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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7633054
log Bayes Factor = 0.568848
Chromosome 3   position 62,138,954  (GRCh37) Explore rs7633054 on Ensembl!
Variant rs7633054 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VII Diseases of the eye and adnexa
0.711 0.289 0.000
H30-H36 Disorders of choroid and retina
0.710 0.290 0.000
# Top node
0.706 0.294 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.693 0.307 0.000
Chapter II Neoplasms
0.688 0.312 0.000
I30-I52 Other forms of heart disease
0.687 0.313 0.000
Chapter IX Diseases of the circulatory system
0.685 0.315 0.000
H33 Retinal detachments and breaks
0.682 0.318 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.674 0.326 0.000
H35 Other retinal disorders
0.668 0.332 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.667 0.333 0.000
L60-L75 Disorders of skin appendages
0.651 0.349 0.000
S60-S69 Injuries to the wrist and hand
0.644 0.355 0.000
H33.2 Serous retinal detachment
0.643 0.357 0.000
C79 Secondary malignant neoplasm of other sites
0.643 0.357 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.641 0.359 0.000
I50 Heart failure
0.636 0.364 0.000
H40-H42 Glaucoma
0.628 0.372 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.628 0.372 0.000
I51 Complications and ill-defined descriptions of heart disease
0.626 0.374 0.000
H34 Retinal vascular occlusions
0.624 0.376 0.000
H35.8 Other specified retinal disorders
0.619 0.381 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.618 0.382 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.617 0.383 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.615 0.385 0.000
Chapter V Mental and behavioural disorders
0.612 0.388 0.000
I38 Endocarditis, valve unspecified
0.605 0.395 0.000
Chapter VIII Diseases of the ear and mastoid process
0.600 0.400 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.599 0.401 0.000
L72.1 Trichilemmal cyst
0.595 0.405 0.000
I05-I09 Chronic rheumatic heart diseases
0.592 0.408 0.000
I51.7 Cardiomegaly
0.584 0.415 0.000
M70-M79 Other soft tissue disorders
0.584 0.416 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.583 0.417 0.000
L03 Cellulitis
0.582 0.418 0.000
I49 Other cardiac arrhythmias
0.580 0.420 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.579 0.421 0.000
Chapter XXII Codes for special purposes
0.574 0.426 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.570 0.430 0.000
H33.5 Other retinal detachments
0.569 0.431 0.000
H40 Glaucoma
0.569 0.431 0.000
I50.0 Congestive heart failure
0.564 0.436 0.000
M75 Shoulder lesions
0.562 0.438 0.000
H55-H59 Other disorders of eye and adnexa
0.561 0.439 0.000
H43-H45 Disorders of vitreous body and globe
0.555 0.445 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.554 0.446 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.553 0.446 0.000
H35.3 Degeneration of macula and posterior pole
0.552 0.448 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.551 0.449 0.000
I35 Nonrheumatic aortic valve disorders
0.550 0.450 0.000
S61 Open wound of wrist and hand
0.550 0.450 0.000
I45 Other conduction disorders
0.549 0.451 0.000
L81 Other disorders of pigmentation
0.545 0.455 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.544 0.456 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.544 0.456 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.541 0.459 0.000
S70-S79 Injuries to the hip and thigh
0.541 0.459 0.000
I47 Paroxysmal tachycardia
0.534 0.466 0.000
I42 Cardiomyopathy
0.533 0.467 0.000
S00-S09 Injuries to the head
0.530 0.469 0.000
S80-S89 Injuries to the knee and lower leg
0.530 0.470 0.000
C15-C26 Malignant neoplasms of digestive organs
0.527 0.473 0.000
H34.8 Other retinal vascular occlusions
0.527 0.473 0.000
I08 Multiple valve diseases
0.525 0.475 0.000
S69 Other and unspecified injuries of wrist and hand
0.524 0.476 0.000
C64-C68 Malignant neoplasms of urinary tract
0.522 0.478 0.000
S68 Traumatic amputation of wrist and hand
0.521 0.479 0.000
I46 Cardiac arrest
0.519 0.481 0.000
M20-M25 Other joint disorders
0.515 0.485 0.000
