y84.0 Cardiac catheterisation
0.747 0.253 0.000
S92 Fracture of foot, except ankle
0.746 0.254 0.000
I45.2 Bifascicular block
0.746 0.254 0.000
T42.4 Benzodiazepines
0.745 0.255 0.000
I46.9 Cardiac arrest, unspecified
0.743 0.257 0.000
B02 Zoster [herpes zoster]
0.742 0.258 0.000
M50.9 Cervical disk disorder, unspecified
0.742 0.258 0.000
T31 Burns classified according to extent of body surface involved
0.741 0.259 0.000
M50.3 Other cervical disk degeneration
0.741 0.259 0.000
N48 Other disorders of penis
0.740 0.260 0.000
W20-W49 Exposure to inanimate mechanical forces
0.737 0.263 0.000
N42.8 Other specified disorders of prostate
0.737 0.263 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.737 0.263 0.000
D72.1 Eosinophilia
0.735 0.265 0.000
F10.2 Dependence syndrome
0.734 0.266 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.733 0.267 0.000
G70-G73 Diseases of myoneural junction and muscle
0.733 0.267 0.000
I51.7 Cardiomegaly
0.733 0.267 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.732 0.268 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.731 0.269 0.000
I35 Nonrheumatic aortic valve disorders
0.729 0.271 0.000
B65-B83 Helminthiases
0.729 0.271 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.271 0.000
I44 Atrioventricular and left bundle-branch block
0.728 0.272 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.728 0.272 0.000
N45 Orchitis and epididymitis
0.728 0.272 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.727 0.273 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.727 0.273 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.726 0.273 0.000
N17.9 Acute renal failure, unspecified
0.726 0.274 0.000
M53 Other dorsopathies, not elsewhere classified
0.726 0.274 0.000
S00-S09 Injuries to the head
0.726 0.274 0.000
S81 Open wound of lower leg
0.724 0.276 0.000
N43 Hydrocele and spermatocele
0.724 0.276 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.722 0.277 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.722 0.278 0.000
N42.1 Congestion and haemorrhage of prostate
0.722 0.278 0.000
T18.1 Foreign body in oesophagus
0.720 0.279 0.000
I15.9 Seconday hypertension, unspecified
0.720 0.280 0.000
D55-D59 Haemolytic anaemias
0.719 0.281 0.000
D50 Iron deficiency anaemia
0.719 0.281 0.000
Y84.2 Radiological procedure and radiotherapy
0.718 0.282 0.000
E87.0 Hyperosmolality and hypernatraemia
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.716 0.284 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.716 0.284 0.000
M65-M68 Disorders of synovium and tendon
0.715 0.285 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
N26 Unspecified contracted kidney
0.714 0.286 0.000
G82 Paraplegia and tetraplegia
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
I49 Other cardiac arrhythmias
0.713 0.287 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.713 0.287 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.713 0.287 0.000
N46 Male infertility
0.713 0.287 0.000
N44 Torsion of testis
0.713 0.287 0.000
I67.2 Cerebral atherosclerosis
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.711 0.289 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
M06.8 Other specified rheumatoid arthritis
0.710 0.289 0.000
M06.4 Inflammatory polyarthropathy
0.710 0.289 0.000
M06.2 Rheumatoid bursitis
0.710 0.289 0.000
M06.1 Adult-onset Still's disease
0.710 0.289 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A80-A89 Viral infections of the central nervous system
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
T86.0 Bone-marrow transplant rejection
0.707 0.293 0.000
M15-M19 Arthrosis
0.707 0.293 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.707 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
F80-F89 Disorders of psychological development
0.706 0.293 0.000
I05-I09 Chronic rheumatic heart diseases
0.706 0.294 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.706 0.294 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.705 0.295 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.705 0.295 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.705 0.295 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.705 0.295 0.000
F99 Mental disorder, not otherwise specified
0.704 0.296 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.704 0.296 0.000
D50.8 Other iron deficiency anaemias
0.704 0.296 0.000
C43.5 Malignant melanoma of trunk
0.703 0.297 0.000
C44.3 Skin of other and unspecified parts of face
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.298 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.298 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.298 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.298 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.298 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.298 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.702 0.298 0.000
F11 Mental and behavioural disorders due to use of opioids
0.702 0.298 0.000
G95 Other diseases of spinal cord
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
M50.0 Cervical disk disorder with myelopathy
0.701 0.299 0.000
M54.6 Pain in thoracic spine
0.699 0.301 0.000
F10.9 Unspecified mental and behavioural disorder
0.699 0.301 0.000
F10.8 Other mental and behavioural disorders
0.699 0.301 0.000
F10.7 Residual and late-onset psychotic disorder
0.699 0.301 0.000
F10.6 Amnesic syndrome
0.699 0.301 0.000
F10.5 Psychotic disorder
0.699 0.301 0.000
F10.4 Withdrawal state with delirium
0.699 0.301 0.000
G30 Alzheimer's disease
0.698 0.302 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.697 0.303 0.000