H34.2 Other retinal artery occlusions
0.514 0.486 0.000
L08 Other local infections of skin and subcutaneous tissue
0.513 0.487 0.000
I50.1 Left ventricular failure
0.513 0.487 0.000
H40.9 Glaucoma, unspecified
0.511 0.489 0.000
I31 Other diseases of pericardium
0.510 0.490 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.510 0.490 0.000
H10-H13 Disorders of conjunctiva
0.510 0.490 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.509 0.490 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.509 0.491 0.000
H31 Other disorders of choroid
0.509 0.491 0.000
H30 Chorioretinal inflammation
0.509 0.491 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.507 0.492 0.000
L81.4 Other melanin hyperpigmentation
0.506 0.494 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.506 0.494 0.000
S40-S49 Injuries to the shoulder and upper arm
0.505 0.495 0.000
H33.3 Retinal breaks without detachment
0.504 0.496 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.503 0.497 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.503 0.497 0.000
I50.9 Heart failure, unspecified
0.502 0.498 0.000
C80 Malignant neoplasm without specification of site
0.498 0.502 0.000
C60-C63 Malignant neoplasms of male genital organs
0.498 0.502 0.000
L50-L54 Urticaria and erythema
0.497 0.503 0.000
L10-L14 Bullous disorders
0.497 0.503 0.000
C78.0 Secondary malignant neoplasm of lung
0.496 0.504 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.496 0.504 0.000
M75.4 Impingement syndrome of shoulder
0.494 0.506 0.000
H33.0 Retinal detachment with retinal break
0.493 0.507 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.493 0.507 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.493 0.507 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.493 0.507 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.493 0.507 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.493 0.507 0.000
I52 Other heart disorders in diseases classified elsewhere
0.493 0.507 0.000
I48 Atrial fibrillation and flutter
0.493 0.507 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.493 0.507 0.000
I41 Myocarditis in diseases classified elsewhere
0.493 0.507 0.000
I40 Acute myocarditis
0.493 0.507 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.493 0.507 0.000
I37 Pulmonary valve disorders
0.493 0.507 0.000
I36 Nonrheumatic tricuspid valve disorders
0.493 0.507 0.000
I33 Acute and subacute endocarditis
0.493 0.507 0.000
I32 Pericarditis in diseases classified elsewhere
0.493 0.507 0.000
I30 Acute pericarditis
0.493 0.507 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.493 0.507 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.492 0.508 0.000
T66-T78 Other and unspecified effects of external causes
0.492 0.508 0.000
I00-I02 Acute rheumatic fever
0.491 0.509 0.000
D45 Polycythaemia vera
0.491 0.509 0.000
F41 Other anxiety disorders
0.491 0.509 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.491 0.509 0.000
M75.1 Rotator cuff syndrome
0.490 0.510 0.000
F99-F99 Unspecified mental disorder
0.490 0.510 0.000
H02 Other disorders of eyelid
0.490 0.510 0.000
H33.4 Traction detachment of retina
0.489 0.511 0.000
H33.1 Retinoschisis and retinal cysts
0.489 0.511 0.000
L20-L30 Dermatitis and eczema
0.489 0.511 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.488 0.512 0.000
C34 Malignant neoplasm of bronchus and lung
0.486 0.514 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.485 0.515 0.000
H65-H75 Diseases of middle ear and mastoid
0.485 0.515 0.000
H53-H54 Visual disturbances and blindness
0.484 0.516 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.483 0.517 0.000
T79-T79 Certain early complications of trauma
0.483 0.517 0.000
T33-T35 Frostbite
0.483 0.517 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.483 0.517 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.483 0.517 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.483 0.517 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.483 0.517 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.483 0.517 0.000
T00-T07 Injuries involving multiple body regions
0.483 0.517 0.000
S90-S99 Injuries to the ankle and foot
0.483 0.517 0.000
S10-S19 Injuries to the neck
0.483 0.517 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.483 0.517 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.482 0.518 0.000
L60 Nail disorders
0.482 0.518 0.000
H40.2 Primary angle-closure glaucoma
0.482 0.518 0.000
M75.0 Adhesive capsulitis of shoulder
0.482 0.518 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.481 0.519 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.480 0.520 0.000
L89 Decubitus ulcer
0.480 0.520 0.000
H35.9 Retinal disorder, unspecified
0.479 0.521 0.000
H35.7 Separation of retinal layers
0.479 0.521 0.000
H35.6 Retinal haemorrhage
0.479 0.521 0.000
H35.5 Hereditary retinal dystrophy
0.479 0.521 0.000
H35.4 Peripheral retinal degeneration
0.479 0.521 0.000
H35.2 Other proliferative retinopathy
0.479 0.521 0.000
H35.1 Retinopathy of prematurity
0.479 0.521 0.000
H35.0 Background retinopathy and retinal vascular changes
0.479 0.521 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.478 0.522 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.478 0.522 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.476 0.524 0.000
L03.9 Cellulitis, unspecified
0.475 0.525 0.000
L91 Hypertrophic disorders of skin
0.474 0.526 0.000
D46 Myelodysplastic syndromes
0.472 0.528 0.000
M40-M43 Deforming dorsopathies
0.471 0.529 0.000
L03.0 Cellulitis of finger and toe
0.471 0.529 0.000
C51-C58 Malignant neoplasms of female genital organs
0.470 0.530 0.000
H36 Retinal disorders in diseases classified elsewhere
0.470 0.530 0.000
I45.9 Conduction disorder, unspecified
0.469 0.531 0.000
L03.3 Cellulitis of trunk
0.469 0.531 0.000
F41.9 Anxiety disorder, unspecified
0.467 0.533 0.000
L75 Apocrine sweat disorders
0.467 0.533 0.000
L74 Eccrine sweat disorders
0.467 0.533 0.000
L73 Other follicular disorders
0.467 0.533 0.000
L71 Rosacea
0.467 0.533 0.000
L70 Acne
0.467 0.533 0.000
L68 Hypertrichosis
0.467 0.533 0.000
L67 Hair colour and hair shaft abnormalities
0.467 0.533 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.467 0.533 0.000
L65 Other nonscarring hair loss
0.467 0.533 0.000
L64 Androgenic alopecia
0.467 0.533 0.000
L63 Alopecia areata
0.467 0.533 0.000
L62 Nail disorders in diseases classified elsewhere
0.467 0.533 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.466 0.534 0.000
M05-M14 Inflammatory polyarthropathies
0.466 0.534 0.000
S20-S29 Injuries to the thorax
0.463 0.536 0.000
S62 Fracture at wrist and hand level
0.463 0.537 0.000
S67 Crushing injury of wrist and hand
0.462 0.538 0.000
S65 Injury of blood vessels at wrist and hand level
0.462 0.538 0.000
S64 Injury of nerves at wrist and hand level
0.462 0.538 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.462 0.538 0.000
S60 Superficial injury of wrist and hand
0.462 0.538 0.000
I49.9 Cardiac arrhythmia, unspecified
0.461 0.539 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.461 0.539 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.461 0.539 0.000
C79.6 Secondary malignant neoplasm of ovary
0.461 0.539 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.461 0.539 0.000
C79.2 Secondary malignant neoplasm of skin
0.461 0.539 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.461 0.539 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.461 0.539 0.000
H60-H62 Diseases of external ear
0.461 0.539 0.000
M65-M68 Disorders of synovium and tendon
0.460 0.539 0.000
L05 Pilonidal cyst
0.459 0.540 0.000
L04 Acute lymphadenitis
0.459 0.540 0.000
L01 Impetigo
0.459 0.540 0.000
L00 Staphylococcal scalded skin syndrome
0.459 0.540 0.000
C18 Malignant neoplasm of colon
0.458 0.541 0.000
I35.0 Aortic (valve) stenosis
0.458 0.542 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.457 0.543 0.000
C78.2 Secondary malignant neoplasm of pleura
0.457 0.543 0.000
O00-O08 Pregnancy with abortive outcome
0.457 0.543 0.000
I49.4 Other and unspecified premature depolarisation
0.457 0.543 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.456 0.544 0.000
I47.1 Supraventricular tachycardia
0.455 0.545 0.000
C78.7 Secondary malignant neoplasm of liver