F60-F69 Disorders of adult personality and behaviour
0.697 0.303 0.000
I15.1 Hypertension secondary to other renal disorders
0.697 0.303 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.696 0.304 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.696 0.304 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.696 0.304 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.696 0.304 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.696 0.304 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
T36 Poisoning by systemic antibiotics
0.696 0.304 0.000
Q80-Q89 Other congenital malformations
0.696 0.304 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.695 0.304 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.695 0.305 0.000
C43.4 Malignant melanoma of scalp and neck
0.695 0.305 0.000
G91 Hydrocephalus
0.694 0.306 0.000
Chapter VIII Diseases of the ear and mastoid process
0.694 0.306 0.000
T87 Complications peculiar to reattachment and amputation
0.693 0.306 0.000
M20-M25 Other joint disorders
0.693 0.307 0.000
I62 Other nontraumatic intracranial haemorrhage
0.693 0.307 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.691 0.309 0.000
I13 Hypertensive heart and renal disease
0.691 0.309 0.000
I11 Hypertensive heart disease
0.691 0.309 0.000
G96 Other disorders of central nervous system
0.691 0.309 0.000
Y84.1 Kidney dialysis
0.690 0.309 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.690 0.310 0.000
H40-H42 Glaucoma
0.689 0.311 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.688 0.312 0.000
I47 Paroxysmal tachycardia
0.688 0.312 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.686 0.314 0.000
D68.8 Other specified coagulation defects
0.686 0.314 0.000
M54.12 Radiculopathy (Cervical region)
0.684 0.316 0.000
I45.8 Other specified conduction disorders
0.684 0.316 0.000
I45.6 Preexcitation syndrome
0.684 0.316 0.000
I45.5 Other specified heart block
0.684 0.316 0.000
I45.4 Nonspecific intraventricular block
0.684 0.316 0.000
I45.0 Right fascicular block
0.684 0.316 0.000
E87.3 Alkalosis
0.683 0.317 0.000
D37.4 Colon
0.683 0.317 0.000
T51 Toxic effect of alcohol
0.682 0.318 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.682 0.318 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.682 0.318 0.000
N10-N16 Renal tubulo-interstitial diseases
0.682 0.318 0.000
T78 Adverse effects, not elsewhere classified
0.681 0.319 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.681 0.319 0.000
Y95 Nosocomial condition
0.680 0.320 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.679 0.320 0.000
F02 Dementia in other diseases classified elsewhere
0.679 0.320 0.000
F09 Unspecified organic or symptomatic mental disorder
0.679 0.320 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.679 0.320 0.000
E16 Other disorders of pancreatic internal secretion
0.679 0.321 0.000
M91-M94 Chondropathies
0.678 0.321 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.678 0.322 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.678 0.322 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.675 0.325 0.000
D37.7 Other digestive organs
0.675 0.325 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.673 0.327 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.672 0.327 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.672 0.327 0.000
F01 Vascular dementia
0.672 0.328 0.000
G80 Infantile cerebral palsy
0.672 0.328 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.672 0.328 0.000
E55 Vitamin D deficiency
0.670 0.330 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.670 0.330 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.670 0.330 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.670 0.330 0.000
T82.3 Mechanical complication of other vascular grafts
0.670 0.330 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.670 0.330 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.670 0.330 0.000
I51.8 Other ill-defined heart diseases
0.669 0.331 0.000
B25 Cytomegaloviral disease
0.668 0.332 0.000
E20-E35 Disorders of other endocrine glands
0.667 0.333 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.667 0.333 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.667 0.333 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.667 0.333 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.667 0.333 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.667 0.333 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.667 0.333 0.000
G81 Hemiplegia
0.666 0.334 0.000
D61 Other aplastic anaemias
0.666 0.334 0.000
E87.6 Hypokalaemia
0.666 0.334 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.665 0.335 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.664 0.335 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
E83.5 Disorders of calcium metabolism
0.664 0.336 0.000
T31.0 Burns involving less than 10% of body surface
0.664 0.336 0.000
Q60-Q64 Congenital malformations of the urinary system
0.664 0.336 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.663 0.337 0.000
T39.0 Salicylates
0.663 0.337 0.000
G93 Other disorders of brain
0.663 0.337 0.000
G31.8 Other specified degenerative diseases of nervous system
0.662 0.338 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.662 0.338 0.000
M80-M85 Disorders of bone density and structure
0.662 0.338 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.662 0.338 0.000
D37.2 Small intestine
0.662 0.338 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.661 0.338 0.000
I49.8 Other specified cardiac arrhythmias
0.661 0.339 0.000
E88 Other metabolic disorders
0.661 0.339 0.000
B37 Candidiasis
0.661 0.339 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.660 0.340 0.000