0.454 0.546 0.000
H57 Other disorders of eye and adnexa
0.453 0.547 0.000
H80-H83 Diseases of inner ear
0.453 0.547 0.000
H42 Glaucoma in diseases classified elsewhere
0.450 0.549 0.000
M71 Other bursopathies
0.450 0.550 0.000
S61.8 Open wound of other parts of wrist and hand
0.450 0.550 0.000
I60-I69 Cerebrovascular diseases
0.450 0.550 0.000
I51.6 Cardiovascular disease, unspecified
0.449 0.551 0.000
I51.5 Myocardial degeneration
0.449 0.551 0.000
I51.4 Myocarditis, unspecified
0.449 0.551 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.449 0.551 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.449 0.551 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.449 0.551 0.000
I51.0 Cardiac septal defect, acquired
0.449 0.551 0.000
H34.9 Retinal vascular occlusion, unspecified
0.448 0.552 0.000
H34.1 Central retinal artery occlusion
0.448 0.552 0.000
H34.0 Transient retinal artery occlusion
0.448 0.552 0.000
S72 Fracture of femur
0.446 0.554 0.000
M80-M85 Disorders of bone density and structure
0.445 0.555 0.000
I51.9 Heart disease, unspecified
0.445 0.555 0.000
H43 Disorders of vitreous body
0.444 0.556 0.000
I51.8 Other ill-defined heart diseases
0.443 0.556 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.443 0.557 0.000
L72.2 Steatocystoma multiplex
0.443 0.557 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.443 0.557 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.443 0.557 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.443 0.557 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.443 0.557 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.443 0.557 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.443 0.557 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.443 0.557 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.443 0.557 0.000
H90-H95 Other disorders of ear
0.442 0.558 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.441 0.559 0.000
M91-M94 Chondropathies
0.441 0.559 0.000
M86-M90 Other osteopathies
0.441 0.559 0.000
M60-M63 Disorders of muscles
0.441 0.559 0.000
M00-M03 Infectious arthropathies
0.441 0.559 0.000
H04 Disorders of lachrymal system
0.441 0.559 0.000
L03.1 Cellulitis of other parts of limb
0.440 0.560 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.440 0.560 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.439 0.561 0.000
F80-F89 Disorders of psychological development
0.439 0.561 0.000
F70-F79 Mental retardation
0.439 0.561 0.000
F60-F69 Disorders of adult personality and behaviour
0.439 0.561 0.000
C50-C50 Malignant neoplasm of breast
0.438 0.562 0.000
S69.9 Unspecified injury of wrist and hand
0.438 0.562 0.000
M23 Internal derangement of knee
0.437 0.563 0.000
F40 Phobic anxiety disorders
0.437 0.563 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.435 0.565 0.000
I42.0 Dilated cardiomyopathy
0.435 0.565 0.000
S61.0 Open wound of finger(s) without damage to nail
0.435 0.565 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.433 0.567 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.429 0.571 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.429 0.571 0.000
L94 Other localised connective tissue disorders
0.429 0.571 0.000
L93 Lupus erythematosus
0.429 0.571 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.429 0.571 0.000
L87 Transepidermal elimination disorders
0.429 0.571 0.000
L85 Other epidermal thickening
0.429 0.571 0.000
L88 Pyoderma gangrenosum
0.429 0.571 0.000
L86 Keratoderma in diseases classified elsewhere
0.429 0.571 0.000
L84 Corns and callosities
0.429 0.571 0.000
L83 Acanthosis nigricans
0.429 0.571 0.000
L80 Vitiligo
0.429 0.571 0.000
D41.4 Bladder
0.429 0.571 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.429 0.571 0.000
H02.8 Other specified disorders of eyelid
0.429 0.571 0.000
D00-D09 In situ neoplasms
0.428 0.572 0.000
C92 Myeloid leukaemia
0.428 0.572 0.000
S82 Fracture of lower leg, including ankle
0.427 0.572 0.000
I49.0 Ventricular fibrillation and flutter
0.427 0.572 0.000
S50-S59 Injuries to the elbow and forearm
0.427 0.573 0.000
I49.8 Other specified cardiac arrhythmias
0.427 0.573 0.000
T90 Sequelae of injuries of head
0.425 0.575 0.000
I09 Other rheumatic heart diseases
0.424 0.576 0.000
I07 Rheumatic tricuspid valve diseases
0.424 0.576 0.000
I06 Rheumatic aortic valve diseases
0.424 0.576 0.000
I05 Rheumatic mitral valve diseases
0.424 0.576 0.000
T92 Sequelae of injuries of upper limb
0.424 0.576 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.423 0.577 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.422 0.578 0.000
S00 Superficial injury of head
0.422 0.578 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.422 0.578 0.000
H18 Other disorders of cornea
0.420 0.580 0.000
M25 Other joint disorders, not elsewhere classified
0.419 0.581 0.000
M77 Other enthesopathies
0.419 0.581 0.000
M76 Enthesopathies of lower limb, excluding foot
0.419 0.581 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.419 0.581 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.419 0.581 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.418 0.582 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.418 0.582 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.418 0.582 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.418 0.582 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.418 0.582 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.418 0.582 0.000
L40-L45 Papulosquamous disorders
0.417 0.582 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.417 0.583 0.000
L03.8 Cellulitis of other sites
0.417 0.583 0.000
L03.2 Cellulitis of face
0.417 0.583 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.416 0.584 0.000
I49.5 Sick sinus syndrome
0.416 0.584 0.000
I49.3 Ventricular premature depolarisation
0.416 0.584 0.000
I49.2 Junctional premature depolarisation
0.416 0.584 0.000
I49.1 Atrial premature depolarisation
0.416 0.584 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.415 0.585 0.000
H05 Disorders of orbit
0.415 0.585 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.415 0.585 0.000
H01 Other inflammation of eyelid
0.415 0.585 0.000
Chapter XX External causes of morbidity and mortality
0.414 0.585 0.000
I44 Atrioventricular and left bundle-branch block
0.414 0.586 0.000
U80 Agent resistant to penicillin and related antibiotics
0.413 0.587 0.000
S01 Open wound of head
0.412 0.588 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.412 0.588 0.000
I34 Nonrheumatic mitral valve disorders
0.411 0.589 0.000
C34.3 Lower lobe, bronchus or lung
0.409 0.591 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.409 0.591 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.409 0.591 0.000
C32 Malignant neoplasm of larynx
0.409 0.591 0.000
C31 Malignant neoplasm of accessory sinuses
0.409 0.591 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.409 0.591 0.000
C37 Malignant neoplasm of thymus
0.409 0.591 0.000
C33 Malignant neoplasm of trachea
0.409 0.591 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.409 0.591 0.000
H40.8 Other glaucoma
0.408 0.592 0.000
H40.6 Glaucoma secondary to drugs
0.408 0.592 0.000
H40.5 Glaucoma secondary to other eye disorders
0.408 0.592 0.000
H40.4 Glaucoma secondary to eye inflammation
0.408 0.592 0.000
H40.3 Glaucoma secondary to eye trauma
0.408 0.592 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.407 0.592 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.407 0.593 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.406 0.594 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.405 0.595 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.404 0.596 0.000
M75.8 Other shoulder lesions
0.403 0.597 0.000
M75.9 Shoulder lesion, unspecified
0.403 0.597 0.000
M75.3 Calcific tendinitis of shoulder
0.403 0.597 0.000
M75.2 Bicipital tendinitis
0.403 0.597 0.000
F99 Mental disorder, not otherwise specified
0.403 0.597 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.402 0.598 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.402 0.598 0.000
H55 Nystagmus and other irregular eye movements
0.402 0.598 0.000
M75.5 Bursitis of shoulder
0.401 0.599 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.398 0.602 0.000
H44 Disorders of globe