X20-X29 Contact with venomous animals and plants
0.660 0.340 0.000
S70 Superficial injury of hip and thigh
0.660 0.340 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.659 0.341 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.659 0.341 0.000
Q00-Q07 Congenital malformations of the nervous system
0.658 0.342 0.000
V20-V29 Motorcycle rider injured in transport accident
0.658 0.342 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.658 0.342 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.658 0.342 0.000
C65 Malignant neoplasm of renal pelvis
0.658 0.342 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.658 0.342 0.000
D64.8 Other specified anaemias
0.657 0.343 0.000
D64.4 Congenital dyserythropoietic anaemia
0.657 0.343 0.000
D64.3 Other sideroblastic anaemias
0.657 0.343 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.657 0.343 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.657 0.343 0.000
D64.0 Hereditary sideroblastic anaemia
0.657 0.343 0.000
S09 Other and unspecified injuries of head
0.657 0.343 0.000
Y84.6 Urinary catheterisation
0.657 0.343 0.000
T14 Injury of unspecified body region
0.656 0.344 0.000
N00-N08 Glomerular diseases
0.655 0.344 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.655 0.345 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.655 0.345 0.000
D47.1 Chronic myeloproliferative disease
0.655 0.345 0.000
M54.8 Other dorsalgia
0.655 0.345 0.000
M54.0 Panniculitis affecting regions of neck and back
0.655 0.345 0.000
T68 Hypothermia
0.654 0.346 0.000
I30 Acute pericarditis
0.653 0.347 0.000
H18 Other disorders of cornea
0.653 0.347 0.000
C44.8 Overlapping lesion of skin
0.653 0.347 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.653 0.347 0.000
D67 Hereditary factor IX deficiency
0.652 0.348 0.000
D66 Hereditary factor VIII deficiency
0.652 0.348 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.652 0.348 0.000
C51 Malignant neoplasm of vulva
0.652 0.348 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.652 0.348 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.652 0.348 0.000
A40 Streptococcal septicaemia
0.651 0.349 0.000
T19 Foreign body in genito-urinary tract
0.650 0.350 0.000
T15 Foreign body on external eye
0.650 0.350 0.000
T16 Foreign body in ear
0.650 0.350 0.000
S50-S59 Injuries to the elbow and forearm
0.650 0.350 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.649 0.351 0.000
D74 Methaemoglobinaemia
0.649 0.351 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.649 0.351 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.649 0.351 0.000
M50.8 Other cervical disk disorders
0.649 0.351 0.000
I42.2 Other hypertrophic cardiomyopathy
0.648 0.352 0.000
N28.1 Cyst of kidney, acquired
0.648 0.352 0.000
A41 Other septicaemia
0.648 0.352 0.000
C67 Malignant neoplasm of bladder
0.648 0.352 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.648 0.352 0.000
M45-M49 Spondylopathies
0.648 0.352 0.000
D75.2 Essential thrombocytosis
0.648 0.352 0.000
S71 Open wound of hip and thigh
0.647 0.353 0.000
M54.29 Cervicalgia-Site unspe
0.647 0.353 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.647 0.353 0.000
M54.27 Cervicalgia-Lumbosacral
0.647 0.353 0.000
M54.26 Cervicalgia-Lumbar
0.647 0.353 0.000
M54.25 Cervicalgia-Thoracolumbar
0.647 0.353 0.000
M54.24 Cervicalgia-Thoracic
0.647 0.353 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.647 0.353 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.647 0.353 0.000
M54.20 Cervicalgia-Mult site
0.647 0.353 0.000
M77 Other enthesopathies
0.647 0.353 0.000
M07 Psoriatic and enteropathic arthropathies
0.647 0.353 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.647 0.353 0.000
A02 Other Salmonella infections
0.646 0.354 0.000
I69.3 Sequelae of cerebral infarction
0.646 0.354 0.000
N41 Inflammatory diseases of prostate
0.646 0.354 0.000
D00-D09 In situ neoplasms
0.646 0.354 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.645 0.355 0.000
I63 Cerebral infarction
0.644 0.356 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.644 0.356 0.000
E10 Insulin-dependent diabetes mellitus
0.644 0.356 0.000
A08 Viral and other specified intestinal infections
0.644 0.356 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.642 0.358 0.000
E85 Amyloidosis
0.642 0.358 0.000
E84 Cystic fibrosis
0.642 0.358 0.000
E79 Disorders of purine and pyrimidine metabolism
0.642 0.358 0.000
E77 Disorders of glycoprotein metabolism
0.642 0.358 0.000
E76 Disorders of glycosaminoglycan metabolism
0.642 0.358 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.642 0.358 0.000
E74 Other disorders of carbohydrate metabolism
0.642 0.358 0.000
E72 Other disorders of amino-acid metabolism
0.642 0.358 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.642 0.358 0.000
E70 Disorders of aromatic amino-acid metabolism
0.642 0.358 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.642 0.358 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.642 0.358 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.641 0.359 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.641 0.359 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.641 0.359 0.000
T42.3 Barbiturates
0.641 0.359 0.000
T42.2 Succinimides and oxazolidinediones
0.641 0.359 0.000
T42.1 Iminostilbenes
0.641 0.359 0.000
T42.0 Hydantoin derivatives
0.641 0.359 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.640 0.360 0.000
I51.5 Myocardial degeneration
0.640 0.360 0.000
I51.4 Myocarditis, unspecified
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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