0.398 0.602 0.000
I46.0 Cardiac arrest with successful resuscitation
0.398 0.602 0.000
M22 Disorders of patella
0.398 0.602 0.000
O85-O92 Complications predominantly related to the puerperium
0.397 0.603 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.397 0.603 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.397 0.603 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.397 0.603 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.397 0.603 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.397 0.603 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.397 0.603 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.397 0.603 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.397 0.603 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.397 0.603 0.000
O80-O84 Delivery
0.396 0.604 0.000
C18.0 Caecum
0.395 0.605 0.000
F48 Other neurotic disorders
0.395 0.605 0.000
F45 Somatoform disorders
0.395 0.605 0.000
F44 Dissociative [conversion] disorders
0.395 0.605 0.000
F43 Reaction to severe stress, and adjustment disorders
0.395 0.605 0.000
F42 Obsessive-compulsive disorder
0.395 0.605 0.000
I08.0 Disorders of both mitral and aortic valves
0.395 0.605 0.000
I31.9 Disease of pericardium, unspecified
0.395 0.605 0.000
I35.9 Aortic valve disorder, unspecified
0.394 0.605 0.000
I35.8 Other aortic valve disorders
0.394 0.605 0.000
C43 Malignant melanoma of skin
0.395 0.605 0.000
C16 Malignant neoplasm of stomach
0.394 0.605 0.000
S61.7 Multiple open wounds of wrist and hand
0.394 0.606 0.000
I45.8 Other specified conduction disorders
0.394 0.606 0.000
I45.6 Preexcitation syndrome
0.394 0.606 0.000
I45.5 Other specified heart block
0.394 0.606 0.000
I45.4 Nonspecific intraventricular block
0.394 0.606 0.000
I45.3 Trifascicular block
0.394 0.606 0.000
I45.2 Bifascicular block
0.394 0.606 0.000
I45.0 Right fascicular block
0.394 0.606 0.000
M45-M49 Spondylopathies
0.393 0.607 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.393 0.607 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.393 0.607 0.000
I27 Other pulmonary heart diseases
0.392 0.608 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.391 0.609 0.000
L81.9 Disorder of pigmentation, unspecified
0.391 0.609 0.000
L81.8 Other specified disorders of pigmentation
0.391 0.609 0.000
L81.7 Pigmented purpuric dermatosis
0.391 0.609 0.000
L81.6 Other disorders of diminished melanin formation
0.391 0.609 0.000
L81.5 Leukoderma, not elsewhere classified
0.391 0.609 0.000
L81.3 Cafe au lait spots
0.391 0.609 0.000
L81.2 Freckles
0.391 0.609 0.000
L81.1 Chloasma
0.391 0.609 0.000
L81.0 Postinflammatory hyperpigmentation
0.391 0.609 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.390 0.609 0.000
C95 Leukaemia of unspecified cell type
0.390 0.609 0.000
C94 Other leukaemias of specified cell type
0.390 0.609 0.000
C93 Monocytic leukaemia
0.390 0.609 0.000
C91 Lymphoid leukaemia
0.390 0.609 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.390 0.609 0.000
C88 Malignant immunoproliferative diseases
0.390 0.609 0.000
C86 Other specified types of T/NK-cell lymphoma
0.390 0.609 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.390 0.609 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.390 0.609 0.000
C81 Hodgkin's disease
0.390 0.609 0.000
H40.1 Primary open-angle glaucoma
0.390 0.610 0.000
T98 Sequelae of other and unspecified effects of external causes
0.390 0.610 0.000
T95 Sequelae of burns, corrosions and frostbite
0.390 0.610 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.390 0.610 0.000
T93 Sequelae of injuries of lower limb
0.390 0.610 0.000
T91 Sequelae of injuries of neck and trunk
0.390 0.610 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.390 0.610 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.390 0.610 0.000
I72 Other aneurysm
0.390 0.610 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.389 0.611 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.389 0.611 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.388 0.612 0.000
H21 Other disorders of iris and ciliary body
0.388 0.612 0.000
H20 Iridocyclitis
0.388 0.612 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.388 0.612 0.000
H17 Corneal scars and opacities
0.388 0.612 0.000
H16 Keratitis
0.388 0.612 0.000
H15 Disorders of sclera
0.388 0.612 0.000
S79 Other and unspecified injuries of hip and thigh
0.388 0.612 0.000
S78 Traumatic amputation of hip and thigh
0.388 0.612 0.000
S77 Crushing injury of hip and thigh
0.388 0.612 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.388 0.612 0.000
S75 Injury of blood vessels at hip and thigh level
0.388 0.612 0.000
S74 Injury of nerves at hip and thigh level
0.388 0.612 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.388 0.612 0.000
S71 Open wound of hip and thigh
0.388 0.612 0.000
S70 Superficial injury of hip and thigh
0.388 0.612 0.000
L91.0 Keloid scar
0.388 0.612 0.000
D48.1 Connective and other soft tissue
0.387 0.613 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.385 0.615 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.384 0.616 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.384 0.616 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.383 0.617 0.000
I47.0 Reentry ventricular arrhythmia
0.383 0.617 0.000
M72 Fibroblastic disorders
0.383 0.617 0.000
I42.8 Other cardiomyopathies
0.382 0.618 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.382 0.618 0.000
I42.6 Alcoholic cardiomyopathy
0.382 0.618 0.000
I42.5 Other restrictive cardiomyopathy
0.382 0.618 0.000
I42.4 Endocardial fibroelastosis
0.382 0.618 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.382 0.618 0.000
I42.2 Other hypertrophic cardiomyopathy
0.382 0.618 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.382 0.618 0.000
S08 Traumatic amputation of part of head
0.380 0.619 0.000
S07 Crushing injury of head
0.380 0.619 0.000
S06 Intracranial injury
0.380 0.619 0.000
S05 Injury of eye and orbit
0.380 0.619 0.000
S04 Injury of cranial nerves
0.380 0.619 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.380 0.619 0.000
S02 Fracture of skull and facial bones
0.380 0.619 0.000
S89 Other and unspecified injuries of lower leg
0.380 0.620 0.000
S88 Traumatic amputation of lower leg
0.380 0.620 0.000
S87 Crushing injury of lower leg
0.380 0.620 0.000
S86 Injury of muscle and tendon at lower leg level
0.380 0.620 0.000
S85 Injury of blood vessels at lower leg level
0.380 0.620 0.000
S84 Injury of nerves at lower leg level
0.380 0.620 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.380 0.620 0.000
S81 Open wound of lower leg
0.380 0.620 0.000
S80 Superficial injury of lower leg
0.380 0.620 0.000
H02.9 Disorder of eyelid, unspecified
0.380 0.620 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.380 0.620 0.000
H66 Suppurative and unspecified otitis media
0.379 0.621 0.000
H50 Other strabismus
0.379 0.621 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.378 0.622 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.378 0.622 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.378 0.622 0.000
C21 Malignant neoplasm of anus and anal canal
0.378 0.622 0.000
C17 Malignant neoplasm of small intestine
0.378 0.622 0.000
C23 Malignant neoplasm of gallbladder
0.378 0.622 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.377 0.623 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.377 0.623 0.000
I08.9 Multiple valve disease, unspecified
0.376 0.623 0.000
I08.8 Other multiple valve diseases
0.376 0.623 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.376 0.623 0.000
H57.1 Ocular pain
0.376 0.624 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.376 0.624 0.000
S69.8 Other specified injuries of wrist and hand
0.376 0.624 0.000
S69.7 Multiple injuries of wrist and hand
0.376 0.624 0.000
M24 Other specific joint derangements
0.376 0.624 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.375 0.625 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.374 0.626 0.000
C66 Malignant neoplasm of ureter
0.374 0.626 0.000
C65 Malignant neoplasm of renal pelvis
0.374 0.626 0.000
S61.1 Open wound of finger(s) with damage to nail
0.374 0.626 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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